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Yoshihide Tsujimoto

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Chemicals & Drugs

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Toshiharu Shibuya; Yoshihide Tsujimoto
Deleterious effects of mitochondrial ROS generated by KillerRed photodynamic action in human cell lines and C. elegans.
Yoshihide Tsujimoto
Multiple ways to die: non-apoptotic forms of cell death.
Goichi Beck; Shinsuke Kato; Saburo Sakoda; Mitsutoshi Setou; Koei Shinzawa; Yuki Sugiura; Yoshihide Tsujimoto; Hisae Sumi-Akamaru
Neuroaxonal dystrophy in calcium-independent phospholipase A2β deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes.

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All Publications

2012: Toshiharu Shibuya; Yoshihide Tsujimoto
Deleterious effects of mitochondrial ROS generated by KillerRed photodynamic action in human cell lines and C. elegans.
Journal of photochemistry and photobiology. B, Biology 2012;117():1-12.
2012: Yoshihide Tsujimoto
Multiple ways to die: non-apoptotic forms of cell death.
Acta oncologica (Stockholm, Sweden) 2012;51(3):293-300.
2011: Goichi Beck; Shinsuke Kato; Saburo Sakoda; Mitsutoshi Setou; Koei Shinzawa; Yuki Sugiura; Yoshihide Tsujimoto; Hisae Sumi-Akamaru
Neuroaxonal dystrophy in calcium-independent phospholipase A2β deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(31):11411-20.
2011: Hayato Hikita; Naoki Hiramatsu; Atsushi Hosui; Hisashi Ishida; Tatsuya Kanto; Takahiro Kodama; Wei Li; Takuya Miyagi; Minoru Shigekawa; Shigeomi Shimizu; S Shimizu; Tetsuo Takehara; Tomohide Tatsumi; Yoshihide Tsujimoto; Norio Hayashi
Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.
Hepatology (Baltimore, Md.) 2011;54(1):240-51.
2010: Hisayo Tsujii; Y Eguchi; Alex Chenchik; Takayuki Mizutani; Kayoko Yamada; Yoshihide Tsujimoto
Screening of cell death genes with a mammalian genome-wide RNAi library.
Journal of biochemistry 2010;148(2):157-70.
2010: Shigeomi Shimizu; Akio Konishi; Y Nishida; T Mizuta; H Nishina; A Yamamoto; Yoshihide Tsujimoto
Involvement of JNK in the regulation of autophagic cell death.
Oncogene 2010;29(14):2070-82.
2010: Kan Ideguchi; Shigeomi Shimizu; Meinoshin Okumura; Yoshihide Tsujimoto
Cyclophilin D-dependent mitochondrial permeability transition is not involved in neurodegeneration in mnd2 mutant mice.
Biochemical and biophysical research communications 2010;393(2):264-7.
2010: Tomonori Aikawa; Koei Shinzawa; Nobuyuki Tanaka; Yoshihide Tsujimoto
Noxa is necessary for hydrogen peroxide-induced caspase-dependent cell death.
FEBS letters 2010;584(4):681-8.
2010: Hidetoshi Hasuwa; Yuko Muro; Masahito Ikawa; Noriko Kato; Yoshihide Tsujimoto; Masaru Okabe
Transgenic mouse sperm that have green acrosome and red mitochondria allow visualization of sperm and their acrosome reaction in vivo.
Experimental animals / Japanese Association for Laboratory Animal Science 2010;59(1):105-7.
2009: Hidehisa Yamagata; Shigeomi Shimizu; Y Nishida; Y Watanabe; W J Craigen; Yoshihide Tsujimoto
Requirement of voltage-dependent anion channel 2 for pro-apoptotic activity of Bax.
Oncogene 2009;28(40):3563-72.
2009: Yuya Nishida; Satoko Arakawa; Kenji Fujitani; Hirofumi Yamaguchi; Takeshi Mizuta; Toku Kanaseki; Masaaki Komatsu; Kinya Otsu; Yoshihide Tsujimoto; Shigeomi Shimizu
Discovery of Atg5/Atg7-independent alternative macroautophagy.
Nature 2009;461(7264):654-8.
2008: Chigure Suzuki; Yoshitaka Isaka; Shigeomi Shimizu; Yoshihide Tsujimoto; Yoshitsugu Takabatake; Takahito Ito; Shiro Takahara; Enyu Imai
Bcl-2 protects tubular epithelial cells from ischemia reperfusion injury by inhibiting apoptosis.
Cell transplantation 2008;17(1-2):223-9.
2007: Takeshi Mizuta; Shigeomi Shimizu; Yousuke Matsuoka; Takashi Nakagawa; Yoshihide Tsujimoto
A Bax/Bak-independent mechanism of cytochrome c release.
The Journal of biological chemistry 2007;282(22):16623-30.
2007: Yoshihide Tsujimoto; Shigeomi Shimizu
Role of the mitochondrial membrane permeability transition in cell death.
Apoptosis : an international journal on programmed cell death 2007;12(5):835-40.
2006: Tsutomu Sasaki; Kazuo Kitagawa; Yoshiki Yagita; Shiro Sugiura; Emi Omura-Matsuoka; Shigeru Tanaka; Kohji Matsushita; Hideyuki Okano; Yoshihide Tsujimoto; Masatsugu Hori
Bcl2 enhances survival of newborn neurons in the normal and ischemic hippocampus.
Journal of neuroscience research 2006;84(6):1187-96.
2006: Yoshihide Tsujimoto; Takashi Nakagawa; Shigeomi Shimizu
Mitochondrial membrane permeability transition and cell death.
Biochimica et biophysica acta 2006;1757(9-10):1297-300.
2006: Ken Ito; Yusuke Oji; Naoya Tatsumi; Shigeomi Shimizu; Y Kanai; Tsutomu Nakazawa; Momotaro Asada; Tanyarat Jomgeow; S Aoyagi; Yoko Nakano; Hiroya Tamaki; Nao Sakaguchi; Toshiaki Shirakata; Sumiyuki Nishida; Manabu Kawakami; Akihiro Tsuboi; Yoshihiro Oka; Yoshihide Tsujimoto; Haruo Sugiyama
Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway.
Oncogene 2006;25(30):4217-29.
2005: Yoshihide Tsujimoto; Shigeomi Shimizu
Another way to die: autophagic programmed cell death.
Cell death and differentiation 2005;12 Suppl 2():1528-34.
2005: Lilin Zhang; Shigeomi Shimizu; Yoshihide Tsujimoto
Two distinct Fas-activated signaling pathways revealed by an antitumor drug D609.
Oncogene 2005;24(18):2954-62.
2005: Takashi Nakagawa; Shigeomi Shimizu; Tetsuya Watanabe; Osamu Yamaguchi; Kinya Otsu; Hirotaka Yamagata; Hidenori Inohara; Takeshi Kubo; Yoshihide Tsujimoto
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.
Nature 2005;434(7033):652-8.
2005: Masamichi Ono; Yoshiki Sawa; Masahiro Ryugo; Alexey N. Aleshin; Shigeomi Shimizu; Rie Sugioka; Yoshihide Tsujimoto; Hikaru Matsuda
BH4 peptide derivative from Bcl-xL attenuates ischemia/reperfusion injury thorough anti-apoptotic mechanism in rat hearts.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;27(1):117-21.
2004: Rie Sugioka; Shigeomi Shimizu; Yoshihide Tsujimoto
Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis.
The Journal of biological chemistry 2004;279(50):52726-34.
2004: Shigeomi Shimizu; Toku Kanaseki; Noboru Mizushima; Takeshi Mizuta; Satoko Arakawa-Kobayashi; Craig Thompson; Yoshihide Tsujimoto
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes.
Nature cell biology 2004;6(12):1221-8.
2004: Lilin Zhang; Shigeomi Shimizu; Kazuhiro Sakamaki; Shin Yonehara; Yoshihide Tsujimoto
A caspase-8-independent signaling pathway activated by Fas ligation leads to exposure of the Bak N terminus.
The Journal of biological chemistry 2004;279(32):33865-74.
2004: Junichi Hitomi; Taiichi Katayama; Yutaka Eguchi; Takashi Kudo; Manabu Taniguchi; Yoshihisa Koyama; Takayuki Manabe; Satoru Yamagishi; Yoshio Bando; Kazunori Imaizumi; Yoshihide Tsujimoto; Masaya Tohyama
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death.
The Journal of cell biology 2004;165(3):347-56.
2003: Koei Shinzawa; Yoshihide Tsujimoto
PLA2 activity is required for nuclear shrinkage in caspase-independent cell death.
The Journal of cell biology 2003;163(6):1219-30.
2003: Rie Sugioka; Shigeomi Shimizu; Toshihiro Funatsu; Hiroshi Tamagawa; Yoshiki Sawa; Toru Kawakami; Yoshihide Tsujimoto
BH4-domain peptide from Bcl-xL exerts anti-apoptotic activity in vivo.
Oncogene 2003;22(52):8432-40.
2003: Akio Konishi; Shigeomi Shimizu; Junko Hirota; Toshifumi Takao; Yuhong Fan; Yosuke Matsuoka; Lilin Zhang; Yoshihiro Yoneda; Yoshitaka Fujii; Arthur I Skoultchi; Yoshihide Tsujimoto
Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks.
Cell 2003;114(6):673-88.
2003: Yoshihide Tsujimoto
Cell death regulation by the Bcl-2 protein family in the mitochondria.
Journal of cellular physiology 2003;195(2):158-67.
2003: Masaya Nomura; Shigeomi Shimizu; Tomoyasu Sugiyama; Masashi Narita; Toshinori Ito; Hikaru Matsuda; Yoshihide Tsujimoto
14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax.
The Journal of biological chemistry 2003;278(3):2058-65.
2002: Tomoyasu Sugiyama; Shigeomi Shimizu; Yosuke Matsuoka; Yoshihiro Yoneda; Yoshihide Tsujimoto
Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim.
Oncogene 2002;21(32):4944-56.
2002: Yoshihide Tsujimoto
Bcl-2 family of proteins: life-or-death switch in mitochondria.
Bioscience reports 2002;22(1):47-58.
2002: Yoshihide Tsujimoto; Shigeomi Shimizu
The voltage-dependent anion channel: an essential player in apoptosis.
Biochimie 2002;84(2-3):187-93.
2001: Shigeomi Shimizu; Yosuke Matsuoka; Y Shinohara; Yoshihiro Yoneda; Yoshihide Tsujimoto
Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells.
The Journal of cell biology 2001;152(2):237-50.
2000: Yoshihide Tsujimoto; Shigeomi Shimizu
VDAC regulation by the Bcl-2 family of proteins.
Cell death and differentiation 2000;7(12):1174-81.
2000: Shinji Tagami; Y Eguchi; M Kinoshita; Masatoshi Takeda; Yoshihide Tsujimoto
A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity.
Oncogene 2000;19(50):5736-46.
2000: H Kusano; Shigeomi Shimizu; Richard C Koya; Hisakazu Fujita; Sayo Kamada; Noboru Kuzumaki; Yoshihide Tsujimoto
Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC.
Oncogene 2000;19(42):4807-14.
2000: Shigeomi Shimizu; Y Shinohara; Yoshihide Tsujimoto
Bax and Bcl-xL independently regulate apoptotic changes of yeast mitochondria that require VDAC but not adenine nucleotide translocator.
Oncogene 2000;19(38):4309-18.
2000: Richard C Koya; Hisakazu Fujita; Shigeomi Shimizu; Makoto Ohtsu; Masato Takimoto; Yoshihide Tsujimoto; Noboru Kuzumaki
Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release.
The Journal of biological chemistry 2000;275(20):15343-9.
2000: Shigeomi Shimizu; T Ide; T Yanagida; Yoshihide Tsujimoto
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.
The Journal of biological chemistry 2000;275(16):12321-5.
2000: K Sato; Y Eguchi; T S Kodama; Yoshihide Tsujimoto
Regions essential for the interaction between Bcl-2 and SMN, the spinal muscular atrophy disease gene product.
Cell death and differentiation 2000;7(4):374-83.
2000: Shigeomi Shimizu; Akio Konishi; T Kodama; Yoshihide Tsujimoto
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3100-5.
2000: Yoshihide Tsujimoto; Shigeomi Shimizu
Bcl-2 family: life-or-death switch.
FEBS letters 2000;466(1):6-10.
2000: Shigeomi Shimizu; Yoshihide Tsujimoto
Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):577-82.
2000: Yoshihide Tsujimoto
Role of anti-apoptotic Bcl-2 protein in spinal muscular atrophy.
Journal of neural transmission. Supplementum 2000;(58):41-52.
1999: J H Lee; Toshifumi Takahashi; Noriko Yasuhara; Johji Inazawa; Sayo Kamada; Yoshihide Tsujimoto
Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.
Oncogene 1999;18(46):6183-90.
1999: S Sahara; M Aoto; Y Eguchi; Naoko Imamoto; Y Yoneda; Yoshihide Tsujimoto
Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation.
Nature 1999;401(6749):168-73.
1999: S Sahara; Y Eguchi; Yoshihide Tsujimoto
[Apoptotic signal transduction from cytosol to nucleus].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(12 Suppl):1907-13.
1999: Tomonari Imazu; Shigeomi Shimizu; Shinji Tagami; M Matsushima; Yusuke Nakamura; Tsuneharu Miki; Akihiko Okuyama; Yoshihide Tsujimoto
Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability.
Oncogene 1999;18(32):4523-9.
1999: Shigeomi Shimizu; M Narita; Yoshihide Tsujimoto
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC.
Nature 1999;399(6735):483-7.
1998: S Okuno; Shigeomi Shimizu; Takashi Ito; Masaya Nomura; E Hamada; Yoshihide Tsujimoto; Hikaru Matsuda
Bcl-2 prevents caspase-independent cell death.
The Journal of biological chemistry 1998;273(51):34272-7.
1998: M Narita; Shigeomi Shimizu; Takashi Ito; Thomas Chittenden; Robert J Lutz; H Matsuda; Yoshihide Tsujimoto
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14681-6.
1998: Yoshihide Tsujimoto
Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(11):697-707.
1998: Sayo Kamada; H Kusano; Hisakazu Fujita; Makoto Ohtsu; Richard C Koya; Noboru Kuzumaki; Yoshihide Tsujimoto
A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8532-7.
1998: H Tanabe; Y Eguchi; Shigeomi Shimizu; J C Martinou; Yoshihide Tsujimoto
Death-signalling cascade in mouse cerebellar granule neurons.
The European journal of neuroscience 1998;10(4):1403-11.
1998: K Kosai; Kunihiro Matsumoto; Satoshi Nagata; Yoshihide Tsujimoto; Tadashi Nakamura
Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor.
Biochemical and biophysical research communications 1998;244(3):683-90.
1998: Shigeomi Shimizu; Y Eguchi; Wataru Kamiike; Y Funahashi; A Mignon; V Lacronique; H Matsuda; Yoshihide Tsujimoto
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1455-9.
1998: K Yamabe; Shigeomi Shimizu; Wataru Kamiike; Satoshi Waguri; Y Eguchi; J Hasegawa; S Okuno; Yasuo Yoshioka; Takashi Ito; Yoshiki Sawa; Yasuo Uchiyama; Yoshihide Tsujimoto; Hikaru Matsuda
Prevention of hypoxic liver cell necrosis by in vivo human bcl-2 gene transfection.
Biochemical and biophysical research communications 1998;243(1):217-23.
1998: Shigeomi Shimizu; Yoshihide Tsujimoto
[Molecular mechanism of apoptosis].
Seikagaku. The Journal of Japanese Biochemical Society 1998;70(1):14-21.
1997: H Iwahashi; Y Eguchi; Noriko Yasuhara; T Hanafusa; Y Matsuzawa; Yoshihide Tsujimoto
Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy.
Nature 1997;390(6658):413-7.
1997: Noriko Yasuhara; S Sahara; Sayo Kamada; Y Eguchi; Yoshihide Tsujimoto
Evidence against a functional site for Bcl-2 downstream of caspase cascade in preventing apoptosis.
Oncogene 1997;15(16):1921-8.
1997: Sayo Kamada; Y Funahashi; Yoshihide Tsujimoto
Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases.
Cell death and differentiation 1997;4(6):473-8.
1997: Yoshihide Tsujimoto
Apoptosis and necrosis: intracellular ATP level as a determinant for cell death modes.
Cell death and differentiation 1997;4(6):429-34.
1997: Ayako Shigenaga; K Kimura; Yoshitaka Kobayakawa; Yoshihide Tsujimoto; Teiichi Tanimura
Cell ablation by ectopic expression of cell death genes, ced-3 and Ice, in Drosophila.
Development, growth & differentiation 1997;39(4):429-36.
1997: Makoto Ohtsu; N Sakai; Hisakazu Fujita; M Kashiwagi; S Gasa; Shigeomi Shimizu; Y Eguchi; Yoshihide Tsujimoto; Y Sakiyama; K Kobayashi; Noboru Kuzumaki
Inhibition of apoptosis by the actin-regulatory protein gelsolin.
The EMBO journal 1997;16(15):4650-6.
1997: Sayo Kamada; M Washida; J Hasegawa; H Kusano; Y Funahashi; Yoshihide Tsujimoto
Involvement of caspase-4(-like) protease in Fas-mediated apoptotic pathway.
Oncogene 1997;15(3):285-90.
1997: Ayako Shigenaga; Y Funahashi; K Kimura; Yoshitaka Kobayakawa; Sayo Kamada; Yoshihide Tsujimoto; Teiichi Tanimura
Targeted expression of ced-3 and Ice induces programmed cell death in Drosophila.
Cell death and differentiation 1997;4(5):371-7.
1997: Yoshihide Tsujimoto
[Regulation of cell death by Bcl-2 family].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1644-8.
1997: Y Eguchi; Shigeomi Shimizu; Yoshihide Tsujimoto
[Molecular biology of apoptosis].
Rinsho byori. The Japanese journal of clinical pathology 1997;45(5):470-6.
1997: Yoshihide Tsujimoto; Shigeomi Shimizu; Y Eguchi; Wataru Kamiike; Hikaru Matsuda
Bcl-2 and Bcl-xL block apoptosis as well as necrosis: possible involvement of common mediators in apoptotic and necrotic signal transduction pathways.
Leukemia 1997;11 Suppl 3():380-2.
1997: H Tanabe; Y Eguchi; Sayo Kamada; J C Martinou; Yoshihide Tsujimoto
Susceptibility of cerebellar granule neurons derived from Bcl-2-deficient and transgenic mice to cell death.
The European journal of neuroscience 1997;9(4):848-56.
1997: T Takahashi; H Honda; H Hirai; Yoshihide Tsujimoto
Overexpressed Bcl-x(L) prevents bacterial superantigen-induced apoptosis of thymocytes in vitro.
Cell death and differentiation 1997;4(2):159-65.
1997: Noriko Yasuhara; Y Eguchi; T Tachibana; Naoko Imamoto; Yoshihiro Yoneda; Yoshihide Tsujimoto
Essential role of active nuclear transport in apoptosis.
Genes to cells : devoted to molecular & cellular mechanisms 1997;2(1):55-64.
1996: Shigeomi Shimizu; Y Eguchi; Wataru Kamiike; Y Akao; H Kosaka; J Hasegawa; H Matsuda; Yoshihide Tsujimoto
Involvement of ICE family proteases in apoptosis induced by reoxygenation of hypoxic hepatocytes.
The American journal of physiology 1996;271(6 Pt 1):G949-58.
1996: N Ishii; Akio Wanaka; K Ohno; K Matsumoto; Y Eguchi; T Mori; Yoshihide Tsujimoto; Masaya Tohyama
Localization of bcl-2, bax, and bcl-x mRNAs in the developing inner ear of the mouse.
Brain research 1996;726(1-2):123-8.
1996: Shigeomi Shimizu; Y Eguchi; Wataru Kamiike; Satoshi Waguri; Yasuo Uchiyama; H Matsuda; Yoshihide Tsujimoto
Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors.
Oncogene 1996;13(1):21-9.
1996: Shigeomi Shimizu; Y Eguchi; Wataru Kamiike; H Matsuda; Yoshihide Tsujimoto
Bcl-2 expression prevents activation of the ICE protease cascade.
Oncogene 1996;12(11):2251-7.
1996: Shigeomi Shimizu; Y Eguchi; Wataru Kamiike; Satoshi Waguri; Yasuo Uchiyama; H Matsuda; Yoshihide Tsujimoto
Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions.
Oncogene 1996;12(10):2045-50.
1996: Hiromi Iwahashi; Toshiaki Hanafusa; Y Eguchi; Hiromu Nakajima; Jun-ichiro Miyagawa; N Itoh; K Tomita; Mitsuyoshi Namba; Masamichi Kuwajima; Toshihide Noguchi; Yoshihide Tsujimoto; Yuji Matsuzawa
Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: inhibition by Bcl-2.
Diabetologia 1996;39(5):530-6.
1996: Shigeomi Shimizu; Y Eguchi; Wataru Kamiike; Y Itoh; J Hasegawa; K Yamabe; Y Otsuki; H Matsuda; Yoshihide Tsujimoto
Induction of apoptosis as well as necrosis by hypoxia and predominant prevention of apoptosis by Bcl-2 and Bcl-XL.
Cancer research 1996;56(9):2161-6.
1996: J Hasegawa; Sayo Kamada; Wataru Kamiike; Shigeomi Shimizu; Tomonari Imazu; H Matsuda; Yoshihide Tsujimoto
Involvement of CPP32/Yama(-like) proteases in Fas-mediated apoptosis.
Cancer research 1996;56(8):1713-8.
1996: Wataru Kamiike; Shigeomi Shimizu; Y Eguchi; J Hasegawa; K Yamabe; S Okuno; Yoshihide Tsujimoto; H Matsuda
Involvement of ICE-like proteases in hypoxic cell death.
Transplantation proceedings 1996;28(2):1106-7.
1996: Keisuke Fukuo; S Hata; T Suhara; T Nakahashi; Y Shinto; Yoshihide Tsujimoto; Shigeto Morimoto; Toshio Ogihara
Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle.
Hypertension 1996;27(3 Pt 2):823-6.
1996: Yoshihide Tsujimoto
bcl-2: antidote for cell death.
Progress in molecular and subcellular biology 1996;16():72-86.
1995: Y Shinto; M Morimoto; M Katsumata; Atsumasa Uchida; Katsuyuki Aozasa; M Okamoto; T Kurosawa; Takahiro Ochi; M I Greene; Yoshihide Tsujimoto
Moloney murine leukemia virus infection accelerates lymphomagenesis in E mu-bcl-2 transgenic mice.
Oncogene 1995;11(9):1729-36.
1995: Shigeomi Shimizu; Y Eguchi; H Kosaka; Wataru Kamiike; H Matsuda; Yoshihide Tsujimoto
Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.
Nature 1995;374(6525):811-3.
1995: Sayo Kamada; A Shimono; Y Shinto; T Tsujimura; T Takahashi; T Noda; Y Kitamura; Hisato Kondoh; Yoshihide Tsujimoto
bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine.
Cancer research 1995;55(2):354-9.
1994: Yoshihide Tsujimoto
[Molecular biology of cell death].
Gan to kagaku ryoho. Cancer & chemotherapy 1994;21(5):591-5.
1993: Yoshihide Tsujimoto
[Tumorigenesis involving bcl-2 gene].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(2):129-33.