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Shoichiro Tsukita

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Tsukita Sachiko; Katsuno Tatsuya; Yamazaki Yuji; Umeda Kazuaki; Tamura Atsushi; Tsukita Shoichiro
Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.
Adachi Makoto; Hamazaki Yoko; Kobayashi Yuka; Itoh Masahiko; Tsukita Sachiko; Furuse Mikio; Tsukita Shoichiro
Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.
Takahashi Senye; Iwamoto Noriko; Sasaki Hiroyuki; Ohashi Masato; Oda Yukako; Tsukita Shoichiro; Furuse Mikio
The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells.

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All Publications

2009: Tsukita Sachiko; Katsuno Tatsuya; Yamazaki Yuji; Umeda Kazuaki; Tamura Atsushi; Tsukita Shoichiro
Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.
Annals of the New York Academy of Sciences 2009;1165():44-52.
2009: Adachi Makoto; Hamazaki Yoko; Kobayashi Yuka; Itoh Masahiko; Tsukita Sachiko; Furuse Mikio; Tsukita Shoichiro
Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.
Molecular and cellular biology 2009;29(9):2372-89.
2009: Takahashi Senye; Iwamoto Noriko; Sasaki Hiroyuki; Ohashi Masato; Oda Yukako; Tsukita Shoichiro; Furuse Mikio
The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells.
Journal of cell science 2009;122(Pt 7):985-94.
2009: Miyamoto Tatsuo; Momoi Akihiro; Kato Keitaro; Kondoh Hisato; Tsukita Shoichiro; Furuse Mikio; Furutani-Seiki Makoto
Generation of transgenic medaka expressing claudin7-EGFP for imaging of tight junctions in living medaka embryos.
Cell and tissue research 2009;335(2):465-71.
2008: Kubo Akiharu; Yuba-Kubo Akiko; Tsukita Sachiko; Tsukita Shoichiro; Amagai Masayuki
Sentan: a novel specific component of the apical structure of vertebrate motile cilia.
Molecular biology of the cell 2008;19(12):5338-46.
2008: Tsukita S; Yamazaki Y; Katsuno T; Tamura A; Tsukita S
Tight junction-based epithelial microenvironment and cell proliferation.
Oncogene 2008;27(55):6930-8.
2008: Ikenouchi Junichi; Sasaki Hiroyuki; Tsukita Sachiko; Furuse Mikio; Tsukita Shoichiro
Loss of occludin affects tricellular localization of tricellulin.
Molecular biology of the cell 2008;19(11):4687-93.
2008: Yamazaki Yuji; Umeda Kazuaki; Wada Masami; Nada Shigeyuki; Okada Masato; Tsukita Shoichiro; Tsukita Sachiko
ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens.
Molecular biology of the cell 2008;19(9):3801-11.
2008: Nojima Hisashi; Adachi Makoto; Matsui Takeshi; Okawa Katsuya; Tsukita Shoichiro; Tsukita Sachiko
IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.
Nature cell biology 2008;10(8):971-8.
2008: Katsuno Tatsuya; Umeda Kazuaki; Matsui Takeshi; Hata Masaki; Tamura Atsushi; Itoh Masahiko; Takeuchi Kosei; Fujimori Toshihiko; Nabeshima Yo-ichi; Noda Tetsuo; Tsukita Shoichiro; Tsukita Sachiko
Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells.
Molecular biology of the cell 2008;19(6):2465-75.
2008: Yamazaki Yuji; Okawa Katsuya; Yano Tomoki; Tsukita Shoichiro; Tsukita Sachiko
Optimized proteomic analysis on gels of cell-cell adhering junctional membrane proteins.
Biochemistry 2008;47(19):5378-86.
2008: Matsuda Miho; Kobayashi Yuka; Masuda Sayuri; Adachi Makoto; Watanabe Tsuyoshi; Yamashita Jun K; Nishi Eiichiro; Tsukita Shoichiro; Furuse Mikio
Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning.
Experimental cell research 2008;314(5):939-49.
2008: Tamura Atsushi; Kitano Yuka; Hata Masaki; Katsuno Tatsuya; Moriwaki Kazumasa; Sasaki Hiroyuki; Hayashi Hisayoshi; Suzuki Yuichi; Noda Tetsuo; Furuse Mikio; Tsukita Shoichiro; Tsukita Sachiko
Megaintestine in claudin-15-deficient mice.
Gastroenterology 2008;134(2):523-34.
2008: Tamura Atsushi; Kitano Yuka; Hata Masaki; Katsuno Tatsuya; Moriwaki Kazumasa; Sasaki Hiroyuki; Hayashi Hisayoshi; Suzuki Yuichi; Noda Tetsuo; Furuse Mikio; Tsukita Shoichiro; Tsukita Sachiko
Megaintestine in claudin-15-deficient mice.
Gastroenterology 2008;134(2):523-34.
2007: Moriwaki Kazumasa; Tsukita Shoichiro; Furuse Mikio
Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.
Developmental biology 2007;312(2):509-22.
2007: Yamane Junko; Kubo Akiharu; Nakayama Kazuhisa; Yuba-Kubo Akiko; Katsuno Tatsuya; Tsukita Shoichiro; Tsukita Sachiko
Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.
Experimental cell research 2007;313(16):3472-85.
2007: Yamane Junko; Kubo Akiharu; Nakayama Kazuhisa; Yuba-Kubo Akiko; Katsuno Tatsuya; Tsukita Shoichiro; Tsukita Sachiko
Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.
Experimental cell research 2007;313(16):3472-85.
2007: Sugihara-Mizuno Yuko; Adachi Makoto; Kobayashi Yuka; Hamazaki Yoko; Nishimura Miyuki; Imai Toshio; Furuse Mikio; Tsukita Shoichiro
Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(4):473-86.
2007: Ikenouchi Junichi; Umeda Kazuaki; Tsukita Sachiko; Furuse Mikio; Tsukita Shoichiro
Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization.
The Journal of cell biology 2007;176(6):779-86.
2007: Ikenouchi Junichi; Umeda Kazuaki; Tsukita Sachiko; Furuse Mikio; Tsukita Shoichiro
Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization.
The Journal of cell biology 2007;176(6):779-86.
2007: Fukumoto Kanehisa; Kikuchi Shojiro; Itoh Norio; Tamura Atsushi; Hata Masaki; Yamagishi Hisakazu; Tsukita Shoichiro; Tsukita Sachiko
Effects of genetic backgrounds on hyperbilirubinemia in radixin-deficient mice due to different expression levels of Mrp3.
Biochimica et biophysica acta 2007;1772(3):298-306.
2007: Fukumoto Kanehisa; Kikuchi Shojiro; Itoh Norio; Tamura Atsushi; Hata Masaki; Yamagishi Hisakazu; Tsukita Shoichiro; Tsukita Sachiko
Effects of genetic backgrounds on hyperbilirubinemia in radixin-deficient mice due to different expression levels of Mrp3.
Biochimica et biophysica acta 2007;1772(3):298-306.
2007: Mimori-Kiyosue Yuko; Matsui Chiyuki; Sasaki Hiroyuki; Tsukita Shoichiro
Adenomatous polyposis coli (APC) protein regulates epithelial cell migration and morphogenesis via PDZ domain-based interactions with plasma membranes.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(2):219-33.
2006: Adachi Makoto; Inoko Akihito; Hata Masaki; Furuse Kyoko; Umeda Kazuaki; Itoh Masahiko; Tsukita Shoichiro
Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein.
Molecular and cellular biology 2006;26(23):9003-15.
2006: Matsui Takeshi; Kinoshita-Ida Yoko; Hayashi-Kisumi Fumie; Hata Masaki; Matsubara Kaho; Chiba Megumi; Katahira-Tayama Sayaka; Morita Kazumasa; Miyachi Yoshiki; Tsukita Shoichiro
Mouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formation.
The Journal of biological chemistry 2006;281(37):27512-25.
2006: Umeda Kazuaki; Ikenouchi Junichi; Katahira-Tayama Sayaka; Furuse Kyoko; Sasaki Hiroyuki; Nakayama Mayumi; Matsui Takeshi; Tsukita Sachiko; Furuse Mikio; Tsukita Shoichiro
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.
Cell 2006;126(4):741-54.
2006: Umeda Kazuaki; Ikenouchi Junichi; Katahira-Tayama Sayaka; Furuse Kyoko; Sasaki Hiroyuki; Nakayama Mayumi; Matsui Takeshi; Tsukita Sachiko; Furuse Mikio; Tsukita Shoichiro
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.
Cell 2006;126(4):741-54.
2006: Mimori-Kiyosue Yuko; Grigoriev Ilya; Sasaki Hiroyuki; Matsui Chiyuki; Akhmanova Anna; Tsukita Shoichiro; Vorobjev Ivan
Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(8):845-57.
2006: Furuse Mikio; Tsukita Shoichiro
Claudins in occluding junctions of humans and flies.
Trends in cell biology 2006;16(4):181-8.
2006: Loebrich Sven; Bähring Robert; Katsuno Tatsuya; Tsukita Sachiko; Kneussel Matthias
Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton.
The EMBO journal 2006;25(5):987-99.
2006: Shirasaki Yoshitaka; Tanaka Jyunichi; Makazu Hiroshi; Tashiro Koichiro; Shoji Shuichi; Tsukita Shoichiro; Funatsu Takashi
On-chip cell sorting system using laser-induced heating of a thermoreversible gelation polymer to control flow.
Analytical chemistry 2006;78(3):695-701.
2005: Ikenouchi Junichi; Furuse Mikio; Furuse Kyoko; Sasaki Hiroyuki; Tsukita Sachiko; Tsukita Shoichiro
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.
The Journal of cell biology 2005;171(6):939-45.
2005: Ikenouchi Junichi; Furuse Mikio; Furuse Kyoko; Sasaki Hiroyuki; Tsukita Sachiko; Tsukita Shoichiro
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.
The Journal of cell biology 2005;171(6):939-45.
2005: Komiya Satoshi; Shimizu Masayuki; Ikenouchi Junichi; Yonemura Shigenobu; Matsui Takeshi; Fukunaga Yoshitaka; Liu Huijie; Endo Fumio; Tsukita Shoichiro; Nagafuchi Akira
Apical membrane and junctional complex formation during simple epithelial cell differentiation of F9 cells.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(11):1065-80.
2005: Yuba-Kubo Akiko; Kubo Akiharu; Hata Masaki; Tsukita Shoichiro
Gene knockout analysis of two gamma-tubulin isoforms in mice.
Developmental biology 2005;282(2):361-73.
2005: Miyamoto Tatsuo; Morita Kazumasa; Takemoto Daisuke; Takeuchi Kosei; Kitano Yuka; Miyakawa Tsuyoshi; Nakayama Kiyomi; Okamura Yasushi; Sasaki Hiroyuki; Miyachi Yoshiki; Furuse Mikio; Tsukita Shoichiro
Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice.
The Journal of cell biology 2005;169(3):527-38.
2005: Ishikawa Hiroaki; Kubo Akiharu; Tsukita Shoichiro; Tsukita Sachiko
Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia.
Nature cell biology 2005;7(5):517-24.
2005: Ishikawa Hiroaki; Kubo Akiharu; Tsukita Shoichiro; Tsukita Sachiko
Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia.
Nature cell biology 2005;7(5):517-24.
2005: Tamura Atsushi; Kikuchi Shojiro; Hata Masaki; Katsuno Tatsuya; Matsui Takeshi; Hayashi Hisayoshi; Suzuki Yuichi; Noda Tetsuo; Tsukita Shoichiro; Tsukita Sachiko
Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells.
The Journal of cell biology 2005;169(1):21-8.
2005: Tamura Atsushi; Kikuchi Shojiro; Hata Masaki; Katsuno Tatsuya; Matsui Takeshi; Hayashi Hisayoshi; Suzuki Yuichi; Noda Tetsuo; Tsukita Shoichiro; Tsukita Sachiko
Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells.
The Journal of cell biology 2005;169(1):21-8.
2005: Mimori-Kiyosue Yuko; Grigoriev Ilya; Lansbergen Gideon; Sasaki Hiroyuki; Matsui Chiyuki; Severin Fedor; Galjart Niels; Grosveld Frank; Vorobjev Ivan; Tsukita Shoichiro; Akhmanova Anna
CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.
The Journal of cell biology 2005;168(1):141-53.
2004: Kitajiri Shin-ichiro; Miyamoto Tatsuo; Mineharu Akihito; Sonoda Noriyuki; Furuse Kyoko; Hata Masaki; Sasaki Hiroyuki; Mori Yoshiaki; Kubota Takahiro; Ito Juichi; Furuse Mikio; Tsukita Shoichiro
Compartmentalization established by claudin-11-based tight junctions in stria vascularis is required for hearing through generation of endocochlear potential.
Journal of cell science 2004;117(Pt 21):5087-96.
2004: Hashizume Atsushi; Ueno Tomoo; Furuse Mikio; Tsukita Shoichiro; Nakanishi Yasuo; Hieda Yohki
Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(2):425-31.
2004: Hachiya Naomi S; Sakasegawa Yuji; Sasaki Hiroyuki; Jozuka Akiko; Tsukita Shoichiro; Kaneko Kiyotoshi
Oligomeric Aip2p/Dld2p modifies the protein conformation of both properly folded and misfolded substrates in vitro.
Biochemical and biophysical research communications 2004;323(1):339-44.
2004: Ohnishi Hiroe; Nakahara Takuo; Furuse Kyoko; Sasaki Hiroyuki; Tsukita Shoichiro; Furuse Mikio
JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.
The Journal of biological chemistry 2004;279(44):46014-22.
2004: Umeda Kazuaki; Matsui Takeshi; Nakayama Mayumi; Furuse Kyoko; Sasaki Hiroyuki; Furuse Mikio; Tsukita Shoichiro
Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.
The Journal of biological chemistry 2004;279(43):44785-94.
2004: Morita K; Tsukita S; Miyachi Y
Tight junction-associated proteins (occludin, ZO-1, claudin-1, claudin-4) in squamous cell carcinoma and Bowen's disease.
The British journal of dermatology 2004;151(2):328-34.
2004: Kitajiri Shin-ichiro; Fukumoto Kanehisa; Hata Masaki; Sasaki Hiroyuki; Katsuno Tatsuya; Nakagawa Takayuki; Ito Juichi; Tsukita Shoichiro; Tsukita Sachiko
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.
The Journal of cell biology 2004;166(4):559-70.
2004: Kitajiri Shin-ichiro; Fukumoto Kanehisa; Hata Masaki; Sasaki Hiroyuki; Katsuno Tatsuya; Nakagawa Takayuki; Ito Juichi; Tsukita Shoichiro; Tsukita Sachiko
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.
The Journal of cell biology 2004;166(4):559-70.
2004: Hachiya Naomi S; Sakasegawa Yuji; Sasaki Hiroyuki; Jozuka Akiko; Tsukita Shoichiro; Kaneko Kiyotoshi
Oligomeric Aip2p/Dld2p forms a novel grapple-like structure and has an ATP-dependent F-actin conformation modifying activity in vitro.
Biochemical and biophysical research communications 2004;320(4):1271-6.
2004: Matsui Takeshi; Hayashi-Kisumi Fumie; Kinoshita Yoko; Katahira Sayaka; Morita Kazumasa; Miyachi Yoshiki; Ono Yuichi; Imai Toshio; Tanigawa Yoko; Komiya Tohru; Tsukita Shoichiro
Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1.
Genomics 2004;84(2):384-97.
2004: Hachiya Naomi S; Sakasegawa Yuji; Jozuka Akiko; Tsukita Shoichiro; Kaneko Kiyotoshi
Interaction of D-lactate dehydrogenase protein 2 (Dld2p) with F-actin: implication for an alternative function of Dld2p.
Biochemical and biophysical research communications 2004;319(1):78-82.
2004: Matsuda Miho; Kubo Akiharu; Furuse Mikio; Tsukita Shoichiro
A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells.
Journal of cell science 2004;117(Pt 7):1247-57.
2004: Kitajiri Shin-iciro; Furuse Mikio; Morita Kazumasa; Saishin-Kiuchi Yumiko; Kido Hirofumi; Ito Juichi; Tsukita Shoichiro
Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.
Hearing research 2004;187(1-2):25-34.
2003: Inoko Akihito; Itoh Masahiko; Tamura Atsushi; Matsuda Miho; Furuse Mikio; Tsukita Shoichiro
Expression and distribution of ZO-3, a tight junction MAGUK protein, in mouse tissues.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(11):837-45.
2003: Hoeflich Klaus P; Tsukita Sachiko; Hicks Leslie; Kay Cyril M; Tsukita Shoichiro; Ikura Mitsuhiko
Insights into a single rod-like helix in activated radixin required for membrane-cytoskeletal cross-linking.
Biochemistry 2003;42(40):11634-41.
2003: Hoeflich Klaus P; Tsukita Sachiko; Hicks Leslie; Kay Cyril M; Tsukita Shoichiro; Ikura Mitsuhiko
Insights into a single rod-like helix in activated radixin required for membrane-cytoskeletal cross-linking.
Biochemistry 2003;42(40):11634-41.
2003: Mimori-Kiyosue Yuko; Tsukita Shoichiro
"Search-and-capture" of microtubules through plus-end-binding proteins (+TIPs).
Journal of biochemistry 2003;134(3):321-6.
2003: Sakasegawa Yuji; Hachiya Naomi S; Tsukita Shoichiro; Kaneko Kiyotoshi
Ecm10p localizes in yeast mitochondrial nucleoids and its overexpression induces extensive mitochondrial DNA aggregations.
Biochemical and biophysical research communications 2003;309(1):217-21.
2003: Tamagawa Hiroshi; Takahashi Ichiro; Furuse Mikio; Yoshitake-Kitano Yuka; Tsukita Shoichiro; Ito Toshinori; Matsuda Hikaru; Kiyono Hiroshi
Characteristics of claudin expression in follicle-associated epithelium of Peyer's patches: preferential localization of claudin-4 at the apex of the dome region.
Laboratory investigation; a journal of technical methods and pathology 2003;83(7):1045-53.
2003: Morita Kazumasa; Sasaki Hiroyuki; Furuse Kyoko; Furuse Mikio; Tsukita Shoichiro; Miyachi Yoshiki
Expression of claudin-5 in dermal vascular endothelia.
Experimental dermatology 2003;12(3):289-95.
2003: Asano Akira; Asano Kimiko; Sasaki Hiroyuki; Furuse Mikio; Tsukita Shoichiro
Claudins in Caenorhabditis elegans: their distribution and barrier function in the epithelium.
Current biology : CB 2003;13(12):1042-6.
2003: Nitta Takehiro; Hata Masaki; Gotoh Shimpei; Seo Yoshiteru; Sasaki Hiroyuki; Hashimoto Nobuo; Furuse Mikio; Tsukita Shoichiro
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice.
The Journal of cell biology 2003;161(3):653-60.
2003: Ikenouchi Junichi; Matsuda Miho; Furuse Mikio; Tsukita Shoichiro
Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail.
Journal of cell science 2003;116(Pt 10):1959-67.
2003: Sasaki Hiroyuki; Matsui Chiyuki; Furuse Kyoko; Mimori-Kiyosue Yuko; Furuse Mikio; Tsukita Shoichiro
Dynamic behavior of paired claudin strands within apposing plasma membranes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3971-6.
2003: Kubo Akiharu; Tsukita Shoichiro
Non-membranous granular organelle consisting of PCM-1: subcellular distribution and cell-cycle-dependent assembly/disassembly.
Journal of cell science 2003;116(Pt 5):919-28.
2003: Hamada Keisuke; Shimizu Toshiyuki; Yonemura Shigenobu; Tsukita Shoichiro; Tsukita Sachiko; Hakoshima Toshio
Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex.
The EMBO journal 2003;22(3):502-14.
2003: Hamada Keisuke; Shimizu Toshiyuki; Yonemura Shigenobu; Tsukita Shoichiro; Tsukita Sachiko; Hakoshima Toshio
Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex.
The EMBO journal 2003;22(3):502-14.
2002: Oda Hiroki; Wada Hiroshi; Tagawa Kunifumi; Akiyama-Oda Yasuko; Satoh Nori; Humphreys Tom; Zhang Shicui; Tsukita Shoichiro
A novel amphioxus cadherin that localizes to epithelial adherens junctions has an unusual domain organization with implications for chordate phylogeny.
Evolution & development 2002;4(6):426-34.
2002: Tsukita Shoichiro; Furuse Mikio
Claudin-based barrier in simple and stratified cellular sheets.
Current opinion in cell biology 2002;14(5):531-6.
2002: Kikuchi Shojiro; Hata Masaki; Fukumoto Kanehisa; Yamane Yukari; Matsui Takeshi; Tamura Atsushi; Yonemura Shigenobu; Yamagishi Hisakazu; Keppler Dietrich; Tsukita Shoichiro; Tsukita Sachiko
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.
Nature genetics 2002;31(3):320-5.
2002: Kikuchi Shojiro; Hata Masaki; Fukumoto Kanehisa; Yamane Yukari; Matsui Takeshi; Tamura Atsushi; Yonemura Shigenobu; Yamagishi Hisakazu; Keppler Dietrich; Tsukita Shoichiro; Tsukita Sachiko
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.
Nature genetics 2002;31(3):320-5.
2002: Morita Kazumasa; Furuse Mikio; Yoshida Yoko; Itoh Masahiko; Sasaki Hiroyuki; Tsukita Shoichiro; Miyachi Yoshiki
Molecular architecture of tight junctions of periderm differs from that of the maculae occludentes of epidermis.
The Journal of investigative dermatology 2002;118(6):1073-9.
2002: Yonemura Shigenobu; Matsui Takeshi; Tsukita Shoichiro; Tsukita Sachiko
Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo.
Journal of cell science 2002;115(Pt 12):2569-80.
2002: Yonemura Shigenobu; Matsui Takeshi; Tsukita Shoichiro; Tsukita Sachiko
Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo.
Journal of cell science 2002;115(Pt 12):2569-80.
2002: Kiuchi-Saishin Yumiko; Gotoh Shimpei; Furuse Mikio; Takasuga Akiko; Tano Yasuo; Tsukita Shoichiro
Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments.
Journal of the American Society of Nephrology : JASN 2002;13(4):875-86.
2002: Furuse Mikio; Hata Masaki; Furuse Kyoko; Yoshida Yoko; Haratake Akinori; Sugitani Yoshinobu; Noda Tetsuo; Kubo Akiharu; Tsukita Shoichiro
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice.
The Journal of cell biology 2002;156(6):1099-111.
2002: Shimizu Toshiyuki; Seto Azusa; Maita Nobuo; Hamada Keisuke; Tsukita Shoichiro; Tsukita Sachiko; Hakoshima Toshio
Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
The Journal of biological chemistry 2002;277(12):10332-6.
2002: Shimizu Toshiyuki; Seto Azusa; Maita Nobuo; Hamada Keisuke; Tsukita Shoichiro; Tsukita Sachiko; Hakoshima Toshio
Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
The Journal of biological chemistry 2002;277(12):10332-6.
2002: Hamazaki Yoko; Itoh Masahiko; Sasaki Hiroyuki; Furuse Mikio; Tsukita Shoichiro
Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule.
The Journal of biological chemistry 2002;277(1):455-61.
2001: Mimori-Kiyosue Y; Tsukita S
Where is APC going?
The Journal of cell biology 2001;154(6):1105-9.
2001: Itoh M; Sasaki H; Furuse M; Ozaki H; Kita T; Tsukita S
Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions.
The Journal of cell biology 2001;154(3):491-7.
2001: Nakagawa Y; Yamane Y; Okanoue T; Tsukita S; Tsukita S
Outer dense fiber 2 is a widespread centrosome scaffold component preferentially associated with mother centrioles: its identification from isolated centrosomes.
Molecular biology of the cell 2001;12(6):1687-97.
2001: Nakagawa Y; Yamane Y; Okanoue T; Tsukita S; Tsukita S
Outer dense fiber 2 is a widespread centrosome scaffold component preferentially associated with mother centrioles: its identification from isolated centrosomes.
Molecular biology of the cell 2001;12(6):1687-97.
2001: Furuse M; Furuse K; Sasaki H; Tsukita S
Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells.
The Journal of cell biology 2001;153(2):263-72.
2001: Tsukita S; Furuse M; Itoh M
Multifunctional strands in tight junctions.
Nature reviews. Molecular cell biology 2001;2(4):285-93.
2001: Hirase T; Kawashima S; Wong E Y; Ueyama T; Rikitake Y; Tsukita S; Yokoyama M; Staddon J M
Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms.
The Journal of biological chemistry 2001;276(13):10423-31.
2000: Saitou M; Furuse M; Sasaki H; Schulzke J D; Fromm M; Takano H; Noda T; Tsukita S
Complex phenotype of mice lacking occludin, a component of tight junction strands.
Molecular biology of the cell 2000;11(12):4131-42.
2000: Takahashi N; Ishihara S; Takada S; Tsukita S; Nagafuchi A
Posttranscriptional regulation of alpha-catenin expression is required for Wnt signaling in L cells.
Biochemical and biophysical research communications 2000;277(3):691-8.
2000: Tachibana K; Nakanishi H; Mandai K; Ozaki K; Ikeda W; Yamamoto Y; Nagafuchi A; Tsukita S; Takai Y
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins.
The Journal of cell biology 2000;150(5):1161-76.
2000: Fujita K; Katahira J; Horiguchi Y; Sonoda N; Furuse M; Tsukita S
Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein.
FEBS letters 2000;476(3):258-61.
2000: Akiyama-Oda Y; Hotta Y; Tsukita S; Oda H
Distinct mechanisms triggering glial differentiation in Drosophila thoracic and abdominal neuroblasts 6-4.
Developmental biology 2000;222(2):429-39.
2000: Tsukita S; Furuse M
Pores in the wall: claudins constitute tight junction strands containing aqueous pores.
The Journal of cell biology 2000;149(1):13-6.
2000: Tsukita S; Furuse M
[Identification of two distinct types of four-transmembrane domain proteins, occludin and claudins: towards new physiology in paracellular pathway]
Seikagaku. The Journal of Japanese Biochemical Society 2000;72(3):155-62.
2000: Tsukita S; Furuse M
The structure and function of claudins, cell adhesion molecules at tight junctions.
Annals of the New York Academy of Sciences 2000;915():129-35.
1999: Itoh M; Furuse M; Morita K; Kubota K; Saitou M; Tsukita S
Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.
The Journal of cell biology 1999;147(6):1351-63.
1999: Tsukita S; Yonemura S
Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins.
The Journal of biological chemistry 1999;274(49):34507-10.
1999: Hiiragi T; Sasaki H; Nagafuchi A; Sabe H; Shen S C; Matsuki M; Yamanishi K; Tsukita S
Transglutaminase type 1 and its cross-linking activity are concentrated at adherens junctions in simple epithelial cells.
The Journal of biological chemistry 1999;274(48):34148-54.
1999: Furuse M; Sasaki H; Tsukita S
Manner of interaction of heterogeneous claudin species within and between tight junction strands.
The Journal of cell biology 1999;147(4):891-903.
1999: Matsui T; Yonemura S; Tsukita S; Tsukita S
Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases.
Current biology : CB 1999;9(21):1259-62.
1999: Matsui T; Yonemura S; Tsukita S; Tsukita S
Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases.
Current biology : CB 1999;9(21):1259-62.
1999: Sonoda N; Furuse M; Sasaki H; Yonemura S; Katahira J; Horiguchi Y; Tsukita S
Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.
The Journal of cell biology 1999;147(1):195-204.
1999: Morita K; Sasaki H; Furuse M; Tsukita S
Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells.
The Journal of cell biology 1999;147(1):185-94.
1999: Tsukita S; Furuse M; Itoh M
Structural and signalling molecules come together at tight junctions.
Current opinion in cell biology 1999;11(5):628-33.
1999: Kubota K; Furuse M; Sasaki H; Sonoda N; Fujita K; Nagafuchi A; Tsukita S
Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions.
Current biology : CB 1999;9(18):1035-8.
1999: Maeda M; Matsui T; Imamura M; Tsukita S; Tsukita S
Expression level, subcellular distribution and rho-GDI binding affinity of merlin in comparison with Ezrin/Radixin/Moesin proteins.
Oncogene 1999;18(34):4788-97.
1999: Maeda M; Matsui T; Imamura M; Tsukita S; Tsukita S
Expression level, subcellular distribution and rho-GDI binding affinity of merlin in comparison with Ezrin/Radixin/Moesin proteins.
Oncogene 1999;18(34):4788-97.
1999: Tsukita S; Furuse M
Occludin and claudins in tight-junction strands: leading or supporting players?
Trends in cell biology 1999;9(7):268-73.
1999: Yonemura S; Tsukita S; Tsukita S
Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins.
The Journal of cell biology 1999;145(7):1497-509.
1999: Yonemura S; Tsukita S; Tsukita S
Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins.
The Journal of cell biology 1999;145(7):1497-509.
1999: Maeno Y; Moroi S; Nagashima H; Noda T; Shiozaki H; Monden M; Tsukita S; Nagafuchi A
alpha-catenin-deficient F9 cells differentiate into signet ring cells.
The American journal of pathology 1999;154(5):1323-8.
1999: Morita K; Sasaki H; Fujimoto K; Furuse M; Tsukita S
Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis.
The Journal of cell biology 1999;145(3):579-88.
1999: Ando-Akatsuka Y; Yonemura S; Itoh M; Furuse M; Tsukita S
Differential behavior of E-cadherin and occludin in their colocalization with ZO-1 during the establishment of epithelial cell polarity.
Journal of cellular physiology 1999;179(2):115-25.
1999: Hayashi K; Yonemura S; Matsui T; Tsukita S
Immunofluorescence detection of ezrin/radixin/moesin (ERM) proteins with their carboxyl-terminal threonine phosphorylated in cultured cells and tissues.
Journal of cell science 1999;112 ( Pt 8)():1149-58.
1999: Imamura Y; Itoh M; Maeno Y; Tsukita S; Nagafuchi A
Functional domains of alpha-catenin required for the strong state of cadherin-based cell adhesion.
The Journal of cell biology 1999;144(6):1311-22.
1999: Itoh M; Morita K; Tsukita S
Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin.
The Journal of biological chemistry 1999;274(9):5981-6.
1999: Gofuku J; Shiozaki H; Tsujinaka T; Inoue M; Tamura S; Doki Y; Matsui S; Tsukita S; Kikkawa N; Monden M
Expression of E-cadherin and alpha-catenin in patients with colorectal carcinoma. Correlation with cancer invasion and metastasis.
American journal of clinical pathology 1999;111(1):29-37.
1999: Morita K; Furuse M; Fujimoto K; Tsukita S
Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):511-6.
1999: Doi Y; Itoh M; Yonemura S; Ishihara S; Takano H; Noda T; Tsukita S
Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.
The Journal of biological chemistry 1999;274(4):2315-21.
1998: Furuse M; Sasaki H; Fujimoto K; Tsukita S
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts.
The Journal of cell biology 1998;143(2):391-401.
1998: Tsukita S; Furuse M
Overcoming barriers in the study of tight junction functions: from occludin to claudin.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(9):569-73.
1998: Furuse M; Fujita K; Hiiragi T; Fujimoto K; Tsukita S
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin.
The Journal of cell biology 1998;141(7):1539-50.
1998: Morita K; Itoh M; Saitou M; Ando-Akatsuka Y; Furuse M; Yoneda K; Imamura S; Fujimoto K; Tsukita S
Subcellular distribution of tight junction-associated proteins (occludin, ZO-1, ZO-2) in rodent skin.
The Journal of investigative dermatology 1998;110(6):862-6.
1998: Moroi S; Saitou M; Fujimoto K; Sakakibara A; Furuse M; Yoshida O; Tsukita S
Occludin is concentrated at tight junctions of mouse/rat but not human/guinea pig Sertoli cells in testes.
The American journal of physiology 1998;274(6 Pt 1):C1708-17.
1998: Saitou M; Fujimoto K; Doi Y; Itoh M; Fujimoto T; Furuse M; Takano H; Noda T; Tsukita S
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions.
The Journal of cell biology 1998;141(2):397-408.
1998: Yonemura S; Hirao M; Doi Y; Takahashi N; Kondo T; Tsukita S; Tsukita S
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.
The Journal of cell biology 1998;140(4):885-95.
1998: Yonemura S; Hirao M; Doi Y; Takahashi N; Kondo T; Tsukita S; Tsukita S
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.
The Journal of cell biology 1998;140(4):885-95.
1998: Matsui T; Maeda M; Doi Y; Yonemura S; Amano M; Kaibuchi K; Tsukita S; Tsukita S
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association.
The Journal of cell biology 1998;140(3):647-57.
1998: Matsui T; Maeda M; Doi Y; Yonemura S; Amano M; Kaibuchi K; Tsukita S; Tsukita S
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association.
The Journal of cell biology 1998;140(3):647-57.
1998: Doi Y; Kurita M; Matsumoto M; Kondo T; Noda T; Tsukita S; Tsukita S; Seya T
Moesin is not a receptor for measles virus entry into mouse embryonic stem cells.
Journal of virology 1998;72(2):1586-92.
1998: Doi Y; Kurita M; Matsumoto M; Kondo T; Noda T; Tsukita S; Tsukita S; Seya T
Moesin is not a receptor for measles virus entry into mouse embryonic stem cells.
Journal of virology 1998;72(2):1586-92.
1997: Kondo T; Takeuchi K; Doi Y; Yonemura S; Nagata S; Tsukita S
ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis.
The Journal of cell biology 1997;139(3):749-58.
1997: Mandai K; Nakanishi H; Satoh A; Obaishi H; Wada M; Nishioka H; Itoh M; Mizoguchi A; Aoki T; Fujimoto T; Matsuda Y; Tsukita S; Takai Y
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction.
The Journal of cell biology 1997;139(2):517-28.
1997: Takahashi K; Sasaki T; Mammoto A; Takaishi K; Kameyama T; Tsukita S; Takai Y
Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein.
The Journal of biological chemistry 1997;272(37):23371-5.
1997: Tsukita S
[Molecular organization and functions of tight junction]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1674-8.
1997: Hirase T; Staddon J M; Saitou M; Ando-Akatsuka Y; Itoh M; Furuse M; Fujimoto K; Tsukita S; Rubin L L
Occludin as a possible determinant of tight junction permeability in endothelial cells.
Journal of cell science 1997;110 ( Pt 14)():1603-13.
1997: Saitou M; Ando-Akatsuka Y; Itoh M; Furuse M; Inazawa J; Fujimoto K; Tsukita S
Mammalian occludin in epithelial cells: its expression and subcellular distribution.
European journal of cell biology 1997;73(3):222-31.
1997: Itoh M; Nagafuchi A; Moroi S; Tsukita S
Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments.
The Journal of cell biology 1997;138(1):181-92.
1997: Kimura Y; Shiozaki H; Hirao M; Maeno Y; Doki Y; Inoue M; Monden T; Ando-Akatsuka Y; Furuse M; Tsukita S; Monden M
Expression of occludin, tight-junction-associated protein, in human digestive tract.
The American journal of pathology 1997;151(1):45-54.
1997: Sakakibara A; Furuse M; Saitou M; Ando-Akatsuka Y; Tsukita S
Possible involvement of phosphorylation of occludin in tight junction formation.
The Journal of cell biology 1997;137(6):1393-401.
1997: Hirase T; Furuse M; Tsukita S
A 155-kDa undercoat-constitutive protein of cell-to-cell adherens junctions.
European journal of cell biology 1997;72(2):174-81.
1997: Fujimoto K; Nagafuchi A; Tsukita S; Kuraoka A; Ohokuma A; Shibata Y
Dynamics of connexins, E-cadherin and alpha-catenin on cell membranes during gap junction formation.
Journal of cell science 1997;110 ( Pt 3)():311-22.
1997: Tsukita S; Yonemura S
ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction.
Current opinion in cell biology 1997;9(1):70-5.
1997: Tsukita S; Furuse M; Itoh M
Molecular architecture of tight junctions: occludin and ZO-1.
Society of General Physiologists series 1997;52():69-76.

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