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Hideaki Tsuge

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Takashi Kuzuhara; Hideaki Tsuge
[The tertiary structures of the domains of influenza RNA polymerase].
Hideaki Tsuge; Toshiharu Tsurumura; Hiroko Utsunomiya; Daisuke Kise; Takashi Kuzuhara; Tatsuro Watanabe; Hirota Fujiki; Masami Suganuma
Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein.
Takashi Kuzuhara; Daisuke Kise; Hiroko Yoshida; Takahiro Horita; Yoshimi Murazaki; Akie Nishimura; Noriko Echigo; Hiroko Utsunomiya; Hideaki Tsuge
Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue.

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All Publications

2012: Takashi Kuzuhara; Hideaki Tsuge
[The tertiary structures of the domains of influenza RNA polymerase].
Seikagaku. The Journal of Japanese Biochemical Society 2012;84(9):780-5.
2009: Hideaki Tsuge; Toshiharu Tsurumura; Hiroko Utsunomiya; Daisuke Kise; Takashi Kuzuhara; Tatsuro Watanabe; Hirota Fujiki; Masami Suganuma
Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein.
Biochemical and biophysical research communications 2009;388(2):193-8.
2009: Takashi Kuzuhara; Daisuke Kise; Hiroko Yoshida; Takahiro Horita; Yoshimi Murazaki; Akie Nishimura; Noriko Echigo; Hiroko Utsunomiya; Hideaki Tsuge
Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue.
The Journal of biological chemistry 2009;284(11):6855-60.
2008: Haruhiko Sakuraba; Kazunari Yoneda; Kiyo Takeuchi; Hideaki Tsuge; Nobuhiko Katunuma; Toshihisa Ohshima
Structure of an archaeal alanine:glyoxylate aminotransferase.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 6):696-9.
2008: Takahito Imagawa; Hitoshi Iino; Mayumi Kanagawa; Akio Ebihara; Seiki Kuramitsu; Hideaki Tsuge
Crystal structure of the YdjC-family protein TTHB029 from Thermus thermophilus HB8: structural relationship with peptidoglycan N-acetylglucosamine deacetylase.
Biochemical and biophysical research communications 2008;367(3):535-41.
2008: Hitoshi Sakuraba; Kazunari Yoneda; Issaku Asai; Hideaki Tsuge; Nobuhiko Katunuma; Toshihisa Ohshima
Structure of l-aspartate oxidase from the hyperthermophilic archaeon Sulfolobus tokodaii.
Biochimica et biophysica acta 2008;1784(3):563-71.
2007: Hitoshi Sakuraba; Kazunari Yoneda; Kumiko Yoshihara; Kyoko Satoh; Ryushi Kawakami; Yoshihiro Uto; Hideaki Tsuge; Katsuyuki Takahashi; Hitoshi Hori; Toshihisa Ohshima
Sequential aldol condensation catalyzed by hyperthermophilic 2-deoxy-d-ribose-5-phosphate aldolase.
Applied and environmental microbiology 2007;73(22):7427-34.
2007: Tomoya Kawazoe; Hideaki Tsuge; Takahito Imagawa; Kenji Aki; Seiki Kuramitsu; Kiyoshi Fukui
Structural basis of D-DOPA oxidation by D-amino acid oxidase: alternative pathway for dopamine biosynthesis.
Biochemical and biophysical research communications 2007;355(2):385-91.
2007: Hitoshi Nakayama; Tatsuro Shimamura; Takahito Imagawa; Nobuaki Shirai; Takashi Itoh; Yoshihiko Sako; Masashi Miyano; Haruhiko Sakuraba; Toshihisa Ohshima; Norimichi Nomura; Hideaki Tsuge
Structure of a hyperthermophilic archaeal homing endonuclease, I-Tsp061I: contribution of cross-domain polar networks to thermostability.
Journal of molecular biology 2007;365(2):362-78.
2007: Tomoya Kawazoe; Hwan Ki Park; Sanae Iwana; Hideaki Tsuge; Kiyoshi Fukui
Human D-amino acid oxidase: an update and review.
Chemical record (New York, N.Y.) 2007;7(5):305-15.
2006: Tomoya Kawazoe; Hideaki Tsuge; Mirella S Pilone; Kiyoshi Fukui
Crystal structure of human D-amino acid oxidase: context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring.
Protein science : a publication of the Protein Society 2006;15(12):2708-17.
2006: Hideo Ago; Masataka Oda; Masaya Takahashi; Hideaki Tsuge; Sadayuki Ochi; Nobuhiko Katunuma; Masashi Miyano; Jun Sakurai
Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus.
The Journal of biological chemistry 2006;281(23):16157-67.
2006: Hideaki Tsuge; Kenji Aki; Nobuhiko Katanuma; Ryushi Kawakami; Hitoshi Sakuraba; Toshihisa Ohshima
[Novel diflavin-containing dehydrogenase family: FAD, FMN and ATP-containing L-proline dehydrogenase].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(1):41-5.
2005: Hideaki Tsuge; Ryushi Kawakami; Hitoshi Sakuraba; Hideo Ago; Masashi Miyano; Kenji Aki; Nobuhiko Katunuma; Toshihisa Ohshima
Crystal structure of a novel FAD-, FMN-, and ATP-containing L-proline dehydrogenase complex from Pyrococcus horikoshii.
The Journal of biological chemistry 2005;280(35):31045-9.
2005: Ryushi Kawakami; Hitoshi Sakuraba; Hideaki Tsuge; Shuichiro Goda; Nobuhiko Katunuma; Toshihisa Ohshima
A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3.
The FEBS journal 2005;272(16):4044-54.
2005: Hitoshi Sakuraba; Hideaki Tsuge; Kazunari Yoneda; Nobuhiko Katunuma; Toshihisa Ohshima
Crystal structure of the NAD biosynthetic enzyme quinolinate synthase.
The Journal of biological chemistry 2005;280(29):26645-8.
2005: Kazunari Yoneda; Hitoshi Sakuraba; Hideaki Tsuge; Nobuhiko Katunuma; Seiki Kuramitsu; Takeshi Kawabata; Toshihisa Ohshima
The first crystal structure of an archaeal helical repeat protein.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):636-9.
2005: Mohammad W Bhuiya; Hitoshi Sakuraba; Toshihisa Ohshima; Takahito Imagawa; Nobuhiko Katunuma; Hideaki Tsuge
The first crystal structure of hyperthermostable NAD-dependent glutamate dehydrogenase from Pyrobaculum islandicum.
Journal of molecular biology 2005;345(2):325-37.
2004: Takahito Imagawa; Hitoshi Nakayama; Nobuhiko Katunuma; Hitoshi Sakuraba; Toshihisa Ohshima; Takashi Itoh; Yoshihiko Sako; Norimichi Nomura; Hideaki Tsuge
Crystallization and preliminary X-ray diffraction analysis of homing endonuclease I-Tsp061I.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 11):2006-8.
2004: Mohammad W Bhuiya; Hitoshi Sakuraba; Kazunari Yoneda; Toshihisa Ohshima; Takahito Imagawa; Nobuhiko Katunuma; Hideaki Tsuge
Crystallization and preliminary X-ray diffraction analysis of the hyperthermostable NAD-dependent glutamate dehydrogenase from Pyrobaculum islandicum.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 4):715-7.
2003: Hitoshi Sakuraba; Hideaki Tsuge; Ikuko Shimoya; Ryushi Kawakami; Shuichiro Goda; Yutaka Kawarabayasi; Nobuhiko Katunuma; Hideo Ago; Masashi Miyano; Toshihisa Ohshima
The first crystal structure of archaeal aldolase. Unique tetrameric structure of 2-deoxy-d-ribose-5-phosphate aldolase from the hyperthermophilic archaea Aeropyrum pernix.
The Journal of biological chemistry 2003;278(12):10799-806.
2003: Hideaki Tsuge; Masahiro Nagahama; Hiroyuki Nishimura; Junzo Hisatsune; Yoshihiko Sakaguchi; Yasuhiro Itogawa; Nobuhiko Katunuma; Jun Sakurai
Crystal structure and site-directed mutagenesis of enzymatic components from Clostridium perfringens iota-toxin.
Journal of molecular biology 2003;325(3):471-83.
2003: Jun Sakurai; Masahiro Nagahama; Junzo Hisatsune; Nobuhiko Katunuma; Hideaki Tsuge
Clostridium perfringens iota-toxin, ADP-ribosyltransferase: structure and mechanism of action.
Advances in enzyme regulation 2003;43():361-77.
2002: Motohiro Kihara; Hisao Kakegawa; Yuko Matano; Etsuko Murata; Hideaki Tsuge; Hiroshi Kido; Nobuhiko Katunuma
Chondroitin sulfate proteoglycan is a potent enhancer in the processing of procathepsin L.
Biological chemistry 2002;383(12):1925-9.
2002: Hideaki Tsuge; Hitoshi Sakuraba; Toru Kobe; Akira Kujime; Nobuhiko Katunuma; Toshihisa Ohshima
Crystal structure of the ADP-dependent glucokinase from Pyrococcus horikoshii at 2.0-A resolution: a large conformational change in ADP-dependent glucokinase.
Protein science : a publication of the Protein Society 2002;11(10):2456-63.
2002: Mohammad W Bhuiya; Hideaki Tsuge; Hitoshi Sakuraba; Kazunari Yoneda; Nobuhiko Katunuma; Toshihisa Ohshima
Crystallization and preliminary X-ray diffraction analysis of glutamate dehydrogenase from an aerobic hyperthermophilic archaeon, Aeropyrum pernix K1.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 8):1338-9.
2002: Kazunari Yoneda; Tomohiro Nishimura; Nobuhiko Katunuma; Shigeyuki Imamura; Katsutoshi Nitta; Hideaki Tsuge
Crystallization and preliminary X-ray crystallographic studies of monoacylglycerol lipase of the moderately thermophilic Bacillus sp. H-257.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 7):1232-3.
2002: Nobuhiko Katunuma; Hideaki Tsuge; M Nukatsuka; T Asao; M Fukushima
Structure-based design of specific cathepsin inhibitors and their application to protection of bone metastases of cancer cells.
Archives of biochemistry and biophysics 2002;397(2):305-11.
2002: Nobuhiko Katunuma; Hideaki Tsuge; M Nukatsuka; M Fukushima
Structure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis.
Advances in enzyme regulation 2002;42():159-72.
2000: Nobuhiko Katunuma; Hideaki Tsuge; T Asao
[Development of new specific inhibitors for cathepsins and its application for medical field].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(6 Suppl):1057-64.
1999: Hideaki Tsuge; T Nishimura; Y Tada; T Asao; D Turk; V Turk; Nobuhiko Katunuma
Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex.
Biochemical and biophysical research communications 1999;266(2):411-6.
1999: Nobuhiko Katunuma; Etsuko Murata; Hisao Kakegawa; Atsushi Matsui; H Tsuzuki; Hideaki Tsuge; D Turk; V Turk; M Fukushima; Y Tada; T Asao
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo.
FEBS letters 1999;458(1):6-10.
1999: Hideaki Tsuge; Masahiro Nagahama; T Nishimura; Yoshihiko Sakaguchi; Nobuhiko Katunuma; Jun Sakurai
Crystallization and preliminary X-ray studies of the Ia component of Clostridium perfringens iota toxin complexed with NADPH.
Journal of structural biology 1999;126(2):175-7.