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Iris Ueki

Research Profile

Anatomy

Chemicals & Drugs

Living Beings

Dogs
Rats

Physiology

Leukocyte Chemotaxis

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Publications

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Takashi Nakanaga; Jay A Nadel; Iris F Ueki; Jonathan L Koff; Matt X G Shao
Regulation of interleukin-8 via an airway epithelial signaling cascade.
Jonathan L Koff; Matt X G Shao; Suil Kim; Iris F Ueki; Jay A Nadel
Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.
Kamran Atabai; Rafael Fernandez; Xiaozhu Huang; Iris F Ueki; Ahnika Kline; Yong Li; Sepid Sadatmansoori; Christine Smith-Steinhart; Weimin Zhu; Robert Pytela; Zena Werb; Dean Sheppard
Mfge8 is critical for mammary gland remodeling during involution.

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All Publications

2007: Takashi Nakanaga; Jay A Nadel; Iris F Ueki; Jonathan L Koff; Matt X G Shao
Regulation of interleukin-8 via an airway epithelial signaling cascade.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1289-96.
2006: Jonathan L Koff; Matt X G Shao; Suil Kim; Iris F Ueki; Jay A Nadel
Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8693-700.
2005: Kamran Atabai; Rafael Fernandez; Xiaozhu Huang; Iris F Ueki; Ahnika Kline; Yong Li; Sepid Sadatmansoori; Christine Smith-Steinhart; Weimin Zhu; Robert Pytela; Zena Werb; Dean Sheppard
Mfge8 is critical for mammary gland remodeling during involution.
Molecular biology of the cell 2005;16(12):5528-37.
2004: Pierre-Régis Burgel; Lars-Olaf Cardell; Iris F Ueki; Jay A Nadel
Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(4):594-600.
2003: Sun Tae Kim; Takashi Nakanaga; Iris F Ueki; Jay A Nadel
fMLP causes degranulation followed by regranulation in rat nasal glands.
The Laryngoscope 2003;113(11):1998-2003.
2003: Matt X G Shao; Iris F Ueki; Jay A Nadel
Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11618-23.
2002: K Kohri; Iris F Ueki; Jae Jeong Shim; Pierre-Régis Burgel; Yeon-Mok Oh; Dominic Cheng-Wei Tam; Trang Dao-Pick; Jay A Nadel
Pseudomonas aeruginosa induces MUC5AC production via epidermal growth factor receptor.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;20(5):1263-70.
2002: Kazuhiro Kohri; Iris F Ueki; Jay A Nadel
Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation.
American journal of physiology. Lung cellular and molecular physiology 2002;283(3):L531-40.
2002: Kamran Atabai; Masanobu Ishigaki; Thomas Geiser; Iris F Ueki; Michael A Matthay; Lorraine B Ware
Keratinocyte growth factor can enhance alveolar epithelial repair by nonmitogenic mechanisms.
American journal of physiology. Lung cellular and molecular physiology 2002;283(1):L163-9.
2002: Suil Kim; Jae Jeong Shim; Pierre-Régis Burgel; Iris F Ueki; Trang Dao-Pick; Dominic Cheng-Wei Tam; Jay A Nadel
IL-13-induced Clara cell secretory protein expression in airway epithelium: role of EGFR signaling pathway.
American journal of physiology. Lung cellular and molecular physiology 2002;283(1):L67-75.
2001: Pierre-Régis Burgel; Stephen C Lazarus; Dominic Cheng-Wei Tam; Iris F Ueki; Kamran Atabai; M Birch; Jay A Nadel
Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):5948-54.
2001: HM Lee; L Malm; Karim Dabbagh; Trang Dao-Pick; Iris F Ueki; Suil Kim; Jae Jeong Shim; Jay A Nadel
Epidermal growth factor receptor signaling mediates regranulation of rat nasal goblet cells.
The Journal of allergy and clinical immunology 2001;107(6):1046-50.
2001: K Takeyama; B Jung; Jae Jeong Shim; Pierre-Régis Burgel; Trang Dao-Pick; Iris F Ueki; U Protin; P Kroschel; Jay A Nadel
Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke.
American journal of physiology. Lung cellular and molecular physiology 2001;280(1):L165-72.
2001: Jae Jeong Shim; Karim Dabbagh; Iris F Ueki; Trang Dao-Pick; Pierre-Régis Burgel; K Takeyama; Dominic Cheng-Wei Tam; Jay A Nadel
IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils.
American journal of physiology. Lung cellular and molecular physiology 2001;280(1):L134-40.
2000: Pierre-Régis Burgel; Estelle Escudier; A Coste; Trang Dao-Pick; Iris F Ueki; K Takeyama; Jae Jeong Shim; A H Murr; Jay A Nadel
Relation of epidermal growth factor receptor expression to goblet cell hyperplasia in nasal polyps.
The Journal of allergy and clinical immunology 2000;106(4):705-12.
2000: Jae Jeong Shim; Karim Dabbagh; K Takeyama; Pierre-Régis Burgel; Trang Dao-Pick; Iris F Ueki; Jay A Nadel
Suplatast tosilate inhibits goblet-cell metaplasia of airway epithelium in sensitized mice.
The Journal of allergy and clinical immunology 2000;105(4):739-45.
2000: K Takeyama; Karim Dabbagh; J Jeong Shim; Trang Dao-Pick; Iris F Ueki; Jay A Nadel
Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1546-52.
2000: HM Lee; K Takeyama; Karim Dabbagh; JA Lausier; Iris F Ueki; Jay A Nadel
Agarose plug instillation causes goblet cell metaplasia by activating EGF receptors in rat airways.
American journal of physiology. Lung cellular and molecular physiology 2000;278(1):L185-92.
1999: Karim Dabbagh; K Takeyama; HM Lee; Iris F Ueki; JA Lausier; Jay A Nadel
IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):6233-7.
1999: Véronique Witko-Sarsat; Lise Halbwachs-Mecarelli; A Schuster; Patrick Nusbaum; Iris F Ueki; Sandrine Canteloup; G Lenoir; Béatrice Descamps-Latscha; Jay A Nadel
Proteinase 3, a potent secretagogue in airways, is present in cystic fibrosis sputum.
American journal of respiratory cell and molecular biology 1999;20(4):729-36.
1999: K Takeyama; Karim Dabbagh; HM Lee; C Agustí; JA Lausier; Iris F Ueki; K M Grattan; Jay A Nadel
Epidermal growth factor system regulates mucin production in airways.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3081-6.
1998: C Agusti; K Takeyama; Lars-Olaf Cardell; Iris F Ueki; JA Lausier; YP Lou; Jay A Nadel
Goblet cell degranulation after antigen challenge in sensitized guinea pigs. Role of neutrophils.
American journal of respiratory and critical care medicine 1998;158(4):1253-8.
1998: K Takeyama; C Agustí; Iris F Ueki; JA Lausier; Lars-Olaf Cardell; Jay A Nadel
Neutrophil-dependent goblet cell degranulation: role of membrane-bound elastase and adhesion molecules.
The American journal of physiology 1998;275(2 Pt 1):L294-302.
1998: Lars-Olaf Cardell; Iris F Ueki; Pär Stjärne; C Agusti; K Takeyama; Anders Lindén; Jay A Nadel
Bronchodilatation in vivo by carbon monoxide, a cyclic GMP related messenger.
British journal of pharmacology 1998;124(6):1065-8.
1998: YP Lou; K Takeyama; K M Grattan; JA Lausier; Iris F Ueki; C Agustí; Jay A Nadel
Platelet-activating factor induces goblet cell hyperplasia and mucin gene expression in airways.
American journal of respiratory and critical care medicine 1998;157(6 Pt 1):1927-34.
1998: Lars-Olaf Cardell; YP Lou; K Takeyama; Iris F Ueki; JA Lausier; Jay A Nadel
Carbon monoxide, a cyclic GMP-related messenger, involved in hypoxic bronchodilation in vivo.
Pulmonary pharmacology & therapeutics 1998;11(4):309-15.
1995: H Inoue; M Hara; P P Massion; K M Grattan; JA Lausier; B Chan; T Kaneko; K Isono; P G Jorens; Iris F Ueki
Role of recruited neutrophils in interleukin-8 production in dog trachea after stimulation with Pseudomonas in vivo.
American journal of respiratory cell and molecular biology 1995;13(5):570-7.
1995: T Kaneko; R Alvarez; Iris F Ueki; Jay A Nadel
Elevated intracellular cyclic AMP inhibits chemotaxis in human eosinophils.
Cellular signalling 1995;7(5):527-34.
1995: A Schuster; John V Fahy; Iris F Ueki; Jay A Nadel
Cystic fibrosis sputum induces a secretory response from airway gland serous cells that can be prevented by neutrophil protease inhibitors.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(1):10-4.
1994: H Inoue; P P Massion; Iris F Ueki; K M Grattan; M Hara; A F Dohrman; B Chan; JA Lausier; J A Golden; Jay A Nadel
Pseudomonas stimulates interleukin-8 mRNA expression selectively in airway epithelium, in gland ducts, and in recruited neutrophils.
American journal of respiratory cell and molecular biology 1994;11(6):651-63.
1994: P G Jorens; J B Richman-Eisenstat; B P Housset; P P Massion; Iris F Ueki; Jay A Nadel
Pseudomonas-induced neutrophil recruitment in the dog airway in vivo is mediated in part by IL-8 and inhibited by a leumedin.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(11):1925-31.
1993: P P Massion; C C Funari; Iris F Ueki; S Ikeda; Donald M McDonald; Jay A Nadel
Parainfluenza (Sendai) virus infects ciliated cells and secretory cells but not basal cells of rat tracheal epithelium.
American journal of respiratory cell and molecular biology 1993;9(4):361-70.
1993: J B Richman-Eisenstat; P G Jorens; C A Hébert; Iris F Ueki; Jay A Nadel
Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases.
The American journal of physiology 1993;264(4 Pt 1):L413-8.
1992: P G Jorens; J B Richman-Eisenstat; B P Housset; P D Graf; Iris F Ueki; J Olesch; Jay A Nadel
Interleukin-8 induces neutrophil accumulation but not protease secretion in the canine trachea.
The American journal of physiology 1992;263(6 Pt 1):L708-13.
1992: John V Fahy; A Schuster; Iris F Ueki; Homer A Boushey; Jay A Nadel
Mucus hypersecretion in bronchiectasis. The role of neutrophil proteases.
The American review of respiratory disease 1992;146(6):1430-3.
1992: A Schuster; Iris F Ueki; Jay A Nadel
Neutrophil elastase stimulates tracheal submucosal gland secretion that is inhibited by ICI 200,355.
The American journal of physiology 1992;262(1 Pt 1):L86-91.
1992: P G Jorens; P D Graf; Iris F Ueki; J Olesch; Jay A Nadel
Interleukin-8 induces neutrophil accumulation in the trachea of allergic dogs.
Transactions of the Association of American Physicians 1992;105():190-6.
1991: Jay A Nadel; Douglas J Conrad; Iris F Ueki; A Schuster; E Sigal
Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocytes, leukocytes, and airway cells.
The Journal of clinical investigation 1991;87(4):1139-45.
1990: Jay A Nadel; Iris F Ueki; A Schuster; Douglas J Conrad; E Sigal
Arachidonate 15-lipoxygenase: immunocytochemical localization in blood and airway cells.
Transactions of the Association of American Physicians 1990;103():145-53.
1990: I Rubinstein; I Iwamoto; Iris F Ueki; D B Borson; Jay A Nadel
Recombinant neutral endopeptidase attenuates substance P-induced plasma extravasation in the guinea pig skin.
International archives of allergy and applied immunology 1990;91(3):232-8.
1989: Jonathan H Widdicombe; Iris F Ueki; D Emery; D Margolskee; J Yergey; Jay A Nadel
Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human.
The American journal of physiology 1989;257(6 Pt 1):L361-5.
1989: I Iwamoto; Iris F Ueki; D B Borson; Jay A Nadel
Neutral endopeptidase modulates tachykinin-induced increase in vascular permeability in guinea pig skin.
International archives of allergy and applied immunology 1989;88(3):288-93.
1988: I Iwamoto; Iris F Ueki; Jay A Nadel
Effect of neutral endopeptidase inhibitors on 3H-substance P binding in rat ileum.
Neuropeptides 1988;11(4):185-93.
1988: J Tamaoki; Iris F Ueki; Jonathan H Widdicombe; Jay A Nadel
Stimulation of Cl secretion by neurokinin A and neurokinin B in canine tracheal epithelium.
The American review of respiratory disease 1988;137(4):899-902.
1988: David B Jacoby; Iris F Ueki; Jonathan H Widdicombe; D A Loegering; G J Gleich; Jay A Nadel
Effect of human eosinophil major basic protein on ion transport in dog tracheal epithelium.
The American review of respiratory disease 1988;137(1):13-6.
1987: J Tamaoki; K Sekizawa; Iris F Ueki; P D Graf; J A Nadel; T D Bigby
Effect of macrophage stimulation on parasympathetic airway contraction in dogs.
European journal of pharmacology 1987;138(3):421-5.
1987: J Tamaoki; K Sekizawa; Molly L Osborne; Iris F Ueki; P D Graf; J A Nadel
Platelet aggregation increases cholinergic neurotransmission in canine airway.
Journal of applied physiology (Bethesda, Md. : 1985) 1987;62(6):2246-51.
1986: J Seltzer; B G Bigby; M Stulbarg; M J Holtzman; J A Nadel; Iris F Ueki; George Leikauf; E J Goetzl; Homer A Boushey
O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans.
Journal of applied physiology (Bethesda, Md. : 1985) 1986;60(4):1321-6.
1986: K F Chung; H Aizawa; George Leikauf; Iris F Ueki; T W Evans; J A Nadel
Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation.
The Journal of pharmacology and experimental therapeutics 1986;236(3):580-4.
1986: George Leikauf; Iris F Ueki; Jonathan H Widdicombe; J A Nadel
Alteration of chloride secretion across canine tracheal epithelium by lipoxygenase products of arachidonic acid.
The American journal of physiology 1986;250(1 Pt 2):F47-53.
1985: H Aizawa; K F Chung; George Leikauf; Iris F Ueki; R A Bethel; P M O'Byrne; T Hirose; J A Nadel
Significance of thromboxane generation in ozone-induced airway hyperresponsiveness in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1985;59(6):1918-23.
1985: P M O'Byrne; George Leikauf; H Aizawa; R A Bethel; Iris F Ueki; M J Holtzman; J A Nadel
Leukotriene B4 induces airway hyperresponsiveness in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1985;59(6):1941-6.
1985: George Leikauf; Iris F Ueki; J A Nadel; Jonathan H Widdicombe
Bradykinin stimulates Cl secretion and prostaglandin E2 release by canine tracheal epithelium.
The American journal of physiology 1985;248(1 Pt 2):F48-55.
1984: George Leikauf; Iris F Ueki; J A Nadel
Autonomic regulation of viscoelasticity of cat tracheal gland secretions.
Journal of applied physiology: respiratory, environmental and exercise physiology 1984;56(2):426-30.