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Ming-Jer Tsai
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119
Tsai, Sophia
93
O'Malley, Bert
17
DeMayo, Francesco
11
Nawaz, Zafar
10
Qiu, Y
10
Cooney, Austin
9
Pereira, Fred
8
Xu, Jianming
8
Wong, Jiemin
7
Naya, FJ
7
Qin, Jun
7
Conneely, Orla
6
Onate, Sergio
6
Yan, Jun
6
Weigel, Nancy
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All Publications
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2009: McKenna Neil J; Cooney Austin J; DeMayo Francesco J; Downes Michael; Glass Christopher K; Lanz Rainer B; Lazar Mitchell A; Mangelsdorf David J; Moore David D; Qin Jun; Steffen David L; Tsai Ming-Jer; Tsai Sophia Y; Yu Ruth; Margolis Ronald N; Evans Ronald M; O'Malley Bert W
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.
Molecular endocrinology (Baltimore, Md.) 2009;23(6):740-6.
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2009: Kim Bum Jun; Takamoto Norio; Yan Jun; Tsai Sophia Y; Tsai Ming-Jer
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum.
Developmental biology 2009;326(2):378-91.
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2009: Li Luoping; Xie Xin; Qin Jun; Jeha George S; Saha Pradip K; Yan Jun; Haueter Claire M; Chan Lawrence; Tsai Sophia Y; Tsai Ming-Jer
The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism.
Cell metabolism 2009;9(1):77-87.
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2008: Kang Yun Kyoung; Schiff Rachel; Ko Lan; Wang Tao; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis.
Cancer research 2008;68(19):7887-96.
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2008: Li Chao; Liang Yao-Yun; Feng Xin-Hua; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover.
Molecular cell 2008;31(6):835-49.
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2008: Yan Jun; Erdem Halime; Li Rile; Cai Yi; Ayala Gustavo; Ittmann Michael; Yu-Lee Li-yuan; Tsai Sophia Y; Tsai Ming-Jer
Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression.
Cancer research 2008;68(13):5460-8.
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2008: Yi Ping; Feng Qin; Amazit Larbi; Lonard David M; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.
Molecular cell 2008;29(4):465-76.
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2008: Qin Jun; Tsai Ming-Jer; Tsai Sophia Y
Essential roles of COUP-TFII in Leydig cell differentiation and male fertility.
PloS one 2008;3(9):e3285.
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2007: Xia Anping; Visosky Ann Marie B; Cho Jang-Hyeon; Tsai Ming-Jer; Pereira Fred A; Oghalai John S
Altered traveling wave propagation and reduced endocochlear potential associated with cochlear dysplasia in the BETA2/NeuroD1 null mouse.
Journal of the Association for Research in Otolaryngology : JARO 2007;8(4):447-63.
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2007: Lin Fu-Jung; Tsai Ming-Jer; Tsai Sophia Y
Artery and vein formation: a tug of war between different forces.
EMBO reports 2007;8(10):920-4.
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2007: Kurihara Isao; Lee Dong-Kee; Petit Fabrice G; Jeong Jaewook; Lee Kevin; Lydon John P; DeMayo Francesco J; Tsai Ming-Jer; Tsai Sophia Y
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity.
PLoS genetics 2007;3(6):e102.
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2007: Han Sang Jun; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice.
Endocrinology 2007;148(5):2471-86.
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2007: Petit Fabrice G; Jamin Soazik P; Kurihara Isao; Behringer Richard R; DeMayo Francesco J; Tsai Ming-Jer; Tsai Sophia Y
Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiency.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6293-8.
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2007: Qin Jun; Suh Jae Mi; Kim Bum-Jun; Yu Cheng-Tai; Tanaka Toshiya; Kodama Tatsuhiko; Tsai Ming-Jer; Tsai Sophia Y
The expression pattern of nuclear receptors during cerebellar development.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(3):810-20.
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2007: Li Chao; Wu Ray-Chang; Amazit Larbi; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover.
Molecular and cellular biology 2007;27(4):1296-308.
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2006: Lee K; Jeong J; Tsai M-J; Tsai S; Lydon J P; DeMayo F J
Molecular mechanisms involved in progesterone receptor regulation of uterine function.
The Journal of steroid biochemistry and molecular biology 2006;102(1-5):41-50.
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2006: Suh Jae Mi; Yu Cheng-Tai; Tang Ke; Tanaka Toshiya; Kodama Tatsuhiko; Tsai Ming-Jer; Tsai Sophia Y
The expression profiles of nuclear receptors in the developing and adult kidney.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3412-20.
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2006: Yan Jun; Yu Cheng-Tai; Ozen Mustafa; Ittmann Michael; Tsai Sophia Y; Tsai Ming-Jer
Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway.
Cancer research 2006;66(22):11039-46.
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2006: Louet Jean-Francois; Coste Agnès; Amazit Larbi; Tannour-Louet Mounia; Wu Ray-Chang; Tsai Sophia Y; Tsai Ming-Jer; Auwerx Johan; O'Malley Bert W
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17868-73.
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2006: Lee Kevin; Jeong JaeWook; Kwak Inseok; Yu Cheng-Tai; Lanske Beate; Soegiarto Desi W; Toftgard Rune; Tsai Ming-Jer; Tsai Sophia; Lydon John P; DeMayo Francesco J
Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus.
Nature genetics 2006;38(10):1204-9.
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2006: Le May Cedric; Chu Khoi; Hu Min; Ortega Christina S; Simpson Evan R; Korach Kenneth S; Tsai Ming-Jer; Mauvais-Jarvis Franck
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9232-7.
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2006: Yan Jun; Tsai Sophia Y; Tsai Ming-Jer
SRC-3/AIB1: transcriptional coactivator in oncogenesis.
Acta pharmacologica Sinica 2006;27(4):387-94.
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2006: Cho Jang-Hyeon; Tsai Ming-Jer
Preferential posterior cerebellum defect in BETA2/NeuroD1 knockout mice is the result of differential expression of BETA2/NeuroD1 along anterior-posterior axis.
Developmental biology 2006;290(1):125-38.
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2006: Li Xiaotao; Lonard David M; Jung Sung Yun; Malovannaya Anna; Feng Qin; Qin Jun; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome.
Cell 2006;124(2):381-92.
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2006: Han Sang Jun; DeMayo Francesco J; Xu Jianming; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor.
Molecular endocrinology (Baltimore, Md.) 2006;20(1):45-55.
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2006: Pennesi Mark E; Bramblett Debra E; Cho Jang-Hyeon; Tsai Ming-Jer; Wu Samuel M
A role for bHLH transcription factors in retinal degeneration and dysfunction.
Advances in experimental medicine and biology 2006;572():155-61.
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2005: You Li-Ru; Takamoto Norio; Yu Cheng-Tai; Tanaka Toshiya; Kodama Tatsuhiko; Demayo Francesco J; Tsai Sophia Y; Tsai Ming-Jer
Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16351-6.
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2005: Yi Ping; Wu Ray-Chang; Sandquist Joshua; Wong Jiemin; Tsai Sophia Y; Tsai Ming-Jer; Means Anthony R; O'Malley Bert W
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).
Molecular and cellular biology 2005;25(21):9687-99.
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2005: Zhou Hai-Jun; Yan Jun; Luo Weiping; Ayala Gustavo; Lin Sue-Hwa; Erdem Halime; Ittmann Michael; Tsai Sophia Y; Tsai Ming-Jer
SRC-3 is required for prostate cancer cell proliferation and survival.
Cancer research 2005;65(17):7976-83.
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2005: Han Sang Jun; Jeong Jaewook; Demayo Francesco J; Xu Jianming; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice.
Molecular and cellular biology 2005;25(18):8150-65.
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2005: Takamoto Norio; Kurihara Isao; Lee Kevin; Demayo Francesco J; Tsai Ming-Jer; Tsai Sophia Y
Haploinsufficiency of chicken ovalbumin upstream promoter transcription factor II in female reproduction.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2299-308.
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2005: Ye Xiangcang; Han Sang Jun; Tsai Sophia Y; DeMayo Francesco J; Xu Jianming; Tsai Ming-Jer; O'Malley Bert W
Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(27):9487-92.
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2005: You Li-Ru; Lin Fu-Jung; Lee Christopher T; DeMayo Francesco J; Tsai Ming-Jer; Tsai Sophia Y
Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity.
Nature 2005;435(7038):98-104.
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2005: Takamoto Norio; You Li-Ru; Moses Kelvin; Chiang Chin; Zimmer Warren E; Schwartz Robert J; DeMayo Francesco J; Tsai Ming-Jer; Tsai Sophia Y
COUP-TFII is essential for radial and anteroposterior patterning of the stomach.
Development (Cambridge, England) 2005;132(9):2179-89.
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2005: Tsai Ming-Jer; You Li-Ru; Tsai Sophia Y
Surprise in the Battle Field of Vein vs. Artery.
Organogenesis 2005;2(2):31-2.
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2005: Chu Khoi; Tsai Ming-Jer
Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion.
Diabetes 2005;54(4):1064-73.
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2004: Lee Christopher T; Li Luoping; Takamoto Norio; Martin James F; Demayo Francesco J; Tsai Ming-Jer; Tsai Sophia Y
The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development.
Molecular and cellular biology 2004;24(24):10835-43.
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2004: Petit Fabrice G; Salas Ramiro; Tsai Ming-Jer; Tsai Sophia Y
The regulation of COUP-TFII gene expression by Ets-1 is enhanced by the steroid receptor co-activators.
Mechanisms of ageing and development 2004;125(10-11):719-32.
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2004: Wu Ray-Chang; Qin Jun; Yi Ping; Wong Jiemin; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways.
Molecular cell 2004;15(6):937-49.
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2004: Bramblett Debra E; Pennesi Mark E; Wu Samuel M; Tsai Ming-Jer
The transcription factor Bhlhb4 is required for rod bipolar cell maturation.
Neuron 2004;43(6):779-93.
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2004: Cho Jang-Hyeon; Tsai Ming-Jer
The role of BETA2/NeuroD1 in the development of the nervous system.
Molecular neurobiology 2004;30(1):35-47.
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2004: Mark Manuel; Yoshida-Komiya Hiromi; Gehin Martine; Liao Lan; Tsai Ming-Jer; O'Malley Bert W; Chambon Pierre; Xu Jianming
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4453-8.
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2004: Yamaguchi Hideki; Zhou Cheng; Lin Song-Chang; Durand Beatrice; Tsai Sophia Y; Tsai Ming-Jer
The nuclear orphan receptor COUP-TFI is important for differentiation of oligodendrocytes.
Developmental biology 2004;266(2):238-51.
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2003: Zhou Ge; Hashimoto Yoshihiro; Kwak Inseok; Tsai Sophia Y; Tsai Ming-Jer
Role of the steroid receptor coactivator SRC-3 in cell growth.
Molecular and cellular biology 2003;23(21):7742-55.
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2003: Park Joo-In; Tsai Sophia Y; Tsai Ming-Jer
Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions.
The Keio journal of medicine 2003;52(3):174-81.
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2003: Li Xiaotao; Wong Jiemin; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification.
Molecular and cellular biology 2003;23(11):3763-73.
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2003: Ngan Elly S W; Hashimoto Yoshihiro; Ma Zhi-Qing; Tsai Ming-Jer; Tsai Sophia Y
Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer.
Oncogene 2003;22(5):734-9.
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2003: Moates J Michael; Nanda Sarmistha; Cissell Michelle A; Tsai Ming-Jer; Stein Roland
BETA2 activates transcription from the upstream glucokinase gene promoter in islet beta-cells and gut endocrine cells.
Diabetes 2003;52(2):403-8.
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2003: Pennesi Mark E; Cho Jang-Hyeon; Yang Zhuo; Wu Schonmei H; Zhang Jian; Wu Samuel M; Tsai Ming-Jer
BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(2):453-61.
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2003: Zhou Hai-Jun; Tsai Sophia Y; Tsai Ming-Jer
RNAi technology and its use in studying the function of nuclear receptors and coregulators.
Nuclear receptor signaling 2003;1():e008.
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2003: Nemoz-Gaillard Eric; Tsai Ming-Jer; Tsai Sophia Y
Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.
Nuclear receptor signaling 2003;1():e005.
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2002: Liu Zheng; Auboeuf Didier; Wong Jiemin; Chen J Don; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):7940-4.
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2002: Wu Ray-Chang; Qin Jun; Hashimoto Yoshihiro; Wong Jiemin; Xu Jianming; Tsai Sophia Y; Tsai Ming-Jer; O'Malley Bert W
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.
Molecular and cellular biology 2002;22(10):3549-61.
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2002: Huang Hsiang-po; Chu Khoi; Nemoz-Gaillard Eric; Elberg Dorit; Tsai Ming-Jer
Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice.
Molecular endocrinology (Baltimore, Md.) 2002;16(3):541-51.
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2002: Bramblett Debra E; Copeland Neal G; Jenkins Nancy A; Tsai Ming-Jer
BHLHB4 is a bHLH transcriptional regulator in pancreas and brain that marks the dimesencephalic boundary.
Genomics 2002;79(3):402-12.
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2002: Salas Ramiro; Petit Fabrice G; Pipaon Carlos; Tsai Ming-Jer; Tsai Sophia Y
Induction of chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI ) gene expression is mediated by ETS factor binding sites.
European journal of biochemistry / FEBS 2002;269(1):317-25.
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2001: Liu Z; Wong J; Tsai S Y; Tsai M J; O'Malley B W
Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12426-31.
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2001: Zhou C; Tsai S Y; Tsai M J
COUP-TFI: an intrinsic factor for early regionalization of the neocortex.
Genes & development 2001;15(16):2054-9.
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2001: Cooney A J; Lee C T; Lin S C; Tsai S Y; Tsai M J
Physiological function of the orphans GCNF and COUP-TF.
Trends in endocrinology and metabolism: TEM 2001;12(6):247-51.
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2001: Chu K; Nemoz-Gaillard E; Tsai M J
BETA2 and pancreatic islet development.
Recent progress in hormone research 2001;56():23-46.
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2000: Liu M; Pereira F A; Price S D; Chu M J; Shope C; Himes D; Eatock R A; Brownell W E; Lysakowski A; Tsai M J
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems.
Genes & development 2000;14(22):2839-54.
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2000: Pereira F A; Tsai M J; Tsai S Y
COUP-TF orphan nuclear receptors in development and differentiation.
Cellular and molecular life sciences : CMLS 2000;57(10):1388-98.
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2000: Huang H P; Liu M; El-Hodiri H M; Chu K; Jamrich M; Tsai M J
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.
Molecular and cellular biology 2000;20(9):3292-307.
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2000: Huang H P; Tsai M J
Transcription factors involved in pancreatic islet development.
Journal of biomedical science 2000;7(1):27-34.
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2000: Liu M; Pleasure S J; Collins A E; Noebels J L; Naya F J; Tsai M J; Lowenstein D H
Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):865-70.
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2000: Bramblett D E; Huang H P; Tsai M J
Pancreatic islet development.
Advances in pharmacology (San Diego, Calif.) 2000;47():255-315.
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1999: Zhou C; Qiu Y; Pereira F A; Crair M C; Tsai S Y; Tsai M J
The nuclear orphan receptor COUP-TFI is required for differentiation of subplate neurons and guidance of thalamocortical axons.
Neuron 1999;24(4):847-59.
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1999: Lu S; Tsai S Y; Tsai M J
Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells.
Endocrinology 1999;140(11):5054-9.
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1999: Liu Z; Wong J; Tsai S Y; Tsai M J; O'Malley B W
Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9485-90.
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1999: Ma Z Q; Tsai M J; Tsai S Y
Suppression of gene expression by tethering KRAB domain to promoter of ER target genes.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):155-63.
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1999: McKenna N J; Xu J; Nawaz Z; Tsai S Y; Tsai M J; O'Malley B W
Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):3-12.
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1999: Pereira F A; Qiu Y; Zhou G; Tsai M J; Tsai S Y
The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development.
Genes & development 1999;13(8):1037-49.
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1999: Lanz R B; McKenna N J; Onate S A; Albrecht U; Wong J; Tsai S Y; Tsai M J; O'Malley B W
A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex.
Cell 1999;97(1):17-27.
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1999: Pipaón C; Tsai S Y; Tsai M J
COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site.
Molecular and cellular biology 1999;19(4):2734-45.
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1999: Lu S; Liu M; Epner D E; Tsai S Y; Tsai M J
Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter.
Molecular endocrinology (Baltimore, Md.) 1999;13(3):376-84.
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1999: Nawaz Z; Lonard D M; Smith C L; Lev-Lehman E; Tsai S Y; Tsai M J; O'Malley B W
The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily.
Molecular and cellular biology 1999;19(2):1182-9.
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1998: McKenna N J; Nawaz Z; Tsai S Y; Tsai M J; O'Malley B W
Distinct steady-state nuclear receptor coregulator complexes exist in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11697-702.
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1998: Onate S A; Boonyaratanakornkit V; Spencer T E; Tsai S Y; Tsai M J; Edwards D P; O'Malley B W
The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors.
The Journal of biological chemistry 1998;273(20):12101-8.
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1998: Mutoh H; Naya F J; Tsai M J; Leiter A B
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells.
Genes & development 1998;12(6):820-30.
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1998: Xu J; Qiu Y; DeMayo F J; Tsai S Y; Tsai M J; O'Malley B W
Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.
Science (New York, N.Y.) 1998;279(5358):1922-5.
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1997: Krishnan V; Pereira F A; Qiu Y; Chen C H; Beachy P A; Tsai S Y; Tsai M J
Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase.
Science (New York, N.Y.) 1997;278(5345):1947-50.
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1997: Lu S; Tsai S Y; Tsai M J
Regulation of androgen-dependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CKI p16 genes.
Cancer research 1997;57(20):4511-6.
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1997: Naya F J; Huang H P; Qiu Y; Mutoh H; DeMayo F J; Leiter A B; Tsai M J
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice.
Genes & development 1997;11(18):2323-34.
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1997: Spencer T E; Jenster G; Burcin M M; Allis C D; Zhou J; Mizzen C A; McKenna N J; Onate S A; Tsai S Y; Tsai M J; O'Malley B W
Steroid receptor coactivator-1 is a histone acetyltransferase.
Nature 1997;389(6647):194-8.
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1997: Krishnan V; Elberg G; Tsai M J; Tsai S Y
Identification of a novel sonic hedgehog response element in the chicken ovalbumin upstream promoter-transcription factor II promoter.
Molecular endocrinology (Baltimore, Md.) 1997;11(10):1458-66.
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1997: Qiu Y; Pereira F A; DeMayo F J; Lydon J P; Tsai S Y; Tsai M J
Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization.
Genes & development 1997;11(15):1925-37.
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1997: Jenster G; Spencer T E; Burcin M M; Tsai S Y; Tsai M J; O'Malley B W
Steroid receptor induction of gene transcription: a two-step model.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):7879-84.
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1997: Shibata H; Nawaz Z; Tsai S Y; O'Malley B W; Tsai M J
Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT).
Molecular endocrinology (Baltimore, Md.) 1997;11(6):714-24.
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1997: Owerbach D; Naya F J; Tsai M J; Allander S V; Powell D R; Gabbay K H
Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35.
Diabetes 1997;46(6):1069-74.
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1997: Mutoh H; Fung B P; Naya F J; Tsai M J; Nishitani J; Leiter A B
The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3560-4.
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1997: Tsai S Y; Tsai M J
Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age.
Endocrine reviews 1997;18(2):229-40.
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1997: Stellrecht C M; DeMayo F J; Finegold M J; Tsai M J
Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice.
The Journal of biological chemistry 1997;272(6):3567-72.
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1997: Shibata H; Spencer T E; Oñate S A; Jenster G; Tsai S Y; Tsai M J; O'Malley B W
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.
Recent progress in hormone research 1997;52():141-64; discussion 164-5.
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1996: Kieback D G; Levi T; Kohlberger P; Fiedrich U; Press M F; Rosenthal H E; Möbus V J; Runnebaum I B; Tong X W; Tsai M J
Chicken ovalbumin upstream promoter--transcription factor (COUP-TF) expression in human endometrial cancer cell lines.
Anticancer research 1996;16(6B):3371-6.
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1996: Xu J; Nawaz Z; Tsai S Y; Tsai M J; O'Malley B W
The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12195-9.
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1996: Smith C L; Oñate S A; Tsai M J; O'Malley B W
CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):8884-8.
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1996: Leng X; Cooney A J; Tsai S Y; Tsai M J
Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression.
Molecular and cellular biology 1996;16(5):2332-40.
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1996: Peyton M; Stellrecht C M; Naya F J; Huang H P; Samora P J; Tsai M J
BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes.
Molecular and cellular biology 1996;16(2):626-33.
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1996: Qiu Y; Krishnan V; Pereira F A; Tsai S Y; Tsai M J
Chicken ovalbumin upstream promoter-transcription factors and their regulation.
The Journal of steroid biochemistry and molecular biology 1996;56(1-6 Spec No):81-5.
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1995: Nawaz Z; Tsai M J; O'Malley B W
Specific mutations in the ligand binding domain selectively abolish the silencing function of human thyroid hormone receptor beta.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11691-5.
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1995: Oñate S A; Tsai S Y; Tsai M J; O'Malley B W
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily.
Science (New York, N.Y.) 1995;270(5240):1354-7.
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1995: Burris T P; Nawaz Z; Tsai M J; O'Malley B W
A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid hormone and retinoic acid receptors.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9525-9.
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1995: Qiu Y; Krishnan V; Zeng Z; Gilbert D J; Copeland N G; Gibson L; Yang-Feng T; Jenkins N A; Tsai M J; Tsai S Y
Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.
Genomics 1995;29(1):240-6.
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1995: Shieh S Y; Stellrecht C M; Tsai M J
Molecular characterization of the rat insulin enhancer-binding complex 3b2. Cloning of a binding factor with putative helicase motifs.
The Journal of biological chemistry 1995;270(37):21503-8.
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1995: Pereira F A; Qiu Y; Tsai M J; Tsai S Y
Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis.
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):503-8.
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1995: Naya F J; Stellrecht C M; Tsai M J
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor.
Genes & development 1995;9(8):1009-19.
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1995: Baniahmad A; Leng X; Burris T P; Tsai S Y; Tsai M J; O'Malley B W
The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing.
Molecular and cellular biology 1995;15(1):76-86.
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1995: Leng X; Blanco J; Tsai S Y; Ozato K; O'Malley B W; Tsai M J
Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region.
Molecular and cellular biology 1995;15(1):255-63.
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1995: Baniahmad C; Nawaz Z; Baniahmad A; Gleeson M A; Tsai M J; O'Malley B W
Enhancement of human estrogen receptor activity by SPT6: a potential coactivator.
Molecular endocrinology (Baltimore, Md.) 1995;9(1):34-43.
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1994: Leng X; Blanco J; Tsai S Y; Ozato K; O'Malley B W; Tsai M J
Mechanisms for synergistic activation of thyroid hormone receptor and retinoid X receptor on different response elements.
The Journal of biological chemistry 1994;269(50):31436-42.
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1994: Nawaz Z; Baniahmad C; Burris T P; Stillman D J; O'Malley B W; Tsai M J
The yeast SIN3 gene product negatively regulates the activity of the human progesterone receptor and positively regulates the activities of GAL4 and the HAP1 activator.
Molecular & general genetics : MGG 1994;245(6):724-33.
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1994: Peyton M; Moss L G; Tsai M J
Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box.
The Journal of biological chemistry 1994;269(41):25936-41.
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1994: Beekman J M; Cooney A J; Elliston J F; Tsai S Y; Tsai M J
A rapid one-step method to purify baculovirus-expressed human estrogen receptor to be used in the analysis of the oxytocin promoter.
Gene 1994;146(2):285-9.
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1994: Zeng Z; Allan G F; Thaller C; Cooney A J; Tsai S Y; O'Malley B W; Tsai M J
Detection of potential ligands for nuclear receptors in cellular extracts.
Endocrinology 1994;135(1):248-52.
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1994: Qiu Y; Cooney A J; Kuratani S; DeMayo F J; Tsai S Y; Tsai M J
Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4451-5.
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1994: Lutz B; Kuratani S; Cooney A J; Wawersik S; Tsai S Y; Eichele G; Tsai M J
Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons.
Development (Cambridge, England) 1994;120(1):25-36.
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1994: Tsai M J; O'Malley B W
Molecular mechanisms of action of steroid/thyroid receptor superfamily members.
Annual review of biochemistry 1994;63():451-86.
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1993: Leng X; Tsai S Y; O'Malley B W; Tsai M J
Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor.
The Journal of steroid biochemistry and molecular biology 1993;46(6):643-61.
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1993: Baniahmad A; Ha I; Reinberg D; Tsai S; Tsai M J; O'Malley B W
Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8832-6.
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1993: Beekman J M; Allan G F; Tsai S Y; Tsai M J; O'Malley B W
Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain.
Molecular endocrinology (Baltimore, Md.) 1993;7(10):1266-74.
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1993: Ing N H; Beekman J M; Kessler D J; Murphy M; Jayaraman K; Zendegui J G; Hogan M E; O'Malley B W; Tsai M J
In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide.
Nucleic acids research 1993;21(12):2789-96.
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1993: Baniahmad A; Tsai M J
Mechanisms of transcriptional activation by steroid hormone receptors.
Journal of cellular biochemistry 1993;51(2):151-6.
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1993: Cooney A J; Leng X; Tsai S Y; O'Malley B W; Tsai M J
Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors.
The Journal of biological chemistry 1993;268(6):4152-60.
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1992: Allan G F; Tsai S Y; Tsai M J; O'Malley B W
Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11750-4.
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1992: Baniahmad A; Tsai S Y; O'Malley B W; Tsai M J
Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10633-7.
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1992: Ing N H; Beekman J M; Tsai S Y; Tsai M J; O'Malley B W
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).
The Journal of biological chemistry 1992;267(25):17617-23.
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1992: Allan G F; Leng X; Tsai S Y; Weigel N L; Edwards D P; Tsai M J; O'Malley B W
Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.
The Journal of biological chemistry 1992;267(27):19513-20.
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1992: Cooney A J; Tsai S Y; O'Malley B W; Tsai M J
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors.
Molecular and cellular biology 1992;12(9):4153-63.
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1992: Bagchi M K; Tsai M J; O'Malley B W; Tsai S Y
Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems.
Endocrine reviews 1992;13(3):525-35.
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1992: Vegeto E; Allan G F; Schrader W T; Tsai M J; McDonnell D P; O'Malley B W
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor.
Cell 1992;69(4):703-13.
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1992: Bagchi M K; Tsai S Y; Tsai M J; O'Malley B W
Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2664-8.
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1992: Elliston J F; Beekman J M; Tsai S Y; O'Malley B W; Tsai M J
Hormone activation of baculovirus expressed progesterone receptors.
The Journal of biological chemistry 1992;267(8):5193-8.
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1992: Lee J K; Tam J W; Tsai M J; Tsai S Y
Identification of cis- and trans-acting factors regulating the expression of the human insulin receptor gene.
The Journal of biological chemistry 1992;267(7):4638-45.
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1992: Pham T A; McDonnell D P; Tsai M J; O'Malley B W
Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes.
Biochemistry 1992;31(5):1570-8.
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1992: O'Malley B W; Tsai M J
Molecular pathways of steroid receptor action.
Biology of reproduction 1992;46(2):163-7.
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1992: Nawaz Z; Tsai M J; McDonnell D P; O'Malley B W
Identification of novel steroid-response elements.
Gene expression 1992;2(1):39-47.
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1991: Bagchi M K; Tsai S Y; Tsai M J; O'Malley B W
Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70.
Molecular and cellular biology 1991;11(10):4998-5004.
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1991: Shieh S Y; Tsai M J
Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene.
The Journal of biological chemistry 1991;266(25):16708-14.
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1991: Bradshaw M S; Tsai S Y; Leng X H; Dobson A D; Conneely O M; O'Malley B W; Tsai M J
Studies on the mechanism of functional cooperativity between progesterone and estrogen receptors.
The Journal of biological chemistry 1991;266(25):16684-90.
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1991: Cooney A J; Tsai S Y; O'Malley B W; Tsai M J
Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat.
Journal of virology 1991;65(6):2853-60.
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1991: Pham T A; Elliston J F; Nawaz Z; McDonnell D P; Tsai M J; O'Malley B W
Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3125-9.
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1991: Allan G F; Ing N H; Tsai S Y; Srinivasan G; Weigel N L; Thompson E B; Tsai M J; O'Malley B W
Synergism between steroid response and promoter elements during cell-free transcription.
The Journal of biological chemistry 1991;266(9):5905-10.
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1991: Allan G F; Tsai S Y; O'Malley B W; Tsai M J
Steroid hormone receptors and in vitro transcription.
BioEssays : news and reviews in molecular, cellular and developmental biology 1991;13(2):73-8.
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1991: Wang L H; Ing N H; Tsai S Y; O'Malley B W; Tsai M J
The COUP-TFs compose a family of functionally related transcription factors.
Gene expression 1991;1(3):207-16.
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1991: O'Malley B W; Tsai S Y; Bagchi M; Weigel N L; Schrader W T; Tsai M J
Molecular mechanism of action of a steroid hormone receptor.
Recent progress in hormone research 1991;47():1-24; discussion 24-6.
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1990: Ritchie H H; Wang L H; Tsai S; O'Malley B W; Tsai M J
COUP-TF gene: a structure unique for the steroid/thyroid receptor superfamily.
Nucleic acids research 1990;18(23):6857-62.
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1990: Elliston J F; Fawell S E; Klein-Hitpass L; Tsai S Y; Tsai M J; Parker M G; O'Malley B W
Mechanism of estrogen receptor-dependent transcription in a cell-free system.
Molecular and cellular biology 1990;10(12):6607-12.
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1990: Tsai S Y; Srinivasan G; Allan G F; Thompson E B; O'Malley B W; Tsai M J
Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro.
The Journal of biological chemistry 1990;265(28):17055-61.
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1990: Elliston J F; Tsai S Y; O'Malley B W; Tsai M J
Superactive estrogen receptors. Potent activators of gene expression.
The Journal of biological chemistry 1990;265(20):11517-21.
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1990: Bagchi M K; Tsai S Y; Tsai M J; O'Malley B W
Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription.
Nature 1990;345(6275):547-50.
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1990: Hwung Y P; Gu Y Z; Tsai M J
Cooperativity of sequence elements mediates tissue specificity of the rat insulin II gene.
Molecular and cellular biology 1990;10(4):1784-8.
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1990: Bagchi M K; Tsai S Y; Weigel N L; Tsai M J; O'Malley B W
Regulation of in vitro transcription by progesterone receptor. Characterization and kinetic studies.
The Journal of biological chemistry 1990;265(9):5129-34.
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1990: Klein-Hitpass L; Tsai S Y; Weigel N L; Allan G F; Riley D; Rodriguez R; Schrader W T; Tsai M J; O'Malley B W
The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex.
Cell 1990;60(2):247-57.
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1989: Pastorcic M; Bagchi M K; Tsai S Y; Tsai M J; O'Malley B W
Multiple protein binding sites within the ovalbumin gene 5'-flanking region: isolation and characterization of sequence-specific binding proteins.
Nucleic acids research 1989;17(16):6693-711.
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1989: Conneely O M; Kettelberger D M; Tsai M J; Schrader W T; O'Malley B W
The chicken progesterone receptor A and B isoforms are products of an alternate translation initiation event.
The Journal of biological chemistry 1989;264(24):14062-4.
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1989: Wang L H; Tsai S Y; Cook R G; Beattie W G; Tsai M J; O'Malley B W
COUP transcription factor is a member of the steroid receptor superfamily.
Nature 1989;340(6229):163-6.
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1989: Tsai S Y; Tsai M J; O'Malley B W
Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements.
Cell 1989;57(3):443-8.
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1989: Crowe D T; Tsai M J
Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells.
Molecular and cellular biology 1989;9(4):1784-9.
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1989: Dobson A D; Conneely O M; Beattie W; Maxwell B L; Mak P; Tsai M J; Schrader W T; O'Malley B W
Mutational analysis of the chicken progesterone receptor.
The Journal of biological chemistry 1989;264(7):4207-11.
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1989: Klein-Hitpass L; Tsai S Y; Greene G L; Clark J H; Tsai M J; O'Malley B W
Specific binding of estrogen receptor to the estrogen response element.
Molecular and cellular biology 1989;9(1):43-9.
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1988: Bagchi M K; Elliston J F; Tsai S Y; Edwards D P; Tsai M J; O'Malley B W
Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1221-9.
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1988: Bradshaw M S; Tsai M J; O'Malley B W
A steroid response element can function in the absence of a distal promoter.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1286-93.
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1988: Tsai S Y; Carlstedt-Duke J; Weigel N L; Dahlman K; Gustafsson J A; Tsai M J; O'Malley B W
Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation.
Cell 1988;55(2):361-9.
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1988: Conneely O M; Dobson A D; Carson M A; Maxwell B L; Tsai M J; Schrader W T; O'Malley B W
Structure-function relationships of the chicken progesterone receptor.
Biochemical Society transactions 1988;16(5):683-7.
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1988: Hwung Y P; Wang L H; Tsai S Y; Tsai M J
Differential binding of the chicken ovalbumin upstream promoter (COUP) transcription factor to two different promoters.
The Journal of biological chemistry 1988;263(26):13470-4.
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1988: Bradshaw M S; Tsai M J; O'Malley B W
A far upstream ovalbumin enhancer binds nuclear factor-1-like factor.
The Journal of biological chemistry 1988;263(17):8485-90.
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1988: Hwung Y P; Crowe D T; Wang L H; Tsai S Y; Tsai M J
The COUP transcription factor binds to an upstream promoter element of the rat insulin II gene.
Molecular and cellular biology 1988;8(5):2070-7.
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1988: Tsai M J; Tsai S Y; Klein-Hitpass L; Bagchi M; Elliston J F; Carlstedt-Duke J; Gustafsson J A; O'Malley B W
Cooperative interactions of steroid hormone receptors with their cognate response elements.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():829-33.
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1988: Wang L H; Tsai S Y; Wang H; Sagami I; Tsai M J; O'Malley B W
The studies of COUP transcription factor from HeLa cells: purification and partial characterization.
Progress in clinical and biological research 1988;284():37-51.
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1988: Crowe D T; Hwung Y P; Tsai S Y; Tsai M J
Characterization of the cis and trans elements essential for rat insulin II gene expression.
Progress in clinical and biological research 1988;284():211-24.
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1987: Huckaby C S; Conneely O M; Beattie W G; Dobson A D; Tsai M J; O'Malley B W
Structure of the chromosomal chicken progesterone receptor gene.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8380-4.
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1987: Bagchi M K; Tsai S Y; Tsai M J; O'Malley B W
Purification and characterization of chicken ovalbumin gene upstream promoter transcription factor from homologous oviduct cells.
Molecular and cellular biology 1987;7(12):4151-8.
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1987: Wang L H; Tsai S Y; Sagami I; Tsai M J; O'Malley B W
Purification and characterization of chicken ovalbumin upstream promoter transcription factor from HeLa cells.
The Journal of biological chemistry 1987;262(33):16080-6.
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1987: Carson M A; Tsai M J; Conneely O M; Maxwell B L; Clark J H; Dobson A D; Elbrecht A; Toft D O; Schrader W T; O'Malley B W
Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid.
Molecular endocrinology (Baltimore, Md.) 1987;1(11):791-801.
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1987: Scott M J; Tsai M J; O'Malley B W
Deoxyribonuclease I sensitivity of the ovomucoid-ovoinhibitor gene complex in oviduct nuclei and relative location of CR1 repetitive sequences.
Biochemistry 1987;26(21):6831-40.
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1987: Conneely O M; Dobson A D; Tsai M J; Beattie W G; Toft D O; Huckaby C S; Zarucki T; Schrader W T; O'Malley B W
Sequence and expression of a functional chicken progesterone receptor.
Molecular endocrinology (Baltimore, Md.) 1987;1(8):517-25.
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1986: Kleinsek D A; Beattie W G; Tsai M J; O'Malley B W
Molecular cloning of a steroid-regulated 108K heat shock protein gene from hen oviduct.
Nucleic acids research 1986;14(24):10053-69.
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