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Wen-Po Tsai

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Adriano Boasso; Monica Vaccari; Dietmar Fuchs; Andrew W Hardy; Wen-Po Tsai; Elzbieta Tryniszewska; Gene M Shearer; Genoveffa Franchini
Combined effect of antiretroviral therapy and blockade of IDO in SIV-infected rhesus macaques.
Monica Vaccari; Joseph Mattapallil; Kaimei Song; Wen-Po Tsai; Anna Hryniewicz; David Venzon; Maurizio Zanetti; Keith A Reimann; Mario Roederer; Genoveffa Franchini
Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency.
Valentina Cecchinato; Elzbieta Tryniszewska; Zhong Min Ma; Monica Vaccari; Adriano Boasso; Wen-Po Tsai; Constantinos Petrovas; Dietmar Fuchs; Jean-Michel Heraud; David Venzon; Gene M Shearer; Richard A Koup; Israel Lowy; Christopher J Miller; Genoveffa Franchini
Immune activation driven by CTLA-4 blockade augments viral replication at mucosal sites in simian immunodeficiency virus infection.

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All Publications

2009: Adriano Boasso; Monica Vaccari; Dietmar Fuchs; Andrew W Hardy; Wen-Po Tsai; Elzbieta Tryniszewska; Gene M Shearer; Genoveffa Franchini
Combined effect of antiretroviral therapy and blockade of IDO in SIV-infected rhesus macaques.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4313-20.
2008: Monica Vaccari; Joseph Mattapallil; Kaimei Song; Wen-Po Tsai; Anna Hryniewicz; David Venzon; Maurizio Zanetti; Keith A Reimann; Mario Roederer; Genoveffa Franchini
Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency.
Journal of virology 2008;82(19):9629-38.
2008: Valentina Cecchinato; Elzbieta Tryniszewska; Zhong Min Ma; Monica Vaccari; Adriano Boasso; Wen-Po Tsai; Constantinos Petrovas; Dietmar Fuchs; Jean-Michel Heraud; David Venzon; Gene M Shearer; Richard A Koup; Israel Lowy; Christopher J Miller; Genoveffa Franchini
Immune activation driven by CTLA-4 blockade augments viral replication at mucosal sites in simian immunodeficiency virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5439-47.
2007: Anna Hryniewicz; David A Price; Marcin Moniuszko; Adriano Boasso; Yvette Edghill-Spano; Sadie M West; David Venzon; Monica Vaccari; Wen-Po Tsai; Elzbieta Tryniszewska; Janos Nacsa; Francios VILLINGER; Aftab A Ansari; Christopher J Trindade; Michel MORRE; David Brooks; Philip M Arlen; Helen J Brown; Christina Kitchen; Jerome A Zack; Daniel C Douek; Gene M Shearer; Mark G Lewis; Richard A Koup; Genoveffa Franchini
Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3492-504.
2006: Marcin Moniuszko; Yvette Edghill Spano; David Venzon; Liljana Stevceva; Janos Nacsa; Elzbieta Tryniszewska; Wen-Po Tsai; Genoveffa Franchini
Decreased number of CD4+ and CD8+ T cells that express the interleukin-7 receptor in blood and tissues of SIV-infected macaques.
Virology 2006;356(1-2):188-97.
2006: Anna Hryniewicz; Adriano Boasso; Yvette Edghill Spano; Monica Vaccari; Dietmar Fuchs; David Venzon; Janos Nacsa; Michael R Betts; Wen-Po Tsai; Jean-Michel Heraud; Brigitte Beer; Diann Blanset; Claire Chougnet; Israel Lowy; Gene M Shearer; Genoveffa Franchini
CTLA-4 blockade decreases TGF-beta, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques.
Blood 2006;108(12):3834-42.
2006: Jean-Michel Heraud; Yvette Edghill Spano; Victor Ayala; Irene Kalisz; Janie Parrino; Vaniambadi S Kalyanaraman; Jody Manischewitz; Lisa R King; Anna Hryniewicz; Christopher J Trindade; Meredith Hassett; Wen-Po Tsai; David Venzon; Aysegul Nalca; Monica Vaccari; Peter Silvera; Mike Bray; Barney S Graham; Hana Golding; Jay W Hooper; Genoveffa Franchini
Subunit recombinant vaccine protects against monkeypox.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2552-64.
2006: Zdenek Hel; Wen-Po Tsai; Elzbieta Tryniszewska; Janos Nacsa; Phillip D Markham; Mark G Lewis; George Pavlakis; Barbara K Felber; Jim Tartaglia; Genoveffa Franchini
Improved vaccine protection from simian AIDS by the addition of nonstructural simian immunodeficiency virus genes.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):85-96.
2005: Janos Nacsa; Yvette Edghill Spano; Wen-Po Tsai; David Venzon; Elzbieta Tryniszewska; Anna Hryniewicz; Marcin Moniuszko; Audrey Kinter; Kendall A Smith; Genoveffa Franchini
Contrasting effects of low-dose IL-2 on vaccine-boosted simian immunodeficiency virus (SIV)-specific CD4+ and CD8+ T cells in macaques chronically infected with SIVmac251.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):1913-21.
2004: Marcin Moniuszko; Terry J Fry; Wen-Po Tsai; Michel MORRE; Brigitte Assouline; Pierre Cortez; Mark G Lewis; J S Cairns; CRYSTAL MACKALL; Genoveffa Franchini
Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo.
Journal of virology 2004;78(18):9740-9.
2004: Janos Nacsa; Antonia Radaelli; Yvette Edghill Spano; David Venzon; Wen-Po Tsai; Carlo De Giuli Morghen; Dennis Panicali; Jim Tartaglia; Genoveffa Franchini
Avipox-based simian immunodeficiency virus (SIV) vaccines elicit a high frequency of SIV-specific CD4+ and CD8+ T-cell responses in vaccinia-experienced SIVmac251-infected macaques.
Vaccine 2004;22(5-6):597-606.
2003: Marcin Moniuszko; Charlie Brown; Ranajit Pal; Elzbieta Tryniszewska; Wen-Po Tsai; Vanessa M Hirsch; Genoveffa Franchini
High frequency of virus-specific CD8+ T cells in the central nervous system of macaques chronically infected with simian immunodeficiency virus SIVmac251.
Journal of virology 2003;77(22):12346-51.
2003: Yvette Edghill Spano; David Venzon; Tatiana S Karpova; James McNally; Janos Nacsa; Wen-Po Tsai; Elzbieta Tryniszewska; Marcin Moniuszko; Jody Manischewitz; Lisa R King; Steven J Snodgrass; John Parrish; Phillip Markham; Marsha Sowers; Derrick Martin; Mark G Lewis; Jay A Berzofsky; Igor M Belyakov; Bernard Moss; Jim Tartaglia; Mike Bray; Vanessa M Hirsch; Hana Golding; Genoveffa Franchini
Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques.
The Journal of infectious diseases 2003;188(8):1181-91.
2003: Antonia Radaelli; Janos Nacsa; Wen-Po Tsai; Yvette Edghill Spano; Carlo Zanotto; Veronica Elli; David Venzon; Elzbieta Tryniszewska; Phillip Markham; Gail P Mazzara; Dennis Panicali; Carlo De Giuli Morghen; Genoveffa Franchini
Prior DNA immunization enhances immune response to dominant and subdominant viral epitopes induced by a fowlpox-based SIVmac vaccine in long-term slow-progressor macaques infected with SIVmac251.
Virology 2003;312(1):181-95.
2003: Janos Nacsa; Jennifer Stanton; Kevin Kunstman; Wen-Po Tsai; David Ian Watkins; Steven Wolinsky; Genoveffa Franchini
Emergence of cytotoxic T lymphocyte escape mutants following antiretroviral treatment suspension in rhesus macaques infected with SIVmac251.
Virology 2003;305(1):210-8.
2002: Zdenek Hel; Janos Nacsa; Wen-Po Tsai; Arthur Thornton; Laura Giuliani; Jim Tartaglia; Genoveffa Franchini
Equivalent immunogenicity of the highly attenuated poxvirus-based ALVAC-SIV and NYVAC-SIV vaccine candidates in SIVmac251-infected macaques.
Virology 2002;304(1):125-34.
2002: Zdenek Hel; Janos Nacsa; Elzbieta Tryniszewska; Wen-Po Tsai; Robyn Washington Parks; David C Montefiori; Barbara K Felber; Jim Tartaglia; George Pavlakis; Genoveffa Franchini
Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):4778-87.
2002: Zdenek Hel; Elzbieta Tryniszewska; Wen-Po Tsai; Julie M Johnson; Robert Harrod; Jake R Fullen; Vaniambadi S Kalyanaraman; John D Altman; James McNally; Tatiana S Karpova; Barbara K Felber; Jim Tartaglia; Genoveffa Franchini
Design and in vivo immunogenicity of a polyvalent vaccine based on SIVmac regulatory genes.
DNA and cell biology 2002;21(9):619-26.
2002: Zdenek Hel; Julie M Johnson; Elzbieta Tryniszewska; Wen-Po Tsai; Robert Harrod; Jake R Fullen; Jim Tartaglia; Genoveffa Franchini
A novel chimeric Rev, Tat, and Nef (Retanef) antigen as a component of an SIV/HIV vaccine.
Vaccine 2002;20(25-26):3171-86.
2001: Zdenek Hel; Wen-Po Tsai; A Thornton; Janos Nacsa; Laura Giuliani; Elzbieta Tryniszewska; M Poudyal; David Venzon; X Wang; John D Altman; David Ian Watkins; Wuyuan Lu; Agneta S von Gegerfelt; Barbara K Felber; Jim Tartaglia; George Pavlakis; Genoveffa Franchini
Potentiation of simian immunodeficiency virus (SIV)-specific CD4(+) and CD8(+) T cell responses by a DNA-SIV and NYVAC-SIV prime/boost regimen.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):7180-91.
2001: Zdenek Hel; Janos Nacsa; Brian Kelsall; Wen-Po Tsai; Norman L Letvin; Robyn Washington Parks; Elzbieta Tryniszewska; Louis J Picker; Mark G Lewis; Yvette Edghill Spano; Marcin Moniuszko; Ranajit Pal; Liljana Stevceva; John D Altman; Todd M Allen; D Watkins; José V Torres; Jay A Berzofsky; Igor M Belyakov; Warren Strober; Genoveffa Franchini
Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques.
Journal of virology 2001;75(23):11483-95.
2000: Zdenek Hel; David Venzon; M Poudyal; Wen-Po Tsai; Laura Giuliani; ruth woodward; Claire Chougnet; G Shearer; John D Altman; D Watkins; Norbert Bischofberger; Alash'Le Abimiku; Phillip Markham; Jim Tartaglia; Genoveffa Franchini
Viremia control following antiretroviral treatment and therapeutic immunization during primary SIV251 infection of macaques.
Nature medicine 2000;6(10):1140-6.