Cristina Bottino

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Castriconi Roberta; Daga Antonio; Dondero Alessandra; Zona Gianluigi; Poliani Pietro Luigi; Melotti Alice; Griffero Fabrizio; Marubbi Daniela; Spaziante Renato; Bellora Francesca; Moretta Lorenzo; Moretta Alessandro; Corte Giorgio; Bottino Cristina
NK cells recognize and kill human glioblastoma cells with stem cell-like properties.
Della Chiesa Mariella; Romeo Elisa; Falco Michela; Balsamo Mirna; Augugliaro Raffaella; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro; Vitale Massimo
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.
Castriconi Roberta; Dondero Alessandra; Negri Francesca; Bellora Francesca; Nozza Paolo; Carnemolla Barbara; Raso Alessandro; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Both CD133+ and CD133- medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity.

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2009: Castriconi Roberta; Daga Antonio; Dondero Alessandra; Zona Gianluigi; Poliani Pietro Luigi; Melotti Alice; Griffero Fabrizio; Marubbi Daniela; Spaziante Renato; Bellora Francesca; Moretta Lorenzo; Moretta Alessandro; Corte Giorgio; Bottino Cristina
NK cells recognize and kill human glioblastoma cells with stem cell-like properties.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3530-9.
2008: Della Chiesa Mariella; Romeo Elisa; Falco Michela; Balsamo Mirna; Augugliaro Raffaella; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro; Vitale Massimo
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.
European journal of immunology 2008;38(8):2284-9.
2007: Castriconi Roberta; Dondero Alessandra; Negri Francesca; Bellora Francesca; Nozza Paolo; Carnemolla Barbara; Raso Alessandro; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Both CD133+ and CD133- medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity.
European journal of immunology 2007;37(11):3190-6.
2007: Castriconi Roberta; Dondero Alessandra; Cantoni Claudia; Della Chiesa Mariella; Prato Carola; Nanni Marina; Fiorini Maurilia; Notarangelo Lucia; Parolini Silvia; Moretta Lorenzo; Notarangelo Luigi; Moretta Alessandro; Bottino Cristina
Functional characterization of natural killer cells in type I leukocyte adhesion deficiency.
Blood 2007;109(11):4873-81.
2006: Vacca Paola; Pietra Gabriella; Falco Michela; Romeo Elisa; Bottino Cristina; Bellora Francesca; Prefumo Federico; Fulcheri Ezio; Venturini Pier Luigi; Costa Mauro; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function.
Blood 2006;108(13):4078-85.
2006: Pende Daniela; Castriconi Roberta; Romagnani Paola; Spaggiari Grazia Maria; Marcenaro Stefania; Dondero Alessandra; Lazzeri Elena; Lasagni Laura; Martini Stefania; Rivera Paola; Capobianco Andrea; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.
Blood 2006;107(5):2030-6.
2005: Pende Daniela; Bottino Cristina; Castriconi Roberta; Cantoni Claudia; Marcenaro Stefania; Rivera Paola; Spaggiari Grazia M; Dondero Alessandra; Carnemolla Barbara; Reymond Nicolas; Mingari Maria Cristina; Lopez Marc; Moretta Lorenzo; Moretta Alessandro
PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis.
Molecular immunology 2005;42(4):463-9.
2004: Castriconi Roberta; Dondero Alessandra; Corrias Maria Valeria; Lanino Edoardo; Pende Daniela; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro
Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction.
Cancer research 2004;64(24):9180-4.
2004: Castriconi Roberta; Dondero Alessandra; Augugliaro Raffaella; Cantoni Claudia; Carnemolla Barbara; Sementa Angela Rita; Negri Francesca; Conte Romana; Corrias Maria Valeria; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12640-5.
2004: Moretta Alessandro; Bottino Cristina
Commentary: Regulated equilibrium between opposite signals: a general paradigm for T cell function?
European journal of immunology 2004;34(8):2084-8.
2004: Falco Michela; Marcenaro Emanuela; Romeo Elisa; Bellora Francesca; Marras Daniele; Vély Frédéric; Ferracci Géraldine; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells.
European journal of immunology 2004;34(6):1663-72.
2004: Reymond Nicolas; Imbert Anne-Marie; Devilard Elisabeth; Fabre Stéphanie; Chabannon Christian; Xerri Luc; Farnarier Catherine; Cantoni Claudia; Bottino Cristina; Moretta Alessandro; Dubreuil Patrice; Lopez Marc
DNAM-1 and PVR regulate monocyte migration through endothelial junctions.
The Journal of experimental medicine 2004;199(10):1331-41.
2004: André Pascale; Castriconi Roberta; Espéli Marion; Anfossi Nicolas; Juarez Tiffany; Hue Sophie; Conway Holli; Romagné François; Dondero Alessandra; Nanni Marina; Caillat-Zucman Sophie; Raulet David H; Bottino Cristina; Vivier Eric; Moretta Alessandro; Paul Pascale
Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors.
European journal of immunology 2004;34(4):961-71.
2003: Marcenaro Emanuela; Augugliaro Raffaella; Falco Michela; Castriconi Roberta; Parolini Silvia; Sivori Simona; Romeo Elisa; Millo Romano; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro
CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity.
European journal of immunology 2003;33(12):3367-76.
2003: Bottino Cristina; Castriconi Roberta; Pende Daniela; Rivera Paola; Nanni Marina; Carnemolla Barbara; Cantoni Claudia; Grassi Jessica; Marcenaro Stefania; Reymond Nicolas; Vitale Massimo; Moretta Lorenzo; Lopez Marc; Moretta Alessandro
Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule.
The Journal of experimental medicine 2003;198(4):557-67.
2003: Moretta Lorenzo; Mingari Maria Cristina; Bottino Cristina; Pende Daniela; Biassoni Roberto; Moretta Alessandro
Cellular and molecular basis of natural killer and natural killer-like activity.
Immunology letters 2003;88(2):89-93.
2003: Augugliaro Raffaella; Parolini Silvia; Castriconi Roberta; Marcenaro Emanuela; Cantoni Claudia; Nanni Marina; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Selective cross-talk among natural cytotoxicity receptors in human natural killer cells.
European journal of immunology 2003;33(5):1235-41.
2003: Castriconi Roberta; Cantoni Claudia; Della Chiesa Mariella; Vitale Massimo; Marcenaro Emanuela; Conte Romana; Biassoni Roberto; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro
Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4120-5.
2002: Moretta Lorenzo; Biassoni Roberto; Bottino Cristina; Cantoni Claudia; Pende Daniela; Mingari Maria Cristina; Moretta Alessandro
Human NK cells and their receptors.
Microbes and infection / Institut Pasteur 2002;4(15):1539-44.
2002: Moretta Lorenzo; Bottino Cristina; Pende Daniela; Mingari Maria Cristina; Biassoni Roberto; Moretta Alessandro
Human natural killer cells: their origin, receptors and function.
European journal of immunology 2002;32(5):1205-11.
2002: Sivori Simona; Falco Michela; Marcenaro Emanuela; Parolini Silvia; Biassoni Roberto; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4526-31.
2002: Vitale Massimo; Zimmer Jacques; Castriconi Roberta; Hanau Daniel; Donato Lionel; Bottino Cristina; Moretta Lorenzo; de la Salle Henri; Moretta Alessandro
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells.
Blood 2002;99(5):1723-9.
2002: Biassoni Roberto; Bottino Cristina; Cantoni Claudia; Moretta Alessandro
Human natural killer receptors and their ligands.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2002;Chapter 14():Unit 14.10.
2002: Moretta Alessandro; Bottino Cristina; Mingari Maria Cristina; Biassoni Roberto; Moretta Lorenzo
What is a natural killer cell?
Nature immunology 2002;3(1):6-8.
2001: Moretta A; Bottino C; Parolini S; Moretta L; Biassoni R; Notarangelo L D
Cellular and molecular pathogenesis of X-linked lymphoproliferative disease.
Current opinion in allergy and clinical immunology 2001;1(6):513-7.
2001: Moretta A; Bottino C; Sivori S; Marcenaro E; Castriconi R; Della Chiesa M; Carlomagno S; Augugliaro R; Nanni M; Vitale M; Millo R
Natural killer lymphocytes: "null cells" no more.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2001;106(4):335-42.
2001: Bottino C; Falco M; Parolini S; Marcenaro E; Augugliaro R; Sivori S; Landi E; Biassoni R; Notarangelo L D; Moretta L; Moretta A
NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease.
The Journal of experimental medicine 2001;194(3):235-46.
2001: Biassoni R; Cantoni C; Pende D; Sivori S; Parolini S; Vitale M; Bottino C; Moretta A
Human natural killer cell receptors and co-receptors.
Immunological reviews 2001;181():203-14.
2001: Pende D; Cantoni C; Rivera P; Vitale M; Castriconi R; Marcenaro S; Nanni M; Biassoni R; Bottino C; Moretta A; Moretta L
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin.
European journal of immunology 2001;31(4):1076-86.
2001: Vitale M; Falco M; Castriconi R; Parolini S; Zambello R; Semenzato G; Biassoni R; Bottino C; Moretta L; Moretta A
Identification of NKp80, a novel triggering molecule expressed by human NK cells.
European journal of immunology 2001;31(1):233-42.
2001: Bottino C; Parolini S; Biassoni R; Falco M; Notarangelo L; Moretta A
X-linked lymphoproliferative disease: the dark side of 2b4 function.
Advances in experimental medicine and biology 2001;495():63-7.
2001: Moretta A; Bottino C; Vitale M; Pende D; Cantoni C; Mingari M C; Biassoni R; Moretta L
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.
Annual review of immunology 2001;19():197-223.
2000: Biassoni R; Cantoni C; Falco M; Pende D; Millo R; Moretta L; Bottino C; Moretta A
Human natural killer cell activating receptors.
Molecular immunology 2000;37(17):1015-24.
2000: Bottino C; Augugliaro R; Castriconi R; Nanni M; Biassoni R; Moretta L; Moretta A
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells.
European journal of immunology 2000;30(12):3718-22.
2000: Bottino C; Falco M; Sivori S; Moretta L; Moretta A; Biassoni R
Identification and molecular characterization of a natural mutant of the p50.2/KIR2DS2 activating NK receptor that fails to mediate NK cell triggering.
European journal of immunology 2000;30(12):3569-74.
2000: Sivori S; Parolini S; Marcenaro E; Millo R; Bottino C; Moretta A
Triggering receptors involved in natural killer cell-mediated cytotoxicity against choriocarcinoma cell lines.
Human immunology 2000;61(11):1055-8.
2000: Moretta L; Biassoni R; Bottino C; Mingari M C; Moretta A
Human NK-cell receptors.
Immunology today 2000;21(9):420-2.
2000: Parolini S; Bottino C; Falco M; Augugliaro R; Giliani S; Franceschini R; Ochs H D; Wolf H; Bonnefoy J Y; Biassoni R; Moretta L; Notarangelo L D; Moretta A
X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells.
The Journal of experimental medicine 2000;192(3):337-46.
2000: Moretta A; Biassoni R; Bottino C; Mingari M C; Moretta L
Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis.
Immunology today 2000;21(5):228-34.
2000: Sivori S; Parolini S; Falco M; Marcenaro E; Biassoni R; Bottino C; Moretta L; Moretta A
2B4 functions as a co-receptor in human NK cell activation.
European journal of immunology 2000;30(3):787-93.
2000: Bottino C; Biassoni R; Millo R; Moretta L; Moretta A
The human natural cytotoxicity receptors (NCR) that induce HLA class I-independent NK cell triggering.
Human immunology 2000;61(1):1-6.
1999: Pende D; Parolini S; Pessino A; Sivori S; Augugliaro R; Morelli L; Marcenaro E; Accame L; Malaspina A; Biassoni R; Bottino C; Moretta L; Moretta A
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells.
The Journal of experimental medicine 1999;190(10):1505-16.
1999: Cantoni C; Bottino C; Augugliaro R; Morelli L; Marcenaro E; Castriconi R; Vitale M; Pende D; Sivori S; Millo R; Biassoni R; Moretta L; Moretta A
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells.
European journal of immunology 1999;29(10):3148-59.
1999: Falco M; Biassoni R; Bottino C; Vitale M; Sivori S; Augugliaro R; Moretta L; Moretta A
Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells.
The Journal of experimental medicine 1999;190(6):793-802.
1999: Falco M; Cantoni C; Bottino C; Moretta A; Biassoni R
Identification of the rat homologue of the human NKp46 triggering receptor.
Immunology letters 1999;68(2-3):411-4.
1999: Sivori S; Pende D; Bottino C; Marcenaro E; Pessino A; Biassoni R; Moretta L; Moretta A
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells.
European journal of immunology 1999;29(5):1656-66.
1999: Biassoni R; Pessino A; Bottino C; Pende D; Moretta L; Moretta A
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity.
European journal of immunology 1999;29(3):1014-20.
1999: Cantoni C; Bottino C; Vitale M; Pessino A; Augugliaro R; Malaspina A; Parolini S; Moretta L; Moretta A; Biassoni R
NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily.
The Journal of experimental medicine 1999;189(5):787-96.
1999: Biassoni R; Bottino C; Millo R; Moretta L; Moretta A
Natural killer cell-mediated recognition of human trophoblast.
Seminars in cancer biology 1999;9(1):13-8.
1999: Moretta A; Bottino C; Millo R; Biassoni R
HLA-specific and non-HLA-specific human NK receptors.
Current topics in microbiology and immunology 1999;244():69-84.
1998: Pessino A; Sivori S; Bottino C; Malaspina A; Morelli L; Moretta L; Biassoni R; Moretta A
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity.
The Journal of experimental medicine 1998;188(5):953-60.
1998: Vitale M; Bottino C; Sivori S; Sanseverino L; Castriconi R; Marcenaro E; Augugliaro R; Moretta L; Moretta A
NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis.
The Journal of experimental medicine 1998;187(12):2065-72.
1998: Cantoni C; Biassoni R; Pende D; Sivori S; Accame L; Pareti L; Semenzato G; Moretta L; Moretta A; Bottino C
The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-C gene.
European journal of immunology 1998;28(1):327-38.
1997: Moretta A; Parolini S; Castriconi R; Bottino C; Vitale M; Sivori S; Millo R
Function and specificity of human natural killer cell receptors.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1997;24(6):455-68.
1997: Biassoni R; Pessino A; Malaspina A; Cantoni C; Bottino C; Sivori S; Moretta L; Moretta A
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules.
European journal of immunology 1997;27(12):3095-9.
1997: Sivori S; Vitale M; Morelli L; Sanseverino L; Augugliaro R; Bottino C; Moretta L; Moretta A
p46, a novel natural killer cell-specific surface molecule that mediates cell activation.
The Journal of experimental medicine 1997;186(7):1129-36.
1997: Moretta A; Biassoni R; Bottino C; Pende D; Vitale M; Poggi A; Mingari M C; Moretta L
Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes.
Immunological reviews 1997;155():105-17.
1996: Sivori S; Vitale M; Sanseverino L; Parolini S; Barbaresi M; Bottino C; Moretta A
Inhibitory CD94 molecules identified by the Z199 monoclonal antibody recognize different HLA-class I molecules.
Transplantation proceedings 1996;28(6):3199-203.
1996: Sivori S; Vitale M; Bottino C; Marcenaro E; Sanseverino L; Parolini S; Moretta L; Moretta A
CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies.
European journal of immunology 1996;26(10):2487-92.
1996: Moretta L; Mingari M C; Pende D; Bottino C; Biassoni R; Moretta A
The molecular basis of natural killer (NK) cell recognition and function.
Journal of clinical immunology 1996;16(5):243-53.
1996: Bottino C; Sivori S; Vitale M; Cantoni C; Falco M; Pende D; Morelli L; Augugliaro R; Semenzato G; Biassoni R; Moretta L; Moretta A
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.
European journal of immunology 1996;26(8):1816-24.
1996: Pende D; Biassoni R; Cantoni C; Verdiani S; Falco M; di Donato C; Accame L; Bottino C; Moretta A; Moretta L
The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.
The Journal of experimental medicine 1996;184(2):505-18.
1996: Vitale M; Sivori S; Pende D; Augugliaro R; Di Donato C; Amoroso A; Malnati M; Bottino C; Moretta L; Moretta A
Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1453-7.
1996: Biassoni R; Cantoni C; Falco M; Verdiani S; Bottino C; Vitale M; Conte R; Poggi A; Moretta A; Moretta L
The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.
The Journal of experimental medicine 1996;183(2):645-50.
1996: Moretta A; Vitale M; Sivori S; Morelli L; Pende D; Bottino C
Inhibitory and activatory receptors for HLA class I molecules in human natural killer cells.
Chemical immunology 1996;64():77-87.
1995: Moretta A; Sivori S; Vitale M; Pende D; Morelli L; Augugliaro R; Bottino C; Moretta L
Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.
The Journal of experimental medicine 1995;182(3):875-84.
1995: Wagtmann N; Biassoni R; Cantoni C; Verdiani S; Malnati M S; Vitale M; Bottino C; Moretta L; Moretta A; Long E O
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.
Immunity 1995;2(5):439-49.
1994: Bottino C; Vitale M; Olcese L; Sivori S; Morelli L; Augugliaro R; Ciccone E; Moretta L; Moretta A
The human natural killer cell receptor for major histocompatibility complex class I molecules. Surface modulation of p58 molecules and their linkage to CD3 zeta chain, Fc epsilon RI gamma chain and the p56lck kinase.
European journal of immunology 1994;24(10):2527-34.
1994: Moretta A; Vitale M; Sivori S; Bottino C; Morelli L; Augugliaro R; Barbaresi M; Pende D; Ciccone E; Lopez-Botet M; Moretta L
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.
The Journal of experimental medicine 1994;180(2):545-55.
1994: Ciccone E; Pende D; Vitale M; Nanni L; Di Donato C; Bottino C; Morelli L; Viale O; Amoroso A; Moretta A
Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells.
European journal of immunology 1994;24(4):1003-6.
1994: Vitale M; Sivori S; Sanseverino L; Barbaresi M; Morelli L; Olcese L; Agugliano R; Bottino C; Moretta A
Negative signalling via the P58/NKR for HLA.C alleles.
European journal of histochemistry : EJH 1994;38 Suppl 1():69-76.
1993: Moretta A; Vitale M; Bottino C; Orengo A M; Morelli L; Augugliaro R; Barbaresi M; Ciccone E; Moretta L
P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.
The Journal of experimental medicine 1993;178(2):597-604.
1993: Tripodi G; Poggi A; Orengo A M; Pella N; Vitale M; Sivori S; Bottino C; Morelli L; Barbaresi M; Revello V
Identification of a new surface molecule involved in the mechanism of cell to cell adhesion between human NK and tumor target cells.
Cytotechnology 1993;11 Suppl 1():S109-11.
1992: Moretta L; Ciccone E; Pende D; Tripodi G; Bottino C; Moretta A
Human natural killer cells: clonally distributed specific functions and triggering surface molecules.
Laboratory investigation; a journal of technical methods and pathology 1992;66(2):138-42.
1992: Moretta A; Bottino C; Tripodi G; Vitale M; Pende D; Morelli L; Augugliaro R; Barbaresi M; Ciccone E; Millo R
Novel surface molecules involved in human NK cell activation and triggering of the lytic machinery.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1992;7():6-10.
1991: Moretta A; Poggi A; Pende D; Tripodi G; Orengo A M; Pella N; Augugliaro R; Bottino C; Ciccone E; Moretta L
CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.
The Journal of experimental medicine 1991;174(6):1393-8.
1991: Ferrini S; Cantoni C; Ciccone E; Biassoni R; Prigione I; Bottino C; Venzano P; Moretta L
A novel surface molecule expressed by long-term cultured T and natural killer cells is involved in cell activation.
European journal of immunology 1991;21(9):1981-7.
1991: Moretta L; Ciccone E; Ferrini S; Pelicci P G; Mingari M C; Zeromski J; Bottino C; Grossi C; Moretta A
Molecular and cellular analysis of human T lymphocytes expressing gamma delta T-cell receptor.
Immunological reviews 1991;120():117-35.
1990: Moretta A; Bottino C; Pende D; Tripodi G; Tambussi G; Viale O; Orengo A; Barbaresi M; Merli A; Ciccone E
Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.
The Journal of experimental medicine 1990;172(6):1589-98.
1990: Moretta A; Bottino C; Pende D; Tripodi G; Orengo A M; Millo R; Pelicci P G; Ciccone E; Moretta L
Human T lymphocytes expressing TCR gamma/delta.
Research in immunology 1990;141(7):630-5.
1990: Moretta A; Tambussi G; Bottino C; Tripodi G; Merli A; Ciccone E; Pantaleo G; Moretta L
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.
The Journal of experimental medicine 1990;171(3):695-714.
1989: Moretta A; Ciccone E; Pantaleo G; Tambussi G; Bottino C; Melioli G; Mingari M C; Moretta L
Surface molecules involved in the activation and regulation of T or natural killer lymphocytes in humans.
Immunological reviews 1989;111():145-75.
1989: Moretta L; Ciccone E; Mingari M C; Zeromski J; Bottino C; Ferrini S; Tambussi G; Melioli G; Grossi C E; Moretta A
Phenotypic and functional characterization of human T lymphocytes expressing a gamma/delta T cell antigen receptor.
Clinical and experimental rheumatology 1989;7 Suppl 3():S9-14.
1989: Grossi C E; Ciccone E; Migone N; Bottino C; Zarcone D; Mingari M C; Ferrini S; Tambussi G; Viale O; Casorati G
Human T cells expressing the gamma/delta T-cell receptor (TcR-1): C gamma 1- and C gamma 2-encoded forms of the receptor correlate with distinctive morphology, cytoskeletal organization, and growth characteristics.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(5):1619-23.
1989: Ferrini S; Prigione I; Bottino C; Ciccone E; Tambussi G; Mammoliti S; Moretta L; Moretta A
Monoclonal antibodies which react with the T cell receptor gamma/delta recognize different subsets of CD3+WT31- T lymphocytes.
European journal of immunology 1989;19(1):57-61.
1989: Mingari M C; Tambussi G; Bottino C; Varese P; Moretta A
Partial inefficiency of T cell receptors gamma/delta composed of a heavy (55-kD) gamma chain to mediate cell activation upon binding to specific monoclonal antibodies.
La Ricerca in clinica e in laboratorio 1989;19(1):39-44.
1989: Moretta L; Ciccone E; Mingari M C; Bottino C; Ferrini S; Tambussi G; Melioli G; Grossi C E; Moretta A
Human T lymphocytes expressing gamma/delta T cell antigen receptor.
Clinical immunology and immunopathology 1989;50(1 Pt 2):S117-23.
1989: Mingari M C; Varese P; Bottino C; Tambussi G; Moretta L
Human thymocytes expressing gamma/delta T-cell receptors.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():39-42.
1989: Moretta A; Ciccone E; Tambussi G; Bottino C; Viale O; Pende D; Santoni A; Mingari M C
Surface molecules involved in CD3-negative NK cell function. A novel molecule which regulates the activation of a subset of human NK cells.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():48-52.
1988: Moretta A; Bottino C; Ciccone E; Tambussi G; Mingari M C; Ferrini S; Casorati G; Varese P; Viale O; Migone N
Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain.
The Journal of experimental medicine 1988;168(6):2349-54.
1988: Mingari M C; Varese P; Bottino C; Melioli G; Moretta A; Moretta L
Clonal analysis of CD4-CD8- human thymocytes expressing a T cell receptor gamma/delta chain. Direct evidence for the de novo expression of CD8 surface antigen and of cytolytic activity against tumor targets.
European journal of immunology 1988;18(11):1831-4.
1988: Bottino C; Tambussi G; Ferrini S; Ciccone E; Varese P; Mingari M C; Moretta L; Moretta A
Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.
The Journal of experimental medicine 1988;168(2):491-505.
1988: Pantaleo G; Zocchi M R; Ferrini S; Poggi A; Tambussi G; Bottino C; Moretta L; Moretta A
Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction.
The Journal of experimental medicine 1988;168(1):13-24.
1988: Ciccone E; Ferrini S; Bottino C; Viale O; Prigione I; Pantaleo G; Tambussi G; Moretta A; Moretta L
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).
The Journal of experimental medicine 1988;168(1):1-11.
1988: Ciccone E; Viale O; Bottino C; Pende D; Migone N; Casorati G; Tambussi G; Moretta A; Moretta L
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture.
The Journal of experimental medicine 1988;167(4):1517-22.
1988: Mingari M C; Varese P; Bottino C; Merli A; Moretta L
Interleukin-2-induced proliferation of CD4-CD8- human thymocytes. In vitro expression of CD3 and CD8 antigens and cytolytic activity.
La Ricerca in clinica e in laboratorio 1988;18(1):67-73.
1987: De Maria A; Malnati M; Moretta A; Pende D; Bottino C; Casorati G; Cottafava F; Melioli G; Mingari M C; Migone N
CD3+4-8-WT31-(T cell receptor gamma+) cells and other unusual phenotypes are frequently detected among spontaneously interleukin 2-responsive T lymphocytes present in the joint fluid in juvenile rheumatoid arthritis. A clonal analysis.
European journal of immunology 1987;17(12):1815-9.
1987: Pantaleo G; Ferrini S; Zocchi M R; Bottino C; Biassoni R; Moretta L; Moretta A
Analysis of signal transducing mechanisms in CD3+ CD4- CD8- cells expressing the putative T cell receptor gamma gene product.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(11):3580-4.
1987: Mingari M C; Ferrini S; Pende D; Bottino C; Prigione I; Moretta A; Moretta L
Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2.
International journal of cancer. Journal international du cancer 1987;40(4):495-8.
1987: Moretta L; Pende D; Bottino C; Migone N; Ciccone E; Ferrini S; Mingari M C; Moretta A
Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis.
European journal of immunology 1987;17(9):1229-34.
1987: Bottino C; Ferrini S; Ciccone E; Prigione I; Pende D; Mingari M C; Moretta L; Moretta A
Analysis of CD3-associated molecules in CD4- 8- human T cell clones lacking the typical alpha/beta T cell receptor.
La Ricerca in clinica e in laboratorio 1987;17(2):125-9.

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