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George Tzanakakis

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P G Dedes; Ch Gialeli; Ioannis Kanakis; Dimitris Kletsas; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease.
Ch Gialeli; Dimitris Kletsas; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.
Christina J Malavaki; Andreas E Roussidis; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Chrisostomi Gialeli; Dimitris Kletsas; Nikos Karamanos
Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells.

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2013: P G Dedes; Ch Gialeli; Ioannis Kanakis; Dimitris Kletsas; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease.
Biochimica et biophysica acta 2013;1830(6):3625-34.
2013: Ch Gialeli; Dimitris Kletsas; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.
Investigational new drugs 2013;31(3):516-24.
2013: Christina J Malavaki; Andreas E Roussidis; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Chrisostomi Gialeli; Dimitris Kletsas; Nikos Karamanos
Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells.
The FEBS journal 2013;280(10):2477-89.
2013: Anastasios I Tsonis; George N Tzanakakis; Zoi Piperigkou; Spyros S Skandalis; Achilleas D Theocharis; Nikolaos Afratis; Maria-Ioanna Ellina; Chrisostomi Gialeli; Nikos Karamanos
Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells.
The FEBS journal 2013;280(10):2248-59.
2013: Maria Mytilinaiou; Dragana Nikitovic; Kallirroi Voudouri; Artan Bano; Aikaterini Berdiaki; Alexandra Kalogeraki; Nikos Karamanos; George N Tzanakakis
Syndecan-2 is a key regulator of transforming growth factor beta 2/Smad2-mediated adhesion in fibrosarcoma cells.
IUBMB life 2013;65(2):134-43.
2012: P G Dedes; Ch Gialeli; Ioannis Kanakis; Dimitris Kletsas; Achilleas D Theocharis; A I Tsonis; George N Tzanakakis; Nikos Karamanos
Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid.
Biochimica et biophysica acta 2012;1820(12):1926-39.
2012: Dragana Nikitovic; John Aggelidakis; Renato V Iozzo; Nikos Karamanos; Marian F Young; George N Tzanakakis
The biology of small leucine-rich proteoglycans in bone pathophysiology.
The Journal of biological chemistry 2012;287(41):33926-33.
2012: Spyros S Skandalis; Achilleas D Theocharis; George N Tzanakakis; N Afratis; A J Aletras; C Gialeli; Nikos Karamanos
Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules.
Current molecular medicine 2012;12(8):1068-82.
2012: Nikos Afratis; Chrisostomi Gialeli; Evgenia Karousou; Dragana Nikitovic; Mauro S Pavão; Achilleas D Theocharis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Glycosaminoglycans: key players in cancer cell biology and treatment.
The FEBS journal 2012;279(7):1177-97.
2012: Nikos Karamanos; George N Tzanakakis
Glycosaminoglycans: from "cellular glue" to novel therapeutical agents.
Current opinion in pharmacology 2012;12(2):220-2.
2012: Dragana Nikitovic; A Tsatsakis; John Tsiaoussis; G Chatzinikolaou; Nikos Karamanos; George N Tzanakakis
Insights into targeting colon cancer cell fate at the level of proteoglycans / glycosaminoglycans.
Current medicinal chemistry 2012;19(25):4247-58.
2011: Georgia Chalkiadaki; Nikos Karamanos; Pavlos Katonis; Ioanna Kotsikogianni; Dragana Nikitovic; Aristidis Tsatsakis; Aikaterini Berdiaki; George N Tzanakakis
Low molecular weight heparin inhibits melanoma cell adhesion and migration through a PKCa/JNK signaling pathway inducing actin cytoskeleton changes.
Cancer letters 2011;312(2):235-44.
2011: Katerina Kouvidi; Dragana Nikitovic; Nikos Afratis; Aikaterini Berdiaki; Vincent C Hascall; Nikos Karamanos; Pavlos Katonis; George N Tzanakakis
Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion.
The Journal of biological chemistry 2011;286(44):38509-20.
2011: Georgios A Datsis; Nikos Karamanos; Pavlos Katonis; Maria Mytilineou; Dragana Nikitovic; Aikaterini Berdiaki; George N Tzanakakis
Parathyroid hormone affects the fibroblast growth factor-proteoglycan signaling axis to regulate osteosarcoma cell migration.
The FEBS journal 2011;278(19):3782-92.
2011: Dragana Nikitovic; Georgia Chalkiadaki; Aikaterini Berdiaki; John Aggelidakis; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Lumican regulates osteosarcoma cell adhesion by modulating TGFβ2 activity.
The international journal of biochemistry & cell biology 2011;43(6):928-35.
2011: Konstantin Krasagakis; Irene Fragiadaki; Maria Metaxari; Sabine Krüger-Krasagakis; George N Tzanakakis; Efstathios N Stathopoulos; Jürgen Eberle; Nektarios Tavernarakis; Androniki Tosca
KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitro.
Journal of cellular physiology 2011;226(4):1099-109.
2011: Georgia Chalkiadaki; Dragana Nikitovic; Aikaterini Berdiaki; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Heparin plays a key regulatory role via a p53/FAK-dependent signaling in melanoma cell adhesion and migration.
IUBMB life 2011;63(2):109-19.
2011: Fang Zong; David Brodin; Eleni Fthenou; Anders Hjerpe; ilona kovalszky; Filip Mundt; Tünde Szatmári; László Szilák; George N Tzanakakis; Katalin Dobra
Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration.
PloS one 2011;6(6):e14816.
2011: Christina J Malavaki; Achilleas D Theocharis; Fotini N Lamari; Ioannis Kanakis; Theodore Tsegenidis; George N Tzanakakis; Nikos Karamanos
Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization.
Biomedical chromatography : BMC 2011;25(1-2):11-20.
2010: Achilleas D Theocharis; Spyros S Skandalis; George N Tzanakakis; Nikos Karamanos
Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting.
The FEBS journal 2010;277(19):3904-23.
2010: Alexandros Zafiropoulos; Manolis Linardakis; Eugene H J M Jansen; Aristidis M Tsatsakis; Antonis Kafatos; George N Tzanakakis
Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue.
Journal of lipid research 2010;51(7):1991-2000.
2010: G Chatzinikolaou; Dragana Nikitovic; A Berdiaki; Alexandros Zafiropoulos; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Heparin regulates colon cancer cell growth through p38 mitogen-activated protein kinase signalling.
Cell proliferation 2010;43(1):9-18.
2010: F Zong; E Fthenou; J Castro; B Péterfia; ilona kovalszky; László Szilák; George N Tzanakakis; Katalin Dobra
Effect of syndecan-1 overexpression on mesenchymal tumour cell proliferation with focus on different functional domains.
Cell proliferation 2010;43(1):29-40.
2009: Aikaterini Berdiaki; Dragana Nikitovic; Aristidis M Tsatsakis; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells.
Biochimica et biophysica acta 2009;1790(10):1258-65.
2009: Georgia Chalkiadaki; Dragana Nikitovic; Aikaterini Berdiaki; Maria Sifaki; Konstantin Krasagakis; Pavlos Katonis; Nikos Karamanos; George N Tzanakakis
Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism.
The international journal of biochemistry & cell biology 2009;41(6):1323-31.
2009: Aristidis M Tsatsakis; Alexandros Zafiropoulos; Manolis N Tzatzarakis; George N Tzanakakis; Anthony Kafatos
Relation of PON1 and CYP1A1 genetic polymorphisms to clinical findings in a cross-sectional study of a Greek rural population professionally exposed to pesticides.
Toxicology letters 2009;186(1):66-72.
2009: Fang Zong; Eleni Fthenou; Nina Wolmer; Péter Hollósi; ilona kovalszky; László Szilák; Carolin Mogler; Gustav Nilsonne; George N Tzanakakis; Katalin Dobra
Syndecan-1 and FGF-2, but not FGF receptor-1, share a common transport route and co-localize with heparanase in the nuclei of mesenchymal tumor cells.
PloS one 2009;4(10):e7346.
2009: Ch Gialeli; Dimitris Kletsas; D Mavroudis; Haralabos P Kalofonos; George N Tzanakakis; Nikos Karamanos
Targeting epidermal growth factor receptor in solid tumors: critical evaluation of the biological importance of therapeutic monoclonal antibodies.
Current medicinal chemistry 2009;16(29):3797-804.
2009: Eleni Fthenou; Fang Zong; Alexandros Zafiropoulos; Katalin Dobra; Anders Hjerpe; George N Tzanakakis
Chondroitin sulfate A regulates fibrosarcoma cell adhesion, motility and migration through JNK and tyrosine kinase signaling pathways.
In vivo (Athens, Greece) 2009;23(1):69-76.
2008: Dragana Nikitovic; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Lumican, a small leucine-rich proteoglycan.
IUBMB life 2008;60(12):818-23.
2008: Olga Ch Kousidou; Aikaterini Berdiaki; Dimitris Kletsas; Alexandros Zafiropoulos; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Estradiol-estrogen receptor: a key interplay of the expression of syndecan-2 and metalloproteinase-9 in breast cancer cells.
Molecular oncology 2008;2(3):223-32.
2008: Konstantin Krasagakis; Sabine Krüger-Krasagakis; George N Tzanakakis; Katherine Darivianaki; Efstathios N Stathopoulos; Androniki Tosca
Interferon-alpha inhibits proliferation and induces apoptosis of merkel cell carcinoma in vitro.
Cancer investigation 2008;26(6):562-8.
2008: Athanasia P Asimakopoulou; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents.
In vivo (Athens, Greece) 2008;22(3):385-9.
2008: Pavlos Katonis; A Papoutsidakis; Agisilaos Aligizakis; George N Tzanakakis; George M Kontakis; Panayiotis Papagelopoulos
Mechanoreceptors of the posterior cruciate ligament.
The Journal of international medical research 2008;36(3):387-93.
2008: Alexandros Zafiropoulos; Dragana Nikitovic; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Decorin-induced growth inhibition is overcome through protracted expression and activation of epidermal growth factor receptors in osteosarcoma cells.
Molecular cancer research : MCR 2008;6(5):785-94.
2008: Georgia Chatzinikolaou; Dragana Nikitovic; Athanasia Asimakopoulou; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Heparin--a unique stimulator of human colon cancer cells' growth.
IUBMB life 2008;60(5):333-40.
2008: E Fthenou; Alexandros Zafiropoulos; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Chondroitin sulfate prevents platelet derived growth factor-mediated phosphorylation of PDGF-Rbeta in normal human fibroblasts severely impairing mitogenic responses.
Journal of cellular biochemistry 2008;103(6):1866-76.
2008: Ioannis K Kostakis; Nicole Pouli; Panagiotis Marakos; Olga Ch Kousidou; Andreas Roussidis; George N Tzanakakis; Nikos Karamanos
Design, synthesis and cell growth inhibitory activity of a series of novel aminosubstituted xantheno[1,2-d]imidazoles in breast cancer cells.
Bioorganic & medicinal chemistry 2008;16(6):3445-55.
2008: Christina J Malavaki; Athanasia P Asimakopoulou; Fotini N Lamari; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
Capillary electrophoresis for the quality control of chondroitin sulfates in raw materials and formulations.
Analytical biochemistry 2008;374(1):213-20.
2008: A Berdiaki; Alexandros Zafiropoulos; E Fthenou; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Regulation of hyaluronan and versican deposition by growth factors in fibrosarcoma cell lines.
Biochimica et biophysica acta 2008;1780(2):194-202.
2008: Alexandros Zafiropoulos; George N Tzanakakis
Decorin-mediated effects in cancer cell biology.
Connective tissue research 2008;49(3):244-8.
2008: Dragana Nikitovic; Katerina Berdiaki; Georgia Chalkiadaki; Nikos Karamanos; George N Tzanakakis
The role of SLRP-proteoglycans in osteosarcoma pathogenesis.
Connective tissue research 2008;49(3):235-8.
2008: Xanthi N Stahtea; Olga Ch Kousidou; Andreas E Roussidis; George N Tzanakakis; Nikos Karamanos
Small tyrosine kinase inhibitors as key molecules in the expression of metalloproteinases by solid tumors.
Connective tissue research 2008;49(3):211-4.
2008: Alexandros Zafiropoulos; Eleni Fthenou; Georgia Chatzinikolaou; George N Tzanakakis
Glycosaminoglycans and PDGF signaling in mesenchymal cells.
Connective tissue research 2008;49(3):153-6.
2008: Dragana Nikitovic; Aikaterini Berdiaki; Alexandros Zafiropoulos; Pavlos Katonis; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells.
The FEBS journal 2008;275(2):350-61.
2008: Dragana Nikitovic; M Assouti; M Sifaki; Pavlos Katonis; Konstantin Krasagakis; Nikos Karamanos; George N Tzanakakis
Chondroitin sulfate and heparan sulfate-containing proteoglycans are both partners and targets of basic fibroblast growth factor-mediated proliferation in human metastatic melanoma cell lines.
The international journal of biochemistry & cell biology 2008;40(1):72-83.
2007: Xanthi N Stahtea; Andreas E Roussidis; Ioannis Kanakis; George N Tzanakakis; george chalkiadakis; Dimitris Mavroudis; Dimitris Kletsas; Nikos Karamanos
Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation.
International journal of cancer. Journal international du cancer 2007;121(12):2808-14.
2007: G Chatzinikolaou; Dragana Nikitovic; Efstathios N Stathopoulos; G A Velegrakis; Nikos Karamanos; George N Tzanakakis
Protein tyrosine kinase and estrogen receptor-dependent pathways regulate the synthesis and distribution of glycosaminoglycans/proteoglycans produced by two human colon cancer cell lines.
Anticancer research 2007;27(6B):4101-6.
2007: Vasiliki Giannouli; Ioannis K Kostakis; Nicole Pouli; Panagiotis Marakos; Olga Ch Kousidou; George N Tzanakakis; Nikos Karamanos
Design, synthesis, and evaluation of the antiproliferative activity of a series of novel fused xanthenone aminoderivatives in human breast cancer cells.
Journal of medicinal chemistry 2007;50(7):1716-9.
2007: George N Tzanakakis; Dragana Nikitovic; Pavlos Katonis; Ioannis Kanakis; Nikos Karamanos
Expression and distribution of N-acetyl and N-glycolylneuraminic acids in secreted and cell-associated glycoconjugates by two human osteosarcoma cell lines.
Biomedical chromatography : BMC 2007;21(4):406-9.
2007: George Kolokythas; Ioannis K Kostakis; Nicole Pouli; Panagiotis Marakos; Olga Ch Kousidou; George N Tzanakakis; Nikos Karamanos
Design and synthesis of new pyranoxanthenones bearing a nitro group or an aminosubstituted side chain on the pyran ring. Evaluation of their growth inhibitory activity in breast cancer cells.
European journal of medicinal chemistry 2007;42(3):307-19.
2007: Andreas E Roussidis; Achilleas D Theocharis; George N Tzanakakis; Nikos Karamanos
The importance of c-Kit and PDGF receptors as potential targets for molecular therapy in breast cancer.
Current medicinal chemistry 2007;14(7):735-43.
2006: M Sifaki; M Assouti; Dragana Nikitovic; Konstantin Krasagakis; Nikos Karamanos; George N Tzanakakis
Lumican, a small leucine-rich proteoglycan substituted with keratan sulfate chains is expressed and secreted by human melanoma cells and not normal melanocytes.
IUBMB life 2006;58(10):606-10.
2006: Zaharenia Vlata; Filippos Porichis; George N Tzanakakis; Aristidis M Tsatsakis; Elias Krambovitis
A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells.
Toxicology letters 2006;165(3):274-81.
2006: George N Tzanakakis; Alexandra Syrokou; Ioannis Kanakis; Nikos Karamanos
Determination and distribution of N-acetyl- and N-glycolylneuraminic acids in culture media and cell-associated glycoconjugates from human malignant mesothelioma and adenocarcinoma cells.
Biomedical chromatography : BMC 2006;20(5):434-9.
2006: Olga Ch Kousidou; George N Tzanakakis; Nikos Karamanos
Effects of the natural isoflavonoid genistein on growth, signaling pathways and gene expression of matrix macromolecules by breast cancer cells.
Mini reviews in medicinal chemistry 2006;6(3):331-7.
2006: Ekatherina Charvalos; Manolis N Tzatzarakis; Françoise Van Bambeke; Paul Tulkens; Aristidis M Tsatsakis; George N Tzanakakis; Marie-Paule Mingeot-Leclercq
Water-soluble amphotericin B-polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects.
The Journal of antimicrobial chemotherapy 2006;57(2):236-44.
2006: Achilleas D Theocharis; Ioannis Tsolakis; George N Tzanakakis; Nikos Karamanos
Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression.
Advances in pharmacology (San Diego, Calif.) 2006;53():281-95.
2006: E Fthenou; Alexandros Zafiropoulos; Aristidis M Tsatsakis; A Stathopoulos; Nikos Karamanos; George N Tzanakakis
Chondroitin sulfate A chains enhance platelet derived growth factor-mediated signalling in fibrosarcoma cells.
The international journal of biochemistry & cell biology 2006;38(12):2141-50.
2006: Dragana Nikitovic; Alexandros Zafiropoulos; Pavlos Katonis; Aristidis M Tsatsakis; Achilleas D Theocharis; Nikos Karamanos; George N Tzanakakis
Transforming growth factor-beta as a key molecule triggering the expression of versican isoforms v0 and v1, hyaluronan synthase-2 and synthesis of hyaluronan in malignant osteosarcoma cells.
IUBMB life 2006;58(1):47-53.
2005: Zaharenia Vlata; Filippos Porichis; George N Tzanakakis; Aristidis M Tsatsakis; Elias Krambovitis
In vitro cytopathic effects of mycotoxin T-2 on human peripheral blood T lymphocytes.
Toxicology letters 2005;160(1):60-8.
2005: Nikolas C Papanikolaou; Eleftheria Hatzidaki; Stamatis Belivanis; George N Tzanakakis; Aristidis M Tsatsakis
Lead toxicity update. A brief review.
Medical science monitor : international medical journal of experimental and clinical research 2005;11(10):RA329-36.
2005: Dragana Nikitovic; Alexandros Zafiropoulos; George N Tzanakakis; Nikos Karamanos; Aristidis M Tsatsakis
Effects of glycosaminoglycans on cell proliferation of normal osteoblasts and human osteosarcoma cells depend on their type and fine chemical compositions.
Anticancer research 2005;25(4):2851-6.
2005: M A Savvopoulos; Eleftherios G Pallis; Manolis N Tzatzarakis; Ioanna A Dialyna; George N Tzanakakis; Aristidis M Tsatsakis
Legal issues of addiction assessment: the experience with hair testing in Greece.
Journal of applied toxicology : JAT 2005;25(2):143-52.
2004: George Bertsias; Pavlos Katonis; George N Tzanakakis; Aristidis M Tsatsakis
Review of clinical and toxicological features of acute pesticide poisonings in Crete (Greece) during the period 1991-2001.
Medical science monitor : international medical journal of experimental and clinical research 2004;10(11):CR622-7.
2004: Ioanna Dialyna; George N Tzanakakis; George Dolapsakis; Aristidis M Tsatsakis
A tetranucleotide repeat polymorphism in the CYP19 gene and breast cancer susceptibility in a Greek population exposed and not exposed to pesticides.
Toxicology letters 2004;151(1):267-71.
2004: Theoni N Mitropoulou; Achilleas D Theocharis; Dragana Nikitovic; Nikos Karamanos; George N Tzanakakis
IGF-I affects glycosaminoglycan/proteoglycan synthesis in breast cancer cells through tyrosine kinase-dependent and -independent pathways.
Biochimie 2004;86(4-5):251-9.
2003: Theoni N Mitropoulou; George N Tzanakakis; Dimitris Kletsas; Haralabos P Kalofonos; Nikos Karamanos
Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells.
International journal of cancer. Journal international du cancer 2003;104(2):155-60.
2003: George N Tzanakakis; Andrew N Margioris; Aristidis M Tsatsakis; Michael P Vezeridis
The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity.
International journal of gastrointestinal cancer 2003;34(1):27-38.
2003: Dragana Nikitovic; Aristidis M Tsatsakis; Nikos Karamanos; George N Tzanakakis
The effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by two osteosarcoma cell lines depends on tyrosine kinase and the estrogen receptor density.
Anticancer research 2003;23(1A):459-64.
2002: Alexandra Syrokou; Katalin Dobra; George N Tzanakakis; Anders Hjerpe; Nikos Karamanos
Synthesis and expression of mRNA encoding for different versican splice variants is related to the aggregation of human epithelial mesothelioma cells.
Anticancer research 2002;22(6C):4157-62.
2002: Theoni N Mitropoulou; George N Tzanakakis; Dragana Nikitovic; Aristidis M Tsatsakis; Nikos Karamanos
In vitro effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by estrogen receptor-positive and -negative human breast cancer epithelial cells.
Anticancer research 2002;22(5):2841-6.
2002: George N Tzanakakis; Elias Krambovitis; Aristidis M Tsatsakis; Michael P Vezeridis
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.
International journal of gastrointestinal cancer 2002;32(1):23-30.
2002: Stavroula Baritaki; George N Tzanakakis; John Alifragis; Alexandros Zafiropoulos; Ravshan I Tashmukhamedov; Aristidis M Tsatsakis; Mikhail I Shtilman; Apostolos Rizos; Elias Krambovitis
Light scattering and in vitro biocompatibility studies of poly (vinyl pyrrolidone) derivatives with amino-acid-dependent groups.
Journal of biomedical materials research 2002;63(6):830-7.
2002: Aristidis M Tsatsakis; George Bertsias; Vassiliki Liakou; I N Mammas; I Stiakakis; George N Tzanakakis
Severe fenthion intoxications due to ingestion and inhalation with survival outcome.
Human & experimental toxicology 2002;21(1):49-54.
1999: Alexandra Syrokou; George N Tzanakakis; Anders Hjerpe; Nikos Karamanos
Proteoglycans in human malignant mesothelioma. Stimulation of their synthesis induced by epidermal, insulin and platelet-derived growth factors involves receptors with tyrosine kinase activity.
Biochimie 1999;81(7):733-44.
1999: Alexandra Syrokou; George N Tzanakakis; Theodore Tsegenidis; Anders Hjerpe; Nikos Karamanos
Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: a structure-function relationship.
Cell proliferation 1999;32(2-3):85-99.
1997: George N Tzanakakis; Anders Hjerpe; Nikos Karamanos
Proteoglycan synthesis induced by transforming and basic fibroblast growth factors in human malignant mesothelioma is mediated through specific receptors and the tyrosine kinase intracellular pathway.
Biochimie 1997;79(6):323-32.
1997: Nikos Karamanos; P Vanky; George N Tzanakakis; Theodore Tsegenidis; Anders Hjerpe
Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparan sulphate.
Journal of chromatography. A 1997;765(2):169-79.
1996: George N Tzanakakis; Nikos Karamanos; Alexandra Syrokou; Anders Hjerpe
Effect of insulin and epidermal growth factors on the synthesis of glycosaminoglycans/proteoglycans in cultured human malignant mesothelioma cells of different phenotypic morphology.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1996;104(10):718-28.
1996: Nikos Karamanos; P Vanky; George N Tzanakakis; Anders Hjerpe
High performance capillary electrophoresis method to characterize heparin and heparan sulfate disaccharides.
Electrophoresis 1996;17(2):391-5.
1995: George N Tzanakakis; Nikos Karamanos; Anders Hjerpe
Effects on glycosaminoglycan synthesis in cultured human mesothelioma cells of transforming, epidermal, and fibroblast growth factors and their combinations with platelet-derived growth factor.
Experimental cell research 1995;220(1):130-7.
1995: Nikos Karamanos; S Axelsson; P Vanky; George N Tzanakakis; Anders Hjerpe
Determination of hyaluronan and galactosaminoglycan disaccharides by high-performance capillary electrophoresis at the attomole level. Applications to analyses of tissue and cell culture proteoglycans.
Journal of chromatography. A 1995;696(2):295-305.
1995: George N Tzanakakis; Nikos Karamanos; Julius Klominek; Anders Hjerpe
Glycosaminoglycans from two human malignant mesothelioma cell lines: determination, distribution, and effect of platelet-derived growth factor on their synthesis.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1995;73(1-2):59-66.
1993: George N Tzanakakis; K C Agarwal; Michael P Vezeridis
Prevention of human pancreatic cancer cell-induced hepatic metastasis in nude mice by dipyridamole and its analog RA-233.
Cancer 1993;71(8):2466-71.
1993: L M Tibbetts; C M Doremus; George N Tzanakakis; Michael P Vezeridis
Liver metastases with 10 human colon carcinoma cell lines in nude mice and association with carcinoembryonic antigen production.
Cancer 1993;71(2):315-21.
1992: K S McCully; George N Tzanakakis; Michael P Vezeridis
Effect of the synthetic N-homocysteine thiolactonyl derivatives, thioretinaco, thioretinamide, and thioco on growth and lactate production by malignant cells.
Research communications in chemical pathology and pharmacology 1992;77(1):125-8.
1992: Michael P Vezeridis; George N Tzanakakis; Patricia Meitner; C M Doremus; L M Tibbetts; P Calabresi
In vivo selection of a highly metastatic cell line from a human pancreatic carcinoma in the nude mouse.
Cancer 1992;69(8):2060-3.
1991: George N Tzanakakis; K C Agarwal; D K Veronikis; Michael P Vezeridis
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Journal of surgical oncology 1991;48(1):45-50.
1990: George N Tzanakakis; Michael P Vezeridis; Benjamin T Jackson; J V Rodil; K S McCully
Primary extranodal non-Hodgkin's lymphoma of the extrahepatic biliary tract.
Rhode Island medical journal 1990;73(10):483-6.
1990: R Bleday; George N Tzanakakis; M A Schwalke; H J Wanebo; Michael P Vezeridis
Epidermal growth factor stimulation and metastatic rate in human pancreatic carcinoma cell lines.
The Journal of surgical research 1990;49(3):276-9.
1990: M A Schwalke; George N Tzanakakis; Michael P Vezeridis
Effects of prostacyclin on hepatic metastases from human pancreatic cancer in the nude mouse.
The Journal of surgical research 1990;49(2):164-7.
1990: George N Tzanakakis; K S McCully; Michael P Vezeridis
Solitary cervical node metastasis in renal cell carcinoma.
Rhode Island medical journal 1990;73(3):113-5.
1990: George N Tzanakakis; K C Agarwal; Michael P Vezeridis
Inhibition of hepatic metastasis from a human pancreatic adenocarcinoma (RWP-2) in the nude mouse by prostacyclin, forskolin, and ketoconazole.
Cancer 1990;65(3):446-51.
1990: Michael P Vezeridis; Patricia Meitner; L M Tibbetts; C M Doremus; George N Tzanakakis; P Calabresi
Heterogeneity of potential for hematogenous metastasis in a human pancreatic carcinoma.
The Journal of surgical research 1990;48(1):51-5.
1989: George N Tzanakakis; K S McCully; Michael P Vezeridis
Benign papillary mesothelioma of the peritoneum: a consideration in the differential diagnosis of peritoneal implants.
Southern medical journal 1989;82(12):1579-80.
1989: K S McCully; George N Tzanakakis; Michael P Vezeridis
Inhibition of neoplastic growth by N-homocysteine thiolactonyl retinamido cobalamin.
Research communications in chemical pathology and pharmacology 1989;66(1):117-22.
1989: George N Tzanakakis; Chrisoula D Scopa; Michael P Vezeridis; Apostolos G Vagenakis
Ectopic bone in multinodular goiter.
Rhode Island medical journal 1989;72(5):171-2.
1989: Michael P Vezeridis; C M Doremus; L M Tibbetts; George N Tzanakakis; B T Jackson
Invasion and metastasis following orthotopic transplantation of human pancreatic cancer in the nude mouse.
Journal of surgical oncology 1989;40(4):261-5.
1989: George N Tzanakakis; D K Veronikis; E D Anastasiou; K S McCully; G Dimitracopoulos
Histopathological lesions produced by P. aeruginosa lipopolysaccharide in rats.
Journal of experimental pathology 1989;4(4):199-211.
1988: K Kotzamanoglou; George N Tzanakakis; E Michalopoulos; M Stathopoulou
Orbital cellulitis due to mucormycosis. A case report.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1988;226(6):539-41.