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Michael Turner

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Paul Capewell; Stephen L Hajduk; Jayne Raper; C Michael R Turner; Nicola J Veitch; Matthew Berriman; Annette MacLeod
Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.
Esron Karimuribo; Liam J Morrison; Alana Black; C Michael R Turner; Dominic M Kambarage; Keith T Ballingall
Analysis of host genetic factors influencing African trypanosome species infection in a cohort of Tanzanian Bos indicus cattle.
Francisca Mutapi; C Bourke; Yvonne M Harcus; Nicholas Midzi; Takafira MDULUZA; C Michael R Turner; Richard J S Burchmore; Rick M Maizels
Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4.

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All Publications

2011: Paul Capewell; Stephen L Hajduk; Jayne Raper; C Michael R Turner; Nicola J Veitch; Matthew Berriman; Annette MacLeod
Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.
PLoS neglected tropical diseases 2011;5(9):e1287.
2011: Esron Karimuribo; Liam J Morrison; Alana Black; C Michael R Turner; Dominic M Kambarage; Keith T Ballingall
Analysis of host genetic factors influencing African trypanosome species infection in a cohort of Tanzanian Bos indicus cattle.
Veterinary parasitology 2011;179(1-3):35-42.
2011: Francisca Mutapi; C Bourke; Yvonne M Harcus; Nicholas Midzi; Takafira MDULUZA; C Michael R Turner; Richard J S Burchmore; Rick M Maizels
Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4.
Parasite immunology 2011;33(3):181-92.
2010: Rudo Kieft; Paul Capewell; C Michael R Turner; Nicola J Veitch; Annette MacLeod; Stephen L Hajduk
Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factor.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(37):16137-41.
2010: Liam J Morrison; Sarah McLellan; Lindsay Sweeney; Chi N Chan; Annette MacLeod; Andy Tait; C Michael R Turner
Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection.
Infection and immunity 2010;78(3):1096-108.
2010: Mhairi L Stewart; Richard J S Burchmore; Caroline Clucas; Christiane Hertz-Fowler; Karen Brooks; Andy Tait; Annette MacLeod; C Michael R Turner; Harry P De Koning; Pui Ee Wong; Michael P Barrett
Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes.
Eukaryotic cell 2010;9(2):336-43.
2009: Craig W Duffy; Liam J Morrison; Alana Black; Gina L Pinchbeck; Robert Christley; Andreas Schoenefeld; Andy Tait; C Michael R Turner; Annette MacLeod
Trypanosoma vivax displays a clonal population structure.
International journal for parasitology 2009;39(13):1475-83.
2009: Liam J Morrison; Andy Tait; Sarah McLellan; Lindsay Sweeney; C Michael R Turner; Annette MacLeod
A major genetic locus in Trypanosoma brucei is a determinant of host pathology.
PLoS neglected tropical diseases 2009;3(12):e557.
2009: Liam J Morrison; Alison Tweedie; Alana Black; Gina L Pinchbeck; Robert Christley; Andreas Schoenefeld; Christiane Hertz-Fowler; Annette MacLeod; C Michael R Turner; Andy Tait
Discovery of mating in the major African livestock pathogen Trypanosoma congolense.
PloS one 2009;4(5):e5564.
2008: Liam J Morrison; Andy Tait; Gillian McCormack; Lindsay Sweeney; Alana Black; Philippe Truc; Anne C L Likeufack; C Michael R Turner; Annette MacLeod
Trypanosoma brucei gambiense Type 1 populations from human patients are clonal and display geographical genetic differentiation.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2008;8(6):847-54.
2008: Francisca Mutapi; Richard J S Burchmore; Takafira MDULUZA; Nicholas Midzi; C Michael R Turner; Rick M Maizels
Age-related and infection intensity-related shifts in antibody recognition of defined protein antigens in a schistosome-exposed population.
The Journal of infectious diseases 2008;198(2):167-75.
2008: Anneli Cooper; Andy Tait; Lindsay Sweeney; Alison Tweedie; Liam Morrison; C Michael R Turner; Annette MacLeod
Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map.
Genome biology 2008;9(6):R103.
2007: Liam J Morrison; Gillian McCormack; Lindsay Sweeney; Anne C L Likeufack; Philippe Truc; C Michael R Turner; Andy Tait; Annette MacLeod
Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters.
The American journal of tropical medicine and hygiene 2007;76(6):1132-7.
2007: Andy Tait; Annette MacLeod; Alison Tweedie; Daniel K Masiga; C Michael R Turner
Genetic exchange in Trypanosoma brucei: evidence for mating prior to metacyclic stage development.
Molecular and biochemical parasitology 2007;151(1):133-6.
2006: Daniel K Masiga; Kariuki Ndung'u; Alison Tweedie; Andy Tait; C Michael R Turner
Trypanosoma evansi: genetic variability detected using amplified restriction fragment length polymorphism (AFLP) and random amplified polymorphic DNA (RAPD) analysis of Kenyan isolates.
Experimental parasitology 2006;114(3):147-53.
2006: Aude Lise Foucher; Anne McIntosh; Gill Douce; Jonathan Wastling; Andy Tait; C Michael R Turner
A proteomic analysis of arsenical drug resistance in Trypanosoma brucei.
Proteomics 2006;6(9):2726-32.
2006: Andrew Jones; Anne Faldas; Aude Lise Foucher; Ela Hunt; Andy Tait; Jonathan Wastling; C Michael R Turner
Visualisation and analysis of proteomic data from the procyclic form of Trypanosoma brucei.
Proteomics 2006;6(1):259-67.
2005: Francisca Mutapi; Richard J S Burchmore; Takafira MDULUZA; Aude Lise Foucher; Yvonne M Harcus; Gavin Nicoll; Nicholas Midzi; C Michael R Turner; Rick M Maizels
Praziquantel treatment of individuals exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens.
The Journal of infectious diseases 2005;192(6):1108-18.
2005: Annette MacLeod; Alison Tweedie; Sarah McLellan; Michelle Hope; Sonya Taylor; Anneli Cooper; Lindsay Sweeney; C Michael R Turner; Andy Tait
Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis.
Molecular and biochemical parasitology 2005;143(1):12-9.
2005: Neil Hall; Marianna Karras; J Dale Raine; Jane M Carlton; Taco W A Kooij; Matthew Berriman; Laurence Florens; Christoph S Janssen; Arnab Pain; George Christophides; Keith James; Kim Rutherford; Barbara Harris; David Harris; Carol Churcher; Michael A Quail; Doug Ormond; Jon Doggett; Holly Trueman; Jacqui Mendoza; Shelby L Bidwell; Marie-Adele Rajandream; Daniel J Carucci; John R Yates; Fotis C Kafatos; Chris J Janse; Bart Barrell; C Michael R Turner; Andrew P Waters; Robert E Sinden
A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses.
Science (New York, N.Y.) 2005;307(5706):82-6.
2005: Annette MacLeod; Alison Tweedie; Sarah McLellan; Sonya Taylor; Neil Hall; Matthew Berriman; Najib M El-Sayed; Michelle Hope; C Michael R Turner; Andy Tait
The genetic map and comparative analysis with the physical map of Trypanosoma brucei.
Nucleic acids research 2005;33(21):6688-93.
2004: C Michael R Turner; Sarah McLellan; L A G Lindergard; L Bisoni; Andy Tait; Annette MacLeod
Human infectivity trait in Trypanosoma brucei: stability, heritability and relationship to sra expression.
Parasitology 2004;129(Pt 4):445-54.
2004: Christoph S Janssen; R Stephen Phillips; C Michael R Turner; Michael P Barrett
Plasmodium interspersed repeats: the major multigene superfamily of malaria parasites.
Nucleic acids research 2004;32(19):5712-20.
2004: Daniel K Masiga; C Michael R Turner
Amplified (restriction) fragment length polymorphism (AFLP) analysis.
Methods in molecular biology (Clifton, N.J.) 2004;270():173-86.
2003: Takafira MDULUZA; Patricia D Ndhlovu; Nicholas Midzi; JT Scott; Francisca Mutapi; Charles Mary; P Couissinier-Paris; C Michael R Turner; Stephen K Chandiwana; M E J Woolhouse; Alain Dessein; Paul Hagan
Contrasting cellular responses in Schistosoma haematobium infected and exposed individuals from areas of high and low transmission in Zimbabwe.
Immunology letters 2003;88(3):249-56.
2002: I Boibessot; C Michael R Turner; David G Watson; E Goldie; G Connel; Anne McIntosh; M Helen Grant; Graham G Skellern
Metabolism and distribution of phenanthridine trypanocides in Trypanosoma brucei.
Acta tropica 2002;84(3):219-28.
2002: Christoph S Janssen; Michael P Barrett; C Michael R Turner; R Stephen Phillips
A large gene family for putative variant antigens shared by human and rodent malaria parasites.
Proceedings. Biological sciences / The Royal Society 2002;269(1489):431-6.
2002: C Michael R Turner
A perspective on clonal phenotypic (antigenic) variation in protozoan parasites.
Parasitology 2002;125 Suppl():S17-23.
2001: Richard J S Burchmore; Christoph S Janssen; C Michael R Turner
After the genome--where next?
Molecular and biochemical parasitology 2001;118(2):129-31.
2001: Annette MacLeod; C Michael R Turner; Andy Tait
The detection of geographical substructuring of Trypanosoma brucei populations by the analysis of minisatellite polymorphisms.
Parasitology 2001;123(Pt 5):475-82.
2001: JT Scott; C Michael R Turner; Francisca Mutapi; M E J Woolhouse; Patricia D Ndhlovu; Paul Hagan
Cytokine responses to mitogen and Schistosoma haematobium antigens are different in children with distinct infection histories.
Parasite immunology 2001;23(10):519-26.
2001: Annette MacLeod; Andy Tait; C Michael R Turner
The population genetics of Trypanosoma brucei and the origin of human infectivity.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1411):1035-44.
2001: Douglas J LaCount; Najib M El-Sayed; S Kaul; D Wanless; C Michael R Turner; John E Donelson
Analysis of a donor gene region for a variant surface glycoprotein and its expression site in African trypanosomes.
Nucleic acids research 2001;29(10):2012-9.
2001: Christoph S Janssen; Michael P Barrett; Daniel Lawson; Michael A Quail; David Harris; Sharen Bowman; R Stephen Phillips; C Michael R Turner
Gene discovery in Plasmodium chabaudi by genome survey sequencing.
Molecular and biochemical parasitology 2001;113(2):251-60.
2001: Annette MacLeod; Susan C Welburn; Ian Maudlin; C Michael R Turner; Andy Tait
Evidence for multiple origins of human infectivity in Trypanosoma brucei revealed by minisatellite variant repeat mapping.
Journal of molecular evolution 2001;52(3):290-301.
2001: Takafira MDULUZA; Patricia D Ndhlovu; T M Madziwa; Nicholas Midzi; RB Zinyama; C Michael R Turner; Stephen K Chandiwana; Norman Nyazema; Paul Hagan
The impact of repeated treatment with praziquantel of schistosomiasis in children under six years of age living in an endemic area for Schistosoma haematobium infection.
Memórias do Instituto Oswaldo Cruz 2001;96 Suppl():157-64.
2001: Takafira MDULUZA; Patricia D Ndhlovu; Nicholas Midzi; Charles Mary; C P Paris; C Michael R Turner; Stephen K Chandiwana; M E J Woolhouse; Alain Dessein; Paul Hagan
T cell clones from Schistosoma haematobium infected and exposed individuals lacking distinct cytokine profiles for Th1/Th2 polarisation.
Memórias do Instituto Oswaldo Cruz 2001;96 Suppl():89-101.
2000: Annette MacLeod; Alison Tweedie; Susan C Welburn; Ian Maudlin; C Michael R Turner; Andy Tait
Minisatellite marker analysis of Trypanosoma brucei: reconciliation of clonal, panmictic, and epidemic population genetic structures.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13442-7.
2000: Daniel K Masiga; Andy Tait; C Michael R Turner
Amplified restriction fragment length polymorphism in parasite genetics.
Parasitology today (Personal ed.) 2000;16(8):350-3.
1999: Michelle Hope; Annette MacLeod; Vanessa Leech; Sara E Melville; J Sasse; Andy Tait; C Michael R Turner
Analysis of ploidy (in megabase chromosomes) in Trypanosoma brucei after genetic exchange.
Molecular and biochemical parasitology 1999;104(1):1-9.
1999: C Michael R Turner
Antigenic variation in Trypanosoma brucei infections: an holistic view.
Journal of cell science 1999;112 ( Pt 19)():3187-92.
1999: Annette MacLeod; C Michael R Turner; Andy Tait
A high level of mixed Trypanosoma brucei infections in tsetse flies detected by three hypervariable minisatellites.
Molecular and biochemical parasitology 1999;102(2):237-48.
1999: A E Millar; J Sternberg; Charles P McSharry; Xiao-Qing Wei; Foo Y Liew; C Michael R Turner
T-Cell responses during Trypanosoma brucei infections in mice deficient in inducible nitric oxide synthase.
Infection and immunity 1999;67(7):3334-8.
1998: Francisca Mutapi; Patricia D Ndhlovu; Paul Hagan; J T Spicer; Takafira MDULUZA; C Michael R Turner; Stephen K Chandiwana; M E J Woolhouse
Chemotherapy accelerates the development of acquired immune responses to Schistosoma haematobium infection.
The Journal of infectious diseases 1998;178(1):289-93.
1997: C Michael R Turner
The rate of antigenic variation in fly-transmitted and syringe-passaged infections of Trypanosoma brucei.
FEMS microbiology letters 1997;153(1):227-31.
1997: C Michael R Turner
Trypanosomes with multicoloured coats.
Parasitology today (Personal ed.) 1997;13(7):247-8.
1997: A G Scott; Andy Tait; C Michael R Turner
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
Experimental parasitology 1997;86(3):181-90.
1997: Annette MacLeod; C Michael R Turner; Andy Tait
Detection of single copy gene sequences from single trypanosomes.
Molecular and biochemical parasitology 1997;84(2):267-70.
1997: C Michael R Turner; Sara E Melville; Andy Tait
A proposal for karyotype nomenclature in Trypanosoma brucei.
Parasitology today (Personal ed.) 1997;13(1):5-6.
1996: Andy Tait; N Buchanan; Geoff Hide; C Michael R Turner
Self-fertilisation in Trypanosoma brucei.
Molecular and biochemical parasitology 1996;76(1-2):31-42.
1996: A G Scott; Andy Tait; C Michael R Turner
Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin.
Acta tropica 1996;60(4):251-62.
1996: C Michael R Turner; N Aslam; S D Angus
Inhibition of growth of Trypanosoma brucei parasites in chronic infections.
Parasitology research 1996;82(1):61-6.
1995: C Michael R Turner; N Aslam; C Dye
Replication, differentiation, growth and the virulence of Trypanosoma brucei infections.
Parasitology 1995;111 ( Pt 3)():289-300.
1995: C Michael R Turner; Geoff Hide; N Buchanan; Andy Tait
Trypanosoma brucei: inheritance of kinetoplast DNA maxicircles in a genetic cross and their segregation during vegetative growth.
Experimental parasitology 1995;80(2):234-41.
1994: L R Brannan; C Michael R Turner; R Stephen Phillips
Malaria parasites undergo antigenic variation at high rates in vivo.
Proceedings. Biological sciences / The Royal Society 1994;256(1345):71-5.
1993: L M McLintock; C Michael R Turner; Keith Vickerman
Comparison of the effects of immune killing mechanisms on Trypanosoma brucei parasites of slender and stumpy morphology.
Parasite immunology 1993;15(8):475-80.
1992: C Michael R Turner
Cell cycle co-ordination in trypanosomes.
Parasitology today (Personal ed.) 1992;8(1):3-4.
1992: N Aslam; C Michael R Turner
The relationship of variable antigen expression and population growth rates in Trypanosoma brucei.
Parasitology research 1992;78(8):661-4.
1991: C Michael R Turner; N Aslam; E Smith; N Buchanan; Andy Tait
The effects of genetic exchange on variable antigen expression in Trypanosoma brucei.
Parasitology 1991;103 Pt 3():379-86.
1991: J David Barry; C Michael R Turner
The dynamics of antigenic variation and growth of African trypanosomes.
Parasitology today (Personal ed.) 1991;7(8):207-11.
1990: C Michael R Turner; J Sternberg; N Buchanan; E Smith; Geoff Hide; Andy Tait
Evidence that the mechanism of gene exchange in Trypanosoma brucei involves meiosis and syngamy.
Parasitology 1990;101 Pt 3():377-86.
1990: L M McLintock; C Michael R Turner; Keith Vickerman
A comparison of multiplication rates in primary and challenge infections of Trypanosoma brucei bloodstream forms.
Parasitology 1990;101 Pt 1():49-55.
1990: Andy Tait; C Michael R Turner
Genetic exchange in Trypanosoma brucei.
Parasitology today (Personal ed.) 1990;6(3):70-5.
1990: C Michael R Turner
The use of experimental artefacts in African trypanosome research.
Parasitology today (Personal ed.) 1990;6(1):14-7.
1989: Andy Tait; C Michael R Turner; Richard Le Page; Jerry M Wells
Genetic evidence that metacyclic forms of Trypanosoma brucei are diploid.
Molecular and biochemical parasitology 1989;37(2):247-55.
1989: C Michael R Turner; J David Barry
High frequency of antigenic variation in Trypanosoma brucei rhodesiense infections.
Parasitology 1989;99 Pt 1():67-75.
1989: J Sternberg; C Michael R Turner; Jerry M Wells; Lisa Ranford-Cartwright; Richard Le Page; Andy Tait
Gene exchange in African trypanosomes: frequency and allelic segregation.
Molecular and biochemical parasitology 1989;34(3):269-79.
1989: C Michael R Turner; M Menrath; Andy Tait
Life-cycle-stage- and stock-specific labelling by monoclonal antibodies of Trypanosoma brucei procyclic forms.
Parasitology research 1989;75(5):414-5.
1988: C Michael R Turner
Trypanosome vaccines.
Parasitology today (Personal ed.) 1988;4(12):360.
1988: C Michael R Turner; J David Barry; Ian Maudlin; Keith Vickerman
An estimate of the size of the metacyclic variable antigen repertoire of Trypanosoma brucei rhodesiense.
Parasitology 1988;97 ( Pt 2)():269-76.
1988: C Michael R Turner; J David Barry; Keith Vickerman
Loss of variable antigen during transformation of Trypanosoma brucei rhodesiense from bloodstream to procyclic forms in the tsetse fly.
Parasitology research 1988;74(6):507-11.
1988: Keith Vickerman; Laurence Tetley; K A Hendry; C Michael R Turner
Biology of African trypanosomes in the tsetse fly.
Biology of the cell / under the auspices of the European Cell Biology Organization 1988;64(2):109-19.
1987: Laurence Tetley; C Michael R Turner; J David Barry; J S Crowe; Keith Vickerman
Onset of expression of the variant surface glycoproteins of Trypanosoma brucei in the tsetse fly studied using immunoelectron microscopy.
Journal of cell science 1987;87 ( Pt 2)():363-72.
1986: C Michael R Turner; J David Barry; Keith Vickerman
Independent expression of the metacyclic and bloodstream variable antigen repertoires of Trypanosoma brucei rhodesiense.
Parasitology 1986;92 ( Pt 1)():67-73.
1986: C Michael R Turner; C A Hunter; J David Barry; Keith Vickerman
Similarity in variable antigen type composition of Trypanosoma brucei rhodesiense populations in different sites within the mouse host.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1986;80(5):824-30.