FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Burkhard Tümmler

Research Profile

Disorders

Living Beings

Chemicals & Drugs

Genes & Molecular Sequences

Concepts & Ideas

Molecular Sequence Data

Physiology

Procedures

Anatomy

Lung

Co-author Network

Publications

TOP 3
Ernst-Wolfgang Kolbe; Tim Becker; Silke Hedtfeld; Stephanie Tamm; Burkhard Tümmler; Frauke Stanke
CLCA4 variants determine the manifestation of the cystic fibrosis basic defect in the intestine.
Colin F Davenport; Burkhard Tümmler
Advances in computational analysis of metagenome sequences.
Jens Klockgether; Peter Kubesch; Meike Lingner; Liliana Luciano; Norbert Miethke; Prabhakar Salunkhe; Dietmar Schomburg; Yu-Sing Bohn; Inka Brockhausen; Nina Cramer; Colin F Davenport; Leo Eberl; Joachim Greipel; Christian Herrmann; Susanne Herrmann; Sonja Horatzek; Maria Wehsling; Lutz Wiehlmann; Burkhard Tümmler
Intraclonal diversity of the Pseudomonas aeruginosa cystic fibrosis airway isolates TBCF10839 and TBCF121838: distinct signatures of transcriptome, proteome, metabolome, adherence and pathogenicity despite an almost identical genome sequence.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Burkhard Tümmler (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Ernst-Wolfgang Kolbe; Tim Becker; Silke Hedtfeld; Stephanie Tamm; Burkhard Tümmler; Frauke Stanke
CLCA4 variants determine the manifestation of the cystic fibrosis basic defect in the intestine.
European journal of human genetics : EJHG 2013;21(6):691-4.
2013: Colin F Davenport; Burkhard Tümmler
Advances in computational analysis of metagenome sequences.
Environmental microbiology 2013;15(1):1-5.
2013: Jens Klockgether; Peter Kubesch; Meike Lingner; Liliana Luciano; Norbert Miethke; Prabhakar Salunkhe; Dietmar Schomburg; Yu-Sing Bohn; Inka Brockhausen; Nina Cramer; Colin F Davenport; Leo Eberl; Joachim Greipel; Christian Herrmann; Susanne Herrmann; Sonja Horatzek; Maria Wehsling; Lutz Wiehlmann; Burkhard Tümmler
Intraclonal diversity of the Pseudomonas aeruginosa cystic fibrosis airway isolates TBCF10839 and TBCF121838: distinct signatures of transcriptome, proteome, metabolome, adherence and pathogenicity despite an almost identical genome sequence.
Environmental microbiology 2013;15(1):191-210.
2012: Katrin Anne Becker; Erich Gulbins; Brian Henry; Burkhard Tümmler; Regan Ziobro; Heike Grassmé
Role of CD95 in pulmonary inflammation and infection in cystic fibrosis.
Journal of molecular medicine (Berlin, Germany) 2012;90(9):1011-23.
2012: Susanne I Fuchs; Frank Ahrens; Johannes Eder; Helmut Ellemunter; Matthias Griese; Jörg Grosse-Onnebrink; Andrea Jobst; Uwe Mellies; Ernst Rietschel; Jan Ripper; Doris Staab; Burkhard Tümmler; Susanne Zeidler; Monika Gappa
Feasibility and variability of measuring the Lung Clearance Index in a multi-center setting.
Pediatric pulmonology 2012;47(7):649-57.
2012: Lutz Wiehlmann; Nina Cramer; Silke Hedtfeld; Jutta Ulrich; Hartmut Weissbrodt; Burkhard Tümmler
Effective prevention of Pseudomonas aeruginosa cross-infection at a cystic fibrosis centre - results of a 10-year prospective study.
International journal of medical microbiology : IJMM 2012;302(2):69-77.
2012: Nina Cramer; Niels Høiby; Stephanie Tamm; Oana Ciofu; Lutz Wiehlmann; Burkhard Tümmler
Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis.
PloS one 2012;7(11):e50731.
2012: Jenny Bode; Pavel Dutow; Silke Glage; Katrin Janik; Robert Laudeley; Antje Munder; Konrad W Sachse; Kirsten Sommer; Burkhard Tümmler; Andreas Klos
A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci.
PloS one 2012;7(11):e50327.
2012: Colin F Davenport; Benedikt Friedrich; Burim Kameri; Svea Kokott; Jens Neugebauer; Malte Paetow; Björn Siekmann; Burkhard Tümmler; Matthias Wieding-Drewes; Markus Wienhöfer; Stefan Wolf; Volker Ahlers; Nils Beckmann; Frauke Sprengel
Genometa--a fast and accurate classifier for short metagenomic shotgun reads.
PloS one 2012;7(8):e41224.
2012: Andrea van Barneveld; Isabell Zander; Manfred Ballmann; Nico Derichs; Rebecca Hyde; Marcus Krüger; Florian Länger; André Simon; Burkhard Tümmler
Immunochemical analysis of mutant CFTR in lung explants.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;30(3):587-95.
2012: Melanie Handschick; Silke Hedtfeld; Burkhard Tümmler
Frequency of the hyperactive W493R ENaC variant in carriers of a CFTR mutation.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2012;11(1):53-5.
2011: Heike Labenski; Tim Becker; Silke Hedtfeld; Burkhard Tümmler; Frauke Stanke
Initial interrogation, confirmation and fine mapping of modifying genes: STAT3, IL1B and IFNGR1 determine cystic fibrosis disease manifestation.
European journal of human genetics : EJHG 2011;19(12):1281-8.
2011: Florian Wölbeling; Gesine Hansen; Christian Hennig; Tanja Kerber-Momot; Antje Munder; Detlef Neumann; Burkhard Tümmler; Ulrich Baumann
Lung function and inflammation during murine Pseudomonas aeruginosa airway infection.
Immunobiology 2011;216(8):901-8.
2011: Nina Cramer; Colin F Davenport; Jens Klockgether; Mario Schmidt; Kristie Wrasman; Burkhard Tümmler
Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs.
Environmental microbiology 2011;13(7):1690-704.
2011: Robert Bals; Dominique Hubert; Burkhard Tümmler
Antibiotic treatment of CF lung disease: from bench to bedside.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2011;10 Suppl 2():S146-51.
2011: Sarah Frank; Jens Klockgether; Petra Hagendorf; Robert Geffers; Ulrike Schöck; Thomas Pohl; Colin F Davenport; Burkhard Tümmler
Pseudomonas putida KT2440 genome update by cDNA sequencing and microarray transcriptomics.
Environmental microbiology 2011;13(5):1309-26.
2011: Sarah Frank; Frank Schmidt; Jens Klockgether; Colin F Davenport; Manuela Gesell Salazar; Uwe Völker; Burkhard Tümmler
Functional genomics of the initial phase of cold adaptation of Pseudomonas putida KT2440.
FEMS microbiology letters 2011;318(1):47-54.
2011: Piotr Bielecki; Justyna Glik; Marek Kawecki; Holger Loessner; Mariusz Nowak; Jacek Puchałka; Burkhard Tümmler; Siegfried Weiss; Melissa L Wos-Oxley; Vítor A P Martins dos Santos
In-vivo expression profiling of Pseudomonas aeruginosa infections reveals niche-specific and strain-independent transcriptional programs.
PloS one 2011;6(9):e24235.
2011: Frauke Stanke; Silke Hedtfeld; Tim Becker; Burkhard Tümmler
An association study on contrasting cystic fibrosis endophenotypes recognizes KRT8 but not KRT18 as a modifier of cystic fibrosis disease severity and CFTR mediated residual chloride secretion.
BMC medical genetics 2011;12():62.
2011: Frauke Stanke; Tim Becker; Vinod Kumar; Silke Hedtfeld; Christian Becker; Harry Cuppens; Stephanie Tamm; Jennifer Yarden; Ulrike Laabs; Benny Siebert; Luis Fernandez; Milan Macek Jr.; Dragica Radojkovic; Manfred Ballmann; Joachim Greipel; Jean-Jacques Cassiman; Thomas F Wienker; Burkhard Tümmler
Genes that determine immunology and inflammation modify the basic defect of impaired ion conductance in cystic fibrosis epithelia.
Journal of medical genetics 2011;48(1):24-31.
2010: Katrin Anne Becker; Burkhard Tümmler; Erich Gulbins; Heike Grassmé
Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death.
Biochemical and biophysical research communications 2010;403(3-4):368-74.
2010: Nina Cramer; Lutz Wiehlmann; Burkhard Tümmler
Clonal epidemiology of Pseudomonas aeruginosa in cystic fibrosis.
International journal of medical microbiology : IJMM 2010;300(8):526-33.
2010: Andrea van Barneveld; Frauke Stanke; Stephanie Tamm; Benny Siebert; Gudrun Brandes; Nico Derichs; Manfred Ballmann; Sibylle Junge; Burkhard Tümmler
Functional analysis of F508del CFTR in native human colon.
Biochimica et biophysica acta 2010;1802(11):1062-9.
2010: Nico Derichs; Javier Sanz; Thomas Von Kanel; Cornelia Stolpe; Antonia Zapf; Burkhard Tümmler; Sabina Gallati; Manfred Ballmann
Intestinal current measurement for diagnostic classification of patients with questionable cystic fibrosis: validation and reference data.
Thorax 2010;65(7):594-9.
2010: Colin Davenport; David W Ussery; Burkhard Tümmler
Comparative genomics of green sulfur bacteria.
Photosynthesis research 2010;104(2-3):137-52.
2010: Frauke Stanke; Tim Becker; Silke Hedtfeld; Stephanie Tamm; Thomas F Wienker; Burkhard Tümmler
Hierarchical fine mapping of the cystic fibrosis modifier locus on 19q13 identifies an association with two elements near the genes CEACAM3 and CEACAM6.
Human genetics 2010;127(4):383-94.
2010: Jens Klockgether; Antje Munder; Jens Neugebauer; Colin F Davenport; Frauke Stanke; Karen D Larbig; Stephan Heeb; Ulrike Schöck; Thomas M Pohl; Lutz Wiehlmann; Burkhard Tümmler
Genome diversity of Pseudomonas aeruginosa PAO1 laboratory strains.
Journal of bacteriology 2010;192(4):1113-21.
2010: Tanja Kerber-Momot; Damaris Leemhuis; Anke Lührmann; Antje Munder; Burkhard Tümmler; Reinhard Pabst; Thomas Tschernig
Beneficial effects of TLR-2/6 ligation in pulmonary bacterial infection and immunization with Pseudomonas aeruginosa.
Inflammation 2010;33(1):58-64.
2010: Florian Wölbeling; Antje Munder; Frauke Stanke; Burkhard Tümmler; Ulrich Baumann
Head-out spirometry accurately monitors the course of Pseudomonas aeruginosa lung infection in mice.
Respiration; international review of thoracic diseases 2010;80(4):340-6.
2010: Colin F Davenport; Burkhard Tümmler
Abundant oligonucleotides common to most bacteria.
PloS one 2010;5(3):e9841.
2009: Elza Rakhimova; Lutz Wiehlmann; Aimee L Brauer; Sanjay Sethi; Timothy F Murphy; Burkhard Tümmler
Pseudomonas aeruginosa population biology in chronic obstructive pulmonary disease.
The Journal of infectious diseases 2009;200(12):1928-35.
2009: Michael Hogardt; Jutta Ulrich; Helga Riehn-Kopp; Burkhard Tümmler
EuroCareCF quality assessment of diagnostic microbiology of cystic fibrosis isolates.
Journal of clinical microbiology 2009;47(11):3435-8.
2009: steve garvis; Antje Munder; Geneviève Ball; Sophie de Bentzmann; Lutz Wiehlmann; Jonathan J Ewbank; Burkhard Tümmler; Alain Filloux
Caenorhabditis elegans semi-automated liquid screen reveals a specialized role for the chemotaxis gene cheB2 in Pseudomonas aeruginosa virulence.
PLoS pathogens 2009;5(8):e1000540.
2009: Alessandra Bragonzi; Moira Paroni; Alessandro Nonis; Nina Cramer; Sara Montanari; Joanna Rejman; Clelia Di Serio; Gerd Döring; Burkhard Tümmler
Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence.
American journal of respiratory and critical care medicine 2009;180(2):138-45.
2009: Abul Kalam Azad; Robert Rauh; François Vermeulen; Martine Jaspers; Judit Korbmacher; Brigitte Boissier; Laurence Bassinet; Yann Fichou; Marie Des Georges; Frauke Stanke; Kris De Boeck; Lieven Dupont; Miroslava Balascáková; Lena Hjelte; Patrick Lebecque; Dragica Radojkovic; Carlo Castellani; Marianne Schwartz; Manfred Stuhrmann; Martin Schwarz; Veronika Skalicka; Isabelle de Monestrol; Emmanuelle Girodon; Claude Férec; Mireille Claustres; Burkhard Tümmler; Jean-Jacques Cassiman; Christoph Korbmacher; Harry Cuppens
Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease.
Human mutation 2009;30(7):1093-103.
2009: Colin F Davenport; Lutz Wiehlmann; Oleg Reva; Burkhard Tümmler
Visualization of Pseudomonas genomic structure by abundant 8-14mer oligonucleotides.
Environmental microbiology 2009;11(5):1092-104.
2009: Burkhard Tümmler; Frauke Stanke; Inez Bronsveld; Henk J Veeze; Manfred Ballmann
Transient correction of the basic defect in sweat glands in an individual with cystic fibrosis carrying the complex CFTR allele F508del-R553Q.
Thorax 2009;64(2):179-80.
2009: Yu-Sing Tammy Bohn; Gudrun Brandes; Elza Rakhimova; Sonja Horatzek; Prabhakar Salunkhe; Antje Munder; Andrea van Barneveld; Doris Jordan; Florian Bredenbruch; Susanne Häussler; Kathrin Riedel; Leo Eberl; Peter Østrup Jensen; Thomas Bjarnsholt; Claus Moser; Niels Hoiby; Burkhard Tümmler; Lutz Wiehlmann
Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection.
Molecular microbiology 2009;71(3):730-47.
2008: V Kumar; Tim Becker; Silke Jansen; A van Barneveld; Kaan Boztug; S Wölfl; Burkhard Tümmler; Frauke Stanke
Expression levels of FAS are regulated through an evolutionary conserved element in intron 2, which modulates cystic fibrosis disease severity.
Genes and immunity 2008;9(8):689-96.
2008: Jens Klockgether; Dieco Würdemann; Lutz Wiehlmann; Burkhard Tümmler
Transcript profiling of the Pseudomonas aeruginosa genomic islands PAGI-2 and pKLC102.
Microbiology (Reading, England) 2008;154(Pt 6):1599-604.
2008: Volker Teichgräber; Martina Ulrich; Nicole Endlich; Joachim Riethmüller; Barbara Wilker; Cheyla Conceição De Oliveira-Munding; Anna van Heeckeren; Mark L Barr; Gabriele von Kürthy; Kurt W Schmid; Michael Weller; Burkhard Tümmler; Florian Lang; Heike Grassme; Gerd Döring; Erich Gulbins
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis.
Nature medicine 2008;14(4):382-91.
2008: Oleg Reva; Burkhard Tümmler
Think big--giant genes in bacteria.
Environmental microbiology 2008;10(3):768-77.
2008: Oleg Reva; Peter F Hallin; Hanni Willenbrock; thomas sicheritz-ponten; Burkhard Tümmler; David W Ussery
Global features of the Alcanivorax borkumensis SK2 genome.
Environmental microbiology 2008;10(3):614-25.
2008: Andrea van Barneveld; Frauke Stanke; A Claass; Manfred Ballmann; Burkhard Tümmler
CFTR protein analysis of splice site mutation 2789+5 G-A.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2008;7(2):165-7.
2008: Hamilton Ganesan; Anna S Rakitianskaia; Colin F Davenport; Burkhard Tümmler; Oleg Reva
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes through oligonucleotide usage.
BMC bioinformatics 2008;9():333.
2008: Balázs Tóth; Martina Wilke; Frauke Stanke; Martina Dorsch; Silke Jansen; Dirk Wedekind; Nikoletta Charizopoulou; Alice Bot; Marion Burmester; Sabine Leonhard-Marek; Hugo R de Jonge; Hans J Hedrich; Gerhard Breves; Burkhard Tümmler
Very mild disease phenotype of congenic CftrTgH(neoim)Hgu cystic fibrosis mice.
BMC genetics 2008;9():28.
2008: Elza Rakhimova; Antje Munder; Lutz Wiehlmann; Florian Bredenbruch; Burkhard Tümmler
Fitness of isogenic colony morphology variants of Pseudomonas aeruginosa in murine airway infection.
PloS one 2008;3(2):e1685.
2008: Alicia Fajardo; Nadia Martínez-Martín; María Mercadillo; Juan-Carlos Galán; Bart Ghysels; Sandra Matthijs; Pierre Cornelis; Lutz Wiehlmann; Burkhard Tümmler; Fernando Baquero; José L Martínez
The neglected intrinsic resistome of bacterial pathogens.
PloS one 2008;3(2):e1619.
2008: Frauke Stanke; Manfred Ballmann; Inez Bronsveld; Thilo Dörk; S Gallati; Ulrike Laabs; N Derichs; M Ritzka; Heinz G Posselt; H K Harms; M Griese; H Blau; G Mastella; Jan Bijman; Henk J Veeze; Burkhard Tümmler
Diversity of the basic defect of homozygous CFTR mutation genotypes in humans.
Journal of medical genetics 2008;45(1):47-54.
2007: Lutz Wiehlmann; Antje Munder; Thorsten Adams; Mario Juhas; Harald Kolmar; Prabhakar Salunkhe; Burkhard Tümmler
Functional genomics of Pseudomonas aeruginosa to identify habitat-specific determinants of pathogenicity.
International journal of medical microbiology : IJMM 2007;297(7-8):615-23.
2007: Dieco Würdemann; Burkhard Tümmler
In silico comparison of pKLC102-like genomic islands of Pseudomonas aeruginosa.
FEMS microbiology letters 2007;275(2):244-9.
2007: Gregor Hagelueken; Lutz Wiehlmann; Thorsten M Adams; Harald Kolmar; Dirk W Heinz; Burkhard Tümmler; Wolf-Dieter Schubert
Crystal structure of the electron transfer complex rubredoxin rubredoxin reductase of Pseudomonas aeruginosa.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12276-81.
2007: Tim Becker; Silke Jansen; Stephanie Tamm; Thomas F Wienker; Burkhard Tümmler; Frauke Stanke
Transmission ratio distortion and maternal effects confound the analysis of modulators of cystic fibrosis disease severity on 19q13.
European journal of human genetics : EJHG 2007;15(7):774-8.
2007: Lutz Wiehlmann; Gerd Wagner; Nina Cramer; Benny Siebert; Peter Gudowius; Gracia Morales; Thilo Köhler; Christian van Delden; Christian Weinel; Peter Slickers; Burkhard Tümmler
Population structure of Pseudomonas aeruginosa.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):8101-6.
2007: Sara Montanari; Antonio Oliver; Paola Salerno; Ana Mena; Giovanni Bertoni; Burkhard Tümmler; Lisa Cariani; Massimo Conese; Gerd Döring; Alessandra Bragonzi
Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis.
Microbiology (Reading, England) 2007;153(Pt 5):1445-54.
2007: Yu-Sing Tammy Chang; Jens Klockgether; Burkhard Tümmler
An intragenic deletion in pilQ leads to nonpiliation of a Pseudomonas aeruginosa strain isolated from cystic fibrosis lung.
FEMS microbiology letters 2007;270(2):201-6.
2007: Jens Klockgether; Dieco Würdemann; Oleg Reva; Lutz Wiehlmann; Burkhard Tümmler
Diversity of the abundant pKLC102/PAGI-2 family of genomic islands in Pseudomonas aeruginosa.
Journal of bacteriology 2007;189(6):2443-59.
2006: Alessandra Bragonzi; Lutz Wiehlmann; Jens Klockgether; Nina Cramer; Dieter Worlitzsch; Gerd Döring; Burkhard Tümmler
Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Microbiology (Reading, England) 2006;152(Pt 11):3261-9.
2006: Oleg Reva; Christian Weinel; Miryam Weinel; Kerstin Böhm; Diana Stjepandic; Jörg D Hoheisel; Burkhard Tümmler
Functional genomics of stress response in Pseudomonas putida KT2440.
Journal of bacteriology 2006;188(11):4079-92.
2006: Gregor Hagelueken; Thorsten M Adams; Lutz Wiehlmann; Ute Widow; Harald Kolmar; Burkhard Tümmler; Dirk W Heinz; Wolf-Dieter Schubert
The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7631-6.
2006: Burkhard Tümmler
Rescue of F508del CFTR: Commentary on "F508del CFTR with two altered RXR motifs escapes from ER quality control but its channel activity is thermally sensitive".
Biochimica et biophysica acta 2006;1758(5):563-4.
2006: Frauke Stanke; Manfred Ballmann; Burkhard Tümmler
Cystic fibrosis disease-specific centiles in 2000 and 2005.
American journal of respiratory and critical care medicine 2006;173(9):1047; author reply 1047.
2006: Andrea van Barneveld; Frauke Stanke; Manfred Ballmann; Hassan Y Naim; Burkhard Tümmler
Ex vivo biochemical analysis of CFTR in human rectal biopsies.
Biochimica et biophysica acta 2006;1762(4):393-7.
2006: Frauke Stanke; Tim Becker; Harry Cuppens; Vinod Kumar; Jean-Jacques Cassiman; Silke Jansen; Dragica Radojkovic; Benny Siebert; Jennifer Yarden; David W Ussery; Thomas F Wienker; Burkhard Tümmler
The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis.
Human genetics 2006;119(3):331-43.
2006: Frauke Stanke; Burkhard Tümmler; Tim Becker
Genetic modifiers in cystic fibrosis.
The New England journal of medicine 2006;354(1):88-90; author reply 88-90.
2006: Nikoletta Charizopoulou; Martina Wilke; Martina Dorsch; Alice Bot; Huub Jorna; Silke Jansen; Frauke Stanke; Hans J Hedrich; Hugo R de Jonge; Burkhard Tümmler
Spontaneous rescue from cystic fibrosis in a mouse model.
BMC genetics 2006;7():18.
2005: Kok-Fai Kong; Suriya R Jayawardena; Aimee Del Puerto; Lutz Wiehlmann; Ulrike Laabs; Burkhard Tümmler; Kalai Mathee
Characterization of poxB, a chromosomal-encoded Pseudomonas aeruginosa oxacillinase.
Gene 2005;358():82-92.
2005: Prabhakar Salunkhe; Catherine H M Smart; J Alun W Morgan; Stavroula Panagea; Martin J Walshaw; C Anthony Hart; Robert Geffers; Burkhard Tümmler; Craig Winstanley
A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance.
Journal of bacteriology 2005;187(14):4908-20.
2005: Burkhard Tümmler; Pierre Cornelis
Pyoverdine receptor: a case of positive Darwinian selection in Pseudomonas aeruginosa.
Journal of bacteriology 2005;187(10):3289-92.
2005: Antje Munder; Andrea Zelmer; Andreas Schmiedl; Kurt E J Dittmar; Manfred Rohde; Martina Dorsch; Klaus A Otto; Hans J Hedrich; Burkhard Tümmler; Siegfried Weiss; Thomas Tschernig
Murine pulmonary infection with Listeria monocytogenes: differential susceptibility of BALB/c, C57BL/6 and DBA/2 mice.
Microbes and infection / Institut Pasteur 2005;7(4):600-11.
2005: Mario Juhas; Leo Eberl; Burkhard Tümmler
Quorum sensing: the power of cooperation in the world of Pseudomonas.
Environmental microbiology 2005;7(4):459-71.
2005: Prabhakar Salunkhe; Tanja Töpfer; Jan Buer; Burkhard Tümmler
Genome-wide transcriptional profiling of the steady-state response of Pseudomonas aeruginosa to hydrogen peroxide.
Journal of bacteriology 2005;187(8):2565-72.
2005: Vincent T Lee; Roger S Smith; Burkhard Tümmler; Stephen Lory
Activities of Pseudomonas aeruginosa effectors secreted by the Type III secretion system in vitro and during infection.
Infection and immunity 2005;73(3):1695-705.
2005: Mario Juhas; Lutz Wiehlmann; Prabhakar Salunkhe; Jörg Lauber; Jan Buer; Burkhard Tümmler
GeneChip expression analysis of the VqsR regulon of Pseudomonas aeruginosa TB.
FEMS microbiology letters 2005;242(2):287-95.
2005: Oleg Reva; Burkhard Tümmler
Differentiation of regions with atypical oligonucleotide composition in bacterial genomes.
BMC bioinformatics 2005;6():251.
2004: Margit Ritzka; Frauke Stanke; Silke Jansen; Achim D Gruber; Larissa Pusch; Stefan Woelfl; Henk J Veeze; D J J Halley; Burkhard Tümmler
The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis.
Human genetics 2004;115(6):483-91.
2004: Senthil Selvan Saravanamuthu; Franz von Götz; Prabhakar Salunkhe; Rathinam Chozhavendan; Robert Geffers; Jan Buer; Burkhard Tümmler; Ivo Steinmetz
Evidence for polyadenylated mRNA in Pseudomonas aeruginosa.
Journal of bacteriology 2004;186(20):7015-8.
2004: Leo Eberl; Burkhard Tümmler
Pseudomonas aeruginosa and Burkholderia cepacia in cystic fibrosis: genome evolution, interactions and adaptation.
International journal of medical microbiology : IJMM 2004;294(2-3):123-31.
2004: Hugo R de Jonge; Manfred Ballmann; Henk J Veeze; Inez Bronsveld; Frauke Stanke; Burkhard Tümmler; Maarten Sinaasappel
Ex vivo CF diagnosis by intestinal current measurements (ICM) in small aperture, circulating Ussing chambers.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():159-63.
2004: Martin J Hug; Burkhard Tümmler
Intestinal current measurements to diagnose cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():157-8.
2004: Daniel Schüler; Isabelle Sermet-Gaudelus; Michael Wilschanski; Manfred Ballmann; Michèle Dechaux; Aleksander Edelman; Martin Hug; Teresinha Leal; Jean Lebacq; Patrick LEBECQUE; Gérard Lenoir; Frauke Stanke; Pierre Wallemacq; Burkhard Tümmler; Michael Knowles
Basic protocol for transepithelial nasal potential difference measurements.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():151-5.
2004: Burkhard Tümmler
In-vivo and ex-vivo functional assessment.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():149-50.
2004: Oleg Reva; Burkhard Tümmler
Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage patterns.
BMC bioinformatics 2004;5():90.
2004: Gracia Morales; Lutz Wiehlmann; Peter Gudowius; Christian van Delden; Burkhard Tümmler; José L Martínez; Fernando Rojo
Structure of Pseudomonas aeruginosa populations analyzed by single nucleotide polymorphism and pulsed-field gel electrophoresis genotyping.
Journal of bacteriology 2004;186(13):4228-37.
2004: Franz von Götz; Susanne Häussler; Doris Jordan; Senthil Selvan Saravanamuthu; Dirk Wehmhöner; André Strüssmann; Jörg Lauber; Ina Attree; Jan Buer; Burkhard Tümmler; Ivo Steinmetz
Expression analysis of a highly adherent and cytotoxic small colony variant of Pseudomonas aeruginosa isolated from a lung of a patient with cystic fibrosis.
Journal of bacteriology 2004;186(12):3837-47.
2004: Catalina Arevalo-Ferro; Julia Buschmann; Gerold Reil; Angelika Görg; Lutz Wiehlmann; Burkhard Tümmler; Leo Eberl; Kathrin Riedel
Proteome analysis of intraclonal diversity of two Pseudomonas aeruginosa TB clone isolates.
Proteomics 2004;4(5):1241-6.
2004: Nikoletta Charizopoulou; Silke Jansen; Martina Dorsch; Frauke Stanke; Julia R Dorin; Hans J Hedrich; Burkhard Tümmler
Instability of the insertional mutation in CftrTgH(neoim)Hgu cystic fibrosis mouse model.
BMC genetics 2004;5():6.
2004: Mario Juhas; Lutz Wiehlmann; Birgit Huber; Doris Jordan; Jörg Lauber; Prabhakar Salunkhe; Anna Silke Limpert; Franz von Götz; Ivo Steinmetz; Leo Eberl; Burkhard Tümmler
Global regulation of quorum sensing and virulence by VqsR in Pseudomonas aeruginosa.
Microbiology (Reading, England) 2004;150(Pt 4):831-41.
2004: Frauke Mekus; Burkhard Tümmler
Genes, environment, ion transport, and cystic fibrosis.
American journal of respiratory and critical care medicine 2004;169(6):770; author reply 770.
2004: Frauke Mekus; Burkhard Tümmler
Cystic fibrosis and NOS3.
American journal of respiratory and critical care medicine 2004;169(2):319-20; author reply 320.
2004: Jens Klockgether; Oleg Reva; Karen D Larbig; Burkhard Tümmler
Sequence analysis of the mobile genome island pKLC102 of Pseudomonas aeruginosa C.
Journal of bacteriology 2004;186(2):518-34.
2003: Dirk Wehmhöner; Susanne Häussler; Burkhard Tümmler; Lothar Jänsch; Florian Bredenbruch; Jürgen Wehland; Ivo Steinmetz
Inter- and intraclonal diversity of the Pseudomonas aeruginosa proteome manifests within the secretome.
Journal of bacteriology 2003;185(19):5807-14.
2003: Susanne Häussler; C Lehmann; C Breselge; Manfred Rohde; M Classen; Burkhard Tümmler; P Vandamme; Ivo Steinmetz
Fatal outcome of lung transplantation in cystic fibrosis patients due to small-colony variants of the Burkholderia cepacia complex.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2003;22(4):249-53.
2003: Susanne Häussler; Isabell Ziegler; Alexandra Löttel; Franz von Götz; Manfred Rohde; Dirk Wehmhöhner; Senthil Selvan Saravanamuthu; Burkhard Tümmler; Ivo Steinmetz
Highly adherent small-colony variants of Pseudomonas aeruginosa in cystic fibrosis lung infection.
Journal of medical microbiology 2003;52(Pt 4):295-301.
2003: Frauke Mekus; Ulrike Laabs; Henk J Veeze; Burkhard Tümmler
Genes in the vicinity of CFTR modulate the cystic fibrosis phenotype in highly concordant or discordant F508del homozygous sib pairs.
Human genetics 2003;112(1):1-11.
2002: Diana Stjepandić; Christian Weinel; Helmut Hilbert; Hean L Koo; Frank Diehl; Karen E Nelson; Burkhard Tümmler; Jörg D Hoheisel
The genome structure of Pseudomonas putida: high-resolution mapping and microarray analysis.
Environmental microbiology 2002;4(12):819-23.
2002: Christian Weinel; Karen E Nelson; Burkhard Tümmler
Global features of the Pseudomonas putida KT2440 genome sequence.
Environmental microbiology 2002;4(12):809-18.
2002: Karen D Larbig; Andreas Christmann; Andre Johann; Jens Klockgether; Thomas Hartsch; Rainer Merkl; Lutz Wiehlmann; Hans-Joachim Fritz; Burkhard Tümmler
Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone.
Journal of bacteriology 2002;184(23):6665-80.
2002: Antje Munder; S Krusch; Thomas Tschernig; Martina Dorsch; A Lührmann; Martijn van Griensven; Burkhard Tümmler; Siegfried Weiss; Hans J Hedrich
Pulmonary microbial infection in mice: comparison of different application methods and correlation of bacterial numbers and histopathology.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2002;54(2):127-33.
2002: Karen D Larbig; C Kiewitz; Burkhard Tümmler
Pathogenicity islands and PAI-like structures in Pseudomonas species.
Current topics in microbiology and immunology 2002;264(1):201-11.
2001: Inez Bronsveld; Frauke Mekus; Jan Bijman; Manfred Ballmann; Hugo R de Jonge; Ulrike Laabs; D J J Halley; H Ellemunter; G Mastella; S Thomas; Henk J Veeze; Burkhard Tümmler
Chloride conductance and genetic background modulate the cystic fibrosis phenotype of Delta F508 homozygous twins and siblings.
The Journal of clinical investigation 2001;108(11):1705-15.
2001: Christian Weinel; Burkhard Tümmler; Helmut Hilbert; Karen E Nelson; C Kiewitz
General method of rapid Smith/Birnstiel mapping adds for gap closure in shotgun microbial genome sequencing projects: application to Pseudomonas putida KT2440.
Nucleic acids research 2001;29(22):E110.
2001: Astrid Gotschlich; Birgit Huber; O Geisenberger; A Tögl; Anette Steidle; Kathrin Riedel; P Hill; Burkhard Tümmler; P Vandamme; Barry Middleton; M Camara; Paul Williams; Andrea Hardman; Leo Eberl
Synthesis of multiple N-acylhomoserine lactones is wide-spread among the members of the Burkholderia cepacia complex.
Systematic and applied microbiology 2001;24(1):1-14.
2001: Ulrich Baumann; J J Fischer; Peter Gudowius; M Lingner; S Herrmann; Burkhard Tümmler; Horst von der Hardt
Buccal adherence of Pseudomonas aeruginosa in patients with cystic fibrosis under long-term therapy with azithromycin.
Infection 2001;29(1):7-11.
2000: Frauke Mekus; Manfred Ballmann; Inez Bronsveld; Jan Bijman; Henk J Veeze; Burkhard Tümmler
Categories of deltaF508 homozygous cystic fibrosis twin and sibling pairs with distinct phenotypic characteristics.
Twin research : the official journal of the International Society for Twin Studies 2000;3(4):277-93.
2000: C Kiewitz; Karen D Larbig; Jens Klockgether; Christian Weinel; Burkhard Tümmler
Monitoring genome evolution ex vivo: reversible chromosomal integration of a 106 kb plasmid at two tRNA(Lys) gene loci in sequential Pseudomonas aeruginosa airway isolates.
Microbiology (Reading, England) 2000;146 ( Pt 10)():2365-73.
2000: Inez Bronsveld; Frauke Mekus; Jan Bijman; Manfred Ballmann; J Greipel; J Hundrieser; D J J Halley; Ulrike Laabs; R Busche; Hugo R de Jonge; Burkhard Tümmler; Henk J Veeze
Residual chloride secretion in intestinal tissue of deltaF508 homozygous twins and siblings with cystic fibrosis. The European CF Twin and Sibling Study Consortium.
Gastroenterology 2000;119(1):32-40.
2000: A Claass; M Sommer; H de Jonge; N Kälin; Burkhard Tümmler
Applicability of different antibodies for immunohistochemical localization of CFTR in sweat glands from healthy controls and from patients with cystic fibrosis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(6):831-7.
2000: C Kiewitz; Burkhard Tümmler
Sequence diversity of Pseudomonas aeruginosa: impact on population structure and genome evolution.
Journal of bacteriology 2000;182(11):3125-35.
2000: Sylvain Brisse; Cees M Verduin; D Milatovic; Ad C Fluit; Jan Verhoef; S Laevens; P Vandamme; Burkhard Tümmler; Henri A Verbrugh; Alex Van Belkum
Distinguishing species of the Burkholderia cepacia complex and Burkholderia gladioli by automated ribotyping.
Journal of clinical microbiology 2000;38(5):1876-84.
2000: O Geisenberger; Michael Givskov; Kathrin Riedel; Niels Høiby; Burkhard Tümmler; Leo Eberl
Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis.
FEMS microbiology letters 2000;184(2):273-8.
2000: Thilo Dörk; M Macek; Frauke Mekus; Burkhard Tümmler; J Tzountzouris; Teresa Casals; A Krebsová; M Koudová; I Sakmaryová; Milan Macek Jr.; Vera Vávrová; Daniela Zemková; E Ginter; N V Petrova; TE Ivaschenko; V Baranov; M Witt; Andrzej Pogorzelski; Jerzy Bal; C Zékanowsky; K Wagner; Manfred Stuhrmann; I Bauer; H H Seydewitz; T Neumann; Sibylle Jakubiczka
Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: a cystic fibrosis mutation of Slavic origin common in Central and East Europe.
Human genetics 2000;106(3):259-68.
1999: Susanne Häussler; Burkhard Tümmler; Hartmut Weissbrodt; Manfred Rohde; Ivo Steinmetz
Small-colony variants of Pseudomonas aeruginosa in cystic fibrosis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999;29(3):621-5.
1999: Burkhard Tümmler; C Kiewitz
Cystic fibrosis: an inherited susceptibility to bacterial respiratory infections.
Molecular medicine today 1999;5(8):351-8.
1999: Cindy van Pelt; Cees M Verduin; W H F Goessens; Margreet C Vos; Burkhard Tümmler; C Segonds; F Reubsaet; Henri A Verbrugh; Alex Van Belkum
Identification of Burkholderia spp. in the clinical microbiology laboratory: comparison of conventional and molecular methods.
Journal of clinical microbiology 1999;37(7):2158-64.
1999: N Kälin; A Claass; M Sommer; E Puchelle; Burkhard Tümmler
DeltaF508 CFTR protein expression in tissues from patients with cystic fibrosis.
The Journal of clinical investigation 1999;103(10):1379-89.
1999: Inez Bronsveld; Jan Bijman; Frauke Mekus; Manfred Ballmann; Henk J Veeze; Burkhard Tümmler
Clinical presentation of exclusive cystic fibrosis lung disease.
Thorax 1999;54(3):278-81.
1998: Frauke Mekus; Manfred Ballmann; Inez Bronsveld; Thilo Dörk; Jan Bijman; Burkhard Tümmler; Henk J Veeze
Cystic-fibrosis-like disease unrelated to the cystic fibrosis transmembrane conductance regulator.
Human genetics 1998;102(5):582-6.
1998: C Spangenberg; T C Montie; Burkhard Tümmler
Structural and functional implications of sequence diversity of Pseudomonas aeruginosa genes oriC, ampC and fliC.
Electrophoresis 1998;19(4):545-50.
1998: KD Schmidt; T Schmidt-Rose; U Römling; Burkhard Tümmler
Differential genome analysis of bacteria by genomic subtractive hybridization and pulsed field gel electrophoresis.
Electrophoresis 1998;19(4):509-14.
1998: T Heuer; C Bürger; Burkhard Tümmler
Smith/Birnstiel mapping of genome rearrangements in Pseudomonas aeruginosa.
Electrophoresis 1998;19(4):495-9.
1998: T Heuer; C Bürger; G Maass; Burkhard Tümmler
Cloning of prokaryotic genomes in yeast artificial chromosomes: application to the population genetics of Pseudomonas aeruginosa.
Electrophoresis 1998;19(4):486-94.
1997: S Breitenstein; S Walter; J Bosshammer; U Römling; Burkhard Tümmler
Direct sputum analysis of Pseudomonas aeruginosa macrorestriction fragment genotypes in patients with cystic fibrosis.
Medical microbiology and immunology 1997;186(2-3):93-9.
1997: U Römling; KD Schmidt; Burkhard Tümmler
Large genome rearrangements discovered by the detailed analysis of 21 Pseudomonas aeruginosa clone C isolates found in environment and disease habitats.
Journal of molecular biology 1997;271(3):386-404.
1997: Wolfgang Bernhard; J Y Wang; Thomas Tschernig; Burkhard Tümmler; Hans J Hedrich; Horst von der Hardt
Lung surfactant in a cystic fibrosis animal model: increased alveolar phospholipid pool size without altered composition and surface tension function in cftrm1HGU/m1HGU mice.
Thorax 1997;52(8):723-30.
1997: C Spangenberg; R Fislage; U Römling; Burkhard Tümmler
Disrespectful type IV pilins.
Molecular microbiology 1997;25(1):203-4.
1997: U Römling; KD Schmidt; Burkhard Tümmler
Large chromosomal inversions occur in Pseudomonas aeruginosa clone C strains isolated from cystic fibrosis patients.
FEMS microbiology letters 1997;150(1):149-56.
1997: Siegbert Walter; Peter Gudowius; J Bosshammer; U Römling; Hartmut Weissbrodt; W Schürmann; Horst von der Hardt; Burkhard Tümmler
Epidemiology of chronic Pseudomonas aeruginosa infections in the airways of lung transplant recipients with cystic fibrosis.
Thorax 1997;52(4):318-21.
1997: Burkhard Tümmler; J Bosshammer; S Breitenstein; I Brockhausen; Peter Gudowius; C Herrmann; S Herrmann; T Heuer; P Kubesch; Frauke Mekus; U Römling; KD Schmidt; C Spangenberg; Siegbert Walter
Infections with Pseudomonas aeruginosa in patients with cystic fibrosis.
Behring Institute Mitteilungen 1997;(98):249-55.
1996: A Demmer; T Dunn; T Hoof; P Kubesch; Burkhard Tümmler
Competitive inhibition of photoaffinity labelling of P-glycoprotein by anticancer drugs and modulators including S9788.
European journal of pharmacology 1996;315(3):339-43.
1996: C Spangenberg; T Heuer; C Bürger; Burkhard Tümmler
Genetic diversity of flagellins of Pseudomonas aeruginosa.
FEBS letters 1996;396(2-3):213-7.
1996: Burkhard Tümmler; T Storrs; V Dziadek; Thilo Dörk; Thomas Meitinger; Astrid Golla; R M Bertele-Harms; H K Harms; E Schröder; A Claass; J Rutjes; Reinhard Schneppenheim; I Bauer; K Breuel; Manfred Stuhrmann; Jörg Schmidtke; M Lindner; Antonin Eigel; Jürgen Horst; R Kaiser; M J Lentze; K Schmidt; H von der Hardt; Xavier Estivill
Geographic distribution and origin of CFTR mutations in Germany.
Human genetics 1996;97(6):727-31.
1996: N Morral; Thilo Dörk; R Llevadot; V Dziadek; Bernard Mercier; Claude Férec; Bruno Costes; Emmanuelle Girodon; Julian Zielenski; L C Tsui; Burkhard Tümmler; Xavier Estivill
Haplotype analysis of 94 cystic fibrosis mutations with seven polymorphic CFTR DNA markers.
Human mutation 1996;8(2):149-59.
1996: KD Schmidt; Burkhard Tümmler; U Römling
Comparative genome mapping of Pseudomonas aeruginosa PAO with P. aeruginosa C, which belongs to a major clone in cystic fibrosis patients and aquatic habitats.
Journal of bacteriology 1996;178(1):85-93.
1995: J Bosshammer; B Fiedler; Peter Gudowius; H von der Hardt; U Römling; Burkhard Tümmler
Comparative hygienic surveillance of contamination with pseudomonads in a cystic fibrosis ward over a 4-year period.
The Journal of hospital infection 1995;31(4):261-74.
1995: Frauke Mekus; Thilo Dörk; T Deufel; N Morral; Burkhard Tümmler
Analysis of microsatellites by direct blotting electrophoresis and chemiluminescence detection.
Electrophoresis 1995;16(10):1886-8.
1995: Florence Dupuit; N Kälin; S Brézillon; Jocelyne Hinnrasky; Burkhard Tümmler; Edith Puchelle
CFTR and differentiation markers expression in non-CF and delta F 508 homozygous CF nasal epithelium.
The Journal of clinical investigation 1995;96(3):1601-11.
1995: T Brandt; S Breitenstein; Horst von der Hardt; Burkhard Tümmler
DNA concentration and length in sputum of patients with cystic fibrosis during inhalation with recombinant human DNase.
Thorax 1995;50(8):880-2.
1995: U Römling; J Greipel; Burkhard Tümmler
Gradient of genomic diversity in the Pseudomonas aeruginosa chromosome.
Molecular microbiology 1995;17(2):323-32.
1995: P D Rodley; U Römling; Burkhard Tümmler
A physical genome map of the Burkholderia cepacia type strain.
Molecular microbiology 1995;17(1):57-67.
1995: C Spangenberg; R Fislage; W Sierralta; Burkhard Tümmler; U Römling
Comparison of type IV-pilin genes of Pseudomonas aeruginosa of various habitats has uncovered a novel unusual sequence.
FEMS microbiology letters 1995;127(1-2):158.
1995: S Breitenstein; Burkhard Tümmler; U Römling
Pulsed field gel electrophoresis of bacterial DNA isolated directly from patients' sputa.
Nucleic acids research 1995;23(4):722-3.
1995: U Römling; R Fislage; Burkhard Tümmler
[Theory and practice of macrorestriction analysis for the clonal analysis of pathogens].
Immunität und Infektion 1995;23(1):4-8.
1995: S Brezillon; Florence Dupuit; Jocelyne Hinnrasky; V Marchand; N Kälin; Burkhard Tümmler; Edith Puchelle
Decreased expression of the CFTR protein in remodeled human nasal epithelium from non-cystic fibrosis patients.
Laboratory investigation; a journal of technical methods and pathology 1995;72(2):191-200.
1995: C Spangenberg; R Fislage; W Sierralta; Burkhard Tümmler; U Römling
Comparison of type IV-pilin genes of Pseudomonas aeruginosa of various habitats has uncovered a novel unusual sequence.
FEMS microbiology letters 1995;125(2-3):265-73.
1995: K Will; Thilo Dörk; Manfred Stuhrmann; H von der Hardt; Helmut Ellemunter; Burkhard Tümmler; Jörg Schmidtke
Transcript analysis of CFTR nonsense mutations in lymphocytes and nasal epithelial cells from cystic fibrosis patients.
Human mutation 1995;5(3):210-20.
1994: U Römling; B Fiedler; J Bosshammer; D Grothues; J Greipel; H von der Hardt; Burkhard Tümmler
Epidemiology of chronic Pseudomonas aeruginosa infections in cystic fibrosis.
The Journal of infectious diseases 1994;170(6):1616-21.
1994: T Hoof; A Demmer; M R Hadam; John R Riordan; Burkhard Tümmler
Cystic fibrosis-type mutational analysis in the ATP-binding cassette transporter signature of human P-glycoprotein MDR1.
The Journal of biological chemistry 1994;269(32):20575-83.
1994: K Will; Thilo Dörk; Manfred Stuhrmann; Thomas Meitinger; R Bertele-Harms; Burkhard Tümmler; Jörg Schmidtke
A novel exon in the cystic fibrosis transmembrane conductance regulator gene activated by the nonsense mutation E92X in airway epithelial cells of patients with cystic fibrosis.
The Journal of clinical investigation 1994;93(4):1852-9.
1994: Thilo Dörk; K Will; K Grade; M Krawczak; Burkhard Tümmler
A 32-bp deletion (2991del32) in the cystic fibrosis gene associated with CFTR mRNA reduction.
Human mutation 1994;4(1):65-70.
1994: Thilo Dörk; R Fislage; T Neumann; B Wulf; Burkhard Tümmler
Exon 9 of the CFTR gene: splice site haplotypes and cystic fibrosis mutations.
Human genetics 1994;93(1):67-73.
1993: Thilo Dörk; K Will; A Demmer; Burkhard Tümmler
A donor splice mutation (405 + 1 G-->A) in cystic fibrosis associated with exon skipping in epithelial CFTR mRNA.
Human molecular genetics 1993;2(11):1965-6.
1993: Thilo Dörk; R Fislage; U Rappen; Burkhard Tümmler
Severe splice site mutation preceding exon 9 of the CFTR gene.
Human molecular genetics 1993;2(8):1313-4.
1993: Burkhard Tümmler; Thilo Dörk; P Kubesch; R Fislage; N Kälin; T Neumann; U Wulbrand; B Wulf; G Steinkamp; H von der Hardt
Cystic fibrosis: the impact of analytical technology for genotype-phenotype studies.
Clinica chimica acta; international journal of clinical chemistry 1993;217(1):23-8.
1993: T Hoof; A Demmer; Uwe Christians; Burkhard Tümmler
Reversal of multidrug resistance in Chinese hamster ovary cells by the immunosuppressive agent rapamycin.
European journal of pharmacology 1993;246(1):53-8.
1993: U Römling; Burkhard Tümmler
Comparative mapping of the Pseudomonas aeruginosa PAO genome with rare-cutter linking clones or two-dimensional pulsed-field gel electrophoresis protocols.
Electrophoresis 1993;14(4):283-9.
1993: Thilo Dörk; U Wulbrand; Burkhard Tümmler
Four novel cystic fibrosis mutations in splice junction sequences affecting the CFTR nucleotide binding folds.
Genomics 1993;15(3):688-91.
1993: P Kubesch; Thilo Dörk; U Wulbrand; N Kälin; T Neumann; B Wulf; H Geerlings; Hartmut Weissbrodt; H von der Hardt; Burkhard Tümmler
Genetic determinants of airways' colonisation with Pseudomonas aeruginosa in cystic fibrosis.
Lancet 1993;341(8839):189-93.
1993: Joan M Boggs; Burkhard Tümmler
Interdigitated gel phase bilayers formed by unsaturated synthetic and bacterial glycerolipids in the presence of polymyxin B and glycerol.
Biochimica et biophysica acta 1993;1145(1):42-50.
1993: Thilo Dörk; R Fislage; Burkhard Tümmler
Complex mutation 4114 ATA-->TT in exon 22 of the cystic fibrosis gene CFTR.
Human mutation 1993;2(6):489-91.
1992: Thilo Dörk; N Kälin; Manfred Stuhrmann; Jörg Schmidtke; Burkhard Tümmler
A termination mutation (2143delT) in the CFTR gene of German cystic fibrosis patients.
Human genetics 1992;90(3):279-84.
1992: T Hoof; R Fislage; Burkhard Tümmler
Primary sequence of the human ribosomal protein L37a.
Nucleic acids research 1992;20(20):5475.
1992: N Kälin; Thilo Dörk; D Bozon; Burkhard Tümmler
A novel frame-shift mutation in exon 4 of the cystic fibrosis gene (435insA) demonstrates the ambiguity of restriction analysis for mutation screening.
Human molecular genetics 1992;1(7):545-6.
1992: U Römling; Burkhard Tümmler
A PacI/SwaI map of the Pseudomonas aeruginosa PAO chromosome.
Electrophoresis 1992;13(9-10):649-51.
1992: U Römling; D Grothues; U Koopmann; B Jahnke; J Greipel; Burkhard Tümmler
Pulsed-field gel electrophoresis analysis of a Pseudomonas aeruginosa pathovar.
Electrophoresis 1992;13(9-10):646-8.
1992: U Römling; D Grothues; T Heuer; Burkhard Tümmler
Physical genome analysis of bacteria.
Electrophoresis 1992;13(9-10):626-31.
1992: S Bremer; T Hoof; M Wilke; Roger Busche; Bob J Scholte; John R Riordan; G Maass; Burkhard Tümmler
Quantitative expression patterns of multidrug-resistance P-glycoprotein (MDR1) and differentially spliced cystic-fibrosis transmembrane-conductance regulator mRNA transcripts in human epithelia.
European journal of biochemistry / FEBS 1992;206(1):137-49.
1992: Thilo Dörk; U Wulbrand; G Steinkamp; Burkhard Tümmler
Mild course of cystic fibrosis associated with heterozygosity for infrequent mutations in the first nucleotide-binding fold of CFTR.
Acta paediatrica (Oslo, Norway : 1992) 1992;81(1):82-3.
1992: N Kälin; Thilo Dörk; Burkhard Tümmler
A cystic fibrosis allele encoding missense mutations in both nucleotide binding folds of the cystic fibrosis transmembrane conductance regulator.
Human mutation 1992;1(3):204-10.
1991: D Grothues; Burkhard Tümmler
New approaches in genome analysis by pulsed-field gel electrophoresis: application to the analysis of Pseudomonas species.
Molecular microbiology 1991;5(11):2763-76.
1991: T Grundmann; Joachim Freihorst; P Kubesch; Burkhard Tümmler; H von der Hardt
[Local immunization against P. aeruginosa with an outer-membrane-protein vaccine].
Pneumologie (Stuttgart, Germany) 1991;45(11):924-7.
1991: Thilo Dörk; U Wulbrand; T Richter; T Neumann; Heiner Wolfes; B Wulf; G Maass; Burkhard Tümmler
Cystic fibrosis with three mutations in the cystic fibrosis transmembrane conductance regulator gene.
Human genetics 1991;87(4):441-6.
1991: B Kroll; S Bremer; Burkhard Tümmler; Gabor Kottra; Eberhard Frömter
Sodium dependence of the epithelial sodium conductance expressed in Xenopus laevis oocytes.
Pflügers Archiv : European journal of physiology 1991;419(1):101-7.
1991: T Hoof; John R Riordan; Burkhard Tümmler
Quantitation of mRNA by the kinetic polymerase chain reaction assay: a tool for monitoring P-glycoprotein gene expression.
Analytical biochemistry 1991;196(1):161-9.
1991: U Römling; Burkhard Tümmler
The impact of two-dimensional pulsed-field gel electrophoresis techniques for the consistent and complete mapping of bacterial genomes: refined physical map of Pseudomonas aeruginosa PAO.
Nucleic acids research 1991;19(12):3199-206.
1991: Burkhard Tümmler; U Koopmann; D Grothues; Hartmut Weissbrodt; G Steinkamp; H von der Hardt
Nosocomial acquisition of Pseudomonas aeruginosa by cystic fibrosis patients.
Journal of clinical microbiology 1991;29(6):1265-7.
1991: Thilo Dörk; U Wulbrand; Burkhard Tümmler
A HinfI polymorphism in the cystic fibrosis gene CFTR.
Nucleic acids research 1991;19(9):2517.
1991: U Wulbrand; Thilo Dörk; Burkhard Tümmler; M Krawczak
Genetic determinants in cystic fibrosis.
Lancet 1991;337(8741):623.
1991: U Römling; D Grothues; Burkhard Tümmler
Whole DNA genome typing.
Antibiotics and chemotherapy 1991;44():1-7.
1990: Joachim Hundrieser; S Bremer; Frank Peinemann; Manfred Stuhrmann; N Hoffknecht; B Wulf; Jörg Schmidtke; Jochen Reiss; G Maass; Burkhard Tümmler
Frequency of the F508 deletion in the CFTR gene in Turkish cystic fibrosis patients.
Human genetics 1990;85(4):409-10.
1990: D F Cano-Gauci; Roger Busche; Burkhard Tümmler; John R Riordan
Fast kinetic analysis of drug transport in multidrug resistant cells using a pulsed quench-flow apparatus.
Biochemical and biophysical research communications 1990;167(1):48-53.
1990: Burkhard Tümmler; A Aschendorff; T Darnedde; K Fryburg; G Maass; Joachim Hundrieser
Marker haplotype association with growth in German cystic fibrosis patients.
Human genetics 1990;84(3):267-73.
1989: U Römling; D Grothues; Wilfried Bautsch; Burkhard Tümmler
A physical genome map of Pseudomonas aeruginosa PAO.
The EMBO journal 1989;8(13):4081-9.
1989: Joan M Boggs; H Y Wang; Godha Rangaraj; Burkhard Tümmler
Interdigitation of phosphatidylcholine and phosphatidylethanolamine mixed with complexes of acidic lipids and polymyxin B or polymyxin B nonapeptide.
Biochimica et biophysica acta 1989;985(2):199-210.
1989: H Y Wang; Burkhard Tümmler; Joan M Boggs
Use of spin labels to determine the percentage of interdigitated lipid in complexes with polymyxin B and polymyxin B nonapeptide.
Biochimica et biophysica acta 1989;985(2):182-98.
1989: B Kroll; Wilfried Bautsch; S Bremer; M Wilke; Burkhard Tümmler; Eberhard Frömter
Selective expression of an amiloride-inhibitable Na+ conductance from mRNA of respiratory epithelium in Xenopus laevis oocytes.
The American journal of physiology 1989;257(4 Pt 1):L284-8.
1989: Roger Busche; Burkhard Tümmler; D F Cano-Gauci; John R Riordan
Equilibrium, kinetic and photoaffinity labeling studies of daunomycin binding to P-glycoprotein-containing membranes of multidrug-resistant Chinese hamster ovary cells.
European journal of biochemistry / FEBS 1989;183(1):189-97.
1989: Roger Busche; Burkhard Tümmler; John R Riordan; D F Cano-Gauci
Preparation and utility of a radioiodinated analogue of daunomycin in the study of multidrug resistance.
Molecular pharmacology 1989;35(4):414-21.
1989: G Steinkamp; Burkhard Tümmler; Monika Gappa; A Albus; J Potel; Gerd Döring; H von der Hardt
Long-term tobramycin aerosol therapy in cystic fibrosis.
Pediatric pulmonology 1989;6(2):91-8.
1988: P Kubesch; B U von Specht; Burkhard Tümmler
Immune response in cystic fibrosis to outer membrane proteins of Pseudomonas aeruginosa.
Zentralblatt für Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology 1988;269(3):395-410.
1988: D Grothues; U Koopmann; H von der Hardt; Burkhard Tümmler
Genome fingerprinting of Pseudomonas aeruginosa indicates colonization of cystic fibrosis siblings with closely related strains.
Journal of clinical microbiology 1988;26(10):1973-7.
1988: T Darnedde; Burkhard Tümmler; E Schlesinger; H von der Hardt
DNA typing of a cystic fibrosis family with borderline sweat tests.
Acta paediatrica Scandinavica 1988;77(3):448-9.
1988: Monika Gappa; G Steinkamp; Burkhard Tümmler; H von der Hardt
Long-term tobramycin aerosol therapy of chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis.
Scandinavian journal of gastroenterology. Supplement 1988;143():74-6.
1988: P Kubesch; M Lingner; D Grothues; M Wehsling; Burkhard Tümmler
Strategies of Pseudomonas aeruginosa to colonize and to persist in the cystic fibrosis lung.
Scandinavian journal of gastroenterology. Supplement 1988;143():77-80.
1987: P Kubesch; M Wehsling; Burkhard Tümmler
Membrane permeability of Pseudomonas aeruginosa to 4-quinolones.
Zentralblatt für Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology 1987;265(1-2):197-202.