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Thomas Tuschl

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Chemicals & Drugs

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Marianna Teplova; Thomas Tuschl; Katharina Essig; Markus Hafner; Dmitri Teplov; Dinshaw J Patel
Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Hana Totary-Jain; Thomas Tuschl; Steven O Marx; Despina Sanoudou; Iddo Z Ben-Dov; Cula N Dautriche; Paolo Guarnieri; Andrew R Marks
Reprogramming of the microRNA transcriptome mediates resistance to rapamycin.
Manuel Ascano; Stefanie Gerstberger; Thomas Tuschl
Multi-disciplinary methods to define RNA-protein interactions and regulatory networks.

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2013: Marianna Teplova; Thomas Tuschl; Katharina Essig; Markus Hafner; Dmitri Teplov; Dinshaw J Patel
Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Genes & development 2013;27(8):928-40.
2013: Hana Totary-Jain; Thomas Tuschl; Steven O Marx; Despina Sanoudou; Iddo Z Ben-Dov; Cula N Dautriche; Paolo Guarnieri; Andrew R Marks
Reprogramming of the microRNA transcriptome mediates resistance to rapamycin.
The Journal of biological chemistry 2013;288(9):6034-44.
2013: Manuel Ascano; Stefanie Gerstberger; Thomas Tuschl
Multi-disciplinary methods to define RNA-protein interactions and regulatory networks.
Current opinion in genetics & development 2013;23(1):20-8.
2013: Thalia A Farazi; Jessica I Hoell; Pavel Morozov; Thomas Tuschl
MicroRNAs in human cancer.
Advances in experimental medicine and biology 2013;774():1-20.
2012: Manuel Ascano; Pradeep Bandaru; David L Corcoran; Scott Dewell; Markus Hafner; Christine Langlois; Jason B Miller; Neelanjan Mukherjee; Mathias Munschauer; Jeffrey D Nusbaum; Uwe Ohler; Zev Williams; Thomas Tuschl
FMRP targets distinct mRNA sequence elements to regulate protein expression.
Nature 2012;492(7429):382-6.
2012: Iddo Z Ben-Dov; Pavel Morozov; Franco B Mueller; Thangamani Muthukumar; Thomas Tuschl; Manikkam Suthanthiran
MicroRNA sequence profiles of human kidney allografts with or without tubulointerstitial fibrosis.
Transplantation 2012;94(11):1086-94.
2012: Markus Hafner; Steve Lianoglou; Thomas Tuschl; Doron Betel
Genome-wide identification of miRNA targets by PAR-CLIP.
Methods (San Diego, Calif.) 2012;58(2):94-105.
2012: Markus Hafner; Aleksandra Mihailović; John T G Pena; Neil Renwick; Thalia A Farazi; Thomas Tuschl
Barcoded cDNA library preparation for small RNA profiling by next-generation sequencing.
Methods (San Diego, Calif.) 2012;58(2):164-70.
2012: Marion Scheibe; Thomas Tuschl; Falk Butter; Markus Hafner; Matthias Mann
Quantitative mass spectrometry and PAR-CLIP to identify RNA-protein interactions.
Nucleic acids research 2012;40(19):9897-902.
2012: Thalia A Farazi; Markus Hafner; Volker Hovestadt; Aleksandra Mihailović; Pavel Morozov; Neil Renwick; Jelle J Ten Hoeve; Iddo Z Ben-Dov; Miguel Brown; Lodewyk F A Wessels; Thomas Tuschl
Bioinformatic analysis of barcoded cDNA libraries for small RNA profiling by next-generation sequencing.
Methods (San Diego, Calif.) 2012;58(2):171-87.
2012: Priyamvada Rajasethupathy; Chris Sander; Robert Sheridan; Thomas Tuschl; Igor Antonov; Sebastian Frey; Eric R Kandel
A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity.
Cell 2012;149(3):693-707.
2012: Stefan Juranek; Yael Altuvia; Miguel Brown; Tali Eban; Pavel Morozov; Thomas Tuschl; Hanah Margalit
A genome-wide view of the expression and processing patterns of Thermus thermophilus HB8 CRISPR RNAs.
RNA (New York, N.Y.) 2012;18(4):783-94.
2012: Manuel Ascano; Pavol Cekan; Stefanie Gerstberger; Markus Hafner; Thomas Tuschl
Identification of RNA-protein interaction networks using PAR-CLIP.
Wiley interdisciplinary reviews. RNA 2012;3(2):159-77.
2012: Rebecca L Skalsky; Thomas Tuschl; David L Corcoran; Henri-Jacques Delecluse; Regina Feederle; Christopher L Frank; Eva Gottwein; Markus Hafner; Dong Kang; Micah Luftig; Jeffrey D Nusbaum; Uwe Ohler; Bryan R Cullen
The viral and cellular microRNA targetome in lymphoblastoid cell lines.
PLoS pathogens 2012;8(1):e1002484.
2011: Markus Hafner; Manuel Ascano; Thomas Tuschl
New insights in the mechanism of microRNA-mediated target repression.
Nature structural & molecular biology 2011;18(11):1181-2.
2011: Inna Lipchina; Aleksandra Mihailovic; Chris Sander; Robert Sheridan; Studer Lorenz; Thomas Tuschl; Yechiel Elkabetz; Markus Hafner; Doron Betel
Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response.
Genes & development 2011;25(20):2173-86.
2011: Markus Hafner; Daniel Holoch; Carolina Lin; Janos Ludwig; Shujun Luo; Pavel Morozov; Jeffrey D Nusbaum; Tolulope Ojo; John T G Pena; Neil Renwick; Gary Schroth; Miguel Brown; Aleksandra Mihailović; Thomas Tuschl
RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries.
RNA (New York, N.Y.) 2011;17(9):1697-712.
2011: Neelanjan Mukherjee; Jeffrey D Nusbaum; Uwe Ohler; David W Reid; Thomas Tuschl; Manuel Ascano; David L Corcoran; Stoyan Georgiev; Markus Hafner; Jack D Keene
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.
Molecular cell 2011;43(3):327-39.
2011: Thalia A Farazi; Markus Hafner; Hans Halfwerk; Hugo M Horlings; Volker Hovestadt; Bas Kreike; Aleksandra Mihailovic; Pavel Morozov; Fabien Reyal; Daoud Sie; Jelle J Ten Hoeve; Marc J van de Vijver; Marieke van Kouwenhove; Lodewyk F A Wessels; Miguel Brown; Thomas Tuschl
MicroRNA sequence and expression analysis in breast tumors by deep sequencing.
Cancer research 2011;71(13):4443-53.
2011: Huan Wang; Jongchan Woo; Xiuren Zhang; Nam-Hai Chua; Markus Hafner; Takatoshi Kiba; Jun Liu; Tolulope Ojo; Thomas Tuschl; Xiu-Jie Wang
Deep sequencing of small RNAs specifically associated with Arabidopsis AGO1 and AGO4 uncovers new AGO functions.
The Plant journal : for cell and molecular biology 2011;67(2):292-304.
2011: Yuan Tian; Dhirendra K Simanshu; Manuel Ascano; Ruben Diaz-Avalos; Ah Young Park; Stefan A Juranek; William J Rice; Qian Yin; Carol V Robinson; Thomas Tuschl; Dinshaw J Patel
Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex.
Nature structural & molecular biology 2011;18(6):658-64.
2011: Thalia A Farazi; Jessica I Spitzer; Pavel Morozov; Thomas Tuschl
miRNAs in human cancer.
The Journal of pathology 2011;223(2):102-15.
2010: Yanli Wang; Janos Ludwig; Christine Schuberth; Marion Goldeck; Martin Schlee; Haitao Li; Stefan Juranek; Gang Sheng; Ronald Micura; Thomas Tuschl; Gunther Hartmann; Dinshaw J Patel
Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
Nature structural & molecular biology 2010;17(7):781-7.
2010: Markus Hafner; Markus Landthaler; Lukas Burger; Mohsen Khorshid; Jean Hausser; Philipp Berninger; Andrea Rothballer; Manuel Ascano; Anna-Carina Jungkamp; Mathias Munschauer; Alexander Ulrich; Greg S Wardle; Scott Dewell; Mihaela Zavolan; Thomas Tuschl
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.
Cell 2010;141(1):129-41.
2010: Markus Hafner; Markus Landthaler; Lukas Burger; Mohsen Khorshid; Jean Hausser; Philipp Berninger; Andrea Rothballer; Manuel Ascano; Anna-Carina Jungkamp; Mathias Munschauer; Alexander Ulrich; Greg S Wardle; Scott Dewell; Mihaela Zavolan; Thomas Tuschl
PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins.
Journal of visualized experiments : JoVE 2010;(41):.
2009: Yanli Wang; Stefan Juranek; Haitao Li; Gang Sheng; Greg S Wardle; Thomas Tuschl; Dinshaw J Patel
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature 2009;461(7265):754-61.
2009: Priyamvada Rajasethupathy; Ferdinando Fiumara; Robert Sheridan; Doron Betel; Sathyanarayanan V Puthanveettil; James J Russo; Chris Sander; Thomas Tuschl; Eric R Kandel
Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.
Neuron 2009;63(6):803-17.
2009: Jason Huse; Cameron Brennan; Dolares Hambardzumyan; Boyoung Wee; John Pena; Sara H Rouhanifard; Cherin Sohn-Lee; Carlos le Sage; Reuven Agami; Thomas Tuschl; Eric C Holland
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo.
Genes & development 2009;23(11):1327-37.
2009: John T G Pena; Cherin Sohn-Lee; Sara H Rouhanifard; Janos Ludwig; Markus Hafner; Aleksandra Mihailovic; Cindy Lim; Daniel Holoch; Philipp Berninger; Mihaela Zavolan; Thomas Tuschl
miRNA in situ hybridization in formaldehyde and EDC-fixed tissues.
Nature methods 2009;6(2):139-41.
2009: Rui Yi; H Amalia Pasolli; Markus Landthaler; Markus Hafner; Tolulope Ojo; Robert Sheridan; Chris Sander; Dónal O'Carroll; Markus Stoffel; Thomas Tuschl; Elaine Fuchs
DGCR8-dependent microRNA biogenesis is essential for skin development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):498-502.
2008: Yanli Wang; Gang Sheng; Stefan Juranek; Thomas Tuschl; Dinshaw J Patel
Structure of the guide-strand-containing argonaute silencing complex.
Nature 2008;456(7219):209-13.
2008: Grace Teng; Paul Hakimpour; Pablo Landgraf; Amanda Rice; Thomas Tuschl; Rafael Casellas; F Nina Papavasiliou
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase.
Immunity 2008;28(5):621-9.
2008: Thalia A Farazi; Stefan A Juranek; Thomas Tuschl
The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members.
Development (Cambridge, England) 2008;135(7):1201-14.
2008: Po Yu Chen; Lasse Weinmann; Dimos Gaidatzis; Yi Pei; Mihaela Zavolan; Thomas Tuschl; Gunter Meister
Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity.
RNA (New York, N.Y.) 2008;14(2):263-74.
2008: Markus Hafner; Pablo Landgraf; Janos Ludwig; Amanda Rice; Tolulope Ojo; Carolina Lin; Daniel Holoch; Cindy Lim; Thomas Tuschl
Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing.
Methods (San Diego, Calif.) 2008;44(1):3-12.
2007: Jingdong Ye; Christofer D Barth; Potluri S R Anjaneyulu; Thomas Tuschl; Joseph A Piccirilli
Reactions of phosphate and phosphorothiolate diesters with nucleophiles: comparison of transition state structures.
Organic & biomolecular chemistry 2007;5(15):2491-7.
2007: Glenn Randall; Maryline Panis; Jacob D Cooper; Timothy L Tellinghuisen; Karen E Sukhodolets; Sébastien Pfeffer; Markus Landthaler; Pablo Landgraf; Sherry Kan; Brett D Lindenbach; Minchen Chien; David B Weir; James J Russo; Jingyue Ju; Michael J Brownstein; Robert Sheridan; Chris Sander; Mihaela Zavolan; Thomas Tuschl; Charles M Rice
Cellular cofactors affecting hepatitis C virus infection and replication.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12884-9.
2007: Valerio Fulci; Sabina Chiaretti; Marina Goldoni; Gianluca Azzalin; Nicoletta Carucci; Simona Tavolaro; Leandro Castellano; Armando Magrelli; Franca Citarella; Monica Messina; Roberta Maggio; Nadia Peragine; Simona Santangelo; Francesca Romana Mauro; Pablo Landgraf; Thomas Tuschl; David B Weir; Minchen Chien; James J Russo; Jingyue Ju; Robert Sheridan; Chris Sander; Mihaela Zavolan; Anna Guarini; Robin Foà; Giuseppe Macino
Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia.
Blood 2007;109(11):4944-51.
2007: Mikhail S Klenov; Sergey Lavrov; Anastasia D Stolyarenko; Sergey S Ryazansky; Alexei A Aravin; Thomas Tuschl; Vladimir A Gvozdev
Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline.
Nucleic acids research 2007;35(16):5430-8.
2007: Jan Krützfeldt; Satoru Kuwajima; Ravi Braich; Kallanthottathil G Rajeev; John Pena; Thomas Tuschl; Muthiah Manoharan; Markus Stoffel
Specificity, duplex degradation and subcellular localization of antagomirs.
Nucleic acids research 2007;35(9):2885-92.
2006: Xiuren Zhang; Yu-Ren Yuan; Yi Pei; Shih-Shun Lin; Thomas Tuschl; Dinshaw J Patel; Nam-Hai Chua
Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense.
Genes & development 2006;20(23):3255-68.
2006: Yu-Ren Yuan; Yi Pei; Hong-Ying Chen; Thomas Tuschl; Dinshaw J Patel
A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.
Structure (London, England : 1993) 2006;14(10):1557-65.
2006: Yi Pei; Thomas Tuschl
On the art of identifying effective and specific siRNAs.
Nature methods 2006;3(9):670-6.
2006: Alexei A Aravin; Dimos Gaidatzis; Sébastien Pfeffer; Mariana Lagos-Quintana; Pablo Landgraf; Nicola Iovino; Patricia Morris; Michael J Brownstein; Satomi Kuramochi-Miyagawa; Toru Nakano; Minchen Chien; James J Russo; Jingyue Ju; Robert Sheridan; Chris Sander; Mihaela Zavolan; Thomas Tuschl
A novel class of small RNAs bind to MILI protein in mouse testes.
Nature 2006;442(7099):203-7.
2006: Markus Hossbach; Jens Gruber; Mary Osborn; Klaus Weber; Thomas Tuschl
Gene silencing with siRNA duplexes composed of target-mRNA-complementary and partially palindromic or partially complementary single-stranded siRNAs.
RNA biology 2006;3(2):82-9.
2006: Dinshaw J Patel; Jin-Biao Ma; Yu-Ren Yuan; Keqiong Ye; Yi Pei; Vitaly Kuryavyi; Lucy Malinina; Gunter Meister; Thomas Tuschl
Structural biology of RNA silencing and its functional implications.
Cold Spring Harbor symposia on quantitative biology 2006;71():81-93.
2005: Gunter Meister; Markus Landthaler; Lasse Peters; Po Yu Chen; Henning Urlaub; Reinhard Lührmann; Thomas Tuschl
Identification of novel argonaute-associated proteins.
Current biology : CB 2005;15(23):2149-55.
2005: Jan Krützfeldt; Nikolaus Rajewsky; Ravi Braich; Kallanthottathil G Rajeev; Thomas Tuschl; Muthiah Manoharan; Markus Stoffel
Silencing of microRNAs in vivo with 'antagomirs'.
Nature 2005;438(7068):685-9.
2005: Sébastien Pfeffer; Mariana Lagos-Quintana; Thomas Tuschl
Cloning of small RNA molecules.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2005;Chapter 26():Unit 26.4.
2005: Alexei A Aravin; Thomas Tuschl
Identification and characterization of small RNAs involved in RNA silencing.
FEBS letters 2005;579(26):5830-40.
2005: Yu-Ren Yuan; Yi Pei; Jin-Biao Ma; Vitaly Kuryavyi; Maria Zhadina; Gunter Meister; Hong-Ying Chen; Zbigniew Dauter; Thomas Tuschl; Dinshaw J Patel
Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage.
Molecular cell 2005;19(3):405-19.
2005: Jens Gruber; Heiko Manninga; Thomas Tuschl; Mary Osborn; Klaus Weber
Specific RNAi mediated gene knockdown in zebrafish cell lines.
RNA biology 2005;2(3):101-5.
2005: Dan Leaman; Po Yu Chen; John Fak; Abdullah Yalcin; Michael Pearce; Ulrich Unnerstall; Debora S Marks; Chris Sander; Thomas Tuschl; Ulrike Gaul
Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development.
Cell 2005;121(7):1097-108.
2005: Po Yu Chen; Heiko Manninga; Krasimir Slanchev; Minchen Chien; James J Russo; Jingyue Ju; Robert Sheridan; Bino John; Debora S Marks; Dimos Gaidatzis; Chris Sander; Mihaela Zavolan; Thomas Tuschl
The developmental miRNA profiles of zebrafish as determined by small RNA cloning.
Genes & development 2005;19(11):1288-93.
2005: Sébastien Pfeffer; Alain Sewer; Mariana Lagos-Quintana; Robert Sheridan; Chris Sander; Friedrich A Grässer; Linda F van Dyk; Kiong Ho; Stewart Shuman; Minchen Chien; James J Russo; Jingyue Ju; Glenn Randall; Brett D Lindenbach; Charles M Rice; Viviana Simon; David D Ho; Mihaela Zavolan; Thomas Tuschl
Identification of microRNAs of the herpesvirus family.
Nature methods 2005;2(4):269-76.
2005: Jin-Biao Ma; Yu-Ren Yuan; Gunter Meister; Yi Pei; Thomas Tuschl; Dinshaw J Patel
Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Nature 2005;434(7033):666-70.
2005: Casper Paludan; Dorothee Schmid; Markus Landthaler; Martina Vockerodt; Martin Hafner; Thomas Tuschl; Christian Münz
Endogenous MHC class II processing of a viral nuclear antigen after autophagy.
Science (New York, N.Y.) 2005;307(5709):593-6.
2005: Alain Sewer; Nicodème Paul; Pablo Landgraf; Alexei A Aravin; Sébastien Pfeffer; Michael J Brownstein; Thomas Tuschl; Erik van Nimwegen; Mihaela Zavolan
Identification of clustered microRNAs using an ab initio prediction method.
BMC bioinformatics 2005;6():267.
2005: Yael Altuvia; Pablo Landgraf; Gila Lithwick; Naama Elefant; Sébastien Pfeffer; Alexei A Aravin; Michael J Brownstein; Thomas Tuschl; Hanah Margalit
Clustering and conservation patterns of human microRNAs.
Nucleic acids research 2005;33(8):2697-706.
2004: Markus Landthaler; Abdullah Yalcin; Thomas Tuschl
The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis.
Current biology : CB 2004;14(23):2162-7.
2004: Matthew N Poy; Lena Eliasson; Jan Krutzfeldt; Satoru Kuwajima; Xiaosong Ma; Patrick E MacDonald; Sébastien Pfeffer; Thomas Tuschl; Nikolaus Rajewsky; Patrik Rorsman; Markus Stoffel
A pancreatic islet-specific microRNA regulates insulin secretion.
Nature 2004;432(7014):226-30.
2004: Bino John; Anton J Enright; Alexei A Aravin; Thomas Tuschl; Chris Sander; Debora S Marks
Human MicroRNA targets.
PLoS biology 2004;2(11):e363.
2004: Gunter Meister; Thomas Tuschl
Mechanisms of gene silencing by double-stranded RNA.
Nature 2004;431(7006):343-9.
2004: Gunter Meister; Markus Landthaler; Agnieszka Patkaniowska; Yair Dorsett; Grace Teng; Thomas Tuschl
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
Molecular cell 2004;15(2):185-97.
2004: Jens Gruber; Guido Boese; Thomas Tuschl; Mary Osborn; Klaus Weber
RNA interference by osmotic lysis of pinosomes: liposome-independent transfection of siRNAs into mammalian cells.
BioTechniques 2004;37(1):96-102.
2004: Bingbing Yuan; Robert Latek; Markus Hossbach; Thomas Tuschl; Fran Lewitter
siRNA Selection Server: an automated siRNA oligonucleotide prediction server.
Nucleic acids research 2004;32(Web Server issue):W130-4.
2004: Cindy L Will; Claudia Schneider; Markus Hossbach; Henning Urlaub; Reinhard Rauhut; Sayda M Elbashir; Thomas Tuschl; Reinhard Lührmann
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.
RNA (New York, N.Y.) 2004;10(6):929-41.
2004: Javier Martinez; Thomas Tuschl
RISC is a 5' phosphomonoester-producing RNA endonuclease.
Genes & development 2004;18(9):975-80.
2004: Sébastien Pfeffer; Mihaela Zavolan; Friedrich A Grässer; Minchen Chien; James J Russo; Jingyue Ju; Bino John; Anton J Enright; Debora Marks; Chris Sander; Thomas Tuschl
Identification of virus-encoded microRNAs.
Science (New York, N.Y.) 2004;304(5671):734-6.
2004: Yair Dorsett; Thomas Tuschl
siRNAs: applications in functional genomics and potential as therapeutics.
Nature reviews. Drug discovery 2004;3(4):318-29.
2004: Gunter Meister; Markus Landthaler; Yair Dorsett; Thomas Tuschl
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing.
RNA (New York, N.Y.) 2004;10(3):544-50.
2003: Alexei A Aravin; Mariana Lagos-Quintana; Abdullah Yalcin; Mihaela Zavolan; Debora Marks; Ben Snyder; Terry Gaasterland; Jutta Meyer; Thomas Tuschl
The small RNA profile during Drosophila melanogaster development.
Developmental cell 2003;5(2):337-50.
2003: Jens Harborth; Sayda M Elbashir; Kim Vandenburgh; Heiko Manninga; Stephen A Scaringe; Klaus Weber; Thomas Tuschl
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.
Antisense & nucleic acid drug development 2003;13(2):83-105.
2003: Victor Ambros; Bonnie Bartel; David P Bartel; Christopher B Burge; James C Carrington; Xuemei Chen; Gideon Dreyfuss; Sean R Eddy; Sam Griffiths-Jones; Mhairi Marshall; Marjori Matzke; Gary Ruvkun; Thomas Tuschl
A uniform system for microRNA annotation.
RNA (New York, N.Y.) 2003;9(3):277-9.
2003: Mariana Lagos-Quintana; Reinhard Rauhut; Jutta Meyer; Arndt Borkhardt; Thomas Tuschl
New microRNAs from mouse and human.
RNA (New York, N.Y.) 2003;9(2):175-9.
2003: Thomas Tuschl
Functional genomics: RNA sets the standard.
Nature 2003;421(6920):220-1.
2003: Anton J Enright; Bino John; Ulrike Gaul; Thomas Tuschl; Chris Sander; Debora S Marks
MicroRNA targets in Drosophila.
Genome biology 2003;5(1):R1.
2003: Javier Martinez; Agnieszka Patkaniowska; Sayda M Elbashir; Jens Harborth; Markus Hossbach; Henning Urlaub; Jutta Meyer; Klaus Weber; Kim Vandenburgh; Heiko Manninga; Stephen A Scaringe; Reinhard Luehrmann; Thomas Tuschl
Analysis of mammalian gene function using small interfering RNAs.
Nucleic acids research. Supplement (2001) 2003;(3):333.
2002: Javier Martinez; Agnieszka Patkaniowska; Henning Urlaub; Reinhard Lührmann; Thomas Tuschl
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.
Cell 2002;110(5):563-74.
2002: Thomas Tuschl; Arndt Borkhardt
Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy.
Molecular interventions 2002;2(3):158-67.
2002: Thomas Tuschl
Expanding small RNA interference.
Nature biotechnology 2002;20(5):446-8.
2002: Mariana Lagos-Quintana; Reinhard Rauhut; Abdullah Yalcin; Jutta Meyer; Winfried Lendeckel; Thomas Tuschl
Identification of tissue-specific microRNAs from mouse.
Current biology : CB 2002;12(9):735-9.
2002: Sayda M Elbashir; Jens Harborth; Klaus Weber; Thomas Tuschl
Analysis of gene function in somatic mammalian cells using small interfering RNAs.
Methods (San Diego, Calif.) 2002;26(2):199-213.
2001: Sayda M Elbashir; Javier Martinez; Agnieszka Patkaniowska; Winfried Lendeckel; Thomas Tuschl
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate.
The EMBO journal 2001;20(23):6877-88.
2001: Jens Harborth; Sayda M Elbashir; K Bechert; Thomas Tuschl; Klaus Weber
Identification of essential genes in cultured mammalian cells using small interfering RNAs.
Journal of cell science 2001;114(Pt 24):4557-65.
2001: Mariana Lagos-Quintana; Reinhard Rauhut; Winfried Lendeckel; Thomas Tuschl
Identification of novel genes coding for small expressed RNAs.
Science (New York, N.Y.) 2001;294(5543):853-8.
2001: György Hutvágner; J McLachlan; Amy E Pasquinelli; E Bálint; Thomas Tuschl; Phillip D Zamore
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA.
Science (New York, N.Y.) 2001;293(5531):834-8.
2001: Sayda M Elbashir; Jens Harborth; Winfried Lendeckel; Abdullah Yalcin; Klaus Weber; Thomas Tuschl
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells.
Nature 2001;411(6836):494-8.
2001: Thomas Tuschl
RNA interference and small interfering RNAs.
Chembiochem : a European journal of chemical biology 2001;2(4):239-45.
2001: Sayda M Elbashir; Winfried Lendeckel; Thomas Tuschl
RNA interference is mediated by 21- and 22-nucleotide RNAs.
Genes & development 2001;15(2):188-200.
2000: Phillip D Zamore; Thomas Tuschl; Phillip A Sharp; David P Bartel
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals.
Cell 2000;101(1):25-33.
1999: Thomas Tuschl; Phillip D Zamore; R Lehmann; David P Bartel; Phillip A Sharp
Targeted mRNA degradation by double-stranded RNA in vitro.
Genes & development 1999;13(24):3191-7.