FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Elaine Tuomanen

Research Profile

Living Beings

Disorders

Physiology

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Jeffrey D Lebensburger; Derek A Persons; Tamara I Pestina; Geli Gao; Thad Howard; Yunming Hu; Melissa Johnson; Elaine I Tuomanen; Russell E Ware; Stanislav S Zakharenko; Jason W Rosch
Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin.
Beth Mann; Daniel J McGoldrick; Caroline A Obert; Granger Ridout; Elaine I Tuomanen; Tim Van Opijnen; Jianmin Wang; Yong-Dong Wang; Andrew Camilli; Robert Carter; Jason W Rosch
Control of virulence by small RNAs in Streptococcus pneumoniae.
Åsa Karlström; Kelli L Boyd; Sarah M Heston; Elaine I Tuomanen; Jonathan A McCullers
Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Elaine Tuomanen (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Jeffrey D Lebensburger; Derek A Persons; Tamara I Pestina; Geli Gao; Thad Howard; Yunming Hu; Melissa Johnson; Elaine I Tuomanen; Russell E Ware; Stanislav S Zakharenko; Jason W Rosch
Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin.
Blood 2012;119(8):1915-21.
2012: Beth Mann; Daniel J McGoldrick; Caroline A Obert; Granger Ridout; Elaine I Tuomanen; Tim Van Opijnen; Jianmin Wang; Yong-Dong Wang; Andrew Camilli; Robert Carter; Jason W Rosch
Control of virulence by small RNAs in Streptococcus pneumoniae.
PLoS pathogens 2012;8(7):e1002788.
2011: Åsa Karlström; Kelli L Boyd; Sarah M Heston; Elaine I Tuomanen; Jonathan A McCullers
Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza.
The Journal of infectious diseases 2011;204(9):1358-66.
2010: Anel Lizcano; Tiffany Chin; Karin Sauer; Elaine I Tuomanen; Carlos Orihuela
Early biofilm formation on microtiter plates is not correlated with the invasive disease potential of Streptococcus pneumoniae.
Microbial pathogenesis 2010;48(3-4):124-30.
2010: Justin A Thornton; Kelly Durick-Eder; Elaine I Tuomanen
Pneumococcal pathogenesis: "innate invasion" yet organ-specific damage.
Journal of molecular medicine (Berlin, Germany) 2010;88(2):103-7.
2010: Jason W Rosch; Angela R Boyd; Ernesto Hinojosa; Tamara Pestina; Yunming Hu; Derek A Persons; Carlos Orihuela; Elaine I Tuomanen
Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease.
The Journal of clinical investigation 2010;120(2):627-35.
2010: Sean P Garrison; Justin A Thornton; Hans Häcker; Richard Webby; Jerold E Rehg; Evan Parganas; Gerard P Zambetti; Elaine I Tuomanen
The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis.
PLoS pathogens 2010;6(12):e1001240.
2009: Carlos Orihuela; Jafar Mahdavi; Justin Thornton; Beth Mann; Karl G Wooldridge; Noha Abouseada; Neil J Oldfield; Tim Self; Dlawer A A Ala'Aldeen; Elaine I Tuomanen
Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models.
The Journal of clinical investigation 2009;119(6):1638-46.
2009: Jason W Rosch; Geli Gao; Granger Ridout; Yong-Dong Wang; Elaine I Tuomanen
Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniae.
Molecular microbiology 2009;72(1):12-25.
2008: Karim C El Kasmi; Joseph E Qualls; John T Pesce; Amber M Smith; Robert W Thompson; Marcela Henao Tamayo; Randall J Basaraba; Till König; Ulrike Schleicher; Mi-Sun Koo; Gilla Kaplan; Katherine A Fitzgerald; Elaine I Tuomanen; Ian M Orme; Thirumala-Devi Kanneganti; Christian Bogdan; Thomas A Wynn; Peter J Murray
Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.
Nature immunology 2008;9(12):1399-406.
2008: Jason W Rosch; Jack Sublett; Geli Gao; Yong-Dong Wang; Elaine I Tuomanen
Calcium efflux is essential for bacterial survival in the eukaryotic host.
Molecular microbiology 2008;70(2):435-44.
2008: Lilian O Moreira; Karim C El Kasmi; Amber M Smith; David Finkelstein; Sophie Fillon; Yun-Gi Kim; Gabriel Núñez; Elaine I Tuomanen; Peter J Murray
The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls.
Cellular microbiology 2008;10(10):2067-77.
2008: Jason W Rosch; Beth Mann; Justin Thornton; Jack Sublett; Elaine I Tuomanen
Convergence of regulatory networks on the pilus locus of Streptococcus pneumoniae.
Infection and immunity 2008;76(7):3187-96.
2008: Peter J Leary; Surender Rajasekaran; R Ray Morrison; Elaine I Tuomanen; Thomas K Chin; Polly A Hofmann
A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.
American journal of physiology. Heart and circulatory physiology 2008;294(6):H2775-84.
2007: Miguela A Caniza; Gabriela Maron; Jonathan A McCullers; Wilfrido A Clara; Rafael Cedillos; Lourdes Dueñas; Sandra Arnold; Bonnie F Williams; Elaine I Tuomanen
Planning and implementation of an infection control training program for healthcare providers in Latin America.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2007;28(12):1328-33.
2007: Caroline A Obert; Geli Gao; Jack Sublett; Elaine I Tuomanen; Carlos Orihuela
Assessment of molecular typing methods to determine invasiveness and to differentiate clones of Streptococcus pneumoniae.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2007;7(6):708-16.
2007: Jason W Rosch; Elaine I Tuomanen
Adapting a diet from sugar to meat: double-dealing genes of Streptococcus pyogenes.
Molecular microbiology 2007;64(2):257-9.
2007: Matthew Marks; Tamika Burns; Maria Abadi; Beza Seyoum; Justin Thornton; Elaine I Tuomanen; Liise-anne Pirofski
Influence of neutropenia on the course of serotype 8 pneumococcal pneumonia in mice.
Infection and immunity 2007;75(4):1586-97.
2007: Joerg R Weber; Elaine I Tuomanen
Cellular damage in bacterial meningitis: an interplay of bacterial and host driven toxicity.
Journal of neuroimmunology 2007;184(1-2):45-52.
2007: Martha L Miller; Geli Gao; Tamara Pestina; Derek Persons; Elaine I Tuomanen
Hypersusceptibility to invasive pneumococcal infection in experimental sickle cell disease involves platelet-activating factor receptor.
The Journal of infectious diseases 2007;195(4):581-4.
2007: Caroline A Obert; Martha L Miller; Jeremy Montgomery; Thomas Adamkiewicz; Elaine I Tuomanen
Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients.
Antimicrobial agents and chemotherapy 2007;51(1):386-9.
2006: Sophie Fillon; Konstantinos Soulis; Surender Rajasekaran; Heather Benedict-Hamilton; Jana N Radin; Carlos Orihuela; Karim C El Kasmi; Gopal Murti; Deepak Kaushal; M Waleed Gaber; Joerg R Weber; Peter J Murray; Elaine I Tuomanen
Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6182-91.
2006: Olaf Hoffmann; Janine Zweigner; Shannon H Smith; Dorette Freyer; Cordula Mahrhofer; Emilie Dagand; Elaine I Tuomanen; Joerg R Weber
Interplay of pneumococcal hydrogen peroxide and host-derived nitric oxide.
Infection and immunity 2006;74(9):5058-66.
2006: Caroline A Obert; Jack Sublett; Deepak Kaushal; Ernesto Hinojosa; Theresa Barton; Elaine I Tuomanen; Carlos Orihuela
Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease.
Infection and immunity 2006;74(8):4766-77.
2006: Carlos Orihuela; Sophie Fillon; S Hope Smith-Sielicki; Karim C El Kasmi; Geli Gao; Konstantinos Soulis; Avinash Patil; Peter J Murray; Elaine I Tuomanen
Cell wall-mediated neuronal damage in early sepsis.
Infection and immunity 2006;74(7):3783-9.
2006: Beth Mann; Carlos Orihuela; Jenni Antikainen; Geli Gao; Jack Sublett; Timo K Korhonen; Elaine I Tuomanen
Multifunctional role of choline binding protein G in pneumococcal pathogenesis.
Infection and immunity 2006;74(2):821-9.
2005: Jana N Radin; Carlos Orihuela; Gopal Murti; Christopher Guglielmo; Peter J Murray; Elaine I Tuomanen
beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae.
Infection and immunity 2005;73(12):7827-35.
2005: Wolfgang Haas; Deepak Kaushal; Jack Sublett; Caroline A Obert; Elaine I Tuomanen
Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae.
Journal of bacteriology 2005;187(23):8205-10.
2005: Sachin Yende; Elaine I Tuomanen; Richard G Wunderink; Alka M Kanaya; Anne B Newman; Tamara Harris; Nathalie de Rekeneire; Stephen B Kritchevsky
Preinfection systemic inflammatory markers and risk of hospitalization due to pneumonia.
American journal of respiratory and critical care medicine 2005;172(11):1440-6.
2005: Andreas Sandgren; Barbara Albiger; Carlos Orihuela; Elaine I Tuomanen; Staffan Normark; Birgitta Henriques Normark
Virulence in mice of pneumococcal clonal types with known invasive disease potential in humans.
The Journal of infectious diseases 2005;192(5):791-800.
2005: Martha L Miller; Caroline A Obert; Geli Gao; Najat C Daw; Patricia Flynn; Elaine I Tuomanen
Cephalosporin-resistant pneumococci and sickle cell disease.
Emerging infectious diseases 2005;11(8):1192-6.
2005: Rensheng Luo; Beth Mann; Elaine I Tuomanen; Richard W Kriwacki
NMR assignment of the R2 domain of pneumococcal choline binding protein A (CbpA).
Journal of biomolecular NMR 2005;32(1):93.
2005: Jagath L Kadurugamuwa; Kshitij Modi; Jun Yu; Kevin P Francis; Carlos Orihuela; Elaine I Tuomanen; Anthony F Purchio; Pamela R Contag
Noninvasive monitoring of pneumococcal meningitis and evaluation of treatment efficacy in an experimental mouse model.
Molecular imaging 2005;4(2):137-42.
2005: Rensheng Luo; Beth Mann; William S Lewis; Arthur Rowe; Richard Heath; Michael L Stewart; Agnes E Hamburger; Sivashankar G Sivakolundu; Eilyn R Lacy; Pamela J Bjorkman; Elaine I Tuomanen; Richard W Kriwacki
Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae.
The EMBO journal 2005;24(1):34-43.
2004: Wolfgang Haas; Jack Sublett; Deepak Kaushal; Elaine I Tuomanen
Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance.
Journal of bacteriology 2004;186(24):8463-71.
2004: Lauren Mitchell; Shannon H Smith; Johann S Braun; Karl-Heinz Herzog; Joerg R Weber; Elaine I Tuomanen
Dual phases of apoptosis in pneumococcal meningitis.
The Journal of infectious diseases 2004;190(11):2039-46.
2004: Carlos Orihuela; Geli Gao; Kevin P Francis; Jun Yu; Elaine I Tuomanen
Tissue-specific contributions of pneumococcal virulence factors to pathogenesis.
The Journal of infectious diseases 2004;190(9):1661-9.
2004: Carina A Rodriguez; Robyn Atkinson; Wally Bitar; Cynthia G Whitney; Kathryn M Edwards; Lauren Mitchell; Juan Li; Jack Sublett; Chin-Shang Li; Tiebin Liu; P Joan Chesney; Elaine I Tuomanen
Tolerance to vancomycin in pneumococci: detection with a molecular marker and assessment of clinical impact.
The Journal of infectious diseases 2004;190(8):1481-7.
2004: Carlos Orihuela; Jana N Radin; Jack Sublett; Geli Gao; Deepak Kaushal; Elaine I Tuomanen
Microarray analysis of pneumococcal gene expression during invasive disease.
Infection and immunity 2004;72(10):5582-96.
2004: Janine Zweigner; Suzanne Jackowski; Shannon H Smith; Marie Van Der Merwe; Joerg R Weber; Elaine I Tuomanen
Bacterial inhibition of phosphatidylcholine synthesis triggers apoptosis in the brain.
The Journal of experimental medicine 2004;200(1):99-106.
2004: Richard J Webby; Daniel Perez; J S Coleman; Yi Guan; J H Knight; Elena A Govorkova; L R McClain-Moss; J S Peiris; Jerold E Rehg; Elaine I Tuomanen; Robert G Webster
Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines.
Lancet 2004;363(9415):1099-103.
2004: Jenny Fernebro; Ingrid Andersson; Jack Sublett; Eva Morfeldt; Rodger Novak; Elaine I Tuomanen; Staffan Normark; Birgitta Henriques Normark
Capsular expression in Streptococcus pneumoniae negatively affects spontaneous and antibiotic-induced lysis and contributes to antibiotic tolerance.
The Journal of infectious diseases 2004;189(2):328-38.
2003: Tera L McCool; Thomas R Cate; Elaine I Tuomanen; Peter Adrian; Tim Mitchell; Jeffrey N Weiser
Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization.
Infection and immunity 2003;71(10):5724-32.
2003: Liquan Xue; Stephan W Morris; Carlos Orihuela; Elaine I Tuomanen; Xiaoli Cui; Renren Wen; Demin Wang
Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells.
Nature immunology 2003;4(9):857-65.
2003: Joerg R Weber; Dorette Freyer; Christian Alexander; Nicolas W J Schröder; Anja Reiss; Carsten Küster; Dagmar Pfeil; Elaine I Tuomanen; Ralf R Schumann
Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein.
Immunity 2003;19(2):269-79.
2003: Joerg R Weber; Philippe Moreillon; Elaine I Tuomanen
Innate sensors for Gram-positive bacteria.
Current opinion in immunology 2003;15(4):408-15.
2003: Carlos Orihuela; Geli Gao; Mackenzie McGee; Jun Yu; Kevin P Francis; Elaine I Tuomanen
Organ-specific models of Streptococcus pneumoniae disease.
Scandinavian journal of infectious diseases 2003;35(9):647-52.
2002: Lauren S Mitchell; Elaine I Tuomanen
Molecular analysis of antibiotic tolerance in pneumococci.
International journal of medical microbiology : IJMM 2002;292(2):75-9.
2002: Johann S Braun; Jack Sublett; Dorette Freyer; Tim Mitchell; John L Cleveland; Elaine I Tuomanen; Joerg R Weber
Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis.
The Journal of clinical investigation 2002;109(1):19-27.
2001: Johann S Braun; Rodger Novak; Peter J Murray; Christine M Eischen; S A Susin; G Kroemer; Annett Halle; Joerg R Weber; Elaine I Tuomanen; John L Cleveland
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus.
The Journal of infectious diseases 2001;184(10):1300-9.
2001: Jonathan A McCullers; Elaine I Tuomanen
Molecular pathogenesis of pneumococcal pneumonia.
Frontiers in bioscience : a journal and virtual library 2001;6():D877-89.
2001: Theresa M Wizemann; Jon H Heinrichs; John E Adamou; Alice L Erwin; Charles Kunsch; Gil H Choi; Steven C Barash; C A Rosen; H R Masure; Elaine I Tuomanen; Antony Gayle; Yambasu Albert Brewah; William D Walsh; Philip R Barren; Raju Lathigra; Mark S Hanson; Solomon Langermann; Syd Johnson; Scott Koenig
Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection.
Infection and immunity 2001;69(3):1593-8.
2001: Birgitta Henriques Normark; Rodger Novak; Ake Ortqvist; Gunilla Källenius; Elaine I Tuomanen; Staffan Normark
Clinical isolates of Streptococcus pneumoniae that exhibit tolerance of vancomycin.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(4):552-8.
2000: Emmanuelle Charpentier; Elaine I Tuomanen
Mechanisms of antibiotic resistance and tolerance in Streptococcus pneumoniae.
Microbes and infection / Institut Pasteur 2000;2(15):1855-64.
2000: K K Gosink; E R Mann; Christopher Guglielmo; Elaine I Tuomanen; HR Masure
Role of novel choline binding proteins in virulence of Streptococcus pneumoniae.
Infection and immunity 2000;68(10):5690-5.
2000: J R Zhang; K E Mostov; M E Lamm; Masanobu Nanno; S Shimida; Makoto Ohwaki; Elaine I Tuomanen
The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells.
Cell 2000;102(6):827-37.
2000: Emmanuelle Charpentier; Rodger Novak; Elaine I Tuomanen
Regulation of growth inhibition at high temperature, autolysis, transformation and adherence in Streptococcus pneumoniae by clpC.
Molecular microbiology 2000;37(4):717-26.
2000: Rodger Novak; Elaine I Tuomanen; Emmanuelle Charpentier
The mystery of psaA and penicillin tolerance in Streptococcus pneumoniae.
Molecular microbiology 2000;36(6):1504-5.
2000: Rodger Novak; Emmanuelle Charpentier; Johann S Braun; E Park; S Murti; Elaine I Tuomanen; R Masure
Extracellular targeting of choline-binding proteins in Streptococcus pneumoniae by a zinc metalloprotease.
Molecular microbiology 2000;36(2):366-76.
2000: Rodger Novak; Emmanuelle Charpentier; Johann S Braun; Elaine I Tuomanen
Signal transduction by a death signal peptide: uncovering the mechanism of bacterial killing by penicillin.
Molecular cell 2000;5(1):49-57.
2000: R M Starzyk; C Rosenow; J Frye; M Leismann; E Rodzinski; SD Putney; Elaine I Tuomanen
Cerebral cell adhesion molecule: a novel leukocyte adhesion determinant on blood-brain barrier capillary endothelium.
The Journal of infectious diseases 2000;181(1):181-7.
1999: Rodger Novak; Elaine I Tuomanen
Pathogenesis of pneumococcal pneumonia.
Seminars in respiratory infections 1999;14(3):209-17.
1999: Rodger Novak; B Henriques; Emmanuelle Charpentier; Staffan Normark; Elaine I Tuomanen
Emergence of vancomycin tolerance in Streptococcus pneumoniae.
Nature 1999;399(6736):590-3.
1999: J R Zhang; I Idanpaan-Heikkila; W Fischer; Elaine I Tuomanen
Pneumococcal licD2 gene is involved in phosphorylcholine metabolism.
Molecular microbiology 1999;31(5):1477-88.
1999: Johann S Braun; Rodger Novak; Karl-Heinz Herzog; S M Bodner; John L Cleveland; Elaine I Tuomanen
Neuroprotection by a caspase inhibitor in acute bacterial meningitis.
Nature medicine 1999;5(3):298-302.
1999: Rodger Novak; A Cauwels; Emmanuelle Charpentier; Elaine I Tuomanen
Identification of a Streptococcus pneumoniae gene locus encoding proteins of an ABC phosphate transporter and a two-component regulatory system.
Journal of bacteriology 1999;181(4):1126-33.
1999: Johann S Braun; Elaine I Tuomanen
Molecular mechanisms of brain damage in bacterial meningitis.
Advances in pediatric infectious diseases 1999;14():49-71.
1998: Rodger Novak; Johann S Braun; Emmanuelle Charpentier; Elaine I Tuomanen
Penicillin tolerance genes of Streptococcus pneumoniae: the ABC-type manganese permease complex Psa.
Molecular microbiology 1998;29(5):1285-96.
1998: A Ring; J N Weiser; Elaine I Tuomanen
Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway.
The Journal of clinical investigation 1998;102(2):347-60.
1998: Jerry L Shenep; Elaine I Tuomanen
Perspective: targeting nitric oxide in the adjuvant therapy of sepsis and meningitis.
The Journal of infectious diseases 1998;177(3):766-9.
1997: I Idänpään-Heikkilä; PM Simon; D Zopf; T Vullo; P Cahill; Karen Sokol; Elaine I Tuomanen
Oligosaccharides interfere with the establishment and progression of experimental pneumococcal pneumonia.
The Journal of infectious diseases 1997;176(3):704-12.
1997: Elaine I Tuomanen
The biology of pneumococcal infection.
Pediatric research 1997;42(3):253-8.
1997: D F Liu; E Phillips; Theresa M Wizemann; Marshall M Siegel; Keiko Tabei; J L Cowell; Elaine I Tuomanen
Characterization of a recombinant fragment that contains a carbohydrate recognition domain of the filamentous hemagglutinin.
Infection and immunity 1997;65(8):3465-8.
1997: A Cauwels; E Wan; M Leismann; Elaine I Tuomanen
Coexistence of CD14-dependent and independent pathways for stimulation of human monocytes by gram-positive bacteria.
Infection and immunity 1997;65(8):3255-60.
1997: Anura Rambukkana; James L Salzer; Peter D Yurchenco; Elaine I Tuomanen
Neural targeting of Mycobacterium leprae mediated by the G domain of the laminin-alpha2 chain.
Cell 1997;88(6):811-21.
1997: Elaine I Tuomanen; HR Masure
Molecular and cellular biology of pneumococcal infection.
Microbial drug resistance (Larchmont, N.Y.) 1997;3(4):297-308.
1996: Elaine I Tuomanen
Molecular and cellular mechanisms of pneumococcal meningitis.
Annals of the New York Academy of Sciences 1996;797():42-52.
1996: Elaine I Tuomanen
Entry of pathogens into the central nervous system.
FEMS microbiology reviews 1996;18(4):289-99.
1996: Jeffrey N Weiser; Z Markiewicz; Elaine I Tuomanen; J H Wani
Relationship between phase variation in colony morphology, intrastrain variation in cell wall physiology, and nasopharyngeal colonization by Streptococcus pneumoniae.
Infection and immunity 1996;64(6):2240-5.
1996: Barbara Spellerberg; C Rosenow; W Sha; Elaine I Tuomanen
Pneumococcal cell wall activates NF-kappa B in human monocytes: aspects distinct from endotoxin.
Microbial pathogenesis 1996;20(5):309-17.
1996: D R Cundell; C Gerard; I Idanpaan-Heikkila; Elaine I Tuomanen; Norma P Gerard
PAf receptor anchors Streptococcus pneumoniae to activated human endothelial cells.
Advances in experimental medicine and biology 1996;416():89-94.
1995: Elaine I Tuomanen
Can microbial pathogenesis team up with immunology?
Trends in microbiology 1995;3(12):456-7.
1995: D Cundell; HR Masure; Elaine I Tuomanen
The molecular basis of pneumococcal infection: a hypothesis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;21 Suppl 3():S204-11.
1995: M van der Flier; N Chhun; Theresa M Wizemann; J Min; J B McCarthy; Elaine I Tuomanen
Adherence of Streptococcus pneumoniae to immobilized fibronectin.
Infection and immunity 1995;63(11):4317-22.
1995: C García Rodríguez; D R Cundell; Elaine I Tuomanen; L F Kolakowski; C Gerard; Norma P Gerard
The role of N-glycosylation for functional expression of the human platelet-activating factor receptor. Glycosylation is required for efficient membrane trafficking.
The Journal of biological chemistry 1995;270(42):25178-84.
1995: D R Cundell; Norma P Gerard; C Gerard; I Idanpaan-Heikkila; Elaine I Tuomanen
Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor.
Nature 1995;377(6548):435-8.
1995: M H Burroughs; L Tsenova-Berkova; Karen Sokol; J Ossig; Elaine I Tuomanen; Gilla Kaplan
Effect of thalidomide on the inflammatory response in cerebrospinal fluid in experimental bacterial meningitis.
Microbial pathogenesis 1995;19(4):245-55.
1995: Barbara Spellerberg; S Prasad; C Cabellos; M Burroughs; P Cahill; Elaine I Tuomanen
Penetration of the blood-brain barrier: enhancement of drug delivery and imaging by bacterial glycopeptides.
The Journal of experimental medicine 1995;182(4):1037-43.
1995: E Rozdzinski; Barbara Spellerberg; M van der Flier; C Bhattacharyya; A I Hoepelman; M A Moran; A Jarpe; S D Putney; R M Starzyk; Elaine I Tuomanen
Peptide from a prokaryotic adhesin blocks leukocyte migration in vitro and in vivo.
The Journal of infectious diseases 1995;172(3):785-93.
1995: Elaine I Tuomanen; R Austrian; HR Masure
Pathogenesis of pneumococcal infection.
The New England journal of medicine 1995;332(19):1280-4.
1995: D R Cundell; Jeffrey N Weiser; J Shen; A Young; Elaine I Tuomanen
Relationship between colonial morphology and adherence of Streptococcus pneumoniae.
Infection and immunity 1995;63(3):757-61.
1995: S M Bhatt; C Cabellos; Joseph B Nadol; Chris Halpin; AM Lauretano; W Z Xu; Elaine I Tuomanen
The impact of dexamethasone on hearing loss in experimental pneumococcal meningitis.
The Pediatric infectious disease journal 1995;14(2):93-6.
1995: E Rozdzinski; Elaine I Tuomanen
Adhesion of microbial pathogens to leukocyte integrins: methods to study ligand mimicry.
Methods in enzymology 1995;253():3-12.
1994: D R Cundell; Elaine I Tuomanen
Receptor specificity of adherence of Streptococcus pneumoniae to human type-II pneumocytes and vascular endothelial cells in vitro.
Microbial pathogenesis 1994;17(6):361-74.
1994: Barbara Spellerberg; Elaine I Tuomanen
The pathophysiology of pneumococcal meningitis.
Annals of medicine 1994;26(6):411-8.
1994: J Sandros; E Rozdzinski; J Zheng; David Cowburn; Elaine I Tuomanen
Lectin domains in the toxin of Bordetella pertussis: selectin mimicry linked to microbial pathogenesis.
Glycoconjugate journal 1994;11(6):501-6.
1994: Assumpta Madu; C Cioffe; Umar Mian; M Burroughs; Elaine I Tuomanen; Martin Mayers; Edward L Schwartz; M Miller
Pharmacokinetics of fluconazole in cerebrospinal fluid and serum of rabbits: validation of an animal model used to measure drug concentrations in cerebrospinal fluid.
Antimicrobial agents and chemotherapy 1994;38(9):2111-5.
1994: Elaine I Tuomanen
Modulation of inflammation in bacterial meningitis.
Israel journal of medical sciences 1994;30(5-6):339-41.
1994: J Sandros; E Rozdzinski; Elaine I Tuomanen
Peptides from pertussis toxin interfere with neutrophil adherence in vitro and counteract inflammation in vivo.
Microbial pathogenesis 1994;16(3):213-20.
1994: E Rozdzinski; Elaine I Tuomanen
Interactions of bacteria with leukocyte integrins.
Methods in enzymology 1994;236():333-45.
1994: W Neal Burnette; W Cieplak; Harvey R Kaslow; R Rappuoli; Elaine I Tuomanen
Recombinant microbial ADP-ribosylating toxins of Bordetella pertussis, Vibrio cholerae, and enterotoxigenic Escherichia coli: structure, function, and toxoid vaccine development.
Bioprocess technology 1994;19():185-203.
1993: E Rozdzinski; T Jones; W Neal Burnette; M Burroughs; Elaine I Tuomanen
Antiinflammatory effects in experimental meningitis of prokaryotic peptides that mimic selectins.
The Journal of infectious diseases 1993;168(6):1422-8.
1993: Jos van Strijp; D G Russell; Elaine I Tuomanen; E J Brown; Samuel D Wright
Ligand specificity of purified complement receptor type three (CD11b/CD18, alpha m beta 2, Mac-1). Indirect effects of an Arg-Gly-Asp (RGD) sequence.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(6):3324-36.
1993: E Rozdzinski; W Neal Burnette; T Jones; V Mar; Elaine I Tuomanen
Prokaryotic peptides that block leukocyte adherence to selectins.
The Journal of experimental medicine 1993;178(3):917-24.
1993: Elaine I Tuomanen; S M Prasad; J S George; A I Hoepelman; P Ibsen; I Heron; R M Starzyk
Reversible opening of the blood-brain barrier by anti-bacterial antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7824-8.
1993: J Sandros; Elaine I Tuomanen
Attachment factors of Bordetella pertussis: mimicry of eukaryotic cell recognition molecules.
Trends in microbiology 1993;1(5):192-6.
1993: S M Prasad; Y Yin; E Rodzinski; Elaine I Tuomanen; HR Masure
Identification of a carbohydrate recognition domain in filamentous hemagglutinin from Bordetella pertussis.
Infection and immunity 1993;61(7):2780-5.
1993: M Burroughs; E Rozdzinski; S Geelen; Elaine I Tuomanen
A structure-activity relationship for induction of meningeal inflammation by muramyl peptides.
The Journal of clinical investigation 1993;92(1):297-302.
1993: M H Burroughs; Y S Chang; Douglas A Gage; Elaine I Tuomanen
Composition of the peptidoglycan of Haemophilus influenzae.
The Journal of biological chemistry 1993;268(16):11594-8.
1993: S Geelen; C Bhattacharyya; Elaine I Tuomanen
The cell wall mediates pneumococcal attachment to and cytopathology in human endothelial cells.
Infection and immunity 1993;61(4):1538-43.
1993: S M Bhatt; AM Lauretano; C Cabellos; Chris Halpin; Robert A Levine; W Z Xu; Joseph B Nadol; Elaine I Tuomanen
Progression of hearing loss in experimental pneumococcal meningitis: correlation with cerebrospinal fluid cytochemistry.
The Journal of infectious diseases 1993;167(3):675-83.
1993: Elaine I Tuomanen
Breaching the blood-brain barrier.
Scientific American 1993;268(2):80-4.
1993: M Burroughs; S Prasad; C Cabellos; Paul M Mendelman; Elaine I Tuomanen
The biologic activities of peptidoglycan in experimental Haemophilus influenzae meningitis.
The Journal of infectious diseases 1993;167(2):464-8.
1992: S Geelen; C Bhattacharyya; Elaine I Tuomanen
Induction of procoagulant activity on human endothelial cells by Streptococcus pneumoniae.
Infection and immunity 1992;60(10):4179-83.
1992: J van't Wout; W Neal Burnette; V L Mar; E Rozdzinski; Samuel D Wright; Elaine I Tuomanen
Role of carbohydrate recognition domains of pertussis toxin in adherence of Bordetella pertussis to human macrophages.
Infection and immunity 1992;60(8):3303-8.
1992: C Cabellos; D E MacIntyre; M Forrest; M Burroughs; S Prasad; Elaine I Tuomanen
Differing roles for platelet-activating factor during inflammation of the lung and subarachnoid space. The special case of Streptococcus pneumoniae.
The Journal of clinical investigation 1992;90(2):612-8.
1992: M Burroughs; C Cabellos; S Prasad; Elaine I Tuomanen
Bacterial components and the pathophysiology of injury to the blood-brain barrier: does cell wall add to the effects of endotoxin in gram-negative meningitis?
The Journal of infectious diseases 1992;165 Suppl 1():S82-5.
1992: A I Hoepelman; Elaine I Tuomanen
Consequences of microbial attachment: directing host cell functions with adhesins.
Infection and immunity 1992;60(5):1729-33.
1992: K Saukkonen; W Neal Burnette; V L Mar; HR Masure; Elaine I Tuomanen
Pertussis toxin has eukaryotic-like carbohydrate recognition domains.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):118-22.
1992: Elaine I Tuomanen
Adjunctive therapy of experimental meningitis: agents other than steroids.
Antibiotics and chemotherapy 1992;45():184-91.
1991: S Bhatt; Chris Halpin; W Hsu; B A Thedinger; Robert A Levine; Elaine I Tuomanen; Joseph B Nadol
Hearing loss and pneumococcal meningitis: an animal model.
The Laryngoscope 1991;101(12 Pt 1):1285-92.
1991: K Saukkonen; C Cabellos; M Burroughs; S Prasad; Elaine I Tuomanen
Integrin-mediated localization of Bordetella pertussis within macrophages: role in pulmonary colonization.
The Journal of experimental medicine 1991;173(5):1143-9.
1991: Martin G Täuber; M Burroughs; U M Niemöller; Herbert Kuster; U Borschberg; Elaine I Tuomanen
Differences of pathophysiology in experimental meningitis caused by three strains of Streptococcus pneumoniae.
The Journal of infectious diseases 1991;163(4):806-11.
1991: Elaine I Tuomanen; S Lindquist; S Sande; M Galleni; K Light; D Gage; S Normark
Coordinate regulation of beta-lactamase induction and peptidoglycan composition by the amp operon.
Science (New York, N.Y.) 1991;251(4990):201-4.
1990: Elaine I Tuomanen
Adjuncts to the therapy of bacterial meningitis.
The Pediatric infectious disease journal 1990;9(10):782-3.
1990: Elaine I Tuomanen; J Schwartz; S Sande
The vir locus affects the response of Bordetella pertussis to antibiotics: phenotypic tolerance and control of autolysis.
The Journal of infectious diseases 1990;162(2):560-3.
1990: David A Relman; Elaine I Tuomanen; Stanley Falkow; D T Golenbock; K Saukkonen; Samuel D Wright
Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis.
Cell 1990;61(7):1375-82.
1990: K Saukkonen; S Sande; C Cioffe; S Wolpe; Barbara Sherry; Anthony Cerami; Elaine I Tuomanen
The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis.
The Journal of experimental medicine 1990;171(2):439-48.
1990: Elaine I Tuomanen; Alexander Tomasz
Mechanism of phenotypic tolerance of nongrowing pneumococci to beta-lactam antibiotics.
Scandinavian journal of infectious diseases. Supplementum 1990;74():102-12.
1989: Elaine I Tuomanen; A Baruch
New antibodies as adjunctive therapies for Gram-positive bacterial meningitis.
The Pediatric infectious disease journal 1989;8(12):923-8.
1989: Robert Cozens; Z Markiewicz; Elaine I Tuomanen
Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria.
Antimicrobial agents and chemotherapy 1989;33(10):1819-21.
1989: Elaine I Tuomanen; K Saukkonen; S Sande; C Cioffe; Samuel D Wright
Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes.
The Journal of experimental medicine 1989;170(3):959-69.
1989: Elaine I Tuomanen; J Schwartz; S Sande; K Light; D Gage
Unusual composition of peptidoglycan in Bordetella pertussis.
The Journal of biological chemistry 1989;264(19):11093-8.
1989: I Riesenfeld-Orn; S Wolpe; J F Garcia-Bustos; M K Hoffmann; Elaine I Tuomanen
Production of interleukin-1 but not tumor necrosis factor by human monocytes stimulated with pneumococcal cell surface components.
Infection and immunity 1989;57(7):1890-3.
1989: David A Relman; M Domenighini; Elaine I Tuomanen; R Rappuoli; Stanley Falkow
Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2637-41.
1989: Elaine I Tuomanen; S Sande
Inhibition of the binding of penicillin to the pneumococcal penicillin-binding proteins (PBPs) by exogenous cell wall peptides.
Journal of general microbiology 1989;135(3):639-43.
1988: Elaine I Tuomanen
Partner drugs: a new outlook for bacterial meningitis.
Annals of internal medicine 1988;109(9):690-2.
1988: Elaine I Tuomanen; Henry Pollack; A Parkinson; M Davidson; R Facklam; R Rich; O Zak
Microbiological and clinical significance of a new property of defective lysis in clinical strains of pneumococci.
The Journal of infectious diseases 1988;158(1):36-43.
1988: Elaine I Tuomanen; H Towbin; G Rosenfelder; D Braun; G Larson; Gunnar Hansson; R Hill
Receptor analogs and monoclonal antibodies that inhibit adherence of Bordetella pertussis to human ciliated respiratory epithelial cells.
The Journal of experimental medicine 1988;168(1):267-77.
1988: Elaine I Tuomanen; Z Markiewicz; Alexander Tomasz
Autolysis-resistant peptidoglycan of anomalous composition in amino-acid-starved Escherichia coli.
Journal of bacteriology 1988;170(3):1373-6.
1987: Elaine I Tuomanen; Robert Cozens
Changes in peptidoglycan composition and penicillin-binding proteins in slowly growing Escherichia coli.
Journal of bacteriology 1987;169(11):5308-10.
1987: Elaine I Tuomanen; J Schwartz
Penicillin-binding protein 7 and its relationship to lysis of nongrowing Escherichia coli.
Journal of bacteriology 1987;169(11):4912-5.
1987: Elaine I Tuomanen; B Hengstler; R Rich; M A Bray; O Zak; Alexander Tomasz
Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis.
The Journal of infectious diseases 1987;155(5):985-90.
1987: Elaine I Tuomanen; R Rich; O Zak
Induction of pulmonary inflammation by components of the pneumococcal cell surface.
The American review of respiratory disease 1987;135(4):869-74.
1986: Elaine I Tuomanen; B Hengstler; O Zak; Alexander Tomasz
Induction of meningeal inflammation by diverse bacterial cell walls.
European journal of clinical microbiology 1986;5(6):682-4.
1986: Elaine I Tuomanen; Robert Cozens; W Tosch; O Zak; A Tomasz
The rate of killing of Escherichia coli by beta-lactam antibiotics is strictly proportional to the rate of bacterial growth.
Journal of general microbiology 1986;132(5):1297-304.
1986: Robert Cozens; Elaine I Tuomanen; W Tosch; O Zak; J Suter; A Tomasz
Evaluation of the bactericidal activity of beta-lactam antibiotics on slowly growing bacteria cultured in the chemostat.
Antimicrobial agents and chemotherapy 1986;29(5):797-802.
1986: Elaine I Tuomanen; B Hengstler; O Zak; Alexander Tomasz
The role of complement in inflammation during experimental pneumococcal meningitis.
Microbial pathogenesis 1986;1(1):15-32.
1985: Elaine I Tuomanen; H Liu; B Hengstler; O Zak; Alexander Tomasz
The induction of meningeal inflammation by components of the pneumococcal cell wall.
The Journal of infectious diseases 1985;151(5):859-68.
1985: Elaine I Tuomanen; Alexander Tomasz; B Hengstler; O Zak
The relative role of bacterial cell wall and capsule in the induction of inflammation in pneumococcal meningitis.
The Journal of infectious diseases 1985;151(3):535-40.
1985: Elaine I Tuomanen; A Weiss; R Rich; F Zak; O Zak
Filamentous hemagglutinin and pertussis toxin promote adherence of Bordetella pertussis to cilia.
Developments in biological standardization 1985;61():197-204.