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Anthony Turner

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David A Hicks; Natalia Z Makova; Natalia N Nalivaeva; Anthony J Turner
Characterisation of acetylcholinesterase release from neuronal cells.
I M Neelov; H A Pearson; NL Tumanova; Anthony J Turner; D S Vasilev; G P Vlasov; Igor A Zhuravin; Maria Bryszewska; NM Dubrovskaya; D Hicks; M Yu Ilyash; A Janaszewska; Barbara Klajnert; N Z Makova; Natalia N Nalivaeva
Molecular properties of lysine dendrimers and their interactions with Aβ-peptides and neuronal cells.
Elena Rybnikova; Ekaterina Tulkova; Anthony J Turner; Anasthasia Galeeva; Tatjana S Gluschenko; Natalia Z Makova; Natalia N Nalivaeva; Michail O Samoilov
Differential expression of ADAM15 and ADAM17 metalloproteases in the rat brain after severe hypobaric hypoxia and hypoxic preconditioning.

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All Publications

2013: David A Hicks; Natalia Z Makova; Natalia N Nalivaeva; Anthony J Turner
Characterisation of acetylcholinesterase release from neuronal cells.
Chemico-biological interactions 2013;203(1):302-8.
2013: I M Neelov; H A Pearson; NL Tumanova; Anthony J Turner; D S Vasilev; G P Vlasov; Igor A Zhuravin; Maria Bryszewska; NM Dubrovskaya; D Hicks; M Yu Ilyash; A Janaszewska; Barbara Klajnert; N Z Makova; Natalia N Nalivaeva
Molecular properties of lysine dendrimers and their interactions with Aβ-peptides and neuronal cells.
Current medicinal chemistry 2013;20(1):134-43.
2012: Elena Rybnikova; Ekaterina Tulkova; Anthony J Turner; Anasthasia Galeeva; Tatjana S Gluschenko; Natalia Z Makova; Natalia N Nalivaeva; Michail O Samoilov
Differential expression of ADAM15 and ADAM17 metalloproteases in the rat brain after severe hypobaric hypoxia and hypoxic preconditioning.
Neuroscience research 2012;72(4):364-73.
2012: Natalia N Nalivaeva; Alasdair R Pickles; Svetlana Plesneva; Daria I Bagrova; Nikolai D Belyaev; NM Dubrovskaya; David I Lewis; Natalia Z Makova; Igor A Zhuravin; Anthony J Turner
Effect of sodium valproate administration on brain neprilysin expression and memory in rats.
Journal of molecular neuroscience : MN 2012;46(3):569-77.
2012: David A Hicks; Natalia N Nalivaeva; Anthony J Turner
Lipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling.
Frontiers in physiology 2012;3():189.
2012: Nicola E Clarke; Martin J Fisher; Daniel W Lambert; Karen E Porter; Anthony J Turner
Angiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling.
PloS one 2012;7(4):e34747.
2012: Nicola E Clarke; Anthony J Turner
Angiotensin-converting enzyme 2: the first decade.
International journal of hypertension 2012;2012():307315.
2011: Heledd H Griffiths; Herbert N Baybutt; Debbie Brown; Carolyn D Jackson; Katherine A B Kellett; Jean C Manson; Pedro Piccardo; Anthony J Turner; Isobel J Whitehouse; Nigel M Hooper
Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and Swedish mutant amyloid precursor protein.
The Journal of biological chemistry 2011;286(38):33489-500.
2011: Kristina Standeven; Anthony J Turner; Anthony J Balmforth; Angela M Carter; P A Cordell; K Hess; Nigel M Hooper; B Lu; Gillian I Rice; D J Scott; Peter J Grant
Neprilysin, obesity and the metabolic syndrome.
International journal of obesity (2005) 2011;35(8):1031-40.
2011: Yue Hong; Stuart Macnab; Louise A Lambert; Anthony J Turner; Adrian Whitehouse; Badar A Usmani
Herpesvirus saimiri-based endothelin-converting enzyme-1 shRNA expression decreases prostate cancer cell invasion and migration.
International journal of cancer. Journal international du cancer 2011;129(3):586-98.
2011: Anthony J Turner; Nikolai D Belyaev; Natalia N Nalivaeva
Mediator: the missing link in amyloid precursor protein nuclear signalling.
EMBO reports 2011;12(3):180-1.
2011: Sandro Sonnino; Alessandro Prinetti; Natalia N Nalivaeva; Anthony J Turner
The Fourth ISN Special Neurochemistry Conference--"Membrane domains in CNS physiology and pathology", Erice, Trapani, Sicily, 22-26 May 2010.
Journal of neurochemistry 2011;116(5):669-70.
2011: David Hicks; Danielle John; Natalia Z Makova; Zaineb Henderson; Natalia N Nalivaeva; Anthony J Turner
Membrane targeting, shedding and protein interactions of brain acetylcholinesterase.
Journal of neurochemistry 2011;116(5):742-6.
2010: Nikolai D Belyaev; Katherine A B Kellett; Caroline Beckett; Natalia Z Makova; Timothy J Revett; Natalia N Nalivaeva; Nigel M Hooper; Anthony J Turner
The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway.
The Journal of biological chemistry 2010;285(53):41443-54.
2010: A R Whyteside; E E Hinsley; L A Lambert; P J McDermott; Anthony J Turner
ECE-1 influences prostate cancer cell invasion via ET-1-mediated FAK phosphorylation and ET-1-independent mechanisms.
Canadian journal of physiology and pharmacology 2010;88(8):850-4.
2010: Zaineb Henderson; Nazia Matto; Danielle John; Natalia N Nalivaeva; Anthony J Turner
Co-localization of PRiMA with acetylcholinesterase in cholinergic neurons of rat brain: an immunocytochemical study.
Brain research 2010;1344():34-42.
2010: Isobel J Whitehouse; Carolyn Jackson; Anthony J Turner; Nigel M Hooper
Prion protein is reduced in aging and in sporadic but not in familial Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;22(3):1023-31.
2010: Daniel W Lambert; Nicola E Clarke; Anthony J Turner
Not just angiotensinases: new roles for the angiotensin-converting enzymes.
Cellular and molecular life sciences : CMLS 2010;67(1):89-98.
2009: Natalia N Nalivaeva; Nikolai D Belyaev; Anthony J Turner
Sodium valproate: an old drug with new roles.
Trends in pharmacological sciences 2009;30(10):509-14.
2009: Clare E Hunt; Anthony J Turner
Cell biology, regulation and inhibition of beta-secretase (BACE-1).
The FEBS journal 2009;276(7):1845-59.
2009: Nicholas D Bland; Philip Robinson; Josie E Thomas; Alan D Shirras; Anthony J Turner; R Elwyn Isaac
Locomotor and geotactic behavior of Drosophila melanogaster over-expressing neprilysin 2.
Peptides 2009;30(3):571-4.
2008: Amy L Cilia La Corte; Angela M Carter; Anthony J Turner; Peter J Grant; Nigel M Hooper
The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2008;9(4):221-5.
2008: Christopher A Rushworth; Jodie L Guy; Anthony J Turner
Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis.
The FEBS journal 2008;275(23):6033-42.
2008: L A Lambert; A R Whyteside; Anthony J Turner; Badar A Usmani
Isoforms of endothelin-converting enzyme-1 (ECE-1) have opposing effects on prostate cancer cell invasion.
British journal of cancer 2008;99(7):1114-20.
2008: Alison R Whyteside; Anthony J Turner
Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences.
FEBS letters 2008;582(16):2382-6.
2008: Jodie L Guy; Daniel W Lambert; Anthony J Turner; Karen E Porter
Functional angiotensin-converting enzyme 2 is expressed in human cardiac myofibroblasts.
Experimental physiology 2008;93(5):579-88.
2008: Natalia N Nalivaeva; Lilia R Fisk; Nikolai D Belyaev; Anthony J Turner
Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease.
Current Alzheimer research 2008;5(2):212-24.
2008: Nigel M Hooper; Anthony J Turner
A new take on prions: preventing Alzheimer's disease.
Trends in biochemical sciences 2008;33(4):151-5.
2008: Daniel W Lambert; Nigel M Hooper; Anthony J Turner
Angiotensin-converting enzyme 2 and new insights into the renin-angiotensin system.
Biochemical pharmacology 2008;75(4):781-6.
2008: Daniel W Lambert; Nicola E Clarke; Nigel M Hooper; Anthony J Turner
Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain.
FEBS letters 2008;582(2):385-90.
2008: Nicholas D Bland; John W Pinney; Josie E Thomas; Anthony J Turner; R Elwyn Isaac
Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships.
BMC evolutionary biology 2008;8():16.
2007: Lilia Fisk; Natalia N Nalivaeva; John P Boyle; Christopher S Peers; Anthony J Turner
Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes.
Neurochemical research 2007;32(10):1741-8.
2007: Edward T Parkin; Nicole T Watt; Ishrut Hussain; Elizabeth A Eckman; Christopher B Eckman; Jean C Manson; Herbert N Baybutt; Anthony J Turner; Nigel M Hooper
Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(26):11062-7.
2007: Anthony J Turner; Natalia N Nalivaeva
New insights into the roles of metalloproteinases in neurodegeneration and neuroprotection.
International review of neurobiology 2007;82():113-35.
2007: Monika Rella; Joann L Elliot; Timothy J Revett; Jerry Lanfear; Anne Phelan; Richard M Jackson; Anthony J Turner; Nigel M Hooper
Identification and characterisation of the angiotensin converting enzyme-3 (ACE3) gene: a novel mammalian homologue of ACE.
BMC genomics 2007;8():194.
2007: Nicholas D Bland; Josie E Thomas; Neil Audsley; Alan D Shirras; Anthony J Turner; R Elwyn Isaac
Expression of NEP2, a soluble neprilysin-like endopeptidase, during embryogenesis in Drosophila melanogaster.
Peptides 2007;28(1):127-35.
2006: NM Dubrovskaya; NN Nalivaeva; Anthony J Turner; Igor A Zhuravin
Effects of an inhibitor of alpha-secretase, which metabolizes the amyloid peptide precursor, on memory formation in rats.
Neuroscience and behavioral physiology 2006;36(9):911-3.
2006: Gillian I Rice; Amy L Jones; Peter J Grant; Angela M Carter; Anthony J Turner; Nigel M Hooper
Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study.
Hypertension 2006;48(5):914-20.
2006: Louise A Dawson; Norman J Maitland; Paul Berry; Anthony J Turner; Badar A Usmani
Expression and localization of endothelin-converting enzyme-1 in human prostate cancer.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):1106-10.
2006: Lilia Fisk; Natalia N Nalivaeva; Anthony J Turner
Regulation of endothelin-converting enzyme-1 expression in human neuroblastoma cells.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):1048-53.
2006: Carolyn D Jackson; Kay Barnes; Shervanthi Homer-Vanniasinkam; Anthony J Turner
Expression and localization of human endothelin-converting enzyme-1 isoforms in symptomatic atherosclerotic disease and saphenous vein.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):794-801.
2006: Alison R Hunter; Anthony J Turner
Expression and localization of endothelin-converting enzyme-1 isoforms in human endothelial cells.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):718-22.
2006: Shuji Awano; Louise A Dawson; Alison R Hunter; Anthony J Turner; Badar A Usmani
Endothelin system in oral squamous carcinoma cells: specific siRNA targeting of ECE-1 blocks cell proliferation.
International journal of cancer. Journal international du cancer 2006;118(7):1645-52.
2006: Monika Rella; Christopher A Rushworth; Jodie L Guy; Anthony J Turner; Thierry Langer; Richard M Jackson
Structure-based pharmacophore design and virtual screening for novel angiotensin converting enzyme 2 inhibitors.
Journal of chemical information and modeling 2006;46(2):708-16.
2006: Anthony J Turner; Natalia N Nalivaeva
Proteinase dysbalance in pathology: the neprilysin (NEP) and angiotensin-converting enzyme (ACE) families.
Cellular and molecular biology (Noisy-le-Grand, France) 2006;52(4):40-8.
2006: Joanna M Cordy; Nigel M Hooper; Anthony J Turner
The involvement of lipid rafts in Alzheimer's disease.
Molecular membrane biology 2006;23(1):111-22.
2005: Fiona J Warner; Rebecca A Lew; A Ian Smith; Daniel W Lambert; Nigel M Hooper; Anthony J Turner
Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells.
The Journal of biological chemistry 2005;280(47):39353-62.
2005: NM Dubrovskaia; NN Nalivaeva; Anthony J Turner; Igor A Zhuravin
[Effect of an inhibitor of alpha-secretase metabolizing amyloid precursor protein on memory in rats].
Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova 2005;55(6):725-8.
2005: Daniel W Lambert; Mike Yarski; Fiona J Warner; Paul Thornhill; Edward T Parkin; A Ian Smith; Nigel M Hooper; Anthony J Turner
Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2).
The Journal of biological chemistry 2005;280(34):30113-9.
2005: Jodie L Guy; Daniel W Lambert; Fiona J Warner; Nigel M Hooper; Anthony J Turner
Membrane-associated zinc peptidase families: comparing ACE and ACE2.
Biochimica et biophysica acta 2005;1751(1):2-8.
2005: Jodie L Guy; Richard M Jackson; Hanne A Jensen; Nigel M Hooper; Anthony J Turner
Identification of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis.
The FEBS journal 2005;272(14):3512-20.
2005: Josie E Thomas; Caroline M Rylett; Ahmet Carhan; Nicholas D Bland; Richard J Bingham; Alan D Shirras; Anthony J Turner; R Elwyn Isaac
Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function.
The Biochemical journal 2005;386(Pt 2):357-66.
2004: Natalia N Nalivaevaa; Lilia Fisk; Ekaterina G Kochkina; Svetlana Plesneva; Igor A Zhuravin; Eva Babusikova; Dusan Dobrota; Anthony J Turner
Effect of hypoxia/ischemia and hypoxic preconditioning/reperfusion on expression of some amyloid-degrading enzymes.
Annals of the New York Academy of Sciences 2004;1035():21-33.
2004: Anthony J Turner; Lilia Fisk; Natalia N Nalivaeva
Targeting amyloid-degrading enzymes as therapeutic strategies in neurodegeneration.
Annals of the New York Academy of Sciences 2004;1035():1-20.
2004: Gareth J Howell; Shane P Herbert; Jennifer M Smith; Shweta Mittar; Lorna C Ewan; Mudassir Mohammed; Alison R Hunter; Nigel Simpson; Anthony J Turner; Ian Zachary; John H Walker; Sreenivasan Ponnambalam
Endothelial cell confluence regulates Weibel-Palade body formation.
Molecular membrane biology 2004;21(6):413-21.
2004: Fiona J Warner; A Ian Smith; Nigel M Hooper; Anthony J Turner
Angiotensin-converting enzyme-2: a molecular and cellular perspective.
Cellular and molecular life sciences : CMLS 2004;61(21):2704-13.
2004: A I Smith; Anthony J Turner
What's new in the renin-angiotensin system?
Cellular and molecular life sciences : CMLS 2004;61(21):2675-6.
2004: Edward T Parkin; Anthony J Turner; Nigel M Hooper
Secretase-mediated cell surface shedding of the angiotensin-converting enzyme.
Protein and peptide letters 2004;11(5):423-32.
2004: Gillian I Rice; Daniel A Thomas; Peter J Grant; Anthony J Turner; Nigel M Hooper
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism.
The Biochemical journal 2004;383(Pt 1):45-51.
2004: Tobias M J Allinson; Edward T Parkin; Thomas P Condon; Sylva L U Schwager; Edward D Sturrock; Anthony J Turner; Nigel M Hooper
The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.
European journal of biochemistry / FEBS 2004;271(12):2539-47.
2004: Anthony J Turner; Julian A Hiscox; Nigel M Hooper
ACE2: from vasopeptidase to SARS virus receptor.
Trends in pharmacological sciences 2004;25(6):291-4.
2004: Louise A Dawson; Norman J Maitland; Anthony J Turner; Badar A Usmani
Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression.
British journal of cancer 2004;90(8):1577-82.
2004: Edward T Parkin; Nicole T Watt; Anthony J Turner; Nigel M Hooper
Dual mechanisms for shedding of the cellular prion protein.
The Journal of biological chemistry 2004;279(12):11170-8.
2004: Shoshana Keynan; Mogher Khamaisi; Rachel Dahan; Kay Barnes; Carolyn D Jackson; Anthony J Turner; Itamar Raz
Increased expression of endothelin-converting enzyme-1c isoform in response to high glucose levels in endothelial cells.
Journal of vascular research 2004;41(2):131-40.
2003: Jodie L Guy; Richard M Jackson; K Ravi Acharya; Edward D Sturrock; Nigel M Hooper; Anthony J Turner
Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence.
Biochemistry 2003;42(45):13185-92.
2003: Tobias M J Allinson; Edward T Parkin; Anthony J Turner; Nigel M Hooper
ADAMs family members as amyloid precursor protein alpha-secretases.
Journal of neuroscience research 2003;74(3):342-52.
2003: Joanna M Cordy; Ishrut Hussain; Colin Dingwall; Nigel M Hooper; Anthony J Turner
Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11735-40.
2003: Edward T Parkin; Fulong Tan; Randal A Skidgel; Anthony J Turner; Nigel M Hooper
The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts.
Journal of cell science 2003;116(Pt 15):3079-87.
2003: Anthony J Turner
Exploring the structure and function of zinc metallopeptidases: old enzymes and new discoveries.
Biochemical Society transactions 2003;31(Pt 3):723-7.
2002: Toshihiro Ansai; Eri Yamamoto; Shuji Awano; Weixian Yu; Anthony J Turner; Tadamichi Takehara
Effects of periodontopathic bacteria on the expression of endothelin-1 in gingival epithelial cells in adult periodontitis.
Clinical science (London, England : 1979) 2002;103 Suppl 48():327S-331S.
2002: Badar A Usmani; Ben Harden; Norman J Maitland; Anthony J Turner
Differential expression of neutral endopeptidase-24.11 (neprilysin) and endothelin-converting enzyme in human prostate cancer cell lines.
Clinical science (London, England : 1979) 2002;103 Suppl 48():314S-317S.
2002: Julie A Carson; Toshihiro Ansai; Shuji Awano; Weixian Yu; Tadamichi Takehara; Anthony J Turner
Characterization of PgPepO, a bacterial homologue of endothelin-converting enzyme-1.
Clinical science (London, England : 1979) 2002;103 Suppl 48():90S-93S.
2002: Canet Rosa; Mark Anderton; Nigel M Hooper; Anthony J Turner; Peter F T Vaughan
Muscarine enhances soluble amyloid precursor protein secretion in human neuroblastoma SH-SY5Y by a pathway dependent on protein kinase C(alpha), src-tyrosine kinase and extracellular signal-regulated kinase but not phospholipase C.
Brain research. Molecular brain research 2002;102(1-2):62-72.
2002: Nigel M Hooper; Anthony J Turner
The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease.
Current medicinal chemistry 2002;9(11):1107-19.
2002: Edward T Parkin; Alison Trew; Graham R Christie; Andrew Faller; Ruth Mayer; Anthony J Turner; Nigel M Hooper
Structure-activity relationship of hydroxamate-based inhibitors on the secretases that cleave the amyloid precursor protein, angiotensin converting enzyme, CD23, and pro-tumor necrosis factor-alpha.
Biochemistry 2002;41(15):4972-81.
2002: Julie A Carson; Anthony J Turner
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
Journal of neurochemistry 2002;81(1):1-8.
2002: Anthony J Turner; Sarah R Tipnis; Jodie L Guy; Gillian Rice; Nigel M Hooper
ACEH/ACE2 is a novel mammalian metallocarboxypeptidase and a homologue of angiotensin-converting enzyme insensitive to ACE inhibitors.
Canadian journal of physiology and pharmacology 2002;80(4):346-53.
2002: Anthony J Turner; Nigel M Hooper
The angiotensin-converting enzyme gene family: genomics and pharmacology.
Trends in pharmacological sciences 2002;23(4):177-83.
2002: Takafumi Arimoto; Toshihiro Ansai; Weixian Yu; Anthony J Turner; Tadamichi Takehara
Kinetic analysis of PPi-dependent phosphofructokinase from Porphyromonas gingivalis.
FEMS microbiology letters 2002;207(1):35-8.
2002: Carolyn D Jackson; Anthony J Turner
Detection and assessment of endothelin-converting enzyme activity.
Methods in molecular biology (Clifton, N.J.) 2002;206():107-24.
2001: Edward T Parkin; Anthony J Turner; Nigel M Hooper
Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase.
The Biochemical journal 2001;358(Pt 1):209-16.
2001: Marwan Alfalah; Edward T Parkin; Ralf Jacob; Edward D Sturrock; R Mentele; Anthony J Turner; Nigel M Hooper; Hassan Y Naim
A point mutation in the juxtamembrane stalk of human angiotensin I-converting enzyme invokes the action of a distinct secretase.
The Journal of biological chemistry 2001;276(24):21105-9.
2001: Natalia N Nalivaeva; Anthony J Turner
Post-translational modifications of proteins: acetylcholinesterase as a model system.
Proteomics 2001;1(6):735-47.
2001: Anthony J Turner; R Elwyn Isaac; David Coates
The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(3):261-9.
2000: GS Cottrell; RJ Hyde; J Lim; Mark R Parsons; Nigel M Hooper; Anthony J Turner
Identification of critical residues in the active site of porcine membrane-bound aminopeptidase P.
Biochemistry 2000;39(49):15129-35.
2000: GS Cottrell; Nigel M Hooper; Anthony J Turner
Cloning, expression, and characterization of human cytosolic aminopeptidase P: a single manganese(II)-dependent enzyme.
Biochemistry 2000;39(49):15121-8.
2000: CD Brown; Kay Barnes; Anthony J Turner
Functional significance of the isoforms of endothelin-converting enzyme-1.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S26-7.
2000: S R Tipnis; Nigel M Hooper; Ralph J Hyde; EH Karran; Graham R Christie; Anthony J Turner
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase.
The Journal of biological chemistry 2000;275(43):33238-43.
2000: Edward T Parkin; Anthony J Turner; Nigel M Hooper
Distribution of Presenilins and Amyloid Precursor Protein (APP) in Detergent-Insoluble Membrane Domains.
Methods in molecular medicine 2000;32():345-60.
2000: S Parvathy; Anthony J Turner; Nigel M Hooper
Inhibition of α-Secretase by Zinc Metalloproteinase Inhibitors.
Methods in molecular medicine 2000;32():203-15.
2000: Nigel M Hooper; Anthony J Turner
Protein processing mechanisms: from angiotensin-converting enzyme to Alzheimer's disease.
Biochemical Society transactions 2000;28(4):441-6.
2000: Nigel M Hooper; Alison Trew; Edward T Parkin; Anthony J Turner
The role of proteolysis in Alzheimer's disease.
Advances in experimental medicine and biology 2000;477():379-90.
2000: Anthony J Turner; CD Brown; Julie A Carson; Kay Barnes
The neprilysin family in health and disease.
Advances in experimental medicine and biology 2000;477():229-40.
1999: Edward T Parkin; Anthony J Turner; Nigel M Hooper
Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein.
The Biochemical journal 1999;344 Pt 1():23-30.
1999: Shuji Awano; Toshihiro Ansai; H Mochizuki; Weixian Yu; K Tanzawa; Anthony J Turner; Tadamichi Takehara
Sequencing, expression and biochemical characterization of the Porphyromonas gingivalis pepO gene encoding a protein homologous to human endothelin-converting enzyme.
FEBS letters 1999;460(1):139-44.
1999: S Parvathy; Ishrut Hussain; EH Karran; Anthony J Turner; Nigel M Hooper
Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
Biochemistry 1999;38(30):9728-34.
1999: Kay Barnes; Anthony J Turner
Endothelin converting enzyme is located on alpha-actin filaments in smooth muscle cells.
Cardiovascular research 1999;42(3):814-22.
1999: Edward T Parkin; Ishrut Hussain; EH Karran; Anthony J Turner; Nigel M Hooper
Characterization of detergent-insoluble complexes containing the familial Alzheimer's disease-associated presenilins.
Journal of neurochemistry 1999;72(4):1534-43.
1999: Anthony J Turner; Nigel M Hooper
Role for ADAM-family proteinases as membrane protein secretases.
Biochemical Society transactions 1999;27(2):255-9.
1999: Nigel M Hooper; S Parvathy; EH Karran; Anthony J Turner
Angiotensin-converting enzyme and the amyloid precursor protein secretases.
Biochemical Society transactions 1999;27(2):229-34.
1998: C E Sansom; MV Hoang; Anthony J Turner
Molecular modelling and site-directed mutagenesis of the active site of endothelin-converting enzyme.
Protein engineering 1998;11(12):1235-41.
1998: Anthony J Turner; Kay Barnes; A Schweizer; Olivier Valdenaire
Isoforms of endothelin-converting enzyme: why and where?
Trends in pharmacological sciences 1998;19(12):483-6.
1998: GS Cottrell; RJ Hyde; Nigel M Hooper; Anthony J Turner
The cloning and functional expression of human pancreatic aminopeptidase P.
Biochemical Society transactions 1998;26(3):S248.
1998: S L Houldsworth; Alison Trew; Nigel M Hooper; Anthony J Turner
Molecular characterisation of the Alzheimer's amyloid precursor protein secretases.
Biochemical Society transactions 1998;26(3):S245.
1998: S Parvathy; Ishrut Hussain; EH Karran; Anthony J Turner; Nigel M Hooper
The amyloid precursor protein (APP) and the angiotensin converting enzyme (ACE) secretase are inhibited by hydroxamic acid-based inhibitors.
Biochemical Society transactions 1998;26(3):S242.
1998: Edward T Parkin; Anthony J Turner; Nigel M Hooper
Detergent solubility and processing of the familial Alzheimer's disease-related presenilin proteins.
Biochemical Society transactions 1998;26(3):S241.
1998: S Parvathy; EH Karran; Anthony J Turner; Nigel M Hooper
The secretases that cleave angiotensin converting enzyme and the amyloid precursor protein are distinct from tumour necrosis factor-alpha convertase.
FEBS letters 1998;431(1):63-5.
1998: CD Brown; Kay Barnes; Anthony J Turner
Anti-peptide antibodies specific to rat endothelin-converting enzyme-1 isoforms reveal isoform localisation and expression.
FEBS letters 1998;424(3):183-7.
1998: S Parvathy; Ishrut Hussain; EH Karran; Anthony J Turner; Nigel M Hooper
Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
Biochemistry 1998;37(6):1680-5.
1998: Kay Barnes; C Brown; Anthony J Turner
Endothelin-converting enzyme: ultrastructural localization and its recycling from the cell surface.
Hypertension 1998;31(1):3-9.
1997: MV Hoang; C E Sansom; Anthony J Turner
Mutagenesis of Glu403 to Cys in rabbit neutral endopeptidase-24.11 (neprilysin) creates a disulphide-linked homodimer: analogy with endothelin-converting enzyme.
The Biochemical journal 1997;327 ( Pt 3)():925-9.
1997: Edward T Parkin; Ishrut Hussain; Anthony J Turner; Nigel M Hooper
The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains.
Journal of neurochemistry 1997;69(5):2179-88.
1997: S Parvathy; S Y Oppong; EH Karran; D R Buckle; Anthony J Turner; Nigel M Hooper
Angiotensin-converting enzyme secretase is inhibited by zinc metalloprotease inhibitors and requires its substrate to be inserted in a lipid bilayer.
The Biochemical journal 1997;327 ( Pt 1)():37-43.
1997: MV Hoang; Anthony J Turner
Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin.
The Biochemical journal 1997;327 ( Pt 1)():23-6.
1997: S Keynan; Aruna Asipu; Nigel M Hooper; Anthony J Turner; G Eric Blair
Stable and temperature-sensitive transformation of baby rat kidney cells by SV40 suppresses expression of membrane dipeptidase.
Oncogene 1997;15(10):1241-5.
1997: S Keynan; Nigel M Hooper; Anthony J Turner
Identification by site-directed mutagenesis of three essential histidine residues in membrane dipeptidase, a novel mammalian zinc peptidase.
The Biochemical journal 1997;326 ( Pt 1)():47-51.
1997: Kay Barnes; Anthony J Turner
The endothelin system and endothelin-converting enzyme in the brain: molecular and cellular studies.
Neurochemical research 1997;22(8):1033-40.
1997: Anthony J Turner; K Tanzawa
Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(5):355-64.
1997: Kay Barnes; B J Walkden; T C Wilkinson; Anthony J Turner
Expression of endothelin-converting enzyme in both neuroblastoma and glial cell lines and its localization in rat hippocampus.
Journal of neurochemistry 1997;68(2):570-7.
1997: Nigel M Hooper; EH Karran; Anthony J Turner
Membrane protein secretases.
The Biochemical journal 1997;321 ( Pt 2)():265-79.
1997: Anthony J Turner; RJ Hyde; J Lim; Nigel M Hooper
Structural studies of aminopeptidase P. A novel cellular peptidase.
Advances in experimental medicine and biology 1997;421():7-16.
1996: Edward T Parkin; Anthony J Turner; Nigel M Hooper
Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes.
The Biochemical journal 1996;319 ( Pt 3)():887-96.
1996: R J Hyde; Nigel M Hooper; Anthony J Turner
Molecular cloning and expression in COS-1 cells of pig kidney aminopeptidase P.
The Biochemical journal 1996;319 ( Pt 1)():197-201.
1996: S Keynan; N T Habgood; Nigel M Hooper; Anthony J Turner
Site-directed mutagenesis of conserved cysteine residues in porcine membrane dipeptidase. Cys 361 alone is involved in disulfide-linked dimerization.
Biochemistry 1996;35(38):12511-7.
1996: M dos S Medeiros; Anthony J Turner
Metabolism and functions of neuropeptide Y.
Neurochemical research 1996;21(9):1125-32.
1996: V M Hoang; C E Sansom; Anthony J Turner
Mutagenesis and modeling of endothelin converting enzyme.
Biochemical Society transactions 1996;24(3):471S.
1996: R J Hyde; Nigel M Hooper; Anthony J Turner
Cloning and functional expression of pig kidney aminopeptidase P.
Biochemical Society transactions 1996;24(3):470S.
1996: Edward T Parkin; Anthony J Turner; Nigel M Hooper
A role for calcium and annexins in the formation of caveolae.
Biochemical Society transactions 1996;24(3):444S.
1996: G S Lloyd; J Hryszko; Nigel M Hooper; Anthony J Turner
Inhibition and metal ion activation of pig kidney aminopeptidase P. Dependence on nature of substrate.
Biochemical pharmacology 1996;52(2):229-36.
1996: Kay Barnes; K Shimada; M Takahashi; K Tanzawa; Anthony J Turner
Metallopeptidase inhibitors induce an up-regulation of endothelin-converting enzyme levels and its redistribution from the plasma membrane to an intracellular compartment.
Journal of cell science 1996;109 ( Pt 5)():919-28.
1996: J Lim; Anthony J Turner
Chemical modification of porcine kidney aminopeptidase P indicates the involvement of two critical histidine residues.
FEBS letters 1996;381(3):188-90.
1996: Anthony J Turner; Liam J Murphy
Molecular pharmacology of endothelin converting enzymes.
Biochemical pharmacology 1996;51(2):91-102.
1996: Anthony J Turner; Liam J Murphy; M S Medeiros; Kay Barnes
Endopeptidase-24.11 (neprilysin) and relatives: twenty years on.
Advances in experimental medicine and biology 1996;389():141-8.
1995: Nigel M Hooper; S Y Oppong; Anthony J Turner
Identification of the site of cleavage in angiotensin converting enzyme by its secretase.
Biochemical Society transactions 1995;23(4):552S.
1995: C Connolly; S Y Oppong; Anthony J Turner; Nigel M Hooper
Purification and characterization of the angiotensin converting enzyme secretase.
Biochemical Society transactions 1995;23(4):551S.
1995: J Lim; Anthony J Turner
Chemical modification of aminopeptidase P: identification of a critical histidyl residue.
Biochemical Society transactions 1995;23(4):549S.
1995: M Takahashi; K Fukuda; K Shimada; Kay Barnes; Anthony J Turner; M Ikeda; H Koike; Y Yamamoto; K Tanzawa
Localization of rat endothelin-converting enzyme to vascular endothelial cells and some secretory cells.
The Biochemical journal 1995;311 ( Pt 2)():657-65.
1995: I A Brewis; M A Ferguson; A Mehlert; Anthony J Turner; Nigel M Hooper
Structures of the glycosyl-phosphatidylinositol anchors of porcine and human renal membrane dipeptidase. Comprehensive structural studies on the porcine anchor and interspecies comparison of the glycan core structures.
The Journal of biological chemistry 1995;270(39):22946-56.
1995: G T Galasko; Y Bao; S J Broomfield; Nigel M Hooper; Anthony J Turner; James M Larner
Circulating factors and insulin resistance. I. A novel myoinositol 1,2-cyclic phosphate phosphoglycan insulin antagonist from human plasma is elevated in noninsulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1995;80(8):2419-29.
1995: S Keynan; Nigel M Hooper; A Felici; Gianfranco Amicosante; Anthony J Turner
The renal membrane dipeptidase (dehydropeptidase I) inhibitor, cilastatin, inhibits the bacterial metallo-beta-lactamase enzyme CphA.
Antimicrobial agents and chemotherapy 1995;39(7):1629-31.
1995: H Murray; H McClaren; Anthony J Turner; A J Kenny
Immunocytochemical studies of an antigen in a human T-cell lymphoma line (Jurkat) recognized by certain monoclonal antibodies to CD-13 (aminopeptidase-N).
Leukemia & lymphoma 1995;17(5-6):501-8.
1995: Kay Barnes; S Doherty; Anthony J Turner
Endopeptidase-24.11 is the integral membrane peptidase initiating degradation of somatostatin in the hippocampus.
Journal of neurochemistry 1995;64(4):1826-32.
1995: G S Lloyd; Anthony J Turner
Aminopeptidase P: cation activation and inhibitor sensitivity are substrate-dependent.
Biochemical Society transactions 1995;23(1):60S.
1995: C E Sansom; V M Hoang; Anthony J Turner
Molecular modeling of the active site of endothelin-converting enzyme.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S75-7.
1995: B J Walkden; Anthony J Turner
Expression of ECE and related membrane peptidases in the EA.hy926 cell line.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S59-60.
1995: Kay Barnes; Liam J Murphy; M Takahashi; K Tanzawa; Anthony J Turner
Localization and biochemical characterization of endothelin-converting enzyme.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S37-9.
1995: M D Medeiros; Anthony J Turner
Metabolic stability of some tachykinin analogues to cell-surface peptidases: roles for endopeptidase-24.11 and aminopeptidase N.
Peptides 1995;16(3):441-7.
1994: K J Greenhough; B J Walkden; Liam J Murphy; H E McLaren; Kay Barnes; Anthony J Turner
Membrane peptidase activity of a human endothelial cell line (EA.hy 926).
Biochemical Society transactions 1994;22(4):454S.
1994: Kay Barnes; Liam J Murphy; Anthony J Turner
Immunoseparation of membrane peptidases from pig lung membranes using magnetic beads.
Biochemical Society transactions 1994;22(4):451S.
1994: N Habgood; H Eastham; Anthony J Turner
Molecular cloning of endopeptidase-24.15 from pig brain.
Biochemical Society transactions 1994;22(4):415S.
1994: I A Brewis; Anthony J Turner; Nigel M Hooper
Activation of the glycosyl-phosphatidylinositol-anchored membrane dipeptidase upon release from pig kidney membranes by phospholipase C.
The Biochemical journal 1994;303 ( Pt 2)():633-8.
1994: Liam J Murphy; R Corder; A I Mallet; Anthony J Turner
Generation by the phosphoramidon-sensitive peptidases, endopeptidase-24.11 and thermolysin, of endothelin-1 and c-terminal fragment from big endothelin-1.
British journal of pharmacology 1994;113(1):137-42.
1994: S Keynan; Nigel M Hooper; Anthony J Turner
Directed mutagenesis of pig renal membrane dipeptidase. His219 is critical but the DHXXH motif is not essential for zinc binding or catalytic activity.
FEBS letters 1994;349(1):50-4.
1994: M D Medeiros; Anthony J Turner
Processing and metabolism of peptide-YY: pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24.11.
Endocrinology 1994;134(5):2088-94.
1994: M dos S Medeiros; Anthony J Turner
Comparison of cholecystokinin metabolism by membrane preparations from the human astrocytoma clone D384 and the neuroblastoma line SH-SY5Y.
Neurochemistry international 1994;24(4):369-77.
1994: Kay Barnes; A J Kenny; Anthony J Turner
Localization of aminopeptidase N and dipeptidyl peptidase IV in pig striatum and in neuronal and glial cell cultures.
The European journal of neuroscience 1994;6(4):531-7.
1994: C T Crilley; Anthony J Turner
Effect of chemical modification of arginyl and histidyl residues on [3H]MK-801 binding to brain synaptic membranes.
Biochemical pharmacology 1994;47(6):961-7.
1994: H Murray; Anthony J Turner; A J Kenny
The aminopeptidase activity in the human T-cell lymphoma line (Jurkat) is not at the cell surface and is not aminopeptidase N (CD-13).
The Biochemical journal 1994;298 ( Pt 2)():353-60.
1994: Anthony J Turner; Kay Barnes
Neuropeptidases: candidate enzymes and techniques for study.
Biochemical Society transactions 1994;22(1):122-7.
1994: Anthony J Turner
Structural and immunological studies of GPI-anchored brush border hydrolases.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):389-94.
1994: Anthony J Turner
PIG-tailed membrane proteins.
Essays in biochemistry 1994;28():113-27.
1994: M S Medeiros; Anthony J Turner
Post-secretory processing of regulatory peptides: the pancreatic polypeptide family as a model example.
Biochimie 1994;76(3-4):283-7.
1993: Anthony J Turner
Endothelin-converting enzymes and other families of metallo-endopeptidases.
Biochemical Society transactions 1993;21 ( Pt 3)(3):697-701.
1993: C T Crilley; Anthony J Turner
Chemical modification of N-methyl-D-aspartate receptors from pig brain.
Biochemical Society transactions 1993;21 ( Pt 3)(3):271S.
1993: S Y Oppong; Anthony J Turner; Nigel M Hooper
Characterization of the soluble and membrane-bound forms of porcine angiotensin converting enzyme.
Biochemical Society transactions 1993;21 ( Pt 3)(3):251S.
1993: M dos S Medeiros; Anthony J Turner
Hydrolysis of cholecystokinin by the human astrocytoma clone D384 and the neuroblastoma line SH-SY5Y.
Biochemical Society transactions 1993;21 ( Pt 3)(3):247S.
1993: G S Lloyd; N T Habgood; Nigel M Hooper; Anthony J Turner
Aminopeptidase P: immunoaffinity purification and molecular characterisation.
Biochemical Society transactions 1993;21 ( Pt 3)(3):236S.
1993: I A Brewis; S Howell; Nigel M Hooper; A J Kenny; Anthony J Turner
Membrane peptidase expression by confluent cultures of Caco-2 cells.
Biochemical Society transactions 1993;21 ( Pt 3)(3):252S.
1993: M dos S Medeiros; Anthony J Turner
Processing and metabolism of peptide YY.
Biochemical Society transactions 1993;21 ( Pt 3)(3):248S.
1993: Kay Barnes; Anthony J Turner; A J Kenny
Co-localisation of substance P and endopeptidase-24.11 in pig substantia nigra: an ultrastructural study.
Biochemical Society transactions 1993;21 ( Pt 3)(3):246S.
1993: Kay Barnes; Anthony J Turner; A J Kenny
An immunoelectron microscopic study of pig substantia nigra shows co-localization of endopeptidase-24.11 with substance P.
Neuroscience 1993;53(4):1073-82.
1993: S Howell; A M Caswell; A J Kenny; Anthony J Turner
Membrane peptidases on human osteoblast-like cells in culture: hydrolysis of calcitonin and hormonal regulation of endopeptidase-24.11.
The Biochemical journal 1993;290 ( Pt 1)():159-64.
1993: S Howell; I A Brewis; Nigel M Hooper; A J Kenny; Anthony J Turner
Mosaic expression of membrane peptidases by confluent cultures of Caco-2 cells.
FEBS letters 1993;317(1-2):109-12.
1993: I A Brewis; M A Ferguson; Anthony J Turner; Nigel M Hooper
Structural determination of the glycolipid anchors of human and porcine membrane dipeptidases.
Biochemical Society transactions 1993;21(1):46S.
1993: I A Brewis; Nigel M Hooper; Anthony J Turner
Identification of the site of attachment of the glycolipid anchor in porcine membrane dipeptidase.
Biochemical Society transactions 1993;21(1):44S.
1993: Liam J Murphy; Anthony J Turner
Endothelin converting enzyme of porcine lung.
Biochemical Society transactions 1993;21(1):27S.
1993: Liam J Murphy; K J Greenhough; Anthony J Turner
Processing and metabolism of endothelin peptides by porcine lung membranes.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S94-7.
1992: TA Williams; Kay Barnes; A J Kenny; Anthony J Turner; Nigel M Hooper
A comparison of the zinc contents and substrate specificities of the endothelial and testicular forms of porcine angiotensin converting enzyme and the preparation of isoenzyme-specific antisera.
The Biochemical journal 1992;288 ( Pt 3)():875-81.
1992: S Howell; A M Caswell; A J Kenny; Anthony J Turner
The regulation of endopeptidase-24.11 expression on human osteoblast-like cells in culture.
Biochemical Society transactions 1992;20(3):282S.
1992: TA Williams; Nigel M Hooper; Kay Barnes; A J Kenny; Anthony J Turner
Immunological studies on the endothelial and testicular forms of angiotensin converting enzyme.
Biochemical Society transactions 1992;20(3):281S.
1992: S Howell; A J Kenny; Anthony J Turner
A survey of membrane peptidases in two human colonic cell lines, Caco-2 and HT-29.
The Biochemical journal 1992;284 ( Pt 2)():595-601.
1992: Kay Barnes; Anthony J Turner; A J Kenny
Membrane localization of endopeptidase-24.11 and peptidyl dipeptidase A (angiotensin converting enzyme) in the pig brain: a study using subcellular fractionation and electron microscopic immunocytochemistry.
Journal of neurochemistry 1992;58(6):2088-96.
1992: Nigel M Hooper; J Hryszko; S Y Oppong; Anthony J Turner
Inhibition by converting enzyme inhibitors of pig kidney aminopeptidase P.
Hypertension 1992;19(3):281-5.
1991: Anthony J Turner; M dos Santos Medeiros; Nigel M Hooper
The molecular biology of GPI-anchored border hydrolases.
Cell biology international reports 1991;15(11):1083-99.
1991: S Howell; H Murray; C S Scott; Anthony J Turner; A J Kenny
A highly sensitive E.L.I.S.A. for endopeptidase-24.11, the common acute-lymphoblastic-leukaemia antigen (CALLA, CD-10), applicable to material of porcine and human origin.
The Biochemical journal 1991;278 ( Pt 2)():417-21.
1991: M dos S Medeiros; Anthony J Balmforth; Peter F T Vaughan; Anthony J Turner
Hydrolysis of atrial and brain natriuretic peptides by the human astrocytoma clone D384 and the neuroblastoma line SH-SY5Y.
Neuroendocrinology 1991;54(3):295-302.
1991: TA Williams; Nigel M Hooper; Anthony J Turner
Characterization of neuronal and endothelial forms of angiotensin converting enzyme in pig brain.
Journal of neurochemistry 1991;57(1):193-9.
1991: P E Millican; A J Kenny; Anthony J Turner
Purification and properties of a neurotensin-degrading endopeptidase from pig brain.
The Biochemical journal 1991;276 ( Pt 3)():583-91.
1991: M dos S Medeiros; Anthony J Turner; A Ljungqvist; K Folkers
Metabolic stability of the LHRH antagonist antide to cell-surface peptidases.
Biochemical and biophysical research communications 1991;176(1):25-30.
1991: K J Greenhough; Anthony J Turner
Aminoacylase I is not a glycolipid-anchored ectoenzyme in pig kidney.
Biochimica et biophysica acta 1991;1076(3):364-8.
1991: S Howell; H Murray; A J Kenny; Anthony J Turner
A sensitive enzyme-linked immunosorbent assay for endopeptidase-24.11.
Biochemical Society transactions 1991;19(1):1S.
1991: Anthony J Turner; K B Widdows; E F Kirkness
Probing the GABAA receptor with antibodies.
Biochemical Society transactions 1991;19(1):124-8.
1991: Nigel M Hooper; S J Broomfield; Anthony J Turner
Characterization of antibodies to the glycosyl-phosphatidylinositol membrane anchors of mammalian proteins.
The Biochemical journal 1991;273(Pt 2)():301-6.
1991: Kay Barnes; A Bourne; P A Cook; Anthony J Turner; A J Kenny
Membrane peptidases in the peripheral nervous system of the pig: their localization by immunohistochemistry at light and electron microscopic levels.
Neuroscience 1991;44(1):245-61.
1990: M dos S Medeiros; Anthony J Balmforth; Peter F T Vaughan; A J Kenny; Anthony J Turner
Hydrolysis of natriuretic peptides by the human astrocytoma clone D384.
Biochemical Society transactions 1990;18(5):888-9.
1990: TA Williams; Nigel M Hooper; A J Kenny; Anthony J Turner
Molecular forms of angiotensin-converting enzyme in brain microvessels.
Biochemical Society transactions 1990;18(5):887.
1990: Nigel M Hooper; J Hryszko; Anthony J Turner
Purification and characterization of pig kidney aminopeptidase P. A glycosyl-phosphatidylinositol-anchored ectoenzyme.
The Biochemical journal 1990;267(2):509-15.
1990: Nigel M Hooper; Jeffrey N Keen; Anthony J Turner
Characterization of the glycosyl-phosphatidylinositol-anchored human renal dipeptidase reveals that it is more extensively glycosylated than the pig enzyme.
The Biochemical journal 1990;265(2):429-33.
1990: Anthony J Turner
Neuropeptide signalling and cell-surface peptidases.
Advances in second messenger and phosphoprotein research 1990;24():467-71.
1989: Anthony J Turner; Nigel M Hooper
Phosphatidylinositol-glycan-tailed membrane proteins: the biochemistry of glycolipid anchors.
Biochemical Society transactions 1989;17(5):864-6.
1989: Nigel M Hooper; Anthony J Turner
Ectoenzymes of the kidney microvillar membrane. Isolation and characterization of the amphipathic form of renal dipeptidase and hydrolysis of its glycosyl-phosphatidylinositol anchor by an activity in plasma.
The Biochemical journal 1989;261(3):811-8.
1989: E F Kirkness; C F Bovenkerk; Tetsufumi Ueda; Anthony J Turner
Phosphorylation of gamma-aminobutyrate (GABA)/benzodiazepine receptors by cyclic AMP-dependent protein kinase.
The Biochemical journal 1989;259(2):613-6.
1989: A Bourne; Kay Barnes; B A Taylor; Anthony J Turner; A J Kenny
Membrane peptidases in the pig choroid plexus and on other cell surfaces in contact with the cerebrospinal fluid.
The Biochemical journal 1989;259(1):69-80.
1989: G M Littlewood; Nigel M Hooper; Anthony J Turner
Ectoenzymes of the kidney microvillar membrane. Affinity purification, characterization and localization of the phospholipase C-solubilized form of renal dipeptidase.
The Biochemical journal 1989;257(2):361-7.
1988: Kay Barnes; R Matsas; Nigel M Hooper; Anthony J Turner; A J Kenny
Endopeptidase-24.11 is striosomally ordered in pig brain and, in contrast to aminopeptidase N and peptidyl dipeptidase A ('angiotensin converting enzyme'), is a marker for a set of striatal efferent fibres.
Neuroscience 1988;27(3):799-817.
1988: Kay Barnes; Anthony J Turner; A J Kenny
Electronmicroscopic immunocytochemistry of pig brain shows that endopeptidase-24.11 is localized in neuronal membranes.
Neuroscience letters 1988;94(1-2):64-9.
1988: E F Kirkness; Anthony J Turner
Antibodies directed against a nonapeptide sequence of the gamma-aminobutyrate (GABA)/benzodiazepine receptor alpha-subunit. Detection of a distinct alpha-like subunit in pig cerebral cortex but not cerebellum.
The Biochemical journal 1988;256(1):291-4.
1988: E F Kirkness; Anthony J Turner
The stimulatory effects of secobarbital and pregnanolone on the GABAA receptor can be blocked selectively.
European journal of pharmacology 1988;150(3):385-8.
1988: Nigel M Hooper; Anthony J Turner
Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor.
The Biochemical journal 1988;250(3):865-9.
1988: Nigel M Hooper; Anthony J Turner
Ectoenzymes of the kidney microvillar membrane. Aminopeptidase P is anchored by a glycosyl-phosphatidylinositol moiety.
FEBS letters 1988;229(2):340-4.
1988: E F Kirkness; Anthony J Turner
Characterization of a cytosolic protein (P36) isolated from pig brain by benzodiazepine-affinity chromatography.
Journal of neurochemistry 1988;50(2):356-65.
1988: G M Littlewood; L L Iversen; Anthony J Turner
Neuropeptides and their peptidases: Functional considerations.
Neurochemistry international 1988;12(3):383-9.
1987: Nigel M Hooper; J Keen; D J Pappin; Anthony J Turner
Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane.
The Biochemical journal 1987;247(1):85-93.
1987: K B Widdows; E F Kirkness; Anthony J Turner
Modification of the GABA/benzodiazepine receptor with the arginine reagent, 2,3-butanedione.
FEBS letters 1987;222(1):125-8.
1987: Nigel M Hooper; M G Low; Anthony J Turner
Renal dipeptidase is one of the membrane proteins released by phosphatidylinositol-specific phospholipase C.
The Biochemical journal 1987;244(2):465-9.
1987: Anthony J Turner; J Hryszko; Nigel M Hooper; M J Dowdall
Purification and characterization of a peptidyl dipeptidase resembling angiotensin converting enzyme from the electric organ of Torpedo marmorata.
Journal of neurochemistry 1987;48(3):910-6.
1986: R Matsas; A J Kenny; Anthony J Turner
An immunohistochemical study of endopeptidase-24.11 ("enkephalinase") in the pig nervous system.
Neuroscience 1986;18(4):991-1012.
1985: R Matsas; S L Stephenson; J Hryszko; A J Kenny; Anthony J Turner
The metabolism of neuropeptides. Phase separation of synaptic membrane preparations with Triton X-114 reveals the presence of aminopeptidase N.
The Biochemical journal 1985;231(2):445-9.
1985: R Matsas; Marcus Rattray; A J Kenny; Anthony J Turner
The metabolism of neuropeptides. Endopeptidase-24.11 in human synaptic membrane preparations hydrolyses substance P.
The Biochemical journal 1985;228(2):487-92.
1985: Anthony J Turner; R Matsas; A J Kenny
Are there neuropeptide-specific peptidases?
Biochemical pharmacology 1985;34(9):1347-56.
1985: Anthony J Turner; R Matsas; A J Kenny
Endopeptidase-24.11 and neuropeptide metabolism.
Biochemical Society transactions 1985;13(1):39-42.
1985: Anthony J Turner
Membrane peptidases of the nervous system.
Neurochemistry international 1985;7(2):385-7.
1984: R Matsas; A J Kenny; Anthony J Turner
The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11.
The Biochemical journal 1984;223(2):433-40.
1984: R Matsas; Anthony J Turner; A J Kenny
Endopeptidase-24.11 and aminopeptidase activity in brain synaptic membranes are jointly responsible for the hydrolysis of cholecystokinin octapeptide (CCK-8).
FEBS letters 1984;175(1):124-8.
1983: J M Relton; N S Gee; R Matsas; Anthony J Turner; A J Kenny
Purification of endopeptidase-24.11 ('enkephalinase') from pig brain by immunoadsorbent chromatography.
The Biochemical journal 1983;215(3):519-23.
1983: R Matsas; I S Fulcher; A J Kenny; Anthony J Turner
Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(10):3111-5.
1982: I S Fulcher; R Matsas; Anthony J Turner; A J Kenny
Kidney neutral endopeptidase and the hydrolysis of enkephalin by synaptic membranes show similar sensitivity to inhibitors.
The Biochemical journal 1982;203(2):519-22.