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Akito Tsutsumi

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Koki Hikami; Aya Kawasaki; Ikue Ito; Minori Koga; Satoshi Ito; Taichi Hayashi; Isao Matsumoto; Akito Tsutsumi; Makio Kusaoi; Yoshinari Takasaki; Hiroshi Hashimoto; Tadao Arinami; Takayuki Sumida; Naoyuki Tsuchiya
Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus.
Hiroshi Ogishima; Satoshi Ito; Akito Tsutsumi; Makoto Sugihara; Daisuke Goto; Isao Matsumoto; Mana Obata Yasuoka; Hiromi Hamada; Hiroyuki Yoshikawa; Hideto Takahashi; Atsuko Murashima; Takayuki Sumida
High-dose unfractionated heparin therapy in a pregnant patient with antiphospolipid syndrome: a case report.
Yinan Wang; Satoshi Ito; Yusuke Chino; Daisuke Goto; Isao Matsumoto; Hideyuki Murata; Akito Tsutsumi; Taichi Hayashi; K Uchida; Joichi Usui; K Yamagata; Takayuki Sumida
Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis.

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All Publications

2011: Koki Hikami; Aya Kawasaki; Ikue Ito; Minori Koga; Satoshi Ito; Taichi Hayashi; Isao Matsumoto; Akito Tsutsumi; Makio Kusaoi; Yoshinari Takasaki; Hiroshi Hashimoto; Tadao Arinami; Takayuki Sumida; Naoyuki Tsuchiya
Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus.
Arthritis and rheumatism 2011;63(3):755-63.
2010: Hiroshi Ogishima; Satoshi Ito; Akito Tsutsumi; Makoto Sugihara; Daisuke Goto; Isao Matsumoto; Mana Obata Yasuoka; Hiromi Hamada; Hiroyuki Yoshikawa; Hideto Takahashi; Atsuko Murashima; Takayuki Sumida
High-dose unfractionated heparin therapy in a pregnant patient with antiphospolipid syndrome: a case report.
International journal of rheumatic diseases 2010;13(3):e32-5.
2010: Yinan Wang; Satoshi Ito; Yusuke Chino; Daisuke Goto; Isao Matsumoto; Hideyuki Murata; Akito Tsutsumi; Taichi Hayashi; K Uchida; Joichi Usui; K Yamagata; Takayuki Sumida
Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis.
Clinical and experimental immunology 2010;159(1):1-10.
2009: Akito Tsutsumi; Tetsuo Kobayashi; Satoshi Ito; Daisuke Goto; Isao Matsumoto; Hiromasa Yoshie; Takayuki Sumida
Mannose binding lectin gene polymorphism and the severity of chronic periodontitis.
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2009;32(1):48-52.
2009: Ikue Ito; Aya Kawasaki; Satoshi Ito; Taichi Hayashi; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Geoffrey Hom; Robert R Graham; Yoshinari Takasaki; Hiroshi Hashimoto; Jun Ohashi; timothy wayne behrens; Takayuki Sumida; Naoyuki Tsuchiya
Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population.
Arthritis and rheumatism 2009;60(2):553-8.
2009: Y Tanaka-Watanabe; Isao Matsumoto; K Iwanami; A Inoue; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
B cells play a crucial role as antigen-presenting cells and collaborate with inflammatory cytokines in glucose-6-phosphate isomerase-induced arthritis.
Clinical and experimental immunology 2009;155(2):285-94.
2008: Y Yoshiga; Daisuke Goto; S Segawa; Y Ohnishi; Isao Matsumoto; Satoshi Ito; Akito Tsutsumi; M Taniguchi; Takayuki Sumida
Invariant NKT cells produce IL-17 through IL-23-dependent and -independent pathways with potential modulation of Th17 response in collagen-induced arthritis.
International journal of molecular medicine 2008;22(3):369-74.
2008: Wataru Ishii; Satoshi Ito; Yuya Kondo; Hiroto Tsuboi; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Takayuki Sumida; Yasushi Okoshi; Yuichi Hasegawa; Hiroshi Kojima; Shingo Sakashita; K Aita; Masayuki Noguchi
Intravascular large B-cell lymphoma with acute abdomen as a presenting symptom in a patient with systemic lupus erythematosus.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(9):1553-5.
2008: Keiichi Iwanami; Isao Matsumoto; Yoko Tanaka-Watanabe; Asuka Inoue; Masahiko Mihara; Yoshiyuki Ohsugi; Mizuko Mamura; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Tadamitsu Kishimoto; Takayuki Sumida
Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase.
Arthritis and rheumatism 2008;58(3):754-63.
2008: Keiichi Iwanami; Isao Matsumoto; Yoko Tanaka; Asuka Inoue; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis.
Arthritis research & therapy 2008;10(6):R130.
2008: Aya Kawasaki; Ikue Ito; Koki Hikami; Jun Ohashi; Taichi Hayashi; Daisuke Goto; Isao Matsumoto; Satoshi Ito; Akito Tsutsumi; Minori Koga; Tadao Arinami; Robert R Graham; Geoffrey Hom; Yoshinari Takasaki; Hiroshi Hashimoto; timothy wayne behrens; Takayuki Sumida; Naoyuki Tsuchiya
Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.
Arthritis research & therapy 2008;10(5):R113.
2008: Takeshi Suzuki; Akito Tsutsumi; Hiroyuki Suzuki; Eiji Suzuki; Makoto Sugihara; Yoshifumi Muraki; Taichi Hayashi; Yusuke Chino; Daisuke Goto; Isao Matsumoto; Satoshi Ito; Keiji Miyazawa; Takayuki Sumida
Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals.
Modern rheumatology / the Japan Rheumatism Association 2008;18(5):472-9.
2008: Isao Matsumoto; Hua Zhang; Takanori Yasukochi; Keiichi Iwanami; Yoko Tanaka; Asuka Inoue; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Therapeutic effects of antibodies to tumor necrosis factor-alpha, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis.
Arthritis research & therapy 2008;10(3):R66.
2008: Mika Kohno; Akito Tsutsumi; Hiroto Matsui; Makoto Sugihara; Takeshi Suzuki; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Satoshi Ito; Toru Suguro; Takayuki Sumida
Interleukin-17 gene expression in patients with rheumatoid arthritis.
Modern rheumatology / the Japan Rheumatism Association 2008;18(1):15-22.
2008: Y Nakamura; Ei Wakamatsu; Isao Matsumoto; M Tomiita; Y Kohno; M Mori; S Yokota; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
High prevalence of autoantibodies to muscarinic-3 acetylcholine receptor in patients with juvenile-onset Sjögren syndrome.
Annals of the rheumatic diseases 2008;67(1):136-7.
2007: Taichi Hayashi; Isao Matsumoto; Takanori Yasukochi; Mizuko Mamura; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Biased usage of synovial immunoglobulin heavy chain variable region 4 by the anti-glucose-6-phosphate isomerase antibody in patients with rheumatoid arthritis.
International journal of molecular medicine 2007;20(2):247-53.
2007: Makoto Sugihara; Akito Tsutsumi; Eiji Suzuki; Ei Wakamatsu; Takeshi Suzuki; Hiroshi Ogishima; Taichi Hayashi; Yusuke Chino; Wataru Ishii; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Satoshi Ito; Takayuki Sumida
Effects of infliximab therapy on gene expression levels of tumor necrosis factor alpha, tristetraprolin, T cell intracellular antigen 1, and Hu antigen R in patients with rheumatoid arthritis.
Arthritis and rheumatism 2007;56(7):2160-9.
2007: Ei Wakamatsu; Yumi Nakamura; Isao Matsumoto; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
DNA microarray analysis of labial salivary glands of patients with Sjogren's syndrome.
Annals of the rheumatic diseases 2007;66(6):844-5.
2007: Terukazu Enami; Takeshi Suzuki; Satoshi Ito; Ai Yoshimi; Makoto Sugihara; Mizuko Mamura; Taichi Hayashi; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Takayuki Sumida
Successful treatment of refractory thrombotic thrombocytopenic purpura with cyclosporine and corticosteroids in a patient with systemic lupus erythematosus and antibodies to ADAMTS13.
Internal medicine (Tokyo, Japan) 2007;46(13):1033-7.
2007: Hideyasu Yamada; Wataru Ishii; Satoshi Ito; Keiichi Iwanami; Hiroshi Ogishima; Takeshi Suzuki; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Takayuki Sumida
Sarcoid myositis with muscle weakness as a presenting symptom.
Modern rheumatology / the Japan Rheumatism Association 2007;17(3):243-6.
2007: Masashi Matsuyama; Takeshi Suzuki; Hiroto Tsuboi; Satoshi Ito; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Takayuki Sumida
Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman's disease.
Internal medicine (Tokyo, Japan) 2007;46(11):771-4.
2006: Ei Wakamatsu; Isao Matsumoto; Takanori Yasukochi; Yusuke Naito; Daisuke Goto; Mizuko Mamura; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Overexpression of phosphorylated STAT-1alpha in the labial salivary glands of patients with Sjögren's syndrome.
Arthritis and rheumatism 2006;54(11):3476-84.
2006: Eiji Suzuki; Akito Tsutsumi; Makoto Sugihara; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Satoshi Ito; Kotaro Ikeda; Naoyuki Ochiai; Yukio Sato; Takayuki Sumida
Expression of TNF-alpha, tristetraprolin, T-cell intracellular antigen-1 and Hu antigen R genes in synovium of patients with rheumatoid arthritis.
International journal of molecular medicine 2006;18(2):273-8.
2006: Yuko Kori; Isao Matsumoto; Hua Zhang; Takanori Yasukochi; Taichi Hayashi; K Iwanami; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Characterisation of Th1/Th2 type, glucose-6-phosphate isomerase reactive T cells in the generation of rheumatoid arthritis.
Annals of the rheumatic diseases 2006;65(7):968-9.
2006: Atsushi Uchida; Makoto Sugihara; Satoshi Ito; Takeshi Nowatari; Toshio Kunikata; Takeshi Suzuki; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Takayuki Sumida
[Ovarian cancer with swelling of the right upper arm, amyopathic dermatomyositis, and elevated serum KL-6].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2006;95(4):742-4.
2006: Yusuke Naito; Isao Matsumoto; Ei Wakamatsu; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Altered peptide ligands regulate muscarinic acetylcholine receptor reactive T cells of patients with Sjögren's syndrome.
Annals of the rheumatic diseases 2006;65(2):269-71.
2006: Yasuyuki Ohnishi; Akito Tsutsumi; Isao Matsumoto; Daisuke Goto; Satoshi Ito; Masataka Kuwana; Yasushi Uemura; Yasuharu Nishimura; Takayuki Sumida
Altered peptide ligands control type II collagen-reactive T cells from rheumatoid arthritis patients.
Modern rheumatology / the Japan Rheumatism Association 2006;16(4):226-8.
2006: Akito Tsutsumi; Taichi Hayashi; Yusuke Chino; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Satoshi Ito; Takayuki Sumida
Significance of antiprothrombin antibodies in patients with systemic lupus erythematosus: clinical evaluation of the antiprothrombin assay and the antiphosphatidylserine/prothrombin assay, and comparison with other antiphospholipid antibody assays.
Modern rheumatology / the Japan Rheumatism Association 2006;16(3):158-64.
2006: Satoshi Ito; Makoto Sugihara; Takeshi Suzuki; Mizuko Mamura; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Takayuki Sumida
Diagnosis of chlamydia-induced reactive arthritis.
Internal medicine (Tokyo, Japan) 2006;45(1):37.
2006: Yusuke Chino; Hideyuki Murata; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Tohru Sakamoto; Morio Ohtsuka; Kiyohisa Sekisawa; Satoshi Ito; Takayuki Sumida
T cell receptor BV gene repertoire of lymphocytes in bronchoalveolar lavage fluid of polymyositis/dermatomyositis patients with interstitial pneumonitis.
International journal of molecular medicine 2006;17(1):101-9.
2005: Shoko Miyahara; Satoshi Ito; Atsuko Soeda; Yusuke Chino; Taichi Hayashi; Reiko Takahashi; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Takayuki Sumida
Two cases of systemic lupus erythematosus complicated with colonic ulcers.
Internal medicine (Tokyo, Japan) 2005;44(12):1298-306.
2005: Isao Matsumoto; Yoshifumi Muraki; Takanori Yasukochi; Zhang Hua; Yuko Kori; Taichi Hayashi; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Kotaro Ikeda; Hiroshi Sumichika; Takayuki Sumida
The exploration of joint-specific immunoreactions on immunoglobulins G of anti-glucose-6-phosphate isomerase antibody-positive patients with rheumatoid arthritis.
International journal of molecular medicine 2005;16(5):793-800.
2005: Takeshi Suzuki; Yoshifumi Muraki; Takanori Yasukochi; Hua Zhang; Yuko Kori; Ei Wakamatsu; Taichi Hayashi; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Hiroshi Sumichika; Takayuki Sumida; Isao Matsumoto
Immunoglobulin G from anti-glucose-6-phosphate isomerase antibodies positive patient with rheumatoid arthritis induces synovitis in cynomolgus monkeys.
Autoimmunity reviews 2005;4(7):475-8.
2005: Y Ohnishi; Akito Tsutsumi; Daisuke Goto; S Itoh; Isao Matsumoto; M Taniguchi; Takayuki Sumida
TCR Valpha14 natural killer T cells function as effector T cells in mice with collagen-induced arthritis.
Clinical and experimental immunology 2005;141(1):47-53.
2005: Akito Tsutsumi
[Palindromic rheumatism].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 5():285-8.
2005: Yusuke Naito; Isao Matsumoto; Ei Wakamatsu; Daisuke Goto; T Sugiyama; R Matsumura; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Muscarinic acetylcholine receptor autoantibodies in patients with Sjögren's syndrome.
Annals of the rheumatic diseases 2005;64(3):510-1.
2005: Takashi Tomoo; Akito Tsutsumi; Takanori Yasukochi; Kotaro Ikeda; Naoyuki Ochiai; Kazuo Ozawa; Yasuhiko Shibanaka; Satoshi Ito; Isao Matsumoto; Daisuke Goto; Takayuki Sumida
Analysis of abnormally expressed genes in synovium from patients with rheumatoid arthritis using a column gel electrophoresis-coupled subtractive hybridization technique.
International journal of molecular medicine 2005;15(3):453-7.
2005: Reiko Takahashi; Akito Tsutsumi; K Ohtani; Y Muraki; Daisuke Goto; Isao Matsumoto; N Wakamiya; Takayuki Sumida
Association of mannose binding lectin (MBL) gene polymorphism and serum MBL concentration with characteristics and progression of systemic lupus erythematosus.
Annals of the rheumatic diseases 2005;64(2):311-4.
2005: Minetake Kitagawa; Daisuke Goto; Mizuko Mamura; Isao Matsumoto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Identification of three novel peptides that inhibit CD40-CD154 interaction.
Modern rheumatology / the Japan Rheumatism Association 2005;15(6):423-6.
2005: Taichi Hayashi; Isao Matsumoto; Yoshifumi Muraki; Reiko Takahashi; Yusuke Chino; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis.
Modern rheumatology / the Japan Rheumatism Association 2005;15(4):258-63.
2005: Isao Matsumoto; Hua Zhang; Yoshifumi Muraki; Taichi Hayashi; Takanori Yasukochi; Yuko Kori; Daisuke Goto; Satoshi Ito; Akito Tsutsumi; Takayuki Sumida
A functional variant of Fcgamma receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies.
Arthritis research & therapy 2005;7(6):R1183-8.
2004: Yoshifumi Muraki; Isao Matsumoto; Yusuke Chino; Taichi Hayashi; Eiji Suzuki; Daisuke Goto; Satoshi Ito; Hideyuki Murata; Akito Tsutsumi; Takayuki Sumida
Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies: possible mechanism of autoantibody production.
Biochemical and biophysical research communications 2004;323(2):518-22.
2004: Akito Tsutsumi; Eiji Suzuki; Yoshihiro Adachi; Hideyuki Murata; Daisuke Goto; Satoshi Kojo; Isao Matsumoto; Lei Zhong; Hiroshi Nakamura; Takayuki Sumida
Expression of tristetraprolin (G0S24) mRNA, a regulator of tumor necrosis factor-alpha production, in synovial tissues of patients with rheumatoid arthritis.
The Journal of rheumatology 2004;31(6):1044-9.
2004: Reiko Takahashi; Akito Tsutsumi; K Ohtani; Daisuke Goto; Isao Matsumoto; S Ito; N Wakamiya; Takayuki Sumida
Anti-mannose binding lectin antibodies in sera of Japanese patients with systemic lupus erythematosus.
Clinical and experimental immunology 2004;136(3):585-90.
2004: Yoshifumi Muraki; Akito Tsutsumi; Reiko Takahashi; Eiji Suzuki; Taichi Hayashi; Yusuke Chino; Daisuke Goto; Isao Matsumoto; Hideyuki Murata; Emiko Noguchi; Takayuki Sumida
Polymorphisms of IL-1 beta gene in Japanese patients with Sjögren's syndrome and systemic lupus erythematosus.
The Journal of rheumatology 2004;31(4):720-5.
2004: Hideyuki Murata; Yoshihiro Adachi; Takehiko Ebitsuka; Yusuke Chino; Reiko Takahashi; Taichi Hayashi; Daisuke Goto; Isao Matsumoto; Akito Tsutsumi; Hideyuki Akaza; Takayuki Sumida
Reiter's syndrome following intravesical bacille biliE de Calmette-GuErin treatment for superficial bladder carcinoma: report of six cases.
Modern rheumatology / the Japan Rheumatism Association 2004;14(1):82-6.
2003: Satoshi Kojo; Akito Tsutsumi; Daisuke Goto; Takayuki Sumida
Low expression levels of soluble CD1d gene in patients with rheumatoid arthritis.
The Journal of rheumatology 2003;30(12):2524-8.
2003: Akito Tsutsumi; Hiroshi Ikegami; Reiko Takahashi; Hideyuki Murata; Daisuke Goto; Isao Matsumoto; Tomomi Fujisawa; Takayuki Sumida
Mannose binding lectin gene polymorphism in patients with type I diabetes.
Human immunology 2003;64(6):621-4.
2003: Yasuyuki Ohnishi; Akito Tsutsumi; Tateo Sakamaki; Takayuki Sumida
T cell epitopes of type II collagen in HLA-DRB1*0101 or DRB1*0405-positive Japanese patients with rheumatoid arthritis.
International journal of molecular medicine 2003;11(3):331-5.
2002: Takanori Yasukochi; Kazuo Ozawa; Masaaki Sato; Akito Tsutsumi; Takayuki Sumida; Yasuhiko Shibanaka
Evaluation of the improvement of IGCR technique.
Nucleic acids research. Supplement (2001) 2002;(2):199-200.
2001: Akito Tsutsumi; K Sasaki; N Wakamiya; Kunio Ichikawa; T Atsumi; K Ohtani; Y Suzuki; T Koike; Takayuki Sumida
Mannose-binding lectin gene: polymorphisms in Japanese patients with systemic lupus erythematosus, rheumatoid arthritis and Sjögren's syndrome.
Genes and immunity 2001;2(2):99-104.
2000: S Kojo; Y Adachi; Akito Tsutsumi; Takayuki Sumida
Alternative splicing forms of the human CD1D gene in mononuclear cells.
Biochemical and biophysical research communications 2000;276(1):107-11.