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Christopher Umbricht

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Matthew T Olson; Christopher B Umbricht; Syed Z Ali; Patricia Aragon Han; Thiraphon Boonyaarunnate; Martha A Zeiger
A tertiary center's experience with second review of 3885 thyroid cytopathology specimens.
Yan Liu; Nijaguna B Prasad; Lauren Sangenario; Helina Somervell; Wenyue Sun; Kristen Talbot; Justin Bishop; Joseph A Califano; Leslie Cope; Yongchun Wang; William H Westra; Martha A Zeiger; Christopher B Umbricht
DNA copy number variations characterize benign and malignant thyroid tumors.
Kathleen C Lee; Carol Li; Eric Bergeim Schneider; Helina Somervell; Christopher B Umbricht; Yongchun Wang; Matthew Krafft; Martha A Zeiger
Is BRAF mutation associated with lymph node metastasis in patients with papillary thyroid cancer?

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All Publications

2013: Matthew T Olson; Christopher B Umbricht; Syed Z Ali; Patricia Aragon Han; Thiraphon Boonyaarunnate; Martha A Zeiger
A tertiary center's experience with second review of 3885 thyroid cytopathology specimens.
The Journal of clinical endocrinology and metabolism 2013;98(4):1450-7.
2013: Yan Liu; Nijaguna B Prasad; Lauren Sangenario; Helina Somervell; Wenyue Sun; Kristen Talbot; Justin Bishop; Joseph A Califano; Leslie Cope; Yongchun Wang; William H Westra; Martha A Zeiger; Christopher B Umbricht
DNA copy number variations characterize benign and malignant thyroid tumors.
The Journal of clinical endocrinology and metabolism 2013;98(3):E558-66.
2012: Kathleen C Lee; Carol Li; Eric Bergeim Schneider; Helina Somervell; Christopher B Umbricht; Yongchun Wang; Matthew Krafft; Martha A Zeiger
Is BRAF mutation associated with lymph node metastasis in patients with papillary thyroid cancer?
Surgery 2012;152(6):977-83.
2012: Mariana Brait; Steven Goodman; Myriam Loyo; Alina Markova; Kimberly Laskie Ostrow; Silvana Papagerakis; Eli Rosenbaum; David Sidransky; Christopher B Umbricht; Marianna Zahurak; Martha A Zeiger; Mohammad Hoque
Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer.
Epigenetics : official journal of the DNA Methylation Society 2012;7(7):710-9.
2012: Nijaguna B Prasad; Helina Somervell; Kristin Talbot; Hua-Ling Tsai; Christopher B Umbricht; Yongchun Wang; William H Westra; Douglas P Clark; Alan P B Dackiw; Guennadi Kouniavsky; Jeanne Kowalski; Steven Libutti; Martha A Zeiger
Three-gene molecular diagnostic model for thyroid cancer.
Thyroid : official journal of the American Thyroid Association 2012;22(3):275-84.
2011: Nephtali Ruiz Gomez; Guennadi Kouniavsky; Jeanne Kowalski; Sara I Pai; Helina Somervell; Hua-Ling Tsai; Ralph P Tufano; Christopher B Umbricht; Alan P B Dackiw; Martha A Zeiger
Tumor size and presence of calcifications on ultrasonography are pre-operative predictors of lymph node metastases in patients with papillary thyroid cancer.
Journal of surgical oncology 2011;104(6):613-6.
2011: Mary Jo Fackler; Joe W Gray; Peng Huang; Jeffrey Marks; Vanessa F Merino; Pedram Argani; Leslie Cope; Leigh-Ann Cruz; Stephen Ethier; Wei Wen Teo; Christopher B Umbricht; Kala Visvanathan; Danielle Williams; Antonio C Wolff; Zhe Zhang; Saraswati Sukumar
Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence.
Cancer research 2011;71(19):6195-207.
2011: Yongchun Wang; William H Westra; Martha A Zeiger; Christopher Heaphy; Jeanne Kowalski; Alan K Meeker; Nijaguna B Prasad; Lauren E Sangenario; Helina Somervell; Hua-Ling Tsai; Christopher B Umbricht
Telomere length is related to alternative splice patterns of telomerase in thyroid tumors.
The American journal of pathology 2011;179(3):1415-24.
2011: Tiffany Hung; Manolis Kellis; Seung K Kim; Ashley K Koegel; Benjamin Kong; Yojiro Kotake; Anita Langerød; Michael F Lin; Nilay Shah; Saraswati Sukumar; Christopher B Umbricht; Marc van de Vijver; Pei Wang; Yu Wang; Yulei Wang; Michael L Whitfield; David J Wong; Yue Xiong; Anne-Lise Børresen-Dale; Gavin D Grant; Hugo M Horlings; Howard Y Chang
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.
Nature genetics 2011;43(7):621-9.
2011: Radharani Marik; Madhan Allu; RAVI ANCHOORI; Vered Stearns; Christopher B Umbricht; Saeed R Khan
Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer.
Cancer biology & therapy 2011;11(10):883-92.
2011: Vladimir K Neychev; Guennadi Kouniavsky; Zita Shiue; Don N Udall; Helina Somervell; Christopher B Umbricht; Martha A Zeiger
Chasing "shadows": discovering the subtleties of sestamibi scans to facilitate minimally invasive parathyroidectomy.
World journal of surgery 2011;35(1):140-6.
2010: Catherine E Pesce; Zita Shiue; Hua-Ling Tsai; Christopher B Umbricht; Ralph P Tufano; Alan P B Dackiw; Jeanne Kowalski; Martha A Zeiger
Postoperative hypocalcemia after thyroidectomy for Graves' disease.
Thyroid : official journal of the American Thyroid Association 2010;20(11):1279-83.
2010: Radharani Marik; Mary Jo Fackler; Edward Gabrielson; Martha A Zeiger; Saraswati Sukumar; Vered Stearns; Christopher B Umbricht
DNA methylation-related vitamin D receptor insensitivity in breast cancer.
Cancer biology & therapy 2010;10(1):44-53.
2008: SHANE MORITA; Helina Somervell; Christopher B Umbricht; Alan P B Dackiw; Martha A Zeiger
Evaluation for concomitant thyroid nodules and primary hyperparathyroidism in patients undergoing parathyroidectomy or thyroidectomy.
Surgery 2008;144(6):862-6; discussion 866-8.
2008: Yongchun Wang; Jeanne Kowalski; Hua-Ling Tsai; Radharani Marik; Nijaguna B Prasad; Helina Somervell; Pang-Kuo Lo; Lauren E Sangenario; Lars Dyrskjot; Torben F Orntoft; William H Westra; Alan K Meeker; James R Eshleman; Christopher B Umbricht; Martha A Zeiger
Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms.
Thyroid : official journal of the American Thyroid Association 2008;18(10):1055-63.
2008: Nia D Banks; Jeanne Kowalski; Hua-Ling Tsai; Helina Somervell; Ralph P Tufano; Alan P B Dackiw; Michael Marohn; Douglas P Clark; Christopher B Umbricht; Martha A Zeiger
A diagnostic predictor model for indeterminate or suspicious thyroid FNA samples.
Thyroid : official journal of the American Thyroid Association 2008;18(9):933-41.
2008: Nijaguna B Prasad; Helina Somervell; Ralph P Tufano; Alan P B Dackiw; Michael Marohn; Joseph A Califano; Yongchun Wang; William H Westra; Douglas P Clark; Christopher B Umbricht; Steven Libutti; Martha A Zeiger
Identification of genes differentially expressed in benign versus malignant thyroid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3327-37.
2006: Shuiying Hu; Dingxie Liu; Ralph P Tufano; Kathryn Carson; Eli Rosenbaum; Yoram Cohen; Elizabeth H Holt; Katja Kiseljak-Vassiliades; Kerry J Rhoden; Sara Tolaney; Stephen Condouris; Giovanni Tallini; William H Westra; Christopher B Umbricht; Martha A Zeiger; Joseph A Califano; Vasily Vasko; Michael M. Xing
Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.
International journal of cancer. Journal international du cancer 2006;119(10):2322-9.
2005: Jennifer Rosen; Mei He; Christopher B Umbricht; H Richard Alexander; Alan P B Dackiw; Martha A Zeiger; Steven Libutti
A six-gene model for differentiating benign from malignant thyroid tumors on the basis of gene expression.
Surgery 2005;138(6):1050-6; discussion 1056-7.
2005: Michael M. Xing; William H Westra; Ralph P Tufano; Yoram Cohen; Eli Rosenbaum; Kerry J Rhoden; Kathryn Carson; Vasily Vasko; Alexandr Larin; Giovanni Tallini; Sara Tolaney; Elizabeth H Holt; Pei Hui; Christopher B Umbricht; Shehzad Basaria; Marge Ewertz; Anthony P Tufaro; Joseph A Califano; Matthew D Ringel; Martha A Zeiger; David Sidransky; Paul W Ladenson
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism 2005;90(12):6373-9.
2005: Mohammad Hoque; Eli Rosenbaum; William H Westra; Michael M. Xing; Paul W Ladenson; Martha A Zeiger; David Sidransky; Christopher B Umbricht
Quantitative assessment of promoter methylation profiles in thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 2005;90(7):4011-8.
2005: Susanne Diehl; Christopher B Umbricht; Alan P B Dackiw; Martha A Zeiger
Modern approaches to age-old questions about thyroid tumors.
Thyroid : official journal of the American Thyroid Association 2005;15(6):575-82.
2004: Christopher B Umbricht; George T Conrad; Douglas P Clark; William H Westra; Dañelle C Smith; Marianna Zahurak; Motoyasu Saji; Robert C Smallridge; Steven Goodman; Martha A Zeiger
Human telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5762-8.
2004: Yoram Cohen; Eli Rosenbaum; Douglas P Clark; Martha A Zeiger; Christopher B Umbricht; Ralph P Tufano; David Sidransky; William H Westra
Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2761-5.
2004: Chiara Mazzanti; Martha A Zeiger; Nick G Costouros; Christopher B Umbricht; William H Westra; Danelle Smith; Helina Somervell; Generoso Bevilacqua; H Richard Alexander; Steven Libutti; Nick Costourous
Using gene expression profiling to differentiate benign versus malignant thyroid tumors.
Cancer research 2004;64(8):2898-903.
2003: Dorry L Segev; Douglas P Clark; Martha A Zeiger; Christopher B Umbricht
Beyond the suspicious thyroid fine needle aspirate. A review.
Acta cytologica 2003;47(5):709-22.
2003: Dorry L Segev; Christopher B Umbricht; Martha A Zeiger
Molecular pathogenesis of thyroid cancer.
Surgical oncology 2003;12(2):69-90.
2001: Christopher B Umbricht; Ella Evron; Edward Gabrielson; A Ferguson; J Marks; Saraswati Sukumar
Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer.
Oncogene 2001;20(26):3348-53.
2001: Ella Evron; William C Dooley; Christopher B Umbricht; Dorothy L Rosenthal; N Sacchi; Edward Gabrielson; A B Soito; David T Hung; B Ljung; Nancy E Davidson; Saraswati Sukumar
Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR.
Lancet 2001;357(9265):1335-6.
2001: Ella Evron; Christopher B Umbricht; Dorian Korz; Venu Raman; David M Loeb; B Niranjan; Lakjaya Buluwela; Sigmund A Weitzman; J Marks; Saraswati Sukumar
Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation.
Cancer research 2001;61(6):2782-7.
2000: AT Ferguson; Ella Evron; Christopher B Umbricht; Tej K Pandita; Timothy Chan; H Hermeking; Jeffrey R Marks; AR Lambers; P Andrew Futreal; M R Stampfer; Saraswati Sukumar
High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6049-54.
1999: Lisa A Carey; Nam W Kim; Steven Goodman; J Marks; G Henderson; Christopher B Umbricht; Jeffrey S Dome; William C Dooley; S R Amshey; Saraswati Sukumar
Telomerase activity and prognosis in primary breast cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(10):3075-81.
1999: Jeffrey S Dome; S Chung; TL Bergemann; Christopher B Umbricht; Motoyasu Saji; Lisa A Carey; Paul E Grundy; Elizabeth J. Perlman; Norman E Breslow; Saraswati Sukumar
High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor.
Cancer research 1999;59(17):4301-7.
1999: Christopher B Umbricht; M E Sherman; Jeffrey S Dome; Lisa A Carey; J Marks; Nam W Kim; Saraswati Sukumar
Telomerase activity in ductal carcinoma in situ and invasive breast cancer.
Oncogene 1999;18(22):3407-14.
1999: Motoyasu Saji; S Xydas; William H Westra; C K Liang; Douglas P Clark; Robert Udelsman; Christopher B Umbricht; Saraswati Sukumar; Martha A Zeiger
Human telomerase reverse transcriptase (hTERT) gene expression in thyroid neoplasms.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(6):1483-9.
1999: SG Sawant; V Gregoire; S Dhar; Christopher B Umbricht; S Cvilic; Saraswati Sukumar; Tej K Pandita
Telomerase activity as a measure for monitoring radiocurability of tumor cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(9):1047-54.
1999: KE McKenzie; Christopher B Umbricht; Saraswati Sukumar
Applications of telomerase research in the fight against cancer.
Molecular medicine today 1999;5(3):114-22.
1998: Lubomir B Smilenov; W Mellado; Pulivarthi H Rao; SG Sawant; Christopher B Umbricht; Saraswati Sukumar; Tej K Pandita
Molecular cloning and chromosomal localization of Chinese hamster telomeric protein chTRF1. Its potential role in chromosomal instability.
Oncogene 1998;17(16):2137-42.
1998: Lisa A Carey; C A Hedican; G S Henderson; Christopher B Umbricht; Jeffrey S Dome; D Varon; Saraswati Sukumar
Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):435-40.
1997: D Varon; C Jiang; C Hedican; Jeffrey S Dome; Christopher B Umbricht; Lisa A Carey; H J Thompson; Saraswati Sukumar
Telomerase activity in the normal and neoplastic rat mammary gland.
Cancer research 1997;57(24):5605-9.
1997: Motoyasu Saji; William H Westra; Herbert Chen; Christopher B Umbricht; R M Tuttle; M F Box; Robert Udelsman; Saraswati Sukumar; Martha A Zeiger
Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid.
Surgery 1997;122(6):1137-40.
1997: Christopher B Umbricht; Motoyasu Saji; William H Westra; Robert Udelsman; Martha A Zeiger; Saraswati Sukumar
Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma.
Cancer research 1997;57(11):2144-7.
1994: L A Henricksen; Christopher B Umbricht; Marc S Wold
Recombinant replication protein A: expression, complex formation, and functional characterization.
The Journal of biological chemistry 1994;269(15):11121-32.
1994: Christopher B Umbricht; Constance A Griffin; Anita L Hawkins; K H Grzeschik; P O'Connell; Robin J Leach; Eric Green; Thomas J Kelly
High-resolution genomic mapping of the three human replication protein A genes (RPA1, RPA2, and RPA3).
Genomics 1994;20(2):249-57.
1993: Christopher B Umbricht; L F Erdile; Ethylin Jabs; Thomas J Kelly
Cloning, overexpression, and genomic mapping of the 14-kDa subunit of human replication protein A.
The Journal of biological chemistry 1993;268(9):6131-8.
1991: L F Erdile; Kathleen L Collins; A Russo; P Simancek; D Small; Christopher B Umbricht; D Virshup; L Cheng; S Randall; D Weinberg
Initiation of SV40 DNA replication: mechanism and control.
Cold Spring Harbor symposia on quantitative biology 1991;56():303-13.
1989: Christopher B Umbricht; Martin Oberholzer; R Gschwind; H Christen; Joachim Torhorst
Prognostic significance (relapse, non-relapse) of nuclear shape parameters in lymph node negative breast cancer.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1989;1(1):11-23.
1986: R Gschwind; Christopher B Umbricht; Joachim Torhorst; Martin Oberholzer
Evaluation of shape descriptors for the morphometric analysis of cell nuclei.
Pathology, research and practice 1986;181(2):213-22.
1982: D A Diamond; S J Berry; Christopher B Umbricht; H J Jewett; Donald S Coffey
Computerized image analysis of nuclear shape as a prognostic factor for prostatic cancer.
The Prostate 1982;3(4):321-32.