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Vito Turk

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Dejan Caglič; Mary B Goldring; Christopher Jedeszko; Maik Kindermann; Gregor Kosec; Catherine Miniejew; Urška Repnik; Bonnie F Sloane; Vito Turk; Olga Vasiljeva; K Ulrich Wendt; Boris Turk
The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes.
Aleš Špes; Barbara Sobotic; Vito Turk; Boris Turk
Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines.
Vida Puizdar; Miha Renko; Andrej Sali; Iztok Dolenc; Narayanan Eswar; Ursula Pieper; Tajana Zajc; Eva Zerovnik; Vito Turk
Biochemical characterization and structural modeling of human cathepsin E variant 2 in comparison to the wild-type protein.

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All Publications

2013: Dejan Caglič; Mary B Goldring; Christopher Jedeszko; Maik Kindermann; Gregor Kosec; Catherine Miniejew; Urška Repnik; Bonnie F Sloane; Vito Turk; Olga Vasiljeva; K Ulrich Wendt; Boris Turk
The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes.
Biological chemistry 2013;394(2):307-16.
2012: Aleš Špes; Barbara Sobotic; Vito Turk; Boris Turk
Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines.
Biological chemistry 2012;393(12):1417-31.
2012: Vida Puizdar; Miha Renko; Andrej Sali; Iztok Dolenc; Narayanan Eswar; Ursula Pieper; Tajana Zajc; Eva Zerovnik; Vito Turk
Biochemical characterization and structural modeling of human cathepsin E variant 2 in comparison to the wild-type protein.
Biological chemistry 2012;393(3):177-86.
2012: Dejan Suban; Boris Turk; Vito Turk; Tajana Zajc; Miha Renko; Iztok Dolenc
Cathepsin C and plasma glutamate carboxypeptidase secreted from Fischer rat thyroid cells liberate thyroxin from the N-terminus of thyroglobulin.
Biochimie 2012;94(3):719-26.
2012: Tao Sun; Boris Turk; Vito Turk; Natasa Kopitar-Jerala
Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation.
Frontiers in molecular neuroscience 2012;5():93.
2012: Vito Turk; Olga Vasiljeva; Miha Renko; Veronika Stoka; Tao Sun; Boris Turk; Dusan Turk
Cysteine cathepsins: from structure, function and regulation to new frontiers.
Biochimica et biophysica acta 2012;1824(1):68-88.
2012: Urska Repnik; Veronika Stoka; Vito Turk; Boris Turk
Lysosomes and lysosomal cathepsins in cell death.
Biochimica et biophysica acta 2012;1824(1):22-33.
2011: Georgy Mikhaylov; Evgeniy P Naiden; Christoph Peters; Ivan Psakhye; Sergey G Psakhye; Thomas Reinheckel; Boris Turk; Vito Turk; Liane Babes; Matthew Bogyo; Volya I Itin; Anna A Magaeva; Ursa Mikac; Robert Zeiser; Olga Vasiljeva
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment.
Nature nanotechnology 2011;6(9):594-602.
2011: Eva Žerovnik; Jože Grdadolnik; Gregor Gunčar; Andreja Mirtič; Rosemary A Staniforth; Veronika Stoka; Dusan Turk; Vito Turk
Mechanisms of amyloid fibril formation--focus on domain-swapping.
The FEBS journal 2011;278(13):2263-82.
2011: Clare Jelinska; Peter J Davis; Manca Kenig; Eva Zerovnik; Saša Jenko Kokalj; Gregor Gunčar; Dusan Turk; Vito Turk; David T Clarke; Jonathan P Waltho; Rosemary A Staniforth
Modulation of contact order effects in the two-state folding of stefins A and B.
Biophysical journal 2011;100(9):2268-74.
2011: Saska Ivanova; Uros Gregorc; N Vidergar; Ronald T Javier; D S Bredt; P Vandenabeele; J Pardo; M M Simon; Vito Turk; Lawrence Banks; Boris Turk
MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis.
Cell death & disease 2011;2():e116.
2010: Spela Konjar; Vivien R Sutton; Sabine Hoves; Urska Repnik; Hideo Yagita; Thomas Reinheckel; Christoph Peters; Vito Turk; Boris Turk; Joseph A Trapani; Natasa Kopitar-Jerala
Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.
Immunology 2010;131(2):257-67.
2010: Slavko Ceru; Robert Layfield; Tina Zavasnik-Bergant; Urska Repnik; Natasa Kopitar-Jerala; Vito Turk; Eva Zerovnik
Intracellular aggregation of human stefin B: confocal and electron microscopy study.
Biology of the cell / under the auspices of the European Cell Biology Organization 2010;102(6):319-34.
2010: Urska Pozgan; Dejan Caglic; Blaz Rozman; Hideaki Nagase; Vito Turk; Boris Turk
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis.
Biological chemistry 2010;391(5):571-9.
2010: Veronika Stoka; Vito Turk
A structural network associated with the kallikrein-kinin and renin-angiotensin systems.
Biological chemistry 2010;391(4):443-54.
2010: Katja Skerget; Ajda Taler-Vercic; Andrej Bavdek; Vesna Hodnik; Slavko Ceru; Magda Tusek-Znidaric; Tiina Kumm; Didier Pitsi; Marusa Pompe-Novak; Peep Palumaa; Salvador Soriano; Natasa Kopitar-Jerala; Vito Turk; Gregor Anderluh; Eva Zerovnik
Interaction between oligomers of stefin B and amyloid-beta in vitro and in cells.
The Journal of biological chemistry 2010;285(5):3201-10.
2009: Martina Klarić; Sun Tao; Veronika Stoka; Boris Turk; Vito Turk
Cysteine cathepsins are not critical for TNF-alpha-induced cell death in T98G and U937 cells.
Biochimica et biophysica acta 2009;1794(9):1372-7.
2009: Joze Pungercar; Dejan Caglic; Mohammed Sajid; Marko Dolinar; Olga Vasiljeva; Urska Pozgan; Dusan Turk; Matthew Bogyo; Vito Turk; Boris Turk
Autocatalytic processing of procathepsin B is triggered by proenzyme activity.
The FEBS journal 2009;276(3):660-8.
2009: Dejan Caglic; Gregor Kosec; Lea Bojic; Thomas Reinheckel; Vito Turk; Boris Turk
Murine and human cathepsin B exhibit similar properties: possible implications for drug discovery.
Biological chemistry 2009;390(2):175-9.
2009: Dusan Kordis; Vito Turk
Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes.
BMC evolutionary biology 2009;9():266.
2008: Marko Novinec; Lidija Kovacic; Nives Skrlj; Vito Turk; Lidija Kovačič
Recombinant human SMOCs produced by in vitro refolding: calcium-binding properties and interactions with serum proteins.
Protein expression and purification 2008;62(1):75-82.
2008: Slavko Ceru; Sasa Jenko Kokalj; Sabina Rabzelj; Miha Skarabot; Ion Gutierrez-Aguirre; Natasa Kopitar-Jerala; Gregor Anderluh; Dusan Turk; Vito Turk; Eva Zerovnik
Size and morphology of toxic oligomers of amyloidogenic proteins: a case study of human stefin B.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2008;15(3):147-59.
2008: Gabriela Droga-Mazovec; Lea Bojic; Ana Petelin; Saska Ivanova; Rok Romih; Urska Repnik; Guy S Salvesen; Veronika Stoka; Vito Turk; Boris Turk
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues.
The Journal of biological chemistry 2008;283(27):19140-50.
2008: Sabina Rabzelj; Gabriella Viero; Ion Gutiérrez-Aguirre; Vito Turk; Mauro Dalla Serra; Gregor Anderluh; Eva Zerovnik
Interaction with model membranes and pore formation by human stefin B: studying the native and prefibrillar states.
The FEBS journal 2008;275(10):2455-66.
2008: Alejandro Rabossi; Veronika Stoka; Vida Puizdar; Vito Turk; Luis Quesada-Allue
Purification and characterization of two cysteine peptidases of the Mediterranean fruit fly Ceratitis capitata during metamorphosis.
Archives of insect biochemistry and physiology 2008;68(1):1-13.
2008: Vanina Alvarez; Gregor Kosec; Celso Sant Anna; Vito Turk; Juan J Cazzulo; Boris Turk
Blocking autophagy to prevent parasite differentiation: a possible new strategy for fighting parasitic infections?
Autophagy 2008;4(3):361-3.
2008: Vanina Alvarez; Gregor Kosec; Celso Sant'Anna; Vito Turk; Juan J Cazzulo; Boris Turk
Autophagy is involved in nutritional stress response and differentiation in Trypanosoma cruzi.
The Journal of biological chemistry 2008;283(6):3454-64.
2008: Gareth J Morgan; Silva Giannini; Andrea M Hounslow; C Jeremy Craven; Eva Zerovnik; Vito Turk; Jonathan P Waltho; Rosemary A Staniforth
Exclusion of the native alpha-helix from the amyloid fibrils of a mixed alpha/beta protein.
Journal of molecular biology 2008;375(2):487-98.
2008: Anja Watzke; Gregor Kosec; Maik Kindermann; Volker Jeske; Hans-Peter Nestler; Vito Turk; Boris Turk; K. Ulrich wendt
Selective activity-based probes for cysteine cathepsins.
Angewandte Chemie (International ed. in English) 2008;47(2):406-9.
2007: Lea Bojic; Ana Petelin; Veronika Stoka; Thomas Reinheckel; Christoph Peters; Vito Turk; Boris Turk
Cysteine cathepsins are not involved in Fas/CD95 signalling in primary skin fibroblasts.
FEBS letters 2007;581(27):5185-90.
2007: Dejan Caglic; Joze Pungercar; Gunnar Pejler; Vito Turk; Boris Turk
Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions.
The Journal of biological chemistry 2007;282(45):33076-85.
2007: Saska Ivanova; Urska Repnik; Lawrence Banks; Vito Turk; Boris Turk
Cellular localization of MAGI-1 caspase cleavage products and their role in apoptosis.
Biological chemistry 2007;388(11):1195-8.
2007: Veronika Stoka; Vito Turk; Boris Turk
Lysosomal cysteine cathepsins: signaling pathways in apoptosis.
Biological chemistry 2007;388(6):555-60.
2007: Marko Novinec; Robert N Grass; Wendelin J Stark; Vito Turk; Antonio Baici; Brigita Lenarcic
Interaction between human cathepsins K, L, and S and elastins: mechanism of elastinolysis and inhibition by macromolecular inhibitors.
The Journal of biological chemistry 2007;282(11):7893-902.
2007: Uros Gregorc; Saska Ivanova; Miranda Thomas; Ernesto Guccione; Britt Glaunsinger; Ronald T Javier; Vito Turk; Lawrence Banks; Boris Turk
Cleavage of MAGI-1, a tight junction PDZ protein, by caspases is an important step for cell-cell detachment in apoptosis.
Apoptosis : an international journal on programmed cell death 2007;12(2):343-54.
2007: Veronika Stoka; Vito Turk; Dale E Bredesen
Differential regulation of Smac/DIABLO and Hsp-70 during brain maturation.
Neuromolecular medicine 2007;9(3):255-63.
2007: Olga Vasiljeva; Thomas Reinheckel; Christoph Peters; Dusan Turk; Vito Turk; Boris Turk
Emerging roles of cysteine cathepsins in disease and their potential as drug targets.
Current pharmaceutical design 2007;13(4):387-403.
2007: Iztok Dolenc; Roger H Pain; Vito Turk
Presence of the propeptide on recombinant lysosomal dipeptidase controls both activation and dimerization.
Biological chemistry 2007;388(1):47-51.
2006: Veronika Stoka; Vito Turk; Boris Turk
Do lysosomes induce cell death?
IUBMB life 2006;58(8):493-4.
2006: Marko Mihelic; Cory Teuscher; Vito Turk; Dusan Turk
Mouse stefins A1 and A2 (Stfa1 and Stfa2) differentiate between papain-like endo- and exopeptidases.
FEBS letters 2006;580(17):4195-9.
2006: Veronika Stoka; Vito Turk; Dale E Bredesen
Differential regulation of the intrinsic pathway of apoptosis in brain and liver during ageing.
FEBS letters 2006;580(15):3739-45.
2006: Ales Premzl; Vito Turk; Janko Kos
Intracellular proteolytic activity of cathepsin B is associated with capillary-like tube formation by endothelial cells in vitro.
Journal of cellular biochemistry 2006;97(6):1230-40.
2006: Marko Novinec; Dusan Kordis; Vito Turk; Brigita Lenarcic
Diversity and evolution of the thyroglobulin type-1 domain superfamily.
Molecular biology and evolution 2006;23(4):744-55.
2006: Shin-Rong Hwang; Veronika Stoka; Vito Turk; Vivian Y H Hook
Resistance of cathepsin L compared to elastase to proteolysis when complexed with the serpin endopin 2C, and recovery of cathepsin L activity.
Biochemical and biophysical research communications 2006;340(4):1238-43.
2006: Gregor Kosec; Vanina Alvarez; Fernán Agüero; Daniel Sánchez; Marko Dolinar; Boris Turk; Vito Turk; Juan J Cazzulo
Metacaspases of Trypanosoma cruzi: possible candidates for programmed cell death mediators.
Molecular and biochemical parasitology 2006;145(1):18-28.
2005: Veronika Stoka; Sylvia F Chen; Vito Turk; Dale E Bredesen
Developmental shift in the apostat: comparison of neurones and astrocytes.
FEBS letters 2005;579(27):6147-50.
2005: Sabina Rabzelj; Vito Turk; Eva Zerovnik
In vitro study of stability and amyloid-fibril formation of two mutants of human stefin B (cystatin B) occurring in patients with EPM1.
Protein science : a publication of the Protein Society 2005;14(10):2713-22.
2005: Uros Gregorc; Saska Ivanova; Miranda Thomas; Vito Turk; Lawrence Banks; Boris Turk
hDLG/SAP97, a member of the MAGUK protein family, is a novel caspase target during cell-cell detachment in apoptosis.
Biological chemistry 2005;386(7):705-10.
2005: Tina Zavasnik-Bergant; Urska Repnik; Ana Schweiger; Rok Romih; Matjaz Jeras; Vito Turk; Janko Kos
Differentiation- and maturation-dependent content, localization, and secretion of cystatin C in human dendritic cells.
Journal of leukocyte biology 2005;78(1):122-34.
2005: Gregor Anderluh; Ion Gutierrez-Aguirre; Sabina Rabzelj; Slavko Ceru; Natasa Kopitar-Jerala; Peter Maček; Vito Turk; Eva Zerovnik
Interaction of human stefin B in the prefibrillar oligomeric form with membranes. Correlation with cellular toxicity.
The FEBS journal 2005;272(12):3042-51.
2005: Shin-Rong Hwang; Veronika Stoka; Vito Turk; Vivian Y H Hook
The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.
Biochemistry 2005;44(21):7757-67.
2005: Janko Kos; Andreja Sekirnik; Ales Premzl; Valentina Zavasnik-Bergant; Tomaz Langerholc; Boris Turk; Bernd Werle; Rastko Golouh; Urska Repnik; Matjaz Jeras; Vito Turk
Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues.
Experimental cell research 2005;306(1):103-13.
2005: Uros Gregorc; Andreja Dobersek; Guy S Salvesen; Vito Turk; Boris Turk; Natasa Kopitar-Jerala
A novel caspase-7 specific monoclonal antibody.
Immunology letters 2005;98(1):167-9.
2005: Natasa Kopitar-Jerala; Ana Schweiger; Richard Myers; Vito Turk; Boris Turk
Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins.
FEBS letters 2005;579(10):2149-55.
2005: Veronika Stoka; Boris Turk; Vito Turk
Lysosomal cysteine proteases: structural features and their role in apoptosis.
IUBMB life 2005;57(4-5):347-53.
2005: Tomaz Langerholc; Valentina Zavasnik-Bergant; Boris Turk; Vito Turk; Magnus Abrahamson; Janko Kos
Inhibitory properties of cystatin F and its localization in U937 promonocyte cells.
The FEBS journal 2005;272(6):1535-45.
2005: Olga Vasiljeva; Marko Dolinar; Joze Pungercar; Vito Turk; Boris Turk
Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans.
FEBS letters 2005;579(5):1285-90.
2005: Primoz Meh; Miha Pavsic; Vito Turk; Antonio Baici; Brigita Lenarcic
Dual concentration-dependent activity of thyroglobulin type-1 domain of testican: specific inhibitor and substrate of cathepsin L.
Biological chemistry 2005;386(1):75-83.
2005: Slavko Ceru; Sabina Rabzelj; Natasa Kopitar-Jerala; Vito Turk; Eva Zerovnik
Protein aggregation as a possible cause for pathology in a subset of familial Unverricht-Lundborg disease.
Medical hypotheses 2005;64(5):955-9.
2004: Alejandro Rabossi; Veronika Stoka; Vida Puizdar; Vito Turk; Luis Quesada-Allue
Novel aspartyl proteinase associated to fat body histolysis during Ceratitis capitata early metamorphosis.
Archives of insect biochemistry and physiology 2004;57(2):51-67.
2004: Valentina Zavasnik-Bergant; Ana Schweiger; Tadeja Bevec; Rastko Golouh; Vito Turk; Janko Kos
Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodes.
Immunology 2004;112(3):378-85.
2004: Marko Fonovic; Dieter Brömme; Vito Turk; Boris Turk
Human cathepsin F: expression in baculovirus system, characterization and inhibition by protein inhibitors.
Biological chemistry 2004;385(6):505-9.
2004: Vito Turk; Janko Kos; Boris Turk
Cysteine cathepsins (proteases)--on the main stage of cancer?
Cancer cell 2004;5(5):409-10.
2004: Tina Cirman; Kristina Oresić; Gabriela Droga Mazovec; Vito Turk; John C Reed; Richard Myers; Guy S Salvesen; Boris Turk
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins.
The Journal of biological chemistry 2004;279(5):3578-87.
2003: Pika Mesko Brguljan; Vito Turk; Cimerman Nina; Joze Brzin; Igor Krizaj; Tatjana Popovic
Human brain cathepsin H as a neuropeptide and bradykinin metabolizing enzyme.
Peptides 2003;24(12):1977-84.
2003: Olga Vasiljeva; Marko Dolinar; Vito Turk; Boris Turk
Recombinant human cathepsin H lacking the mini chain is an endopeptidase.
Biochemistry 2003;42(46):13522-8.
2003: J Rozman-Pungercar; Natasa Kopitar-Jerala; Matthew Bogyo; Dusan Turk; Olga Vasiljeva; Ivica Stefe; P Vandenabeele; Dieter Brömme; Vida Puizdar; M Fonović; M Trstenjak-Prebanda; Iztok Dolenc; Vito Turk; Boris Turk
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity.
Cell death and differentiation 2003;10(8):881-8.
2003: Katja Galesa; Roger H Pain; Maarten Jongsma; Vito Turk; Brigita Lenarcic
Structural characterization of thyroglobulin type-1 domains of equistatin.
FEBS letters 2003;539(1-3):120-4.
2003: Ales Premzl; Valentina Zavasnik-Bergant; Vito Turk; Janko Kos
Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro.
Experimental cell research 2003;283(2):206-14.
2003: Dusan Turk; Boris Turk; Vito Turk
Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets?
Biochemical Society symposium 2003;(70):15-30.
2002: Galina Pungercic; Iztok Dolenc; Marko Dolinar; Tadeja Bevec; Sasa Jenko; Sasa Kolaric; Vito Turk
Individual recombinant thyroglobulin type-1 domains are substrates for lysosomal cysteine proteinases.
Biological chemistry 2002;383(11):1809-12.
2002: Eva Zerovnik; Vito Turk; Jonathan P Waltho
Amyloid fibril formation by human stefin B: influence of the initial pH-induced intermediate state.
Biochemical Society transactions 2002;30(4):543-7.
2002: Boris Turk; Veronika Stoka; Jerica Rozman-Pungercar; Tina Cirman; Gabriela Droga-Mazovec; Kristina Oresić; Vito Turk
Apoptotic pathways: involvement of lysosomal proteases.
Biological chemistry 2002;383(7-8):1035-44.
2002: Eva Zerovnik; Valentina Zavasnik-Bergant; Natasa Kopitar-Jerala; Marusa Pompe-Novak; Miha Skarabot; Kenneth Goldie; Maja Ravnikar; Igor Musevic; Vito Turk
Amyloid fibril formation by human stefin B in vitro: immunogold labelling and comparison to stefin A.
Biological chemistry 2002;383(5):859-63.
2002: Eva Zerovnik; Marusa Pompe-Novak; Miha Skarabot; Maja Ravnikar; Igor Musevic; Vito Turk
Human stefin B readily forms amyloid fibrils in vitro.
Biochimica et biophysica acta 2002;1594(1):1-5.
2002: Vito Turk; Boris Turk; Gregor Guncar; Dusan Turk; Janko Kos
Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer.
Advances in enzyme regulation 2002;42():285-303.
2001: Dusan Turk; V Janjić; Igor Stern; Marjetka Podobnik; Doriano Lamba; Søren Weis Dahl; Conni Lauritzen; John Pedersen; Vito Turk; Boris Turk
Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases.
The EMBO journal 2001;20(23):6570-82.
2001: Vito Turk; Boris Turk; Dusan Turk
Lysosomal cysteine proteases: facts and opportunities.
The EMBO journal 2001;20(17):4629-33.
2001: Natasa Kopitar-Jerala; Vida Puizdar; Selma Berbic; Tina Zavasnik-Bergant; Vito Turk
A cathepsin D specific monoclonal antibody.
Immunology letters 2001;77(2):125-6.
2001: Natasa Kopitar-Jerala; Tadeja Bevec; D Barlic-Maganja; Franc Gubensek; Vito Turk
Anti-cathepsin L monoclonal antibodies that distinguish cathepsin L from cathepsin V.
Biological chemistry 2001;382(5):867-70.
2001: Ales Premzl; Vida Puizdar; Valentina Zavasnik-Bergant; Natasa Kopitar-Jerala; Tamara T Lah; Nobuhiko Katunuma; Bonnie F Sloane; Vito Turk; Janko Kos
Invasion of ras-transformed breast epithelial cells depends on the proteolytic activity of cysteine and aspartic proteinases.
Biological chemistry 2001;382(5):853-7.
2001: Valentina Zavasnik-Bergant; Andreja Sekirnik; Rastko Golouh; Vito Turk; Janko Kos
Immunochemical localisation of cathepsin S, cathepsin L and MHC class II-associated p41 isoform of invariant chain in human lymph node tissue.
Biological chemistry 2001;382(5):799-804.
2001: Manca Kenig; Roman Jerala; Louise Kroon-Zitko; Vito Turk; Eva Zerovnik
Major differences in stability and dimerization properties of two chimeric mutants of human stefins.
Proteins 2001;42(4):512-22.
2001: Søren Weis Dahl; T Halkier; Conni Lauritzen; Iztok Dolenc; John Pedersen; Vito Turk; Boris Turk
Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing.
Biochemistry 2001;40(6):1671-8.
2001: Veronika Stoka; Boris Turk; SL Schendel; T H Kim; Tina Cirman; Scott J Snipas; Lisa M Ellerby; Dale E Bredesen; Hudson H Freeze; M Abrahamson; D Bromme; Stan Krajewski; John C Reed; X M Yin; Vito Turk; Guy S Salvesen
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route.
The Journal of biological chemistry 2001;276(5):3149-57.
2000: Natasa Kopitar-Jerala; Franc Gubensek; Vito Turk
Recombinant anti-stefin A Fab fragment: sequence analysis of the variable region and expression in Escherichia coli.
Biological chemistry 2000;381(12):1245-9.
2000: I Klemencic; Adriana K Carmona; Maria Helena S Cezari; Maria A Juliano; Luiz Juliano; Gregor Guncar; Dusan Turk; Igor Krizaj; Vito Turk; Boris Turk
Biochemical characterization of human cathepsin X revealed that the enzyme is an exopeptidase, acting as carboxymonopeptidase or carboxydipeptidase.
European journal of biochemistry / FEBS 2000;267(17):5404-12.
2000: Brigita Lenarcic; G Krishnan; R Borukhovich; B Ruck; Vito Turk; Edward Moczydlowski
Saxiphilin, a saxitoxin-binding protein with two thyroglobulin type 1 domains, is an inhibitor of papain-like cysteine proteinases.
The Journal of biological chemistry 2000;275(20):15572-7.
2000: Borut Strukelj; Brigita Lenarcic; Kristina Gruden; Joze Pungercar; Boris Rogelj; Vito Turk; Dirk Bosch; Maarten Jongsma
Equistatin, a protease inhibitor from the sea anemone actinia equina, is composed of three structural and functional domains.
Biochemical and biophysical research communications 2000;269(3):732-6.
2000: Gregor Guncar; I Klemencic; Boris Turk; Vito Turk; A Karaoglanovic-Carmona; Luiz Juliano; Dusan Turk
Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease.
Structure (London, England : 1993) 2000;8(3):305-13.
2000: Boris Turk; Dusan Turk; Vito Turk
Lysosomal cysteine proteases: more than scavengers.
Biochimica et biophysica acta 2000;1477(1-2):98-111.
2000: Veronika Stoka; Boris Turk; James H McKerrow; Ingemar Björk; Juan J Cazzulo; Vito Turk
The high stability of cruzipain against pH-induced inactivation is not dependent on its C-terminal domain.
FEBS letters 2000;469(1):29-32.
2000: Ana Schweiger; A Staib; Bernd Werle; M Krasovec; Tamara T Lah; Werner Ebert; Vito Turk; Janko Kos
Cysteine proteinase cathepsin H in tumours and sera of lung cancer patients: relation to prognosis and cigarette smoking.
British journal of cancer 2000;82(4):782-8.
2000: Katja Galesa; Borut Strukelj; S Bavec; Vito Turk; Brigita Lenarcic
Cloning and expression of functional equistatin.
Biological chemistry 2000;381(1):85-8.
1999: Natasa Kopitar-Jerala; Vito Turk
A procathepsin D specific monoclonal antibody that recognizes procathepsin D but not cathepsin D.
Immunology letters 1999;70(3):211-2.
1999: J Rozman; J Stojan; R Kuhelj; Vito Turk; Boris Turk
Autocatalytic processing of recombinant human procathepsin B is a bimolecular process.
FEBS letters 1999;459(3):358-62.
1999: Eva Zerovnik; R Virden; Roman Jerala; Louise Kroon-Zitko; Vito Turk; Jonathan P Waltho
Differences in the effects of TFE on the folding pathways of human stefins A and B.
Proteins 1999;36(2):205-16.
1999: Dusan Turk; Gregor Guncar; Vito Turk
The p41 fragment story.
IUBMB life 1999;48(1):7-12.
1999: Natasa Kopitar-Jerala; Roman Jerala; Boris Turk; Franc Gubensek; Vito Turk
Mutational analysis of two stefin A epitopes.
Biological chemistry 1999;380(6):723-6.
1999: Veronika Stoka; Brigita Lenarcic; Juan J Cazzulo; Vito Turk
Cathepsin S and cruzipain are inhibited by equistatin from Actinia equina.
Biological chemistry 1999;380(5):589-92.
1999: Gregor Guncar; Galina Pungercic; I Klemencic; Vito Turk; Dusan Turk
Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.
The EMBO journal 1999;18(4):793-803.
1999: Boris Turk; Iztok Dolenc; Brigita Lenarcic; Igor Krizaj; Vito Turk; J G Bieth; Ingemar Björk
Acidic pH as a physiological regulator of human cathepsin L activity.
European journal of biochemistry / FEBS 1999;259(3):926-32.
1999: Brigita Lenarcic; Vito Turk
Thyroglobulin type-1 domains in equistatin inhibit both papain-like cysteine proteinases and cathepsin D.
The Journal of biological chemistry 1999;274(2):563-6.
1999: Nina Cimerman; M T Prebanda; Boris Turk; Tatjana Popovic; Iztok Dolenc; Vito Turk
Interaction of cystatin C variants with papain and human cathepsins B, H and L.
Journal of enzyme inhibition 1999;14(2):167-74.
1998: D Barlic-Maganja; Marko Dolinar; Vito Turk
The influence of Ala205 on the specificity of cathepsin L produced by dextran sulfate assisted activation of the recombinant proenzyme.
Biological chemistry 1998;379(12):1449-52.
1998: Eva Zerovnik; Roman Jerala; R Virden; Louise Kroon-Zitko; Vito Turk; Jonathan P Waltho
On the mechanism of human stefin B folding: II. Folding from GuHCl unfolded, TFE denatured, acid denatured, and acid intermediate states.
Proteins 1998;32(3):304-13.
1998: Eva Zerovnik; R Virden; Roman Jerala; Vito Turk; Jonathan P Waltho
On the mechanism of human stefin B folding: I. Comparison to homologous stefin A. Influence of pH and trifluoroethanol on the fast and slow folding phases.
Proteins 1998;32(3):296-303.
1998: Veronika Stoka; James H McKerrow; Juan J Cazzulo; Vito Turk
Substrate inhibition of cruzipain is not affected by the C-terminal domain.
FEBS letters 1998;429(2):129-33.
1998: Roman Jerala; Eva Zerovnik; Jurka Kidric; Vito Turk
pH-induced conformational transitions of the propeptide of human cathepsin L. A role for a molten globule state in zymogen activation.
The Journal of biological chemistry 1998;273(19):11498-504.
1998: Eva Zerovnik; Gregor Kopitar; Janko Kos; Vito Turk
Refolding of recombinant sulphonated procathepsin S and of reduced chicken cystatin; implications for renaturation experiments.
Biochimica et biophysica acta 1998;1383(2):211-8.
1998: B Cigić; Igor Krizaj; Bozo Kralj; Vito Turk; Roger H Pain
Stoichiometry and heterogeneity of the pro-region chain in tetrameric human cathepsin C.
Biochimica et biophysica acta 1998;1382(1):143-50.
1998: Gregor Guncar; Marjetka Podobnik; Joze Pungercar; Borut Strukelj; Vito Turk; Dusan Turk
Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function.
Structure (London, England : 1993) 1998;6(1):51-61.
1997: Eva Zerovnik; Nina Cimerman; Janko Kos; Vito Turk; Karl Lohner
Thermal denaturation of human cystatin C and two of its variants; comparison to chicken cystatin.
Biological chemistry 1997;378(10):1199-203.
1997: Marjetka Podobnik; R Kuhelj; Vito Turk; Dusan Turk
Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen.
Journal of molecular biology 1997;271(5):774-88.
1997: Hans-Heinrich Heidtmann; U Salge; Magnus Abrahamson; M Bencina; L Kastelic; Natasa Kopitar-Jerala; Vito Turk; Tamara T Lah
Cathepsin B and cysteine proteinase inhibitors in human lung cancer cell lines.
Clinical & experimental metastasis 1997;15(4):368-81.
1997: Brigita Lenarcic; A Ritonja; Borut Strukelj; Boris Turk; Vito Turk
Equistatin, a new inhibitor of cysteine proteinases from Actinia equina, is structurally related to thyroglobulin type-1 domain.
The Journal of biological chemistry 1997;272(21):13899-903.
1997: Eva Zerovnik; Roman Jerala; Louise Kroon-Zitko; Vito Turk; Karl Lohner
Characterization of the equilibrium intermediates in acid denaturation of human stefin B.
European journal of biochemistry / FEBS 1997;245(2):364-72.
1997: Boris Turk; Vito Turk; Dusan Turk
Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors.
Biological chemistry 1997;378(3-4):141-50.
1997: Ana Schweiger; Borut Stabuc; T Popovíc; Vito Turk; Janko Kos
Enzyme-linked immunosorbent assay for the detection of total cathepsin H in human tissue cytosols and sera.
Journal of immunological methods 1997;201(2):165-72.
1997: Tadeja Bevec; Veronika Stoka; Galina Pungercic; Juan J Cazzulo; Vito Turk
A fragment of the major histocompatibility complex class II-associated p41 invariant chain inhibits cruzipain, the major cysteine proteinase from Trypanosoma cruzi.
FEBS letters 1997;401(2-3):259-61.
1997: Juan J Cazzulo; Veronika Stoka; Vito Turk
Cruzipain, the major cysteine proteinase from the protozoan parasite Trypanosoma cruzi.
Biological chemistry 1997;378(1):1-10.