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Yogesh Tyagi

Research Profile

Chemicals & Drugs

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Acetylation

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Micronucleus Tests

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Ranju Kumari; Seema Bansal; Garima Gupta; Shvetambri Arora; Ajit Kumar; Sanjay Goel; Prabhjot Singh; Prija Ponnan; Nivedita Priya; Tapesh K Tyagi; Anil S Baghel; Sushma Manral; Rashmi Tandon; Rini Joshi; Vishwajeet Rohil; Marco Gaspari; Ekta Kohli; Yogesh K Tyagi; Bilikere S Dwarakanath; Daman Saluja; Suvro Chatterji; Sunil K Sharma; Ashok K Prasad; Ramesh C Rastogi; Hanumantharao G Raj; Virinder S Parmar
Calreticulin transacylase: genesis, mechanism of action and biological applications.
Shvetambri Arora; Yogesh K Tyagi; Ajit Kumar; Syamantak Majumder; Daman Saluja; Hanumantharao G Raj; Suvro Chatterjee; Luciano Saso; Ashok K Prasad; Virinder S Parmar
The role of calreticulin transacetylase in the activation of human platelet nitrite reductase by polyphenolic acetates.
Shvetambri Arora; Parag Vohra; Ajit Kumar; Yogesh K Tyagi; Hanumantharao G Raj; Bilekere Srinivasarao Dawarkanath; Daman Saluja; Luciano Saso; Virinder S Parmar
Calreticulin transacetylase catalyzed activation of rat tracheal smooth muscle cell nitric oxide synthase by acetoxycoumarins.

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All Publications

2010: Ranju Kumari; Seema Bansal; Garima Gupta; Shvetambri Arora; Ajit Kumar; Sanjay Goel; Prabhjot Singh; Prija Ponnan; Nivedita Priya; Tapesh K Tyagi; Anil S Baghel; Sushma Manral; Rashmi Tandon; Rini Joshi; Vishwajeet Rohil; Marco Gaspari; Ekta Kohli; Yogesh K Tyagi; Bilikere S Dwarakanath; Daman Saluja; Suvro Chatterji; Sunil K Sharma; Ashok K Prasad; Ramesh C Rastogi; Hanumantharao G Raj; Virinder S Parmar
Calreticulin transacylase: genesis, mechanism of action and biological applications.
Biochimie 2010;92(9):1173-9.
2009: Shvetambri Arora; Yogesh K Tyagi; Ajit Kumar; Syamantak Majumder; Daman Saluja; Hanumantharao G Raj; Suvro Chatterjee; Luciano Saso; Ashok K Prasad; Virinder S Parmar
The role of calreticulin transacetylase in the activation of human platelet nitrite reductase by polyphenolic acetates.
Biological & pharmaceutical bulletin 2009;32(2):161-5.
2008: Shvetambri Arora; Parag Vohra; Ajit Kumar; Yogesh K Tyagi; Hanumantharao G Raj; Bilekere Srinivasarao Dawarkanath; Daman Saluja; Luciano Saso; Virinder S Parmar
Calreticulin transacetylase catalyzed activation of rat tracheal smooth muscle cell nitric oxide synthase by acetoxycoumarins.
Biological & pharmaceutical bulletin 2008;31(4):709-13.
2008: Seema Bansal; Marco Gaspari; Hanumantharao G Raj; Ajit Kumar; Giovanni Cuda; Elwin Verheij; Yogesh K Tyagi; Prija Ponnan; Ramesh C Rastogi; Virinder S Parmar
Calreticulin transacetylase mediates the acetylation of nitric oxide synthase by polyphenolic acetate.
Applied biochemistry and biotechnology 2008;144(1):37-45.
2007: Ajit Kumar; Brajendra K Singh; Nawal K Sharma; Kapil Gyanda; Sapan K Jain; Yogesh K Tyagi; Anil S Baghel; Mukesh Pandey; Sunil K Sharma; Ashok K Prasad; Subhash C Jain; Ramesh C Rastogi; Hanumantharao G Raj; Arthur C Watterson; Erik Van Der Eycken; Virinder S Parmar
Specificities of acetoxy derivatives of coumarins, biscoumarins, chromones, flavones, isoflavones and xanthones for acetoxy drug: protein transacetylase.
European journal of medicinal chemistry 2007;42(4):447-55.
2007: Ranju Kumari; Garima Gupta; Daman Saluja; Ajit Kumar; Sanjay Goel; Yogesh K Tyagi; Ruchika Gulati; Anjali Vinocha; Kambadoor Muralidhar; Bilikere S Dwarakanth; Ramesh C Rastogi; Virinder S Parmar; Shamkant A Patkar; Hanumantharao G Raj
Characterization of protein transacetylase from human placenta as a signaling molecule calreticulin using polyphenolic peracetates as the acetyl group donors.
Cell biochemistry and biophysics 2007;47(1):53-64.
2007: Ajit Kumar; Yogesh K Tyagi; Prija Ponnan; Vishwajeet Rohil; Ashok K Prasad; Bilekere S Dwarkanath; Virinder S Parmar; Hanumantharao G Raj
Ellagic acid peracetate is superior to ellagic acid in the prevention of genotoxicity due to aflatoxin B1 in bone marrow and lung cells.
The Journal of pharmacy and pharmacology 2007;59(1):81-6.
2006: Pulkit Khurana; Ranju Kumari; Parag Vohra; Ajit Kumar; Garima Gupta; Hanumantharao G Raj; Bilikere S Dwarakanath; Virinder S Parmar; Daman Saluja; Mridula Bose; Anjana Vij; Nabo K Chaudhary; Jawahar S Adhikari; Yogesh K Tyagi; Ekta Kohli
Acetoxy drug: protein transacetylase catalyzed activation of human platelet nitric oxide synthase by polyphenolic peracetates.
Bioorganic & medicinal chemistry 2006;14(2):575-83.
2005: Pankaj Kumar; Madhu Khanna; Vikram Srivastava; Yogesh K Tyagi; Hanumantharao G Raj; K Ravi
Effect of quercetin supplementation on lung antioxidants after experimental influenza virus infection.
Experimental lung research 2005;31(5):449-59.
2005: Yogesh K Tyagi; Ajit Kumar; Hanumantharao G Raj; Parag Vohra; Garima Gupta; Ranju Kumari; Pankaj Kumar; Rajinder K Gupta
Synthesis of novel amino and acetyl amino-4-methylcoumarins and evaluation of their antioxidant activity.
European journal of medicinal chemistry 2005;40(4):413-20.
2004: Ekta Kohli; Marco Gaspari; Hanumantharao G Raj; Virinder S Parmar; Sunil K Sharma; Jan van der Greef; Ranju Kumari; Garima Gupta; Pulkit Khurana; Yogesh K Tyagi; Arthur C Watterson; Carl E Olsen
Acetoxy drug: protein transacetylase of buffalo liver-characterization and mass spectrometry of the acetylated protein product.
Biochimica et biophysica acta 2004;1698(1):55-66.
2003: Hanumantharao G Raj; Ishwar Singh; Ekta Kohli; Ranju Kumari; Garima Gupta; Yogesh K Tyagi; Ajit Kumar; Ashok K Prasad; Narendra K Kaushik; Carl E Olsen; Arthur C Watterson; Virinder S Parmar
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 10: identification of inhibitors for the liver microsomal acetoxycoumarin: protein transacetylase.
Bioorganic & medicinal chemistry 2003;11(6):1015-9.
2002: Ishwar Singh; Ekta Kohli; Hanumantharao G Raj; Kapil Gyanda; Sapan K Jain; Yogesh K Tyagi; Garima Gupta; Ranju Kumari; Ajit Kumar; Giridhari Pal; Ashok K Prasad; Ramesh C Rastogi; Carl E Olsen; Subhash C Jain; Virinder S Parmar
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 9: comparison of acetoxy 4-methylcoumarins and other polyphenolic acetates reveal the specificity to acetoxy drug: protein transacetylase for pyran carbonyl group in proximity to the oxygen heteroatom.
Bioorganic & medicinal chemistry 2002;10(12):4103-11.
2002: Ekta Kohli; Marco Gaspari; Hanumantharao G Raj; Virinder S Parmar; Jan van der Greef; Garima Gupta; Ranju Kumari; Ashok K Prasad; Sanjay Goel; Giridhari Pal; Yogesh K Tyagi; Subhash C Jain; Nizamuddin Ahmad; Arthur C Watterson; Carl E Olsen
Establishment of the enzymatic protein acetylation independent of acetyl CoA: recombinant glutathione S-transferase 3-3 is acetylated by a novel membrane-bound transacetylase using 7,8-diacetoxy-4-methyl coumarin as the acetyl donor.
FEBS letters 2002;530(1-3):139-42.
2002: Ranju Kumari; Ekta Kohli; Garima Gupta; Hanumantharao G Raj; Virinder S Parmar; Giridhari Pal; Yogesh K Tyagi; Subhash C Jain; Carl E Olsen
Microsomal acetoxy drug: protein transacetylase of placenta: part 1. Characterization of DAMC: GST transacetylase.
Placenta 2002;23(4):352-7.
2001: Hanumantharao G Raj; Ekta Kohli; Vishwajeet Rohil; Bilikere S Dwarakanath; Virinder S Parmar; S Malik; Jawahar S Adhikari; Yogesh K Tyagi; Sanjay Goel; K Gupta; Mridula Bose; Carl E Olsen
Acetoxy-4-methylcoumarins confer differential protection from aflatoxin B(1)-induced micronuclei and apoptosis in lung and bone marrow cells.
Mutation research 2001;494(1-2):31-40.
2001: Hanumantharao G Raj; S Malik; Virinder S Parmar; Ekta Kohli; Yogesh K Tyagi; Vishwajeet Rohil; Bilikere S Dwarakanath; Jawahar S Adhikari; Mridula Bose; Subhash C Jain; Carl E Olsen
Chemoprevention of benzene-induced bone marrow and pulmonary genotoxicity.
Teratogenesis, carcinogenesis, and mutagenesis 2001;21(2):181-7.
2000: Hanumantharao G Raj; Virinder S Parmar; Subhash C Jain; Ekta Kohli; N Ahmad; Sanjay Goel; Yogesh K Tyagi; Sunil K Sharma; J Wengel; Carl E Olsen
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 7: Assay and characterization of 7,8-diacetoxy-4-methylcoumarin:protein transacetylase from rat liver microsomes based on the irreversible inhibition of cytosolic glutathione S-transferase.
Bioorganic & medicinal chemistry 2000;8(7):1707-12.
2000: H R Raj; Virinder S Parmar; Subhash C Jain; Sanjay Goel; Yogesh K Tyagi; S K Sharma; Carl E Olsen; J Wengel
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 6: hydrolysis of 7,8-diacetoxy-4-methylcoumarin by a novel deacetylase in rat liver microsomes--a simple method for assay and characterisation.
Bioorganic & medicinal chemistry 2000;8(1):233-7.
1999: Hanumantharao G Raj; Virinder S Parmar; Subhash C Jain; Sanjay Goel; Amarjit Singh; Yogesh K Tyagi; Hriday N Jha; Carl E Olsen; J Wengel
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 4: hyperbolic activation of rat liver microsomal NADPH-cytochrome C reductase by the novel acetylator 7,8-diacetoxy-4-methylcoumarin.
Bioorganic & medicinal chemistry 1999;7(2):369-73.
1998: Hanumantharao G Raj; R K Sharma; B S Garg; Virinder S Parmar; Subhash C Jain; Sanjay Goel; Yogesh K Tyagi; A Singh; Carl E Olsen; J Wengel
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 3: A novel mechanism for the inhibition of biological membrane lipid peroxidation by dioxygenated 4-methylcoumarins mediated by the formation of a stable ADP-Fe-inhibitor mixed ligand complex.
Bioorganic & medicinal chemistry 1998;6(11):2205-12.
1998: Hanumantharao G Raj; Virinder S Parmar; Subhash C Jain; Sanjay Goel; Amarjit Singh; K Gupta; Vishwajeet Rohil; Yogesh K Tyagi; Hriday N Jha; Carl E Olsen; J Wengel
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part II: Mechanism-based inhibition of rat liver microsome-mediated aflatoxin B1-DNA binding by the candidate antimutagen 7,8-diacetoxy-4-methylcoumarin.
Bioorganic & medicinal chemistry 1998;6(10):1895-904.