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Masahiro Tsutsumi

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Atsushi Shibata; Daisuke Maeda; Hideki Ogino; Masahiro Tsutsumi; Takehiko Nohmi; Hitoshi Nakagama; Takashi Sugimura; Hirobumi Teraoka; Mitsuko Masutani
Role of Parp-1 in suppressing spontaneous deletion mutation in the liver and brain of mice at adolescence and advanced age.
Ayumi Denda; Wakashi Kitayama; Hideki Kishida; Nao Murata; Kazutoshi Tamura; Osamu Kusuoka; Masahiro Tsutsumi; Fumiko Nishikawa; Eiji Kita; Dai Nakae; Yoichi Konishi; Hiroki Kuniyasu
Expression of inducible nitric oxide (NO) synthase but not prevention by its gene ablation of hepatocarcinogenesis with fibrosis caused by a choline-deficient, L-amino acid-defined diet in rats and mice.
Akemi Gunji; Akiko Uemura; Masahiro Tsutsumi; Tadashige Nozaki; Osamu Kusuoka; Ken Omura; Hiroshi Suzuki; Hitoshi Nakagama; Takashi Sugimura; Mitsuko Masutani
Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts.

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All Publications

2009: Atsushi Shibata; Daisuke Maeda; Hideki Ogino; Masahiro Tsutsumi; Takehiko Nohmi; Hitoshi Nakagama; Takashi Sugimura; Hirobumi Teraoka; Mitsuko Masutani
Role of Parp-1 in suppressing spontaneous deletion mutation in the liver and brain of mice at adolescence and advanced age.
Mutation research 2009;664(1-2):20-7.
2007: Ayumi Denda; Wakashi Kitayama; Hideki Kishida; Nao Murata; Kazutoshi Tamura; Osamu Kusuoka; Masahiro Tsutsumi; Fumiko Nishikawa; Eiji Kita; Dai Nakae; Yoichi Konishi; Hiroki Kuniyasu
Expression of inducible nitric oxide (NO) synthase but not prevention by its gene ablation of hepatocarcinogenesis with fibrosis caused by a choline-deficient, L-amino acid-defined diet in rats and mice.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2007;16(1):164-76.
2006: Akemi Gunji; Akiko Uemura; Masahiro Tsutsumi; Tadashige Nozaki; Osamu Kusuoka; Ken Omura; Hiroshi Suzuki; Hitoshi Nakagama; Takashi Sugimura; Mitsuko Masutani
Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts.
Cancer letters 2006;241(1):87-92.
2004: Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Hiroki Kuniyasu; Masahiro Tsutsumi
Alterations of the Dutt1/Robo1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Molecular carcinogenesis 2004;40(4):241-6.
2004: Kanya Honoki; Kazuhiro Yoshitani; Toshifumi Tsujiuchi; Toshio Mori; Masahiro Tsutsumi; Toru Morishita; Yoshinori Takakura; Yoshio Mii
Growth inhibition and induction of apoptosis by flavopiridol in rat lung adenocarcinoma, osteosarcoma and malignant fibrous histiocytoma cell lines.
Oncology reports 2004;11(5):1025-30.
2004: Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Hiroki Kuniyasu; Yoichi Konishi; Masahiro Tsutsumi
Alterations of the M6p/Igf2 receptor gene in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats.
Molecular carcinogenesis 2004;39(4):199-205.
2004: Kanya Honoki; Toshifumi Tsujiuchi; Toshio Mori; Kazuhiro Yoshitani; Masahiro Tsutsumi; Yoshinori Takakura; Yoshio Mii
Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines.
Molecular carcinogenesis 2004;39(1):10-4.
2003: Tadashige Nozaki; Hisako Fujihara; Masatoshi Watanabe; Masahiro Tsutsumi; Kentaro Nakamoto; Osamu Kusuoka; Nobuo Kamada; Hiroshi Suzuki; Hitoshi Nakagama; Takashi Sugimura; Mitsuko Masutani
Parp-1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane.
Cancer science 2003;94(6):497-500.
2003: Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Yoichi Konishi; Masahiro Tsutsumi
Fhit gene alterations in hepatocarcinogenesis induced by a choline-deficient L-amino acid-defined diet in rats.
Molecular carcinogenesis 2003;36(3):147-52.
2003: Toshifumi Tsujiuchi; Yasutaka Sasaki; Tadahiko Kubozoe; Yoichi Konishi; Masahiro Tsutsumi
Alterations in the Fhit gene in pancreatic duct adenocarcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Molecular carcinogenesis 2003;36(2):60-6.
2003: Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi
Alterations of the M6p/Igf2 receptor gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Molecular carcinogenesis 2003;36(1):32-7.
2002: Toshifumi Tsujiuchi; Yasutaka Sasaki; Yoichi Konishi; Masahiro Tsutsumi
Alterations of the retinoblastoma-related gene RB2/p130 in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Molecular carcinogenesis 2002;35(2):57-62.
2002: Toshifumi Tsujiuchi; Yasutaka Sasaki; Tadahiko Kubozoe; Masahiro Tsutsumi; Yoichi Konishi; Dai Nakae
Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats.
Molecular carcinogenesis 2002;34(1):19-24.
2002: Ayumi Denda; Wakashi Kitayama; Akiko Murata; Hideki Kishida; Yasutaka Sasaki; Osamu Kusuoka; Toshifumi Tsujiuchi; Masahiro Tsutsumi; Dai Nakae; Hidetoshi Takagi; Yoichi Konishi
Increased expression of cyclooxygenase-2 protein during rat hepatocarcinogenesis caused by a choline-deficient, L-amino acid-defined diet and chemopreventive efficacy of a specific inhibitor, nimesulide.
Carcinogenesis 2002;23(2):245-56.
2002: Ayumi Denda; Wakashi Kitayama; Hideki Kishida; Nao Murata; Masahiro Tsutsumi; Toshifumi Tsujiuchi; Dai Nakae; Yoichi Konishi
Development of hepatocellular adenomas and carcinomas associated with fibrosis in C57BL/6J male mice given a choline-deficient, L-amino acid-defined diet.
Japanese journal of cancer research : Gann 2002;93(2):125-32.
2002: Kanya Honoki; Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Toru Morishita; Akira Kido; Yoshizumi Miyauchi; Yoshio Mii; Yoshinori Takakura; Yoichi Konishi
Differential expression of cytokines in rat osteosarcoma and malignant fibrous histiocytoma cell lines induced by 4-(hydroxyamino)quinoline-1-oxide.
Molecular carcinogenesis 2002;33(2):81-7.
2001: Hiroki Kuniyasu; Naohide Oue; Masahiro Tsutsumi; E Tahara; Wataru Yasui
Heparan sulfate enhances invasion by human colon carcinoma cell lines through expression of CD44 variant exon 3.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(12):4067-72.
2001: Toshifumi Tsujiuchi; Yasutaka Sasaki; Nao Murata; Masahiro Tsutsumi; Yoichi Konishi; Dai Nakae
FHIT alterations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Carcinogenesis 2001;22(12):2017-22.
2001: Toshifumi Tsujiuchi; Yasutaka Sasaki; Nao Murata; Masahiro Tsutsumi; Dai Nakae; Yoichi Konishi
Elevated expression of transforming growth factor betas and the tumor necrosis factor family in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2001;53(4):291-5.
2001: Tadahiko Kubozoe; Toshifumi Tsujiuchi; Nao Murata; Yasutaka Sasaki; Tsukasa Tsunoda; Yoichi Konishi; Masahiro Tsutsumi
Absence of beta-catenin gene mutations in pancreatic duct lesions induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Cancer letters 2001;168(1):1-6.
2001: Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi
Absence of PTEN/MMAC1 gene mutations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Cancer letters 2001;162(2):207-11.
2001: Yasutaka Sasaki; Toshifumi Tsujiuchi; Nao Murata; Masahiro Tsutsumi; Yoichi Konishi
Alterations of the transforming growth factor-beta signaling pathway in hepatocellular carcinomas induced endogenously and exogenously in rats.
Japanese journal of cancer research : Gann 2001;92(1):16-22.
2001: Masahiro Tsutsumi; Mitsuko Masutani; Tadashige Nozaki; Osamu Kusuoka; Toshifumi Tsujiuchi; Hitoshi Nakagama; Hiroshi Suzuki; Yoichi Konishi; Takashi Sugimura
Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout mice to nitrosamine carcinogenicity.
Carcinogenesis 2001;22(1):1-3.
2000: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Yasutaka Sasaki; Nao Murata; Yoichi Konishi
Mutations of adenomatous polyposis coli and beta-catenin genes during progression of lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Cancer research 2000;60(23):6611-6.
2000: Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi
Mutations and reduced expression of the transforming growth factor-beta receptor II gene in rat lung adenocarcinomas induced by N-nitrosobis-(2-hydroxypropyl)amine.
Japanese journal of cancer research : Gann 2000;91(11):1090-5.
2000: Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi
Mutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Molecular carcinogenesis 2000;29(2):87-91.
2000: Masahiro Tsutsumi; K Kadomatsu; Toshifumi Tsujiuchi; H Sakitani; S Ikematsu; Tadahiko Kubozoe; M Yoshimoto; T Muramatsu; S Sakuma; Yoichi Konishi
Overexpression of midkine in pancreatic duct adenocarcinomas induced by N-Nitrosobis(2-oxopropyl)amine in hamsters and their cell lines.
Japanese journal of cancer research : Gann 2000;91(10):979-86.
2000: Toshifumi Tsujiuchi; Yasutaka Sasaki; Masahiro Tsutsumi; Yoichi Konishi
Elevated expression of interleukins in lung adenocarcinomas induced by N-Nitrosobis(2-hydroxypropyl)amine in rats.
Japanese journal of cancer research : Gann 2000;91(10):955-9.
2000: Kanya Honoki; Toshifumi Tsujiuchi; Masahiro Tsutsumi; Akira Kido; Toru Morishita; M Yoshimoto; Yoshizumi Miyauchi; Yoshio Mii; S Tamai; Yoichi Konishi
Possible involvement of bcl-2 suppression in wild-type p53 gene-dependent cell growth repression in rat osteosarcoma cells.
Toxicologic pathology 2000;28(4):575-9.
2000: Yasutaka Sasaki; Toshifumi Tsujiuchi; Nao Murata; Tadahiko Kubozoe; Masahiro Tsutsumi; Yoichi Konishi
Absence of p16, p21 and p53 gene alterations in hepatocellular carcinomas induced by N-nitrosodiethylamine or a choline-deficient L-amino acid-defined diet in rats.
Cancer letters 2000;152(1):71-7.
2000: Mitsuko Masutani; Tadashige Nozaki; K Nakamoto; Hitoshi Nakagama; Hiroshi Suzuki; Osamu Kusuoka; Masahiro Tsutsumi; Takashi Sugimura
The response of Parp knockout mice against DNA damaging agents.
Mutation research 2000;462(2-3):159-66.
2000: Dai Nakae; H Akai; Hideki Kishida; Osamu Kusuoka; Masahiro Tsutsumi; Yoichi Konishi
Age and organ dependent spontaneous generation of nuclear 8-hydroxydeoxyguanosine in male Fischer 344 rats.
Laboratory investigation; a journal of technical methods and pathology 2000;80(2):249-61.
2000: Wakashi Kitayama; Ayumi Denda; J Yoshida; Yasutaka Sasaki; M Takahama; K Murakawa; Toshifumi Tsujiuchi; Masahiro Tsutsumi; Yoichi Konishi
Increased expression of cyclooxygenase-2 protein in rat lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine.
Cancer letters 2000;148(2):145-52.
2000: Masahiro Tsutsumi; H Kitada; K Shiraiwa; M Takahama; Toshifumi Tsujiuchi; H Sakitani; Yasutaka Sasaki; K Murakawa; M Yoshimoto; Yoichi Konishi
Inhibitory effects of combined administration of antibiotics and anti-inflammatory drugs on lung tumor development initiated by N-nitrosobis(2-hydroxypropyl)amine in rats.
Carcinogenesis 2000;21(2):251-6.
2000: Masahiro Tsutsumi; Yoichi Konishi
Precancerous conditions for pancreatic cancer.
Journal of hepato-biliary-pancreatic surgery 2000;7(6):575-9.
1999: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Yasutaka Sasaki; M Takahama; Yoichi Konishi
Hypomethylation of CpG sites and c-myc gene overexpression in hepatocellular carcinomas, but not hyperplastic nodules, induced by a choline-deficient L-amino acid-defined diet in rats.
Japanese journal of cancer research : Gann 1999;90(9):909-13.
1999: M Yoshimoto; Masahiro Tsutsumi; K Iki; Yasutaka Sasaki; Toshifumi Tsujiuchi; Takashi Sugimura; K Wakabayashi; Yoichi Konishi
Carcinogenicity of heterocyclic amines for the pancreatic duct epithelium in hamsters.
Cancer letters 1999;143(2):235-9.
1999: M Takahama; Masahiro Tsutsumi; Toshifumi Tsujiuchi; K Nezu; Keiji Kushibe; S Taniguchi; Y Kotake; Y Konishi
Enhanced expression of Tie2, its ligand angiopoietin-1, vascular endothelial growth factor, and CD31 in human non-small cell lung carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2506-10.
1999: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Yasutaka Sasaki; M Takahama; Yoichi Konishi
Different frequencies and patterns of beta-catenin mutations in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats.
Cancer research 1999;59(16):3904-7.
1999: K Iki; Masahiro Tsutsumi; Akira Kido; H Sakitani; M Takahama; M Yoshimoto; M Motoyama; K Tatsumi; Tsukasa Tsunoda; Yoichi Konishi
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis 1999;20(7):1323-9.
1999: Akira Kido; Masahiro Tsutsumi; K Iki; M Takahama; Toshifumi Tsujiuchi; Toru Morishita; S Tamai; Yoichi Konishi
Overexpression of matrix metalloproteinase (MMP)-9 correlates with metastatic potency of spontaneous and 4-hydroxyaminoquinoline 1-oxide (4-HAQO)-induced transplantable osteosarcomas in rats.
Cancer letters 1999;137(2):209-16.
1999: M Takahama; Masahiro Tsutsumi; Toshifumi Tsujiuchi; Akira Kido; H Sakitani; K Iki; S Taniguchi; S Kitamura; Yoichi Konishi
Expression of vascular endothelial growth factor and its receptors during lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine in rats.
Molecular carcinogenesis 1999;24(4):287-93.
1999: Akira Kido; Masahiro Tsutsumi; K Iki; M Motoyama; M Takahama; Toshifumi Tsujiuchi; Toru Morishita; K Tatsumi; S Tamai; Yoichi Konishi
Inhibition of spontaneous rat osteosarcoma lung metastasis by 3S-[4-(N-hydroxyamino)-2R-isobutylsuccinyl]amino-1-methoxy-3,4-dihydroc arbostyril, a novel matrix metalloproteinase inhibitor.
Japanese journal of cancer research : Gann 1999;90(3):333-41.
1999: H Sakitani; Masahiro Tsutsumi; K Kadomatsu; S Ikematsu; M Takahama; K Iki; Toshifumi Tsujiuchi; T Muramatsu; S Sakuma; T Sakaki; Yoichi Konishi
Overexpression of midkine in lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats and its increase with progression.
Carcinogenesis 1999;20(3):465-9.
1999: Toru Morishita; Yoshizumi Miyauchi; Yoshio Mii; S Miura; Kanya Honoki; M Aoki; Akira Kido; M Yoshimoto; S Tamai; Masahiro Tsutsumi; Yoichi Konishi
Delay in administration of CDDP until completion of AGM-1470 treatment enhances antimetastatic and antitumor effects.
Clinical & experimental metastasis 1999;17(1):15-8.
1998: Yoichi Konishi; Masahiro Tsutsumi; D S Longnecker
Mechanistic analysis and chemoprevention of pancreatic carcinogenesis.
Pancreas 1998;17(4):334-40.
1998: Akira Kido; Toshifumi Tsujiuchi; Toru Morishita; Masahiro Tsutsumi; M Takahama; Yoshizumi Miyauchi; Yoshio Mii; S Tamai; Yoichi Konishi
Telomerase activity correlates with growth of transplantable osteosarcomas in rats treated with cis-diammine dichloroplatinum or the angiogenesis inhibitor AGM-1470.
Japanese journal of cancer research : Gann 1998;89(10):1074-81.
1998: K Iki; Toshifumi Tsujiuchi; T Majima; H Sakitani; Masahiro Tsutsumi; M Takahama; M Yoshimoto; Dai Nakae; Tsukasa Tsunoda; Yoichi Konishi
Increased telomerase activity in intrahepatic cholangiocellular carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Cancer letters 1998;131(2):185-90.
1998: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Yoichi Konishi
Telomerase activity in experimental animal tumors.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1998;50(4-6):371-4.
1998: Kanya Honoki; Toshio Mori; Masahiro Tsutsumi; Toshifumi Tsujiuchi; Akira Kido; Toru Morishita; Yoshizumi Miyauchi; Y Dohi; Yoshio Mii; S Tamai; Yoichi Konishi
Heterogeneous pattern of gene expression in cloned cell lines established from a rat transplantable osteosarcoma lung metastatic nodule.
Cancer letters 1998;127(1-2):221-8.
1998: H Sakitani; Toshifumi Tsujiuchi; K Kobitsu; Akira Kido; K Iki; M Takahama; M Nakamura; T Sakaki; Dai Nakae; Yoichi Konishi; Masahiro Tsutsumi
Increased telomerase activity and absence of p53 mutation in oligoastrocytomas induced by N-ethyl-N-nitrosourea in rats.
Cancer letters 1998;126(2):157-64.
1998: Yoichi Konishi; Masahiro Tsutsumi; Toshifumi Tsujiuchi
Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters.
Pancreas 1998;16(3):300-6.
1998: M Takahama; Masahiro Tsutsumi; Toshifumi Tsujiuchi; Akira Kido; E Okajima; K Nezu; T Tojo; Keiji Kushibe; S Kitamura; Yoichi Konishi
Frequent expression of the vascular endothelial growth factor in human non-small-cell lung cancers.
Japanese journal of clinical oncology 1998;28(3):176-81.
1998: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Akira Kido; M Takahama; H Sakitani; K Iki; Yasutaka Sasaki; Ayumi Denda; Yoichi Konishi
Induction of telomerase activity during regeneration after partial hepatectomy in the rat.
Cancer letters 1998;122(1-2):115-20.
1998: E Okajima; Masahiro Tsutsumi; S Ozono; H Akai; Ayumi Denda; H Nishino; S Oshima; H Sakamoto; Yoichi Konishi
Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl)nitrosamine initiation.
Japanese journal of cancer research : Gann 1998;89(1):22-6.
1998: T Majima; Masahiro Tsutsumi; H Nishino; Tsukasa Tsunoda; Yoichi Konishi
Inhibitory effects of beta-carotene, palm carotene, and green tea polyphenols on pancreatic carcinogenesis initiated by N-nitorsobis(2-oxopropyl)amine in Syrian golden hamsters.
Pancreas 1998;16(1):13-8.
1997: Masahiro Tsutsumi; Toshifumi Tsujiuchi; O Ishikawa; T Majima; M Yoshimoto; Y Sasaki; T Fukuda; H Oohigashi; Yoichi Konishi
Increased telomerase activities in human pancreatic duct adenocarcinomas.
Japanese journal of cancer research : Gann 1997;88(10):971-6.
1997: Ayumi Denda; T Endoh; Wakashi Kitayama; Q Tang; O Noguchi; Y Kobayashi; H Akai; E Okajima; Toshifumi Tsujiuchi; Masahiro Tsutsumi; Dai Nakae; Yoichi Konishi
Inhibition by piroxicam of oxidative DNA damage, liver cirrhosis and development of enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats.
Carcinogenesis 1997;18(10):1921-30.
1997: T Majima; Toshifumi Tsujiuchi; Masahiro Tsutsumi; Tsukasa Tsunoda; Yoichi Konishi
Mutations of K-ras but not p53 genes in biliary duct and pancreatic duct carcinomas induced in hamsters by cholecystoduodenostomy with dissection of the common duct followed by N-nitrosobis(2-oxopropyl)amine.
Cancer letters 1997;118(1):47-53.
1997: Toru Morishita; Yoshio Mii; Yoshizumi Miyauchi; S Miura; Kanya Honoki; M Aoki; Akira Kido; S Tamai; Masahiro Tsutsumi; Yoichi Konishi
Efficacy of CDDP and AGM-1470 chemotherapy against lung metastasis in rat osteosarcoma depends on the timing of combined administration.
Japanese journal of clinical oncology 1997;27(4):236-9.
1997: Akira Kido; Toshifumi Tsujiuchi; Masahiro Tsutsumi; M Takahama; Yoshizumi Miyauchi; Yoshio Mii; S Tamai; Yoichi Konishi
Increased telomerase activity is not directly related to metastatic potential in rat transplantable osteosarcomas.
Cancer letters 1997;117(1):67-71.
1997: E Okajima; S Ozono; T Endo; T Majima; Masahiro Tsutsumi; T Fukuda; H Akai; Ayumi Denda; Y Hirao; E Okajima; H Nishino; Z Nir; Yoichi Konishi
Chemopreventive efficacy of piroxicam administered alone or in combination with lycopene and beta-carotene on the development of rat urinary bladder carcinoma after N-butyl-N-(4-hydroxybutyl)nitrosamine treatment.
Japanese journal of cancer research : Gann 1997;88(6):543-52.
1997: Dai Nakae; Y Kobayashi; H Akai; N Andoh; H Satoh; K Ohashi; Masahiro Tsutsumi; Yoichi Konishi
Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine.
Cancer research 1997;57(7):1281-7.
1997: K Kobitsu; Masahiro Tsutsumi; Toshifumi Tsujiuchi; F Suzuki; Akira Kido; E Okajima; T Fukuda; T Sakaki; Yoichi Konishi
Shortened telomere length and increased telomerase activity in hamster pancreatic duct adenocarcinomas and cell lines.
Molecular carcinogenesis 1997;18(3):153-9.
1997: Akira Kido; Toshifumi Tsujiuchi; Masahiro Tsutsumi; M Takahama; E Okajima; K Kobitsu; Yoshizumi Miyauchi; Yoshio Mii; S Tamai; Yoichi Konishi
p53 mutation and absence of mdm2 amplification and Ki-ras mutation in 4-hydroxyamino quinoline 1-oxide induced transplantable osteosarcomas in rats.
Cancer letters 1997;112(1):5-10.
1997: E Okajima; Masahiro Tsutsumi; E Okajima; Yoichi Konishi
Cripto expression in human urological tumors.
Cancer letters 1997;111(1-2):67-70.
1996: Toshifumi Tsujiuchi; Akira Kido; Dai Nakae; M Takahama; T Majima; K Kobitsu; E Okajima; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
Infrequent Ki-ras and an absence of p53 mutations in hepatocellular carcinomas induced by a choline deficient L-amino acid defined diet in rats.
Cancer letters 1996;108(1):137-41.
1996: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Akira Kido; K Kobitsu; M Takahama; T Majima; Ayumi Denda; Dai Nakae; Yoichi Konishi
Increased telomerase activity in hyperplastic nodules and hepatocellular carcinomas induced by a choline-deficient L-amino acid-defined diet in rats.
Japanese journal of cancer research : Gann 1996;87(11):1111-5.
1996: K Ohashi; Masahiro Tsutsumi; Toshifumi Tsujiuchi; K Kobitsu; E Okajima; Y Nakajima; H Nakano; M Takahashi; Y Mori; Yoichi Konishi
Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis caused by a colchicine-induced cell cycle disturbance in partially hepatectomized rats.
Cancer research 1996;56(15):3474-9.
1996: E Okajima; T Fukuda; S Okita; Masahiro Tsutsumi; Y Hirao; E Okajima; Yoichi Konishi
Infrequent somatic alteration of p16/MTS1 in human primary superficial bladder cancers.
Cancer letters 1996;103(2):227-31.
1996: E Kobayashi; Toshifumi Tsujiuchi; Dai Nakae; Y Mizumoto; N Andoh; T Endoh; H Kitada; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
Inhibitory effects of N,N'-diphenyl-p-phenylenediamine on the early stage of the enhanced hepatocarcinogenesis caused by coadministration of ethionine and a choline-deficient L-amino acid-defined diet in rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1996;48(4):275-82.
1996: K Ohashi; Masahiro Tsutsumi; K Kobitsu; T Fukuda; Toshifumi Tsujiuchi; E Okajima; S Ko; Y Nakajima; H Nakano; Yoichi Konishi
Shortened telomere length in hepatocellular carcinomas and corresponding background liver tissues of patients infected with hepatitis virus.
Japanese journal of cancer research : Gann 1996;87(5):419-22.
1996: H Kitada; Masahiro Tsutsumi; Toshifumi Tsujiuchi; M Takahama; T Fukuda; N Narita; Y Konsihi
Frequent mutations of Ki-ras but no mutations of Ha-ras and p53 in lung lesions induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Molecular carcinogenesis 1996;15(4):276-83.
1996: Masahiro Tsutsumi; K Ohashi; Toshifumi Tsujiuchi; E Kobayashi; K Kobitsu; H Kitada; T Majima; E Okajima; T Endoh; K Hasegawa; T Mori; Yoichi Konishi
Disturbance of the cell cycle with colchicine enhances the growth advantage of diethylnitrosamine-initiated hepatocytes in rats.
Japanese journal of cancer research : Gann 1996;87(1):5-9.
1995: Toshifumi Tsujiuchi; E Kobayashi; Dai Nakae; Y Mizumoto; N Andoh; H Kitada; K Ohashi; T Fukuda; Akira Kido; Masahiro Tsutsumi
Prevention by methionine of enhancement of hepatocarcinogenesis by coadministration of a choline-deficient L-amino acid-defined diet and ethionine in rats.
Japanese journal of cancer research : Gann 1995;86(12):1136-42.
1995: K Yamamoto; Masahiro Tsutsumi; E Kobayashi; T Endoh; O Noguchi; E Okajima; Ayumi Denda; Y Mori; Yoichi Konishi
Initiation of hepatocarcinogenesis by endogenously formed N-nitrosobis(2-hydroxypropyl)amine, N-nitrosodiethanolamine and N-nitroso-2,6-dimethylmorpholine in rats.
Carcinogenesis 1995;16(11):2633-6.
1995: S Okita; Masahiro Tsutsumi; M Onji; Yoichi Konishi
p53 mutation without allelic loss and absence of mdm-2 amplification in a transplantable hamster pancreatic ductal adenocarcinoma and derived cell lines but not primary ductal adenocarcinomas in hamsters.
Molecular carcinogenesis 1995;13(4):266-71.
1995: Toru Morishita; Yoshio Mii; Yoshizumi Miyauchi; S Miura; Kanya Honoki; M Aoki; Akira Kido; S Tamai; Masahiro Tsutsumi; Yoichi Konishi
Efficacy of the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (AGM-1470) on osteosarcoma growth and lung metastasis in rats.
Japanese journal of clinical oncology 1995;25(2):25-31.
1995: Masahiro Tsutsumi; O Noguchi; S Okita; K Horiguchi; E Kobayashi; K Tamura; Toshifumi Tsujiuchi; Ayumi Denda; Yoichi Konishi; K Iimura
Inhibitory effects of sulfation inhibitors on initiation of pancreatic ductal carcinogenesis by N-nitrosobis(2-oxopropyl)amine in hamsters.
Carcinogenesis 1995;16(3):457-9.
1994: K Ohashi; Masahiro Tsutsumi; Y Nakajima; O Noguchi; S Okita; H Kitada; Toshifumi Tsujiuchi; E Kobayashi; H Nakano; Yoichi Konishi
High rates of Ki-ras point mutation in both intra- and extra-hepatic cholangiocarcinomas.
Japanese journal of clinical oncology 1994;24(6):305-10.
1994: T Mori; Masahiro Tsutsumi; O Noguchi; K Horiguchi; K Hohnoki; S Okita; F Suzuki; Yoichi Konishi
Characterization of three cloned cell lines from a N-nitrosobis(2-hydroxypropyl)amine-induced transplantable hamster pancreatic ductal adenocarcinoma.
International journal of pancreatology : official journal of the International Association of Pancreatology 1994;16(2-3):171-7.
1994: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Kanya Honoki; K Horiguchi; E Kobayashi; Ayumi Denda; Yoichi Konishi
Effects of novobiocin on the induction of gamma-glutamyltranspeptidase positive foci in the liver of rats treated with diethylnitrosamine.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1994;46(2):115-8.
1994: H Maruyama; T Amanuma; Masahiro Tsutsumi; Toshifumi Tsujiuchi; K Horiguchi; Ayumi Denda; Yoichi Konishi
Inhibition by catechol and di(2-ethylhexyl)phthalate of pancreatic carcinogenesis after initiation with N-nitrosobis(2-hydroxypropyl)amine in Syrian hamsters.
Carcinogenesis 1994;15(6):1193-6.
1994: Hitoshi Yoshiji; Dai Nakae; R Sugiya; Y Mizumoto; Masahiro Tsutsumi; K Hiriguchi; Y Yokose; R Sakurai; H Fukui; T Tsujii
Spontaneous passage of a colon cast in the absence of abdominal aneurysm.
Journal of gastroenterology 1994;29(1):80-3.
1994: Masahiro Tsutsumi; W Yasui; A Naito; K Ohashi; E Kobayashi; O Noguchi; K Horiguchi; S Okita; Toshifumi Tsujiuchi; H Kitada
Expression of cripto in human pancreatic tumors.
Japanese journal of cancer research : Gann 1994;85(2):118-21.
1993: Masahiro Tsutsumi; S Kondoh; O Noguchi; K Horiguchi; E Kobayashi; S Okita; K Ohashi; Kanya Honoki; Toshifumi Tsujiuchi; Yoichi Konishi
K-ras gene mutation in early ductal lesions induced in a rapid production model for pancreatic carcinomas in Syrian hamsters.
Japanese journal of cancer research : Gann 1993;84(11):1101-5.
1993: Kanya Honoki; Masahiro Tsutsumi; Yoshizumi Miyauchi; Yoshio Mii; Toshifumi Tsujiuchi; Toru Morishita; S Miura; M Aoki; E Kobayashi; S Tamai
Increased expression of nucleoside diphosphate kinase/nm23 and c-Ha-ras mRNA is associated with spontaneous lung metastasis in rat-transplantable osteosarcomas.
Cancer research 1993;53(20):5038-42.
1993: Masahiro Tsutsumi; Y Murakami; S Kondoh; Toshifumi Tsujiuchi; K Hohnoki; K Horiguchi; O Noguchi; E Kobayashi; S Okita; T Sekiya
Comparison of K-ras oncogene activation in pancreatic duct carcinomas and cholangiocarcinomas induced in hamsters by N-nitrosobis(2-hydroxypropyl)amine.
Japanese journal of cancer research : Gann 1993;84(9):956-60.
1993: Q Tang; Ayumi Denda; Toshifumi Tsujiuchi; Masahiro Tsutsumi; T Amanuma; Y Murata; H Maruyama; Yoichi Konishi
Inhibitory effects of inhibitors of arachidonic acid metabolism on the evolution of rat liver preneoplastic foci into nodules and hepatocellular carcinomas with or without phenobarbital exposure.
Japanese journal of cancer research : Gann 1993;84(2):120-7.
1993: Kanya Honoki; Y Dohi; S Tabata; Yoshio Mii; Yoshizumi Miyauchi; Masahiro Tsutsumi; Toshifumi Tsujiuchi; Toru Morishita; S Miura; T Moriyama
Correlation between lack of bone Gla protein mRNA expression in rat transplantable osteosarcomas and expression of both c-fos and c-jun proto-oncogenes.
Molecular carcinogenesis 1993;7(2):111-5.
1993: Ayumi Denda; Q Tang; Toshifumi Tsujiuchi; Masahiro Tsutsumi; T Amanuma; Y Murata; K Tamura; K Horiguchi; Dai Nakae; Yoichi Konishi
Effects of oxidative stress induced by redox-enzyme modulation on the progression stage of rat hepatocarcinogenesis.
Carcinogenesis 1993;14(1):95-101.
1992: Toshifumi Tsujiuchi; Masahiro Tsutsumi; K Uchida; Kanya Honoki; S Kondoh; Ayumi Denda; M Miwa; Yoichi Konishi
Delayed DNA synthesis induced by 3-aminobenzamide in partially hepatectomized liver of rats.
Japanese journal of cancer research : Gann 1992;83(9):985-8.
1992: H Maruyama; T Amanuma; Y Takashima; Hitoshi Yoshiji; Dai Nakae; Masahiro Tsutsumi; Toshifumi Tsujiuchi; Ayumi Denda; Yoichi Konishi
Possible enhancing effect of the immunosuppressive agent, 6-mercaptopurine(6-MP) on focal lesion development in cirrhotic liver induced by carbon tetrachloride but not furfural in F344 rats.
Carcinogenesis 1992;13(8):1365-9.
1992: T Amanuma; H Maruyama; Toshifumi Tsujiuchi; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
Lack of modifying effects of 6-mercaptopurine in a medium term bioassay system for liver carcinogenesis using male F344 rats.
Cancer letters 1992;64(2):99-107.
1992: Yoichi Konishi; Ayumi Denda; K Uchida; Y Emi; H Ura; Y Yokose; K Shiraiwa; Masahiro Tsutsumi
Chronic toxicity carcinogenicity studies of triethanolamine in B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1992;18(1):25-9.
1992: Kanya Honoki; Masahiro Tsutsumi; Toshifumi Tsujiuchi; S Kondoh; K Shiraiwa; Yoshizumi Miyauchi; Yoshio Mii; S Tamai; Yoichi Konishi; George Bowden
Expression of the transin, c-fos, and c-jun genes in rat transplantable osteosarcomas and malignant fibrous histiocytomas.
Molecular carcinogenesis 1992;6(2):122-8.
1991: Toshifumi Tsujiuchi; K Mizumoto; Masahiro Tsutsumi; Ayumi Denda; T Amanuma; S Kondoh; Yoichi Konishi
Effects of 3-aminobenzamide on the post-initiation phase of N-nitrosobis(2-oxopropyl)amine induced pancreatic carcinogenesis in Syrian hamsters.
Cancer letters 1991;61(1):61-6.
1991: H Maruyama; T Amanuma; Dai Nakae; Masahiro Tsutsumi; S Kondo; Toshifumi Tsujiuchi; Ayumi Denda; Yoichi Konishi
Effects of catechol and its analogs on pancreatic carcinogenesis initiated by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters.
Carcinogenesis 1991;12(7):1331-4.
1991: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Ayumi Denda; T Amanuma; S Kondoh; K Kamino; Yoichi Konishi
Effects of 3-aminobenzamide on induction of multiorgan carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine in hamsters.
Japanese journal of cancer research : Gann 1991;82(7):793-9.
1991: T Amanuma; K Mizumoto; Masahiro Tsutsumi; Toshifumi Tsujiuchi; S Kitazawa; K Hasegawa; Ayumi Denda; H Maruyama; Yoichi Konishi
Initiating activity of diethylnitrosamine in a rapid production model for pancreatic carcinomas in Syrian hamsters.
Japanese journal of cancer research : Gann 1991;82(6):632-7.
1991: Ayumi Denda; K M Sai; Q Tang; Toshifumi Tsujiuchi; Masahiro Tsutsumi; T Amanuma; Y Murata; Dai Nakae; H Maruyama; Y Kurokawa
Induction of 8-hydroxydeoxyguanosine but not initiation of carcinogenesis by redox enzyme modulations with or without menadione in rat liver.
Carcinogenesis 1991;12(4):719-26.
1991: Yoshio Mii; Yoshizumi Miyauchi; T Yoshikawa; Kanya Honoki; M Aoki; Masahiro Tsutsumi; H Maruyama; M Funauchi; Y Konishi; S Tamai
Ultrastructural lipid and glycoconjugate cytochemistry of membranous lipodystrophy (Nasu-Hakola disease).
Virchows Archiv. A, Pathological anatomy and histopathology 1991;419(2):137-42.
1991: Yoichi Konishi; K Yamamoto; H Eimoto; Masahiro Tsutsumi; M Sugimura; H Nii; Y Mori
Carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in rats.
IARC scientific publications 1991;(105):318-21.
1991: Yoshizumi Miyauchi; Yoshio Mii; K Hohnoki; S Tamai; H Maruyama; Masahiro Tsutsumi; K Shiraiwa; Yoichi Konishi
Metastatic potential of malignant fibrous histiocytoma of myxoid or giant-cell subtype in rats.
Experimental pathology 1991;43(3-4):129-39.
1990: Toshifumi Tsujiuchi; Masahiro Tsutsumi; Ayumi Denda; S Kondoh; Dai Nakae; H Maruyama; Yoichi Konishi
Possible involvement of poly ADP-ribosylation in phenobarbital promotion of rat hepatocarcinogenesis.
Carcinogenesis 1990;11(10):1783-7.
1990: S Kitazawa; K Mizumoto; T Amanuma; Masahiro Tsutsumi; H Maruyama; Yoichi Konishi
Inhibition of pancreatic hepatocyte induction in hamsters treated sequentially with ethionine, a protein-free diet and then methionine by prior N-nitrosobis-(2-oxopropyl)amine administration.
Acta pathologica japonica 1990;40(8):562-7.
1990: Yoichi Konishi; K Mizumoto; S Kitazawa; Toshifumi Tsujiuchi; Masahiro Tsutsumi; T Kamano
Early ductal lesions of pancreatic carcinogenesis in animals and humans.
International journal of pancreatology : official journal of the International Association of Pancreatology 1990;7(1-3):83-9.
1990: S Kitazawa; Ayumi Denda; Masahiro Tsutsumi; Toshifumi Tsujiuchi; K Hasegawa; K Tamura; H Maruyama; Yoichi Konishi
Enhanced preneoplastic liver lesion development under 'selection pressure' conditions after administration of deoxycholic or lithocholic acid in the initiation phase in rats.
Carcinogenesis 1990;11(8):1323-8.
1990: H Maruyama; Y Takashima; Y Murata; Dai Nakae; H Eimoto; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
Lack of hepatocarcinogenic potential of acetaminophen in rats with liver damage associated with a choline-devoid diet.
Carcinogenesis 1990;11(6):895-901.
1990: K Mizumoto; Masahiro Tsutsumi; S Kitazawa; Ayumi Denda; Yoichi Konishi
Usefulness of rapid production model for pancreatic carcinoma in male hamsters.
Cancer letters 1990;49(3):211-5.
1990: Masahiro Tsutsumi; K Mizumoto; T Tsujiuchi; H Maruyama; M Koizumi; T Inagaki; M Toyokawa; Yoichi Konishi
Serous cystadenoma of the esophagus.
Acta pathologica japonica 1990;40(2):153-5.
1989: Ayumi Denda; H Ura; Toshifumi Tsujiuchi; Masahiro Tsutsumi; H Eimoto; Y Takashima; S Kitazawa; T Kinugasa; Yoichi Konishi
Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis.
Carcinogenesis 1989;10(10):1929-35.
1989: K Yamamoto; A Nakajima; H Eimoto; Masahiro Tsutsumi; H Maruyama; Ayumi Denda; H Nii; Y Mori; Yoichi Konishi
Carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in rats administered bis(2-hydroxypropyl)amine and sodium nitrite.
Carcinogenesis 1989;10(9):1607-11.
1989: K Mizumoto; S Ito; S Kitazawa; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
Inhibitory effect of butylated hydroxyanisole administration on pancreatic carcinogenesis in Syrian hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis 1989;10(8):1491-4.
1989: K Mizumoto; S Kitazawa; S Ito; Y Takashima; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
Cycles of repeated augmentation pressure in rapid production of pancreatic and cholangiocellular carcinomas in hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis 1989;10(8):1457-9.
1989: K Yamamoto; H Eimoto; Y Takashima; Masahiro Tsutsumi; H Maruyama; Ayumi Denda; Y Mori; Yoichi Konishi
Initiation activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in the rat liver.
Cancer letters 1989;45(3):221-5.
1989: Ayumi Denda; Masahiro Tsutsumi; Toshifumi Tsujiuchi; H Eimoto; Yoichi Konishi; S Sato
Induction of rat liver gamma-glutamyltranspeptidase-positive foci by oral administration of 1-nitropyrene.
Cancer letters 1989;45(1):21-6.
1989: Yoshizumi Miyauchi; Yoshio Mii; T Kadono; Y Ueda; S Miura; K Hohnoki; K Masuhara; Masahiro Tsutsumi; K Shiraiwa; H Maruyama
[Transplantable osteosarcomas in rats. I. The growth behavior of spontaneous and 4-HAQO induced osteosarcomas in rats].
Nihon Seikeigeka Gakkai zasshi 1989;63(4):282-95.
1989: Yoshio Mii; Yoshizumi Miyauchi; K Hohnoki; H Maruyama; Masahiro Tsutsumi; Kayoko Dohmae; S Tamai; Yoichi Konishi; T Yamanouchi
Neural crest origin of clear cell sarcoma of tendons and aponeuroses. Ultrastructural and enzyme cytochemical study of human and nude mouse-transplanted tumours.
Virchows Archiv. A, Pathological anatomy and histopathology 1989;415(1):51-60.
1988: K Mizumoto; Masahiro Tsutsumi; Ayumi Denda; Yoichi Konishi
Rapid production of pancreatic carcinoma by initiation with N-nitroso-bis(2-oxopropyl)amine and repeated augmentation pressure in hamsters.
Journal of the National Cancer Institute 1988;80(19):1564-7.
1988: H Eimoto; Masahiro Tsutsumi; A Nakajima; K Yamamoto; Y Takashima; H Maruyama; Yoichi Konishi
Expression of the glutathione S-transferase placental form in human lung carcinomas.
Carcinogenesis 1988;9(12):2325-7.
1988: K Uchida; S Takahashi; K Fujiwara; K Ueda; Dai Nakae; Y Emi; Masahiro Tsutsumi; K Shiraiwa; T Ohnishi; Yoichi Konishi
Preventive effect of 3-aminobenzamide on the reduction of NAD levels in rat liver following administration of diethylnitrosamine.
Japanese journal of cancer research : Gann 1988;79(10):1094-100.
1988: K Mizumoto; S Kitazawa; T Eguchi; A Nakajima; Masahiro Tsutsumi; S Ito; A Danda; Yoichi Konishi
Modulation of N-nitrosobis(2-hydroxypropyl)amine-induced carcinogenesis by clofibrate in hamsters.
Carcinogenesis 1988;9(8):1421-5.
1988: Yoshio Mii; Masahiro Tsutsumi; K Shiraiwa; Yoshizumi Miyauchi; K Hohnoki; H Maruyama; H Ogushi; K Masuhara; Yoichi Konishi
Transplantable osteosarcomas with high lung metastatic potential in Fischer 344 rats.
Japanese journal of cancer research : Gann 1988;79(5):589-92.
1988: K Yamamoto; Y Yokose; A Nakajima; H Eimoto; K Shiraiwa; K Tamura; Masahiro Tsutsumi; Yoichi Konishi
Comparative histochemical investigation of the glutathione S-transferase placental form and gamma-glutamyltranspeptidase during N-nitrosobis(2-hydroxypropyl)amine-induced lung carcinogenesis in rats.
Carcinogenesis 1988;9(3):399-404.
1988: K Mizumoto; T Inagaki; M Koizumi; M Uemura; M Ogawa; S Kitazawa; Masahiro Tsutsumi; M Toyokawa; Yoichi Konishi
Early pancreatic duct adenocarcinoma.
Human pathology 1988;19(2):242-4.
1988: Ayumi Denda; Masahiro Tsutsumi; Y Yokose; H Eimoto; Yoichi Konishi
Effects of 3-aminobenzamide on the induction of gamma-glutamyl-transpeptidase-positive foci by various chemicals in rat liver.
Cancer letters 1988;39(1):29-36.
1987: H Ura; Ayumi Denda; Y Yokose; Masahiro Tsutsumi; Yoichi Konishi
Effect of vitamin E on the induction and evolution of enzyme-altered foci in the liver of rats treated with diethylnitrosamine.
Carcinogenesis 1987;8(11):1595-600.
1987: S Takahashi; Masahiro Tsutsumi; Dai Nakae; Ayumi Denda; T Kinugasa; Yoichi Konishi
Persistent effect of a low dose of preadministered diethylnitrosamine on the induction of enzyme-altered foci in rat liver.
Carcinogenesis 1987;8(4):509-13.
1986: Y Yokose; H Maruyama; Masahiro Tsutsumi; K Uchida; K Shiraiwa; Yoichi Konishi
Ileal atresia and absence of appendix.
Acta pathologica japonica 1986;36(9):1403-10.
1986: H Ura; T Makino; S Ito; Masahiro Tsutsumi; T Kinugasa; T Kamano; H Ichimiya; Yoichi Konishi
Combined effects of cholecystectomy and lithocholic acid on pancreatic carcinogenesis of N-nitrosobis(2-hydroxypropyl)amine in Syrian golden hamsters.
Cancer research 1986;46(9):4782-6.
1986: Yoichi Konishi; S Takahashi; Dai Nakae; K Uchida; Masahiro Tsutsumi; K Shiraiwa; Ayumi Denda
Possible model of liver carcinogenesis using inhibitors of NAD+ ADP ribosyl transferase in rats.
Toxicologic pathology 1986;14(4):483-8.
1985: Ayumi Denda; Y Mori; Y Yokose; K Uchida; Y Murata; T Makino; Masahiro Tsutsumi; Y Konishi
4-Hydroxyaminoquinoline 1-oxide metabolism and DNA adducts in the early stage of tumorigenesis in rats: comparison of target organ pancreas with non-target organ liver.
Chemico-biological interactions 1985;56(2-3):125-43.