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Ming-Daw Tsai

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Physiology

Site-Directed Mutagenesis

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Amino Acid Sequence

Living Beings

Cattle

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Biomolecular Nuclear Magnetic Resonance

Anatomy

Pancreas

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Co-Publications
Name
23
Byeon, In-Ja
17
Li, Junan
16
Bruzik, Karol
15
Yuan, Chunhua
14
Poi, Ming-Jye
11
Jain, Mahendra
8
Sundaralingam, Muttaiya
7
Yongkiettrakul, Suganya
7
Showalter, Alexander
7
Lamarche, Brandon
6
Mahajan, Anjali
6
Bakhtina, Marina
6
Selby, TL
6
Sekar, Kanagaraj
6
Velmurugan, Devadasan

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Publications

TOP 3
Bai Chuan; Zhao Li; Rebecchi Mario; Tsai Ming-Daw; Bruzik Karol S
Trans-cyclization of phosphatidylinositol catalyzed by phospholipase C from Streptomyces antibioticus.
Guo Yi; Mahajan Anjali; Yuan Chunhua; Joo Sang Hoon; Weghorst Christopher M; Tsai Ming-Daw; Li Junan
Comparisons of the conformational stability of cyclin-dependent kinase (CDK) 4-interacting ankyrin repeat (AR) proteins.
Bakhtina Marina; Roettger Michelle P; Tsai Ming-Daw
Contribution of the reverse rate of the conformational step to polymerase beta fidelity.

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All Publications

2009: Bai Chuan; Zhao Li; Rebecchi Mario; Tsai Ming-Daw; Bruzik Karol S
Trans-cyclization of phosphatidylinositol catalyzed by phospholipase C from Streptomyces antibioticus.
Journal of the American Chemical Society 2009;131(24):8362-3.
2009: Guo Yi; Mahajan Anjali; Yuan Chunhua; Joo Sang Hoon; Weghorst Christopher M; Tsai Ming-Daw; Li Junan
Comparisons of the conformational stability of cyclin-dependent kinase (CDK) 4-interacting ankyrin repeat (AR) proteins.
Biochemistry 2009;48(19):4050-62.
2009: Bakhtina Marina; Roettger Michelle P; Tsai Ming-Daw
Contribution of the reverse rate of the conformational step to polymerase beta fidelity.
Biochemistry 2009;48(14):3197-208.
2009: Chen Zhen; Peng I-Chen; Sun Wei; Su Mei-I; Hsu Pang-Hung; Fu Yi; Zhu Yi; DeFea Kathryn; Pan Songqin; Tsai Ming-Daw; Shyy John Y-J
AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633.
Circulation research 2009;104(4):496-505.
2009: Wu Ming-Fang; Yang Chih-Ya; Lin Tzu-Lung; Wang Jin-Town; Yang Feng-Ling; Wu Shih-Hsiung; Hu Bor-Shen; Chou Teh-Ying; Tsai Ming-Daw; Lin Chi-Hung; Hsieh Shie-Liang
Humoral immunity against capsule polysaccharide protects the host from magA+ Klebsiella pneumoniae-induced lethal disease by evading Toll-like receptor 4 signaling.
Infection and immunity 2009;77(2):615-21.
2008: Roettger Michelle P; Bakhtina Marina; Tsai Ming-Daw
Mismatched and matched dNTP incorporation by DNA polymerase beta proceed via analogous kinetic pathways.
Biochemistry 2008;47(37):9718-27.
2008: Tang Kuo-Hsiang; Tsai Ming-Daw
Structure and function of 2:1 DNA polymerase.DNA complexes.
Journal of cellular physiology 2008;216(2):315-20.
2008: Kumar Sandeep; Bakhtina Marina; Tsai Ming-Daw
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus.
Biochemistry 2008;47(30):7875-87.
2008: Lee Hyun; Yuan Chunhua; Hammet Andrew; Mahajan Anjali; Chen Eric S-W; Wu Ming-Ru; Su Mei-I; Heierhorst Jörg; Tsai Ming-Daw
Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.
Molecular cell 2008;30(6):767-78.
2008: Tang Kuo-Hsiang; Niebuhr Marc; Tung Chang-Shung; Chan Hsiu-Chien; Chou Chia-Cheng; Tsai Ming-Daw
Mismatched dNTP incorporation by DNA polymerase beta does not proceed via globally different conformational pathways.
Nucleic acids research 2008;36(9):2948-57.
2008: Tu Shengjiang; Teng Yu-Ching; Yuan Chunhua; Wu Ying-Ta; Chan Meng-Yu; Cheng An-Ning; Lin Po-Hsun; Juan Li-Jung; Tsai Ming-Daw
The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif.
Nature structural & molecular biology 2008;15(4):419-21.
2008: Tang Kuo-Hsiang; Niebuhr Marc; Aulabaugh Ann; Tsai Ming-Daw
Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering.
Nucleic acids research 2008;36(3):849-60.
2008: Mahajan Anjali; Yuan Chunhua; Lee Hyun; Chen Eric S-W; Wu Pei-Yu; Tsai Ming-Daw
Structure and function of the phosphothreonine-specific FHA domain.
Science signaling 2008;1(51):re12.
2007: Vadysirisack Douangsone D; Chen Eric S-W; Zhang Zhaoxia; Tsai Ming-Daw; Chang Geen-Dong; Jhiang Sissy M
Identification of in vivo phosphorylation sites and their functional significance in the sodium iodide symporter.
The Journal of biological chemistry 2007;282(51):36820-8.
2007: Li Yi-Shan; Ho Jin-Yuan; Huang Chia-Chi; Lyu Syue-Yi; Lee Chun-Yen; Huang Yu-Ting; Wu Chang-Jer; Chan Hsiu-Chien; Huang Chuan-Jiuan; Hsu Ning-Shian; Tsai Ming-Daw; Li Tsung-Lin
A unique flavin mononucleotide-linked primary alcohol oxidase for glycopeptide A40926 maturation.
Journal of the American Chemical Society 2007;129(44):13384-5.
2007: Mahajan Anjali; Guo Yi; Yuan Chunhua; Weghorst Christopher M; Tsai Ming-Daw; Li Junan
Dissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16.
Journal of molecular biology 2007;373(4):990-1005.
2007: Tang Kuo-Hsiang; Guo Hongjie; Yi Wen; Tsai Ming-Daw; Wang Peng George
Investigation of the conformational states of Wzz and the Wzz.O-antigen complex under near-physiological conditions.
Biochemistry 2007;46(42):11744-52.
2007: Lin Y-C; Diccianni M B; Kim Y; Lin H-H; Lee C-H; Lin R-J; Joo S H; Li J; Chuang T-J; Yang A-S; Kuo H-H; Tsai M-D; Yu A L
Human p16gamma, a novel transcriptional variant of p16(INK4A), coexpresses with p16(INK4A) in cancer cells and inhibits cell-cycle progression.
Oncogene 2007;26(49):7017-27.
2007: Bakhtina Marina; Roettger Michelle P; Kumar Sandeep; Tsai Ming-Daw
A unified kinetic mechanism applicable to multiple DNA polymerases.
Biochemistry 2007;46(18):5463-72.
2007: Wang Yu; Lamarche Brandon J; Tsai Ming-Daw
Human DNA ligase IV and the ligase IV/XRCC4 complex: analysis of nick ligation fidelity.
Biochemistry 2007;46(17):4962-76.
2007: Tu Shengjiang; Bulloch Esther M M; Yang Lanhao; Ren Chen; Huang Wei-Chieh; Hsu Pang-Hung; Chen Chein-Hung; Liao Chung-Lin; Yu Hui-Ming; Lo Wan-Sheng; Freitas Michael A; Tsai Ming-Daw
Identification of histone demethylases in Saccharomyces cerevisiae.
The Journal of biological chemistry 2007;282(19):14262-71.
2007: Kumar Sandeep; Lamarche Brandon J; Tsai Ming-Daw
Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus.
Biochemistry 2007;46(12):3814-25.
2006: Li Junan; Mahajan Anjali; Tsai Ming-Daw
Ankyrin repeat: a unique motif mediating protein-protein interactions.
Biochemistry 2006;45(51):15168-78.
2006: Lamarche Brandon J; Kumar Sandeep; Tsai Ming-Daw
ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts.
Biochemistry 2006;45(49):14826-33.
2006: Ho Jin-Yuan; Huang Yu-Ting; Wu Chang-Jer; Li Yi-Shan; Tsai Ming-Daw; Li Tsung-Lin
Glycopeptide biosynthesis: Dbv21/Orf2 from dbv/tcp gene clusters are N-Ac-Glm teicoplanin pseudoaglycone deacetylases and Orf15 from cep gene cluster is a Glc-1-P thymidyltransferase.
Journal of the American Chemical Society 2006;128(42):13694-5.
2006: Sekar K; Yogavel M; Kanaujia Shankar Prasad; Sharma Alok; Velmurugan D; Poi M-J; Dauter Z; Tsai M-D
Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A2.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 7):717-24.
2006: Sekar K; Gayathri D; Velmurugan D; Jeyakanthan J; Yamane T; Poi M J; Tsai M D
Third calcium ion found in an inhibitor-bound phospholipase A2.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 4):392-7.
2006: Lamarche Brandon J; Tsai Ming-Daw
Contributions of an endonuclease IV homologue to DNA repair in the African swine fever virus.
Biochemistry 2006;45(9):2790-803.
2006: Showalter Alexander K; Lamarche Brandon J; Bakhtina Marina; Su Mei-I; Tang Kuo-Hsiang; Tsai Ming-Daw
Mechanistic comparison of high-fidelity and error-prone DNA polymerases and ligases involved in DNA repair.
Chemical reviews 2006;106(2):340-60.
2006: Sekar K; Yogavel M; Gayathri D; Velmurugan D; Krishna R; Poi M-J; Dauter Z; Dauter M; Tsai M-D
Atomic resolution structure of the double mutant (K53,56M) of bovine pancreatic phospholipase A2.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 1):1-5.
2005: Byeon In-Ja L; Li Hongyuan; Song Haiyan; Gronenborn Angela M; Tsai Ming-Daw
Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.
Nature structural & molecular biology 2005;12(11):987-93.
2005: Mahajan Anjali; Yuan Chunhua; Pike Brietta L; Heierhorst Jörg; Chang Chi-Fon; Tsai Ming-Daw
FHA domain-ligand interactions: importance of integrating chemical and biological approaches.
Journal of the American Chemical Society 2005;127(42):14572-3.
2005: Li Junan; Muscarella Peter; Joo Sang Hoon; Knobloch Thomas J; Melvin W Scott; Weghorst Christopher M; Tsai Ming-Daw
Dissection of CDK4-binding and transactivation activities of p34(SEI-1) and comparison between functions of p34(SEI-1) and p16(INK4A).
Biochemistry 2005;44(40):13246-56.
2005: Apiyo David; Zhao Li; Tsai Ming-Daw; Selby Thomas L
X-ray structure of the R69D phosphatidylinositol-specific phospholipase C enzyme: insight into the role of calcium and surrounding amino acids in active site geometry and catalysis.
Biochemistry 2005;44(30):9980-9.
2005: Lamarche Brandon J; Showalter Alexander K; Tsai Ming-Daw
An error-prone viral DNA ligase.
Biochemistry 2005;44(23):8408-17.
2005: Bakhtina Marina; Lee Soojin; Wang Yu; Dunlap Chris; Lamarche Brandon; Tsai Ming-Daw
Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta.
Biochemistry 2005;44(13):5177-87.
2005: Yuan Chunhua; Tu Shengjiang; Gelb Michael H; Tsai Ming-Daw
Unusual four-bond secondary H/D isotope effect supports a short-strong hydrogen bond between phospholipase A2 and a transition state analogue inhibitor.
Biochemistry 2005;44(12):4748-54.
2005: Sekar K; Rajakannan V; Gayathri D; Velmurugan D; Poi M-J; Dauter M; Dauter Z; Tsai M-D
Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):3-7.
2004: Yuan Chunhua; Li Junan; Mahajan Anjali; Poi Ming Jye; Byeon In-Ja L; Tsai Ming-Daw
Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship.
Biochemistry 2004;43(38):12152-61.
2004: Zhao Li; Liao Hua; Tsai Ming-Daw
The catalytic role of aspartate in a short strong hydrogen bond of the Asp274-His32 catalytic dyad in phosphatidylinositol-specific phospholipase C can be substituted by a chloride ion.
The Journal of biological chemistry 2004;279(31):31995-2000.
2004: Li Junan; Melvin W Scott; Tsai Ming-Daw; Muscarella Peter
The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner.
Biochemistry 2004;43(14):4394-9.
2004: Yongkiettrakul Suganya; Byeon In-Ja L; Tsai Ming-Daw
The ligand specificity of yeast Rad53 FHA domains at the +3 position is determined by nonconserved residues.
Biochemistry 2004;43(13):3862-9.
2004: Pike Brietta L; Yongkiettrakul Suganya; Tsai Ming-Daw; Heierhorst Jörg
Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae.
Molecular and cellular biology 2004;24(7):2779-88.
2004: Li Junan; Weghorst Christopher M; Tsutsumi Masahiro; Poi Ming J; Knobloch Thomas J; Casto Bruce C; Melvin W Scott; Tsai Ming-Daw; Muscarella Peter
Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumors.
Carcinogenesis 2004;25(2):263-8.
2004: Li Hongyuan; Byeon In Ja L; Ju Yong; Tsai Ming Daw
Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions.
Journal of molecular biology 2004;335(1):371-81.
2004: O'Maille Paul E; Tsai Ming-Daw; Greenhagen Bryan T; Chappell Joseph; Noel Joseph P
Gene library synthesis by structure-based combinatorial protein engineering.
Methods in enzymology 2004;388():75-91.
2003: Qin Dongyan; Lee Hyun; Yuan Chunhua; Ju Yong; Tsai Ming-Daw
Identification of potential binding sites for the FHA domain of human Chk2 by in vitro binding studies.
Biochemical and biophysical research communications 2003;311(4):803-8.
2003: Li Junan; Joo Sang Hoon; Tsai Ming-Daw
An NF-kappaB-specific inhibitor, IkappaBalpha, binds to and inhibits cyclin-dependent kinase 4.
Biochemistry 2003;42(46):13476-83.
2003: Sekar K; Vaijayanthi Mala S; Yogavel M; Velmurugan D; Poi Ming-Jye; Vishwanath B S; Gowda T V; Jeyaprakash A Arokia; Tsai M-D
Crystal structures of the free and anisic acid bound triple mutant of phospholipase A2.
Journal of molecular biology 2003;333(2):367-76.
2003: Pike Brietta L; Yongkiettrakul Suganya; Tsai Ming-Daw; Heierhorst Jörg
Diverse but overlapping functions of the two forkhead-associated (FHA) domains in Rad53 checkpoint kinase activation.
The Journal of biological chemistry 2003;278(33):30421-4.
2003: Poi Ming Jye; Tomaszewski John W; Yuan Chunhua; Dunlap Christopher A; Andersen Niels H; Gelb Michael H; Tsai Ming-Daw
A low-barrier hydrogen bond between histidine of secreted phospholipase A2 and a transition state analog inhibitor.
Journal of molecular biology 2003;329(5):997-1009.
2003: Li Junan; Li Hongyuan; Tsai Ming-Daw
Direct binding of the N-terminus of HTLV-1 tax oncoprotein to cyclin-dependent kinase 4 is a dominant path to stimulate the kinase activity.
Biochemistry 2003;42(22):6921-8.
2003: Yu Bao-Zhu; Apitz-Castro Rafael; Tsai Ming-Daw; Jain Mahendra K
Interaction of monodisperse anionic amphiphiles with the i-face of secreted phospholipase A2.
Biochemistry 2003;42(20):6293-301.
2003: Li Junan; Qin Dongyan; Knobloch Thomas J; Tsai Ming-Daw; Weghorst Christopher M; Melvin W Scott; Muscarella Peter
Expression and characterization of Syrian golden hamster p16, a homologue of human tumor suppressor p16 INK4A.
Biochemical and biophysical research communications 2003;304(2):241-7.
2003: Mihai Cornelia; Kravchuk Alexander V; Tsai Ming-Daw; Bruzik Karol S
Application of Brønsted-type LFER in the study of the phospholipase C mechanism.
Journal of the American Chemical Society 2003;125(11):3236-42.
2003: Kravchuk Alexander V; Zhao Li; Bruzik Karol S; Tsai Ming-Daw
Engineering a catalytic metal binding site into a calcium-independent phosphatidylinositol-specific phospholipase C leads to enhanced stereoselectivity.
Biochemistry 2003;42(8):2422-30.
2003: Zhao Li; Liu Yinghui; Bruzik Karol S; Tsai Ming-Daw
A novel calcium-dependent bacterial phosphatidylinositol-specific phospholipase C displaying unprecedented magnitudes of thio effect, inverse thio effect, and stereoselectivity.
Journal of the American Chemical Society 2003;125(1):22-3.
2002: Rajakannan V; Yogavel M; Poi Ming-Jye; Jeyaprakash A Arockia; Jeyakanthan J; Velmurugan D; Tsai Ming-Daw; Sekar K
Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2.
Journal of molecular biology 2002;324(4):755-62.
2002: Dunlap Christopher A; Tsai Ming-Daw
Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta.
Biochemistry 2002;41(37):11226-35.
2002: O'Maille Paul E; Bakhtina Marina; Tsai Ming-Daw
Structure-based combinatorial protein engineering (SCOPE).
Journal of molecular biology 2002;321(4):677-91.
2002: Showalter Alexander K; Tsai Ming-Daw
A reexamination of the nucleotide incorporation fidelity of DNA polymerases.
Biochemistry 2002;41(34):10571-6.
2002: Tsai Ming Daw
FHA: a signal transduction domain with diverse specificity and function.
Structure (London, England : 1993) 2002;10(7):887-8.
2002: Li Junan; Tsai Ming-Daw
Novel insights into the INK4-CDK4/6-Rb pathway: counter action of gankyrin against INK4 proteins regulates the CDK4-mediated phosphorylation of Rb.
Biochemistry 2002;41(12):3977-83.
2001: Byeon I J; Yongkiettrakul S; Tsai M D
Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
Journal of molecular biology 2001;314(3):577-88.
2001: Yuan C; Yongkiettrakul S; Byeon I J; Zhou S; Tsai M D
Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
Journal of molecular biology 2001;314(3):563-75.
2001: Showalter A K; Byeon I J; Su M I; Tsai M D
Solution structure of a viral DNA polymerase X and evidence for a mutagenic function.
Nature structural biology 2001;8(11):942-6.
2001: Liu J; Tsai M D
DNA polymerase beta: pre-steady-state kinetic analyses of dATP alpha S stereoselectivity and alteration of the stereoselectivity by various metal ions and by site-directed mutagenesis.
Biochemistry 2001;40(30):9014-22.
2001: Kravchuk A V; Zhao L; Kubiak R J; Bruzik K S; Tsai M D
Mechanism of phosphatidylinositol-specific phospholipase C: origin of unusually high nonbridging thio effects.
Biochemistry 2001;40(18):5433-9.
2001: Kubiak R J; Yue X; Hondal R J; Mihai C; Tsai M D; Bruzik K S
Involvement of the Arg-Asp-His catalytic triad in enzymatic cleavage of the phosphodiester bond.
Biochemistry 2001;40(18):5422-32.
2001: Arndt J W; Gong W; Zhong X; Showalter A K; Liu J; Dunlap C A; Lin Z; Paxson C; Tsai M D; Chan M K
Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes.
Biochemistry 2001;40(18):5368-75.
2001: Showalter A K; Tsai M D
A DNA polymerase with specificity for five base pairs.
Journal of the American Chemical Society 2001;123(8):1776-7.
2001: Poi M J; Yen T; Li J; Song H; Lang J C; Schuller D E; Pearl D K; Casto B C; Tsai M D; Weghorst C M
Somatic INK4a-ARF locus mutations: a significant mechanism of gene inactivation in squamous cell carcinomas of the head and neck.
Molecular carcinogenesis 2001;30(1):26-36.
2000: Liao H; Yuan C; Su M I; Yongkiettrakul S; Qin D; Li H; Byeon I J; Pei D; Tsai M D
Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9.
Journal of molecular biology 2000;304(5):941-51.
2000: Kraynov V S; Showalter A K; Liu J; Zhong X; Tsai M D
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity.
Biochemistry 2000;39(51):16008-15.
2000: Yu B Z; Poi M J; Ramagopal U A; Jain R; Ramakumar S; Berg O G; Tsai M D; Sekar K; Jain M K
Structural basis of the anionic interface preference and kcat* activation of pancreatic phospholipase A2.
Biochemistry 2000;39(40):12312-23.
2000: Wang P; Byeon I J; Liao H; Beebe K D; Yongkiettrakul S; Pei D; Tsai M D
II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
Journal of molecular biology 2000;302(4):927-40.
2000: Yuan C; Selby T L; Li J; Byeon I J; Tsai M D
Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data.
Protein science : a publication of the Protein Society 2000;9(6):1120-8.
2000: Li J; Poi M J; Qin D; Selby T L; Byeon I J; Tsai M D
Tumor suppressor INK4: quantitative structure-function analyses of p18INK4C as an inhibitor of cyclin-dependent kinase 4.
Biochemistry 2000;39(4):649-57.
1999: Liao H; Byeon I J; Tsai M D
Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53.
Journal of molecular biology 1999;294(4):1041-9.
1999: Yuan C; Li J; Selby T L; Byeon I J; Tsai M D
Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C).
Journal of molecular biology 1999;294(1):201-11.
1999: Yu B Z; Rogers J; Tsai M D; Pidgeon C; Jain M K
Contributions of residues of pancreatic phospholipase A2 to interfacial binding, catalysis, and activation.
Biochemistry 1999;38(15):4875-84.
1999: Li J; Byeon I J; Ericson K; Poi M J; O'Maille P; Selby T; Tsai M D
Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A.
Biochemistry 1999;38(10):2930-40.
1999: Yuan C; Byeon I J; Poi M J; Tsai M D
Structural analysis of phospholipase A2 from functional perspective. 2. Characterization of a molten globule-like state induced by site-specific mutagenesis.
Biochemistry 1999;38(10):2919-29.
1999: Yuan C; Byeon I J; Li Y; Tsai M D
Structural analysis of phospholipase A2 from functional perspective. 1. Functionally relevant solution structure and roles of the hydrogen-bonding network.
Biochemistry 1999;38(10):2909-18.
1998: Rogers J; Yu B Z; Tsai M D; Berg O G; Jain M K
Cationic residues 53 and 56 control the anion-induced interfacial k*cat activation of pancreatic phospholipase A2.
Biochemistry 1998;37(26):9549-56.
1998: Sekar K; Sekharudu C; Tsai M D; Sundaralingam M
1.72 A resolution refinement of the trigonal form of bovine pancreatic phospholipase A2.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 3):342-6.
1998: Sekar K; Kumar A; Liu X; Tsai M D; Gelb M H; Sundaralingam M
Structure of the complex of bovine pancreatic phospholipase A2 with a transition-state analogue.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 3):334-41.
1998: Ahn J; Kraynov V S; Zhong X; Werneburg B G; Tsai M D
DNA polymerase beta: effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes.
The Biochemical journal 1998;331 ( Pt 1)():79-87.
1998: Hondal R J; Zhao Z; Kravchuk A V; Liao H; Riddle S R; Yue X; Bruzik K S; Tsai M D
Mechanism of phosphatidylinositol-specific phospholipase C: a unified view of the mechanism of catalysis.
Biochemistry 1998;37(13):4568-80.
1998: Byeon I J; Li J; Ericson K; Selby T L; Tevelev A; Kim H J; O'Maille P; Tsai M D
Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4.
Molecular cell 1998;1(3):421-31.
1997: Zhong X; Patel S S; Werneburg B G; Tsai M D
DNA polymerase beta: multiple conformational changes in the mechanism of catalysis.
Biochemistry 1997;36(39):11891-900.
1997: Hondal R J; Riddle S R; Kravchuk A V; Zhao Z; Liao H; Bruzik K S; Tsai M D
Phosphatidylinositol-specific phospholipase C: kinetic and stereochemical evidence for an interaction between arginine-69 and the phosphate group of phosphatidylinositol.
Biochemistry 1997;36(22):6633-42.
1997: Kraynov V S; Werneburg B G; Zhong X; Lee H; Ahn J; Tsai M D
DNA polymerase beta: analysis of the contributions of tyrosine-271 and asparagine-279 to substrate specificity and fidelity of DNA replication by pre-steady-state kinetics.
The Biochemical journal 1997;323 ( Pt 1)():103-11.
1997: Sekar K; Yu B Z; Rogers J; Lutton J; Liu X; Chen X; Tsai M D; Jain M K; Sundaralingam M
Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99.
Biochemistry 1997;36(11):3104-14.
1997: Ahn J; Werneburg B G; Tsai M D
DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant.
Biochemistry 1997;36(5):1100-7.
1996: Huang B; Yu B Z; Rogers J; Byeon I J; Sekar K; Chen X; Sundaralingam M; Tsai M D; Jain M K
Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface.
Biochemistry 1996;35(37):12164-74.
1996: Tevelev A; Byeon I J; Selby T; Ericson K; Kim H J; Kraynov V; Tsai M D
Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism.
Biochemistry 1996;35(29):9475-87.
1996: Werneburg B G; Ahn J; Zhong X; Hondal R J; Kraynov V S; Tsai M D
DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity.
Biochemistry 1996;35(22):7041-50.
1996: Tzeng M C; Yen C H; Tsai M D
Binding proteins on synaptic membranes for certain phospholipases A2 with presynaptic toxicity.
Advances in experimental medicine and biology 1996;391():271-8.
1995: Zhu H; Dupureur C M; Zhang X; Tsai M D
Phospholipase A2 engineering. The roles of disulfide bonds in structure, conformational stability, and catalytic function.
Biochemistry 1995;34(46):15307-14.
1995: Liu X; Zhu H; Huang B; Rogers J; Yu B Z; Kumar A; Jain M K; Sundaralingam M; Tsai M D
Phospholipase A2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMR.
Biochemistry 1995;34(22):7322-34.
1995: Tzeng M C; Yen C H; Hseu M J; Tseng C C; Tsai M D; Dupureur C M
Binding proteins on synaptic membranes for crotoxin and taipoxin, two phospholipases A2 with neurotoxicity.
Toxicon : official journal of the International Society on Toxinology 1995;33(4):451-7.
1995: Byeon L; Shi Z; Tsai M D
Mechanism of adenylate kinase. The "essential lysine" helps to orient the phosphates and the active site residues to proper conformations.
Biochemistry 1995;34(10):3172-82.
1995: Tzeng M C; Yen C H; Hseu M J; Dupureur C M; Tsai M D
Conversion of bovine pancreatic phospholipase A2 at a single site into a competitor of neurotoxic phospholipases A2 by site-directed mutagenesis.
The Journal of biological chemistry 1995;270(5):2120-3.
1995: Conrad S F; Byeon I J; DiGeorge A M; Lairmore M D; Tsai M D; Kaumaya P T
Immunogenicity and conformational properties of an N-linked glycosylated peptide epitope of human T-lymphotropic virus type 1 (HTLV-I).
Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity 1995;1(2):83-92.
1995: Tsai M D; Jiang R T; Dahnke T; Shi Z
Manipulating phosphorus stereospecificity of adenylate kinase by site-directed mutagenesis.
Methods in enzymology 1995;249():425-43.
1994: Li Y; Yu B Z; Zhu H; Jain M K; Tsai M D
Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-49.
Biochemistry 1994;33(49):14714-22.
1994: Huang B; Shi Z; Tsai M D
A small, high-copy-number vector suitable for both in vitro and in vivo gene expression.
Gene 1994;151(1-2):143-5.
1994: Kumar A; Sekharudu C; Ramakrishnan B; Dupureur C M; Zhu H; Tsai M D; Sundaralingam M
Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water.
Protein science : a publication of the Protein Society 1994;3(11):2082-8.
1994: Bruzik K S; Hakeem A A; Tsai M D
Are D- and L-chiro-phosphoinositides substrates of phosphatidylinositol-specific phospholipase C?
Biochemistry 1994;33(27):8367-74.
1994: Dahnke T; Tsai M D
Mechanism of adenylate kinase. The conserved aspartates 140 and 141 are important for transition state stabilization instead of substrate-induced conformational changes.
The Journal of biological chemistry 1994;269(11):8075-81.
1994: Bruzik K S; Tsai M D
Toward the mechanism of phosphoinositide-specific phospholipases C.
Bioorganic & medicinal chemistry 1994;2(2):49-72.
1993: Byeon I J; Yan H; Edison A S; Mooberry E S; Abildgaard F; Markley J L; Tsai M D
Mechanism of adenylate kinase. 1H, 13C, and 15N NMR assignments, secondary structures, and substrate binding sites.
Biochemistry 1993;32(46):12508-21.
1993: Shi Z; Byeon I J; Jiang R T; Tsai M D
Mechanism of adenylate kinase. What can be learned from a mutant enzyme with minor perturbation in kinetic parameters?
Biochemistry 1993;32(25):6450-8.
1992: Sekharudu C; Ramakrishnan B; Huang B; Jiang R T; Dupureur C M; Tsai M D; Sundaralingam M
Crystal structure of the Y52F/Y73F double mutant of phospholipase A2: increased hydrophobic interactions of the phenyl groups compensate for the disrupted hydrogen bonds of the tyrosines.
Protein science : a publication of the Protein Society 1992;1(12):1585-94.
1992: Dupureur C M; Yu B Z; Mamone J A; Jain M K; Tsai M D
Phospholipase A2 engineering. The structural and functional roles of aromaticity and hydrophobicity in the conserved phenylalanine-22 and phenylalanine-106 aromatic sandwich.
Biochemistry 1992;31(43):10576-83.
1992: Jain M K; Yu B Z; Rogers J; Gelb M H; Tsai M D; Hendrickson E K; Hendrickson H S
Interfacial catalysis by phospholipase A2: the rate-limiting step for enzymatic turnover.
Biochemistry 1992;31(34):7841-7.
1992: Dupureur C M; Yu B Z; Jain M K; Noel J P; Deng T; Li Y; Byeon I J; Tsai M D
Phospholipase A2 engineering. Structural and functional roles of highly conserved active site residues tyrosine-52 and tyrosine-73.
Biochemistry 1992;31(28):6402-13.
1992: Dahnke T; Shi Z; Yan H; Jiang R T; Tsai M D
Mechanism of adenylate kinase. Structural and functional roles of the conserved arginine-97 and arginine-132.
Biochemistry 1992;31(27):6318-28.
1992: Bruzik K S; Morocho A M; Jhon D Y; Rhee S G; Tsai M D
Phospholipids chiral at phosphorus. Stereochemical mechanism for the formation of inositol 1-phosphate catalyzed by phosphatidylinositol-specific phospholipase C.
Biochemistry 1992;31(22):5183-93.
1991: Noel J P; Bingman C A; Deng T L; Dupureur C M; Hamilton K J; Jiang R T; Kwak J G; Sekharudu C; Sundaralingam M; Tsai M D
Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
Biochemistry 1991;30(51):11801-11.
1991: Tsai M D; Yan H G
Mechanism of adenylate kinase: site-directed mutagenesis versus X-ray and NMR.
Biochemistry 1991;30(28):6806-18.
1991: Yan H G; Tsai M D
Mechanism of adenylate kinase. Demonstration of a functional relationship between aspartate 93 and Mg2+ by site-directed mutagenesis and proton, phosphorus-31, and magnesium-25 NMR.
Biochemistry 1991;30(22):5539-46.
1991: Bruzik K S; Tsai M D
Phospholipase stereospecificity at phosphorus.
Methods in enzymology 1991;197():258-69.
1990: Loffredo W M; Jiang R T; Tsai M D
Phospholipids chiral at phosphorus. Dramatic effects of phosphorus chirality on the deuterium NMR properties of the choline head group of phospholipids in the liquid crystalline phase.
Biochemistry 1990;29(49):10912-8.
1990: Yan H G; Dahnke T; Zhou B B; Nakazawa A; Tsai M D
Mechanism of adenylate kinase. Critical evaluation of the X-ray model and assignment of the AMP site.
Biochemistry 1990;29(49):10956-64.
1990: Deng T L; Noel J P; Tsai M D
A novel expression vector for high-level synthesis and secretion of foreign proteins in Escherichia coli: overproduction of bovine pancreatic phospholipase A2.
Gene 1990;93(2):229-34.
1990: Yan H G; Shi Z T; Tsai M D
Mechanism of adenylate kinase. Structural and functional demonstration of arginine-138 as a key catalytic residue that cannot be replaced by lysine.
Biochemistry 1990;29(27):6385-92.
1990: Tian G C; Yan H G; Jiang R T; Kishi F; Nakazawa A; Tsai M D
Mechanism of adenylate kinase. Are the essential lysines essential?
Biochemistry 1990;29(18):4296-304.
1990: Lin G L; Bennett C F; Tsai M D
Phospholipids chiral at phosphorus. Stereochemical mechanism of reactions catalyzed by phosphatidylinositide-specific phospholipase C from Bacillus cereus and guinea pig uterus.
Biochemistry 1990;29(11):2747-57.
1989: Sanders C R; Tian G C; Tsai M D
Mechanism of adenylate kinase. Is there a relationship between local substrate dynamics, local binding energy, and the catalytic mechanism?
Biochemistry 1989;28(23):9028-43.
1989: Noel J P; Tsai M D
Phospholipase A2 engineering: design, synthesis, and expression of a gene for bovine (pro)phospholipase A2.
Journal of cellular biochemistry 1989;40(3):309-20.
1989: Sanders C R; Tsai M D
Ligand-protein interactions via nuclear magnetic resonance of quadrupolar nuclei.
Methods in enzymology 1989;177():317-33.
1988: Lin G; Noel J; Loffredo W; Stable H Z; Tsai M D
Use of short-chain cyclopentano-phosphatidylcholines to probe the mode of activation of phospholipase A2 from bovine pancreas and bee venom.
The Journal of biological chemistry 1988;263(26):13208-14.
1988: Tian G C; Sanders C R; Kishi F; Nakazawa A; Tsai M D
Mechanism of adenylate kinase. Histidine-36 is not directly involved in catalysis, but protects cysteine-25 and stabilizes the tertiary structure.
Biochemistry 1988;27(15):5544-52.
1988: Sarvis H E; Loffredo W; Dluhy R A; Hernqvist L; Wisner D A; Tsai M D
Phospholipids chiral at phosphorus. Characterization of the sub-gel phase of thiophosphatidylcholines by use of X-ray diffraction, phosphorus-31 nuclear magnetic resonance, and Fourier transform infrared spectroscopy.
Biochemistry 1988;27(13):4625-31.
1988: Rosario-Jansen T; Jiang R T; Tsai M D; Hanahan D J
Phospholipids chiral at phosphorus. Synthesis and stereospecificity of phosphorothioate analogues of platelet-activating factor.
Biochemistry 1988;27(13):4619-24.
1987: Shyy Y J; Tian G; Tsai M D
Mechanism of adenylate kinase. Does adenosine 5'-triphosphate bind to the adenosine 5'-monophosphate site?
Biochemistry 1987;26(20):6411-5.
1987: Bruzik K S; Tsai M D
A calorimetric study of the thermotropic behavior of pure sphingomyelin diastereomers.
Biochemistry 1987;26(17):5364-8.
1987: Raetz C R; Carman G M; Dowhan W; Jiang R T; Waszkuc W; Loffredo W; Tsai M D
Phospholipids chiral at phosphorus. Steric course of the reactions catalyzed by phosphatidylserine synthase from Escherichia coli and yeast.
Biochemistry 1987;26(13):4022-7.
1985: Tsai T C; Hart J; Jiang R T; Bruzik K; Tsai M D
Phospholipids chiral at phosphorus. Use of chiral thiophosphatidylcholine to study the metal-binding properties of bee venom phospholipase A2.
Biochemistry 1985;24(13):3180-8.
1984: Tsai T C; Jiang R T; Tsai M D
Phospholipids chiral at phosphorus. Properties of small unilamellar vesicles of chiral thiophosphatidylcholine.
Biochemistry 1984;23(23):5564-70.
1984: Jiang R T; Shyy Y J; Tsai M D
Phospholipids chiral at phosphorus. Absolute configuration of chiral thiophospholipids and stereospecificity of phospholipase D.
Biochemistry 1984;23(8):1661-7.
1984: Bruzik K; Tsai M D
Phospholipids chiral at phosphorus. Synthesis of chiral phosphatidylcholine and stereochemistry of phospholipase D.
Biochemistry 1984;23(8):1656-61.
1983: Bruzik K; Jiang R T; Tsai M D
Phospholipids chiral at phosphorus. Preparation and spectral properties of chiral thiophospholipids.
Biochemistry 1983;22(10):2478-86.

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