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Derya Unutmaz

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Justin P Edwards; Hodaka Fujii; Derya Unutmaz; Angela X Zhou; John Creemers; Ethan M Shevach
Regulation of the Expression of GARP/Latent TGF-β1 Complexes on Mouse T Cells and Their Role in Regulatory T Cell and Th17 Differentiation.
Angela X Zhou; Hodaka Fujii; Lina Kozhaya; Derya Unutmaz
GARP-TGF-β Complexes Negatively Regulate Regulatory T Cell Development and Maintenance of Peripheral CD4+ T Cells In Vivo.
Francis Alonzo; Ashley L DuMont; Lina Kozhaya; Nathaniel R Landau; David G Myszka; Stephen A Rawlings; Tamara Reyes-Robles; Derya Unutmaz; Victor J Torres
CCR5 is a receptor for Staphylococcus aureus leukotoxin ED.

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2013: Justin P Edwards; Hodaka Fujii; Derya Unutmaz; Angela X Zhou; John Creemers; Ethan M Shevach
Regulation of the Expression of GARP/Latent TGF-β1 Complexes on Mouse T Cells and Their Role in Regulatory T Cell and Th17 Differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(11):5506-15.
2013: Angela X Zhou; Hodaka Fujii; Lina Kozhaya; Derya Unutmaz
GARP-TGF-β Complexes Negatively Regulate Regulatory T Cell Development and Maintenance of Peripheral CD4+ T Cells In Vivo.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(10):5057-64.
2013: Francis Alonzo; Ashley L DuMont; Lina Kozhaya; Nathaniel R Landau; David G Myszka; Stephen A Rawlings; Tamara Reyes-Robles; Derya Unutmaz; Victor J Torres
CCR5 is a receptor for Staphylococcus aureus leukotoxin ED.
Nature 2013;493(7430):51-5.
2013: Qi Wan; Shi Zhong; Keren Imberg; Lina Kozhaya; Michelle Krogsgaard; Frances Mercer; Derya Unutmaz
Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors.
PloS one 2013;8(2):e56302.
2012: Sylvia Adams; Deborah Axelrod; Nina Bhardwaj; Luis Chiriboga; Silvia C Formenti; Judith D Goldberg; Tsivia Hochman; Lina Kozhaya; Leonard Liebes; Frank Martiniuk; Tze-Chiang Meng; Yelena Novik; Nicholas Shuman; James Speyer; Amy Tiersten; Derya Unutmaz; Sandra Demaria
Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(24):6748-57.
2012: Zandrea Ambrose; Alan Engelman; Stephen H Hughes; KyeongEun Lee; James Matous; Jean Ndjomou; Ilker Oztop; Taichiro Takemura; Derya Unutmaz; Hongzhan Xu; Vineet N KewalRamani
Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection.
Journal of virology 2012;86(8):4708-14.
2011: Qi Wan; Thaddeus J Carlson; Ivana M Djuretic; Aimee ElHed; Lina Kozhaya; Radha Ramesh; Mark S Sundrud; Derya Unutmaz
Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells.
The Journal of experimental medicine 2011;208(9):1875-87.
2011: Alka Khaitan; Derya Unutmaz
Revisiting immune exhaustion during HIV infection.
Current HIV/AIDS reports 2011;8(1):4-11.
2011: Ashley L Dumont; Tyler K Nygaard; Robert L Watkins; Amanda Smith; Lina Kozhaya; Barry N Kreiswirth; Bo Shopsin; Derya Unutmaz; Jovanka M Voyich; Victor J Torres
Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis.
Molecular microbiology 2011;79(3):814-25.
2010: Nicolas Manel; Brandon Hogstad; Yaming Wang; David E Levy; Derya Unutmaz; Dan R Littman
A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.
Nature 2010;467(7312):214-7.
2010: KyeongEun Lee; Zandrea Ambrose; Thomas D Martin; Ilker Oztop; Alok Mulky; John G Julias; Nick Vandegraaff; Joerg G Baumann; Rui Wang; Wendy Yuen; Taichiro Takemura; Kenneth Shelton; Ichiro Taniuchi; Yuan Li; Joseph Sodroski; Dan R Littman; John M Coffin; Stephen H Hughes; Derya Unutmaz; Alan Engelman; Vineet N KewalRamani
Flexible use of nuclear import pathways by HIV-1.
Cell host & microbe 2010;7(3):221-33.
2010: Aimee El Hed; Alka Khaitan; Lina Kozhaya; Nicolas Manel; Demetre Daskalakis; William Borkowsky; Fred Valentine; Dan R Littman; Derya Unutmaz
Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection.
The Journal of infectious diseases 2010;201(6):843-54.
2010: Aimee Elhed; Derya Unutmaz
Th17 cells and HIV infection.
Current opinion in HIV and AIDS 2010;5(2):146-50.
2010: Vyacheslav Furtak; Alok Mulky; Stephen A Rawlings; Lina Kozhaya; KyeongEun Lee; Vineet N KewalRamani; Derya Unutmaz
Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity.
PloS one 2010;5(2):e9081.
2010: Frances Mercer; Lina Kozhaya; Derya Unutmaz
Expression and function of TNF and IL-1 receptors on human regulatory T cells.
PloS one 2010;5(1):e8639.
2009: Derya Unutmaz; Bali Pulendran
The gut feeling of Treg cells: IL-10 is the silver lining during colitis.
Nature immunology 2009;10(11):1141-3.
2009: Rui Wang; Lina Kozhaya; Frances Mercer; Alka Khaitan; Hodaka Fujii; Derya Unutmaz
Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13439-44.
2009: Dat Q Tran; John Andersson; Rui Wang; Heather Ramsey; Derya Unutmaz; Ethan M Shevach
GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13445-50.
2009: Anna Balato; Derya Unutmaz; Anthony Gaspari
Natural killer T cells: an unconventional T-cell subset with diverse effector and regulatory functions.
The Journal of investigative dermatology 2009;129(7):1628-42.
2009: Mark S Sundrud; Sergei B Koralov; Markus Feuerer; Dinis Calado; Aimee Elhed Kozhaya; Ava Rhule-Smith; Rachel E Lefebvre; Derya Unutmaz; Ralph Mazitschek; Hanspeter Waldner; Malcolm Whitman; Tracy Keller; Anjana Rao
Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.
Science (New York, N.Y.) 2009;324(5932):1334-8.
2009: Derya Unutmaz
RORC2: the master of human Th17 cell programming.
European journal of immunology 2009;39(6):1452-5.
2009: Michael L Vetter; Megan E Johnson; Amanda K Antons; Derya Unutmaz; Richard T D'Aquila
Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity.
PLoS pathogens 2009;5(2):e1000292.
2009: Frances Mercer; Derya Unutmaz
The biology of FoxP3: a key player in immune suppression during infections, autoimmune diseases and cancer.
Advances in experimental medicine and biology 2009;665():47-59.
2009: Jose F Camargo; Marlon P Quinones; Srinivas Mummidi; Sowmya Srinivas; Alvaro A Gaitan; Kazi Begum; Fabio Jimenez; Scott VanCompernolle; Derya Unutmaz; Seema Ahuja; Sunil Ahuja
CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):171-82.
2008: Shannon Faley; Kevin Seale; Jacob Hughey; David K Schaffer; Scott VanCompernolle; Brett A McKinney; Franz Baudenbacher; Derya Unutmaz; John P Wikswo
Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel.
Lab on a chip 2008;8(10):1700-12.
2008: Qi Jiang; Liguo Zhang; Rui Wang; Jerry Jeffrey; Michael L Washburn; Dedeke Brouwer; Selena Barbour; Grigoriy I Kovalev; Derya Unutmaz; Lishan Su
FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo.
Blood 2008;112(7):2858-68.
2008: Nicolas Manel; Derya Unutmaz; Dan R Littman
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat.
Nature immunology 2008;9(6):641-9.
2008: Michael D Gober; Rita Fishelevich; Yuming Zhao; Derya Unutmaz; Anthony Gaspari
Human natural killer T cells infiltrate into the skin at elicitation sites of allergic contact dermatitis.
The Journal of investigative dermatology 2008;128(6):1460-9.
2008: Amanda K Antons; Rui Wang; Kyra Oswald-Richter; Michelle Tseng; Christopher W Arendt; Spyros A Kalams; Derya Unutmaz
Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):764-73.
2008: Amanda K Antons; Rui Wang; Spyros A Kalams; Derya Unutmaz
Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals.
PloS one 2008;3(8):e2952.
2008: Rui Wang; Qi Wan; Lina Kozhaya; Hodaka Fujii; Derya Unutmaz
Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression.
PloS one 2008;3(7):e2705.
2008: Derya Unutmaz; Jan Vilcek
IRF1: a deus ex machina in TH1 differentiation.
Nature immunology 2008;9(1):9-10.
2007: Victor J Torres; Scott VanCompernolle; Mark S Sundrud; Derya Unutmaz; Timothy L Cover
Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5433-40.
2007: Srinivas Mummidi; Lisa M Adams; Scott VanCompernolle; Mrunal Kalkonde; Jose F Camargo; Hemant Kulkharni ; Adam S Bellinger; Gregory Bonello; Hiromi Tagoh; Seema Ahuja; Derya Unutmaz; Sunil Ahuja
Production of specific mRNA transcripts, usage of an alternate promoter, and octamer-binding transcription factors influence the surface expression levels of the HIV coreceptor CCR5 on primary T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5668-81.
2007: Kyra Oswald-Richter; Stacy M Grill; Mindy Leelawong; Michelle Tseng; Spyros A Kalams; Todd Hulgan; David W Haas; Derya Unutmaz
Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection.
PLoS pathogens 2007;3(4):e58.
2007: Holly M Scott Algood; Victor J Torres; Derya Unutmaz; Timothy L Cover
Resistance of primary murine CD4+ T cells to Helicobacter pylori vacuolating cytotoxin.
Infection and immunity 2007;75(1):334-41.
2006: Shekhar Srivastava; Zhai Li; Kyung Ko; Papiya Choudhury; Mamdouh Albaqumi; Amanda K Johnson; Ying Yan; Jonathan M Backer; Derya Unutmaz; William A Coetzee; Edward Y Skolnik
Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells.
Molecular cell 2006;24(5):665-75.
2006: Kyra Oswald-Richter; Victor J Torres; Mark S Sundrud; Scott VanCompernolle; Timothy L Cover; Derya Unutmaz
Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells.
Journal of virology 2006;80(23):11767-75.
2006: David W Haas; Daniel E Geraghty; Janet Andersen; Jessica Mar; Alison A Motsinger; Richard T D'Aquila; Derya Unutmaz; Constance A Benson; Marylyn Ritchie; Alan Landay
Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study.
The Journal of infectious diseases 2006;194(8):1098-107.
2006: Jelena S Bezbradica; Laura E Gordy; Aleksandar Stanic; Srdjan Dragovic; Timothy Hill; Jacek Hawiger; Derya Unutmaz; Luc Van Kaer; Sebastian JOYCE
Granulocyte-macrophage colony-stimulating factor regulates effector differentiation of invariant natural killer T cells during thymic ontogeny.
Immunity 2006;25(3):487-97.
2006: Shekhar Srivastava; Kyung Ko; Papiya Choudhury; Zhai Li; Amanda K Johnson; Vivek Nadkarni; Derya Unutmaz; William A Coetzee; Edward Y Skolnik
Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells.
Molecular and cellular biology 2006;26(15):5595-602.
2006: Stephanie Dillon; Sudhanshu Agrawal; Kaustuv Banerjee; John J Letterio; Timothy L Denning; Kyra Oswald-Richter; Deborah J Kasprowicz; Kathryn Kellar; Jeff Pare; Thomas Van Dyke; Steven Ziegler; Derya Unutmaz; Bali Pulendran
Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.
The Journal of clinical investigation 2006;116(4):916-28.
2006: Karla A Eger; Mark S Sundrud; Alison A Motsinger; Michelle Tseng; Luc Van Kaer; Derya Unutmaz
Human natural killer T cells are heterogeneous in their capacity to reprogram their effector functions.
PloS one 2006;1():e50.
2005: Mark S Sundrud; Scott VanCompernolle; Karla A Eger; Tullia C Bruno; Arun Subramaniam; Srinivas Mummidi; Sunil Ahuja; Derya Unutmaz
Transcription factor GATA-1 potently represses the expression of the HIV-1 coreceptor CCR5 in human T cells and dendritic cells.
Blood 2005;106(10):3440-8.
2005: Scott VanCompernolle; R Jeffery Taylor; Kyra Oswald-Richter; Jiyang Jiang; Bryan E Youree; John H Bowie; Michael J Tyler; J Michael Conlon; David Wade; Christopher Aiken; Terence S Dermody; Vineet N KewalRamani; Louise A Rollins-Smith; Derya Unutmaz
Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells.
Journal of virology 2005;79(18):11598-606.
2005: Gianluca Carlesso; Eugene Kozlov; Ales Prokop; Derya Unutmaz; Jeffrey M Davidson
Nanoparticulate system for efficient gene transfer into refractory cell targets.
Biomacromolecules 2005;6(3):1185-92.
2005: Jelena S Bezbradica; Aleksandar Stanic; Naoto Matsuki; Helene Bour-Jordan; Jeffrey A Bluestone; James W Thomas; Derya Unutmaz; Luc Van Kaer; Sebastian JOYCE
Distinct roles of dendritic cells and B cells in Va14Ja18 natural T cell activation in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4696-705.
2005: Jianbo Chen; Que Dang; Derya Unutmaz; Vinay K Pathak; Frank Maldarelli; Douglas Powell; Wei-Shau Hu
Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: preference in virus entry is important but is not the sole factor.
Journal of virology 2005;79(7):4140-9.
2005: Karla A Eger; Derya Unutmaz
The innate immune system and HIV pathogenesis.
Current HIV/AIDS reports 2005;2(1):10-5.
2004: Qin Yu; Darlene Chen; Renate König; Roberto Mariani; Derya Unutmaz; Nathaniel R Landau
APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication.
The Journal of biological chemistry 2004;279(51):53379-86.
2004: Jörg G Baumann; Derya Unutmaz; Michael D Miller; Sabine K J Breun; Stacy M Grill; Jane Mirro; Dan R Littman; Alan Rein; Vineet N KewalRamani
Murine T cells potently restrict human immunodeficiency virus infection.
Journal of virology 2004;78(22):12537-47.
2004: Kyra Oswald-Richter; Stacy M Grill; Nikki Shariat; Mindy Leelawong; Mark S Sundrud; David W Haas; Derya Unutmaz
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells.
PLoS biology 2004;2(7):E198.
2004: Karla A Eger; Derya Unutmaz
Perturbation of natural killer cell function and receptors during HIV infection.
Trends in microbiology 2004;12(7):301-3.
2004: Kyra Oswald-Richter; Stacy M Grill; Mindy Leelawong; Derya Unutmaz
HIV infection of primary human T cells is determined by tunable thresholds of T cell activation.
European journal of immunology 2004;34(6):1705-14.
2004: Mark S Sundrud; Victor J Torres; Derya Unutmaz; Timothy L Cover
Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(20):7727-32.
2004: Que Dang; Jianbo Chen; Derya Unutmaz; John M Coffin; Vinay K Pathak; Douglas Powell; Vineet N KewalRamani; Frank Maldarelli; Wei-Shau Hu
Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):632-7.
2003: Todd Hulgan; John P Donahue; Charlene Hawkins; Derya Unutmaz; Richard T D'Aquila; Stephen Raffanti; Fred Nicotera; Peter Rebeiro; Husamettin Erdem; Melissa Rueff; David W Haas
Implications of T-cell P-glycoprotein activity during HIV-1 infection and its therapy.
Journal of acquired immune deficiency syndromes (1999) 2003;34(2):119-26.
2003: Mark S Sundrud; Stacy M Grill; Donghui Ni; Kinya Nagata; Sefik Alkan; Arun Subramaniam; Derya Unutmaz
Genetic reprogramming of primary human T cells reveals functional plasticity in Th cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(7):3542-9.
2003: Derya Unutmaz
NKT cells and HIV infection.
Microbes and infection / Institut Pasteur 2003;5(11):1041-7.
2003: Daewoong Jo; Qing Lin; Abudi Nashabi; Deborah J Mays; Derya Unutmaz; Jennifer A Pietenpol; H Earl Ruley
Cell cycle-dependent transduction of cell-permeant Cre recombinase proteins.
Journal of cellular biochemistry 2003;89(4):674-87.
2003: Alison A Motsinger; Agnes M Azimzadeh; Aleksandar Stanic; R Paul Johnson; Luc Van Kaer; Sebastian JOYCE; Derya Unutmaz
Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cells.
Journal of virology 2003;77(14):8153-8.
2003: David McDonald; Li Wu; Stacy M Bohks; Vineet N KewalRamani; Derya Unutmaz; Thomas J Hope
Recruitment of HIV and its receptors to dendritic cell-T cell junctions.
Science (New York, N.Y.) 2003;300(5623):1295-7.
2003: John P Donahue; David Dowdy; Krishna K Ratnam; Todd Hulgan; James Price; Derya Unutmaz; Janet Nicotera; Stephen Raffanti; Mark Becker; David W Haas
Effects of nelfinavir and its M8 metabolite on lymphocyte P-glycoprotein activity during antiretroviral therapy.
Clinical pharmacology and therapeutics 2003;73(1):78-86.
2002: Steffen Jung; Derya Unutmaz; Phillip Wong; Gen-Ichiro Sano; Kenia De los Santos; Tim D. Sparwasser; Shengji Wu; Srilatha Vuthoori; Kyung Ko; Fidel Zavala; Eric G Pamer; Dan R Littman; Richard Lang
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.
Immunity 2002;17(2):211-20.
2002: Li Wu; Thomas D Martin; Rosemay Vazeux; Derya Unutmaz; Vineet N KewalRamani
Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission.
Journal of virology 2002;76(12):5905-14.
2002: Christopher A Lundquist; Minoru Tobiume; Jing Zhou; Derya Unutmaz; Christopher Aiken
Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.
Journal of virology 2002;76(9):4625-33.
2002: Alison A Motsinger; David W Haas; Aleksandar Stanic; Luc Van Kaer; Sebastian JOYCE; Derya Unutmaz
CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection.
The Journal of experimental medicine 2002;195(7):869-79.
2002: Li Wu; Arman Bashirova; Thomas D Martin; Loreley A Villamide; Erin Mehlhop; Andrei O Chertov; Derya Unutmaz; Melissa Pope; Mary Carrington; Vineet N KewalRamani
Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1568-73.
2001: Daewoong Jo; Abudi Nashabi; C Doxsee; Qing Lin; Derya Unutmaz; Jianzhu Chen; H Earl Ruley
Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase.
Nature biotechnology 2001;19(10):929-33.
2001: Derya Unutmaz
T cell signaling mechanisms that regulate HIV-1 infection.
Immunologic research 2001;23(2-3):167-77.
2000: Derya Unutmaz; W Xiang; Mary Jean Sunshine; J Campbell; E Butcher; Dan R Littman
The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3284-92.
2000: Z Sun; Derya Unutmaz; Yong-Rui Zou; Mary Jean Sunshine; Alessandra Pierani; Susan Brenner-Morton; R E Mebius; Dan R Littman
Requirement for RORgamma in thymocyte survival and lymphoid organ development.
Science (New York, N.Y.) 2000;288(5475):2369-73.
1999: Derya Unutmaz; Vineet N KewalRamani; Shana Marmon; Dan R Littman
Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes.
The Journal of experimental medicine 1999;189(11):1735-46.
1999: Dan R Littman; Z Sun; Derya Unutmaz; Mary Jean Sunshine; H T Petrie; Yong-Rui Zou
Role of the nuclear hormone receptor ROR gamma in transcriptional regulation, thymocyte survival, and lymphoid organogenesis.
Cold Spring Harbor symposia on quantitative biology 1999;64():373-81.
1998: CM Hill; D Kwon; M Jones; C B Davis; Shana Marmon; Bruce L Daugherty; Julie A DeMartino; Martin S Springer; Derya Unutmaz; Dan R Littman
The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins.
Virology 1998;248(2):357-71.
1998: Derya Unutmaz; Vineet N KewalRamani; Dan R Littman
G protein-coupled receptors in HIV and SIV entry: new perspectives on lentivirus-host interactions and on the utility of animal models.
Seminars in immunology 1998;10(3):225-36.
1997: C B Davis; I Dikic; Derya Unutmaz; CM Hill; J Arthos; M A Siani; D A Thompson; J Schlessinger; Dan R Littman
Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5.
The Journal of experimental medicine 1997;186(10):1793-8.
1997: CM Hill; H Deng; Derya Unutmaz; Vineet N KewalRamani; Lisa Lallos; Miroslaw K Gorny; Susan Zolla-Pazner; Dan R Littman
Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor.
Journal of virology 1997;71(9):6296-304.
1997: H K Deng; Derya Unutmaz; Vineet N KewalRamani; Dan R Littman
Expression cloning of new receptors used by simian and human immunodeficiency viruses.
Nature 1997;388(6639):296-300.
1997: Derya Unutmaz; Dan R Littman
Expression pattern of HIV-1 coreceptors on T cells: implications for viral transmission and lymphocyte homing.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1615-8.
1996: H Deng; R Liu; Wilfried Ellmeier; S Choe; Derya Unutmaz; M Burkhart; P Di Marzio; S Marmon; R E Sutton; C M Hill; C B Davis; Stephen Peiper; T J Schall; Dan R Littman; Nathaniel R Landau
Identification of a major co-receptor for primary isolates of HIV-1.
Nature 1996;381(6584):661-6.