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Nobuhisa Ueda

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Atsuko Ikenouchi-Sugita; Nakao Iwata; Asuka Katsuki; Taro Kishi; Kenji Hayashi; Hikaru Hori; Nobuhisa Ueda; Wakako Umene-Nakano; Reiji Yoshimura; Jun Nakamura
Three polymorphisms of the eNOS gene and plasma levels of metabolites of nitric oxide in depressed Japanese patients: a preliminary report.
N Goto; Reiji Yoshimura; Shingo Kakeda; Junji Moriya; K Hayashi; A Ikenouchi-Sugita; W Umene-Nakano; Hikaru Hori; Nobuhisa Ueda; Yukunori Korogi; Jun Nakamura
Comparison of brain N-acetylaspartate levels and serum brain-derived neurotrophic factor (BDNF) levels between patients with first-episode schizophrenia psychosis and healthy controls.
Wakako Umene-Nakano; Reiji Yoshimura; Nobuhisa Ueda; Akihito Suzuki; Atsuko Ikenouchi-Sugita; Hikaru Hori; Koichi Otani; Jun Nakamura
Predictive factors for responding to sertraline treatment: views from plasma catecholamine metabolites and serotonin transporter polymorphism.

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All Publications

2011: Atsuko Ikenouchi-Sugita; Nakao Iwata; Asuka Katsuki; Taro Kishi; Kenji Hayashi; Hikaru Hori; Nobuhisa Ueda; Wakako Umene-Nakano; Reiji Yoshimura; Jun Nakamura
Three polymorphisms of the eNOS gene and plasma levels of metabolites of nitric oxide in depressed Japanese patients: a preliminary report.
Human psychopharmacology 2011;26(7):531-4.
2011: N Goto; Reiji Yoshimura; Shingo Kakeda; Junji Moriya; K Hayashi; A Ikenouchi-Sugita; W Umene-Nakano; Hikaru Hori; Nobuhisa Ueda; Yukunori Korogi; Jun Nakamura
Comparison of brain N-acetylaspartate levels and serum brain-derived neurotrophic factor (BDNF) levels between patients with first-episode schizophrenia psychosis and healthy controls.
European psychiatry : the journal of the Association of European Psychiatrists 2011;26(1):57-63.
2010: Wakako Umene-Nakano; Reiji Yoshimura; Nobuhisa Ueda; Akihito Suzuki; Atsuko Ikenouchi-Sugita; Hikaru Hori; Koichi Otani; Jun Nakamura
Predictive factors for responding to sertraline treatment: views from plasma catecholamine metabolites and serotonin transporter polymorphism.
Journal of psychopharmacology (Oxford, England) 2010;24(12):1764-71.
2010: Reiji Yoshimura; Atsuko Ikenouchi-Sugita; Hikaru Hori; Wakako Umene-Nakano; Asuka Katsuki; Kenji Hayashi; Kiyokazu Atake; Nobuhisa Ueda; Jun Nakamura
[Brain-derived neurotrophic factor (BDNF) and mood disorder].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 2010;30(5-6):181-4.
2010: Reiji Yoshimura; Wakako Umene-Nakano; Nobuhisa Ueda; Atsuko Ikenouchi-Sugita; Hikaru Hori; Asuka Katsuki; Kenji Hayashi; Kyoko Miyamoto; Yuki Kodama; Jun Nakamura
No difference in adherence to paroxetine between depressed patients with early remission and those with late remission based on monitoring of plasma paroxetine concentrations.
Human psychopharmacology 2010;25(6):487-90.
2010: Naoki Goto; Reiji Yoshimura; Junji Moriya; Shingo Kakeda; Kenji Hayashi; Nobuhisa Ueda; Atsuko Ikenouchi-Sugita; Wakako Umene-Nakano; Norihiro Oonari; Yukunori Korogi; Jun Nakamura
Critical examination of a correlation between brain gamma-aminobutyric acid (GABA) concentrations and a personality trait of extroversion in healthy volunteers as measured by a 3 Tesla proton magnetic resonance spectroscopy study.
Psychiatry research 2010;182(1):53-7.
2010: Reiji Yoshimura; Atsuko Ikenouchi-Sugita; Hikaru Hori; Wakako Umene-Nakano; Asuka Katsuki; Kenji Hayashi; Nobuhisa Ueda; Jun Nakamura
Adding a low dose atypical antipsychotic drug to an antidepressant induced a rapid increase of plasma brain-derived neurotrophic factor levels in patients with treatment-resistant depression.
Progress in neuro-psychopharmacology & biological psychiatry 2010;34(2):308-12.
2010: Reiji Yoshimura; Nobuhisa Ueda; Hikaru Hori; Atsuko Ikenouchi-Sugita; Wakako Umene-Nakano; Jun Nakamura
Different patterns of longitudinal changes in plasma levels of catecholamine metabolites and brain-derived neurotrophic factor after administration of atypical antipsychotics in first episode untreated schizophrenic patients.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2010;11(2 Pt 2):256-61.
2010: Yuichiro Nakano; Reiji Yoshimura; Hideki Nakano; Atsuko Ikenouchi-Sugita; Hikaru Hori; Wakako Umene-Nakano; Nobuhisa Ueda; Jun Nakamura
Association between plasma nitric oxide metabolites levels and negative symptoms of schizophrenia: a pilot study.
Human psychopharmacology 2010;25(2):139-44.
2010: Reiji Yoshimura; Atsuko Ikenouchi-Sugita; Hikaru Hori; Wakako Umene-Nakano; Kenji Hayashi; Asuka Katsuki; Nobuhisa Ueda; Jun Nakamura
[Blood levels of brain-derived neurotrophic factor (BDNF) in major depressive disorder].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 2010;112(10):982-5.
2009: Naoki Goto; Reiji Yoshimura; Shingo Kakeda; Junji Moriya; Kenji Hayashi; Atsuko Ikenouchi-Sugita; Wakako Umene-Nakano; Hikaru Hori; Nobuhisa Ueda; Yukunori Korogi; Jun Nakamura
Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia.
Human psychopharmacology 2009;24(8):639-45.
2009: Atsuko Ikenouchi-Sugita; Reiji Yoshimura; Hikaru Hori; Wakako Umene-Nakano; Nobuhisa Ueda; Jun Nakamura
Effects of antidepressants on plasma metabolites of nitric oxide in major depressive disorder: comparison between milnacipran and paroxetine.
Progress in neuro-psychopharmacology & biological psychiatry 2009;33(8):1451-3.
2009: Reiji Yoshimura; Wakako Umene-Nakano; Akihito Suzuki; Nobuhisa Ueda; Kyoko Miyamoto; Atsuko Ikenouchi-Sugita; Hikaru Hori; Koichi Otani; Jun Nakamura
Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients.
Human psychopharmacology 2009;24(6):489-94.
2009: Wakako Umene-Nakano; Reiji Yoshimura; Atsuko Ikenouchi-Sugita; Hikaru Hori; Kenji Hayashi; Nobuhisa Ueda; Jun Nakamura
Serum levels of brain-derived neurotrophic factor in comorbidity of depression and alcohol dependence.
Human psychopharmacology 2009;24(5):409-13.
2009: Naoki Goto; Reiji Yoshimura; Junji Moriya; Shingo Kakeda; Nobuhisa Ueda; Atsuko Ikenouchi-Sugita; Wakako Umene-Nakano; Kenji Hayashi; Norihiro Oonari; Yukunori Korogi; Jun Nakamura
Reduction of brain gamma-aminobutyric acid (GABA) concentrations in early-stage schizophrenia patients: 3T Proton MRS study.
Schizophrenia research 2009;112(1-3):192-3.
2009: Reiji Yoshimura; Hikaru Hori; Atsuko Ikenouchi-Sugita; Wakako Umene-Nakano; Nobuhisa Ueda; Jun Nakamura
Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression.
Progress in neuro-psychopharmacology & biological psychiatry 2009;33(4):722-6.
2009: Hikaru Hori; Nobuhisa Ueda; Reiji Yoshimura; Hiroshi Yamamoto; Kenta Wani; Yoshinori Etoh; Kensuke Haraga; Junichi Kitahara; Jun Nakamura
Olanzapine orally disintegrating tablets (Zyprexa Zydis) rapidly improve excitement components in the acute phase of first-episode schizophrenic patients: an open-label prospective study.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2009;10(4 Pt 3):741-5.
2009: Atsuko Ikenouchi-Sugita; Reiji Yoshimura; Kenji Hayashi; Nobuhisa Ueda; Wakako Umene-Nakano; Hikaru Hori; Jun Nakamura
A case of late-onset Tourette's disorder successfully treated with aripiprazole: view from blood levels of catecholamine metabolites and brain-derived neurotrophic factor (BDNF).
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2009;10(4 Pt 3):977-80.
2009: Nobuhisa Ueda; Reiji Yoshimura; Wakako Umene-Nakano; Atsuko Ikenouchi-Sugita; Hikaru Hori; Kenji Hayashi; Yuki Kodama; Jun Nakamura
Grapefruit juice alters plasma sertraline levels after single ingestion of sertraline in healthy volunteers.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2009;10(4 Pt 3):832-5.
2009: Hikaru Hori; Reiji Yoshimura; Nobuhisa Ueda; Atsuko Ikenouchi-Sugita; Wakako Umene-Nakano; Jun Nakamura
A case with occurring adverse effects when cross-over titration from fluvoxamine to paroxetine associated with increasing the plasma fluvoxamine level in major depressive disorder.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2009;10(4 Pt 2):620-2.
2008: Atsuko Ikenouchi-Sugita; Reiji Yoshimura; Nobuhisa Ueda; Yuki Kodama; Wakako Umene-Nakano; Jun Nakamura
Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes.
Neuropsychiatric disease and treatment 2008;4(6):1277-81.
2008: Reiji Yoshimura; Wakako Umene-Nakano; Nobuhisa Ueda; Atsuko Ikenouchi-Sugita; Hikaru Hori; Jun Nakamura
Addition of risperidone to sertraline improves sertraline-resistant refractory depression without influencing plasma concentrations of sertraline and desmethylsertraline.
Human psychopharmacology 2008;23(8):707-13.
2008: Tatsuya Okamoto; Reiji Yoshimura; Atsuko Ikenouchi-Sugita; Hikaru Hori; Wakako Umene-Nakano; Yoshiaki Inoue; Nobuhisa Ueda; Jun Nakamura
Efficacy of electroconvulsive therapy is associated with changing blood levels of homovanillic acid and brain-derived neurotrophic factor (BDNF) in refractory depressed patients: a pilot study.
Progress in neuro-psychopharmacology & biological psychiatry 2008;32(5):1185-90.
2008: Nobuhisa Ueda; Yuki Kodama; Hikaru Hori; Wakako Umene; Atsuko Sugita; Hideki Nakano; Reiji Yoshimura; Jun Nakamura
Two cases of burning mouth syndrome treated with olanzapine.
Psychiatry and clinical neurosciences 2008;62(3):359-61.
2008: Reiji Yoshimura; Shingo Kakihara; Wakako Umene-Nakano; Atsuko Sugita; Hikaru Hori; Nobuhisa Ueda; Jun Nakamura
Acute risperidone treatment did not increase daily cigarette consumption or plasma levels of cotinine and caffeine: a pilot study.
Human psychopharmacology 2008;23(4):327-32.
2008: Masae Mitoma; Reiji Yoshimura; Atsuko Sugita; Wakako Umene; Hikaru Hori; Hideki Nakano; Nobuhisa Ueda; Jun Nakamura
Stress at work alters serum brain-derived neurotrophic factor (BDNF) levels and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in healthy volunteers: BDNF and MHPG as possible biological markers of mental stress?
Progress in neuro-psychopharmacology & biological psychiatry 2008;32(3):679-85.
2007: Kyoko Miyamoto; Reiji Yoshimura; Nobuhisa Ueda; Atsuko Sugita; Wakako Umene; Hikaru Hori; Masae Mitoma; Jun Nakamura
Effects of acute paroxetine treatment on the consumption of cigarette smoking and caffeine in depressed patients.
Human psychopharmacology 2007;22(7):483-90.
2007: Reiji Yoshimura; Masae Mitoma; Atsuko Sugita; Hikaru Hori; Tatsuya Okamoto; Wakako Umene; Nobuhisa Ueda; Jun Nakamura
Effects of paroxetine or milnacipran on serum brain-derived neurotrophic factor in depressed patients.
Progress in neuro-psychopharmacology & biological psychiatry 2007;31(5):1034-7.
2007: Reiji Yoshimura; Hikaru Hori; Atsuko Sugita; Nobuhisa Ueda; Shingo Kakihara; Wakako Umene; Yuichiro Nakano; Koji Shinkai; Masae Mitoma; Makiko Ohta; Takahiro Shinkai; Jun Nakamura
Treatment with risperidone for 4 weeks increased plasma 3-methoxy-4-hydroxypnenylglycol (MHPG) levels, but did not alter plasma brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients.
Progress in neuro-psychopharmacology & biological psychiatry 2007;31(5):1072-7.
2007: Reiji Yoshimura; Koshiro Tsuji; Nobuhisa Ueda; Jun Nakamura
Increase of plasma brain-derived neurotrophic factor levels in two psychotic depressed patients responding to lithium addition to paroxetine treatment.
Neuropsychiatric disease and treatment 2007;3(5):683-6.
2007: Reiji Yoshimura; Koji Shinkai; Nobuhisa Ueda; Jun Nakamura
Valproic acid improves psychotic agitation without influencing plasma risperidone levels in schizophrenic patients.
Pharmacopsychiatry 2007;40(1):9-13.
2006: Reiji Yoshimura; Yuichiro Nakano; Hikaru Hori; Atsuko Ikenouchi; Nobuhisa Ueda; Jun Nakamura
Effect of risperidone on plasma catecholamine metabolites and brain-derived neurotrophic factor in patients with bipolar disorders.
Human psychopharmacology 2006;21(7):433-8.
2006: Makiko Goto; Reiji Yoshimura; Shingo Kakihara; Koji Shinkai; Yasuhisa Yamada; Kyoko Kaji; Nobuhisa Ueda; Jun Nakamura
Risperidone in the treatment of psychotic depression.
Progress in neuro-psychopharmacology & biological psychiatry 2006;30(4):701-7.
2006: T Yukimasa; Reiji Yoshimura; Akira Tamagawa; Takenori Uozumi; Koji Shinkai; Nobuhisa Ueda; Sadatoshi Tsuji; Jun Nakamura
High-frequency repetitive transcranial magnetic stimulation improves refractory depression by influencing catecholamine and brain-derived neurotrophic factors.
Pharmacopsychiatry 2006;39(2):52-9.
2005: Reiji Yoshimura; Jun Nakamura; Koji Shinkai; Makiko Goto; Yasuhisa Yamada; Kyoko Kaji; Shingo Kakihara; Nobuhisa Ueda; Kimio Kohara; Hideaki Ninomiya; Hideaki Egami; Hisao Maeda
An open study of risperidone liquid in the acute phase of schizophrenia.
Human psychopharmacology 2005;20(4):243-8.
2005: Reiji Yoshimura; Koji Shinkai; Shingo Kakihara; Makiko Goto; Yasuhisa Yamada; Kyoko Kaji; Nobuhisa Ueda; Jun Nakamura
Little effects of low dosage of levomepromazine on plasma risperidone levels.
Pharmacopsychiatry 2005;38(2):98-100.
2005: Shingo Kakihara; Reiji Yoshimura; Koji Shinkai; Chima Matsumoto; Makiko Goto; Kyoko Kaji; Yasuhisa Yamada; Nobuhisa Ueda; Osamu Ohmori; Jun Nakamura
Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6.
International clinical psychopharmacology 2005;20(2):71-8.
2004: Miki Iwakawa; Takeshi Terao; Atsushi Soya; Hideki Kojima; Yoshiaki Inoue; Nobuhisa Ueda; Reiji Yoshimura; Jun Nakamura
A novel antipsychotic, perospirone, has antiserotonergic and antidopaminergic effects in human brain: findings from neuroendocrine challenge tests.
Psychopharmacology 2004;176(3-4):407-11.
2004: Reiji Yoshimura; Jun Nakamura; Koji Shinkai; Nobuhisa Ueda
Clinical response to antidepressant treatment and 3-methoxy-4-hydroxyphenylglycol levels: mini review.
Progress in neuro-psychopharmacology & biological psychiatry 2004;28(4):611-6.
2004: Koji Shinkai; Reiji Yoshimura; Nobuhisa Ueda; Kana Okamoto; Jun Nakamura
Associations between baseline plasma MHPG (3-methoxy-4-hydroxyphenylglycol) levels and clinical responses with respect to milnacipran versus paroxetine treatment.
Journal of clinical psychopharmacology 2004;24(1):11-7.
2003: Nobuhisa Ueda; Takeshi Terao; Osamu Ohmori; Jun Nakamura
Schneiderian first-rank symptoms associated with fluvoxamine treatment: a case report.
Human psychopharmacology 2003;18(6):477-8.
2003: Hideki Kojima; Takeshi Terao; Miki Iwakawa; Atsushi Soya; N Inoue; Y Shiraishi; Y Son; S Soeda; Nobuhisa Ueda; Reiji Yoshimura; Jun Nakamura
Paroxetine as a 5-HT neuroendocrine probe.
Psychopharmacology 2003;167(1):97-102.
2003: Reiji Yoshimura; Nobuhisa Ueda; Koji Shinkai; Jun Nakamura
Plasma levels of homovanillic acid and the response to risperidone in first episode untreated acute schizophrenia.
International clinical psychopharmacology 2003;18(2):107-11.
2003: Nobuhisa Ueda; Reiji Yoshimura; Koji Shinkai; Yumi Sakata; Jun Nakamura
Higher plasma 5-hydroxyindoleacetic acid levels are associated with SSRI-induced nausea.
Neuropsychobiology 2003;48(1):31-4.
2002: Nobuhisa Ueda; Reiji Yoshimura; Koji Shinkai; Jun Nakamura
Plasma levels of catecholamine metabolites predict the response to sulpiride or fluvoxamine in major depression.
Pharmacopsychiatry 2002;35(5):175-81.
2002: Reiji Yoshimura; Nobuhisa Ueda; Jun Nakamura; Seiji Eto; Masakazu Matsushita
Interaction between fluvoxamine and cotinine or caffeine.
Neuropsychobiology 2002;45(1):32-5.
2001: Nobuhisa Ueda; Reiji Yoshimura; Koji Shinkai; Takeshi Terao; Jun Nakamura
Characteristics of fluvoxamine-induced nausea.
Psychiatry research 2001;104(3):259-64.
2001: Jun Nakamura; Reiji Yoshimura; T Okuno; Nobuhisa Ueda; M Hachida; Kosei Yasumoto; H Egami; H Maeda; M Nishi; S Aoyagi
Association of plasma free-3-methoxy-4-hydroxyphenyl (ethylene)glycol, natural killer cell activity and delirium in postoperative patients.
International clinical psychopharmacology 2001;16(6):339-43.
2001: Reiji Yoshimura; Shingo Kakihara; Atsushi Soya; Nobuhisa Ueda; Koji Shinkai; Jun Nakamura
Effect of clonazepam treatment on antipsychotic drug-induced Meige syndrome and changes in plasma levels of GABA, HVA, and MHPG during treatment.
Psychiatry and clinical neurosciences 2001;55(5):543-6.
2001: Nobuhisa Ueda; Jun Nakamura
[Side effects and its countermeasures of antidepressant].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(8):1535-8.
2001: Reiji Yoshimura; Nobuhisa Ueda; Jun Nakamura
Possible relationship between combined plasma concentrations of risperidone plus 9-hydroxyrisperidone and extrapyramidal symptoms. Preliminary study.
Neuropsychobiology 2001;44(3):129-33.
2000: Nobuhisa Ueda; Reiji Yoshimura; S Eto; Takeshi Terao; Jun Nakamura
Delirious episodes induced by intravenous administration of clomipramine associated with an acute increase in its plasma concentrations.
Psychiatry and clinical neurosciences 2000;54(6):669-72.
2000: Reiji Yoshimura; Nobuhisa Ueda; Jun Nakamura
Low dosage of levomepromazine did not increase plasma concentrations of fluvoxamine.
International clinical psychopharmacology 2000;15(4):233-5.
2000: Reiji Yoshimura; Jun Nakamura; Nobuhisa Ueda; Takeshi Terao
Effect of risperidone on plasma free 3-methoxy-4-hydroxyphenylglycol (pMHPG) levels in schizophrenic patients: relationship among plasma concentrations of risperidone and 9-hydroxyrisperidone, pMHPG levels, and clinical improvement.
International clinical psychopharmacology 2000;15(3):175-80.
1999: Takeshi Terao; S Matsuda; H Kojima; K Okuno; H Hori; A Kaku; Nobuhisa Ueda; A Etoh
Incidence and risk factors of benign creatine phosphokinase elevations in chronic psychiatric patients.
Neuropsychobiology 1999;39(4):173-80.