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Silvio Aime

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Sara Figueiredo; Carlos F G C Geraldes; João Nuno Moreira; Silvia Rizzitelli; Silvio Aime; Juan Carlos Cutrin; Elisa De Luca; Enzo Terreno
MRI tracking of macrophages labeled with glucan particles entrapping a water insoluble paramagnetic gd-based agent.
Giuseppe Ferrauto; Enzo Terreno; Daniela Delli Castelli; Silvio Aime
In vivo MRI visualization of different cell populations labeled with PARACEST agents.
Junyou Wang; Yun Yan; Aldrik H Velders; Frank J Vergeldt; Silvio Aime; Martien A Cohen Stuart; Arie de Keizer; Markus Drechsler; Eliana Gianolio; Henk Van As; Jasper van der Gucht
Controlled mixing of lanthanide(III) ions in coacervate core micelles.

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All Publications

2013: Sara Figueiredo; Carlos F G C Geraldes; João Nuno Moreira; Silvia Rizzitelli; Silvio Aime; Juan Carlos Cutrin; Elisa De Luca; Enzo Terreno
MRI tracking of macrophages labeled with glucan particles entrapping a water insoluble paramagnetic gd-based agent.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2013;15(3):307-15.
2013: Giuseppe Ferrauto; Enzo Terreno; Daniela Delli Castelli; Silvio Aime
In vivo MRI visualization of different cell populations labeled with PARACEST agents.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2013;69(6):1703-11.
2013: Junyou Wang; Yun Yan; Aldrik H Velders; Frank J Vergeldt; Silvio Aime; Martien A Cohen Stuart; Arie de Keizer; Markus Drechsler; Eliana Gianolio; Henk Van As; Jasper van der Gucht
Controlled mixing of lanthanide(III) ions in coacervate core micelles.
Chemical communications (Cambridge, England) 2013;49(36):3736-8.
2013: Juan Carlos Cutrin; Walter Dastrù; Diana Burghelea; Simonetta Geninatti Crich; Silvio Aime
Curcumin/Gd loaded apoferritin: a novel "theranostic" agent to prevent hepatocellular damage in toxic induced acute hepatitis.
Molecular pharmaceutics 2013;10(5):2079-85.
2013: Lucas W.E. Starmans; Sander M J van Duijnhoven; Silvio Aime; Mat J A P Daemen; Klaas Nicolay; Raffaella Rossin; Holger Grüll
SPECT imaging of fibrin using fibrin-binding peptides.
Contrast media & molecular imaging 2013;8(3):229-37.
2013: Valeria Catanzaro; Linda Chaabane; Walter Dastrù; Giuseppe Digilio; Concetta V Gringeri; Valeria Menchise; Sergio Padovan; Cinzia Boffa; Silvio Aime
A R2p /R1p ratiometric procedure to assess matrix metalloproteinase-2 activity by magnetic resonance imaging.
Angewandte Chemie (International ed. in English) 2013;52(14):3926-30.
2013: Roberta Napolitano; Giorgio Pariani; Silvio Aime; Markus Aswendt; Zsolt Baranyai; Franco Fedeli; Eliana Gianolio
Synthesis and relaxometric characterization of a MRI Gd-based probe responsive to glutamic acid decarboxylase enzymatic activity.
Journal of medicinal chemistry 2013;56(6):2466-77.
2013: Katherine M Payne; Edward J Valente; Silvio Aime; Mauro Botta; Mark Woods
Picture of a chelate in exchange: the crystal structure of NaHoDOTMA, a 'semi'-hydrated chelate.
Chemical communications (Cambridge, England) 2013;49(23):2320-2.
2013: Erika Cerutti; Annelaure Damont; Frédéric Dollé; Simona Baroni; Silvio Aime
Synthesis and characterization of an MRI Gd-based probe designed to target the translocator protein.
Magnetic resonance in chemistry : MRC 2013;51(2):116-22.
2013: Simonetta Geninatti Crich; Ibolya Szabo; Silvio Aime; Diego Alberti; Kristina Djanashvili
MRI visualization of melanoma cells by targeting overexpressed sialic acid with a Gd(III)-dota-en-pba imaging reporter.
Angewandte Chemie (International ed. in English) 2013;52(4):1161-4.
2013: Antonio Toppino; Paolo Venturello; Eliano Diana; Simonetta Geninatti Crich; Silvio Aime; Diego Alberti; Alessandro Barge; Maria Elena Bova; Annamaria Deagostino
A carborane-derivative "click" reaction under heterogeneous conditions for the synthesis of a promising lipophilic MRI/GdBNCT agent.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(2):721-8.
2012: Zsolt Baranyai; Alessandro Maiocchi; Zoltán Pálinkás; Fulvio Uggeri; Silvio Aime; Ernö Brücher
Dissociation kinetics of open-chain and macrocyclic gadolinium(III)-aminopolycarboxylate complexes related to magnetic resonance imaging: catalytic effect of endogenous ligands.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(51):16426-35.
2012: Veronica Fiorito; Simonetta Geninatti Crich; Lorenzo Silengo; Silvio Aime; Fiorella Altruda; noemi morello
Assessment of iron absorption in mice by ICP-MS measurements of (57)Fe levels.
European journal of nutrition 2012;51(7):783-9.
2012: Sonia Colombo Serra; Giovanni Battista Giovenzana; Magnus Karlsson; Fabio Tedoldi; Camilla Cavallotti; Silvio Aime
Hyperpolarized (13) C-labelled anhydrides as DNP precursors of metabolic MRI agents.
Contrast media & molecular imaging 2012;7(5):469-77.
2012: Markus Aswendt; Franco Fedeli; Eliana Gianolio; Uwe Himmelreich; Roberta Napolitano; Giorgio Pariani; Silvio Aime; Mathias Hoehn
In vivo imaging of inhibitory, GABAergic neurons by MRI.
NeuroImage 2012;62(3):1685-93.
2012: Mariapina D'Onofrio; David Fushman; Eliana Gianolio; Henriette Molinari; Serena Zanzoni; Silvio Aime; Francesca Arena; Alberto Ceccon; Michael Assfalg
High relaxivity supramolecular adducts between human-liver fatty-acid-binding protein and amphiphilic Gd(III) complexes: structural basis for the design of intracellular targeting MRI probes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(32):9919-28.
2012: Silvano Ellena; Roberto Gobetto; Alessandra Viale; Silvio Aime
Para-hydrogen induced polarization of Si-29 NMR resonances as a potentially useful tool for analytical applications.
Magnetic resonance in chemistry : MRC 2012;50(8):529-33.
2012: Federico A Rojas-Quijano; Gyula Tircsó; Enikő Tircsóné Benyó; Huan Tran Hoang; Silvio Aime; Zsolt Baranyai; Praveen K Gulaka; Ferenc K Kálmán; Vikram D Kodibagkar; Zoltán Kovács; A Dean Sherry
Synthesis and characterization of a hypoxia-sensitive MRI probe.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(31):9669-76.
2012: Enzo Terreno; Fulvio Uggeri; Silvio Aime
Image guided therapy: the advent of theranostic agents.
Journal of controlled release : official journal of the Controlled Release Society 2012;161(2):328-37.
2012: Francesca Reineri; Alessandra Viale; Diego Alberti; Tommaso Boi; Silvano Ellena; Giovanni Battista Giovenzana; Roberto Gobetto; Samuel S D Premkumar; Silvio Aime
15N magnetic resonance hyperpolarization via the reaction of parahydrogen with 15N-propargylcholine.
Journal of the American Chemical Society 2012;134(27):11146-52.
2012: Eliana Gianolio; Giovanni B Giovenzana; R Napolitano; S Porto; S Baroni; Silvio Aime
Relaxometric investigations and MRI evaluation of a liposome-loaded pH-responsive gadolinium(III) complex.
Inorganic chemistry 2012;51(13):7210-7.
2012: Alessandra Viale; Walter Dastrù; Francesca Reineri; Silvio Aime
Hyperpolarized (13)C-pyruvate magnetic resonance imaging in cancer diagnostics.
Expert opinion on medical diagnostics 2012;6(4):335-45.
2012: Maddalena Arigoni; Irmeli Barkefors; Giuseppina Barutello; Claudia Curcio; Lars Holmgren; Manuela Iezzi; Stefania Lanzardo; Dario Longo; Yujuan Zheng; Silvio Aime; Federica Cavallo
A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors.
Angiogenesis 2012;15(2):305-16.
2012: Simonetta Geninatti Crich; Antonio Toppino; Paolo Venturello; Diego Alberti; Annamaria Deagostino; Silvio Aime
Boronated compounds for imaging guided BNCT applications.
Anti-cancer agents in medicinal chemistry 2012;12(5):543-53.
2012: Pol Besenius; Paul H H Bomans; Joeri L M Heynens; Klaas Nicolay; Marko M L Nieuwenhuizen; Roel Straathof; Gustav J Strijkers; Enzo Terreno; Silvio Aime; EW Meijer
Paramagnetic self-assembled nanoparticles as supramolecular MRI contrast agents.
Contrast media & molecular imaging 2012;7(3):356-61.
2012: Simonetta Geninatti Crich; Achille Iolascon; Ferenc K Kálmán; Néstor R Lago; Stefania Lanzardo; Ibolya Szabó; Laura Conti; Juan Carlos Cutrin; Silvio Aime
Mn-loaded apoferritin: a highly sensitive MRI imaging probe for the detection and characterization of hepatocarcinoma lesions in a transgenic mouse model.
Contrast media & molecular imaging 2012;7(3):281-8.
2012: Evelina Cittadino; Bart J Crielaard; Marisa Ferraretto; Twan Lammers; Alessandro Maiocchi; Gert Storm; Silvio Aime; Elena Torres; Enzo Terreno
MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;45(4):436-41.
2012: Concetta V Gringeri; Valeria Menchise; Silvia Rizzitelli; Valeria Catanzaro; Linda Chaabane; Evelina Cittadino; Gabriele Dati; Giuseppe Digilio; Silvio Aime
Novel Gd(III)-based probes for MR molecular imaging of matrix metalloproteinases.
Contrast media & molecular imaging 2012;7(2):175-84.
2012: Ibolya Szabó; Diego Alberti; Simonetta Geninatti Crich; Ferenc K Kálmán; Silvio Aime
Mn loaded apoferritin as an MRI sensor of melanin formation in melanoma cells.
Chemical communications (Cambridge, England) 2012;48(18):2436-8.
2011: Simonetta Geninatti Crich; Dario Longo; Ibolya Szabo; Diego Alberti; Silvio Aime
MRI of cells and mice at 1 and 7 Tesla with Gd-targeting agents: when the low field is better!
Contrast media & molecular imaging 2011;6(6):421-5.
2011: Twan Lammers; Gert Storm; Silvio Aime; Wim E Hennink; Fabian Kiessling
Theranostic nanomedicine.
Accounts of chemical research 2011;44(10):1029-38.
2011: Sara Figueiredo; Carlos F G C Geraldes; João Nuno Moreira; Silvia Rizzitelli; Silvio Aime; Enzo Terreno
Yeast cell wall particles: a promising class of nature-inspired microcarriers for multimodal imaging.
Chemical communications (Cambridge, England) 2011;47(38):10635-7.
2011: Valeria Menchise; Carla Carrera; Valeria Catanzaro; Evelina Cittadino; Giuseppe Digilio; Eliana Gianolio; Silvio Aime
In vivo labeling of B16 melanoma tumor xenograft with a thiol-reactive gadolinium based MRI contrast agent.
Molecular pharmaceutics 2011;8(5):1750-6.
2011: Silvio Aime; Mauro Botta; Zoltán Garda; Benjamin E Kucera; Gyula Tircso; Victor G Young; Mark Woods
Properties, solution state behavior, and crystal structures of chelates of DOTMA.
Inorganic chemistry 2011;50(17):7955-65.
2011: Elena Torres; Silvio Aime; Roberta Cavalli; Franco Fedeli; Francesco Mainini; Roberta Napolitano; Enzo Terreno
Improved paramagnetic liposomes for MRI visualization of pH triggered release.
Journal of controlled release : official journal of the Controlled Release Society 2011;154(2):196-202.
2011: Francesca Reineri; Alessandra Viale; Tommaso Boi; Valeria Daniele; Silvano Ellena; Roberto Gobetto; Silvio Aime
Use of labile precursors for the generation of hyperpolarized molecules from hydrogenation with parahydrogen and aqueous-phase extraction.
Angewandte Chemie (International ed. in English) 2011;50(32):7350-3.
2011: Simonetta Geninatti Crich; Nicoletta Protti; Sabrina Stella; Ibolya Szabo; Antonio Toppino; Paolo Venturello; Diego Alberti; Saverio Altieri; Francesca Ballarini; Alessandro Barge; Silva Bortolussi; Piero Bruschi; Annamaria Deagostino; Silvio Aime
MRI-guided neutron capture therapy by use of a dual gadolinium/boron agent targeted at tumour cells through upregulated low-density lipoprotein transporters.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(30):8479-86.
2011: Enzo Terreno; Cinzia Boffa; Valeria Menchise; Franco Fedeli; Carla Carrera; Daniela Delli Castelli; Giuseppe Digilio; Silvio Aime
Gadolinium-doped LipoCEST agents: a potential novel class of dual 1H-MRI probes.
Chemical communications (Cambridge, England) 2011;47(16):4667-9.
2011: Silvio Aime; Francesca Reineri
Advances in bio-imaging: a survey from WWMR 2010.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2011;209(2):109-15.
2011: Francesca Reineri; Alessandra Viale; Walter Dastrù; Roberto Gobetto; Silvio Aime
How to design 13C para-hydrogen-induced polarization experiments for MRI applications.
Contrast media & molecular imaging 2011;6(2):77-84.
2011: Ya-Hui Chang; Chiao-Yun Chen; Gyan Singh; Hsing-Yin Chen; Guocheng liu; Yih-Gang Goan; Silvio Aime; Yun-Ming Wang
Synthesis and physicochemical characterization of carbon backbone modified [Gd(TTDA)(H2O)]2- derivatives.
Inorganic chemistry 2011;50(4):1275-87.
2011: Daniela Delli Castelli; Enzo Terreno; Silvio Aime
Yb(III)-HPDO3A: a dual pH- and temperature-responsive CEST agent.
Angewandte Chemie (International ed. in English) 2011;50(8):1798-800.
2011: Eliana Gianolio; Luca Maciocco; Daniela Imperio; Giovanni B Giovenzana; Federica Simonelli; Kamel Abbas; Gianni Bisi; Silvio Aime
Dual MRI-SPECT agent for pH-mapping.
Chemical communications (Cambridge, England) 2011;47(5):1539-41.
2011: Carsten Schultz; Silvio Aime
Imaging probes--Introduction.
Bioorganic & medicinal chemistry 2011;19(3):1022.
2011: Sara Figueiredo; João Nuno Moreira; Carlos F G C Geraldes; Silvio Aime; Enzo Terreno
Supramolecular protamine/Gd-loaded liposomes adducts as relaxometric protease responsive probes.
Bioorganic & medicinal chemistry 2011;19(3):1131-5.
2011: Dara O Hógáin; Gareth R Davies; Simona Baroni; Silvio Aime; David J Lurie
The use of contrast agents with fast field-cycling magnetic resonance imaging.
Physics in medicine and biology 2011;56(1):105-15.
2011: Eliana Gianolio; Francesca Arena; Gustav J Strijkers; Klaas Nicolay; Anders Högset; Silvio Aime
Photochemical activation of endosomal escape of MRI-Gd-agents in tumor cells.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2011;65(1):212-9.
2011: Dario Livio Longo; Walter Dastrù; Giuseppe Digilio; Jochen Keupp; Sander Langereis; Stefania Lanzardo; Simone Prestigio; Oliver Steinbach; Enzo Terreno; Fulvio Uggeri; Silvio Aime
Iopamidol as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys: In vivo studies in mice at 7 T.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2011;65(1):202-11.
2010: Lorenzo Tei; Alessandro Barge; Simonetta Geninatti Crich; Roberto Pagliarin; Viviana Negri; Daniela Ramella; Giancarlo Cravotto; Silvio Aime
Target visualization by MRI using the avidin/biotin amplification route: synthesis and testing of a biotin-Gd-DOTA monoamide trimer.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(27):8080-7.
2010: Giuseppe Digilio; Valeria Menchise; Eliana Gianolio; Valeria Catanzaro; Carla Carrera; Roberta Napolitano; Franco Fedeli; Silvio Aime
Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling.
Journal of medicinal chemistry 2010;53(13):4877-90.
2010: Lorenzo Tei; Galit Mazooz; Yael Shellef; Reut Avni; Katrien Vandoorne; Alessandro Barge; Vyacheslav Kalchenko; Mark W Dewhirst; Linda Chaabane; Luigi Miragoli; Dario Longo; Michal Neeman; Silvio Aime
Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity.
Contrast media & molecular imaging 2010;5(4):213-22.
2010: Daniela Delli Castelli; Walter Dastrù; Enzo Terreno; Evelina Cittadino; Francesco Mainini; Elena Torres; Michela Spadaro; Silvio Aime
In vivo MRI multicontrast kinetic analysis of the uptake and intracellular trafficking of paramagnetically labeled liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2010;144(3):271-9.
2010: Francesca Reineri; Daniela Santelia; Alessandra Viale; Erika Cerutti; Luisa Poggi; Tomas Tichy; Samuel S D Premkumar; Roberto Gobetto; Silvio Aime
Para-hydrogenated glucose derivatives as potential 13C-hyperpolarized probes for magnetic resonance imaging.
Journal of the American Chemical Society 2010;132(20):7186-93.
2010: Enzo Terreno; Daniela Delli Castelli; Alessandra Viale; Silvio Aime
Challenges for molecular magnetic resonance imaging.
Chemical reviews 2010;110(5):3019-42.
2010: Cristina Grange; Simonetta Geninatti Crich; Giovanna Esposito; Diego Alberti; Lorenzo Tei; Benedetta Bussolati; Silvio Aime; Giovanni Camussi
Combined delivery and magnetic resonance imaging of neural cell adhesion molecule-targeted doxorubicin-containing liposomes in experimentally induced Kaposi's sarcoma.
Cancer research 2010;70(6):2180-90.
2010: Enzo Terreno; Daniela Delli Castelli; Silvio Aime
Encoding the frequency dependence in MRI contrast media: the emerging class of CEST agents.
Contrast media & molecular imaging 2010;5(2):78-98.
2010: Alessandra Viale; Silvio Aime
Current concepts on hyperpolarized molecules in MRI.
Current opinion in chemical biology 2010;14(1):90-6.
2010: Emily L Que; Eliana Gianolio; Suzanne L Baker; Silvio Aime; Christopher J Chang
A copper-activated magnetic resonance imaging contrast agent with improved turn-on relaxivity response and anion compatibility.
Dalton transactions (Cambridge, England : 2003) 2010;(2):469-76.
2010: Enzo Terreno; Walter Dastrù; D Delli Castelli; Eliana Gianolio; S Geninatti Crich; Dario Longo; Silvio Aime
Advances in metal-based probes for MR molecular imaging applications.
Current medicinal chemistry 2010;17(31):3684-700.
2010: Ferenc Krisztián Kálmán; Simonetta Geninatti Crich; Silvio Aime
Reduction/dissolution of a beta-MnOOH nanophase in the ferritin cavity to yield a highly sensitive, biologically compatible magnetic resonance imaging agent.
Angewandte Chemie (International ed. in English) 2010;49(3):612-5.
2009: Federico A Rojas-Quijano; Eniko Tircsóné Benyó; Gyula Tircsó; Ferenc K Kálmán; Zsolt Baranyai; Silvio Aime; A Dean Sherry; Zoltán Kovács
Lanthanide(III) complexes of tris(amide) PCTA derivatives as potential bimodal magnetic resonance and optical imaging agents.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(47):13188-200.
2009: Silvio Aime; Peter Caravan
Biodistribution of gadolinium-based contrast agents, including gadolinium deposition.
Journal of magnetic resonance imaging : JMRI 2009;30(6):1259-67.
2009: Daniela Delli Castelli; Enzo Terreno; Claudia Cabella; Linda Chaabane; Stefania Lanzardo; Lorenzo Tei; Massimo Visigalli; Silvio Aime
Evidence for in vivo macrophage mediated tumor uptake of paramagnetic/fluorescent liposomes.
NMR in biomedicine 2009;22(10):1084-92.
2009: Eliana Gianolio; Roberta Napolitano; Franco Fedeli; Francesca Arena; Silvio Aime
Poly-beta-cyclodextrin based platform for pH mapping via a ratiometric 19F/1H MRI method.
Chemical communications (Cambridge, England) 2009;(40):6044-6.
2009: Eric J Werner; Mauro Botta; Silvio Aime; Kenneth N Raymond
Effect of a mesitylene-based ligand cap on the relaxometric properties of Gd(III) hydroxypyridonate MRI contrast agents.
Contrast media & molecular imaging 2009;4(5):220-9.
2009: Enzo Terreno; Joseph Stancanello; Dario Longo; Daniela Delli Castelli; Luciano Milone; Honorius M H F Sanders; Maarten B Kok; Fulvio Uggeri; Silvio Aime
Methods for an improved detection of the MRI-CEST effect.
Contrast media & molecular imaging 2009;4(5):237-47.
2009: Francesca Reineri; Daniela Santelia; Roberto Gobetto; Silvio Aime
Effect of low and zero magnetic field on the hyperpolarization lifetime in parahydrogenated perdeuterated molecules.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2009;200(1):15-20.
2009: Patrizia Siega; Jochen Wuerges; Francesca Arena; Eliana Gianolio; Sergey N Fedosov; Renata Dreos; Silvano Geremia; Silvio Aime; Lucio Randaccio
Release of toxic Gd3+ ions to tumour cells by vitamin B12 bioconjugates.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(32):7980-9.
2009: Antonella Crivello; Carlo Nervi; Roberto Gobetto; Simonetta Geninatti Crich; Iboya Szabo; Alessandro Barge; Antonio Toppino; Annamaria Deagostino; Paolo Venturello; Silvio Aime
Towards improved boron neutron capture therapy agents: evaluation of in vitro cellular uptake of a glutamine-functionalized carborane.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2009;14(6):883-90.
2009: Simona Baroni; Giorgio Pariani; Gabriella Fanali; Dario Longo; Paolo Ascenzi; Silvio Aime; Mauro Fasano
Thermodynamic analysis of hydration in human serum heme-albumin.
Biochemical and biophysical research communications 2009;385(3):385-9.
2009: Silvio Aime; Daniela Delli Castelli; Simonetta Geninatti Crich; Eliana Gianolio; Enzo Terreno
Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications.
Accounts of chemical research 2009;42(7):822-31.
2009: Thomas J Meade; Silvio Aime
Chemistry of molecular imaging.
Accounts of chemical research 2009;42(7):821.
2009: Emily L Que; Eliana Gianolio; Suzanne L Baker; Audrey P Wong; Silvio Aime; Christopher J Chang
Copper-responsive magnetic resonance imaging contrast agents.
Journal of the American Chemical Society 2009;131(24):8527-36.
2009: Karen C Briley-Saebo; Simonetta Geninatti Crich; David P Cormode; Alessandra Barazza; Willem J M Mulder; Wei Chen; Giovanni B Giovenzana; Edward A Fisher; Silvio Aime; Zahi A Fayad
High-relaxivity gadolinium-modified high-density lipoproteins as magnetic resonance imaging contrast agents.
The journal of physical chemistry. B 2009;113(18):6283-9.
2009: Simona Baroni; Roberto Consonni; Gianni Ferrante; Silvio Aime
Relaxometric studies for food characterization: the case of balsamic and traditional balsamic vinegars.
Journal of agricultural and food chemistry 2009;57(8):3028-32.
2009: Aldo Cagnolini; Nicola D'Amelio; Edmund Metcalfe; Hanh D Nguyen; Silvio Aime; Rolf E Swenson; Karen Linder
Isolation of a 177Hf complex formed by beta-decay of a 177Lu-labeled radiotherapeutic compound and NMR structural elucidation of the ligand and its Lu and Hf complexes.
Inorganic chemistry 2009;48(7):3114-24.
2009: Elisa M Elemento; David Parker; Silvio Aime; Eliana Gianolio; Luciano Lattuada
Variation of water exchange dynamics with ligand structure and stereochemistry in lanthanide complexes based on 1,4-diazepine derivatives.
Organic & biomolecular chemistry 2009;7(6):1120-31.
2009: Giuseppe Digilio; Valeria Catanzaro; Franco Fedeli; Eliana Gianolio; Valeria Menchise; Roberta Napolitano; Concetta Gringeri; Silvio Aime
Targeting exofacial protein thiols with Gd(III) complexes. An efficient procedure for MRI cell labelling.
Chemical communications (Cambridge, England) 2009;(8):893-5.
2009: Silvio Aime; Eliana Gianolio; Francesca Arena; Alessandro Barge; Katia Martina; George Heropoulos; Giancarlo Cravotto
New cyclodextrin dimers and trimers capable of forming supramolecular adducts with shape-specific ligands.
Organic & biomolecular chemistry 2009;7(2):370-9.
2009: Esad Vucic; Honorius M H F Sanders; Francesca Arena; Enzo Terreno; Silvio Aime; Klaas Nicolay; Eik Leupold; Margitta Dathe; Nico Sommerdijk; Zahi A Fayad; Willem J M Mulder
Well-defined, multifunctional nanostructures of a paramagnetic lipid and a lipopeptide for macrophage imaging.
Journal of the American Chemical Society 2009;131(2):406-7.
2009: Eric J Werner; Julia Kozhukh; Mauro Botta; Evan G Moore; Stefano Avedano; Silvio Aime; Kenneth N Raymond
1,2-hydroxypyridonate/terephthalamide complexes of gadolinium(III): synthesis, stability, relaxivity, and water exchange properties.
Inorganic chemistry 2009;48(1):277-86.
2009: Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Chapter 10 - Lanthanide-loaded paramagnetic liposomes as switchable magnetically oriented nanovesicles.
Methods in enzymology 2009;464():193-210.
2009: Zsolt Baranyai; Fulvio Uggeri; Giovanni B Giovenzana; Attila Bényei; Erno Brücher; Silvio Aime
Equilibrium and kinetic properties of the lanthanoids(III) and various divalent metal complexes of the heptadentate ligand AAZTA.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(7):1696-705.
2009: Enzo Terreno; Daniela Delli Castelli; Elisabetta Violante; Honorius M H F Sanders; Nico Sommerdijk; Silvio Aime
Osmotically shrunken LIPOCEST agents: an innovative class of magnetic resonance imaging contrast media based on chemical exchange saturation transfer.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(6):1440-8.
2009: Rachele Stefania; Lorenzo Tei; Alessandro Barge; Simonetta Geninatti Crich; Ibolya Szabo; Claudia Cabella; Giancarlo Cravotto; Silvio Aime
Tuning glutamine binding modes in Gd-DOTA-based probes for an improved MRI visualization of tumor cells.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(1):76-85.
2008: Aldo Arrais; Mauro Botta; Stefano Avedano; Giovanni Battista Giovenzana; Eliana Gianolio; Enrico Boccaleri; Pier Luigi Stanghellini; Silvio Aime
Carbon coated microshells containing nanosized Gd(III) oxidic phases for multiple bio-medical applications.
Chemical communications (Cambridge, England) 2008;(45):5936-8.
2008: Silvio Aime; Alessandro Barge; Antonella Crivello; Annamaria Deagostino; Roberto Gobetto; Carlo Nervi; Cristina Prandi; Antonio Toppino; Paolo Venturello
Synthesis of Gd(III)-C-palmitamidomethyl-C'-DOTAMA-C(6)-o-carborane: a new dual agent for innovative MRI/BNCT applications.
Organic & biomolecular chemistry 2008;6(23):4460-6.
2008: Simona Tomaselli; Serena Zanzoni; Laura Ragona; Eliana Gianolio; Silvio Aime; Michael Assfalg; Henriette Molinari
Solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based gadolinium(III)-chelate, a potential hepatospecific magnetic resonance imaging contrast agent.
Journal of medicinal chemistry 2008;51(21):6782-92.
2008: Francesca Reineri; Alessandra Viale; Giovanbattista Giovenzana; Daniela Santelia; Walter Dastrù; Roberto Gobetto; Silvio Aime
New hyperpolarized contrast agents for 13C-MRI from para-hydrogenation of oligooxyethylenic alkynes.
Journal of the American Chemical Society 2008;130(45):15047-53.
2008: Enzo Terreno; Daniela Delli Castelli; Claudia Cabella; Walter Dastrù; Alberto Sanino; Joseph Stancanello; Lorenzo Tei; Silvio Aime
Paramagnetic liposomes as innovative contrast agents for magnetic resonance (MR) molecular imaging applications.
Chemistry & biodiversity 2008;5(10):1901-12.
2008: Lorenzo Tei; Zsolt Baranyai; Mauro Botta; Laura Piscopo; Silvio Aime; Giovanni B Giovenzana
Synthesis and solution thermodynamic study of rigidified and functionalised EGTA derivatives.
Organic & biomolecular chemistry 2008;6(13):2361-8.
2008: Ferenc K Kálmán; Zsolt Baranyai; Imre Tóth; István Bányai; Róbert Király; Ernö Brücher; Silvio Aime; Xiankai Sun; A Dean Sherry; Zoltán Kovács
Synthesis, potentiometric, kinetic, and NMR Studies of 1,4,7,10-tetraazacyclododecane-1,7-bis(acetic acid)-4,10-bis(methylenephosphonic acid) (DO2A2P) and its complexes with Ca(II), Cu(II), Zn(II) and lanthanide(III) ions.
Inorganic chemistry 2008;47(9):3851-62.
2008: Caterina Canavese; M Cristina Mereu; Silvio Aime; Elisa Lazzarich; Roberta Fenoglio; Marco Quaglia; Piero Stratta
Gadolinium-associated nephrogenic systemic fibrosis: the need for nephrologists' awareness.
Journal of nephrology 2008;21(3):324-36.
2008: Enzo Terreno; Alberto Sanino; Carla Carrera; Daniela Delli Castelli; Giovanni B Giovenzana; Alberto Lombardi; Roberta Mazzon; Luciano Milone; Massimo Visigalli; Silvio Aime
Determination of water permeability of paramagnetic liposomes of interest in MRI field.
Journal of inorganic biochemistry 2008;102(5-6):1112-9.
2008: Simona Ghiani; Simona Baroni; Daniela Burgio; Giuseppe Digilio; Masaki Fukuhara; Paola Martino; Keiji Monda; Carlo Nervi; Akira Kiyomine; Silvio Aime
Characterization of human hair melanin and its degradation products by means of magnetic resonance techniques.
Magnetic resonance in chemistry : MRC 2008;46(5):471-9.
2008: Daniela Delli Castelli; Enzo Terreno; Carla Carrera; Giovanni B Giovenzana; Roberta Mazzon; Simona Rollet; Massimo Visigalli; Silvio Aime
Lanthanide-loaded paramagnetic liposomes as switchable magnetically oriented nanovesicles.
Inorganic chemistry 2008;47(8):2928-30.
2008: Alessandro Barge; Lorenzo Tei; Dharita Upadhyaya; Franco Fedeli; Lorena Beltrami; Rachele Stefanìa; Silvio Aime; Giancarlo Cravotto
Bifunctional ligands based on the DOTA-monoamide cage.
Organic & biomolecular chemistry 2008;6(7):1176-84.
2008: Simona Ramponi; Cristina Rebaudengo; Claudia Cabella; Adriana Grotti; Stefania Vultaggio; Silvio Aime; Alberto Morisetti; Vito Lorusso
Contrast-enhanced MRI of murine sponge model for progressive angiogenesis assessed with gadoteridol (ProHance) and gadocoletic acid trisodium salt (B22956/1).
Journal of magnetic resonance imaging : JMRI 2008;27(4):872-80.
2008: Ankona Datta; Jacob M Hooker; Mauro Botta; Matt B Francis; Silvio Aime; Kenneth N Raymond
High relaxivity gadolinium hydroxypyridonate-viral capsid conjugates: nanosized MRI contrast agents.
Journal of the American Chemical Society 2008;130(8):2546-52.
2008: Enzo Terreno; Alessandro Barge; Lorena Beltrami; Giancarlo Cravotto; Daniela Delli Castelli; Franco Fedeli; Bhagavathsingh Jebasingh; Silvio Aime
Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents.
Chemical communications (Cambridge, England) 2008;(5):600-2.
2008: Lorenzo Tei; Mauro Botta; Clara Lovazzano; Alessandro Barge; Luciano Milone; Silvio Aime
1H and 17O NMR relaxometric study in aqueous solution of Gd(III) complexes of EGTA-like derivatives bearing methylenephosphonic groups.
Magnetic resonance in chemistry : MRC 2008;46 Suppl 1():S86-93.
2008: Silvio Aime; Walter Dastrù; Roberto Gobetto; Daniela Santelia; Alessandra Viale
Agents for polarization enhancement in MRI.
Handbook of experimental pharmacology 2008;(185 Pt 1):247-72.
2008: Elisa Battistini; Eliana Gianolio; Ruxandra Gref; Patrick Couvreur; Silvia Fuzerova; Mohammad Othman; Silvio Aime; Bernard Badet; Philippe Durand
High-relaxivity magnetic resonance imaging (MRI) contrast agent based on supramolecular assembly between a gadolinium chelate, a modified dextran, and poly-beta-cyclodextrin.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(15):4551-61.
2008: Enzo Terreno; Daniela Delli Castelli; Luciano Milone; Simona Rollet; Joseph Stancanello; Elisabetta Violante; Silvio Aime
First ex-vivo MRI co-localization of two LIPOCEST agents.
Contrast media & molecular imaging 2008;3(1):38-43.
2008: Eliana Gianolio; Giovanni Battista Giovenzana; Anna Ciampa; Stefania Lanzardo; Daniela Imperio; Silvio Aime
A novel method of cellular labeling: anchoring mr-imaging reporter particles on the outer cell surface.
ChemMedChem 2008;3(1):60-2.
2007: Stefano Avedano; Lorenzo Tei; Alberto Lombardi; Giovanni B Giovenzana; Silvio Aime; Dario Longo; Mauro Botta
Maximizing the relaxivity of HSA-bound gadolinium complexes by simultaneous optimization of rotation and water exchange.
Chemical communications (Cambridge, England) 2007;(45):4726-8.
2007: Simonetta Geninatti Crich; Stefania Lanzardo; Diego Alberti; Simona Belfiore; Anna Ciampa; Giovanni B Giovenzana; Clara Lovazzano; Roberto Pagliarin; Silvio Aime
Magnetic resonance imaging detection of tumor cells by targeting low-density lipoprotein receptors with Gd-loaded low-density lipoprotein particles.
Neoplasia (New York, N.Y.) 2007;9(12):1046-56.
2007: Carla Carrera; Giuseppe Digilio; Simona Baroni; Daniela Burgio; Simona Consol; Franco Fedeli; Dario Longo; Armando Mortillaro; Silvio Aime
Synthesis and characterization of a Gd(III) based contrast agent responsive to thiol containing compounds.
Dalton transactions (Cambridge, England : 2003) 2007;(43):4980-7.
2007: Michael Assfalg; Eliana Gianolio; Serena Zanzoni; Simona Tomaselli; Vito Lo Russo; Claudia Cabella; Laura Ragona; Silvio Aime; Henriette Molinari
NMR structural studies of the supramolecular adducts between a liver cytosolic bile acid binding protein and gadolinium(III)-chelates bearing bile acids residues: molecular determinants of the binding of a hepatospecific magnetic resonance imaging contrast agent.
Journal of medicinal chemistry 2007;50(22):5257-68.
2007: Christoph J Jocher; Evan G Moore; Jide Xu; Stefano Avedano; Mauro Botta; Silvio Aime; Kenneth N Raymond
1,2-hydroxypyridonates as contrast agents for magnetic resonance imaging: TREN-1,2-HOPO.
Inorganic chemistry 2007;46(22):9182-91.
2007: Benedetta Bussolati; Cristina Grange; Lorenzo Tei; Maria Chiara Deregibus; Mauro Ercolani; Silvio Aime; Giovanni Camussi
Targeting of human renal tumor-derived endothelial cells with peptides obtained by phage display.
Journal of molecular medicine (Berlin, Germany) 2007;85(8):897-906.
2007: Elisa Battistini; Armando Mortillaro; Silvio Aime; Joop A Peters
Molecular recognition of sugars by lanthanide (III) complexes of a conjugate of N, N-bis[2-[bis[2-(1, 1-dimethylethoxy)-2-oxoethyl]amino]ethyl]glycine and phenylboronic acid.
Contrast media & molecular imaging 2007;2(4):163-71.
2007: Christoph J Jocher; Mauro Botta; Stefano Avedano; Evan G Moore; Jide Xu; Silvio Aime; Kenneth N Raymond
Optimized relaxivity and stability of [Gd(H(2,2)-1,2-HOPO)(H2O)]- for use as an MRI contrast agent.
Inorganic chemistry 2007;46(12):4796-8.
2007: Diego Tesauro; Antonella Accardo; Eliana Gianolio; Luigi Paduano; José Teixeira; Karin Schillén; Silvio Aime; Giancarlo Morelli
Peptide derivatized lamellar aggregates as target-specific MRI contrast agents.
Chembiochem : a European journal of chemical biology 2007;8(8):950-5.
2007: Silvio Aime; Daniela Delli Castelli; Dale Lawson; Enzo Terreno
Gd-loaded liposomes as T1, susceptibility, and CEST agents, all in one.
Journal of the American Chemical Society 2007;129(9):2430-1.
2007: Zsolt Baranyai; Eliana Gianolio; Kondareddiar Ramalingam; Rolf Swenson; Ramachandran Ranganathan; Ernö Brücher; Silvio Aime
The effects of intramolecular H-bond formation on the stability constant and water exchange rate of the Gd(III)-diethylenetriamine-N'-(3-amino-1,1-propylenephosphonic)-N, N,N'',N''-tetraacetate complex.
Contrast media & molecular imaging 2007;2(2):94-102.
2007: Eric J Werner; Stefano Avedano; Mauro Botta; Benjamin P Hay; Evan G Moore; Silvio Aime; Kenneth N Raymond
Highly soluble tris-hydroxypyridonate Gd(III) complexes with increased hydration number, fast water exchange, slow electronic relaxation, and high relaxivity.
Journal of the American Chemical Society 2007;129(7):1870-1.
2007: Elisenda Rodríguez; Rui V Simoes; Anna Roig; Elies Molins; Nataliya Nedelko; Anna Slawska-Waniewska; Silvio Aime; Carles Arús; Miquel E Cabañas; Coral Sanfeliu; Sebastián Cerdán; Maria Luisa García-Martín
An iron-based T1 contrast agent made of iron-phosphate complexes: in vitro and in vivo studies.
Magma (New York, N.Y.) 2007;20(1):27-37.
2007: Antonella Accardo; Diego Tesauro; Giancarlo Morelli; Eliana Gianolio; Silvio Aime; Mauro Vaccaro; Gaetano Mangiapia; Luigi Paduano; Karin Schillén
High-relaxivity supramolecular aggregates containing peptides and Gd complexes as contrast agents in MRI.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2007;12(2):267-76.
2007: Livia Biancone; Simonetta Geninatti Crich; Vincenzo Cantaluppi; Giuseppe Mauriello Romanazzi; Simona Russo; Elisa Scalabrino; Giovanna Esposito; Federico Figliolini; Silvia Beltramo; Paolo Cavallo Perin; Giuseppe Paolo Segoloni; Silvio Aime; Giovanni Camussi
Magnetic resonance imaging of gadolinium-labeled pancreatic islets for experimental transplantation.
NMR in biomedicine 2007;20(1):40-8.
2007: Eliana Gianolio; Giovanni B Giovenzana; Dario Longo; Irene Longo; Ivan Menegotto; Silvio Aime
Relaxometric and modelling studies of the binding of a lipophilic Gd-AAZTA complex to fatted and defatted human serum albumin.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(20):5785-97.
2007: Enzo Terreno; Claudia Cabella; Carla Carrera; Daniela Delli Castelli; Roberta Mazzon; Simona Rollet; Joseph Stancanello; Massimo Visigalli; Silvio Aime
From spherical to osmotically shrunken paramagnetic liposomes: an improved generation of LIPOCEST MRI agents with highly shifted water protons.
Angewandte Chemie (International ed. in English) 2007;46(6):966-8.
2006: Amber L Thompson; David Parker; David A Fulton; Judith A K Howard; Shashi U Pandya; Horst Puschmann; Kanthi Senanayake; Philip A Stenson; Alessandra Badari; Mauro Botta; Stefano Avedano; Silvio Aime
On the role of the counter-ion in defining water structure and dynamics: order, structure and dynamics in hydrophilic and hydrophobic gadolinium salt complexes.
Dalton transactions (Cambridge, England : 2003) 2006;(47):5605-16.
2006: Erik Bruno; Giuseppe Digilio; Claudia Cabella; Andrea de Reggi; Simona Baroni; Valentina Mainero; Silvio Aime
Water exchange across the erythrocyte plasma membrane studied by HR-MAS NMR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(5):978-85.
2006: Valérie C Pierre; Mauro Botta; Silvio Aime; Kenneth N Raymond
Substituent effects on Gd(III)-based MRI contrast agents: optimizing the stability and selectivity of the complex and the number of coordinated water molecules.
Inorganic chemistry 2006;45(20):8355-64.
2006: Sabrina Benedetto; Roberta Pulito; Simonetta Geninatti Crich; Guido Tarone; Silvio Aime; Lorenzo Silengo; Jörg Hamm
Quantification of the expression level of integrin receptor alpha(v)beta3 in cell lines and MR imaging with antibody-coated iron oxide particles.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(4):711-6.
2006: Simonetta Geninatti Crich; Benedetta Bussolati; Lorenzo Tei; Cristina Grange; Giovanna Esposito; Stefania Lanzardo; Giovanni Camussi; Silvio Aime
Magnetic resonance visualization of tumor angiogenesis by targeting neural cell adhesion molecules with the highly sensitive gadolinium-loaded apoferritin probe.
Cancer research 2006;66(18):9196-201.
2006: Silvio Aime; Franco Fedeli; Alberto Sanino; Enzo Terreno
A R2/R1 ratiometric procedure for a concentration-independent, pH-responsive, Gd(III)-based MRI agent.
Journal of the American Chemical Society 2006;128(35):11326-7.
2006: Simonetta Geninatti Crich; Claudia Cabella; Alessandro Barge; Simona Belfiore; Cristina Ghirelli; Luciano Lattuada; Stefania Lanzardo; Armando Mortillaro; Lorenzo Tei; Massimo Visigalli; Guido Forni; Silvio Aime
In vitro and in vivo magnetic resonance detection of tumor cells by targeting glutamine transporters with Gd-based probes.
Journal of medicinal chemistry 2006;49(16):4926-36.
2006: Luciano Lattuada; Silvia Demattio; Veronica Vincenzi; Claudia Cabella; Massimo Visigalli; Silvio Aime; Simonetta Geninatti Crich; Eliana Gianolio
Magnetic resonance imaging of tumor cells by targeting the amino acid transport system.
Bioorganic & medicinal chemistry letters 2006;16(15):4111-4.
2006: Valérie C Pierre; Mauro Botta; Silvio Aime; Kenneth N Raymond
Fe(III)-templated Gd(III) self-assemblies-a new route toward macromolecular MRI contrast agents.
Journal of the American Chemical Society 2006;128(29):9272-3.
2006: Jakub Rudovský; Mauro Botta; Petr Hermann; Kenneth I Hardcastle; Ivan Lukes; Silvio Aime
PAMAM dendrimeric conjugates with a Gd-DOTA phosphinate derivative and their adducts with polyaminoacids: the interplay of global motion, internal rotation, and fast water exchange.
Bioconjugate chemistry 2006;17(4):975-87.
2006: Jakub Rudovský; Mauro Botta; Petr Hermann; Avtandil Koridze; Silvio Aime
Relaxometric and solution NMR structural studies on ditopic lanthanide(III) complexes of a phosphinate analogue of DOTA with a fast rate of water exchange.
Dalton transactions (Cambridge, England : 2003) 2006;(19):2323-33.
2006: Enzo Terreno; Mauro Botta; Walter Dastrù; Silvio Aime
Gd-enhanced MR images of substrates other than water.
Contrast media & molecular imaging 2006;1(3):101-5.
2006: Silvio Aime; Eliana Gianolio; Fulvio Uggeri; Silvia Tagliapietra; Alessandro Barge; Giancarlo Cravotto
New paramagnetic supramolecular adducts for MRI applications based on non-covalent interactions between Gd(III)-complexes and beta- or gamma-cyclodextrin units anchored to chitosan.
Journal of inorganic biochemistry 2006;100(5-6):931-8.
2006: Valérie C Pierre; Mauro Botta; Silvio Aime; Kenneth N Raymond
Tuning the coordination number of hydroxypyridonate-based gadolinium complexes: implications for MRI contrast agents.
Journal of the American Chemical Society 2006;128(16):5344-5.
2006: Benedetta Bussolati; Cristina Grange; Stefania Bruno; stefano buttiglieri; Maria Chiara Deregibus; Lorenzo Tei; Silvio Aime; Giovanni Camussi
Neural-cell adhesion molecule (NCAM) expression by immature and tumor-derived endothelial cells favors cell organization into capillary-like structures.
Experimental cell research 2006;312(6):913-24.
2006: Silvio Aime; Eliana Gianolio; Giovanni Palmisano; Bruna Robaldo; Alessandro Barge; Luisa Boffa; Giancarlo Cravotto
Improved syntheses of bis(beta-cyclodextrin) derivatives, new carriers for gadolinium complexes.
Organic & biomolecular chemistry 2006;4(6):1124-30.
2006: David A Fulton; Elisa M Elemento; Silvio Aime; Linda Chaabane; Mauro Botta; David Parker
Glycoconjugates of gadolinium complexes for MRI applications.
Chemical communications (Cambridge, England) 2006;(10):1064-6.
2006: Enzo Terreno; Simonetta Geninatti Crich; Simona Belfiore; Livia Biancone; Claudia Cabella; Giovanna Esposito; Andrea D Manazza; Silvio Aime
Effect of the intracellular localization of a Gd-based imaging probe on the relaxation enhancement of water protons.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(3):491-7.
2006: Silvio Aime; Roberto Gobetto; Francesca Reineri; Daniel Canet
Polarization transfer from para-hydrogen to heteronuclei: effect of H/D substitution. The case of AA'X and A2A2'X spin systems.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2006;178(2):184-92.
2006: Claudia Cabella; Simonetta Geninatti Crich; Davide Corpillo; Alessandro Barge; Cristina Ghirelli; E Bruno; V Lorusso; F Uggeri; Silvio Aime
Cellular labeling with Gd(III) chelates: only high thermodynamic stabilities prevent the cells acting as 'sponges' of Gd3+ ions.
Contrast media & molecular imaging 2006;1(1):23-9.
2006: Olga Vasalatiy; Piyu Zhao; Shanrong Zhang; Silvio Aime; A Dean Sherry
Catalytic effects of apoferritin interior surface residues on water proton exchange in lanthanide complexes.
Contrast media & molecular imaging 2006;1(1):10-4.
2005: Silvio Aime; Erik Bruno; Claudia Cabella; Sebastiano Colombatto; Giuseppe Digilio; Valentina Mainero
HR-MAS of cells: A "cellular water shift" due to water-protein interactions?
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(6):1547-52.
2005: Silvio Aime; Walter Dastrù; Roberto Gobetto; Alessandra Viale
para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents.
Organic & biomolecular chemistry 2005;3(21):3948-54.
2005: Enzo Terreno; Mauro Botta; Patrizia Boniforte; Chiara Bracco; Luciano Milone; Bruna Mondino; Fulvio Uggeri; Silvio Aime
A multinuclear NMR relaxometry study of ternary adducts formed between heptadentate Gd(III) chelates and L-lactate.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(19):5531-7.
2005: Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Highly sensitive MRI chemical exchange saturation transfer agents using liposomes.
Angewandte Chemie (International ed. in English) 2005;44(34):5513-5.
2005: Jakub Rudovsky; Petr Hermann; Mauro Botta; Silvio Aime; Ivan Lukes
Dendrimeric Gd(III) complex of a monophosphinated DOTA analogue: optimizing relaxivity by reducing internal motion.
Chemical communications (Cambridge, England) 2005;(18):2390-2.
2005: Silvio Aime; Eliana Gianolio; Dario Longo; Roberto Pagliarin; Clara Lovazzano; Massimo Sisti
New insights for pursuing high relaxivity MRI agents from modelling the binding interaction of Gd(III) chelates to HSA.
Chembiochem : a European journal of chemical biology 2005;6(5):818-20.
2005: Silvio Aime; Luisella Calabi; Luca Biondi; Mario De Miranda; Stefano Ghelli; Lino Paleari; Cristina Rebaudengo; Enzo Terreno
Iopamidol: Exploring the potential use of a well-established x-ray contrast agent for MRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;53(4):830-4.
2005: Silvio Aime; Carla Carrera; Daniela Delli Castelli; Simonetta Geninatti Crich; Enzo Terreno
Tunable imaging of cells labeled with MRI-PARACEST agents.
Angewandte Chemie (International ed. in English) 2005;44(12):1813-5.
2005: David A Fulton; Mark O'Halloran; David Parker; Kanthi Senanayake; Mauro Botta; Silvio Aime
Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates.
Chemical communications (Cambridge, England) 2005;(4):474-6.
2005: Jakub Rudovský; Jan Kotek; Petr Hermann; Ivan Lukes; Valentina Mainero; Silvio Aime
Synthesis of a bifunctional monophosphinic acid DOTA analogue ligand and its lanthanide(III) complexes. A gadolinium(III) complex endowed with an optimal water exchange rate for MRI applications.
Organic & biomolecular chemistry 2005;3(1):112-7.
2005: Caterina Canavese; Cristina Mereu; Maurizio Nordio; Enrico Sabbioni; Silvio Aime
Blast from the past: the aluminum's ghost on the lanthanum salts.
Current medicinal chemistry 2005;12(14):1631-6.
2005: Simonetta Geninatti Crich; Stefania Lanzardo; Alessandro Barge; Giovanna Esposito; Lorenzo Tei; Guido Forni; Silvio Aime
Visualization through magnetic resonance imaging of DNA internalized following "in vivo" electroporation.
Molecular imaging 2005;4(1):7-17.
2005: Simonetta Geninatti Crich; Alessandro Barge; Elisa Battistini; Claudia Cabella; Sara Coluccia; Dario Longo; Valentina Mainero; Guido Tarone; Silvio Aime
Magnetic resonance imaging visualization of targeted cells by the internalization of supramolecular adducts formed between avidin and biotinylated Gd3+ chelates.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2005;10(1):78-86.
2005: Silvio Aime; Alessandro Barge; Eliana Gianolio; Roberto Pagliarin; L Silengo; Lorenzo Tei
High relaxivity contrast agents for MRI and molecular imaging.
Ernst Schering Research Foundation workshop 2005;(49):99-121.
2004: Marlon K Thompson; Dan M J Doble; Luke S Tso; Serena Barra; Mauro Botta; Silvio Aime; Kenneth N Raymond
Hetero-tripodal hydroxypyridonate gadolinium complexes: syntheses, relaxometric properties, water exchange dynamics, and human serum albumin binding.
Inorganic chemistry 2004;43(26):8577-86.
2004: Silvio Aime; Alessandro Barge; Claudia Cabella; Simonetta Geninatti Crich; Eliana Gianolio
Targeting cells with MR imaging probes based on paramagnetic Gd(III) chelates.
Current pharmaceutical biotechnology 2004;5(6):509-18.
2004: Silvio Aime; Luisella Calabi; Camilla Cavallotti; Eliana Gianolio; Giovanni B Giovenzana; Pietro Losi; Alessandro Maiocchi; Giovanni Palmisano; Massimo Sisti
[Gd-AAZTA]-: a new structural entry for an improved generation of MRI contrast agents.
Inorganic chemistry 2004;43(24):7588-90.
2004: Davide Corpillo; Claudia Cabella; Simonetta Geninatti Crich; Alessandro Barge; Silvio Aime
Detection and quantification of lanthanide complexes in cell lysates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Analytical chemistry 2004;76(20):6012-6.
2004: Luca Frullano; Jan Rohovec; Silvio Aime; Thomas Maschmeyer; M I M Prata; J J Pedroso de Lima; Carlos F G C Geraldes; Joop A Peters
Towards targeted MRI: new MRI contrast agents for sialic acid detection.
Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(20):5205-17.
2004: Simonetta Geninatti Crich; Livia Biancone; Vincenzo Cantaluppi; Debora Duò; Giovanna Esposito; Simona Russo; Giovanni Camussi; Silvio Aime
Improved route for the visualization of stem cells labeled with a Gd-/Eu-chelate as dual (MRI and fluorescence) agent.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;51(5):938-44.
2004: Silvio Aime; Camilla Cavallotti; Eliana Gianolio; Giovanni B Giovenzana; Giovanni Palmisano; Massimo Sisti
Mannich reaction as a new route to pyridine-based polyaminocarboxylic ligands.
Organic letters 2004;6(8):1201-4.
2004: Enzo Terreno; Daniela Delli Castelli; Giancarlo Cravotto; Luciano Milone; Silvio Aime
Ln(III)-DOTAMGly complexes: a versatile series to assess the determinants of the efficacy of paramagnetic chemical exchange saturation transfer agents for magnetic resonance imaging applications.
Investigative radiology 2004;39(4):235-43.
2004: Davide Corpillo; Giulia Gardini; Anna Maria Vaira; Manuela Basso; Silvio Aime; Gian Paolo Accotto; Mauro Fasano
Proteomics as a tool to improve investigation of substantial equivalence in genetically modified organisms: the case of a virus-resistant tomato.
Proteomics 2004;4(1):193-200.
2003: Caterina Canavese; Cristina Mereu; Maurizio Nordio; Enrico Sabbioni; Silvio Aime
Where have all the lanthanum salts gone, long time passing?
Kidney international 2003;64(6):2327-8; author reply 2328.
2003: Marlon K Thompson; Mauro Botta; Gaëlle Nicolle; Lothar Helm; Silvio Aime; André E Merbach; Kenneth N Raymond
A highly stable gadolinium complex with a fast, associative mechanism of water exchange.
Journal of the American Chemical Society 2003;125(47):14274-5.
2003: Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Supramolecular adducts between poly-L-arginine and [TmIIIdotp]: a route to sensitivity-enhanced magnetic resonance imaging-chemical exchange saturation transfer agents.
Angewandte Chemie (International ed. in English) 2003;42(37):4527-9.
2003: Enzo Terreno; Mauro Botta; Franco Fedeli; Bruna Mondino; Luciano Milone; Silvio Aime
Enantioselective recognition between chiral alpha-hydroxy-carboxylates and macrocyclic heptadentate lanthanide(III) chelates.
Inorganic chemistry 2003;42(16):4891-7.
2003: Silvio Aime; Giuseppe Digilio; Erik Bruno; Valentina Mainero; Simona Baroni; Mauro Fasano
Modulation of the antioxidant activity of HO* scavengers by albumin binding: a 19F-NMR study.
Biochemical and biophysical research communications 2003;307(4):962-6.
2003: Jan Rohovec; Thomas Maschmeyer; Silvio Aime; Joop A Peters
The structure of the sugar residue in glycated human serum albumin and its molecular recognition by phenylboronate.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(10):2193-9.
2003: Mauro Botta; Silvio Aime; Alessandro Barge; Gabriella Bobba; Rachel S Dickins; David Parker; Enzo Terreno
Ternary complexes between cationic GdIII chelates and anionic metabolites in aqueous solution: an NMR relaxometric study.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(9):2102-9.
2003: Mauro Fasano; Simona Baroni; Silvio Aime; Marco Mattu; Paolo Ascenzi
Determination of ferric heme-human serum albumin by 1H NMR relaxometry.
Journal of inorganic biochemistry 2003;95(1):64-7.
2003: Brendon O'Sullivan; Dan M J Doble; Marlon K Thompson; Carsten Siering; Jide Xu; Mauro Botta; Silvio Aime; Kenneth N Raymond
The effect of ligand scaffold size on the stability of tripodal hydroxypyridonate gadolinium complexes.
Inorganic chemistry 2003;42(8):2577-83.
2003: Giuseppe Digilio; Luca Barbero; Chiara Bracco; Davide Corpillo; Pierandrea Esposito; Gilles Piquet; Silvio Traversa; Silvio Aime
NMR structure of two novel polyethylene glycol conjugates of the human growth hormone-releasing factor, hGRF(1-29)-NH2.
Journal of the American Chemical Society 2003;125(12):3458-70.
2003: Franco Benetollo; Gabriella Bombieri; Luisella Calabi; Silvio Aime; M Botta
Structural variations across the lanthanide series of macrocyclic DOTA complexes: insights into the design of contrast agents for magnetic resonance imaging.
Inorganic chemistry 2003;42(1):148-57.
2003: Elena Peira; Pasquina Marzola; Valerio Podio; Silvio Aime; Andrea Sbarbati; Maria Rosa Gasco
In vitro and in vivo study of solid lipid nanoparticles loaded with superparamagnetic iron oxide.
Journal of drug targeting 2003;11(1):19-24.
2003: Silvio Aime; Alessandro Barge; Mauro Botta; Enzo Terreno
Interactions of lanthanides and their complexes with proteins. Conclusions regarding magnetic resonance imaging.
Metal ions in biological systems 2003;40():643-82.
2002: Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Novel pH-reporter MRI contrast agents.
Angewandte Chemie (International ed. in English) 2002;41(22):4334-6.
2002: Rachel S Dickins; Silvio Aime; Andrei S Batsanov; Andrew Beeby; Mauro Botta; James I Bruce; Judith A K Howard; Christine S Love; David Parker; Robert D Peacock; Horst Puschmann
Structural, luminescence, and NMR studies of the reversible binding of acetate, lactate, citrate, and selected amino acids to chiral diaqua ytterbium, gadolinium, and europium complexes.
Journal of the American Chemical Society 2002;124(43):12697-705.
2002: Silvio Aime; Claudia Cabella; Sebastiano Colombatto; Simonetta Geninatti Crich; Eliana Gianolio; Fabio Maggioni
Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations.
Journal of magnetic resonance imaging : JMRI 2002;16(4):394-406.
2002: Enrico Monzani; Maria Curto; Monica Galliano; Lorenzo Minchiotti; Silvio Aime; Simona Baroni; Mauro Fasano; Angela Amoresano; Anna Maria Salzano; Piero Pucci; Luigi Casella
Binding and relaxometric properties of heme complexes with cyanogen bromide fragments of human serum albumin.
Biophysical journal 2002;83(4):2248-58.
2002: Mauro Bottamauro; Umberto Casellato; Cristina Scalco; Sergio Tamburini; Patrizi Tomasin; Pietro A Vigato; Silvio Aime; Alessandro Barge
Heterodinuclear Ln[bond]Na complexes with an asymmetrical macrocyclic compartmental Schiff base.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(17):3917-26.
2002: Silvio Aime; Daniela Delli Castelli; Franco Fedeli; Enzo Terreno
A paramagnetic MRI-CEST agent responsive to lactate concentration.
Journal of the American Chemical Society 2002;124(32):9364-5.
2002: Silvio Aime; Nicola D'Amelio; Marco Fragai; Yong-Min Lee; Claudio Luchinat; Enzo Terreno; Gianni Valensin
A paramagnetic probe to localize residues next to carboxylates on protein surfaces.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2002;7(6):617-22.
2002: Silvio Aime; Alessandro Barge; Andrei S Batsanov; Mauro Botta; Daniela Delli Castelli; Franco Fedeli; Armando Mortillaro; David Parker; Horst Puschmann
Controlling the variation of axial water exchange rates in macrocyclic lanthanide(III) complexes.
Chemical communications (Cambridge, England) 2002;(10):1120-1.
2002: Giuseppe Digilio; Chiara Bracco; Luca Barbero; Daniela Chicco; Maria Dorly Del Curto; Pierandrea Esposito; Silvio Traversa; Silvio Aime
NMR conformational analysis of antide, a potent antagonist of the gonadotropin releasing hormone.
Journal of the American Chemical Society 2002;124(13):3431-42.
2002: Silvio Aime; Alessandro Barge; Daniela Delli Castelli; Franco Fedeli; Armando Mortillaro; Flemming U Nielsen; Enzo Terreno
Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;47(4):639-48.
2002: Silvio Aime; Luca Frullano; Simonetta Geninatti Crich
Compartmentalization of a gadolinium complex in the apoferritin cavity: a route to obtain high relaxivity contrast agents for magnetic resonance imaging.
Angewandte Chemie (International ed. in English) 2002;41(6):1017-9.
2002: Fabrice Yerly; Kenneth I Hardcastle; Lothar Helm; Silvio Aime; Mauro Botta; André E Merbach
Molecular dynamics simulation of [Gd(egta)(H(2)O)](-) in aqueous solution: internal motions of the poly(amino carboxylate) and water ligands, and rotational correlation times.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(5):1031-9.
2002: Silvio Aime; Walter Dastrù; Simonetta Geninatti Crich; Eliana Gianolio; Valentina Mainero
Innovative magnetic resonance imaging diagnostic agents based on paramagnetic Gd(III) complexes.
Biopolymers 2002;66(6):419-28.
2002: Silvio Aime; Lucio Anelli; Mauro Botta; Marino Brocchetta; Simonetta Canton; Franco Fedeli; Eliana Gianolio; Enzo Terreno
Relaxometric evaluation of novel manganese(II) complexes for application as contrast agents in magnetic resonance imaging.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2002;7(1-2):58-67.
2002: Silvio Aime; Mauro Botta; Valentina Mainero; Enzo Terreno
Separation of intra- and extracellular lactate NMR signals using a lanthanide shift reagent.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;47(1):10-3.
2001: Silvio Aime; I M Botta; Franco Fedeli; Eliana Gianolio; Enzo Terreno; Pier Lucio Anelli
High-Relaxivity contrast agents for magnetic resonance imaging based on multisite interactions between a beta-cyclodextrin oligomer and suitably functionalized GdIII chelates.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(24):5261-9.
2001: C J Sunderland; Mauro Botta; Silvio Aime; Kenneth N Raymond
6-carboxamido-5,4-hydroxypyrimidinones: a new class of heterocyclic ligands and their evaluation as gadolinium chelating agents.
Inorganic chemistry 2001;40(26):6746-56.
2001: Simona Baroni; Marco Mattu; Alessandro Vannini; R Cipollone; Silvio Aime; Paolo Ascenzi; Mauro Fasano
Effect of ibuprofen and warfarin on the allosteric properties of haem-human serum albumin. A spectroscopic study.
European journal of biochemistry / FEBS 2001;268(23):6214-20.
2001: Dan M J Doble; Mauro Botta; J Wang; Silvio Aime; A Barge; Kenneth N Raymond
Optimization of the relaxivity of MRI contrast agents: effect of poly(ethylene glycol) chains on the water-exchange rates of Gd(III) complexes.
Journal of the American Chemical Society 2001;123(43):10758-9.
2001: MP Lowe; David Parker; O Reany; Silvio Aime; Mauro Botta; Giancarlo Castellano; Eliana Gianolio; Roberto Pagliarin
pH-dependent modulation of relaxivity and luminescence in macrocyclic gadolinium and europium complexes based on reversible intramolecular sulfonamide ligation.
Journal of the American Chemical Society 2001;123(31):7601-9.
2001: Mauro Fasano; Simona Baroni; Alessandro Vannini; Paolo Ascenzi; Silvio Aime
Relaxometric characterization of human hemalbumin.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2001;6(5-6):650-8.
2001: Shanrong Zhang; Zoltan Kovacs; S Burgess; Silvio Aime; E Terreno; A Dean Sherry
[DOTA-bis(amide)]lanthanide complexes: NMR evidence for differences in water-molecule exchange rates for coordination isomers.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(1):288-96.
2000: SM Cohen; Jide Xu; E Radkov; Kenneth N Raymond; Mauro Botta; A Barge; Silvio Aime
Syntheses and relaxation properties of mixed gadolinium hydroxypyridinonate MRI contrast agents.
Inorganic chemistry 2000;39(25):5747-56.
2000: Silvio Aime; Mauro Botta; Luca Frullano; Simonetta Geninatti Crich; Giovanni B Giovenzana; Roberto Pagliarin; Giovanni Palmisano; F R Sirtori; Massimo Sisti
[GdPCP2A(H(2)O)(2)](-): a paramagnetic contrast agent designed for improved applications in magnetic resonance imaging.
Journal of medicinal chemistry 2000;43(21):4017-24.
2000: Leonardo Lopiano; Mauro Fasano; Sabrina Giraudo; Giuseppe Digilio; S H Koenig; Elena Torre; Bruno Bergamasco; Silvio Aime
Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.
Neurochemistry international 2000;37(4):331-6.
2000: Silvio Aime; Bruno Bergamasco; M Casu; Giuseppe Digilio; Mauro Fasano; Sabrina Giraudo; Leonardo Lopiano
Isolation and 13C-NMR characterization of an insoluble proteinaceous fraction from substantia nigra of patients with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2000;15(5):977-81.
2000: Silvio Aime; Eliana Gianolio; Enzo Terreno; Giovanni B Giovenzana; Roberto Pagliarin; Massimo Sisti; Giovanni Palmisano; Mauro Botta; MP Lowe; David Parker
Ternary Gd(III)L-HSA adducts: evidence for the replacement of inner-sphere water molecules by coordinating groups of the protein. Implications for the design of contrast agents for MRI.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2000;5(4):488-97.
2000: Silvio Aime; Mauro Botta; E Garino; Simonetta Geninatti Crich; Giovanni B Giovenzana; Roberto Pagliarin; Giovanni Palmisano; Massimo Sisti
Non-covalent conjugates between cationic polyamino acids and GdIII chelates: a route for seeking accumulation of MRI-contrast agents at tumor targeting sites.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(14):2609-17.
1999: Silvio Aime; M Chiaussa; Giuseppe Digilio; Eliana Gianolio; Enzo Terreno
Contrast agents for magnetic resonance angiographic applications: 1H and 17O NMR relaxometric investigations on two gadolinium(III) DTPA-like chelates endowed with high binding affinity to human serum albumin.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 1999;4(6):766-74.
1999: Silvio Aime; S Calzoni; Giuseppe Digilio; Sabrina Giraudo; Mauro Fasano; D Maffeo
A novel 19F-NMR method for the investigation of the antioxidant capacity of biomolecules and biofluids.
Free radical biology & medicine 1999;27(3-4):356-63.
1999: Silvio Aime; Giuseppe Digilio; Mauro Fasano; S Paoletti; A Arnelli; Paolo Ascenzi
Metal complexes as allosteric effectors of human hemoglobin: an NMR study of the interaction of the gadolinium(III) bis(m-boroxyphenylamide)diethylenetriaminepentaacetic acid complex with human oxygenated and deoxygenated hemoglobin.
Biophysical journal 1999;76(5):2735-43.
1999: Silvio Aime; Mauro Botta; Simonetta Geninatti Crich; Giovanni B Giovenzana; Giovanni Palmisano; Massimo Sisti
Novel paramagnetic macromolecular complexes derived from the linkage of a macrocyclic Gd(III) complex to polyamino acids through a squaric acid moiety.
Bioconjugate chemistry 1999;10(2):192-9.
1998: Silvio Aime; Mauro Fasano; S Paoletti; A Bellelli; M Coletta; Paolo Ascenzi
Stabilization of the T-state of ferrous human adult and fetal hemoglobin by Ln(III) complexes: a thermodynamic study.
Journal of inorganic biochemistry 1998;71(1-2):37-43.
1998: Silvio Aime; M Bettinelli; M Ferrari; E Razzano; Enzo Terreno
NMR and luminescence studies on the formation of ternary adducts between HSA and Ln(III)-malonate complexes.
Biochimica et biophysica acta 1998;1385(1):7-16.
1998: Silvia Morel; E Terreno; Elena Ugazio; Silvio Aime; Maria Rosa Gasco
NMR relaxometric investigations of solid lipid nanoparticles (SLN) containing gadolinium(III) complexes.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1998;45(2):157-63.
1997: Silvio Aime; Bruno Bergamasco; D Biglino; Giuseppe Digilio; Mauro Fasano; Elio Giamello; Leonardo Lopiano
EPR investigations of the iron domain in neuromelanin.
Biochimica et biophysica acta 1997;1361(1):49-58.
1996: Silvio Aime; Mauro Fasano; S Paoletti; Franca Viola; C Tarricone; Paolo Ascenzi
1H-NMR relaxometric study of pancreatic serine (pro)enzyme inhibition by a Gd(III) chelate bearing boronic functionalities.
Biochemistry and molecular biology international 1996;39(4):741-6.
1996: Franca Viola; Silvio Aime; Massimo Coletta; Alessandro Desideri; Mauro Fasano; S Paoletti; C Tarricone; Paolo Ascenzi
Azide, cyanide, fluoride, imidazole and pyridine binding to ferric and ferrous native horse heart cytochrome c and to its carboxymethylated derivative: a comparative study.
Journal of inorganic biochemistry 1996;62(3):213-22.
1996: Silvio Aime; M Botta; Mauro Fasano; Enzo Terreno; P Kinchesh; L Calabi; L Paleari
A new ytterbium chelate as contrast agent in chemical shift imaging and temperature sensitive probe for MR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1996;35(5):648-51.
1996: Silvio Aime; Mauro Fasano; S Paoletti; Francesca Cutruzzolà; Alessandro Desideri; M Bolognesi; M Rizzi; Paolo Ascenzi
Structural determinants of fluoride and formate binding to hemoglobin and myoglobin: crystallographic and 1H-NMR relaxometric study.
Biophysical journal 1996;70(1):482-8.
1996: Silvio Aime; Mauro Fasano; Bruno Bergamasco; L Lopiano; G Quattrocolo
Nuclear magnetic resonance spectroscopy characterization and iron content determination of human mesencephalic neuromelanin.
Advances in neurology 1996;69():263-70.
1995: Silvio Aime; Mauro Fasano; S Paoletti; A Arnelli; Paolo Ascenzi
NMR relaxometric investigation on human methemoglobin and fluoromethemoglobin. An improved quantitative in vitro assay of human methemoglobin.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1995;33(6):827-31.
1994: Silvio Aime; Mauro Fasano; Bruno Bergamasco; L Lopiano; G Valente
Evidence for a glycidic-lipidic matrix in human neuromelanin, potentially responsible for the enhanced iron sequestering ability of substantia nigra.
Journal of neurochemistry 1994;62(1):369-71.
1993: Silvio Aime; M Botta; Enzo Terreno; Pier Lucio Anelli; Fulvio Uggeri
Gd(DOTP)5-outer-sphere relaxation enhancement promoted by nitrogen bases.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1993;30(5):583-91.
1992: Silvio Aime; W Dastrú; Mauro Fasano; A Arnelli; M Castagnola; B Giardina; Paolo Ascenzi
Quantitative determination of methemoglobin by measuring the solvent-water proton-nuclear magnetic resonance relaxation rate.
Clinical chemistry 1992;38(12):2401-4.
1992: Silvio Aime; M Botta; G Ermondi; Mauro Fasano; Enzo Terreno
Paramagnetic water proton relaxation enhancement: from contrast agents in MRI to reagents for quantitative "in vitro" assays.
Magnetic resonance imaging 1992;10(5):849-54.
1991: Silvio Aime; Mauro Fasano; Enzo Terreno; C J Groombridge
NMR studies of melanins: characterization of a soluble melanin free acid from Sepia ink.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1991;4(5-6):216-21.
1991: Silvio Aime; Mauro Fasano; Enzo Terreno; Corrado Sarzanini; Edoardo Mentasti
An NMR study of the interaction between melanin free acid and Mn2+ ions as a model to mimic the enhanced proton relaxation rates in melanotic melanoma.
Magnetic resonance imaging 1991;9(6):963-8.
1989: Silvio Aime; M Botta; I Camurati
NMR studies of L-dopa melanin-manganese(II) complex in water solution.
Journal of inorganic biochemistry 1989;36(1):1-9.
1988: Silvio Aime; R Nano; M Grandi
A new class of contrast agents for magnetic resonance imaging based on selective reduction of water-T2 by chemical exchange.
Investigative radiology 1988;23 Suppl 1():S267-70.
1988: Silvio Aime; R Nano
Factors determining the proton T1 relaxivity in solutions containing Gd-DTPA.
Investigative radiology 1988;23 Suppl 1():S264-6.
1988: Silvio Aime; P R Crippa
13C solid-state cross polarization/magic-angle-spinning nuclear magnetic resonance spectra of natural and synthetic melanins.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1988;1(5):355-7.