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Desirée Tsao

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TOP 3
Derek C Cole; Magda Asselin; Agnes Brennan; Robert Czerwinski; John W Ellingboe; Lori Fitz; Rita Greco; Xinyi Huang; Diane Joseph-McCarthy; Michael F Kelly; Matthew Kirisits; Julie Lee; Yuanhong Li; Paul Morgan; Joseph R Stock; Desirée H H Tsao; Allan Wissner; Xiaoke Yang; Divya Chaudhary
Identification, characterization and initial hit-to-lead optimization of a series of 4-arylamino-3-pyridinecarbonitrile as protein kinase C theta (PKCtheta) inhibitors.
Michelle A Markus; Brian Dwyer; Scott Wolfrom; Jianchang Li; Wei Li; Karl Malakian; James Wilhelm; Desirée H H Tsao
Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor.
Desirée H H Tsao; Wah-Tung Hum; Sang Hsu; Karl Malakian; Lih-Ling Lin
The NMR structure of the TRADD death domain, a key protein in the TNF signaling pathway.

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All Publications

2008: Derek C Cole; Magda Asselin; Agnes Brennan; Robert Czerwinski; John W Ellingboe; Lori Fitz; Rita Greco; Xinyi Huang; Diane Joseph-McCarthy; Michael F Kelly; Matthew Kirisits; Julie Lee; Yuanhong Li; Paul Morgan; Joseph R Stock; Desirée H H Tsao; Allan Wissner; Xiaoke Yang; Divya Chaudhary
Identification, characterization and initial hit-to-lead optimization of a series of 4-arylamino-3-pyridinecarbonitrile as protein kinase C theta (PKCtheta) inhibitors.
Journal of medicinal chemistry 2008;51(19):5958-63.
2008: Michelle A Markus; Brian Dwyer; Scott Wolfrom; Jianchang Li; Wei Li; Karl Malakian; James Wilhelm; Desirée H H Tsao
Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor.
Journal of biomolecular NMR 2008;41(1):55-60.
2007: Desirée H H Tsao; Wah-Tung Hum; Sang Hsu; Karl Malakian; Lih-Ling Lin
The NMR structure of the TRADD death domain, a key protein in the TNF signaling pathway.
Journal of biomolecular NMR 2007;39(4):337-42.
2007: Neelu Kaila; Kristin Janz; Adrian Huang; Alessandro Moretto; Silvano DeBernardo; Patricia W Bedard; Steve Tam; Valerie Clerin; James Carl Keith; Desirée H H Tsao; Natalia Sushkova; Gray D Shaw; Raymond T Camphausen; Robert G Schaub; Qin Wang
2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[H]quinoline-4-carboxylic acid (PSI-697): identification of a clinical candidate from the quinoline salicylic acid series of P-selectin antagonists.
Journal of medicinal chemistry 2007;50(1):40-64.
2007: Neelu Kaila; Kristin Janz; Silvano DeBernardo; Patricia W Bedard; Raymond T Camphausen; Steve Tam; Desirée H H Tsao; James Carl Keith; Cheryl Nickerson-Nutter; Adam Shilling; Ruth Young-Sciame; Qin Wang
Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists.
Journal of medicinal chemistry 2007;50(1):21-39.
2006: Desirée H H Tsao; Alan G Sutherland; Lee D Jennings; Yuanhong Li; Thomas S Rush; Juan Alvarez; Weidong Ding; Elizabeth G Dushin; Russell G Dushin; Steven A Haney; Cynthia H Kenny; A Karl Malakian; Ramaswamy Nilakantan; Lidia Mosyak
Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design.
Bioorganic & medicinal chemistry 2006;14(23):7953-61.
2005: Neelu Kaila; William S Somers; Bert Thomas; Paresh Thakker; Kristin Janz; Silvano DeBernardo; Steve Tam; William J Moore; Ruiyang Yang; Wojciech Wrona; Patricia W Bedard; Deidre Crommie; James Carl Keith; Desirée H H Tsao; Juan Alvarez; Heyu Ni; Erik Marchese; John T Patton; John L Magnani; Raymond T Camphausen
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.
Journal of medicinal chemistry 2005;48(13):4346-57.
2005: Michelle A Markus; Brian Dwyer; Scott Wolfrom; Jianchang Li; Wei Li; Karl Malakian; James Wilhelm; Desirée H H Tsao
1H, 13C, and 15N assignments of MMP-12, a key protease implicated in lung tissue remodeling.
Journal of biomolecular NMR 2005;31(3):260.
2004: Lee D Jennings; Kenneth W Foreman; Thomas S Rush; Desirée H H Tsao; Lidia Mosyak; Scott L Kincaid; Mohani N Sukhdeo; Alan G Sutherland; Weidong Ding; Cynthia Hess Kenny; Chantel L Sabus; Hanlan Liu; Elizabeth G Dushin; Soraya L Moghazeh; Pornpen Labthavikul; Peter J Petersen; Margareta Tuckman; Steven A Haney; Alexey Ruzin
Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction.
Bioorganic & medicinal chemistry 2004;12(19):5115-31.
2004: Desirée H H Tsao; Wah-Tung Hum; Sang Hsu; Michelle McGuire; Karl Malakian; Lih-Ling Lin
Assignment of 1H, 13C and 15N resonances of the death domain of TRADD.
Journal of biomolecular NMR 2004;28(4):407-8.
2004: Lee D Jennings; Kenneth W Foreman; Thomas S Rush; Desirée H H Tsao; Lidia Mosyak; Yuanhong Li; Mohani N Sukhdeo; Weidong Ding; Elizabeth G Dushin; Cynthia Hess Kenny; Soraya L Moghazeh; Peter J Petersen; Alexey Ruzin; Margareta Tuckman; Alan G Sutherland
Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction.
Bioorganic & medicinal chemistry letters 2004;14(6):1427-31.
2004: Michelle A Markus; Lisa Doliveira; Karl Malakian; David Keeney; Anatoly Severin; Kathryn W Underwood; Desirée H H Tsao
1H, 13C, and 15N backbone assignments and secondary structure for the 60.8 kD dimer of the NAD+ synthetase from Bacillus subtilis.
Journal of biomolecular NMR 2004;28(3):301-2.
2003: Alan G Sutherland; Juan Alvarez; Weidong Ding; Kenneth W Foreman; Cynthia Hess Kenny; Pornpen Labthavikul; Lidia Mosyak; Peter J Petersen; Thomas S Rush; Alexey Ruzin; Desirée H H Tsao; Karen L Wheless
Structure-based design of carboxybiphenylindole inhibitors of the ZipA-FtsZ interaction.
Organic & biomolecular chemistry 2003;1(23):4138-40.
2002: Neelu Kaila; Lihren Chen; Bert Thomas; Desirée H H Tsao; Steve Tam; Patricia W Bedard; Raymond T Camphausen; Juan Alvarez; Giliyar Ullas
Beta-C-mannosides as selectin inhibitors.
Journal of medicinal chemistry 2002;45(8):1563-6.
2000: Desirée H H Tsao; T McDonagh; Jean-Baptiste Telliez; Sang Hsu; Karl Malakian; GY Xu; Lih-Ling Lin
Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway.
Molecular cell 2000;5(6):1051-7.