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Chiara Troffa

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Nicola Glorioso; Samir Patel; Mathew Thomas; Chiara Troffa; Giuseppe Argiolas; Inyoung Baek; Jack Zhang
Antihypertensive efficacy and tolerability of aliskiren/amlodipine single- pill combinations in patients with an inadequate response to aliskiren monotherapy.
Nicola Glorioso; Victoria L M Herrera; Chiara Troffa; Giuseppe Argiolas; Emanuela Bulla; Patrizia Bulla; Tamara Didishvili; Nelson Ruiz-Opazo
DEspR T/CATAAAA-box promoter variant decreases DEspR transcription and is associated with increased BP in Sardinian males.
Fabiana Filigheddu; Giuseppe Argiolas; Simona Degortes; Roberta Zaninello; Francesca Frau; Silvia Pitzoi; Emanuela Bulla; Patrizia Bulla; Chiara Troffa; Nicola Glorioso
Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension.

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All Publications

2012: Nicola Glorioso; Samir Patel; Mathew Thomas; Chiara Troffa; Giuseppe Argiolas; Inyoung Baek; Jack Zhang
Antihypertensive efficacy and tolerability of aliskiren/amlodipine single- pill combinations in patients with an inadequate response to aliskiren monotherapy.
Current vascular pharmacology 2012;10(6):748-55.
2011: Nicola Glorioso; Victoria L M Herrera; Chiara Troffa; Giuseppe Argiolas; Emanuela Bulla; Patrizia Bulla; Tamara Didishvili; Nelson Ruiz-Opazo
DEspR T/CATAAAA-box promoter variant decreases DEspR transcription and is associated with increased BP in Sardinian males.
Physiological genomics 2011;43(21):1219-25.
2010: Fabiana Filigheddu; Giuseppe Argiolas; Simona Degortes; Roberta Zaninello; Francesca Frau; Silvia Pitzoi; Emanuela Bulla; Patrizia Bulla; Chiara Troffa; Nicola Glorioso
Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension.
Pharmacogenomics 2010;11(3):319-25.
2009: Fabiana Filigheddu; Fabiana Quagliarini; Filomena Campagna; Tanuccia Secci; Simona Degortes; Roberta Zaninello; Giuseppe Argiolas; Roberto Verna; Silvia Pitzoi; Francesca Frau; Chiara Troffa; Emanuela Bulla; Stefano Bertolini; Nicola Glorioso; Marcello Arca
Prevalence and clinical features of heterozygous carriers of autosomal recessive hypercholesterolemia in Sardinia.
Atherosclerosis 2009;207(1):162-7.
2008: Fabiana Filigheddu; Giuseppe Argiolas; Emanuela Bulla; Chiara Troffa; Patrizia Bulla; Simone Fadda; Roberta Zaninello; Simona Degortes; Francesca Frau; Silvia Pitzoi; Nicola Glorioso
Clinical variables, not RAAS polymorphisms, predict blood pressure response to ACE inhibitors in Sardinians.
Pharmacogenomics 2008;9(10):1419-27.
2007: Nicola Glorioso; Giuseppe Argiolas; Fabiana Filigheddu; Chiara Troffa; F Cocco; E Bulla; P Bulla; R Zaninello; S Degortes; S Pitzoi; F Frau; S Fadda; P Pinna Parpaglia; G Bernini; M Bardini; F Fallo; L Malatino; G Regolisti; C Ferri; Daniele Cusi; A Sciacqua; F Perticone; E Degli Esposti; C Baraccani; G Parati; Franco Veglio; Paolo Mulatero; T A Williams; F Macciardi; B Stancanelli
Conceptual basis and methodology of the SOPHIA study.
Pharmacogenomics 2007;8(11):1497-509.
2007: Nicola Glorioso; Victoria L M Herrera; Pia Bagamasbad; Fabiana Filigheddu; Chiara Troffa; Giuseppe Argiolas; Emanuela Bulla; Julius L Decano; Nelson Ruiz-Opazo
Association of ATP1A1 and dear single-nucleotide polymorphism haplotypes with essential hypertension: sex-specific and haplotype-specific effects.
Circulation research 2007;100(10):1522-9.
2006: Fabiana Filigheddu; Chiara Troffa; Nicola Glorioso
Pharmacogenomics of essential hypertension: are we going the right way?
Cardiovascular & hematological agents in medicinal chemistry 2006;4(1):7-15.
2005: Nicola Glorioso; Fabiana Filigheddu; Paolo Pinna Parpaglia; Aldo Soro; Chiara Troffa; Giuseppe Argiolas; Paolo Mulatero
11beta-Hydroxysteroid dehydrogenase type 2 activity is associated with left ventricular mass in essential hypertension.
European heart journal 2005;26(5):498-504.
2005: Tracy A Williams; Paolo Mulatero; Fabiana Filigheddu; Chiara Troffa; Milan Alberto; Giuseppe Argiolas; Paolo Pinna Parpaglia; Franco Veglio; Nicola Glorioso
Role of HSD11B2 polymorphisms in essential hypertension and the diuretic response to thiazides.
Kidney international 2005;67(2):631-7.
2004: Fabiana Filigheddu; J E Reid; Chiara Troffa; P PinnaParpaglia; Giuseppe Argiolas; A Testa; Mark H Skolnick; Nicola Glorioso
Genetic polymorphisms of the beta-adrenergic system: association with essential hypertension and response to beta-blockade.
The pharmacogenomics journal 2004;4(3):154-60.
2002: Nicola Glorioso; Fabiana Filigheddu; Daniele Cusi; Chiara Troffa; Milena Conti; Marcella Natalizio; Giuseppe Argiolas; Cristina Barlassina; Giuseppe Bianchi
alpha-Adducin 460Trp allele is associated with erythrocyte Na transport rate in North Sardinian primary hypertensives.
Hypertension 2002;39(2 Pt 2):357-62.
2001: Y Song; Victoria L M Herrera; Fabiana Filigheddu; Chiara Troffa; Lyle V Lopez; Nicola Glorioso; Nelson Ruiz-Opazo
Non-association of the thiazide-sensitive Na,Cl-cotransporter gene with polygenic hypertension in both rats and humans.
Journal of hypertension 2001;19(9):1547-51.
2001: Nicola Glorioso; Fabiana Filigheddu; Chiara Troffa; Aldo Soro; Paolo Pinna Parpaglia; Aristides Tsikoudakis; Richard H Myers; Victoria L M Herrera; Nelson Ruiz-Opazo
Interaction of alpha(1)-Na,K-ATPase and Na,K,2Cl-cotransporter genes in human essential hypertension.
Hypertension 2001;38(2):204-9.
1999: Nicola Glorioso; Chiara Troffa; Fabiana Filigheddu; F Dettori; Aldo Soro; Paolo Pinna Parpaglia; S Collatina; M Pahor
Effect of the HMG-CoA reductase inhibitors on blood pressure in patients with essential hypertension and primary hypercholesterolemia.
Hypertension 1999;34(6):1281-6.
1999: Nicola Glorioso; Chiara Troffa; Giancarlo Tonolo; Fabiana Filigheddu; F Dettori; Milco Ciccarese; Alois Saller; Aldo Soro; Enrico Brocco; P Pinna-Parpaglia; Franco Mantero; P P Faronato; Romano Nosadini; Mario Maioli
High plasma prorenin in non diabetic siblings of non insulin-dependent diabetes mellitus patients.
Journal of endocrinological investigation 1999;22(10):760-5.
1999: Nicola Glorioso; Paolo Manunta; Fabiana Filigheddu; Chiara Troffa; Paola Stella; Cristina Barlassina; C Lombardi; Aldo Soro; F Dettori; Paolo Pinna Parpaglia; M T Alibrandi; Daniele Cusi; Giuseppe Bianchi
The role of alpha-adducin polymorphism in blood pressure and sodium handling regulation may not be excluded by a negative association study.
Hypertension 1999;34(4 Pt 1):649-54.
1997: Daniele Cusi; Cristina Barlassina; T Azzani; Giorgio Casari; Lorena Citterio; M Devoto; Nicola Glorioso; Chiara Lanzani; Paolo Manunta; M Righetti; R Rivera; Paola Stella; Chiara Troffa; Laura Zagato; Giuseppe Bianchi
Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension.
Lancet 1997;349(9062):1353-7.
1995: Nicola Glorioso; Giancarlo Tonolo; Chiara Troffa; Aldo Soro; Paolo Manunta; Paolo Madeddu; G Sabino; P Pinna-Parpaglia; G Realdi
Recognition of markers of response to potassium-canrenoate in essential hypertension.
Steroids 1995;60(1):105-9.
1993: Paolo Madeddu; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; Giancarlo Tonolo; Chiara Troffa; Nicola Glorioso
Bradykinin B2-receptor blockade facilitates deoxycorticosterone-salt hypertension.
Hypertension 1993;21(6 Pt 2):980-4.
1993: Giancarlo Tonolo; Aldo Soro; Paolo Madeddu; Chiara Troffa; Maria Grazia Melis; G Patteri; Paolo Pinna Parpaglia; G Sabino; Mario Maioli; Nicola Glorioso
Effect of chronic intracerebroventricular dexamethasone on blood pressure in normotensive rats.
The American journal of physiology 1993;264(6 Pt 1):E843-7.
1993: Nicola Glorioso; Maria Grazia Melis; Paolo Manunta; Chiara Troffa; Giancarlo Tonolo; Aldo Soro; Paolo Madeddu; A Pazzola; F Pala; Daniele Cusi
Different sensitivity to hydrochlorothiazide and to potassium-canrenoate among essential hypertensive patients.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1993;15 Suppl 1():187-96.
1992: Paolo Madeddu; Vittorio Anania; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; G Pisanu; Chiara Troffa; Giancarlo Tonolo; Nicola Glorioso
Effects of Hoe 140, a bradykinin B2-receptor antagonist, on renal function in conscious normotensive rats.
British journal of pharmacology 1992;106(2):380-6.
1992: Paolo Madeddu; Vittorio Anania; S Alagna; Chiara Troffa; Paolo Pinna Parpaglia; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni; C Fattaccio; Nicola Glorioso
Role of brain kallikrein-kinin system in regulation of adrenocorticotropin release.
The American journal of physiology 1992;262(3 Pt 1):E312-8.
1991: Paolo Madeddu; Vittorio Anania; Paolo Pinna Parpaglia; Chiara Troffa; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni
Endothelin-1-induced renal vasoconstriction is blunted by enalaprilat and enhanced by EDRF antagonist in awake normotensive rats.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(6):600-6.
1991: Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; A Pazzola; Aldo Soro; Paolo Madeddu; F Pala; Maria Grazia Melis; P PinnaParpaglia; G Patteri
Prorenin is present in human red blood cells.
Canadian journal of physiology and pharmacology 1991;69(9):1394-7.
1991: Chiara Troffa; Giancarlo Tonolo; Maria Grazia Melis; Paolo Manunta; Aldo Soro; F Pala; A Pazzola; G Sabino; A Masala; Mario Maioli
Effect of angiotensin converting enzyme inhibition on the menstrual cycle of hypertensive women.
Journal of cardiovascular pharmacology 1991;18(3):462-7.
1990: Paolo Madeddu; X P Yang; Vittorio Anania; Chiara Troffa; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni
Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin.
The American journal of physiology 1990;259(2 Pt 2):F304-11.
1990: Paolo Madeddu; F Pala; Chiara Troffa; P Pinna Parpaglia; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Grazia Melis; Maria Piera Demontis
[Protective effect of a calcium antagonist against renal vasoconstriction induced by endothelin in the normotensive rat].
Bollettino della Società italiana di biologia sperimentale 1990;66(7):671-8.
1990: Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; P Pinna Parpaglia; Paolo Madeddu; Maria Grazia Melis; Aldo Soro; F Pala; A Pazzola; G Patteri
[Effect of chronic enalapril treatment on prorenin, renin and sex hormones during the menstrual cycle in patients with essential hypertension].
Bollettino della Società italiana di biologia sperimentale 1990;66(7):663-70.
1990: Maria Grazia Melis; Chiara Troffa; Paolo Manunta; P Pinna Parpaglia; Aldo Soro; F Pala; Paolo Madeddu; A Pazzola; Giancarlo Tonolo; G Patteri
[Effect of menstrual cycle hormones on cation transport in the red-cell membrane].
Bollettino della Società italiana di biologia sperimentale 1990;66(7):679-84.
1990: Paolo Madeddu; Nicola Glorioso; Aldo Soro; Giancarlo Tonolo; Paolo Manunta; Chiara Troffa; Maria Piera Demontis; Maria Vittoria Varoni; Vittorio Anania
Brain kinins are responsible for the pressor effect of intracerebroventricular captopril in spontaneously hypertensive rats.
Hypertension 1990;15(4):407-12.
1990: Paolo Madeddu; Nicola Glorioso; Aldo Soro; Paolo Manunta; Chiara Troffa; Giancarlo Tonolo; M Grazia Melis; A Pazzola
Effect of a kinin antagonist on renal function and haemodynamics during alterations in sodium balance in conscious normotensive rats.
Clinical science (London, England : 1979) 1990;78(2):165-8.
1990: Giancarlo Tonolo; M McMillan; A M Richards; P Montorsi; Jorge Polonia; Aldo Soro; Chiara Troffa; Nicola Glorioso
Changes in plasma atrial natriuretic factor during sequential fluid removal and biochemical correction in end-stage chronic renal failure patients.
Nephron 1990;55(1):58-62.
1989: Nicola Glorioso; Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; Paolo Madeddu; Maria Grazia Melis; A Pazzola; F Pala; Mario Maioli; P Mameli
Activation of human prorenin by lipidic constituents of the cell membrane.
American journal of hypertension 1989;2(12 Pt 1):920-3.
1989: Nicola Glorioso; Chiara Troffa; Giancarlo Tonolo; Maria Grazia Melis; Paolo Manunta; Aldo Soro; Paolo Madeddu; A Pazzola; F Pàla
Stimulation of plasma inactive renin by dexamethasone in the cat.
The American journal of physiology 1989;257(6 Pt 1):E879-84.
1989: Chiara Troffa; Giancarlo Tonolo; Aldo Soro; Paolo Manunta; Maria Grazia Melis; A Pazzola; F Pala; Paolo Madeddu; S Alagna; A Masala
Circulating prorenin and renin in response to intravenous adrenocorticotrophic hormone in essential hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(6):S226-7.
1989: Giancarlo Tonolo; Aldo Soro; V Scardaccio; Chiara Troffa; A Pazzola; Paolo Manunta; Maria Grazia Melis; F Pala; Paolo Madeddu; P P Rovasio
Correlates of atrial natriuretic factor in chronic renal failure.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(6):S238-9.
1989: Paolo Madeddu; Chiara Troffa; Nicola Glorioso; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni; Vittorio Anania
Effect of endothelin on regional hemodynamics and renal function in awake normotensive rats.
Journal of cardiovascular pharmacology 1989;14(6):818-25.
1989: Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; A Pazzola; Maria Grazia Melis; F Pala; Aldo Soro; Paolo Madeddu; Nicola Glorioso
[Possible activation of human prorenin by contact with the cell membrane].
Bollettino della Società italiana di biologia sperimentale 1989;65(11):1017-23.
1989: Paolo Manunta; Maria Grazia Melis; Aldo Soro; A Pazzola; Chiara Troffa; S Motzo; F Pala; Paolo Madeddu; Giancarlo Tonolo; Nicola Glorioso
[Erythrocyte cation transport in arterial hypertension: interrelation with the renin-angiotensin-aldosterone system and the atrial natriuretic factor].
Bollettino della Società italiana di biologia sperimentale 1989;65(11):1009-16.
1989: Giancarlo Tonolo; A M Richards; Paolo Manunta; Chiara Troffa; A Pazzola; Paolo Madeddu; A Towrie; Robert Fraser; Nicola Glorioso
Low-dose infusion of atrial natriuretic factor in mild essential hypertension.
Circulation 1989;80(4):893-902.
1988: N Glorioso; Chiara Troffa; Giancarlo Tonolo
Prorenin in the cells of the mature human ovarian follicle.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(6):1325-7.
1988: Nicola Glorioso; Paolo Manunta; Chiara Troffa; A Pazzola; Aldo Soro; F Pala; Maria Grazia Melis; Paolo Madeddu; Giancarlo Tonolo
Effects of nitrendipine on blood pressure, renin-angiotensin system, and kidney function in essential hypertension.
Journal of cardiovascular pharmacology 1988;12 Suppl 4():S142-5.
1987: Paolo Madeddu; M Oppes; Aldo Soro; P Dessi'-Fulgheri; Nicola Glorioso; F Bandiera; Paolo Manunta; S Rubattu; Chiara Troffa; Giancarlo Tonolo
Natriuretic effect of acute nifedipine administration is not mediated by the renal kallikrein-kinin system.
Journal of cardiovascular pharmacology 1987;9(5):536-40.