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Helle Ulrich

Research Profile

Chemicals & Drugs

Living Beings

Saccharomyces cerevisiae

Disorders

DNA Damage

Physiology

Phenomena

Ubiquitination

Concepts & Ideas

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Publications

TOP 3
Joanne L Parker; Helle D Ulrich
A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA.
Daniel Finley; Thomas Sommer; Helle D Ulrich; Peter Kaiser
The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Helle D Ulrich
Ubiquitin, SUMO, and phosphate: how a trio of posttranslational modifiers governs protein fate.

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All Publications

2012: Joanne L Parker; Helle D Ulrich
A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA.
Nucleic acids research 2012;40(22):11380-8.
2012: Daniel Finley; Thomas Sommer; Helle D Ulrich; Peter Kaiser
The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Genetics 2012;192(2):319-60.
2012: Helle D Ulrich
Ubiquitin, SUMO, and phosphate: how a trio of posttranslational modifiers governs protein fate.
Molecular cell 2012;47(3):335-7.
2012: Helle D Ulrich
Ubiquitin and SUMO in DNA repair at a glance.
Journal of cell science 2012;125(Pt 2):249-54.
2012: Joanne L Parker; Helle D Ulrich
In vitro PCNA modification assays.
Methods in molecular biology (Clifton, N.J.) 2012;920():569-89.
2012: Adelina A Davies; Helle D Ulrich
Detection of PCNA modifications in Saccharomyces cerevisiae.
Methods in molecular biology (Clifton, N.J.) 2012;920():543-67.
2011: Stefan Brückner; Sandra Kern; Irene Saugar; Helle D Ulrich; Raphael Birke; Hans-Ulrich Mösch
The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development.
Genetics 2011;189(2):479-94.
2011: Helle D Ulrich
Timing and spacing of ubiquitin-dependent DNA damage bypass.
FEBS letters 2011;585(18):2861-7.
2010: Helle D Ulrich; Helen Walden
Ubiquitin signalling in DNA replication and repair.
Nature reviews. Molecular cell biology 2010;11(7):479-89.
2010: yasukazu Daigaku; Adelina A Davies; Helle D Ulrich
Ubiquitin-dependent DNA damage bypass is separable from genome replication.
Nature 2010;465(7300):951-5.
2010: Adelina A Davies; Andrea Neiss; Helle D Ulrich
Ubiquitylation of the 9-1-1 checkpoint clamp is independent of rad6-rad18 and DNA damage.
Cell 2010;141(6):1080-7.
2010: Shengkai Zhao; Helle D Ulrich
Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(17):7704-9.
2009: Joanne L Parker; Helle D Ulrich
Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5.
The EMBO journal 2009;28(23):3657-66.
2009: Patricia Auffret van der Kemp; Marcelo de Padula; Guenaelle Burguiere-Slezak; Helle D Ulrich; Serge Boiteux
PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae.
Nucleic acids research 2009;37(8):2549-59.
2009: Helle D Ulrich
Preface. Ubiquitin, SUMO and the maintenance of genome stability.
DNA repair 2009;8(4):429.
2009: Helle D Ulrich
Regulating post-translational modifications of the eukaryotic replication clamp PCNA.
DNA repair 2009;8(4):461-9.
2009: Helle D Ulrich
SUMO Protocols. Preface.
Methods in molecular biology (Clifton, N.J.) 2009;497():v-vi.
2008: Helle D Ulrich
The fast-growing business of SUMO chains.
Molecular cell 2008;32(3):301-5.
2008: Joanne L Parker; Andrea Bucceri; Adelina A Davies; Katharina Heidrich; Hanna Windecker; Helle D Ulrich
SUMO modification of PCNA is controlled by DNA.
The EMBO journal 2008;27(18):2422-31.
2008: Adelina A Davies; Diana Huttner; yasukazu Daigaku; Shuhua Chen; Helle D Ulrich
Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a.
Molecular cell 2008;29(5):625-36.
2008: Hanna Windecker; Helle D Ulrich
Architecture and assembly of poly-SUMO chains on PCNA in Saccharomyces cerevisiae.
Journal of molecular biology 2008;376(1):221-31.
2007: Helle D Ulrich
SUMO teams up with ubiquitin to manage hypoxia.
Cell 2007;131(3):446-7.
2007: Joanne L Parker; Aleksandra B Bielen; Ivan Dikic; Helle D Ulrich
Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase eta in Saccharomyces cerevisiae.
Nucleic acids research 2007;35(3):881-9.
2006: Caixia Guo; Tie-Shan Tang; Marzena Bienko; Joanne L Parker; Aleksandra B Bielen; Eiichiro Sonoda; Shunichi Takeda; Helle D Ulrich; Ivan Dikic; Errol C Friedberg
Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage.
Molecular and cellular biology 2006;26(23):8892-900.
2006: Caixia Guo; Eiichiro Sonoda; Tie-Shan Tang; Joanne L Parker; Aleksandra B Bielen; Shunichi Takeda; Helle D Ulrich; Errol C Friedberg
REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo.
Molecular cell 2006;23(2):265-71.
2006: Jonathan Frampton; Anja Irmisch; Catherine Green; Andrea Neiss; Michelle Trickey; Helle D Ulrich; Kanji Furuya; Felicity Z Watts; Antony M Carr; Alan Lehmann
Postreplication repair and PCNA modification in Schizosaccharomyces pombe.
Molecular biology of the cell 2006;17(7):2976-85.
2006: Helle D Ulrich
Deubiquitinating PCNA: a downside to DNA damage tolerance.
Nature cell biology 2006;8(4):303-5.
2006: Sovan Sarkar; Adelina A Davies; Helle D Ulrich; Peter J McHugh
DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta.
The EMBO journal 2006;25(6):1285-94.
2005: Helle D Ulrich; Sabina Vogel; Adelina A Davies
SUMO keeps a check on recombination during DNA replication.
Cell cycle (Georgetown, Tex.) 2005;4(12):1699-702.
2005: Helle D Ulrich
The RAD6 pathway: control of DNA damage bypass and mutagenesis by ubiquitin and SUMO.
Chembiochem : a European journal of chemical biology 2005;6(10):1735-43.
2005: Helle D Ulrich
Mutual interactions between the SUMO and ubiquitin systems: a plea of no contest.
Trends in cell biology 2005;15(10):525-32.
2005: Efterpi Papouli; Shuhua Chen; Adelina A Davies; Diana Huttner; Lumir Krejci; Patrick Sung; Helle D Ulrich
Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p.
Molecular cell 2005;19(1):123-33.
2005: Helle D Ulrich
SUMO modification: wrestling with protein conformation.
Current biology : CB 2005;15(7):R257-9.
2005: Shuhua Chen; Adelina A Davies; Daniel Sagan; Helle D Ulrich
The RING finger ATPase Rad5p of Saccharomyces cerevisiae contributes to DNA double-strand break repair in a ubiquitin-independent manner.
Nucleic acids research 2005;33(18):5878-86.
2004: Amandine Bugnicourt; Marine Froissard; Kostianna Sereti; Helle D Ulrich; Rosine Haguenauer-Tsapis; Jean-Marc Galan
Antagonistic roles of ESCRT and Vps class C/HOPS complexes in the recycling of yeast membrane proteins.
Molecular biology of the cell 2004;15(9):4203-14.
2004: K Anke Schürer; Christian Rudolph; Helle D Ulrich; Wilfried Kramer
Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair.
Genetics 2004;166(4):1673-86.
2004: Helle D Ulrich
How to activate a damage-tolerant polymerase: consequences of PCNA modifications by ubiquitin and SUMO.
Cell cycle (Georgetown, Tex.) 2004;3(1):15-8.
2003: Philipp Stelter; Helle D Ulrich
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation.
Nature 2003;425(6954):188-91.
2003: Helle D Ulrich
Protein-protein interactions within an E2-RING finger complex. Implications for ubiquitin-dependent DNA damage repair.
The Journal of biological chemistry 2003;278(9):7051-8.
2002: Helle D Ulrich
Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatin.
Eukaryotic cell 2002;1(1):1-10.
2002: Helle D Ulrich
Natural substrates of the proteasome and their recognition by the ubiquitin system.
Current topics in microbiology and immunology 2002;268():137-74.
2001: Helle D Ulrich
The srs2 suppressor of UV sensitivity acts specifically on the RAD5- and MMS2-dependent branch of the RAD6 pathway.
Nucleic acids research 2001;29(17):3487-94.