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Toshihiro Unno

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Hayato Matsuyama; Yasuyuki Tanahashi; Takio Kitazawa; Seiichi Komori; Masahisa Yamada; Toshihiro Unno
Evidence for M2 and M3 muscarinic receptor involvement in cholinergic excitatory junction potentials through synergistic activation of cation channels in the longitudinal muscle of mouse ileum.
Hayato Matsuyama; Toshihiro Unno; Seiichi Komori; Tadashi Takewaki
Nitrergic inhibition of tachykininergic neuro-muscular transmission via cyclic GMP in the hamster ileum.
Ryu Fujikawa; Yoshikage Muroi; Toshihiro Unno; Toshiaki Ishii
Ouabain exacerbates botulinum neurotoxin-induced muscle paralysis via progression of muscle atrophy in mice.

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All Publications

2013: Hayato Matsuyama; Yasuyuki Tanahashi; Takio Kitazawa; Seiichi Komori; Masahisa Yamada; Toshihiro Unno
Evidence for M2 and M3 muscarinic receptor involvement in cholinergic excitatory junction potentials through synergistic activation of cation channels in the longitudinal muscle of mouse ileum.
Journal of pharmacological sciences 2013;121(3):227-36.
2011: Hayato Matsuyama; Toshihiro Unno; Seiichi Komori; Tadashi Takewaki
Nitrergic inhibition of tachykininergic neuro-muscular transmission via cyclic GMP in the hamster ileum.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2011;73(4):453-8.
2010: Ryu Fujikawa; Yoshikage Muroi; Toshihiro Unno; Toshiaki Ishii
Ouabain exacerbates botulinum neurotoxin-induced muscle paralysis via progression of muscle atrophy in mice.
The Journal of toxicological sciences 2010;35(6):795-805.
2010: Mayuko Suguro; Hayato Matsuyama; Yasuyuki Tanahashi; Toshihiro Unno; Takio Kitazawa; Masahisa Yamada; Seiichi Komori
Muscarinic receptor subtypes mediating Ca2+ sensitization of intestinal smooth muscle contraction: studies with receptor knockout mice.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2010;72(4):443-51.
2009: Takio Kitazawa; Koichi Asakawa; Tatsuro Nakamura; H Teraoka; Toshihiro Unno; Sei-Ichi Komori; Masahisa Yamada; Jürgen Wess
M3 muscarinic receptors mediate positive inotropic responses in mouse atria: a study with muscarinic receptor knockout mice.
The Journal of pharmacology and experimental therapeutics 2009;330(2):487-93.
2009: Toshihiro Unno; Hayato Matsuyama; Masashi Okawa; Muhammad Mubarak Hossain; Ryoko Iida; Haruo Kobayashi; Seiichi Komori
Tributyltin-induced Ca(2+) mobilization via L-type voltage-dependent Ca(2+) channels in PC12 cells.
Environmental toxicology and pharmacology 2009;28(1):70-7.
2008: Takashi Sakamoto; Hayato Matsuyama; Masayuki Yamamoto; Yasuyuki Tanahashi; Takio Kitazawa; Tetsuro Taneike; Seiichi Komori; Toshihiro Unno
A non-selective cationic channel activated by diacylglycerol in mouse intestinal myocytes.
European journal of pharmacology 2008;599(1-3):54-7.
2008: Masayuki Yamamoto; Toshihiro Unno; Hayato Matsuyama; Masanobu Kohda; Noriyuki Masuda; Masakazu Nishimura; Toshiaki Ishii; Seiichi Komori
Two types of cation channel activated by stimulation of muscarinic receptors in guinea-pig urinary bladder smooth muscle.
Journal of pharmacological sciences 2008;108(3):248-57.
2008: Takio Kitazawa; Ryuichi Hirama; Kozue Masunaga; Tatsuro Nakamura; Koichi Asakawa; Jinshan Cao; H Teraoka; Toshihiro Unno; Sei-ichi Komori; Masahisa Yamada; Jürgen Wess; Tetsuro Taneike
Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle.
Naunyn-Schmiedeberg's archives of pharmacology 2008;377(4-6):503-13.
2007: Takashi Sakamoto; Toshihiro Unno; Takio Kitazawa; Tetsuro Taneike; Masahisa Yamada; Jürgen Wess; Masakazu Nishimura; Seiichi Komori
Three distinct muscarinic signalling pathways for cationic channel activation in mouse gut smooth muscle cells.
The Journal of physiology 2007;582(Pt 1):41-61.
2007: Takio Kitazawa; Kano Hashiba; Jinshan Cao; Toshihiro Unno; Seiichi Komori; Masahisa Yamada; Jürgen Wess; Tetsuro Taneike
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
European journal of pharmacology 2007;554(2-3):212-22.
2006: Toshihiro Unno; Hayato Matsuyama; Y Izumi; Masahisa Yamada; Jürgen Wess; Seiichi Komori
Roles of M2 and M3 muscarinic receptors in cholinergic nerve-induced contractions in mouse ileum studied with receptor knockout mice.
British journal of pharmacology 2006;149(8):1022-30.
2006: Toshihiro Unno; Hayato Matsuyama; Hiroyuki Okamoto; T Sakamoto; M Yamamoto; Y Tanahashi; Hai-Dun Yan; Seiichi Komori
Muscarinic cationic current in gastrointestinal smooth muscles: signal transduction and role in contraction.
Autonomic & autacoid pharmacology 2006;26(3):203-17.
2006: Takashi Sakamoto; Toshihiro Unno; Hayato Matsuyama; Mai Uchiyama; Mitsunobu Hattori; Masakazu Nishimura; Seiichi Komori
Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestine.
Journal of pharmacological sciences 2006;100(3):215-26.
2005: Toshihiro Unno; Hayato Matsuyama; Takashi Sakamoto; Mai Uchiyama; Yusuke Izumi; Hiroyuki Okamoto; Masahisa Yamada; Jürgen Wess; Seiichi Komori
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
British journal of pharmacology 2005;146(1):98-108.
2004: Hiroyuki Okamoto; Toshihiro Unno; Daisuke Arima; Maki Suzuki; Hai-Dun Yan; Hayato Matsuyama; Masakazu Nishimura; Seiichi Komori
Phospholipase C involvement in activation of the muscarinic receptor-operated cationic current in Guinea pig ileal smooth muscle cells.
Journal of pharmacological sciences 2004;95(2):203-13.
2003: Hai-Dun Yan; Hiroyuki Okamoto; Toshihiro Unno; Yaroslav D Tsytsyura; SA Prestwich; Seiichi Komori; Alexander V Zholos; Thomas B Bolton
Effects of G-protein-specific antibodies and G beta gamma subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.
British journal of pharmacology 2003;139(3):605-15.
2003: Toshihiro Unno; S-C Kwon; Hiroyuki Okamoto; Y Irie; Y Kato; Hayato Matsuyama; Seiichi Komori
Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscle.
British journal of pharmacology 2003;139(2):337-50.
2002: Noriaki Izumi; Hayato Matsuyama; Yoshio Yamamoto; Yasuro Atoji; Yoshitaka Suzuki; Toshihiro Unno; Tadashi Takewaki
Morphological and morphometrical characteristics of the esophageal intrinsic nervous system in the golden hamster.
European journal of morphology 2002;40(3):137-44.
2002: Hiroyuki Okamoto; SA Prestwich; S Asai; Toshihiro Unno; Thomas B Bolton; Seiichi Komori
Muscarinic agonist potencies at three different effector systems linked to the M(2) or M(3) receptor in longitudinal smooth muscle of guinea-pig small intestine.
British journal of pharmacology 2002;135(7):1765-75.
2002: Hideki Saito; Sharada Thapaliya; Hayato Matsuyama; Masakazu Nishimura; Toshihiro Unno; Seiichi Komori; Tadashi Takewaki
Reversible impairment of endothelium-dependent relaxation in golden hamster carotid arteries during hibernation.
The Journal of physiology 2002;540(Pt 1):285-94.
2002: Hayato Matsuyama; Toshihiro Unno; A M El-Mahmoudy; Seiichi Komori; H Kobayashi; Sharada Thapaliya; Tadashi Takewaki
Peptidergic and nitrergic inhibitory neurotransmissions in the hamster jejunum: regulation of vasoactive intestinal peptide release by nitric oxide.
Neuroscience 2002;110(4):779-88.
2000: Toshihiro Unno; T Inaba; H Ohashi; Tadashi Takewaki; Seiichi Komori
Role of Ca2+ mobilization in muscarinic receptor-mediated membrane depolarization in guinea pig ileal smooth muscle cells.
Japanese journal of pharmacology 2000;84(4):431-7.
2000: M Iwata; Toshihiro Unno; Nobuyuki Minamoto; H Ohashi; Seiichi Komori
Rabies virus infection prevents the modulation by alpha(2)-adrenoceptors, but not muscarinic receptors, of Ca(2+) channels in NG108-15 cells.
European journal of pharmacology 2000;404(1-2):79-88.
2000: S Kawarada; Toshihiro Unno; H Ohashi; Seiichi Komori
Neurotensin-induced Cl(-) current in guinea-pig dorsal root ganglion cells.
European journal of pharmacology 2000;404(1-2):69-78.
1999: Toshihiro Unno; Seiichi Komori; H Ohashi
Microtubule cytoskeleton involvement in muscarinic suppression of voltage-gated calcium channel current in guinea-pig ileal smooth muscle.
British journal of pharmacology 1999;127(7):1703-11.
1999: M Iwata; Seiichi Komori; Toshihiro Unno; Nobuyuki Minamoto; H Ohashi
Modification of membrane currents in mouse neuroblastoma cells following infection with rabies virus.
British journal of pharmacology 1999;126(8):1691-8.
1999: Toshihiro Unno; Seiichi Komori; H Ohashi
Characterization of neurotensin receptors in intestinal smooth muscle using a nonpeptide antagonist.
European journal of pharmacology 1999;369(1):73-80.
1998: Toshihiro Unno; H Shingu; M Isogai; Seiichi Komori; H Ohashi
Potentiation by neurotensin of carbachol-induced tension development in beta-escin-skinned smooth muscle of guinea-pig ileum.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1998;60(11):1227-32.
1998: Toshihiro Unno; D J Beech; Seiichi Komori; H Ohashi
Inhibitors of spasmogen-induced Ca2+ channel suppression in smooth muscle cells from small intestine.
British journal of pharmacology 1998;125(4):667-74.
1998: M Kohda; Seiichi Komori; Toshihiro Unno; H Ohashi
Carbachol-induced oscillations in membrane potential and [Ca2+]i in guinea-pig ileal smooth muscle cells.
The Journal of physiology 1998;511 ( Pt 2)():559-71.
1998: Seiichi Komori; Toshihiro Unno; T Nakayama; H Ohashi
M2 and M3 muscarinic receptors couple, respectively, with activation of nonselective cationic channels and potassium channels in intestinal smooth muscle cells.
Japanese journal of pharmacology 1998;76(2):213-8.
1997: M Kohda; Seiichi Komori; Toshihiro Unno; H Ohashi
Characterization of action potential-triggered [Ca2+]i transients in single smooth muscle cells of guinea-pig ileum.
British journal of pharmacology 1997;122(3):477-86.
1997: Seiichi Komori; Toshihiro Unno; H Ohashi
Pharmacological properties of non-adrenergic, non-cholinergic inhibitory transmission in chicken gizzard.
British journal of pharmacology 1997;121(3):572-8.
1996: Seiichi Komori; M Iwata; Toshihiro Unno; H Ohashi
Modulation of carbachol-induced [Ca2+]i oscillations by Ca2+ influx in single intestinal smooth muscle cells.
British journal of pharmacology 1996;119(2):245-52.
1996: Toshihiro Unno; Seiichi Komori; H Ohashi
Some evidence against the involvement of arachidonic acid in muscarinic suppression of voltage-gated calcium channel current in guinea-pig ileal smooth muscle cells.
British journal of pharmacology 1996;119(2):213-22.
1996: H Ohashi; K Tanaka; N Kiuchi; Toshihiro Unno; Seiichi Komori
Modulation of peristalsis by neurotensin in isolated guinea-pig intestinal segments.
European journal of pharmacology 1996;301(1-3):129-36.
1996: M Kohda; Seiichi Komori; Toshihiro Unno; H Ohashi
Carbachol-induced [Ca2+]i oscillations in single smooth muscle cells of guinea-pig ileum.
The Journal of physiology 1996;492 ( Pt 2)():315-28.
1996: R Hasan; Seiichi Komori; Toshihiro Unno; H Ohashi
Pharmacological characterization of adrenoceptors mediating contractile and relaxant responses to noradrenaline in the longitudinal muscle of guinea-pig ileum.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1996;58(3):235-41.
1995: Toshihiro Unno; Seiichi Komori; H Ohashi
Inhibitory effect of muscarinic receptor activation on Ca2+ channel current in smooth muscle cells of guinea-pig ileum.
The Journal of physiology 1995;484 ( Pt 3)():567-81.
1995: Seiichi Komori; M Itagaki; Toshihiro Unno; H Ohashi
Caffeine and carbachol act on common Ca2+ stores to release Ca2+ in guinea-pig ileal smooth muscle.
European journal of pharmacology 1995;277(2-3):173-80.
1995: M Itagaki; Seiichi Komori; Toshihiro Unno; B Syuto; H Ohashi
Possible involvement of a small G-protein sensitive to exoenzyme C3 of Clostridium botulinum in the regulation of myofilament Ca2+ sensitivity in beta-escin skinned smooth muscle of guinea pig ileum.
Japanese journal of pharmacology 1995;67(1):1-7.
1994: H Ohashi; Tadashi Takewaki; Toshihiro Unno; Seiichi Komori
Mechanical and current responses to neurotensin in the smooth muscle of guinea-pig intestine.
Journal of autonomic pharmacology 1994;14(3):239-51.
1993: H Ohashi; Tadashi Takewaki; Toshihiro Unno; Seiichi Komori
Development of vagal innervation to the muscle of the avian gizzard.
Journal of the autonomic nervous system 1993;42(3):233-40.