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Eishun Tsuchida

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
58
Takeoka, Shinji
47
Sakai, Hiromi
40
Komatsu, Teruyuki
33
Nishide, Hiroyuki
27
Kobayashi, Koichi
17
Horinouchi, Hirohisa
15
Nakagawa, Akito
12
Sou, Keitaro
10
Teramura, Yuji
9
Ikeda, Hisami
8
Huang, Yubin
8
Fujihara, Mitsuhiro
7
Abe, Hideki
7
Takeoka, Shinji
6
Wakamoto, Shinobu

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Publications

TOP 3
Taguchi Kazuaki; Urata Yukino; Anraku Makoto; Watanabe Hiroshi; Kadowaki Daisuke; Sakai Hiromi; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun; Maruyama Toru; Otagiri Masaki
Hemoglobin vesicles, polyethylene glycol (PEG)ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice.
Komatsu Teruyuki; Nakagawa Akito; Curry Stephen; Tsuchida Eishun; Murata Kenichi; Nakamura Nobuhumi; Ohno Hiroyuki
The role of an amino acid triad at the entrance of the heme pocket in human serum albumin for O(2) and CO binding to iron protoporphyrin IX.
Plock Jan A; Rafatmehr Nassim; Sinovcic Dubravko; Schnider Jonas; Sakai Hiromi; Tsuchida Eishun; Banic Andrej; Erni Dominique
Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice.

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All Publications

2009: Taguchi Kazuaki; Urata Yukino; Anraku Makoto; Watanabe Hiroshi; Kadowaki Daisuke; Sakai Hiromi; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun; Maruyama Toru; Otagiri Masaki
Hemoglobin vesicles, polyethylene glycol (PEG)ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(11):2197-203.
2009: Komatsu Teruyuki; Nakagawa Akito; Curry Stephen; Tsuchida Eishun; Murata Kenichi; Nakamura Nobuhumi; Ohno Hiroyuki
The role of an amino acid triad at the entrance of the heme pocket in human serum albumin for O(2) and CO binding to iron protoporphyrin IX.
Organic & biomolecular chemistry 2009;7(18):3836-41.
2009: Plock Jan A; Rafatmehr Nassim; Sinovcic Dubravko; Schnider Jonas; Sakai Hiromi; Tsuchida Eishun; Banic Andrej; Erni Dominique
Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice.
American journal of physiology. Heart and circulatory physiology 2009;297(3):H905-10.
2009: Sakai Hiromi; Okamoto Michiko; Ikeda Eiji; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Histopathological changes of rat brain after direct injection of Hb-vesicles (artificial oxygen carriers) and neurological impact in an intracerebral hemorrhage model.
Journal of biomedical materials research. Part A 2009;90(4):1107-19.
2009: Sakai Hiromi; Sato Atsushi; Takeoka Shinji; Tsuchida Eishun
Mechanism of flocculate formation of highly concentrated phospholipid vesicles suspended in a series of water-soluble biopolymers.
Biomacromolecules 2009;10(8):2344-50.
2009: Sakai Hiromi; Sato Atsushi; Okuda Naoto; Takeoka Shinji; Maeda Nobuji; Tsuchida Eishun
Peculiar flow patterns of RBCs suspended in viscous fluids and perfused through a narrow tube (25 microm).
American journal of physiology. Heart and circulatory physiology 2009;297(2):H583-9.
2009: Taguchi Kazuaki; Urata Yukino; Anraku Makoto; Maruyama Toru; Watanabe Hiroshi; Sakai Hiromi; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun; Kai Toshiya; Otagiri Masaki
Pharmacokinetic study of enclosed hemoglobin and outer lipid component after the administration of hemoglobin vesicles as an artificial oxygen carrier.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(7):1456-63.
2009: Sato Takaaki; Sakai Hiromi; Sou Keitaro; Medebach Martin; Glatter Otto; Tsuchida Eishun
Static structures and dynamics of hemoglobin vesicle (HBV) developed as a transfusion alternative.
The journal of physical chemistry. B 2009;113(24):8418-28.
2009: Taguchi Kazuaki; Maruyama Toru; Iwao Yasunori; Sakai Hiromi; Kobayashi Koichi; Horinouchi Hirohisa; Tsuchida Eishun; Kai Toshiya; Otagiri Masaki
Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model.
Journal of controlled release : official journal of the Controlled Release Society 2009;136(3):232-9.
2009: Yamaguchi Miki; Fujihara Mitsuhiro; Wakamoto Shinobu; Sakai Hiromi; Takeoka Shinji; Tsuchida Eishun; Hamada Hirofumi; Azuma Hiroshi; Ikeda Hisami
Biocompatibility study of hemoglobin vesicles, cellular-type artificial oxygen carriers, with human umbilical cord hematopoietic stem/progenitor cells using an in vitro expansion system.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2009;55(3):200-5.
2009: Sakai Hiromi; Horinouchi Hirohisa; Tsuchida Eishun; Kobayashi Koichi
Hemoglobin vesicles and red blood cells as carriers of carbon monoxide prior to oxygen for resuscitation after hemorrhagic shock in a rat model.
Shock (Augusta, Ga.) 2009;31(5):507-14.
2009: Sakai Hiromi; Sou Keitaro; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Review of hemoglobin-vesicles as artificial oxygen carriers.
Artificial organs 2009;33(2):139-45.
2009: Sakai Hiromi; Seishi Yasushi; Obata Yosuke; Takeoka Shinji; Horinouichi Hirohisa; Tsuchida Eishun; Kobayashi Koichi
Fluid resuscitation with artificial oxygen carriers in hemorrhaged rats: profiles of hemoglobin-vesicle degradation and hematopoiesis for 14 days.
Shock (Augusta, Ga.) 2009;31(2):192-200.
2009: Yamaguchi Miki; Fujihara Mitsuhiro; Wakamoto Shinobu; Sakai Hiromi; Takeoka Shinji; Tsuchida Eishun; Azuma Hiroshi; Ikeda Hisami
Influence of hemoglobin vesicles, cellular-type artificial oxygen carriers, on human umbilical cord blood hematopoietic progenitor cells in vitro.
Journal of biomedical materials research. Part A 2009;88(1):34-42.
2009: Sakai Hiromi; Sou Keitaro; Tsuchida Eishun
Hemoglobin-vesicles as an artificial oxygen carrier.
Methods in enzymology 2009;465():363-84.
2008: Sakai Hiromi; Sato Atsushi; Sobolewski Peter; Takeoka Shinji; Frangos John A; Kobayashi Koichi; Intaglietta Marcos; Tsuchida Eishun
NO and CO binding profiles of hemoglobin vesicles as artificial oxygen carriers.
Biochimica et biophysica acta 2008;1784(10):1441-7.
2008: Ma Feng; Ebihara Yasuhiro; Umeda Katsutsugu; Sakai Hiromi; Hanada Sachiyo; Zhang Hong; Zaike Yuji; Tsuchida Eishun; Nakahata Tatsutoshi; Nakauchi Hiromitsu; Tsuji Kohichiro
Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13087-92.
2008: Qu Xue; Komatsu Teruyuki; Sato Takaaki; Glatter Otto; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Structure, photophysical property, and cytotoxicity of human serum albumin complexed with tris(dicarboxymethylene)[60]fullerene.
Bioconjugate chemistry 2008;19(8):1556-60.
2008: Horinouchi Hirohisa; Yamamoto Hisashi; Komatsu Teruyuki; Huang Yubin; Tsuchida Eishun; Kobayashi Koichi
Enhanced radiation response of a solid tumor with the artificial oxygen carrier 'albumin-heme'.
Cancer science 2008;99(6):1274-8.
2008: Fujimi Akihito; Matsunaga Takuya; Kobune Masayoshi; Kawano Yutaka; Nagaya Taiko; Tanaka Ikuta; Iyama Satoshi; Hayashi Tsuyoshi; Sato Tsutomu; Miyanishi Koji; Sagawa Tamotsu; Sato Yasushi; Takimoto Rishu; Takayama Tetsuji; Kato Junji; Gasa Shinsei; Sakai Hiromi; Tsuchida Eishun; Ikebuchi Kenji; Hamada Hirofumi; Niitsu Yoshiro
Ex vivo large-scale generation of human red blood cells from cord blood CD34+ cells by co-culturing with macrophages.
International journal of hematology 2008;87(4):339-50.
2008: Sou Keitaro; Tsuchida Eishun
Electrostatic interactions and complement activation on the surface of phospholipid vesicle containing acidic lipids: effect of the structure of acidic groups.
Biochimica et biophysica acta 2008;1778(4):1035-41.
2008: Nakagawa Akito; Komatsu Teruyuki; Iizuka Makoto; Tsuchida Eishun
O2 binding to human serum albumin incorporating iron porphyrin with a covalently linked methyl-L-histidine isomer.
Bioconjugate chemistry 2008;19(3):581-4.
2008: Sou Keitaro; Inenaga Shunsuke; Takeoka Shinji; Tsuchida Eishun
Loading of curcumin into macrophages using lipid-based nanoparticles.
International journal of pharmaceutics 2008;352(1-2):287-93.
2008: Sakai H; Sou K; Horinouchi H; Kobayashi K; Tsuchida E
Haemoglobin-vesicles as artificial oxygen carriers: present situation and future visions.
Journal of internal medicine 2008;263(1):4-15.
2008: Sakai Hiromi; Sato Atsushi; Masuda Kaoru; Takeoka Shinji; Tsuchida Eishun
Encapsulation of concentrated hemoglobin solution in phospholipid vesicles retards the reaction with NO, but not CO, by intracellular diffusion barrier.
The Journal of biological chemistry 2008;283(3):1508-17.
2008: Qu Xue; Lu Gang; Tsuchida Eishun; Komatsu Teruyuki
Protein nanotubes comprised of an alternate layer-by-layer assembly using a polycation as an electrostatic glue.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(33):10303-8.
2007: Komatsu Teruyuki; Nakagawa Akito; Zunszain Patricia A; Curry Stephen; Tsuchida Eishun
Genetic engineering of the heme pocket in human serum albumin: modulation of O2 binding of iron protoporphyrin IX by variation of distal amino acids.
Journal of the American Chemical Society 2007;129(36):11286-95.
2007: Nakagawa Akito; Komatsu Teruyuki; Huang Yubin; Lu Gang; Tsuchida Eishun
O2-binding albumin thin films: solid membranes of poly(ethylene glycol)-conjugated human serum albumin incorporating iron porphyrin.
Bioconjugate chemistry 2007;18(5):1673-7.
2007: Lu Gang; Komatsu Teruyuki; Tsuchida Eishun
Artificial hemoprotein nanotubes.
Chemical communications (Cambridge, England) 2007;(28):2980-2.
2007: Sakai Hiromi; Sato Atsushi; Takeoka Shinji; Tsuchida Eishun
Rheological properties of hemoglobin vesicles (artificial oxygen carriers) suspended in a series of plasma-substitute solutions.
Langmuir : the ACS journal of surfaces and colloids 2007;23(15):8121-8.
2007: Sou Keitaro; Goins Beth; Takeoka Shinji; Tsuchida Eishun; Phillips William T
Selective uptake of surface-modified phospholipid vesicles by bone marrow macrophages in vivo.
Biomaterials 2007;28(16):2655-66.
2007: Komatsu Teruyuki; Huang Yubin; Wakamoto Shinobu; Abe Hideki; Fujihara Mitsuhiro; Azuma Hiroshi; Ikeda Hisami; Yamamoto Hisashi; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Influence of O(2)-carrying plasma hemoprotein "albumin-heme" on complement system and platelet activation in vitro and physiological responses to exchange transfusion.
Journal of biomedical materials research. Part A 2007;81(4):821-6.
2007: Sato Takaaki; Komatsu Teruyuki; Nakagawa Akito; Tsuchida Eishun
Induced long-range attractive potentials of human serum albumin by ligand binding.
Physical review letters 2007;98(20):208101.
2007: Plock Jan A; Tromp Annemarie E; Contaldo Claudio; Spanholtz Timo; Sinovcic Dubravko; Sakai Hiromi; Tsuchida Eishun; Leunig Michael; Banic Andrej; Erni Dominique
Hemoglobin vesicles reduce hypoxia-related inflammation in critically ischemic hamster flap tissue.
Critical care medicine 2007;35(3):899-905.
2007: Sato Takaaki; Sakai Hiromi; Sou Keitaro; Buchner Richard; Tsuchida Eishun
Poly(ethylene glycol)-conjugated phospholipids in aqueous micellar solutions: hydration, static structure, and interparticle interactions.
The journal of physical chemistry. B 2007;111(6):1393-401.
2007: Sakai Hiromi; Tsuchida Eishun
Hemoglobin-vesicles for a transfusion alternative and targeted oxygen delivery.
Journal of liposome research 2007;17(3-4):227-35.
2007: Abe Hideki; Azuma Hiroshi; Yamaguchi Miki; Fujihara Mitsuhiro; Ikeda Hisami; Sakai Hiromi; Takeoka Shinji; Tsuchida Eishun
Effects of hemoglobin vesicles, a liposomal artificial oxygen carrier, on hematological responses, complement and anaphylactic reactions in rats.
Artificial cells, blood substitutes, and immobilization biotechnology 2007;35(2):157-72.
2007: Sakai Hiromi; Tsuchida Eishun; Horinouchi Hirohisa; Kobayashi Koichi
One-year observation of Wistar rats after intravenous infusion of hemoglobin-vesicles (artificial oxygen carriers).
Artificial cells, blood substitutes, and immobilization biotechnology 2007;35(1):81-91.
2006: Goto Yoshitugu; Terajima Katsuyuki; Tsueshita Takaya; Miyashita Masao; Horinouchi Hirohisa; Sakai Hiromi; Tsuchida Eishun; Sakamoto Atsuhiro
Fluid resuscitation with hemoglobin-vesicle solution does not increase hypoxia or inflammatory responses in moderate hemorrhagic shock.
Biomedical research (Tokyo, Japan) 2006;27(6):283-8.
2006: Komatsu Teruyuki; Wang Rong-Min; Zunszain Patricia A; Curry Stephen; Tsuchida Eishun
Photosensitized reduction of water to hydrogen using human serum albumin complexed with zinc-protoporphyrin IX.
Journal of the American Chemical Society 2006;128(50):16297-301.
2006: Atoji Tomoyasu; Aihara Motonari; Sakai Hiromi; Tsuchida Eishun; Takeoka Shinji
Hemoglobin vesicles containing methemoglobin and L-tyrosine to suppress methemoglobin formation in vitro and in vivo.
Bioconjugate chemistry 2006;17(5):1241-5.
2006: Huang Yubin; Komatsu Teruyuki; Yamamoto Hisashi; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
PEGylated albumin-heme as an oxygen-carrying plasma expander: Exchange transfusion into acute anemia rat model.
Biomaterials 2006;27(25):4477-83.
2006: Huang Yubin; Komatsu Teruyuki; Wang Rong-Min; Nakagawa Akito; Tsuchida Eishun
Poly(ethylene glycol)-conjugated human serum albumin including iron porphyrins: surface modification improves the O2-transporting ability.
Bioconjugate chemistry 2006;17(2):393-8.
2006: Sakai Hiromi; Horinouchi Hirohisa; Yamamoto Manabu; Ikeda Eiji; Takeoka Shinji; Takaori Masuhiko; Tsuchida Eishun; Kobayashi Koichi
Acute 40 percent exchange-transfusion with hemoglobin-vesicles (HbV) suspended in recombinant human serum albumin solution: degradation of HbV and erythropoiesis in a rat spleen for 2 weeks.
Transfusion 2006;46(3):339-47.
2006: Nakagawa Akito; Komatsu Teruyuki; Iizuka Makoto; Tsuchida Eishun
Human serum albumin hybrid incorporating tailed porphyrinatoiron(II) in the alpha,alpha,alpha,beta-conformer as an O2-binding site.
Bioconjugate chemistry 2006;17(1):146-51.
2006: Tsuchida Eishun; Sakai Hiromi; Horinouchi Hirohisa; Kobayashi Koichi
Hemoglobin-vesicles as a transfusion alternative.
Artificial cells, blood substitutes, and immobilization biotechnology 2006;34(6):581-8.
2006: Sakai Hiromi; Tsuchida Eishun
Performances of PEG-modified hemoglobin-vesicles as artificial oxygen carriers in microcirculation.
Clinical hemorheology and microcirculation 2006;34(1-2):335-40.
2006: Abe Hideki; Fujihara Mitsuhiro; Azuma Hiroshi; Ikeda Hisami; Ikebuchi Kenji; Takeoka Shinji; Tsuchida Eishun; Harashima Hideyoshi
Interaction of hemoglobin vesicles, a cellular-type artificial oxygen carrier, with human plasma: effects on coagulation, kallikrein-kinin, and complement systems.
Artificial cells, blood substitutes, and immobilization biotechnology 2006;34(1):1-10.
2005: Plock Jan A; Contaldo Claudio; Sakai Hiromi; Tsuchida Eishun; Leunig Michael; Banic Andrej; Menger Michael D; Erni Dominique
Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?
American journal of physiology. Heart and circulatory physiology 2005;289(6):H2624-31.
2005: Komatsu Teruyuki; Oguro Yukiko; Nakagawa Akito; Tsuchida Eishun
Albumin clusters: structurally defined protein tetramer and oxygen carrier including thirty-two iron(II) porphyrins.
Biomacromolecules 2005;6(6):3397-403.
2005: Komatsu Teruyuki; Ohmichi Naomi; Nakagawa Akito; Zunszain Patricia A; Curry Stephen; Tsuchida Eishun
O2 and CO binding properties of artificial hemoproteins formed by complexing iron protoporphyrin IX with human serum albumin mutants.
Journal of the American Chemical Society 2005;127(45):15933-42.
2005: Okamura Yosuke; Takeoka Shinji; Teramura Yuji; Maruyama Hitomi; Tsuchida Eishun; Handa Makoto; Ikeda Yasuo
Hemostatic effects of fibrinogen gamma-chain dodecapeptide-conjugated polymerized albumin particles in vitro and in vivo.
Transfusion 2005;45(7):1221-8.
2005: Sakai Hiromi; Cabrales Pedro; Tsai Amy G; Tsuchida Eishun; Intaglietta Marcos
Oxygen release from low and normal P50 Hb vesicles in transiently occluded arterioles of the hamster window model.
American journal of physiology. Heart and circulatory physiology 2005;288(6):H2897-903.
2005: Komatsu Teruyuki; Ishihara Seiji; Tsuchida Eishun; Nishide Hiroyuki; Morokuma Chihiro; Nakamura Satoshi
Heat-resistant oxygen-carrying hemoproteins consist of recombinant xylanases and synthetic iron(II) porphyrin.
Biomacromolecules 2005;6(3):1489-94.
2005: Contaldo Claudio; Plock Jan; Sakai Hiromi; Takeoka Shinji; Tsuchida Eishun; Leunig Michael; Banic Andrej; Erni Dominique
New generation of hemoglobin-based oxygen carriers evaluated for oxygenation of critically ischemic hamster flap tissue.
Critical care medicine 2005;33(4):806-12.
2005: Cabrales Pedro; Sakai Hiromi; Tsai Amy G; Takeoka Shinji; Tsuchida Eishun; Intaglietta Marcos
Oxygen transport by low and normal oxygen affinity hemoglobin vesicles in extreme hemodilution.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1885-92.
2005: Sou Keitaro; Klipper Robert; Goins Beth; Tsuchida Eishun; Phillips William T
Circulation kinetics and organ distribution of Hb-vesicles developed as a red blood cell substitute.
The Journal of pharmacology and experimental therapeutics 2005;312(2):702-9.
2005: Wang Rong-Min; Komatsu Teruyuki; Nakagawa Akito; Tsuchida Eishun
Human serum albumin bearing covalently attached iron(II) porphyrins as O2-coordination sites.
Bioconjugate chemistry 2005;16(1):23-6.
2005: Wakamoto Shinobu; Fujihara Mitsuhiro; Abe Hideki; Yamaguchi Miki; Azuma Hiroshi; Ikeda Hisami; Takeoka Shinji; Tsuchida Eishun
Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro.
Artificial cells, blood substitutes, and immobilization biotechnology 2005;33(2):101-11.
2004: Komatsu Teruyuki; Yamamoto Hisashi; Huang Yubin; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Exchange transfusion with synthetic oxygen-carrying plasma protein "albumin-heme" into an acute anemia rat model after seventy-percent hemodilution.
Journal of biomedical materials research. Part A 2004;71(4):644-51.
2004: Sakai Hiromi; Masada Yohei; Horinouchi Hirohisa; Ikeda Eiji; Sou Keitaro; Takeoka Shinji; Suematsu Makoto; Takaori Masuhiko; Kobayashi Koichi; Tsuchida Eishun
Physiological capacity of the reticuloendothelial system for the degradation of hemoglobin vesicles (artificial oxygen carriers) after massive intravenous doses by daily repeated infusions for 14 days.
The Journal of pharmacology and experimental therapeutics 2004;311(3):874-84.
2004: Huang Yubin; Komatsu Teruyuki; Yamamoto Hisashi; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Safety evaluation of an artificial O2 carrier as a red blood cell substitute by blood biochemical tests and histopathology observations.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2004;50(6):525-9.
2004: Komatsu Teruyuki; Oguro Yukiko; Teramura Yuji; Takeoka Shinji; Okai Junpei; Anraku Makoto; Otagiri Masaki; Tsuchida Eishun
Physicochemical characterization of cross-linked human serum albumin dimer and its synthetic heme hybrid as an oxygen carrier.
Biochimica et biophysica acta 2004;1675(1-3):21-31.
2004: Komatsu Teruyuki; Ohmichi Naomi; Zunszain Patricia A; Curry Stephen; Tsuchida Eishun
Dioxygenation of human serum albumin having a prosthetic heme group in a tailor-made heme pocket.
Journal of the American Chemical Society 2004;126(44):14304-5.
2004: Nakagawa Akito; Ohmichi Naomi; Komatsu Teruyuki; Tsuchida Eishun
Synthesis of protoheme IX derivatives with a covalently linked proximal base and their human serum albumin hybrids as artificial hemoprotein.
Organic & biomolecular chemistry 2004;2(21):3108-12.
2004: Huang Yubin; Komatsu Teruyuki; Yamamoto Hisashi; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Exchange transfusion with entirely synthetic red-cell substitute albumin-heme into rats: physiological responses and blood biochemical tests.
Journal of biomedical materials research. Part A 2004;71(1):63-9.
2004: Yoshizu Akira; Izumi Yotaro; Park Sungick; Sakai Hiromi; Takeoka Shinji; Horinouchi Hirohisa; Ikeda Eiji; Tsuchida Eishun; Kobayashi Koichi
Hemorrhagic shock resuscitation with an artificial oxygen carrier, hemoglobin vesicle, maintains intestinal perfusion and suppresses the increase in plasma tumor necrosis factor-alpha.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2004;50(5):458-63.
2004: Sakai Hiromi; Masada Yohei; Onuma Hiroto; Takeoka Shinji; Tsuchida Eishun
Reduction of methemoglobin via electron transfer from photoreduced flavin: restoration of O2-binding of concentrated hemoglobin solution coencapsulated in phospholipid vesicles.
Bioconjugate chemistry 2004;15(5):1037-45.
2004: Sakai Hiromi; Horinouchi Hirohisa; Masada Yohei; Takeoka Shinji; Ikeda Eiji; Takaori Masuhiko; Kobayashi Koichi; Tsuchida Eishun
Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model.
Biomaterials 2004;25(18):4317-25.
2004: Sakai Hiromi; Masada Yohei; Horinouchi Hirohisa; Yamamoto Manabu; Ikeda Eiji; Takeoka Shinji; Kobayashi Koichi; Tsuchida Eishun
Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats.
Critical care medicine 2004;32(2):539-45.
2004: Sakai Hiromi; Hisamoto Shuji; Fukutomi Ippei; Sou Keitaro; Takeoka Shinji; Tsuchida Eishun
Detection of lipopolysaccharide in hemoglobin-vesicles by Limulus amebocyte lysate test with kinetic-turbidimetric gel clotting analysis and pretreatment of surfactant.
Journal of pharmaceutical sciences 2004;93(2):310-21.
2003: Takeoka Shinji; Okamura Yosuke; Teramura Yuji; Watanabe Naohide; Suzuki Hidenori; Tsuchida Eishun; Handa Makoto; Ikeda Yasuo
Function of fibrinogen gamma-chain dodecapeptide-conjugated latex beads under flow.
Biochemical and biophysical research communications 2003;312(3):773-9.
2003: Sakai Hiromi; Suzuki Yoji; Kinoshita Megumi; Takeoka Shinji; Maeda Nobuji; Tsuchida Eishun
O2 release from Hb vesicles evaluated using an artificial, narrow O2-permeable tube: comparison with RBCs and acellular Hbs.
American journal of physiology. Heart and circulatory physiology 2003;285(6):H2543-51.
2003: Teramura Yuji; Kanazawa Hideo; Sakai Hiromi; Takeoka Shinji; Tsuchida Eishun
Prolonged oxygen-carrying ability of hemoglobin vesicles by coencapsulation of catalase in vivo.
Bioconjugate chemistry 2003;14(6):1171-6.
2003: Komatsu Teruyuki; Moritake Miho; Tsuchida Eishun
Molecular energy and electron transfer assemblies made of self-organized lipid-porphyrin bilayer vesicles.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(19):4626-33.
2003: Sou Keitaro; Naito Yoshiyasu; Endo Taro; Takeoka Shinji; Tsuchida Eishun
Effective encapsulation of proteins into size-controlled phospholipid vesicles using freeze-thawing and extrusion.
Biotechnology progress 2003;19(5):1547-52.
2003: Contaldo Claudio; Schramm Sören; Wettstein Reto; Sakai Hiromi; Takeoka Shinji; Tsuchida Eishun; Leunig Michael; Banic Andrej; Erni Dominique
Improved oxygenation in ischemic hamster flap tissue is correlated with increasing hemodilution with Hb vesicles and their O2 affinity.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H1140-7.
2003: Huang Yubin; Komatsu Teruyuki; Nakagawa Akito; Tsuchida Eishun; Kobayashi Shu
Compatibility in vitro of albumin-heme (O(2) carrier) with blood cell components.
Journal of biomedical materials research. Part A 2003;66(2):292-7.
2003: Zunszain Patricia A; Ghuman Jamie; Komatsu Teruyuki; Tsuchida Eishun; Curry Stephen
Crystal structural analysis of human serum albumin complexed with hemin and fatty acid.
BMC structural biology 2003;3():6.
2003: Teramura Yuji; Okamura Yosuke; Takeoka Shinji; Tsuchiyama Hiromi; Narumi Hideki; Kainoh Mie; Handa Makoto; Ikeda Yasuo; Tsuchida Eishun
Hemostatic effects of polymerized albumin particles bearing rGPIa/IIa in thrombocytopenic mice.
Biochemical and biophysical research communications 2003;306(1):256-60.
2003: Oyaizu Kenichi; Tsuchida Eishun
The first oxovanadium ring in [[O[double bond]V(salen)]2(mu-F)][VO(salen)][BF4].(CH2Cl2)x crystals.
Journal of the American Chemical Society 2003;125(19):5630-1.
2003: Erni Dominique; Wettstein Reto; Schramm Sören; Contaldo Claudio; Sakai Hiromi; Takeoka Shinji; Tsuchida Eishun; Leunig Michael; Banic Andrej
Normovolemic hemodilution with Hb vesicle solution attenuates hypoxia in ischemic hamster flap tissue.
American journal of physiology. Heart and circulatory physiology 2003;284(5):H1702-9.
2003: Sakai Hiromi; Tomiyama Kenichi; Masada Yohei; Takeoka Shinji; Horinouchi Hirohisa; Kobayashi Koichi; Tsuchida Eishun
Pretreatment of serum containing hemoglobin vesicles (oxygen carriers) to prevent their interference in laboratory tests.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(2):222-31.
2003: Oyaizu Kenichi; Dewi Eniya Listiani; Tsuchida Eishun
Coordination of BF(4)(-) to oxovanadium(V) complexes, evidenced by the redox potential of oxovanadium(IV/V) couples in CH(2)Cl(2).
Inorganic chemistry 2003;42(4):1070-5.
2003: Tsuchida Eishun; Komatsu Teruyuki; Matsukawa Yasuko; Nakagawa Akito; Sakai Hiromi; Kobayashi Koichi; Suematsu Makoto
Human serum albumin incorporating synthetic heme: red blood cell substitute without hypertension by nitric oxide scavenging.
Journal of biomedical materials research. Part A 2003;64(2):257-61.
2003: Shirasawa Takuji; Izumizaki Masahiko; Suzuki Yo-ichi; Ishihara Akihiko; Shimizu Takahiko; Tamaki Masakatsu; Huang Fei; Koizumi Ken-ichi; Iwase Michiko; Sakai Hiromi; Tsuchida Eishun; Ueshima Kenji; Inoue Hiroshi; Koseki Haruhiko; Senda Toshiya; Kuriyama Takayuki; Homma Ikuo
Oxygen affinity of hemoglobin regulates O2 consumption, metabolism, and physical activity.
The Journal of biological chemistry 2003;278(7):5035-43.
2003: Komatsu Teruyuki; Hayakawa Shoichi; Tsuchida Eishun; Nishide Hiroyuki
Meso-tetrakis[o-(N-methyl)pyridinium]porphyrin ensembles with axially coordinated cyclodextrin-penetrating phenethylimidazole: reversible dioxygen-binding in aqueous DMF solution.
Chemical communications (Cambridge, England) 2003;(1):50-1.
2003: Kobayashi Koichi; Komatsu Teruyuki; Iwamaru Arifumi; Matsukawa Yasuko; Horinouchi Hirohisa; Watanabe Masazumi; Tsuchida Eishun
Oxygenation of hypoxic region in solid tumor by administration of human serum albumin incorporating synthetic hemes.
Journal of biomedical materials research. Part A 2003;64(1):48-51.
2002: Komatsu Teruyuki; Moritake Miho; Nakagawa Akito; Tsuchida Eishun
Self-organized lipid-porphyrin bilayer membranes in vesicular form: nanostructure, photophysical properties, and dioxygen coordination.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(23):5469-80.
2002: Takeoka Shinji; Teramura Yuji; Atoji Tomoyasu; Tsuchida Eishun
Effect of Hb-encapsulation with vesicles on H2O2 reaction and lipid peroxidation.
Bioconjugate chemistry 2002;13(6):1302-8.
2002: Sakai Hiromi; Takeoka Shinji; Wettstein Reto; Tsai Amy G; Intaglietta Marcos; Tsuchida Eishun
Systemic and microvascular responses to hemorrhagic shock and resuscitation with Hb vesicles.
American journal of physiology. Heart and circulatory physiology 2002;283(3):H1191-9.
2002: Takeoka Shinji; Teramura Yuji; Okamura Yosuke; Tsuchida Eishun; Handa Makoto; Ikeda Yasuo
Rolling properties of rGPIbalpha-conjugated phospholipid vesicles with different membrane flexibilities on vWf surface under flow conditions.
Biochemical and biophysical research communications 2002;296(3):765-70.
2002: Suzuki Yo-ichi; Shimizu Takahiko; Sakai Hiromi; Tamaki Masakatsu; Koizumi Ken ichi; Kuriyama Takayuki; Tsuchida Eishun; Koseki Haruhiko; Shirasawa Takuji
Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb.
Biochemical and biophysical research communications 2002;295(4):869-76.
2002: Sakai Hiromi; Sato Toshiyuki; Maekawa Yasunori; Tsuchida Eishun
Capillary blood flow during severe hemodilution observed by a noninvasive transcutaneous technique using flash epi-illumination.
Microvascular research 2002;64(1):120-6.
2002: Komatsu Teruyuki; Matsukawa Yasuko; Tsuchida Eishun
Effect of heme structure on O(2)-binding properties of human serum albumin-heme hybrids: intramolecular histidine coordination provides a stable O(2)-adduct complex.
Bioconjugate chemistry 2002;13(3):397-402.
2002: Sakai Hiromi; Masada Yohei; Takeoka Shinji; Tsuchida Eishun
Characteristics of bovine hemoglobin as a potential source of hemoglobin-vesicles for an artificial oxygen carrier.
Journal of biochemistry 2002;131(4):611-7.
2002: Huang Yubin; Takeoka Shinji; Sakai Hiromi; Abe Hideki; Hirayama Junichi; Ikebuchi Kenji; Ikeda Hisami; Tsuchida Eishun
Complete deoxygenation from a hemoglobin solution by an electrochemical method and heat treatment for virus inactivation.
Biotechnology progress 2002;18(1):101-7.
2001: Ito T; Fujihara M; Abe H; Yamaguchi M; Wakamoto S; Takeoka S; Sakai H; Tsuchida E; Ikeda H; Ikebuchi K
Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on N-formyl-methionyl-leucyl-phenylalanine-induced responses of polymorphonuclear neutrophils in vitro.
Artificial cells, blood substitutes, and immobilization biotechnology 2001;29(6):427-37.
2001: Abe H; Ikebuchi K; Hirayama J; Fujihara M; Takeoka S; Sakai H; Tsuchida E; Ikeda H
Virus inactivation in hemoglobin solution by heat treatment.
Artificial cells, blood substitutes, and immobilization biotechnology 2001;29(5):381-8.
2001: Sakai H; Horinouchi H; Tomiyama K; Ikeda E; Takeoka S; Kobayashi K; Tsuchida E
Hemoglobin-vesicles as oxygen carriers: influence on phagocytic activity and histopathological changes in reticuloendothelial system.
The American journal of pathology 2001;159(3):1079-88.
2001: Nakagawa A; Komatsu T; Tsuchida E
Photoreduction of autooxidized albumin-heme hybrid in saline solution: revival of its O(2)-binding ability.
Bioconjugate chemistry 2001;12(4):648-52.
2001: Nishide H; Ozawa T; Miyasaka M; Tsuchida E
A nanometer-sized high-spin polyradical: poly(4-phenoxyl-1,2-phenylenevinylene) planarily extended in a non-Kekulé fashion and its magnetic force microscopic images.
Journal of the American Chemical Society 2001;123(25):5942-6.
2001: Wakamoto S; Fujihara M; Abe H; Sakai H; Takeoka S; Tsuchida E; Ikeda H; Ikebuchi K
Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on agonist-induced platelet aggregation and RANTES release in vitro.
Artificial cells, blood substitutes, and immobilization biotechnology 2001;29(3):191-201.
2001: Kyokane T; Norimizu S; Taniai H; Yamaguchi T; Takeoka S; Tsuchida E; Naito M; Nimura Y; Ishimura Y; Suematsu M
Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin-treated rat liver.
Gastroenterology 2001;120(5):1227-40.
2001: Nishide H; Doi R; Oyaizu K; Tsuchida E
Electrochemical and ferromagnetic couplings in 4,4',4' '-(1,3,5-benzenetriyl)tris(phenoxyl) radical formation.
The Journal of organic chemistry 2001;66(5):1680-5.
2001: Komatsu T; Matsukawa Y; Tsuchida E
Reaction of nitric oxide with synthetic hemoprotein, human serum albumin incorporating tetraphenylporphinatoiron(II) derivatives.
Bioconjugate chemistry 2001;12(1):71-5.
2001: Takeoka S; Teramura Y; Okamura Y; Handa M; Ikeda Y; Tsuchida E
Fibrinogen-conjugated albumin polymers and their interaction with platelets under flow conditions.
Biomacromolecules 2001;2(4):1192-7.
2000: Sakai H; Onuma H; Umeyama M; Takeoka S; Tsuchida E
Photoreduction of methemoglobin by irradiation in the near-ultraviolet region.
Biochemistry 2000;39(47):14595-602.
2000: Ohkawa H; Teramura Y; Takeoka S; Tsuchida E
Synthesis of multiacyl poly(ethylene glycol) for the conjugation of cytochrome c to phospholipid vesicle.
Bioconjugate chemistry 2000;11(6):815-21.
2000: Komatsu T; Matsukawa Y; Tsuchida E
Kinetics of CO and O(2) binding to human serum albumin-heme hybrid.
Bioconjugate chemistry 2000;11(6):772-6.
2000: Sakai H; Hara H; Yuasa M; Tsai A G; Takeoka S; Tsuchida E; Intaglietta M
Molecular dimensions of Hb-based O(2) carriers determine constriction of resistance arteries and hypertension.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H908-15.
2000: Sakai H; Hara H; Tsai A G; Tsuchida E; Intaglietta M
Constriction of resistance arteries determines l-NAME-induced hypertension in a conscious hamster model.
Microvascular research 2000;60(1):21-7.
2000: Sakai H; Tomiyama K I; Sou K; Takeoka S; Tsuchida E
Poly(ethylene glycol)-conjugation and deoxygenation enable long-term preservation of hemoglobin-vesicles as oxygen carriers in a liquid state.
Bioconjugate chemistry 2000;11(3):425-32.
2000: Sou K; Endo T; Takeoka S; Tsuchida E
Poly(ethylene glycol)-modification of the phospholipid vesicles by using the spontaneous incorporation of poly(ethylene glycol)-lipid into the vesicles.
Bioconjugate chemistry 2000;11(3):372-9.
2000: Sakai H; Yuasa M; Onuma H; Takeoka S; Tsuchida E
Synthesis and physicochemical characterization of a series of hemoglobin-based oxygen carriers: objective comparison between cellular and acellular types.
Bioconjugate chemistry 2000;11(1):56-64.
2000: Tsuchida E; Komatsu T; Hamamatsu K; Matsukawa Y; Tajima A; Yoshizu A; Izumi Y; Kobayashi K
Exchange transfusion with albumin-heme as an artificial O2-infusion into anesthetized rats: physiological responses, O2-delivery, and reduction of the oxidized hemin sites by red blood cells.
Bioconjugate chemistry 2000;11(1):46-50.
2000: Takeoka S; Teramura Y; Ohkawa H; Ikeda Y; Tsuchida E
Conjugation of von Willebrand factor-binding domain of platelet glycoprotein Ib alpha to size-controlled albumin microspheres.
Biomacromolecules 2000;1(2):290-5.
1999: Wakabayashi Y; Takamiya R; Mizuki A; Kyokane T; Goda N; Yamaguchi T; Takeoka S; Tsuchida E; Suematsu M; Ishimura Y
Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of vascular resistance in perfused rat liver.
The American journal of physiology 1999;277(5 Pt 1):G1088-96.
1999: Tsuchida E; Komatsu T; Matsukawa Y; Hamamatsu K; Wu J
Human serum albumin incorporating Tetrakis(o-pivalamido) phenylporphinatoiron(II) derivative as a totally synthetic O2-carrying hemoprotein.
Bioconjugate chemistry 1999;10(5):797-802.
1999: Komatsu T; Hamamatsu K; Wu J; Tsuchida E
Physicochemical properties and O2-coordination structure of human serum albumin incorporating tetrakis(o-pivalamido)phenylporphyrinatoiron(II) derivatives.
Bioconjugate chemistry 1999;10(1):82-6.
1998: Komatsu T; Hamamatsu K; Takeoka S; Nishide H; Tsuchida E
Human serum albumin-bound synthetic hemes as an oxygen carrier: determination of equilibrium constants for heme binding to host albumin.
Artificial cells, blood substitutes, and immobilization biotechnology 1998;26(5-6):519-27.
1998: Kawai N; Ohkawa H; Maejima H; Takeoka S; Nishide H; Tsuchida E
Oxygen releasing from cellular hemoglobin.
Artificial cells, blood substitutes, and immobilization biotechnology 1998;26(5-6):507-17.
1998: Park S; Kose T; Hamasaki M; Takeoka S; Nishide H; Tsuchida E
Effects of the pH-controlled hemoglobin vesicles by CO2 gas.
Artificial cells, blood substitutes, and immobilization biotechnology 1998;26(5-6):497-506.
1998: Goda N; Suzuki K; Naito M; Takeoka S; Tsuchida E; Ishimura Y; Tamatani T; Suematsu M
Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation.
The Journal of clinical investigation 1998;101(3):604-12.
1997: Takeoka S; Sakai H; Kose T; Mano Y; Seino Y; Nishide H; Tsuchida E
Methemoglobin formation in hemoglobin vesicles and reduction by encapsulated thiols.
Bioconjugate chemistry 1997;8(4):539-44.
1997: Tsuchida E; Ando K; Maejima H; Kawai N; Komatsu T; Takeoka S; Nishide H
Properties of and oxygen binding by albumin-tetraphenylporphyrinatoiron(II) derivative complexes.
Bioconjugate chemistry 1997;8(4):534-8.
1997: Izumi Y; Sakai H; Kose T; Hamada K; Takeoka S; Yoshizu A; Horinouchi H; Kato R; Nishide H; Tsuchida E; Kobayashi K
Evaluation of the capabilities of a hemoglobin vesicle as an artificial oxygen carrier in a rat exchange transfusion model.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1997;43(4):289-97.
1997: Kobayashi K; Izumi Y; Yoshizu A; Horinouchi H; Park S I; Sakai H; Takeoka S; Nishide H; Tsuchida E
The oxygen carrying capability of hemoglobin vesicles evaluated in rat exchange transfusion models.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(4):357-66.
1997: Nishide H; Chen X S; Tsuchida E
Facilitated oxygen transport with modified and encapsulated hemoglobins across non-flowing solution membrane.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(4):335-46.
1997: Takeoka S; Ohgushi T; Sakai H; Kose T; Nishide H; Tsuchida E
Construction of artificial methemoglobin reduction systems in Hb vesicles.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(1-2):31-41.
1997: Sakai H; Takeoka S; Park S I; Kose T; Nishide H; Izumi Y; Yoshizu A; Kobayashi K; Tsuchida E
Surface modification of hemoglobin vesicles with poly(ethylene glycol) and effects on aggregation, viscosity, and blood flow during 90% exchange transfusion in anesthetized rats.
Bioconjugate chemistry 1997;8(1):23-30.
1996: Izumi Y; Sakai H; Hamada K; Takeoka S; Yamahata T; Kato R; Nishide H; Tsuchida E; Kobayashi K
Physiologic responses to exchange transfusion with hemoglobin vesicles as an artificial oxygen carrier in anesthetized rats: changes in mean arterial pressure and renal cortical tissue oxygen tension.
Critical care medicine 1996;24(11):1869-73.
1996: Sakai H; Hamada K; Takeoka S; Nishide H; Tsuchida E
Physical properties of hemoglobin vesicles as red cell substitutes.
Biotechnology progress 1996;12(1):119-25.
1994: Tsuchida E
[Recent progress and trend in the development of artificial blood]
Nippon rinsho. Japanese journal of clinical medicine 1994;52(9):2483-91.
1994: Tsuchida E
[Progress in the red cell substitutes (artificial red cells)]
[Rinsho ketsueki] The Japanese journal of clinical hematology 1994;35(5):439-45.
1994: Tsuchida E; Komatsu T
Synthetic hemes.
Methods in enzymology 1994;231():167-93, 685-7.
1994: Kakizaki T; Kobayashi K; Komatsu T; Nishide H; Tsuchida E
Lipidheme-microsphere (LH-M). A new type of totally synthetic oxygen carrier and its oxygen carrying ability.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):933-8.
1994: Kobayashi K; Kakizaki T; Komatsu T; Nishide H; Tsuchida E
Two types of totally artificial red blood cell substitutes liposome embedded heme(L/H) and lipidheme/microsphere(LHM).
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):895-900.
1994: Takeoka S; Sakai H; Terase K; Nishide H; Tsuchida E
Characteristics of Hb-vesicles and encapsulation procedure.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):861-6.
1994: Komatsu T; Nishide H; Tsuchida E
Structure and solution properties of lipidheme-microsphere.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):855-60.
1994: Sakai H; Takeoka S; Nishide H; Tsuchida E
Convenient method to purify hemoglobin.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):651-6.
1994: Tsuchida E
Stabilized hemoglobin vesicles.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):467-77.
1993: Sakai H; Takeoka S; Yokohama H; Seino Y; Nishide H; Tsuchida E
Purification of concentrated hemoglobin using organic solvent and heat treatment.
Protein expression and purification 1993;4(6):563-9.
1993: Tsuchida E; Nishide H; Hasegawa E; Chika Y; Fukuzumi M; Komatsu T
Synthesis of porphinatoirons having an alkyl amphiphilic chain and their O2 binding properties in lipid bilayers.
Journal of inorganic biochemistry 1993;49(4):255-64.
1992: Tsuchida E; Nishide H; Komatsu T; Yamamoto K; Matsubuchi E; Kobayashi K
Lipid microsphere containing lipophilic heme: preparation and oxygen transportation under physiological conditions.
Biochimica et biophysica acta 1992;1108(2):253-6.
1992: Takeoka S; Hasegawa E; Nishide H; Tsuchida E; Sekiguchi S
Oxygen-transport and solution properties of polylipid/Hb vesicles (ARC).
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):399-404.
1992: Tsuchida E
Synthesis and characterization of artificial red cell (ARC).
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology 1992;20(2-4):337-44.
1991: Kobayashi K; Watanabe M; Ishihara T; Nishide H; Tsuchida E
Liposome-embedded-heme as a totally artificial oxygen carrier.
ASAIO transactions / American Society for Artificial Internal Organs 1991;37(3):M443-4.
1988: Tsuchida E; Nishide H; Ohno H
Liposome/heme as a totally synthetic oxygen carrier.
Biomaterials, artificial cells, and artificial organs 1988;16(1-3):313-9.
1987: Matsushita Y; Eshima K; Shindo T; Yamamoto Y; Hasegawa E; Nishide H; Tsuchida E
Clearance and tissue distribution of functionalized polymeric liposomes from the blood stream of rats.
Biochimica et biophysica acta 1987;901(1):166-71.
1987: Yuasa M; Tani Y; Nishide H; Tsuchida E
Stabilization effect of tocopherol and catalase on the life-time of liposome-embedded heme as an oxygen carrier.
Biochimica et biophysica acta 1987;900(1):160-2.
1986: Hasegawa E; Eshima K; Matsushita Y; Nishide H; Tsuchida E
Interactions of functionalized polymeric liposomes having a porphinato-iron complex with some biological cells and components in vitro.
Biochimica et biophysica acta 1986;862(2):235-42.
1984: Uotani N; Hasegawa E; Nishide H; Tsuchida E
Enzymatic reduction of synthetic polymer-bound hemin derivatives: efficient method to prepare a heme-oxygen adduct in cooled aqueous medium.
Journal of inorganic biochemistry 1984;22(2):85-9.
1983: Tsuchida E; Nishide H; Sekine M; Yamagishi A
Liposomal heme as oxygen carrier under semi-physiological conditions. Orientation study of heme embedded in a phospholipid bilayer by an electrooptical method.
Biochimica et biophysica acta 1983;734(2):274-8.
1982: Tsuchida E; Nishide H; Sekine M; Yuasa M; Iizuka T; Ishimura Y
Oxygen- and carbon monoxide-binding kinetic parameters for liposomal heme under semi-physiological condition.
Biochemical and biophysical research communications 1982;109(3):858-63.

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