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Leena Tuomisto

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Vinogradova Lyudmila V; Shatskova Alla B; Tuomisto Leena
Histaminergic modulation of acoustically induced running behavior in rats.
Bosnyakova Daria; Gabova Alexandra; Kuznetsova Galina; Obukhov Yuri; Midzyanovskaya Inna; Salonin Dmitrij; van Rijn Clementina; Coenen Anton; Tuomisto Leene; van Luijtelaar Gilles
Time-frequency analysis of spike-wave discharges using a modified wavelet transform.
Midzyanovskaya I S; Kuznetsova G D; van Luijtelaar E L J M; van Rijn C M; Tuomisto L; Macdonald E
The brain 5HTergic response to an acute sound stress in rats with generalized (absence and audiogenic) epilepsy.

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All Publications

2007: Vinogradova Lyudmila V; Shatskova Alla B; Tuomisto Leena
Histaminergic modulation of acoustically induced running behavior in rats.
Brain research 2007;1148():198-204.
2006: Bosnyakova Daria; Gabova Alexandra; Kuznetsova Galina; Obukhov Yuri; Midzyanovskaya Inna; Salonin Dmitrij; van Rijn Clementina; Coenen Anton; Tuomisto Leene; van Luijtelaar Gilles
Time-frequency analysis of spike-wave discharges using a modified wavelet transform.
Journal of neuroscience methods 2006;154(1-2):80-8.
2006: Midzyanovskaya I S; Kuznetsova G D; van Luijtelaar E L J M; van Rijn C M; Tuomisto L; Macdonald E
The brain 5HTergic response to an acute sound stress in rats with generalized (absence and audiogenic) epilepsy.
Brain research bulletin 2006;69(6):631-8.
2005: Midzyanovskaya I S; Shatskova A B; Sarkisova K Yu; van Luijtelaar G; Tuomisto L; Kuznetsova G D
Convulsive and nonconvulsive epilepsy in rats: effects on behavioral response to novelty stress.
Epilepsy & behavior : E&B 2005;6(4):543-51.
2005: Midzyanovskaya I; Kopilov M; Fedotova E; Kuznetsova G; Tuomisto L
Dual effect of pyrilamine on absence seizures in WAG/Rij rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2005;54 Suppl 1():S40-1.
2005: Airaksinen Anu J; Huotari Marko; Shvetsov Alexander; Vainiotalo Pirjo; Männisto Pekka T; Tuomisto Leena; Bergström Kim A; Vepsäläinen Jouko
Synthesis and biological evaluation of 6/7-exo-methyl-3beta-(4-iodo)phenyltropane-2beta-carboxylic acid methyl esters.
European journal of medicinal chemistry 2005;40(3):299-304.
2005: Birioukova L M; Midzyanovskaya I S; Lensu S; Tuomisto L; van Luijtelaar G
Distribution of D1-like and D2-like dopamine receptors in the brain of genetic epileptic WAG/Rij rats.
Epilepsy research 2005;63(2-3):89-96.
2004: Sohlberg Antti; Lensu Sanna; Jolkkonen Jukka; Tuomisto Leena; Ruotsalainen Ulla; Kuikka Jyrki T
Improving the quality of small animal brain pinhole SPECT imaging by Bayesian reconstruction.
European journal of nuclear medicine and molecular imaging 2004;31(7):986-94.
2004: Lozeva Violina; Montgomery Jane A; Tuomisto Leena; Rocheleau Bernard; Pannunzio Marc; Huet Pierre-Michel; Butterworth Roger F
Increased brain serotonin turnover correlates with the degree of shunting and hyperammonemia in rats following variable portal vein stenosis.
Journal of hepatology 2004;40(5):742-8.
2004: Lipponen A; Lensu S; Tuomisto J; Yamatodani A; Tarhanen J; Tuomisto L
The role of the chorda tympani nerve and histaminergic system in TCDD toxicity.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004;53 Suppl 1():S59-60.
2004: Lozeva-Thomas V; Ahonen P; Chatauret N; Tuomisto L; Butterworth R F
Brain histamine in experimental acute liver failure: effects of L-histidine loading.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004;53 Suppl 1():S55-6.
2003: Lozeva Violina; Tuomisto Leena; Tarhanen Juhani; Butterworth Roger F
Increased concentrations of histamine and its metabolite, tele-methylhistamine and down-regulation of histamine H3 receptor sites in autopsied brain tissue from cirrhotic patients who died in hepatic coma.
Journal of hepatology 2003;39(4):522-7.
2003: Lozeva Violina; Tarhanen Juhani; Attila Martti; Männistö Pekka T; Tuomisto Leena
Brain histamine and histamine H3 receptors following repeated L-histidine administration in rats.
Life sciences 2003;73(12):1491-503.
2003: Alakärppä K; Tupala E; Mantere T; Särkioja T; Räsänen P; Tarhanen J; Tiihonen J; Tuomisto L
Alcoholics show altered histaminergic neurotransmission in several cortical areas--preliminary report.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52 Suppl 1():S37-8.
2003: Lensu S; Tarhanen J; Tuomisto L
Suppressed weight gain following chronic I-histidine loading--involvement of neuronal histaminergic system?
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52 Suppl 1():S35-6.
2003: Midzyanovskaya I S; Tuomisto L
Increased density of H1 histamine receptors in brain regions of rats with absence epilepsy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52 Suppl 1():S29-30.
2003: Tuomisto L; Sturman G; Freeman P; Tarhanen J
Brain histamine turnover and seizure behaviour in two mouse strains: preliminary findings.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52 Suppl 1():S27-8.
2002: Olkkonen Hannu; Pesola Peitsa; Olkkonen Juuso; Valjakka Antti; Tuomisto Leena
EEG noise cancellation by a subspace method based on wavelet decomposition.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(11):MT199-204.
2002: Rinne J O; Anichtchik O V; Eriksson K S; Kaslin J; Tuomisto L; Kalimo H; Röyttä M; Panula P
Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy.
Journal of neurochemistry 2002;81(5):954-60.
2002: Fogel W A; Andrzejewski W; Sasiak K; Granerus G; Lonnqvist B; Tuomisto L; Tarhanen J
Can urinary N-tele methylimidazoleacetic acid (t-MeImAA) serve as a marker of histaminergic activity in hepatic encephalopathy (HE)?
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51 Suppl 1():S63-4.
2002: Lecklin A; Tuomisto L
Inhibition of histamine catabolism suppresses fat intake but not the intake of carbohydrates and protein.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51 Suppl 1():S53-4.
2002: Lensu S; Desiena G; Malmberg-Aiello P; Tuomisto L
Effect of some antiepileptic drugs on brain histaminergic systems in the rat.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51 Suppl 1():S51-2.
2002: Midzyanovskaya I S; Kuznetsova G D; Tuomisto L
Brain histamine in the WAG/Rij rat, an animal model of absence epilepsy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51 Suppl 1():S49-50.
2002: Lozeva V; Tuominen R K; Männistö P T; Tuomisto L
Effect of repeated L-histidine administration on plasma prolactin and growth hormone levels in rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51 Suppl 1():S44-5.
2002: Alakärppä K; Tupala E; Mantere T; Särkioja T; Räsänen P; Tarhanen J; Tiihonen J; Tuomisto L
Effect of alcohol abuse on human brain histamine and tele-methylhistamine.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51 Suppl 1():S40-1.
2001: Tuomisto L; Lozeva V; Valjakka A; Lecklin A
Modifying effects of histamine on circadian rhythms and neuronal excitability.
Behavioural brain research 2001;124(2):129-35.
2001: Huotari M; Passlin M; Nordberg H L; Forsberg M; Kotisaari S; Tuomisto L; Shintani F; Tanaka K F; Reenilä I; Laitinen K; Männistö P T
Effect of intracerebral 6-nitronoradrenaline, an endogenous catechol-O-methyltransferase (COMT) inhibitor, on striatal dopamine metabolism in anaesthetised rats.
Journal of neuroscience methods 2001;109(1):47-52.
2001: Lozeva V; Tuomisto L; Sola D; Plumed C; Hippeläinen M; Butterworth R
Increased density of brain histamine H(1) receptors in rats with portacaval anastomosis and in cirrhotic patients with chronic hepatic encephalopathy.
Hepatology (Baltimore, Md.) 2001;33(6):1370-6.
2001: Lintunen M; Hyytiä P; Sallmen T; Karlstedt K; Tuomisto L; Leurs R; Kiianmaa K; Korpi E R; Panula P
Increased brain histamine in an alcohol-preferring rat line and modulation of ethanol consumption by H(3) receptor mechanisms.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1074-6.
2000: Valjakka A; Jaakkola M; Vartiainen J; Olkkonen H; Semiokhina A; Fedotova I; Virkkala J; Ylikoski J; Tuomisto L
The relationship between audiogenic seizure (AGS) susceptibility and forebrain tone-responsiveness in genetically AGS-prone Wistar rats.
Physiology & behavior 2000;70(3-4):297-309.
2000: Lozeva V; Plumed C; Männistö P T; Tuomisto L
Regional distribution of histamine H3 receptor binding sites in rat brain following L-histidine loading--an autoradiography study.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49 Suppl 1():S47-8.
2000: Lozeva V; Valjakka A; Lecklin A; Olkkonen H; Hippeläinen M; Itkonen M; Plumed C; Tuomisto L
Effects of the histamine H(1) receptor blocker, pyrilamine, on spontaneous locomotor activity of rats with long-term portacaval anastomosis.
Hepatology (Baltimore, Md.) 2000;31(2):336-44.
1999: Harvima R J; Tuomisto L; Husman T
Repeated hand urticaria due to contact with fishfood.
Scandinavian journal of work, environment & health 1999;25(2):151-2.
1999: Eriksson L; Fogel W A; Eklund-Uusitalo S; Tuomisto L; Maslinski C
Is histamine involved in milk ejection in goats?
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 1():S90-1.
1999: Lozeva V; Männistö P T; Tuomisto L
Histamine H3 receptor binding sites in rat cortex following L-histidine loading.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 1():S59-60.
1999: Kovalainen J T; Christiaans J A; Kotisaari S; Laitinen J T; Männistö P T; Tuomisto L; Gynther J
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
Journal of medicinal chemistry 1999;42(7):1193-202.
1999: Olkkonen H; Pesola P; Valjakka A; Tuomisto L
Gain optimized cosine transform domain LMS algorithm for adaptive filtering of EEG.
Computers in biology and medicine 1999;29(2):129-36.
1999: Lecklin A; Eriksson L; Leppäluoto J; Tarhanen J; Tuomisto L
Metoprine-induced thirst and diuresis in Wistar rats.
Acta physiologica Scandinavica 1999;165(3):325-33.
1999: Sallmen T; Beckman A L; Stanton T L; Eriksson K S; Tarhanen J; Tuomisto L; Panula P
Major changes in the brain histamine system of the ground squirrel Citellus lateralis during hibernation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(5):1824-35.
1999: Lozeva V; Anttila E; Tuominen R K; Hippeläinen M; Männistö P T; Tuomisto L
Hypothalamic histamine, growth rate, plasma prolactin and growth hormone levels in rats with long-term portacaval anastomosis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(2):81-5.
1999: Lozeva V; Valjakka A; Anttila E; MacDonald E; Hippeläinen M; Tuomisto L
Brain histamine levels and neocortical slow-wave activity in rats with portacaval anastomosis.
Hepatology (Baltimore, Md.) 1999;29(2):340-6.
1999: Harvima R J; Tuomisto L; Husman T
[The cause of occupational urticaria in hands]
Duodecim; lääketieteellinen aikakauskirja 1999;115(9):1038-40.
1998: Lozeva V; Attila M; Anttila E; Laitinen K; Hippeläinen M; Tuomisto L
Brain histamine H3 receptors in rats with portacaval anastomosis: in vitro and in vivo studies.
Naunyn-Schmiedeberg's archives of pharmacology 1998;358(5):574-81.
1998: Laihia J K; Attila M; Neuvonen K; Pasanen P; Tuomisto L; Jansen C T
Urocanic acid binds to GABA but not to histamine (H1, H2, or H3) receptors.
The Journal of investigative dermatology 1998;111(4):705-6.
1998: Lozeva V; MacDonald E; Belcheva A; Hippeläinen M; Kosunen H; Tuomisto L
Long-term effects of portacaval anastomosis on the 5-hydroxytryptamine, histamine, and catecholamine neurotransmitter systems in rat brain.
Journal of neurochemistry 1998;71(4):1450-6.
1998: Valjakka A; Vartiainen J; Tuomisto L; Tuomisto J T; Olkkonen H; Airaksinen M M
The fasciculus retroflexus controls the integrity of REM sleep by supporting the generation of hippocampal theta rhythm and rapid eye movements in rats.
Brain research bulletin 1998;47(2):171-84.
1998: Lecklin A; Etu-Seppälä P; Stark H; Tuomisto L
Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats.
Brain research 1998;793(1-2):279-88.
1998: Lecklin A; Tuomisto L
The blockade of H1 receptors attenuates the suppression of feeding and diuresis induced by inhibition of histamine catabolism.
Pharmacology, biochemistry, and behavior 1998;59(3):753-8.
1997: Zeiler T; Taivainen A; Rytkönen M; Rautiainen J; Karjalainen H; Mäntyjärvi R; Tuomisto L; Virtanen T
Recombinant allergen fragments as candidate preparations for allergen immunotherapy.
The Journal of allergy and clinical immunology 1997;100(6 Pt 1):721-7.
1996: Nieminen M L; Tuomisto L; Solatunturi E
Platelet taurine concentration and uptake in the Brattleboro diabetes insipidus rat.
Acta medica Okayama 1996;50(4):203-10.
1996: Kiviranta T; Tuomisto L; Jolkkonen J; Airaksinen E M
Vasopressin in the cerebrospinal fluid of febrile children with or without seizures.
Brain & development 1996;18(2):110-3.
1996: Tenhunen J J; Kosunen H; Juvonen P; Heino A; Koski E M; Merasto M E; Takala J; Alhava E; Tuomisto L
Intestinal mucosal microdialysis: histamine release in splanchnic ischemia/reperfusion injury in piglets.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1996;45 Suppl 1():S52-3.
1996: Kiviranta T; Tuomisto L; Airaksinen E M
Osmolality and electrolytes in cerebrospinal fluid and serum of febrile children with and without seizures.
European journal of pediatrics 1996;155(2):120-5.
1996: Tuominen R K; Tuomisto L; Männistö P T
Effect of modified brain histamine contents on prolactin and thyrotropin secretion in male rats.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(2):209-14.
1996: Hendolin H; Nuutinen L; Kokki H; Tuomisto L
Does morphine premedication influence the pain and consumption of postoperative analgesics after total knee arthroplasty?
Acta anaesthesiologica Scandinavica 1996;40(1):81-5.
1996: Valjakka A; Vartiainen J; Kosunen H; Hippeläinen M; Pesola P; Olkkonen H; Airaksinen M M; Tuomisto L
Histaminergic modulation of neocortical spindling and slow-wave activity in freely behaving rats.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(11):1265-80.
1995: Kiviranta T; Airaksinen E M; Tuomisto L
The role of fever on cerebrospinal fluid glucose concentration of children with and without convulsions.
Acta paediatrica (Oslo, Norway : 1992) 1995;84(11):1276-9.
1995: Lecklin A; Tuomisto L
Fluid balance in rats of three different strains after inhibition of histamine catabolism.
Physiology & behavior 1995;58(5):861-7.
1995: Laitinen K S; Tuomisto L; MacDonald E
Effects of a selective alpha 2-adrenoceptor antagonist, atipamezole, on hypothalamic histamine and noradrenaline release in vivo.
European journal of pharmacology 1995;285(3):255-60.
1995: Laitinen K S; Tuomisto L; Laitinen J T
Endogenous serotonin modulates histamine release in the rat hypothalamus as measured by in vivo microdialysis.
European journal of pharmacology 1995;285(2):159-64.
1995: Lozeva V; MacDonald E; Belcheva A; Hippeläinen M; Kosunen H; Fogel A; Maslinski C; Tuomisto L
Long-term effects of portocaval anastomosis in rats on brain levels of histamine and methylhistamine.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44 Suppl 1():S54-5.
1995: Kiviranta T; Tuomisto L; Airaksinen E M
Histamine in cerebrospinal fluid of children with febrile convulsions.
Epilepsia 1995;36(3):276-80.
1995: Lecklin A; Tuomisto L; MacDonald E
Metoprine, an inhibitor of histamine N-methyltransferase but not catechol-O-methyltransferase, suppresses feeding in sated and in food deprived rats.
Methods and findings in experimental and clinical pharmacology 1995;17(1):47-52.
1994: Kiviranta T; Tuomisto L; Airaksinen E M
Diurnal and age-related changes in cerebrospinal fluid tele-methylhistamine levels during infancy and childhood.
Pharmacology, biochemistry, and behavior 1994;49(4):997-1000.
1994: Lecklin A; Järvikylä M; Tuomisto L
The effect of metoprine on glucoprivic feeding induced by 2-deoxy-D-glucose.
Pharmacology, biochemistry, and behavior 1994;49(4):853-7.
1994: Laitinen J T; Laitinen K S; Tuomisto L; Airaksinen M M
Differential regulation of cyclic GMP levels in the frontal cortex and the cerebellum of anesthetized rats by nitric oxide: an in vivo microdialysis study.
Brain research 1994;668(1-2):117-21.
1994: Suonio E; Tuomisto L; Alhava E
Effects of histamine, H1, H2 and Hic receptor antagonists and alpha-fluoromethylhistidine on the growth of human colorectal cancer in the subrenal capsule assay.
Agents and actions 1994;41 Spec No():C118-20.
1994: Tuomisto L; Yamatodani A; Jolkkonen J; Sainio E L; Airaksinen M M
Inhibition of brain histamine synthesis increases food intake and attenuates vasopressin response to salt loading in rats.
Methods and findings in experimental and clinical pharmacology 1994;16(5):355-9.
1994: Porkka-Heiskanen T; Tuomisto L; Ylinen M; Stenberg D
The effect of REM sleep deprivation on histamine concentrations in different brain areas.
Life sciences 1994;54(22):1719-26.
1992: Airaksinen E; Tuomisto L; Riikonen R
The concentrations of GABA, 5-HIAA and HVA in the cerebrospinal fluid of children with infantile spasms and the effects of ACTH treatment.
Brain & development 1992;14(6):386-90.
1992: Onodera K; Tuomisto L; Tacke U; Airaksinen M
Strain differences in regional brain histamine levels between genetically epilepsy-prone and resistant rats.
Methods and findings in experimental and clinical pharmacology 1992;14(1):13-6.
1991: Suojaranta-Ylinen R; Hendolin H; Tuomisto L
The effects of morphine, morphine plus scopolamine, midazolam and promethazine on cerebrospinal fluid histamine concentration and postoperative analgesic consumption.
Agents and actions 1991;33(1-2):212-4.
1991: Tuomisto J T; Unkila M; Pohjanvirta R; Koulu M; Tuomisto L
Effect of a single dose of TCDD on the level of histamine in discrete nuclei in rat brain.
Agents and actions 1991;33(1-2):154-6.
1990: Lecklin A; Tuomisto L
Feed intake after inhibition of histamine catabolism.
Agents and actions 1990;30(1-2):216-9.
1990: Tikkanen T; Raatikainen O; Tuomisto L
Calcium-dependent histidine and histamine release from superfused synaptosomes.
Agents and actions 1990;30(1-2):220-2.
1990: Airaksinen E M; Kiviranta T; Tuomisto L
Taurine: uptake by platelets and plasma concentration of patients with Spielmeyer-Vogt disease.
Progress in clinical and biological research 1990;351():253-7.
1990: Tuomisto L; Ahtee L
[The role of amines in the function of the central nervous system]
Duodecim; lääketieteellinen aikakauskirja 1990;106(22):1566-75.
1989: Tuomisto L; Leppäluoto J
Elevated atrial natriuretic peptide in the brain and heart of Brattleboro rats.
Acta physiologica Scandinavica 1989;136(1):133-4.
1989: Tuomisto L; Antikainen T; Raatikainen O; Kauppinen R
Histidine release from brain slices and synaptosomes.
Agents and actions 1989;27(1-2):123-6.
1989: Harvima R J; Harvima I T; Tuomisto L; Horsmanheimo M; Fräki J E
Comparison of histamine assay methods in measuring in vitro-induced histamine release in patients with allergic rhinitis.
Allergy 1989;44(3):235-9.
1988: Kari E; Tuomisto L; Airaksinen M M; Leino M
[3H]imipramine binding in the retinas of chickens and pigs.
Experimental eye research 1988;47(5):679-88.
1988: Jolkkonen J; Tuomisto L; van Wimersma Greidanus T B; Riekkinen P J
Vasopressin levels in the cerebrospinal fluid of rats with lesions of the paraventricular and suprachiasmatic nuclei.
Neuroscience letters 1988;86(2):184-8.
1988: Nieminen M L; Tuomisto L; Solatunturi E; Eriksson L; Paasonen M K
Taurine in the osmoregulation of the Brattleboro rat.
Life sciences 1988;42(21):2137-43.
1988: Hilakivi L A; Taira T; Hilakivi I; MacDonald E; Tuomisto L; Hellevuo K
Early postnatal treatment with propranolol affects development of brain amines and behavior.
Psychopharmacology 1988;96(3):353-9.
1988: Jolkkonen J; Tuomisto L; Van Wimersma Greidanus T B; Läärä E; Riekkinen P
Effects of osmotic stimuli on vasopressin levels in the CSF of rats.
Peptides 1988;9 Suppl 1():109-11.

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