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Nicholas Turner

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Publications

TOP 3
Nicholas J Turner; Elaine O'Reilly
Biocatalytic retrosynthesis.
Nicholas J Turner; Matthew D Truppo
Biocatalysis enters a new era.
Elaine O'Reilly; Nicholas J Turner; Suzanne J Aitken; Gideon Grogan; Paul P Kelly; Sabine L Flitsch
Regio- and stereoselective oxidation of unactivated C-H bonds with Rhodococcus rhodochrous.

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All Publications

2013: Nicholas J Turner; Elaine O'Reilly
Biocatalytic retrosynthesis.
Nature chemical biology 2013;9(5):285-8.
2013: Nicholas J Turner; Matthew D Truppo
Biocatalysis enters a new era.
Current opinion in chemical biology 2013;17(2):212-4.
2012: Elaine O'Reilly; Nicholas J Turner; Suzanne J Aitken; Gideon Grogan; Paul P Kelly; Sabine L Flitsch
Regio- and stereoselective oxidation of unactivated C-H bonds with Rhodococcus rhodochrous.
Beilstein journal of organic chemistry 2012;8():496-500.
2011: Colin J Dunsmore; Kirk J Malone; Kevin R Bailey; Martin A Wear; Hannah Florance; Sally Shirran; Perdita E Barran; Antony P Page; Malcolm D Walkinshaw; Nicholas J Turner
Design and synthesis of conformationally constrained cyclophilin inhibitors showing a cyclosporin-A phenotype in C. elegans.
Chembiochem : a European journal of chemical biology 2011;12(5):802-10.
2008: Matthew W Nowicki; Lindsay B Tulloch; Liam Worralll; Iain W McNae; Véronique Hannaert; Paul A M Michels; Linda A Fothergill-Gilmore; Malcolm D Walkinshaw; Nicholas J Turner
Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis.
Bioorganic & medicinal chemistry 2008;16(9):5050-61.
2007: Yuande Yang; Elizabeth Moir; George Kontopidis; Paul Taylor; Martin A Wear; Kirk Malone; Colin J Dunsmore; Antony P Page; Nicholas J Turner; Malcolm D Walkinshaw
Structure-based discovery of a family of synthetic cyclophilin inhibitors showing a cyclosporin-A phenotype in Caenorhabditis elegans.
Biochemical and biophysical research communications 2007;363(4):1013-9.
2007: Tom S C Eve; Andrew Wells; Nicholas J Turner
Enantioselective oxidation of O-methyl-N-hydroxylamines using monoamine oxidase N as catalyst.
Chemical communications (Cambridge, England) 2007;(15):1530-1.
2006: Ayhan Celik; Gareth A Roberts; John H White; Stephen K Chapman; Nicholas J Turner; Sabine L Flitsch
Probing the substrate specificity of the catalytically self-sufficient cytochrome P450 RhF from a Rhodococcus sp.
Chemical communications (Cambridge, England) 2006;(43):4492-4.
2006: I Fotheringham; I Archer; Reuben Carr; Robert E Speight; Nicholas J Turner
Preparative deracemization of unnatural amino acids.
Biochemical Society transactions 2006;34(Pt 2):287-90.
2006: Colin J Dunsmore; Reuben Carr; Toni Fleming; Nicholas J Turner
A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines.
Journal of the American Chemical Society 2006;128(7):2224-5.
2005: Martin A Wear; Alan Patterson; Kirk Malone; Colin J Dunsmore; Nicholas J Turner; Malcolm D Walkinshaw
A surface plasmon resonance-based assay for small molecule inhibitors of human cyclophilin A.
Analytical biochemistry 2005;345(2):214-26.
2005: Ayhan Celik; Sabine L Flitsch; Nicholas J Turner
Efficient terpene hydroxylation catalysts based upon P450 enzymes derived from actinomycetes.
Organic & biomolecular chemistry 2005;3(16):2930-4.
2005: Ayhan Celik; Davide Sperandio; Robert E Speight; Nicholas J Turner
Enantioselective epoxidation of linolenic acid catalysed by cytochrome P450(BM3) from Bacillus megaterium.
Organic & biomolecular chemistry 2005;3(15):2688-90.
2005: Ayhan Celik; Robert E Speight; Nicholas J Turner
Identification of broad specificity P450CAM variants by primary screening against indole as substrate.
Chemical communications (Cambridge, England) 2005;(29):3652-4.
2005: Dominic J B Hunter; Gareth A Roberts; Tobias W B Ost; John H White; Steffen Müller; Nicholas J Turner; Sabine L Flitsch; Stephen K Chapman
Analysis of the domain properties of the novel cytochrome P450 RhF.
FEBS letters 2005;579(10):2215-20.
2005: Reuben Carr; Marina Alexeeva; Michael J Dawson; Vicente Gotor-Fernández; Cara E Humphrey; Nicholas J Turner
Directed evolution of an amine oxidase for the preparative deracemisation of cyclic secondary amines.
Chembiochem : a European journal of chemical biology 2005;6(4):637-9.
2005: Rajamohan R Poondra; Nicholas J Turner
Microwave-assisted sequential amide bond formation and intramolecular amidation: a rapid entry to functionalized oxindoles.
Organic letters 2005;7(5):863-6.
2004: Rajamohan R Poondra; Peter M Fischer; Nicholas J Turner
Efficient palladium-catalyzed cross-coupling of beta-chloroalkylidene/arylidene malonates using microwave chemistry.
The Journal of organic chemistry 2004;69(20):6920-2.
2004: Cara E Humphrey; Morag A M Easson; Nicholas J Turner
Dimedone esters as novel hydrolase substrates and their application in the colorimetric detection of lipase and esterase activity.
Chembiochem : a European journal of chemical biology 2004;5(8):1144-8.
2004: Geoffrey J Roff; Richard C Lloyd; Nicholas J Turner
A versatile chemo-enzymatic route to enantiomerically pure beta-branched alpha-amino acids.
Journal of the American Chemical Society 2004;126(13):4098-9.
2004: Gareth A Roberts; Gideon Grogan; Nicholas J Turner; Sabine L Flitsch
Nucleotide sequence of a portion of the camphor-degrading gene cluster from Rhodococcus sp. NCIMB 9784.
DNA sequence : the journal of DNA sequencing and mapping 2004;15(2):96-103.
2004: Nicholas J Turner
Enzyme catalysed deracemisation and dynamic kinetic resolution reactions.
Current opinion in chemical biology 2004;8(2):114-9.
2003: Marina Alexeeva; Reuben Carr; Nicholas J Turner
Directed evolution of enzymes: new biocatalysts for asymmetric synthesis.
Organic & biomolecular chemistry 2003;1(23):4133-7.
2003: Gareth A Roberts; Ayhan Celik; Dominic J B Hunter; Tobias W B Ost; John H White; Stephen K Chapman; Nicholas J Turner; Sabine L Flitsch
A self-sufficient cytochrome p450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox center.
The Journal of biological chemistry 2003;278(49):48914-20.
2003: Cara E Humphrey; Nicholas J Turner; Morag A M Easson; Sabine L Flitsch; Rein V Ulijn
Lipase-catalyzed kinetic resolution on solid-phase via a "capture and release" strategy.
Journal of the American Chemical Society 2003;125(46):13952-3.
2003: Nicholas J Turner
Directed evolution of enzymes for applied biocatalysis.
Trends in biotechnology 2003;21(11):474-8.
2003: Alexis Enright; Francois-Rene Alexandre; Geoffrey Roff; Ian G Fotheringham; Michael J Dawson; Nicholas J Turner
Stereoinversion of beta- and gamma-substituted alpha-amino acids using a chemo-enzymatic oxidation-reduction procedure.
Chemical communications (Cambridge, England) 2003;(20):2636-7.
2003: Reuben Carr; Marina Alexeeva; Alexis Enright; Tom S C Eve; Michael J Dawson; Nicholas J Turner
Directed evolution of an amine oxidase possessing both broad substrate specificity and high enantioselectivity.
Angewandte Chemie (International ed. in English) 2003;42(39):4807-10.
2003: Nicholas J Turner
Controlling chirality.
Current opinion in biotechnology 2003;14(4):401-6.
2003: Cara E Humphrey; Morag A M Easson; Jason P Tierney; Nicholas J Turner
Solid-supported cyclohexane-1,3-dione (CHD): a "capture and release" reagent for the synthesis of amides and novel scavenger resin.
Organic letters 2003;5(6):849-52.
2002: Roger J Lins; Sabine L Flitsch; Nicholas J Turner; Ed Irving; Stuart A Brown
Enzymatic generation and in situ screening of a dynamic combinatorial library of sialic acid analogues.
Angewandte Chemie (International ed. in English) 2002;41(18):3405-7.
2002: Marina Alexeeva; Alexis Enright; Michael J Dawson; Mahmoud Mahmoudian; Nicholas J Turner
Deracemization of alpha-methylbenzylamine using an enzyme obtained by in vitro evolution.
Angewandte Chemie (International ed. in English) 2002;41(17):3177-80.
2002: Gideon Grogan; Gareth A Roberts; S Parsons; Nicholas J Turner; Sabine L Flitsch
P450(camr), a cytochrome P450 catalysing the stereospecific 6- endo-hydroxylation of (1 R)-(+)-camphor.
Applied microbiology and biotechnology 2002;59(4-5):449-54.
2002: Gareth A Roberts; Gideon Grogan; Andy Greter; Sabine L Flitsch; Nicholas J Turner
Identification of a new class of cytochrome P450 from a Rhodococcus sp.
Journal of bacteriology 2002;184(14):3898-908.
2002: Timothy M Beard; Nicholas J Turner
Deracemisation and stereoinversion of alpha-amino acids using D-amino acid oxidase and hydride reducing agents.
Chemical communications (Cambridge, England) 2002;(3):246-7.
2002: Tony Cass; Jim Dunwell; Lawrence P Wackett; Gianfranco Gilardi; Thomas A Kost; Patrick Condreay; Steven Projan; Jeroen Hugenholtz; Michiel Kleerebezem; Nicholas J Turner; Robert E Speight
Biotechnology. Paper Alert.
Current opinion in biotechnology 2002;13(1):1-8.
2001: Gideon Grogan; Gareth A Roberts; D Bougioukou; Nicholas J Turner; Sabine L Flitsch
The desymmetrization of bicyclic beta -diketones by an enzymatic retro-Claisen reaction. A new reaction of the crotonase superfamily.
The Journal of biological chemistry 2001;276(16):12565-72.
2000: Nicholas J Turner
Applications of transketolases in organic synthesis.
Current opinion in biotechnology 2000;11(6):527-31.
1999: Paul Taylor; V Anderson; J Dowden; Sabine L Flitsch; Nicholas J Turner; K Loughran; Malcolm D Walkinshaw
Novel mechanism of inhibition of elastase by beta-lactams is defined by two inhibitor crystal complexes.
The Journal of biological chemistry 1999;274(35):24901-5.