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Ching-Hsuan Tung

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Law Benedict; Tung Ching-Hsuan
Proteolysis: a biological process adapted in drug delivery, therapy, and imaging.
Kozloff Kenneth M; Quinti Luisa; Patntirapong Somying; Hauschka Peter V; Tung Ching-Hsuan; Weissleder Ralph; Mahmood Umar
Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.
Nahrendorf Matthias; Aikawa Elena; Figueiredo Jose-Luiz; Stangenberg Lars; van den Borne Susanne W; Blankesteijn W Matthijs; Sosnovik David E; Jaffer Farouc A; Tung Ching-Hsuan; Weissleder Ralph
Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction.

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2009: Law Benedict; Tung Ching-Hsuan
Proteolysis: a biological process adapted in drug delivery, therapy, and imaging.
Bioconjugate chemistry 2009;20(9):1683-95.
2009: Kozloff Kenneth M; Quinti Luisa; Patntirapong Somying; Hauschka Peter V; Tung Ching-Hsuan; Weissleder Ralph; Mahmood Umar
Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.
Bone 2009;44(2):190-8.
2008: Nahrendorf Matthias; Aikawa Elena; Figueiredo Jose-Luiz; Stangenberg Lars; van den Borne Susanne W; Blankesteijn W Matthijs; Sosnovik David E; Jaffer Farouc A; Tung Ching-Hsuan; Weissleder Ralph
Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction.
European heart journal 2008;29(4):445-54.
2008: Law Benedict; Tung Ching-Hsuan
Structural modification of protease inducible preprogrammed nanofiber precursor.
Biomacromolecules 2008;9(2):421-5.
2008: Gounaris Elias; Tung Ching H; Restaino Clifford; Maehr René; Kohler Rainer; Joyce Johanna A; Ploegh Hidde L; Barrett Terrence A; Weissleder Ralph; Khazaie Khashayarsha
Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth.
PloS one 2008;3(8):e2916.
2007: Law Benedict; Weissleder Ralph; Tung Ching-Hsuan
Protease-sensitive fluorescent nanofibers.
Bioconjugate chemistry 2007;18(6):1701-4.
2007: Kim Youngmi; Choi Yongdoo; Weissleder Ralph; Tung Ching-Hsuan
Membrane permeable esterase-activated fluorescent imaging probe.
Bioorganic & medicinal chemistry letters 2007;17(18):5054-7.
2007: Lai Koon Siew; Ho Nan-Hui; Cheng Jonathan D; Tung Ching-Hsuan
Selective fluorescence probes for dipeptidyl peptidase activity-fibroblast activation protein and dipeptidyl peptidase IV.
Bioconjugate chemistry 2007;18(4):1246-50.
2007: Kim Youngmi; Hilderbrand Scott A; Weissleder Ralph; Tung Ching-Hsuan
Sugar sensing based on induced pH changes.
Chemical communications (Cambridge, England) 2007;(22):2299-301.
2007: Jaffer Farouc A; Kim Dong-Eog; Quinti Luisa; Tung Ching-Hsuan; Aikawa Elena; Pande Ashvin N; Kohler Rainer H; Shi Guo-Ping; Libby Peter; Weissleder Ralph
Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor.
Circulation 2007;115(17):2292-8.
2007: Ho Nan-Hui; Weissleder Ralph; Tung Ching-Hsuan
A self-immolative reporter for beta-galactosidase sensing.
Chembiochem : a European journal of chemical biology 2007;8(5):560-6.
2007: Choi Yongdoo; Ho Nan-Hui; Tung Ching-Hsuan
Sensing phosphatase activity by using gold nanoparticles.
Angewandte Chemie (International ed. in English) 2007;46(5):707-9.
2006: Law Benedict; Quinti Luisa; Choi Yongdoo; Weissleder Ralph; Tung Ching-Hsuan
A mitochondrial targeted fusion peptide exhibits remarkable cytotoxicity.
Molecular cancer therapeutics 2006;5(8):1944-9.
2006: Choi Yongdoo; Weissleder Ralph; Tung Ching-Hsuan
Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate.
ChemMedChem 2006;1(7):698-701.
2006: Galande Amit K; Hilderbrand Scott A; Weissleder Ralph; Tung Ching-Hsuan
Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core.
Journal of medicinal chemistry 2006;49(15):4715-20.
2006: Choi Yongdoo; Weissleder Ralph; Tung Ching-Hsuan
Selective antitumor effect of novel protease-mediated photodynamic agent.
Cancer research 2006;66(14):7225-9.
2006: Deguchi Jun-o; Aikawa Masanori; Tung Ching-Hsuan; Aikawa Elena; Kim Dong-Eog; Ntziachristos Vasilis; Weissleder Ralph; Libby Peter
Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo.
Circulation 2006;114(1):55-62.
2006: Hsiao Jong-Kai; Law Benedict; Weissleder Ralph; Tung Ching-Hsuan
In-vivo imaging of tumor associated urokinase-type plasminogen activator activity.
Journal of biomedical optics 2006;11(3):34013.
2006: Ho Nan-Hui; Weissleder Ralph; Tung Ching-Hsuan
Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate.
Bioorganic & medicinal chemistry letters 2006;16(10):2599-602.
2006: Choi Yongdoo; McCarthy Jason R; Weissleder Ralph; Tung Ching-Hsuan
Conjugation of a photosensitizer to an oligoarginine-based cell-penetrating peptide increases the efficacy of photodynamic therapy.
ChemMedChem 2006;1(4):458-63.
2006: Law Benedict; Weissleder Ralph; Tung Ching-Hsuan
Peptide-based biomaterials for protease-enhanced drug delivery.
Biomacromolecules 2006;7(4):1261-5.
2006: Galande Amit K; Weissleder Ralph; Tung Ching-Hsuan
Fluorescence probe with a pH-sensitive trigger.
Bioconjugate chemistry 2006;17(2):255-7.
2006: Quinti Luisa; Weissleder Ralph; Tung Ching-Hsuan
A fluorescent nanosensor for apoptotic cells.
Nano letters 2006;6(3):488-90.
2006: Nahrendorf Matthias; Hu Kai; Frantz Stefan; Jaffer Farouc A; Tung Ching-Hsuan; Hiller Karl-Heinz; Voll Sabine; Nordbeck Peter; Sosnovik David; Gattenlöhner Stefan; Novikov Mikhail; Dickneite Gerhard; Reed Guy L; Jakob Peter; Rosenzweig Anthony; Bauer Wolfgang R; Weissleder Ralph; Ertl Georg
Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction.
Circulation 2006;113(9):1196-202.
2006: Bringer Marie-Agnès; Glasser Anne-Lise; Tung Ching-Hsuan; Méresse Stéphane; Darfeuille-Michaud Arlette
The Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages.
Cellular microbiology 2006;8(3):471-84.
2006: Zhang Yu-Min; Tung Ching-Hsuan; He Jiang; Liu Ning; Yanachkov Ivan; Liu Guozheng; Rusckowski Mary; Vanderheyden Jean-Luc
Construction of a novel chimera consisting of a chelator-containing Tat peptide conjugated to a morpholino antisense oligomer for technetium-99m labeling and accelerating cellular kinetics.
Nuclear medicine and biology 2006;33(2):263-9.
2005: Lamfers Martine L M; Gianni Davide; Tung Ching-Hsuan; Idema Sander; Schagen Frederik H E; Carette Jan E; Quax Paul H A; Van Beusechem Victor W; Vandertop W Peter; Dirven Clemens M F; Chiocca E Antonio; Gerritsen Winald R
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Cancer research 2005;65(20):9398-405.
2005: Hilderbrand Scott A; Kelly Kimberley A; Weissleder Ralph; Tung Ching-Hsuan
Monofunctional near-infrared fluorochromes for imaging applications.
Bioconjugate chemistry 2005;16(5):1275-81.
2005: Law Benedict; Weissleder Ralph; Tung Ching-Hsuan
Mechanism-based fluorescent reporter for protein kinase A detection.
Chembiochem : a European journal of chemical biology 2005;6(8):1361-7.
2005: Shah Khalid; Tung Ching-Hsuan; Breakefield Xandra O; Weissleder Ralph
In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(6):926-31.
2005: Chen Jiqiu; Tung Ching-Hsuan; Allport Jennifer R; Chen Si; Weissleder Ralph; Huang Paul L
Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction.
Circulation 2005;111(14):1800-5.
2005: Galande Amit K; Weissleder Ralph; Tung Ching-Hsuan
An effective method of on-resin disulfide bond formation in peptides.
Journal of combinatorial chemistry 2005;7(2):174-7.
2005: Law Benedict; Hsiao Jong-Kai; Bugge Thomas H; Weissleder Ralph; Tung Ching-Hsuan
Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples.
Analytical biochemistry 2005;338(1):151-8.
2005: Kim Dong-Eog; Schellingerhout Dawid; Jaffer Farouc A; Weissleder Ralph; Tung Ching-Hsuan
Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(2):226-33.
2005: Chen Wei-Tsung; Khazaie Khashayarsha; Zhang Guoying; Weissleder Ralph; Tung Ching-Hsuan
Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe.
Molecular imaging : official journal of the Society for Molecular Imaging 2005;4(1):67-74.
2005: Tung Ching-Hsuan; Quinti Luisa; Jaffer Farouc A; Weissleder Ralph
A branched fluorescent peptide probe for imaging of activated platelets.
Molecular pharmaceutics 2005;2(1):92-5.
2005: Chen Wei-Tsung; Mahmood Umar; Weissleder Ralph; Tung Ching-Hsuan
Arthritis imaging using a near-infrared fluorescence folate-targeted probe.
Arthritis research & therapy 2005;7(2):R310-7.
2004: Pham Wellington; Choi Yongdoo; Weissleder Ralph; Tung Ching-Hsuan
Developing a peptide-based near-infrared molecular probe for protease sensing.
Bioconjugate chemistry 2004;15(6):1403-7.
2004: Wunder Andreas; Tung Ching-Hsuan; Müller-Ladner Ulf; Weissleder Ralph; Mahmood Umar
In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.
Arthritis and rheumatism 2004;50(8):2459-65.
2004: Pham Wellington; Kircher Moritz F; Weissleder Ralph; Tung Ching-Hsuan
Enhancing membrane permeability by fatty acylation of oligoarginine peptides.
Chembiochem : a European journal of chemical biology 2004;5(8):1148-51.
2004: Chen Wei-Tsung; Tung Ching-Hsuan; Weissleder Ralph
Imaging reactive oxygen species in arthritis.
Molecular imaging : official journal of the Society for Molecular Imaging 2004;3(3):159-62.
2004: Jaffer Farouc A; Tung Ching-Hsuan; Wykrzykowska Joanna J; Ho Nan-Hui; Houng Aiilyan K; Reed Guy L; Weissleder Ralph
Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi.
Circulation 2004;110(2):170-6.
2004: Shah Khalid; Tung Ching-Hsuan; Yang Katherine; Weissleder Ralph; Breakefield Xandra O
Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy.
Cancer research 2004;64(9):3236-42.
2004: Messerli Shanta M; Prabhakar Shilpa; Tang Yi; Shah Khalid; Cortes Maria L; Murthy Vidya; Weissleder Ralph; Breakefield Xandra O; Tung Ching-Hsuan
A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe.
Neoplasia (New York, N.Y.) 2004;6(2):95-105.
2004: Tung Ching-Hsuan; Zeng Qing; Shah Khalid; Kim Dong-Eog; Schellingerhout Dawid; Weissleder Ralph
In vivo imaging of beta-galactosidase activity using far red fluorescent switch.
Cancer research 2004;64(5):1579-83.
2004: Lai Wen-Fu T; Chang Chung-Hsun; Tang Yi; Bronson Roederick; Tung Ching-Hsuan
Early diagnosis of osteoarthritis using cathepsin B sensitive near-infrared fluorescent probes.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(3):239-44.
2004: Law Benedict; Curino Alejandro; Bugge Thomas H; Weissleder Ralph; Tung Ching-Hsuan
Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter.
Chemistry & biology 2004;11(1):99-106.
2004: Shah Khalid; Tung Ching-Hsuan; Chang Chung-Hsun; Slootweg Eric; O'Loughlin Terence; Breakefield Xandra O; Weissleder Ralph
In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas.
Cancer research 2004;64(1):273-8.
2004: Tung Ching-Hsuan
Fluorescent peptide probes for in vivo diagnostic imaging.
Biopolymers 2004;76(5):391-403.
2003: Funovics Martin; Weissleder Ralph; Tung Ching-Hsuan
Protease sensors for bioimaging.
Analytical and bioanalytical chemistry 2003;377(6):956-63.
2003: Pham Wellington; Lai Wen-Fu; Weissleder Ralph; Tung Ching-Hsuan
High efficiency synthesis of a bioconjugatable near-infrared fluorochrome.
Bioconjugate chemistry 2003;14(5):1048-51.
2003: Tung Ching-Hsuan; Ho Nan-Hui; Zeng Qing; Tang Yi; Jaffer Farouc A; Reed Guy L; Weissleder Ralph
Novel factor XIII probes for blood coagulation imaging.
Chembiochem : a European journal of chemical biology 2003;4(9):897-9.
2003: Moon Woo Kyung; Lin Yuhui; O'Loughlin Terence; Tang Yi; Kim Dong-Eog; Weissleder Ralph; Tung Ching-Hsuan
Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate.
Bioconjugate chemistry 2003;14(3):539-45.
2003: Lin Yuhui; Weissleder Ralph; Tung Ching-Hsuan
Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging.
Molecular imaging : official journal of the Society for Molecular Imaging 2003;2(2):87-92.
2003: Tung Ching-Hsuan; Weissleder Ralph
Arginine containing peptides as delivery vectors.
Advanced drug delivery reviews 2003;55(2):281-94.
2002: Jaffer Farouc A; Tung Ching-Hsuan; Gerszten Robert E; Weissleder Ralph
In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(11):1929-35.
2002: Tung Ching-Hsuan; Mueller Stephanie; Weissleder Ralph
Novel branching membrane translocational peptide as gene delivery vector.
Bioorganic & medicinal chemistry 2002;10(11):3609-14.
2002: Pham Wellington; Weissleder Ralph; Tung Ching-Hsuan
An azulene dimer as a near-infrared quencher.
Angewandte Chemie (International ed. in English) 2002;41(19):3659-62, 3519.
2002: Ghigo Eric; Capo Christian; Tung Ching-Hsuan; Raoult Didier; Gorvel Jean-Pierre; Mege Jean-Louis
Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4488-95.
2002: Tung Ching-Hsuan; Lin Yuhui; Moon Woo Kyung; Weissleder Ralph
A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging.
Chembiochem : a European journal of chemical biology 2002;3(8):784-6.
2002: Bremer Christoph; Tung Ching-Hsuan; Weissleder Ralph
Molecular imaging of MMP expression and therapeutic MMP inhibition.
Academic radiology 2002;9 Suppl 2():S314-5.
2002: Mahmood Umar; Tung Ching-Hsuan; Tang Yi; Weissleder Ralph
Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice.
Radiology 2002;224(2):446-51.
2002: Ntziachristos Vasilis; Tung Ching-Hsuan; Bremer Christoph; Weissleder Ralph
Fluorescence molecular tomography resolves protease activity in vivo.
Nature medicine 2002;8(7):757-60.
2002: Chen Jiqiu; Tung Ching-Hsuan; Mahmood Umar; Ntziachristos Vasilis; Gyurko Robert; Fishman Mark C; Huang Paul L; Weissleder Ralph
In vivo imaging of proteolytic activity in atherosclerosis.
Circulation 2002;105(23):2766-71.
2002: Lin Yuhui; Weissleder Ralph; Tung Ching-Hsuan
Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation.
Bioconjugate chemistry 2002;13(3):605-10.
2002: Tung Ching-Hsuan; Gerszten Robert E; Jaffer Farouc A; Weissleder Ralph
A novel near-infrared fluorescence sensor for detection of thrombin activation in blood.
Chembiochem : a European journal of chemical biology 2002;3(2-3):207-11.
2002: Bremer Christoph; Tung Ching-Hsuan; Bogdanov Alex; Weissleder Ralph
Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes.
Radiology 2002;222(3):814-8.
2002: Ghigo Eric; Capo Christian; Aurouze Marianne; Tung Ching-Hsuan; Gorvel Jean-Pierre; Raoult Didier; Mege Jean-Louis
Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification.
Infection and immunity 2002;70(3):1501-6.
2002: Marten Katharina; Bremer Christoph; Khazaie Khashayarsha; Sameni Mansoureh; Sloane Bonnie; Tung Ching-Hsuan; Weissleder Ralph
Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice.
Gastroenterology 2002;122(2):406-14.
2001: Bremer C; Bredow S; Mahmood U; Weissleder R; Tung C H
Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model.
Radiology 2001;221(2):523-9.
2001: Bremer C; Tung C H; Weissleder R
In vivo molecular target assessment of matrix metalloproteinase inhibition.
Nature medicine 2001;7(6):743-8.
2001: Bogdanov A; Tung C H; Bredow S; Weissleder R
DNA binding chelates for nonviral gene delivery imaging.
Gene therapy 2001;8(7):515-22.
2001: Weissleder R; Bogdanov A; Tung C H; Weinmann H J
Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging.
Bioconjugate chemistry 2001;12(2):213-9.
2001: Bremer C; Ntziachristos V; Mahmood U; Tung C H; Weissleder R
[Progress in optical imaging]
Der Radiologe 2001;41(2):131-7.
2000: Tung C H; Mahmood U; Bredow S; Weissleder R
In vivo imaging of proteolytic enzyme activity using a novel molecular reporter.
Cancer research 2000;60(17):4953-8.
2000: Bhorade R; Weissleder R; Nakakoshi T; Moore A; Tung C H
Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide.
Bioconjugate chemistry 2000;11(3):301-5.
2000: Lewin M; Carlesso N; Tung C H; Tang X W; Cory D; Scadden D T; Weissleder R
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells.
Nature biotechnology 2000;18(4):410-4.
1999: Tung C H; Bredow S; Mahmood U; Weissleder R
Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging.
Bioconjugate chemistry 1999;10(5):892-6.
1999: Weissleder R; Tung C H; Mahmood U; Bogdanov A
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes.
Nature biotechnology 1999;17(4):375-8.
1999: Josephson L; Tung C H; Moore A; Weissleder R
High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates.
Bioconjugate chemistry 1999;10(2):186-91.

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Ching-Hsuan Tung

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