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Mark Tuszynski
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34
Blesch, Armin
21
Gage, Fred
11
Jones, Leonard
11
Lu, Paul
9
Grill, Ray
9
Conner, James
7
Merrill, David
6
Guest, James
6
Steeves, John
5
Yang, Hong
5
Privat, A
5
Thal, Leon
5
Dobkin, BH
5
Fehlings, MG
5
Blight, Andrew
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All Publications
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2009: Kadoya Ken; Tsukada Shingo; Lu Paul; Coppola Giovanni; Geschwind Dan; Filbin Marie T; Blesch Armin; Tuszynski Mark H
Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury.
Neuron 2009;64(2):165-72.
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2009: Conner James M; Franks Kevin M; Titterness Andrea K; Russell Kyle; Merrill David A; Christie Brian R; Sejnowski Terrence J; Tuszynski Mark H
NGF is essential for hippocampal plasticity and learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(35):10883-9.
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2009: Alto Laura Taylor; Havton Leif A; Conner James M; Hollis Ii Edmund R; Blesch Armin; Tuszynski Mark H
Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury.
Nature neuroscience 2009;12(9):1106-13.
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2009: Blight A; Curt A; Ditunno J F; Dobkin B; Ellaway P; Fawcett J; Fehlings M; Grossman R G; Lammertse D P; Privat A; Steeves J; Tuszynski M; Kalichman M; Guest J D
Position statement on the sale of unproven cellular therapies for spinal cord injury: the international campaign for cures of spinal cord injury paralysis.
Spinal cord : the official journal of the International Medical Society of Paraplegia 2009;47(9):713-4.
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2009: Alfa Ronald W; Tuszynski Mark H; Blesch Armin
A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth.
Journal of neuroscience research 2009;87(12):2624-31.
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2009: Ramanathan Dhakshin; Tuszynski Mark H; Conner James M
The basal forebrain cholinergic system is required specifically for behaviorally mediated cortical map plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(18):5992-6000.
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2009: Hollis Edmund R; Jamshidi Pouya; Löw Karin; Blesch Armin; Tuszynski Mark H
Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(17):7215-20.
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2009: Nagahara Alan H; Merrill David A; Coppola Giovanni; Tsukada Shingo; Schroeder Brock E; Shaked Gideon M; Wang Ling; Blesch Armin; Kim Albert; Conner James M; Rockenstein Edward; Chao Moses V; Koo Edward H; Geschwind Daniel; Masliah Eliezer; Chiba Andrea A; Tuszynski Mark H
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease.
Nature medicine 2009;15(3):331-7.
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2009: Rosenzweig Ephron S; Brock John H; Culbertson Maya D; Lu Paul; Moseanko Rod; Edgerton V Reggie; Havton Leif A; Tuszynski Mark H
Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys.
The Journal of comparative neurology 2009;513(2):151-63.
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2009: Nagahara Alan H; Bernot Tim; Moseanko Rod; Brignolo Laurie; Blesch Armin; Conner James M; Ramirez Anthony; Gasmi Mehdi; Tuszynski Mark H
Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery.
Experimental neurology 2009;215(1):153-9.
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2009: Blesch Armin; Tuszynski Mark H
Spinal cord injury: plasticity, regeneration and the challenge of translational drug development.
Trends in neurosciences 2009;32(1):41-7.
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2009: Hollis Edmund R; Lu Paul; Blesch Armin; Tuszynski Mark H
IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury.
Experimental neurology 2009;215(1):53-9.
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2008: Herzog Christopher D; Dass Biplob; Gasmi Mehdi; Bakay Roy; Stansell James E; Tuszynski Mark; Bankiewicz Krystof; Chen Er-Yun; Chu Yaping; Bishop Kathie; Kordower Jeffrey H; Bartus Raymond T
Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(10):1737-44.
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2008: Bishop Kathie M; Hofer Eva K; Mehta Arpesh; Ramirez Anthony; Sun Liangwu; Tuszynski Mark; Bartus Raymond T
Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons.
Experimental neurology 2008;211(2):574-84.
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2008: Khachaturian Zaven S; Petersen Ronald C; Gauthier Serge; Buckholtz Neil; Corey-Bloom Jodey P; Evans Bill; Fillit Howard; Foster Norman; Greenberg Barry; Grundman Michael; Sano Mary; Simpkins James; Schneider Lon S; Weiner Michael W; Galasko Doug; Hyman Bradley; Kuller Lew; Schenk Dale; Snyder Stephen; Thomas Ronald G; Tuszynski Mark H; Vellas Bruno; Wurtman Richard J; Snyder Peter J; Frank Richard A; Albert Marilyn; Doody Rachelle; Ferris Steven; Kaye Jeffrey; Koo Edward; Morrison-Bogorad Marcelle; Reisberg Barry; Salmon David P; Gilman Sid; Mohs Richard; Aisen Paul S; Breitner John C S; Cummings Jeffrey L; Kawas Claudia; Phelps Creighton; Poirier Judes; Sabbagh Marwan; Touchon Jacques; Khachaturian Ara S; Bain Lisa J
A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(3):156-63.
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2008: Hollis Edmund R; Kadoya Ken; Hirsch Matthew; Samulski Richard J; Tuszynski Mark H
Efficient retrograde neuronal transduction utilizing self-complementary AAV1.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(2):296-301.
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2008: Lu Paul; Tuszynski Mark H
Growth factors and combinatorial therapies for CNS regeneration.
Experimental neurology 2008;209(2):313-20.
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2008: Löw Karin; Culbertson Maya; Bradke Frank; Tessier-Lavigne Marc; Tuszynski Mark H
Netrin-1 is a novel myelin-associated inhibitor to axon growth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(5):1099-108.
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2007: Aiuti A; Bachoud-Lévi A C; Blesch A; Brenner M K; Cattaneo F; Chiocca E A; Gao G; High K A; Leen A M; Lemoine N R; McNeish I A; Meneguzzi G; Peschanski M; Roncarolo M G; Strayer D S; Tuszynski M H; Waxman D J; Wilson J M
Progress and prospects: gene therapy clinical trials (part 2).
Gene therapy 2007;14(22):1555-63.
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2007: Tuszynski Mark H
Rebuilding the brain: resurgence of fetal grafting.
Nature neuroscience 2007;10(10):1229-30.
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2007: Blesch Armin; Tuszynski Mark H
Transient growth factor delivery sustains regenerated axons after spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(39):10535-45.
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2007: Tuszynski Mark H
Nerve growth factor gene delivery: animal models to clinical trials.
Developmental neurobiology 2007;67(9):1204-15.
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2007: Herzog Christopher D; Dass Biplob; Holden James E; Stansell James; Gasmi Mehdi; Tuszynski Mark H; Bartus Raymond T; Kordower Jeffrey H
Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys.
Movement disorders : official journal of the Movement Disorder Society 2007;22(8):1124-32.
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2007: Tuszynski Mark H
Nerve growth factor gene therapy in Alzheimer disease.
Alzheimer disease and associated disorders 2007;21(2):179-89.
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2007: Fawcett J W; Curt A; Steeves J D; Coleman W P; Tuszynski M H; Lammertse D; Bartlett P F; Blight A R; Dietz V; Ditunno J; Dobkin B H; Havton L A; Ellaway P H; Fehlings M G; Privat A; Grossman R; Guest J D; Kleitman N; Nakamura M; Gaviria M; Short D
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials.
Spinal cord : the official journal of the International Medical Society of Paraplegia 2007;45(3):190-205.
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2007: Steeves J D; Lammertse D; Curt A; Fawcett J W; Tuszynski M H; Ditunno J F; Ellaway P H; Fehlings M G; Guest J D; Kleitman N; Bartlett P F; Blight A R; Dietz V; Dobkin B H; Grossman R; Short D; Nakamura M; Coleman W P; Gaviria M; Privat A;
Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures.
Spinal cord : the official journal of the International Medical Society of Paraplegia 2007;45(3):206-21.
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2007: Tuszynski M H; Steeves J D; Fawcett J W; Lammertse D; Kalichman M; Rask C; Curt A; Ditunno J F; Fehlings M G; Guest J D; Ellaway P H; Kleitman N; Bartlett P F; Blight A R; Dietz V; Dobkin B H; Grossman R; Privat A;
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics.
Spinal cord : the official journal of the International Medical Society of Paraplegia 2007;45(3):222-31.
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2007: Lammertse D; Tuszynski M H; Steeves J D; Curt A; Fawcett J W; Rask C; Ditunno J F; Fehlings M G; Guest J D; Ellaway P H; Kleitman N; Blight A R; Dobkin B H; Grossman R; Katoh H; Privat A; Kalichman M;
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design.
Spinal cord : the official journal of the International Medical Society of Paraplegia 2007;45(3):232-42.
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2007: Lu Paul; Jones Leonard L; Tuszynski Mark H
Axon regeneration through scars and into sites of chronic spinal cord injury.
Experimental neurology 2007;203(1):8-21.
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2007: Bartus Raymond T; Herzog Christopher D; Bishop Kathie; Ostrove Jeffrey M; Tuszynski Mark; Kordower Jeffrey H; Gasmi Mehdi
Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point.
Parkinsonism & related disorders 2007;13 Suppl 3():S469-77.
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2006: Blurton-Jones Mathew; Tuszynski Mark H
Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF.
The Journal of comparative neurology 2006;499(4):603-12.
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2006: Tuszynski Mark
Challenges to the report of Nogo antibody effects in primates.
Nature medicine 2006;12(11):1231-2; author reply 1232-3.
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2006: Stokols Shula; Sakamoto Jeff; Breckon Chris; Holt Todd; Weiss James; Tuszynski Mark H
Templated agarose scaffolds support linear axonal regeneration.
Tissue engineering 2006;12(10):2777-87.
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2006: Lu Paul; Yang Hong; Culbertson Maya; Graham Lori; Roskams A Jane; Tuszynski Mark H
Olfactory ensheathing cells do not exhibit unique migratory or axonal growth-promoting properties after spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(43):11120-30.
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2006: Taylor Laura; Jones Leonard; Tuszynski Mark H; Blesch Armin
Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(38):9713-21.
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2006: Ramanathan Dhakshin; Conner James M; Tuszynski Mark H
A form of motor cortical plasticity that correlates with recovery of function after brain injury.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(30):11370-5.
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2006: Blight Andrew R; Tuszynski Mark H
Clinical trials in spinal cord injury.
Journal of neurotrauma 2006;23(3-4):586-93.
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2006: Yang Hong; Lu Paul; McKay Heather M; Bernot Tim; Keirstead Hans; Steward Oswald; Gage Fred H; Edgerton V Reggie; Tuszynski Mark H
Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(8):2157-66.
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2006: Stokols Shula; Tuszynski Mark H
Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury.
Biomaterials 2006;27(3):443-51.
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2005: Courtine Grégoire; Roy Roland R; Raven Joseph; Hodgson John; McKay Heather; Yang Hong; Zhong Hui; Tuszynski Mark H; Edgerton V Reggie
Performance of locomotion and foot grasping following a unilateral thoracic corticospinal tract lesion in monkeys (Macaca mulatta).
Brain : a journal of neurology 2005;128(Pt 10):2338-58.
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2005: Anderson D K; Beattie M; Blesch A; Bresnahan J; Bunge M; Dietrich D; Dietz V; Dobkin B; Fawcett J; Fehlings M; Fischer I; Grossman R; Guest J; Hagg T; Hall E D; Houle J; Kleitman N; McDonald J; Murray M; Privat A; Reier P; Steeves J; Steward O; Tetzlaff W; Tuszynski M H; Waxman S G; Whittemore S; Wolpaw J; Young W; Zheng B
Recommended guidelines for studies of human subjects with spinal cord injury.
Spinal cord : the official journal of the International Medical Society of Paraplegia 2005;43(8):453-8.
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2005: Blesch Armin; Conner James; Pfeifer Alexander; Gasmi Mehdi; Ramirez Anthony; Britton William; Alfa Ron; Verma Inder; Tuszynski Mark H
Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(6):916-25.
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2005: Lu P; Tuszynski M H
Can bone marrow-derived stem cells differentiate into functional neurons?
Experimental neurology 2005;193(2):273-8.
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2005: Courtine Grégoire; Roy Roland R; Hodgson John; McKay Heather; Raven Joseph; Zhong Hui; Yang Hong; Tuszynski Mark H; Edgerton V Reggie
Kinematic and EMG determinants in quadrupedal locomotion of a non-human primate (Rhesus).
Journal of neurophysiology 2005;93(6):3127-45.
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2005: Tuszynski Mark H; Thal Leon; Pay Mary; Salmon David P; U Hoi Sang; Bakay Roy; Patel Piyush; Blesch Armin; Vahlsing H Lee; Ho Gilbert; Tong Gang; Potkin Steven G; Fallon James; Hansen Lawrence; Mufson Elliott J; Kordower Jeffrey H; Gall Christine; Conner James
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease.
Nature medicine 2005;11(5):551-5.
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2005: Conner James M; Chiba Andrea A; Tuszynski Mark H
The basal forebrain cholinergic system is essential for cortical plasticity and functional recovery following brain injury.
Neuron 2005;46(2):173-9.
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2005: Lu P; Jones L L; Tuszynski M H
BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury.
Experimental neurology 2005;191(2):344-60.
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2005: Tuszynski M H
New strategies for CNS repair.
Ernst Schering Research Foundation workshop 2005;(53):1-10.
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2004: Stokols Shula; Tuszynski Mark H
The fabrication and characterization of linearly oriented nerve guidance scaffolds for spinal cord injury.
Biomaterials 2004;25(27):5839-46.
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2004: Steeves J; Fawcett J; Tuszynski M
Report of international clinical trials workshop on spinal cord injury February 20-21, 2004, Vancouver, Canada.
Spinal cord : the official journal of the International Medical Society of Paraplegia 2004;42(10):591-7.
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2004: Lu Paul; Yang Hong; Jones Leonard L; Filbin Marie T; Tuszynski Mark H
Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(28):6402-9.
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2004: Lu Paul; Blesch Armin; Tuszynski Mark H
Induction of bone marrow stromal cells to neurons: differentiation, transdifferentiation, or artifact?
Journal of neuroscience research 2004;77(2):174-91.
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2004: Blesch Armin; Tuszynski Mark H
Gene therapy and cell transplantation for Alzheimer's disease and spinal cord injury.
Yonsei medical journal 2004;45 Suppl():28-31.
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2004: Imitola Jaime; Park Kook In; Teng Yang D; Nisim Sahar; Lachyankar Mahesh; Ourednik Jitka; Mueller Franz-Josef; Yiou Rene; Atala Anthony; Sidman Richard L; Tuszynski Mark; Khoury Samia J; Snyder Evan Y
Stem cells: cross-talk and developmental programs.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1445):823-37.
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2004: Nagahara Alan; Tuszynski Mark H
The ageless question--what accounts for age-related cognitive decline?
Science of aging knowledge environment : SAGE KE 2004;2004(19):pe20.
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2004: Smith David E; Rapp Peter R; McKay Heather M; Roberts Jeffrey A; Tuszynski Mark H
Memory impairment in aged primates is associated with focal death of cortical neurons and atrophy of subcortical neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(18):4373-81.
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2004: Lacroix Steve; Havton Leif A; McKay Heather; Yang Hong; Brant Adam; Roberts Jeffrey; Tuszynski Mark H
Bilateral corticospinal projections arise from each motor cortex in the macaque monkey: a quantitative study.
The Journal of comparative neurology 2004;473(2):147-61.
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2004: Blesch Armin; Tuszynski Mark H
Nucleus hears axon's pain.
Nature medicine 2004;10(3):236-7.
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2004: Blurton-Jones M; Kuan P N; Tuszynski M H
Anatomical evidence for transsynaptic influences of estrogen on brain-derived neurotrophic factor expression.
The Journal of comparative neurology 2004;468(3):347-60.
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2004: Tuszynski Mark H; Blesch Armin
Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease.
Progress in brain research 2004;146():441-9.
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2003: Blesch Armin; Tuszynski Mark H
Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and induces remyelination.
The Journal of comparative neurology 2003;467(3):403-17.
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2003: Tobias C A; Shumsky J S; Shibata M; Tuszynski M H; Fischer I; Tessler A; Murray M
Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration.
Experimental neurology 2003;184(1):97-113.
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2003: Jones Leonard L; Sajed Dana; Tuszynski Mark H
Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: a balance of permissiveness and inhibition.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(28):9276-88.
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2003: Jones Leonard L; Margolis Richard U; Tuszynski Mark H
The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury.
Experimental neurology 2003;182(2):399-411.
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2003: Tuszynski Mark H
Gene therapy for neurological disease.
Expert opinion on biological therapy 2003;3(5):815-28.
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2003: Conner James M; Culberson Andrew; Packowski Christine; Chiba Andrea A; Tuszynski Mark H
Lesions of the Basal forebrain cholinergic system impair task acquisition and abolish cortical plasticity associated with motor skill learning.
Neuron 2003;38(5):819-29.
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2003: Lu P; Jones L L; Snyder E Y; Tuszynski M H
Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury.
Experimental neurology 2003;181(2):115-29.
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2003: Tuszynski Mark H; Grill Ray; Jones Leonard L; Brant Adam; Blesch Armin; Löw Karin; Lacroix Steve; Lu Paul
NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection.
Experimental neurology 2003;181(1):47-56.
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2003: Merrill David A; Karim Rajiv; Darraq Michael; Chiba Andrea A; Tuszynski Mark H
Hippocampal cell genesis does not correlate with spatial learning ability in aged rats.
The Journal of comparative neurology 2003;459(2):201-7.
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2002: Lacroix Steve; Chang Leon; Rose-John Stefan; Tuszynski Mark H
Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth.
The Journal of comparative neurology 2002;454(3):213-28.
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2002: Tuszynski Mark H; U Hoi Sang; Alksne John; Bakay Roy A; Pay Mary Margaret; Merrill David; Thal Leon J
Growth factor gene therapy for Alzheimer disease.
Neurosurgical focus 2002;13(5):e5.
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2002: Blurton-Jones Mathew; Tuszynski Mark H
Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats.
The Journal of comparative neurology 2002;452(3):276-87.
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2002: Tuszynski Mark H; Thal Leon; U Hoi-Sang; Pay Mary Margaret; Blesch Armin; Conner James; Vahlsing H Lee
Nerve growth factor gene therapy for Alzheimer's disease.
Journal of molecular neuroscience : MN 2002;19(1-2):207.
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2002: Tuszynski Mark H; Grill Ray; Jones Leonard L; McKay Heather M; Blesch Armin
Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts.
The Journal of comparative neurology 2002;449(1):88-101.
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2002: Jones Leonard L; Tuszynski Mark H
Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(11):4611-24.
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2002: Tuszynski Mark H
Growth-factor gene therapy for neurodegenerative disorders.
Lancet neurology 2002;1(1):51-7.
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2002: Blesch Armin; Lu Paul; Tuszynski Mark H
Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair.
Brain research bulletin 2002;57(6):833-8.
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2002: Jones Leonard L; Yamaguchi Yu; Stallcup William B; Tuszynski Mark H
NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2792-803.
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2002: Merrill David A; Blesch Armin; Tuszynski Mark H
Therapeutic potential of nervous system growth factors for neurodegenerative disease.
Expert review of neurotherapeutics 2002;2(1):89-96.
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2002: Blesch Armin; Tuszynski Mark H
Spontaneous and neurotrophin-induced axonal plasticity after spinal cord injury.
Progress in brain research 2002;137():415-23.
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2002: Tuszynski Mark H; Conner James; Blesch Armin; Smith David; Merrill David A; Vahlsing H Lee
New strategies in neural repair.
Progress in brain research 2002;138():401-9.
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2002: Weidner N; Tuszynski M H
Spontaneous plasticity in the injured spinal cord-implications for repair strategies.
Molecular psychiatry 2002;7(1):9-11.
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2001: Merrill D A; Chiba A A; Tuszynski M H
Conservation of neuronal number and size in the entorhinal cortex of behaviorally characterized aged rats.
The Journal of comparative neurology 2001;438(4):445-56.
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2001: Jones L L; Tuszynski M H
Chronic intrathecal infusions after spinal cord injury cause scarring and compression.
Microscopy research and technique 2001;54(5):317-24.
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2001: Lu P; Blesch A; Tuszynski M H
Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons.
The Journal of comparative neurology 2001;436(4):456-70.
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2001: Blesch A; Tuszynski M H
GDNF gene delivery to injured adult CNS motor neurons promotes axonal growth, expression of the trophic neuropeptide CGRP, and cellular protection.
The Journal of comparative neurology 2001;436(4):399-410.
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2001: Blesch A; Conner J M; Tuszynski M H
Modulation of neuronal survival and axonal growth in vivo by tetracycline-regulated neurotrophin expression.
Gene therapy 2001;8(12):954-60.
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2001: Jones L L; Oudega M; Bunge M B; Tuszynski M H
Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury.
The Journal of physiology 2001;533(Pt 1):83-9.
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2001: Blurton-Jones M; Tuszynski M H
Reactive astrocytes express estrogen receptors in the injured primate brain.
The Journal of comparative neurology 2001;433(1):115-23.
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2001: Weidner N; Ner A; Salimi N; Tuszynski M H
Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3513-8.
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2001: Conner J M; Darracq M A; Roberts J; Tuszynski M H
Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1941-6.
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2000: Bowes M; Tuszynski M H; Conner J; Zivin J A
Continuous intrathecal fluid infusions elevate nerve growth factor levels and prevent functional deficits after spinal cord ischemia.
Brain research 2000;883(2):178-83.
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2000: Tuszynski M H
Intraparenchymal NGF infusions rescue degenerating cholinergic neurons.
Cell transplantation 2000;9(5):629-36.
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2000: Merrill D A; Roberts J A; Tuszynski M H
Conservation of neuron number and size in entorhinal cortex layers II, III, and V/VI of aged primates.
The Journal of comparative neurology 2000;422(3):396-401.
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2000: Blesch A; Uy H S; Diergardt N; Tuszynski M H
Neurite outgrowth can be modulated in vitro using a tetracycline-repressible gene therapy vector expressing human nerve growth factor.
Journal of neuroscience research 2000;59(3):402-9.
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2000: Lacroix S; Tuszynski M H
Neurotrophic factors and gene therapy in spinal cord injury.
Neurorehabilitation and neural repair 2000;14(4):265-75.
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1999: Weidner N; Grill R J; Tuszynski M H
Elimination of basal lamina and the collagen "scar" after spinal cord injury fails to augment corticospinal tract regeneration.
Experimental neurology 1999;160(1):40-50.
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1999: Weidner N; Blesch A; Grill R J; Tuszynski M H
Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1.
The Journal of comparative neurology 1999;413(4):495-506.
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1999: Smith D E; Roberts J; Gage F H; Tuszynski M H
Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10893-8.
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1999: Tuszynski M H; Gabriel K; Gerhardt K; Szollar S
Human spinal cord retains substantial structural mass in chronic stages after injury.
Journal of neurotrauma 1999;16(6):523-31.
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1999: Blesch A; Uy H S; Grill R J; Cheng J G; Patterson P H; Tuszynski M H
Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(9):3556-66.
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1999: Blurton-Jones M M; Roberts J A; Tuszynski M H
Estrogen receptor immunoreactivity in the adult primate brain: neuronal distribution and association with p75, trkA, and choline acetyltransferase.
The Journal of comparative neurology 1999;405(4):529-42.
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1999: Tuszynski M; Edgerton R; Dobkin B
Recovery of locomotion after experimental spinal cord injury: axonal regeneration or modulation of intrinsic spinal cord walking circuitry?
The journal of spinal cord medicine 1999;22(2):143.
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1998: Tuszynski M H; Smith D E; Roberts J; McKay H; Mufson E
Targeted intraparenchymal delivery of human NGF by gene transfer to the primate basal forebrain for 3 months does not accelerate beta-amyloid plaque deposition.
Experimental neurology 1998;154(2):573-82.
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1998: Tuszynski M H; Weidner N; McCormack M; Miller I; Powell H; Conner J
Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth, and myelination.
Cell transplantation 1998;7(2):187-96.
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1998: Blesch A; Grill R J; Tuszynski M H
Neurotrophin gene therapy in CNS models of trauma and degeneration.
Progress in brain research 1998;117():473-84.
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1997: Tuszynski M H
Gene therapy for nervous system disease.
Annals of the New York Academy of Sciences 1997;835():1-11.
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1997: Grill R J; Blesch A; Tuszynski M H
Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells.
Experimental neurology 1997;148(2):444-52.
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1997: Eberling J L; Roberts J A; Rapp P R; Tuszynski M H; Jagust W J
Cerebral glucose metabolism and memory in aged rhesus macaques.
Neurobiology of aging 1997;18(4):437-43.
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1997: Grill R; Murai K; Blesch A; Gage F H; Tuszynski M H
Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5560-72.
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1997: Tuszynski M H; Murai K; Blesch A; Grill R; Miller I
Functional characterization of NGF-secreting cell grafts to the acutely injured spinal cord.
Cell transplantation 1997;6(3):361-8.
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1997: Winkler J; Ramirez G A; Kuhn H G; Peterson D A; Day-Lollini P A; Stewart G R; Tuszynski M H; Gage F H; Thal L J
Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor.
Annals of neurology 1997;41(1):82-93.
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1996: Thal L J; Carta A; Clarke W R; Ferris S H; Friedland R P; Petersen R C; Pettegrew J W; Pfeiffer E; Raskind M A; Sano M; Tuszynski M H; Woolson R F
A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease.
Neurology 1996;47(3):705-11.
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1996: Tuszynski M H; Mafong E; Meyer S
Central infusions of brain-derived neurotrophic factor and neurotrophin-4/5, but not nerve growth factor and neurotrophin-3, prevent loss of the cholinergic phenotype in injured adult motor neurons.
Neuroscience 1996;71(3):761-71.
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1996: Tuszynski M H; Roberts J; Senut M C; U H S; Gage F H
Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration.
Gene therapy 1996;3(4):305-14.
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1996: Nakahara Y; Gage F H; Tuszynski M H
Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord.
Cell transplantation 1996;5(2):191-204.
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1996: Tuszynski M H; Gabriel K; Gage F H; Suhr S; Meyer S; Rosetti A
Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury.
Experimental neurology 1996;137(1):157-73.
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1996: Tuszynski M H; Gage F H
Somatic gene therapy for nervous system disease.
Ciba Foundation symposium 1996;196():85-94; discussion 94-7.
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1995: Senut M C; Tuszynski M H; Raymon H K; Suhr S T; Liou N H; Jones K R; Reichardt L F; Gage F H
Regional differences in responsiveness of adult CNS axons to grafts of cells expressing human neurotrophin 3.
Experimental neurology 1995;135(1):36-55.
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1995: Tuszynski M H; Gage F H
Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4621-5.
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1995: Tuszynski M H; Gage F H
Maintaining the neuronal phenotype after injury in the adult CNS. Neurotrophic factors, axonal growth substrates, and gene therapy.
Molecular neurobiology 1995;10(2-3):151-67.
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1995: Blesch A; Tuszynski M
Ex vivo gene therapy for Alzheimer's disease and spinal cord injury.
Clinical neuroscience (New York, N.Y.) 1995;3(5):268-74.
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1994: Tuszynski M H; Senut M C; Ray J; Roberts J
Somatic gene transfer to the adult primate central nervous system: in vitro and in vivo characterization of cells genetically modified to secrete nerve growth factor.
Neurobiology of disease 1994;1(1-2):67-78.
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1994: Tuszynski M H; Peterson D A; Ray J; Baird A; Nakahara Y; Gage F H
Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord.
Experimental neurology 1994;126(1):1-14.
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1994: Tuszynski M H; Gage F H
Neurotrophic factors and diseases of the nervous system.
Annals of neurology 1994;35 Suppl():S9-12.
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1992: Hainline B; Tuszynski M H; Posner J B
Ataxia in epidural spinal cord compression.
Neurology 1992;42(11):2193-5.
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1991: Tuszynski M H; Sang H; Yoshida K; Gage F H
Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain.
Annals of neurology 1991;30(5):625-36.
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1991: Gage F H; Tuszynski M H; Chen K S; Fagan A M; Higgins G A
Nerve growth factor function in the central nervous system.
Current topics in microbiology and immunology 1991;165():71-93.
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1991: Tuszynski M H; Gage F H
In vivo assay of neuron-specific effects of nerve growth factor.
Methods in enzymology 1991;198():35-48.
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1990: Tuszynski M H; U H S; Amaral D G; Gage F H
Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(11):3604-14.
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1990: Barnett J; Baecker P; Routledge-Ward C; Bursztyn-Pettegrew H; Chow J; Nguyen B; Bach C; Chan H; Tuszynski M H; Yoshida K
Human beta nerve growth factor obtained from a baculovirus expression system has potent in vitro and in vivo neurotrophic activity.
Experimental neurology 1990;110(1):11-24.
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1990: Tuszynski M H; Armstrong D M; Gage F H
Basal forebrain cell loss following fimbria/fornix transection.
Brain research 1990;508(2):241-8.
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1990: Tuszynski M H; Gage F H
Potential use of neurotrophic agents in the treatment of neurodegenerative disorders.
Acta neurobiologiae experimentalis 1990;50(4-5):311-22.
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1990: Gage F H; Rosenberg M B; Tuszynski M H; Yoshida K; Armstrong D M; Hayes R C; Friedmann T
Gene therapy in the CNS: intracerebral grafting of genetically modified cells.
Progress in brain research 1990;86():205-17.
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1990: Gage F H; Fisher L J; Jinnah H A; Rosenberg M B; Tuszynski M H; Friedmann T
Grafting genetically modified cells to the brain: conceptual and technical issues.
Progress in brain research 1990;82():1-10.
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1990: Tuszynski M H; Buzsaki G; Gage F H
Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection.
Neuroscience 1990;36(1):33-44.
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1989: Tuszynski M H; Jinnah H A; Gage F H
Delivery of neuroactive compounds to the brain: potential utility of genetically modified cells.
Neurobiology of aging 1989;10(5):644-5; discussion 648-50.
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1989: Chen K S; Tuszynski M H; Gage F H
Role of neurotrophic factors in Alzheimer's disease.
Neurobiology of aging 1989;10(5):545-6; discussion 552-3.
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1989: Tuszynski M H; Petito C K; Levy D E
Risk factors and clinical manifestations of pathologically verified lacunar infarctions.
Stroke; a journal of cerebral circulation 1989;20(8):990-9.
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1989: Gage F H; Tuszynski M H; Chen K S; Armstrong D; Buzsáki G
Survival, growth and function of damaged cholinergic neurons.
EXS 1989;57():259-74.
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1988: Rosenberg M B; Friedmann T; Robertson R C; Tuszynski M; Wolff J A; Breakefield X O; Gage F H
Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression.
Science (New York, N.Y.) 1988;242(4885):1575-8.
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1988: Tuszynski M H; Petito C K
Ischemic thalamic aphasia with pathologic confirmation.
Neurology 1988;38(5):800-2.
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