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Charles Tyler

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Yoshinao Katsu; Yukio Kawashima; Anke Lange; Shinichi Miyagawa; Norihisa Tatarazako; Charles R Tyler; Hiroshi Urushitani; Taisen Iguchi
Cloning, expression and functional characterization of carp, Cyprinus carpio, estrogen receptors and their differential activations by estrogens.
James E Cresswell; Natalie Hempel de Ibarra; Marie Holmbergh; Ian Laycock; Yueru Li; Christopher J Page; Christopher J Pook; Nick Smirnoff; Mehmet B Uygun; Jonathan G Wheeler; Charles R Tyler
Differential sensitivity of honey bees and bumble bees to a dietary insecticide (imidacloprid).
Fiona Larner; Jamie R Lead; Julian Moger; Luke J Bridgestock; Yuktee Dogra; Agnieszka Dybowska; Julia Fabrega; Tamara S Galloway; Rhys Goodhead; Björn Stolpe; Charles R Tyler; Eugenia Valsami-Jones; Dominik J Weiss; Mark Rehkämper
Tracing bioavailability of ZnO nanoparticles using stable isotope labeling.

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2013: Yoshinao Katsu; Yukio Kawashima; Anke Lange; Shinichi Miyagawa; Norihisa Tatarazako; Charles R Tyler; Hiroshi Urushitani; Taisen Iguchi
Cloning, expression and functional characterization of carp, Cyprinus carpio, estrogen receptors and their differential activations by estrogens.
Journal of applied toxicology : JAT 2013;33(1):41-9.
2012: James E Cresswell; Natalie Hempel de Ibarra; Marie Holmbergh; Ian Laycock; Yueru Li; Christopher J Page; Christopher J Pook; Nick Smirnoff; Mehmet B Uygun; Jonathan G Wheeler; Charles R Tyler
Differential sensitivity of honey bees and bumble bees to a dietary insecticide (imidacloprid).
Zoology (Jena, Germany) 2012;115(6):365-71.
2012: Fiona Larner; Jamie R Lead; Julian Moger; Luke J Bridgestock; Yuktee Dogra; Agnieszka Dybowska; Julia Fabrega; Tamara S Galloway; Rhys Goodhead; Björn Stolpe; Charles R Tyler; Eugenia Valsami-Jones; Dominik J Weiss; Mark Rehkämper
Tracing bioavailability of ZnO nanoparticles using stable isotope labeling.
Environmental science & technology 2012;46(21):12137-45.
2012: Marta Söffker; Jamie R Stevens; Charles R Tyler
Comparative breeding and behavioral responses to ethinylestradiol exposure in wild and laboratory maintained zebrafish (Danio rerio) populations.
Environmental science & technology 2012;46(20):11377-83.
2012: Marta Söffker; Charles R Tyler
Endocrine disrupting chemicals and sexual behaviors in fish--a critical review on effects and possible consequences.
Critical reviews in toxicology 2012;42(8):653-68.
2012: Raghad Al-Salhi; Anke Lange; Charles R Tyler; Alaa Abdul-Sada; Elizabeth Mary Hill
The xenometabolome and novel contaminant markers in fish exposed to a wastewater treatment works effluent.
Environmental science & technology 2012;46(16):9080-8.
2012: Okhyun Lee; Masazumi Tada; Aya Takesono; Charles R Tyler; Tetsuhiro Kudoh
Biosensor zebrafish provide new insights into potential health effects of environmental estrogens.
Environmental health perspectives 2012;120(7):990-6.
2012: Jenna Corcoran; Anke Lange; Matthew J Winter; Charles R Tyler
Effects of pharmaceuticals on the expression of genes involved in detoxification in a carp primary hepatocyte model.
Environmental science & technology 2012;46(11):6306-14.
2012: A Ross Brown; Patrick B Hamilton; Stewart F Owen; Gregory C Paull; Thomas A Ryan; Alan D Sharpe; Lisa K Bickley; Charles R Tyler
Differences in sexual development in inbred and outbred zebrafish (Danio rerio) and implications for chemical testing.
Aquatic toxicology (Amsterdam, Netherlands) 2012;112-113():27-38.
2012: Mohammed Baalousha; Paula A Cole; Teresa F Fernandes; Joseph A Hriljac; Mark A Jepson; Ian P Jones; Yon Ju-Nam; Vicki Stone; Charles R Tyler; Jamie R Lead
Characterization of cerium oxide nanoparticles-part 2: nonsize measurements.
Environmental toxicology and chemistry / SETAC 2012;31(5):994-1003.
2012: Mohammed Baalousha; Paula A Cole; Teresa F Fernandes; Birgit Gaiser; Joseph A Hriljac; Mark A Jepson; Yon Ju-Nam; Vicki Stone; Charles R Tyler; Jamie R Lead
Characterization of cerium oxide nanoparticles-part 1: size measurements.
Environmental toxicology and chemistry / SETAC 2012;31(5):983-93.
2012: Amy L Filby; Maren Ortiz-Zarragoitia; Gregory C Paull; Faye Searle; Charles R Tyler
Environmental estrogen-induced alterations of male aggression and dominance hierarchies in fish: a mechanistic analysis.
Environmental science & technology 2012;46(6):3472-9.
2012: Anke Lange; Shinichi Miyagawa; Masaki Nagae; Yukiko Ogino; Yuta Ohnishi; Yasuhiko Ohta; Tomohiro Oka; Jan A Shears; Norihisa Tatarazako; Charles R Tyler; Hiroshi Urushitani; Jun Yamamoto; Toshiaki Hirai; Yoshinao Katsu; Tohru Kobayashi; Taisen Iguchi
Comparative responsiveness to natural and synthetic estrogens of fish species commonly used in the laboratory and field monitoring.
Aquatic toxicology (Amsterdam, Netherlands) 2012;109():250-8.
2012: Julia Fabrega; Tony Fry; Aisha Amer; Jamie R Lead; Bjorn Stolpe; Ratna Tantra; Jordan Tomkins; Charles R Tyler; Tamara S Galloway
Sequestration of zinc from zinc oxide nanoparticles and life cycle effects in the sediment dweller amphipod Corophium volutator.
Environmental science & technology 2012;46(2):1128-35.
2012: Okhyun Lee; Charles R Tyler; Tetsuhiro Kudoh
Development of a transient expression assay for detecting environmental oestrogens in zebrafish and medaka embryos.
BMC biotechnology 2012;12():32.
2011: Marion Sebire; Nick G H Taylor; Ioanna Katsiadaki; Gerd Maack; Charles R Tyler
Short-term exposure to a treated sewage effluent alters reproductive behaviour in the three-spined stickleback (Gasterosteus aculeatus).
Aquatic toxicology (Amsterdam, Netherlands) 2011;105(1-2):78-88.
2011: Ángel García-López; María I Sánchez-Amaya; Charles R Tyler; Francisco Prat
Mechanisms of oocyte development in European sea bass (Dicentrarchus labrax L.): investigations via application of unilateral ovariectomy.
Reproduction (Cambridge, England) 2011;142(2):243-53.
2011: Andrew D Southam; Anke Lange; Adam Hines; Elizabeth Mary Hill; Yoshinao Katsu; Taisen Iguchi; Charles R Tyler; Mark R Viant
Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): implications for biomonitoring.
Environmental science & technology 2011;45(8):3759-67.
2011: Catherine A Harris; Patrick B Hamilton; Tamsin J Runnalls; Veronica Vinciotti; Alan Henshaw; Dave Hodgson; Tobias S Coe; Susan Jobling; Charles R Tyler; John P Sumpter
The consequences of feminization in breeding groups of wild fish.
Environmental health perspectives 2011;119(3):306-11.
2011: Anke Lange; Gregory C Paull; Patrick B Hamilton; Taisen Iguchi; Charles R Tyler
Implications of persistent exposure to treated wastewater effluent for breeding in wild roach (Rutilus rutilus) populations.
Environmental science & technology 2011;45(4):1673-9.
2011: Julia Fabrega; Samuel N Luoma; Charles R Tyler; Tamara S Galloway; Jamie R Lead
Silver nanoparticles: behaviour and effects in the aquatic environment.
Environment international 2011;37(2):517-31.
2010: Amy L Filby; Gregory C Paull; Emily J Bartlett; Katrien J W Van Look; Charles R Tyler
Physiological and health consequences of social status in zebrafish (Danio rerio).
Physiology & behavior 2010;101(5):576-87.
2010: Tobias S Coe; Marta K Söffker; Amy L Filby; David Hodgson; Charles R Tyler
Impacts of early life exposure to estrogen on subsequent breeding behavior and reproductive success in zebrafish.
Environmental science & technology 2010;44(16):6481-7.
2010: T M Scown; Ronny van Aerle; Charles R Tyler
Review: Do engineered nanoparticles pose a significant threat to the aquatic environment?
Critical reviews in toxicology 2010;40(7):653-70.
2010: Amy L Filby; Jan A Shears; Briane E Drage; John H Churchley; Charles R Tyler
Effects of advanced treatments of wastewater effluents on estrogenic and reproductive health impacts in fish.
Environmental science & technology 2010;44(11):4348-54.
2010: Tessa M Scown; Eduarda M Santos; Blair D Johnston; Birgit Gaiser; Mohammed Baalousha; Svetlin Mitov; Jamie R Lead; Vicki Stone; Teresa F Fernandes; Mark Jepson; Ronny van Aerle; Charles R Tyler
Effects of aqueous exposure to silver nanoparticles of different sizes in rainbow trout.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(2):521-34.
2010: Ioanna Katsiadaki; Tim Williams; Jonathan S Ball; Tim P Bean; Matthew B Sanders; Huifeng Wu; Eduarda M Santos; Margaret M Brown; Paul Baker; Fernando Ortega; Francesco Falciani; John A Craft; Charles R Tyler; Mark R Viant; James K Chipman
Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol.
Aquatic toxicology (Amsterdam, Netherlands) 2010;97(3):174-87.
2010: Jenna Corcoran; Matthew J Winter; Charles R Tyler
Pharmaceuticals in the aquatic environment: a critical review of the evidence for health effects in fish.
Critical reviews in toxicology 2010;40(4):287-304.
2010: Gregory C Paull; Amy L Filby; Hannah G Giddins; Tobias S Coe; Patrick B Hamilton; Charles R Tyler
Dominance hierarchies in zebrafish (Danio rerio) and their relationship with reproductive success.
Zebrafish 2010;7(1):109-17.
2010: Elizabeth Mary Hill; Kerry L Evans; Julia Horwood; Rostkowski Pawel; Francis Olumide Oladapo; Richard Gibson; Jan A Shears; Charles R Tyler
Profiles and some initial identifications of (anti)androgenic compounds in fish exposed to wastewater treatment works effluents.
Environmental science & technology 2010;44(3):1137-43.
2010: Blair D Johnston; Tessa M Scown; Julian Moger; Susan A Cumberland; Mohamed Baalousha; Kathryn Linge; Ronny van Aerle; Kym Jarvis; Jamie R Lead; Charles R Tyler
Bioavailability of nanoscale metal oxides TiO(2), CeO(2), and ZnO to fish.
Environmental science & technology 2010;44(3):1144-51.
2010: Eduarda M Santos; Jonathan S Ball; Tim Williams; Huifeng Wu; Fernando Ortega; Ronny van Aerle; Ioanna Katsiadaki; Francesco Falciani; Mark R Viant; James K Chipman; Charles R Tyler
Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model.
Environmental science & technology 2010;44(2):820-6.
2010: Amy L Filby; Gregory C Paull; Tamsin Fa Hickmore; Charles R Tyler
Unravelling the neurophysiological basis of aggression in a fish model.
BMC genomics 2010;11():498.
2009: A Ross Brown; David J Hosken; François Balloux; Lisa K Bickley; Gareth LePage; Stewart F Owen; Malcolm J Hetheridge; Charles R Tyler
Genetic variation, inbreeding and chemical exposure--combined effects in wildlife and critical considerations for ecotoxicology.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2009;364(1534):3377-90.
2009: Tobias S Coe; Patrick B Hamilton; David Hodgson; Gregory C Paull; Charles R Tyler
Parentage outcomes in response to estrogen exposure are modified by social grouping in zebrafish.
Environmental science & technology 2009;43(21):8400-5.
2009: L K Bickley; Anke Lange; M J Winter; Charles R Tyler
Evaluation of a carp primary hepatocyte culture system for screening chemicals for oestrogenic activity.
Aquatic toxicology (Amsterdam, Netherlands) 2009;94(3):195-203.
2009: Tim Williams; Huifeng Wu; Eduarda M Santos; Jon Ball; Ioanna Katsiadaki; Margaret M Brown; Paul Baker; Fernando Ortega; Francesco Falciani; John A Craft; Charles R Tyler; James K Chipman; Mark R Viant
Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene.
Environmental science & technology 2009;43(16):6341-8.
2009: Jörg Oehlmann; Ulrike Schulte-Oehlmann; Werner Kloas; Oana Jagnytsch; Ilka Lutz; Kresten O Kusk; Leah Wollenberger; Eduarda M Santos; Gregory C Paull; Katrien J W Van Look; Charles R Tyler
A critical analysis of the biological impacts of plasticizers on wildlife.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2009;364(1526):2047-62.
2009: Tessa M Scown; Ronny van Aerle; Blair D Johnston; Susan Cumberland; Jamie R Lead; Richard Owen; Charles R Tyler
High doses of intravenously administered titanium dioxide nanoparticles accumulate in the kidneys of rainbow trout but with no observable impairment of renal function.
Toxicological sciences : an official journal of the Society of Toxicology 2009;109(2):372-80.
2009: Charles R Tyler; Amy L Filby; Lisa K Bickley; Rob I Cumming; Richard Gibson; Pierre Labadie; Yoshinao Katsu; Katherine E Liney; Jan A Shears; Vanessa Silva-Castro; Hiroshi Urushitani; Anke Lange; Matthew J Winter; Taisen Iguchi; Elizabeth Mary Hill
Environmental health impacts of equine estrogens derived from hormone replacement therapy.
Environmental science & technology 2009;43(10):3897-904.
2009: Karen L Thorpe; Gerd Maack; Rachel Benstead; Charles R Tyler
Estrogenic wastewater treatment works effluents reduce egg production in fish.
Environmental science & technology 2009;43(8):2976-82.
2009: Anke Lange; Gregory C Paull; Tobias S Coe; Yoshinao Katsu; Hiroshi Urushitani; Taisen Iguchi; Charles R Tyler
Sexual reprogramming and estrogenic sensitization in wild fish exposed to ethinylestradiol.
Environmental science & technology 2009;43(4):1219-25.
2009: T S Coe; Patrick B Hamilton; A M Griffiths; D J Hodgson; M A Wahab; Charles R Tyler
Genetic variation in strains of zebrafish (Danio rerio) and the implications for ecotoxicology studies.
Ecotoxicology (London, England) 2009;18(1):144-50.
2008: Anke Lange; Yoshinao Katsu; Rie Ichikawa; Gregory C Paull; Laura L Chidgey; Tobias S Coe; Taisen Iguchi; Charles R Tyler
Altered sexual development in roach (Rutilus rutilus) exposed to environmental concentrations of the pharmaceutical 17alpha-ethinylestradiol and associated expression dynamics of aromatases and estrogen receptors.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(1):113-23.
2008: Karen L Thorpe; Rachel Benstead; Paul Eccles; Gerd Maack; Tim Williams; Charles R Tyler
A practicable laboratory flow-through exposure system for assessing the health effects of effluents in fish.
Aquatic toxicology (Amsterdam, Netherlands) 2008;88(3):164-72.
2008: Tobias S Coe; Patrick B Hamilton; David Hodgson; Gregory C Paull; Jamie R Stevens; Katie Sumner; Charles R Tyler
An environmental estrogen alters reproductive hierarchies, disrupting sexual selection in group-spawning fish.
Environmental science & technology 2008;42(13):5020-5.
2008: Gregory C Paull; Anke Lange; A C Henshaw; Charles R Tyler
Ontogeny of sexual development in the roach (Rutilus rutilus) and its interrelationships with growth and age.
Journal of morphology 2008;269(7):884-95.
2008: Gregory C Paull; Katrien J W Van Look; Eduarda M Santos; Amy L Filby; D Melati Gray; John P Nash; Charles R Tyler
Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals.
Aquatic toxicology (Amsterdam, Netherlands) 2008;87(2):115-26.
2008: Julian Moger; Blair D Johnston; Charles R Tyler
Imaging metal oxide nanoparticles in biological structures with CARS microscopy.
Optics express 2008;16(5):3408-19.
2008: Eduarda M Santos; Peter Kille; Victoria L Workman; Gregory C Paull; Charles R Tyler
Sexually dimorphic gene expression in the brains of mature zebrafish.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2008;149(3):314-24.
2008: Amy L Filby; Ronny van Aerle; JanWillem Duitman; Charles R Tyler
The kisspeptin/gonadotropin-releasing hormone pathway and molecular signaling of puberty in fish.
Biology of reproduction 2008;78(2):278-89.
2008: Ronny van Aerle; Peter Kille; A Lange; Charles R Tyler
Evidence for the existence of a functional Kiss1/Kiss1 receptor pathway in fish.
Peptides 2008;29(1):57-64.
2007: Karen L Thorpe; Rachel Benstead; Thomas H Hutchinson; Charles R Tyler
Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow (Pimephales promelas).
Aquatic toxicology (Amsterdam, Netherlands) 2007;85(3):176-83.
2007: Amy L Filby; Eduarda M Santos; Karen L Thorpe; Gerd Maack; Charles R Tyler
Gene expression profiling for understanding chemical causation of biological effects for complex mixtures: a case study on estrogens.
Environmental science & technology 2007;41(23):8187-94.
2007: Amy L Filby; Teresa Neuparth; Karen L Thorpe; Richard Owen; Tamara S Galloway; Charles R Tyler
Health impacts of estrogens in the environment, considering complex mixture effects.
Environmental health perspectives 2007;115(12):1704-10.
2007: Rudiger W Schulz; Jan Bogerd; Rune Male; Jonathan Ball; Martina Fenske; Lisbeth C Olsen; Charles R Tyler
Estrogen-induced alterations in amh and dmrt1 expression signal for disruption in male sexual development in the zebrafish.
Environmental science & technology 2007;41(17):6305-10.
2007: Eduarda M Santos; V L Workman; Gregory C Paull; Amy L Filby; Katrien J W Van Look; Peter Kille; Charles R Tyler
Molecular basis of sex and reproductive status in breeding zebrafish.
Physiological genomics 2007;30(2):111-22.
2007: Eduarda M Santos; Gregory C Paull; Katrien J W Van Look; Victoria L Workman; William V Holt; Ronny van Aerle; Peter Kille; Charles R Tyler
Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio).
Aquatic toxicology (Amsterdam, Netherlands) 2007;83(2):134-42.
2007: Yoshinao Katsu; Anke Lange; Hiroshi Urushitani; Rie Ichikawa; Gregory C Paull; Laura L Cahill; Susan Jobling; Charles R Tyler; Taisen Iguchi
Functional associations between two estrogen receptors, environmental estrogens, and sexual disruption in the roach (Rutilus rutilus).
Environmental science & technology 2007;41(9):3368-74.
2007: Amy L Filby; Karen L Thorpe; Gerd Maack; Charles R Tyler
Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish.
Aquatic toxicology (Amsterdam, Netherlands) 2007;81(2):219-31.
2007: Karen L Thorpe; Rachel Benstead; Thomas H Hutchinson; Charles R Tyler
An optimised experimental test procedure for measuring chemical effects on reproduction in the fathead minnow, Pimephales promelas.
Aquatic toxicology (Amsterdam, Netherlands) 2007;81(1):90-8.
2007: Charles R Tyler; Anke Lange; Gregory C Paull; Yoshinao Katsu; Taisen Iguchi
The roach (Rutilus rutilus) as a sentinel for assessing endocrine disruption.
Environmental sciences : an international journal of environmental physiology and toxicology 2007;14(5):235-53.
2007: Hiroshi Urushitani; Yoshinao Katsu; Yasuhiko Kato; Osamu Tooi; Noriaki Santo; Yukio Kawashima; Yasuhiko Ohta; Yumi Kisaka; Anke Lange; Charles R Tyler; Rodney D Johnson; Taisen Iguchi
Medaka (Oryzias latipes) for use in evaluating developmental effects of endocrine active chemicals with special reference to gonadal intersex (testis-ova).
Environmental sciences : an international journal of environmental physiology and toxicology 2007;14(5):211-33.
2007: Amy L Filby; Charles R Tyler
Appropriate 'housekeeping' genes for use in expression profiling the effects of environmental estrogens in fish.
BMC molecular biology 2007;8():10.
2007: Amy L Filby; Charles R Tyler
Cloning and characterization of cDNAs for hormones and/or receptors of growth hormone, insulin-like growth factor-I, thyroid hormone, and corticosteroid and the gender-, tissue-, and developmental-specific expression of their mRNA transcripts in fathead minnow (Pimephales promelas).
General and comparative endocrinology 2007;150(1):151-63.
2006: Amy L Filby; Karen L Thorpe; Charles R Tyler
Multiple molecular effect pathways of an environmental oestrogen in fish.
Journal of molecular endocrinology 2006;37(1):121-34.
2006: Grace H Panter; Thomas H Hutchinson; KS Hurd; J Bamforth; R D Stanley; S Duffell; A Hargreaves; S Gimeno; Charles R Tyler
Development of chronic tests for endocrine active chemicals. Part 1. An extended fish early-life stage test for oestrogenic active chemicals in the fathead minnow (Pimephales promelas).
Aquatic toxicology (Amsterdam, Netherlands) 2006;77(3):279-90.
2006: Thomas H Hutchinson; Gerald T Ankley; Helmut Segner; Charles R Tyler
Screening and testing for endocrine disruption in fish-biomarkers as "signposts," not "traffic lights," in risk assessment.
Environmental health perspectives 2006;114 Suppl 1():106-14.
2006: Karen L Thorpe; Melanie Gross-Sorokin; Ian Johnson; Geoff Brighty; Charles R Tyler
An assessment of the model of concentration addition for predicting the estrogenic activity of chemical mixtures in wastewater treatment works effluents.
Environmental health perspectives 2006;114 Suppl 1():90-7.
2006: Katherine E Liney; Josephine A Hagger; Charles R Tyler; Michael H Depledge; Tamara S Galloway; Susan Jobling
Health effects in fish of long-term exposure to effluents from wastewater treatment works.
Environmental health perspectives 2006;114 Suppl 1():81-9.
2006: Susan Jobling; Richard Williams; Andrew Johnson; Ayesha Taylor; Melanie Gross-Sorokin; Monique Nolan; Charles R Tyler; Ronny van Aerle; Eduarda Santos; Geoff Brighty
Predicted exposures to steroid estrogens in U.K. rivers correlate with widespread sexual disruption in wild fish populations.
Environmental health perspectives 2006;114 Suppl 1():32-9.
2006: Susan Jobling; Charles R Tyler
Introduction: The ecological relevance of chemically induced endocrine disruption in wildlife.
Environmental health perspectives 2006;114 Suppl 1():7-8.
2005: Katherine E Liney; Susan Jobling; Jan A Shears; Peter Simpson; Charles R Tyler
Assessing the sensitivity of different life stages for sexual disruption in roach (Rutilus rutilus) exposed to effluents from wastewater treatment works.
Environmental health perspectives 2005;113(10):1299-307.
2005: Amy L Filby; Charles R Tyler
Molecular characterization of estrogen receptors 1, 2a, and 2b and their tissue and ontogenic expression profiles in fathead minnow (Pimephales promelas).
Biology of reproduction 2005;73(4):648-62.
2005: Emma Vine; Jan A Shears; Ronny van Aerle; Charles R Tyler; John P Sumpter
Endocrine (sexual) disruption is not a prominent feature in the pike (Esox lucius), a top predator, living in English waters.
Environmental toxicology and chemistry / SETAC 2005;24(6):1436-43.
2005: Charles R Tyler; C Spary; R Gibson; Eduarda M Santos; Jan A Shears; Elizabeth Mary Hill
Accounting for differences in estrogenic responses in rainbow trout (Oncorhynchus mykiss: Salmonidae) and roach (Rutilus rutilus: Cyprinidae) exposed to effluents from wastewater treatment works.
Environmental science & technology 2005;39(8):2599-607.
2004: Jon P Nash; David E Kime; Leo T M van der Ven; Piet W Wester; François Brion; Gerd Maack; Petra Stahlschmidt-Allner; Charles R Tyler
Long-term exposure to environmental concentrations of the pharmaceutical ethynylestradiol causes reproductive failure in fish.
Environmental health perspectives 2004;112(17):1725-33.
2004: Grace H Panter; Thomas H Hutchinson; KS Hurd; A Sherren; R D Stanley; Charles R Tyler
Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows (Pimephales promelas) using easily measured endpoints of sexual development.
Aquatic toxicology (Amsterdam, Netherlands) 2004;70(1):11-21.
2004: Charles R Tyler; Ronny van Aerle; Eduarda M Santos
ELISAs for detecting vitellogenin in the fathead minnow (Pimephales promelas)-a critical analysis. Response to Mylchreest et al., Comp Biochem Physiol C 134: 251-257, 2003.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2004;138(4):531-2; author reply 533-6.
2004: Sascha Pawlowski; A Sauer; Jan A Shears; Charles R Tyler; Thomas Braunbeck
Androgenic and estrogenic effects of the synthetic androgen 17alpha-methyltestosterone on sexual development and reproductive performance in the fathead minnow (Pimephales promelas) determined using the gonadal recrudescence assay.
Aquatic toxicology (Amsterdam, Netherlands) 2004;68(3):277-91.
2004: Laura Spanò; Charles R Tyler; Ronny van Aerle; Pierre Devos; S N M Mandiki; Frédéric Silvestre; Jean-Pierre Thomé; Patrick Kestemont
Effects of atrazine on sex steroid dynamics, plasma vitellogenin concentration and gonad development in adult goldfish (Carassius auratus).
Aquatic toxicology (Amsterdam, Netherlands) 2004;66(4):369-79.
2004: Sascha Pawlowski; Ronny van Aerle; Charles R Tyler; Thomas Braunbeck
Effects of 17alpha-ethinylestradiol in a fathead minnow (Pimephales promelas) gonadal recrudescence assay.
Ecotoxicology and environmental safety 2004;57(3):330-45.
2004: Susan Jobling; D Casey; T Rogers-Gray; Jörg Oehlmann; Ulrike Schulte-Oehlmann; Sascha Pawlowski; T Baunbeck; A P Turner; Charles R Tyler
Comparative responses of molluscs and fish to environmental estrogens and an estrogenic effluent.
Aquatic toxicology (Amsterdam, Netherlands) 2004;66(2):207-22.
2003: Karen A Pickford; R Emma Thomas-Jones; Brian Wheals; Charles R Tyler; John P Sumpter
Route of exposure affects the oestrogenic response of fish to 4-tert-nonylphenol.
Aquatic toxicology (Amsterdam, Netherlands) 2003;65(3):267-79.
2003: Susan Jobling; D Casey; TP Rodgers-Gray; Jörg Oehlmann; Ulrike Schulte-Oehlmann; Sascha Pawlowski; T Baunbeck; A P Turner; Charles R Tyler
Comparative responses of molluscs and fish to environmental estrogens and an estrogenic effluent.
Aquatic toxicology (Amsterdam, Netherlands) 2003;65(2):205-20.
2003: Karen L Thorpe; Rob I Cummings; Thomas H Hutchinson; Martin Scholze; Geoff Brighty; John P Sumpter; Charles R Tyler
Relative potencies and combination effects of steroidal estrogens in fish.
Environmental science & technology 2003;37(6):1142-9.
2003: S Halm; J Y Kwon; Mariann Rand-Weaver; John P Sumpter; Nadine A Pounds; Thomas H Hutchinson; Charles R Tyler
Cloning and gene expression of P450 17alpha-hydroxylase,17,20-lyase cDNA in the gonads and brain of the fathead minnow Pimephales promelas.
General and comparative endocrinology 2003;130(3):256-66.
2003: Susan Jobling; Charles R Tyler
Endocrine disruption, parasites and pollutants in wild freshwater fish.
Parasitology 2003;126 Suppl():S103-8.
2002: Ronny van Aerle; Nadine A Pounds; Thomas H Hutchinson; Sue Maddix; Charles R Tyler
Window of sensitivity for the estrogenic effects of ethinylestradiol in early life-stages of fathead minnow, Pimephales promelas.
Ecotoxicology (London, England) 2002;11(6):423-34.
2002: S Halm; Nadine A Pounds; Sue Maddix; Mariann Rand-Weaver; John P Sumpter; Thomas H Hutchinson; Charles R Tyler
Exposure to exogenous 17beta-oestradiol disrupts p450aromB mRNA expression in the brain and gonad of adult fathead minnows (Pimephales promelas).
Aquatic toxicology (Amsterdam, Netherlands) 2002;60(3-4):285-99.
2002: Susan Jobling; S Coey; J G Whitmore; David E Kime; Katrien J W Van Look; Brian G McAllister; NA Beresford; A C Henshaw; Geoff Brighty; Charles R Tyler; John P Sumpter
Wild intersex roach (Rutilus rutilus) have reduced fertility.
Biology of reproduction 2002;67(2):515-24.
2002: Markus Hecker; Charles R Tyler; Mervée Hoffmann; Sue Maddix; Ludwig Karbe
Plasma biomarkers in fish provide evidence for endocrine modulation in the Elbe River, Germany.
Environmental science & technology 2002;36(11):2311-21.
2002: Lucy A Kirk; Charles R Tyler; Christina M Lye; John P Sumpter
Changes in estrogenic and androgenic activities at different stages of treatment in wastewater treatment works.
Environmental toxicology and chemistry / SETAC 2002;21(5):972-9.
2002: Grace H Panter; Thomas H Hutchinson; Reinhard Länge; Christina M Lye; John P Sumpter; Melanie Zerulla; Charles R Tyler
Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.
Environmental toxicology and chemistry / SETAC 2002;21(2):319-26.
2002: Susan Jobling; NA Beresford; M Nolan; TP Rodgers-Gray; Geoff Brighty; John P Sumpter; Charles R Tyler
Altered sexual maturation and gamete production in wild roach (Rutilus rutilus) living in rivers that receive treated sewage effluents.
Biology of reproduction 2002;66(2):272-81.
2002: Charles R Tyler; Ronny van Aerle; Mona V Nilsen; Robert Blackwell; Sue Maddix; Bente M Nilsen; Karin Berg; Thomas H Hutchinson; Anders Goksøyr
Monoclonal antibody enzyme-linked immunosorbent assay to quantify vitellogenin for studies on environmental estrogens in the rainbow trout (Oncorhynchus mykiss).
Environmental toxicology and chemistry / SETAC 2002;21(1):47-54.
2001: Ronny van Aerle; T M Nolan; Susan Jobling; L B Christiansen; John P Sumpter; Charles R Tyler
Sexual disruption in a second species of wild cyprinid fish (the gudgeon, Gobio gobio) in United Kingdom freshwaters.
Environmental toxicology and chemistry / SETAC 2001;20(12):2841-7.
2001: J Y Kwon; F Prat; C Randall; Charles R Tyler
Molecular characterization of putative yolk processing enzymes and their expression during oogenesis and embryogenesis in rainbow trout (Oncorhynchus mykiss).
Biology of reproduction 2001;65(6):1701-9.
2001: P Sohoni; Charles R Tyler; KS Hurd; J Caunter; Malcolm J Hetheridge; T Williams; C Woods; M Evans; R Toy; M Gargas; John P Sumpter
Reproductive effects of long-term exposure to Bisphenol A in the fathead minnow (Pimephales promelas).
Environmental science & technology 2001;35(14):2917-25.
2001: Catherine A Harris; Eduarda M Santos; A Janbakhsh; Tom G Pottinger; Charles R Tyler; John P Sumpter
Nonylphenol affects gonadotropin levels in the pituitary gland and plasma of female rainbow trout.
Environmental science & technology 2001;35(14):2909-16.
2001: Martina Fenske; Ronny van Aerle; S Brack; Charles R Tyler; Helmut Segner
Development and validation of a homologous zebrafish (Danio rerio Hamilton-Buchanan) vitellogenin enzyme-linked immunosorbent assay (ELISA) and its application for studies on estrogenic chemicals.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2001;129(3):217-32.
2001: Eduarda M Santos; Mariann Rand-Weaver; Charles R Tyler
Follicle-stimulating hormone and its alpha and beta subunits in rainbow trout (Oncorhynchus mykiss): purification, characterization, development of specific radioimmunoassays, and their seasonal plasma and pituitary concentrations in females.
Biology of reproduction 2001;65(1):288-94.
2001: Karen L Thorpe; Thomas H Hutchinson; Malcolm J Hetheridge; Martin Scholze; John P Sumpter; Charles R Tyler
Assessing the biological potency of binary mixtures of environmental estrogens using vitellogenin induction in juvenile rainbow trout (Oncorhynchus mykiss).
Environmental science & technology 2001;35(12):2476-81.
2001: Rüdiger W Schulz; Henry Vischer; JE Cavaco; Eduarda M Santos; Charles R Tyler; H J Th Goos; Jan Bogerd
Gonadotropins, their receptors, and the regulation of testicular functions in fish.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2001;129(2-3):407-17.
2001: TP Rodgers-Gray; Susan Jobling; C Kelly; Steven Morris; Geoff Brighty; Michael J Waldock; John P Sumpter; Charles R Tyler
Exposure of juvenile roach (Rutilus rutilus) to treated sewage effluent induces dose-dependent and persistent disruption in gonadal duct development.
Environmental science & technology 2001;35(3):462-70.
2000: A Bhaskaran; D May; Mariann Rand-Weaver; Charles R Tyler
Molecular characterization of the first non-mammalian p73 cDNA.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2000;126(1):49-57.
1999: L M Perazzolo; K Coward; Blandine Davail; E Normand; Charles R Tyler; F Pakdel; Wolfgang J Schneider; Françoise Le Menn
Expression and localization of messenger ribonucleic acid for the vitellogenin receptor in ovarian follicles throughout oogenesis in the rainbow trout, Oncorhynchus mykiss.
Biology of reproduction 1999;60(5):1057-68.
1999: A Bhaskaran; D May; Mariann Rand-Weaver; Charles R Tyler
Fish p53 as a possible biomarker for genotoxins in the aquatic environment.
Environmental and molecular mutagenesis 1999;33(3):177-84.
1998: Charles R Tyler; Susan Jobling; John P Sumpter
Endocrine disruption in wildlife: a critical review of the evidence.
Critical reviews in toxicology 1998;28(4):319-61.
1998: F Prat; K Coward; John P Sumpter; Charles R Tyler
Molecular characterization and expression of two ovarian lipoprotein receptors in the rainbow trout, Oncorhynchus mykiss.
Biology of reproduction 1998;58(5):1146-53.
1997: S Brooks; Charles R Tyler; Oliana Carnevali; K Coward; John P Sumpter
Molecular characterisation of ovarian cathepsin D in the rainbow trout, Oncorhynchus mykiss.
Gene 1997;201(1-2):45-54.
1997: Charles R Tyler; Tom G Pottinger; K Coward; F Prat; NA Beresford; Sue Maddix
Salmonid follicle-stimulating hormone (GtH I) mediates vitellogenic development of oocytes in the rainbow trout, Oncorhynchus mykiss.
Biology of reproduction 1997;57(5):1238-44.
1996: F Prat; John P Sumpter; Charles R Tyler
Validation of radioimmunoassays for two salmon gonadotropins (GTH I and GTH II) and their plasma concentrations throughout the reproductivecycle in male and female rainbow trout (Oncorhynchus mykiss).
Biology of reproduction 1996;54(6):1375-82.
1996: Charles R Tyler; Tom G Pottinger; E Santos; John P Sumpter; S A Price; S Brooks; J J Nagler
Mechanisms controlling egg size and number in the rainbow trout, Oncorhynchus mykiss.
Biology of reproduction 1996;54(1):8-15.
1996: Charles R Tyler; K Lubberink
Identification of four ovarian receptor proteins that bind vitellogenin but not other homologous plasma lipoproteins in the rainbow trout, Oncorhynchus mykiss.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 1996;166(1):11-20.
1991: Charles R Tyler; John P Sumpter; H Kawauchi; P Swanson
Involvement of gonadotropin in the uptake of vitellogenin into vitellogenic oocytes of the rainbow trout, Oncorhynchus mykiss.
General and comparative endocrinology 1991;84(2):291-9.
1990: Charles R Tyler; John P Sumpter; P R Witthames
The dynamics of oocyte growth during vitellogenesis in the rainbow trout (Oncorhynchus mykiss).
Biology of reproduction 1990;43(2):202-9.