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Simon Bouffler

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Mark P Little; Kotaro Ozasa; Soile Tapio; Andrew M Taylor; Ioanna Tzoulaki; Wendy L Vandoolaeghe; Richard Wakeford; Lydia B Zablotska; Wei Zhang; Tamara V Azizova; Dimitry Bazyka; Simon D Bouffler; Elisabeth Cardis; Sergey Yu Chekin; Vadim Chumak; Francis A Cucinotta; Florent de Vathaire; Per Hall; John D Harrison; Guido Hildebrandt; Victor Ivanov; Valeriy V Kashcheev; Sergiy V Klymenko; Olivier Laurent; Steven E Lipshultz
Comment on "dose-responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors" (Radiat. Environ. Biophys (2012) 51:165-178) by Schöllnberger et al.
Simon D Bouffler; Phil Gilvin; Elizabeth Ainsbury; John Harrison
Radiation-induced cataracts: the Health Protection Agency's response to the ICRP statement on tissue reactions and recommendation on the dose limit for the eye lens.
P Finnon; Sylwia Kabacik; Alan MacKay; Roger Owen; Claudine Raffy; John Yarnold; Roger A'Hern; Christophe Badie; Simon D Bouffler
Correlation of in vitro lymphocyte radiosensitivity and gene expression with late normal tissue reactions following curative radiotherapy for breast cancer.

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All Publications

2013: Mark P Little; Kotaro Ozasa; Soile Tapio; Andrew M Taylor; Ioanna Tzoulaki; Wendy L Vandoolaeghe; Richard Wakeford; Lydia B Zablotska; Wei Zhang; Tamara V Azizova; Dimitry Bazyka; Simon D Bouffler; Elisabeth Cardis; Sergey Yu Chekin; Vadim Chumak; Francis A Cucinotta; Florent de Vathaire; Per Hall; John D Harrison; Guido Hildebrandt; Victor Ivanov; Valeriy V Kashcheev; Sergiy V Klymenko; Olivier Laurent; Steven E Lipshultz
Comment on "dose-responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors" (Radiat. Environ. Biophys (2012) 51:165-178) by Schöllnberger et al.
Radiation and environmental biophysics 2013;52(1):157-9.
2012: Simon D Bouffler; Phil Gilvin; Elizabeth Ainsbury; John Harrison
Radiation-induced cataracts: the Health Protection Agency's response to the ICRP statement on tissue reactions and recommendation on the dose limit for the eye lens.
Journal of radiological protection : official journal of the Society for Radiological Protection 2012;32(4):479-88.
2012: P Finnon; Sylwia Kabacik; Alan MacKay; Roger Owen; Claudine Raffy; John Yarnold; Roger A'Hern; Christophe Badie; Simon D Bouffler
Correlation of in vitro lymphocyte radiosensitivity and gene expression with late normal tissue reactions following curative radiotherapy for breast cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012;105(3):329-36.
2012: Mark P Little; Kotaro Ozasa; Thierry Schneider; Soile Tapio; Andrew M Taylor; Ioanna Tzoulaki; Wendy L Vandoolaeghe; Richard Wakeford; Lydia B Zablotska; Wei Zhang; Tamara V Azizova; Dimitry Bazyka; Simon D Bouffler; Elisabeth Cardis; SIu Chekin; Vadim Chumak; Francis A Cucinotta; Florent de Vathaire; Per Hall; John D Harrison; Guido Hildebrandt; Victor Ivanov; Valeriy V Kashcheev; Sergiy V Klymenko; Michaela Kreuzer; Olivier Laurent; Steven E Lipshultz
Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks.
Environmental health perspectives 2012;120(11):1503-11.
2011: Michele Ellender; John D Harrison; Emmy Meijne; rene huiskamp; Ryszard E Kozlowski; Jackie W Haines; Alan A Edwards; Elizabeth A Ainsbury; John C Moody; Simon D Bouffler; Roger Cox
Intestinal tumours induced in Apc(Min/+) mice by X-rays and neutrons.
International journal of radiation biology 2011;87(4):385-99.
2011: N L Brown; R Finnon; R A Bulman; P Finnon; J Moody; Simon D Bouffler; C Badie
Sfpi1/PU.1 mutations in mouse radiation-induced acute myeloid leukaemias affect mRNA and protein abundance and associate with disrupted transcription.
Leukemia research 2011;35(1):126-32.
2010: Jackie W Haines; Margaret R Coster; Julie Adam; Michael Cheeseman; Elizabeth A Ainsbury; John Thacker; Simon D Bouffler
Xrcc2 modulates spontaneous and radiation-induced tumorigenesis in Apcmin/+ mice.
Molecular cancer research : MCR 2010;8(9):1227-33.
2009: Yuanlin Peng; Thomas B Borak; Simon D Bouffler; Robert L Ullrich; Michael M Weil; Joel S Bedford
Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma Rays. Part II. Theoretical considerations based on microdosimetry and the initial induction of chromosome aberrations.
Radiation research 2009;171(4):484-93.
2009: Yuanlin Peng; Natalie Brown; Rosemary Finnon; Christy L Warner; Xianan Liu; Paula C Genik; Matthew A Callan; F Andrew Ray; Thomas B Borak; Christophe Badie; Simon D Bouffler; Robert L Ullrich; Joel S Bedford; Michael M Weil
Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma rays. Part I. Experimental observations.
Radiation research 2009;171(4):474-83.
2009: Mark P Little; Richard Wakeford; E Janet Tawn; Simon D Bouffler; Amy Berrington de Gonzalez
Risks associated with low doses and low dose rates of ionizing radiation: why linearity may be (almost) the best we can do.
Radiology 2009;251(1):6-12.
2008: C Badie; S Dziwura; C Raffy; T Tsigani; G Alsbeih; John Moody; P Finnon; E Levine; D Scott; Simon D Bouffler
Aberrant CDKN1A transcriptional response associates with abnormal sensitivity to radiation treatment.
British journal of cancer 2008;98(11):1845-51.
2008: Paul Finnon; Naomi Robertson; Sylwia Dziwura; Claudine Raffy; Wei Zhang; Liz Ainsbury; Jaakko Kaprio; Christophe Badie; Simon D Bouffler
Evidence for significant heritability of apoptotic and cell cycle responses to ionising radiation.
Human genetics 2008;123(5):485-93.
2008: Toshiyasu Iwasaki; Naomi Robertson; Theodora Tsigani; P Finnon; David Scott; Ed Levine; Christophe Badie; Simon D Bouffler
Lymphocyte telomere length correlates with in vitro radiosensitivity in breast cancer cases but is not predictive of acute normal tissue reactions to radiotherapy.
International journal of radiation biology 2008;84(4):277-84.
2008: Simon D Bouffler; P Finnon; M A Blasco; E Ainsbury
A possible role for telomerase RNA and telomere length in global mitotic recombination.
Cytogenetic and genome research 2008;122(3-4):292-6.
2008: JE Moquet; E Ainsbury; Simon D Bouffler; David Lloyd
Exposure to low level GSM 935 MHZ radiofrequency fields does not induce apoptosis in proliferating or differentiated murine neuroblastoma cells.
Radiation protection dosimetry 2008;131(3):287-96.
2007: Andrew Sims; P Finnon; C J Miller; Simon D Bouffler; Anthony Howell; D Scott; Robert B Clarke
TPD52 and NFKB1 gene expression levels correlate with G2 chromosomal radiosensitivity in lymphocytes of women with and at risk of hereditary breast cancer.
International journal of radiation biology 2007;83(6):409-20.
2007: Simon D Bouffler; Richard D Saunders
Plenary discussion--Experimental studies sessions I and II.
Progress in biophysics and molecular biology 2007;93(1-3):411-3.
2006: C I Kowalczuk; M C Priestner; A J Pearson; Richard D Saunders; Simon D Bouffler
Wavelength dependence of cellular responses in human melanocytes and melanoma cells following exposure to ultraviolet radiation.
International journal of radiation biology 2006;82(11):781-92.
2006: B F Wall; Gerry M Kendall; Alan A Edwards; Simon D Bouffler; Colin R Muirhead; J R Meara
What are the risks from medical X-rays and other low dose radiation?
The British journal of radiology 2006;79(940):285-94.
2006: Michele Ellender; John D Harrison; R Kozlowski; M Szłuińska; Simon D Bouffler; Roger Cox
In utero and neonatal sensitivity of ApcMin/+ mice to radiation-induced intestinal neoplasia.
International journal of radiation biology 2006;82(3):141-51.
2006: Robert A Bulman; Tommaso A Dragani; Simon D Bouffler; Roger Cox
Locations of mouse DNA damage response and repair loci, and cancer risk modifiers.
DNA repair 2006;5(2):274-7.
2006: F Darakhshan; C Badie; John Moody; Margaret Coster; Rosemary Finnon; P Finnon; Alan A Edwards; Marta Szluinska; C J Skidmore; K Yoshida; R Ullrich; Roger Cox; Simon D Bouffler
Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.
Carcinogenesis 2006;27(2):311-8.
2005: Michele Ellender; John D Harrison; Alan A Edwards; Simon D Bouffler; Roger Cox
Direct single gene mutational events account for radiation-induced intestinal adenoma yields in Apc(Min/+) mice.
Radiation research 2005;163(5):552-6.
2002: Simon D Bouffler; Andrew Silver; Roger Cox
Mechanistic and genetic studies of radiation tumorigenesis in the mouse--implications for low dose risk estimation.
Journal of radiological protection : official journal of the Society for Radiological Protection 2002;22(3A):A11-6.
2002: Silvia Espejel; Sonia Franco; Sandra Rodríguez-Perales; Simon D Bouffler; Juan C Cigudosa; María A Blasco
Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.
The EMBO journal 2002;21(9):2207-19.
2001: P Finnon; Hiu-Pak Wong; A R Silver; Predrag Slijepcevic; Simon D Bouffler
Long but dysfunctional telomeres correlate with chromosomal radiosensitivity in a mouse AML cell line.
International journal of radiation biology 2001;77(12):1151-62.
2001: Simon D Bouffler; M A Blasco; Roger Cox; P J Smith
Telomeric sequences, radiation sensitivity and genomic instability.
International journal of radiation biology 2001;77(10):995-1005.
2001: Emmy Meijne; rene huiskamp; Jackie Haines; John Moody; Rosemary Finnon; Jennifer Wilding; S Spanjer; Simon D Bouffler; Alan Edwards; Roger Cox; Andrew Silver
Analysis of loss of heterozygosity in lymphoma and leukaemia arising in F1 hybrid mice locates a common region of chromosome 4 loss.
Genes, chromosomes & cancer 2001;31(4):373-81.
2001: R Kozlowski; Simon D Bouffler; JW Haines; John D Harrison; Roger Cox
In utero haemopoietic sensitivity to alpha, beta or X-irradiation in CBA/H mice.
International journal of radiation biology 2001;77(7):805-15.
2001: J McIlrath; Simon D Bouffler; Enrique Samper; A Cuthbert; Andrzej Wojcik; Irena Szumiel; Peter E Bryant; Andrew C Riches; A Thompson; María A Blasco; R F Newbold; Predrag Slijepcevic
Telomere length abnormalities in mammalian radiosensitive cells.
Cancer research 2001;61(3):912-5.
2001: Simon D Bouffler; JW Haines; Alan A Edwards; John D Harrison; Roger Cox
Lack of detectable transmissible chromosomal instability after in vivo or in vitro exposure of mouse bone marrow cells to 224Ra alpha particles.
Radiation research 2001;155(2):345-52.
2000: Fermín A Goytisolo; Enrique Samper; Juan Martín-Caballero; P Finnon; Eloisa Herrera; Juana M Flores; Simon D Bouffler; María A Blasco
Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals.
The Journal of experimental medicine 2000;192(11):1625-36.
2000: Simon D Bouffler; N Hofland; Roger Cox; Riccardo Fodde
Evidence for Msh2 haploinsufficiency in mice revealed by MNU-induced sister-chromatid exchange analysis.
British journal of cancer 2000;83(10):1291-4.
2000: P Finnon; A R Silver; Simon D Bouffler
Upregulation of telomerase activity by X-irradiation in mouse leukaemia cells is independent of Tert, Terc, Tnks and Myc transcription.
Carcinogenesis 2000;21(4):573-8.
2000: Simonetta Pazzaglia; L Pariset; Simonetta Rebessi; Anna Saran; M Coppola; Vincenzo Covelli; John Moody; Simon D Bouffler; Roger Cox; Andrew Silver
Somatic cell hybrids for high-density mapping of chromosome 2 breakpoints in radiation-induced myeloid leukemia cell lines from inbred mice.
Molecular carcinogenesis 2000;27(3):219-28.
1999: M Prakash Hande; Predrag Slijepcevic; Andrew Silver; Simon D Bouffler; P van Buul; P Bryant; P Lansdorp
Elongated telomeres in scid mice.
Genomics 1999;56(2):221-3.
1999: Andrew Silver; John Moody; R Dunford; D Clark; S Ganz; R Bulman; Simon D Bouffler; P Finnon; Emmy Meijne; rene huiskamp; Roger Cox
Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12.
Genes, chromosomes & cancer 1999;24(2):95-104.
1998: Simon D Bouffler
Involvement of telomeric sequences in chromosomal aberrations.
Mutation research 1998;404(1-2):199-204.
1997: Predrag Slijepcevic; M Prakash Hande; Simon D Bouffler; P Lansdorp; Peter E Bryant
Telomere length, chromatin structure and chromosome fusigenic potential.
Chromosoma 1997;106(7):413-21.
1997: Simon D Bouffler; E I Meijne; D J Morris; D Papworth
Chromosome 2 hypersensitivity and clonal development in murine radiation acute myeloid leukaemia.
International journal of radiation biology 1997;72(2):181-9.
1996: Simon D Bouffler; William F Morgan; T K Pandita; Predrag Slijepcevic
The involvement of telomeric sequences in chromosomal aberrations.
Mutation research 1996;366(2):129-35.
1996: Simon D Bouffler; E I Meijne; rene huiskamp; R Cox
Chromosomal abnormalities in neutron-induced acute myeloid leukemias in CBA/H mice.
Radiation research 1996;146(3):349-52.
1996: D J Clark; E I Meijne; Simon D Bouffler; rene huiskamp; C J Skidmore; R Cox; A R Silver
Microsatellite analysis of recurrent chromosome 2 deletions in acute myeloid leukaemia induced by radiation in F1 hybrid mice.
Genes, chromosomes & cancer 1996;16(4):238-46.
1996: E I Meijne; A R Silver; Simon D Bouffler; D J Morris; E W van Kampen; S Spanjer; rene huiskamp; R Cox
Role of telomeric sequences in murine radiation-induced myeloid leukaemia.
Genes, chromosomes & cancer 1996;16(4):230-7.
1996: Simon D Bouffler; G Breckon; R Cox
Chromosomal mechanisms in murine radiation acute myeloid leukaemogenesis.
Carcinogenesis 1996;17(4):655-9.
1995: Simon D Bouffler; Christopher J Kemp; Allan Balmain; R Cox
Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice.
Cancer research 1995;55(17):3883-9.
1993: Simon D Bouffler; Andrew Silver; R Cox
The role of DNA repeats and associated secondary structures in genomic instability and neoplasia.
BioEssays : news and reviews in molecular, cellular and developmental biology 1993;15(6):409-12.
1993: Simon D Bouffler; Andrew Silver; D Papworth; J Coates; R Cox
Murine radiation myeloid leukaemogenesis: relationship between interstitial telomere-like sequences and chromosome 2 fragile sites.
Genes, chromosomes & cancer 1993;6(2):98-106.