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Catherine Botting

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Physiology

Mutagenesis, Site-Directed

Living Beings

Phenomena

Protein Binding

Procedures

Chemicals & Drugs

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Publications

TOP 3
Khadija Shabbiri; Ahmad Adnan; Catherine H Botting; Matthew Fuszard
Charting the cellular and extracellular proteome analysis of Brevibacterium linens DSM 20158 with unsequenced genome by mass spectrometry-driven sequence similarity searches.
Jesko Koehnke; Falk Morawitz; Sally L Shirran; Iain A Smellie; Margaret C M Smith; Andrew F Bent; Catherine H Botting; Matthew A Fuszard; Wael E Houssen; Marcel Jaspars; James H Naismith
An enzymatic route to selenazolines.
Jesko Koehnke; Falk Morawitz; Andrew Bent; Catherine H Botting; Wael E Houssen; Marcel Jaspars; Ada F Nneoyiegbe; Sally Shirran; Margaret C M Smith; Laurent Trembleau; Jeremie Vendome; David Zollman; James H Naismith
The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain.

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All Publications

2013: Khadija Shabbiri; Ahmad Adnan; Catherine H Botting; Matthew Fuszard
Charting the cellular and extracellular proteome analysis of Brevibacterium linens DSM 20158 with unsequenced genome by mass spectrometry-driven sequence similarity searches.
Journal of proteomics 2013;83():99-118.
2013: Jesko Koehnke; Falk Morawitz; Sally L Shirran; Iain A Smellie; Margaret C M Smith; Andrew F Bent; Catherine H Botting; Matthew A Fuszard; Wael E Houssen; Marcel Jaspars; James H Naismith
An enzymatic route to selenazolines.
Chembiochem : a European journal of chemical biology 2013;14(5):564-7.
2012: Jesko Koehnke; Falk Morawitz; Andrew Bent; Catherine H Botting; Wael E Houssen; Marcel Jaspars; Ada F Nneoyiegbe; Sally Shirran; Margaret C M Smith; Laurent Trembleau; Jeremie Vendome; David Zollman; James H Naismith
The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain.
Nature structural & molecular biology 2012;19(8):767-72.
2012: Sonia Paytubi; Catherine H Botting; Shirley Graham; Eugene V Koonin; Huanting Liu; Kira S Makarova; Stephen McMahon; James H Naismith; Malcolm F White
Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):E398-405.
2011: Stefan Schmelz; Lijiang Song; Catherine H Botting; Gregory L Challis; Nadia F Kadi; James H Naismith
Structural basis for acyl acceptor specificity in the achromobactin biosynthetic enzyme AcsD.
Journal of molecular biology 2011;412(3):495-504.
2011: Ian M Overton; Sally Shirran; Geoffrey J Barton; Catherine H Botting; Katherine A Gould; Shirley Graham; Jason Hinds; Peter J Coote
Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus.
BMC systems biology 2011;5():68.
2010: Peter J Deuss; Gina Popa; Catherine H Botting; Wouter Laan; Paul C J Kamer
Highly efficient and site-selective phosphane modification of proteins through hydrazone linkage: development of artificial metalloenzymes.
Angewandte Chemie (International ed. in English) 2010;49(31):5315-7.
2010: Catherine H Botting; Paul Talbot; Sonia Paytubi; Malcolm F White
Extensive lysine methylation in hyperthermophilic crenarchaea: potential implications for protein stability and recombinant enzymes.
Archaea (Vancouver, B.C.) 2010;2010():.
2010: Gu Liu; Catherine H Botting; Kathryn M Evans; Jeffrey A G Walton; Guogang Xu; Alexandra M Z Slawin; Nicholas J Westwood
Optimisation of conoidin A, a peroxiredoxin inhibitor.
ChemMedChem 2010;5(1):41-5.
2009: Nasrin Jahan; Jane A Potter; Md Arif Sheikh; Catherine H Botting; Sally L Shirran; Nicholas J Westwood; Garry L Taylor
Insights into the biosynthesis of the Vibrio cholerae major autoinducer CAI-1 from the crystal structure of the PLP-dependent enzyme CqsA.
Journal of molecular biology 2009;392(3):763-73.
2009: Stefan Schmelz; Nadia Kadi; Stephen McMahon; Lijiang Song; Daniel Oves-Costales; Muse Oke; Huanting Liu; Kenneth Alan Johnson; Lester G Carter; Catherine H Botting; Malcolm White; Gregory L Challis; James H Naismith
AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis.
Nature chemical biology 2009;5(3):174-82.
2009: Ben Hale; Axel Knebel; Catherine H Botting; Caroline S Galloway; BL Precious; David Jackson; Richard M Elliott; Richard E Randall
CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215.
Virology 2009;383(1):6-11.
2008: M Bhattacharjee; Catherine H Botting; M J Sillanpää
Bayesian biomarker identification based on marker-expression proteomics data.
Genomics 2008;92(6):384-92.
2008: Muse Oke; Rosalind Tan Yan Ching; Lester G Carter; Kenneth Alan Johnson; Huanting Liu; Stephen McMahon; Malcolm White; Carlos Bloch; Catherine H Botting; Martin A Walsh; Aishah A Latiff; Malcolm W Kennedy; Alan Cooper; James H Naismith
Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog.
Angewandte Chemie (International ed. in English) 2008;47(41):7853-6.
2008: Hai Deng; Catherine H Botting; John T G Hamilton; Rupert J M Russell; David O'Hagan
S-adenosyl-L-methionine:hydroxide adenosyltransferase: a SAM enzyme.
Angewandte Chemie (International ed. in English) 2008;47(29):5357-61.
2007: Jaldappagari Seetharamappa; Muse Oke; Huanting Liu; Stephen McMahon; Kenneth Alan Johnson; Lester Carter; Mark Dorward; Michal Zawadzki; Ian M Overton; C A Johannes van Niekirk; Shirley Graham; Catherine H Botting; Garry L Taylor; Malcolm White; Geoffrey J Barton; Peter J Coote; James H Naismith
Purification, crystallization and data collection of methicillin-resistant Staphylococcus aureus Sar2676, a pantothenate synthetase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 6):488-91.
2007: Dale T Mackay; Catherine H Botting; Garry L Taylor; Malcolm White
An acetylase with relaxed specificity catalyses protein N-terminal acetylation in Sulfolobus solfataricus.
Molecular microbiology 2007;64(6):1540-8.
2007: Jaldappagari Seetharamappa; Muse Oke; Huanting Liu; Stephen McMahon; Kenneth Alan Johnson; Lester Carter; Mark Dorward; Michal Zawadzki; Ian M Overton; C A Johannes van Niekirk; Shirley Graham; Catherine H Botting; Garry L Taylor; Malcolm White; Geoffrey J Barton; Peter J Coote; James H Naismith
Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 5):452-6.
2007: Richard F Collins; Konstantinos Beis; Changjiang Dong; Catherine H Botting; Catherine McDonnell; Robert C Ford; Bradley R Clarke; Chris Whitfield; James H Naismith
The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2390-5.
2007: Xiao Luo; Uli Schwarz-Linek; Catherine H Botting; Reinhard Hensel; Bettina Siebers; Malcolm White
CC1, a novel crenarchaeal DNA binding protein.
Journal of bacteriology 2007;189(2):403-9.
2005: Vasso Makrantoni; Robin Antrobus; Catherine H Botting; Peter J Coote
Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting.
Yeast (Chichester, England) 2005;22(5):401-14.
2004: Clare L Lawrence; Catherine H Botting; Robin Antrobus; Peter J Coote
Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress.
Molecular and cellular biology 2004;24(8):3307-23.
2003: Heidi M Mendoza; Lin-nan Shen; Catherine H Botting; Alan Lewis; Jingwen Chen; Barbara Ink; Ron Thomas Hay
NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins.
The Journal of biological chemistry 2003;278(28):25637-43.
2002: Catherine H Botting; Nicola E Davidson; D Wynne Griffiths; Richard N Bennett; Nigel P Botting
Analysis of intact glucosinolates by MALDI-TOF mass spectrometry.
Journal of agricultural and food chemistry 2002;50(5):983-8.
2001: Michael H Tatham; Ellis Jaffray; Owen A Vaughan; Joana M P Desterro; Catherine H Botting; James H Naismith; Ron Thomas Hay
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.
The Journal of biological chemistry 2001;276(38):35368-74.
2001: Catherine H Botting; Ron Thomas Hay
Role of conserved residues in the activity of adenovirus preterminal protein.
The Journal of general virology 2001;82(Pt 8):1917-27.
2001: Nathan J Wymer; LV Buchanan; D Henderson; N Mehta; Catherine H Botting; Luka Pocivavsek; Carol A Fierke; Eric J Toone; James H Naismith
Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli.
Structure (London, England : 1993) 2001;9(1):1-9.
2000: Catherine H Botting
The use of the slow crystallisation method to improve matrix-assisted laser desorption/ionisation time-of-flight signals for larger proteins.
Rapid communications in mass spectrometry : RCM 2000;14(21):2030-3.
1999: Catherine H Botting; Ron Thomas Hay
Characterisation of the adenovirus preterminal protein and its interaction with the POU homeodomain of NFIII (Oct-1).
Nucleic acids research 1999;27(13):2799-805.
1999: A M O'Dowd; Catherine H Botting; BL Precious; R Shawcross; Richard E Randall
Novel modifications to the C-terminus of LTB that facilitate site-directed chemical coupling of antigens and the development of LTB as a carrier for mucosal vaccines.
Vaccine 1999;17(11-12):1442-53.
1998: E J Parker; Catherine H Botting; A Webster; Ron Thomas Hay
Adenovirus DNA polymerase: domain organisation and interaction with preterminal protein.
Nucleic acids research 1998;26(5):1240-7.
1996: E A Green; Catherine H Botting; H M Webb; Timothy R Hirst; Richard E Randall
Construction, purification and immunogenicity of antigen-antibody-LTB complexes.
Vaccine 1996;14(10):949-58.
1996: J R Matthews; Catherine H Botting; M Panico; H R Morris; Ron Thomas Hay
Inhibition of NF-kappaB DNA binding by nitric oxide.
Nucleic acids research 1996;24(12):2236-42.
1995: Catherine H Botting; Richard E Randall
Reporter enzyme-nitrilotriacetic acid-nickel conjugates: reagents for detecting histidine-tagged proteins.
BioTechniques 1995;19(3):362-3.
1994: T Hanke; Catherine H Botting; E A Green; P W Szawlowski; Erling Rud; Richard E Randall
Expression and purification of nonglycosylated SIV proteins, and their use in induction and detection of SIV-specific immune responses.
AIDS research and human retroviruses 1994;10(6):665-74.
1994: Richard E Randall; D Young; T Hanke; P Szawlowski; Catherine H Botting
Purification of antibody-antigen complexes containing recombinant SIV proteins: comparison of antigen and antibody-antigen complexes for immune priming.
Vaccine 1994;12(4):351-8.