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Hiroaki Ushikoshi

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Yoshihisa Yamada; Takuma Aoyama; Hisayoshi Fujiwara; Takako Fujiwara; Masamitsu Iwasa; Makoto Kiso; Hiroyuki Kobayashi; Kazuhiko Nishigaki; Shohei Sumi; Genzou Takemura; Hiroaki Ushikoshi; Shinya Minatoguchi
Postinfarct active cardiac-targeted delivery of erythropoietin by liposomes with sialyl Lewis X repairs infarcted myocardium in rabbits.
Tomonori Kawaguchi; Masanori Kawasaki; Tomoki Kubota; Shinya Minatoguchi; Kazuhiko Nishigaki; Mieko Takasugi; Nobuhiro Takasugi; Genzou Takemura; Hiroaki Ushikoshi; Takuma Aoyama; Arihiro Hattori; Hiromitsu Kanamori; Richard L Verrier
In-hospital monitoring of T-wave alternans in a case of amiodarone-induced torsade de pointes: clinical and methodologic insights.
Nobuhiro Takasugi; Genzou Takemura; Hiroaki Ushikoshi; Kazuhiko Nishigaki; Mieko Takasugi; Takuma Aoyama; Arihiro Hattori; Hiromitsu Kanamori; Itta Kawamura; Masanori Kawasaki; Tomoki Kubota; Shinya Minatoguchi
Sudden reversible pacemaker failure in a patient with cardiac sarcoidosis: an unfortunate case of ventricular septal pacing.

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All Publications

2013: Yoshihisa Yamada; Takuma Aoyama; Hisayoshi Fujiwara; Takako Fujiwara; Masamitsu Iwasa; Makoto Kiso; Hiroyuki Kobayashi; Kazuhiko Nishigaki; Shohei Sumi; Genzou Takemura; Hiroaki Ushikoshi; Shinya Minatoguchi
Postinfarct active cardiac-targeted delivery of erythropoietin by liposomes with sialyl Lewis X repairs infarcted myocardium in rabbits.
American journal of physiology. Heart and circulatory physiology 2013;304(8):H1124-33.
2012: Tomonori Kawaguchi; Masanori Kawasaki; Tomoki Kubota; Shinya Minatoguchi; Kazuhiko Nishigaki; Mieko Takasugi; Nobuhiro Takasugi; Genzou Takemura; Hiroaki Ushikoshi; Takuma Aoyama; Arihiro Hattori; Hiromitsu Kanamori; Richard L Verrier
In-hospital monitoring of T-wave alternans in a case of amiodarone-induced torsade de pointes: clinical and methodologic insights.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2012;14(9):1372-4.
2012: Nobuhiro Takasugi; Genzou Takemura; Hiroaki Ushikoshi; Kazuhiko Nishigaki; Mieko Takasugi; Takuma Aoyama; Arihiro Hattori; Hiromitsu Kanamori; Itta Kawamura; Masanori Kawasaki; Tomoki Kubota; Shinya Minatoguchi
Sudden reversible pacemaker failure in a patient with cardiac sarcoidosis: an unfortunate case of ventricular septal pacing.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2012;14(7):1061-2.
2012: Takashi Nakashima; Kazuhiko Nishigaki; Mieko Takasugi; Nobuhiro Takasugi; Genzou Takemura; Hiroaki Ushikoshi; Takuma Aoyama; Arihiro Hattori; Hiromitsu Kanamori; Masanori Kawasaki; Tomoki Kubota; Shinya Minatoguchi
'False-positive' intrathoracic impedance monitor alarm caused by amiodarone-induced hypothyroidism in a patient with cardiac resynchronization therapy-defibrillator.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2012;14(5):768-9.
2011: Yushan Bai; Masamitsu Iwasa; Takuma Aoyama; Hiroya Murakami; Kazuhiko Nishigaki; Shohei Sumi; Genzou Takemura; Bunji Uno; Hiroaki Ushikoshi; Yoshihisa Yamada; Shinya Minatoguchi
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
Clinical and experimental pharmacology & physiology 2011;38(10):658-65.
2011: Nobuhiro Takasugi; Genzou Takemura; Hiroaki Ushikoshi; Richard L Verrier; Takuma Aoyama; Arihiro Hattori; Masanori Kawasaki; Tomoki Kubota; Kazuhiko Nishigaki; Shinsuke Ojio; Mieko Takasugi; Shinya Minatoguchi
Relationship between T-wave alternans magnitude and T-wave amplitude before the onset of ventricular tachyarrhythmias during emergent reperfusion in acute coronary syndrome patients.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2011;13(10):1511-2; author reply 1512; discussion 1512-3.
2011: Masamitsu Iwasa; Itta Kawamura; Hiroyuki Kobayashi; Takuma Aoyama; Hisayoshi Fujiwara; Arihiro Hattori; Kazuhiko Nishigaki; Takeru Shiraki; Shohei Sumi; Genzou Takemura; Hiroaki Ushikoshi; Yoshihisa Yamada; Takahiko Yamaki; Shinji Yasuda; Shinya Minatoguchi
Both stimulation of GLP-1 receptors and inhibition of glycogenolysis additively contribute to a protective effect of oral miglitol against ischaemia-reperfusion injury in rabbits.
British journal of pharmacology 2011;164(1):119-31.
2011: Nobuhiro Takasugi; Tomoki Kubota; Kazuhiko Nishigaki; Richard L Verrier; Masanori Kawasaki; Mieko Takasugi; Hiroaki Ushikoshi; Arihiro Hattori; Shinsuke Ojio; Takuma Aoyama; Genzou Takemura; Shinya Minatoguchi
Continuous T-wave alternans monitoring to predict impending life-threatening cardiac arrhythmias during emergent coronary reperfusion therapy in patients with acute coronary syndrome.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2011;13(5):708-15.
2010: Shohei Sumi; Hiroyuki Kobayashi; Shinji Yasuda; Masamitsu Iwasa; Takahiko Yamaki; Yoshihisa Yamada; Hiroaki Ushikoshi; Arihiro Hattori; Takuma Aoyama; Kazuhiko Nishigaki; Genzou Takemura; Shinya Minatoguchi
Postconditioning effect of granulocyte colony-stimulating factor is mediated through activation of risk pathway and opening of the mitochondrial KATP channels.
American journal of physiology. Heart and circulatory physiology 2010;299(4):H1174-82.
2010: Masamitsu Iwasa; Hiroyuki Kobayashi; Shinji Yasuda; Itta Kawamura; Shohei Sumi; Yoshihisa Yamada; Takeru Shiraki; Takahiko Yamaki; Hiroaki Ushikoshi; Takuma Aoyama; Kazuhiko Nishigaki; Genzou Takemura; Takako Fujiwara; Hisayoshi Fujiwara; Shinya Minatoguchi
Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits.
Journal of cardiovascular pharmacology 2010;55(6):625-34.
2009: Hiroyuki Kobayashi; Shinji Yasuda; Narentuoya Bao; Masamitsu Iwasa; Itta Kawamura; Yoshihisa Yamada; Takahiko Yamaki; Syohei Sumi; Hiroaki Ushikoshi; Kazuhiko Nishigaki; Genzou Takemura; Takako Fujiwara; Hisayoshi Fujiwara; Shinya Minatoguchi
Postinfarct treatment with oxytocin improves cardiac function and remodeling via activating cell-survival signals and angiogenesis.
Journal of cardiovascular pharmacology 2009;54(6):510-9.
2009: Narentuoya Bao; Hiroaki Ushikoshi; Hiroyuki Kobayashi; Shinji Yasuda; Itta Kawamura; Masamitsu Iwasa; Takahiko Yamaki; Shohei Sumi; Kenshi Nagashima; Takuma Aoyama; Masanori Kawasaki; Kazuhiko Nishigaki; Genzou Takemura; Shinya Minatoguchi
Simvastatin reduces myocardial infarct size via increased nitric oxide production in normocholesterolemic rabbits.
Journal of cardiology 2009;53(1):102-7.
2008: Hiroyuki Kobayashi; Shinya Minatoguchi; Shinji Yasuda; Narentuoya Bao; Itta Kawamura; Masamitsu Iwasa; Takahiko Yamaki; Syohei Sumi; Yu Misao; Hiroaki Ushikoshi; Kazuhiko Nishigaki; Genzou Takemura; Takako Fujiwara; Yasuhiko Tabata; Hisayoshi Fujiwara
Post-infarct treatment with an erythropoietin-gelatin hydrogel drug delivery system for cardiac repair.
Cardiovascular research 2008;79(4):611-20.
2008: Shinichiro Tanaka; Kazuhiko Nishigaki; Shinsuke Ojio; Munenori Okubo; Shinji Yasuda; Yoshiyuki Ishihara; Tomoki Kubota; Nobuhiro Takasugi; Itta Kawamura; Takahiko Yamaki; Hiroaki Ushikoshi; Takuma Aoyama; Masanori Kawasaki; Genzou Takemura; Shinya Minatoguchi
Can negative cardiac effect of proton pump inhibitor and high-dose H2-blocker have clinical influence on patients with stable angina?
Journal of cardiology 2008;52(1):39-48.
2008: Munehiro Nakagawa; Genzou Takemura; Hiromitsu Kanamori; Kazuko Goto; Rumi Maruyama; Akiko Tsujimoto; Takamasa Ohno; Hideshi Okada; Atsushi Ogino; Masayasu Esaki; Shusaku Miyata; Longhu Li; Hiroaki Ushikoshi; Takuma Aoyama; Masanori Kawasaki; Kenshi Nagashima; Takako Fujiwara; Shinya Minatoguchi; Hisayoshi Fujiwara
Mechanisms by which late coronary reperfusion mitigates postinfarction cardiac remodeling.
Circulation research 2008;103(1):98-106.
2008: Shinichiro Tanaka; Chiharu Yokoyama; Itta Kawamura; Nobuhiro Takasugi; Tomoki Kubota; Hiroaki Ushikoshi; Takuma Aoyama; Masanori Kawasaki; Kazuhiko Nishigaki; Genzou Takemura; Shinya Minatoguchi
Conservative medication follow-up for over 20 years of a patient with ischemic heart disease after diagnosis of chronic total occlusion of the 3 main coronary arteries.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(7):1205-9.
2008: Masayasu Esaki; Genzou Takemura; Ken-ichiro Kosai; Tomoyuki Takahashi; Shusaku Miyata; Longhu Li; Kazuko Goto; Rumi Maruyama; Hideshi Okada; Hiromitsu Kanamori; Atsushi Ogino; Hiroaki Ushikoshi; Shinya Minatoguchi; Takako Fujiwara; Hisayoshi Fujiwara
Treatment with an adenoviral vector encoding hepatocyte growth factor mitigates established cardiac dysfunction in doxorubicin-induced cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2008;294(2):H1048-57.
2007: Xue-Hai Chen; Shinya Minatoguchi; Ken-ichiro Kosai; Kentaro Yuge; Tomoyuki Takahashi; Masazumi Arai; Ningyuan Wang; Yu Misao; Chuanjiang Lu; Hirohito Onogi; Hiroyuki Kobayashi; Shinji Yasuda; Masayasu Ezaki; Hiroaki Ushikoshi; Genzou Takemura; Takako Fujiwara; Hisayoshi Fujiwara
In vivo hepatocyte growth factor gene transfer reduces myocardial ischemia-reperfusion injury through its multiple actions.
Journal of cardiac failure 2007;13(10):874-83.
2007: Atsushi Ogino; Genzou Takemura; Hiromitsu Kanamori; Hideshi Okada; Rumi Maruyama; Shusaku Miyata; Masayasu Esaki; Munehiro Nakagawa; Takuma Aoyama; Hiroaki Ushikoshi; Masanori Kawasaki; Shinya Minatoguchi; Takako Fujiwara; Hisayoshi Fujiwara
Amlodipine inhibits granulation tissue cell apoptosis through reducing calcineurin activity to attenuate postinfarction cardiac remodeling.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2271-80.
2007: Hiromitsu Kanamori; Genzou Takemura; Yiwen Li; Hideshi Okada; Rumi Maruyama; Takuma Aoyama; Shusaku Miyata; Masayasu Esaki; Atsushi Ogino; Munehiro Nakagawa; Hiroaki Ushikoshi; Masanori Kawasaki; Shinya Minatoguchi; Hisayoshi Fujiwara
Inhibition of Fas-associated apoptosis in granulation tissue cells accompanies attenuation of postinfarction left ventricular remodeling by olmesartan.
American journal of physiology. Heart and circulatory physiology 2007;292(5):H2184-94.
2007: Yu Misao; Masazumi Arai; Takamasa Ohno; Hiroaki Ushikoshi; Hirohito Onogi; Hiroyuki Kobayashi; Genzou Takemura; Shinya Minatoguchi; Takako Fujiwara; Hisayoshi Fujiwara
Modification of post-myocardial infarction granulocyte-colony stimulating factor therapy with myelo-suppressives.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(4):580-90.
2006: Tomoyuki Takahashi; Takao Kawai; Hiroaki Ushikoshi; Satoshi Nagano; Hatsue Oshika; Makoto Inoue; Takahiro Kunisada; Genzou Takemura; Hisayoshi Fujiwara; Ken-ichiro Kosai
Identification and isolation of embryonic stem cell-derived target cells by adenoviral conditional targeting.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(5):673-83.
2006: Ngin Cin Khai; Tomoyuki Takahashi; Hiroaki Ushikoshi; Satoshi Nagano; Kentaro Yuge; Masayasu Esaki; Takao Kawai; Kazuko Goto; Yoshiteru Murofushi; Takako Fujiwara; Hisayoshi Fujiwara; Ken-ichiro Kosai
In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury and induces liver regeneration in mice: a comparative study to HGF.
Journal of hepatology 2006;44(6):1046-54.
2006: Shusaku Miyata; Genzou Takemura; Yukinori Kawase; Yiwen Li; Hideshi Okada; Rumi Maruyama; Hiroaki Ushikoshi; Masayasu Esaki; Hiromitsu Kanamori; Longhu Li; Yu Misao; Asaki Tezuka; Teruhiko Toyo-Oka; Shinya Minatoguchi; Takako Fujiwara; Hisayoshi Fujiwara
Autophagic cardiomyocyte death in cardiomyopathic hamsters and its prevention by granulocyte colony-stimulating factor.
The American journal of pathology 2006;168(2):386-97.
2005: Kentaro Yuge; Tomoyuki Takahashi; Satoshi Nagano; Yasuhiro Terazaki; Yoshiteru Murofushi; Hiroaki Ushikoshi; Takao Kawai; Ngin Cin Khai; Toshikazu Nakamura; Hisayoshi Fujiwara; Ken-ichiro Kosai
Adenoviral gene transduction of hepatocyte growth factor elicits inhibitory effects for hepatoma.
International journal of oncology 2005;27(1):77-85.
2005: Hiroaki Ushikoshi; Tomoyuki Takahashi; Xuehai Chen; Ngin Cin Khai; Masayasu Esaki; Kazuko Goto; Genzou Takemura; Rumi Maruyama; Shinya Minatoguchi; Takako Fujiwara; Satoshi Nagano; Kentaro Yuge; Takao Kawai; Yoshiteru Murofushi; Hisayoshi Fujiwara; Ken-ichiro Kosai
Local overexpression of HB-EGF exacerbates remodeling following myocardial infarction by activating noncardiomyocytes.
Laboratory investigation; a journal of technical methods and pathology 2005;85(7):862-73.
2005: Yu Misao; Masazumi Arai; Takamasa Ohno; Hiroaki Ushikoshi; Tomoyuki Takahashi; Genzou Takemura; Shinya Minatoguchi; Takako Fujiwara; Hisayoshi Fujiwara
Cyclophosphamide improves the function of post-infarct hearts by reducing old infarct area and accelerating the mobilization of CD34+ cells.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(6):763-5.
2004: Takao Kawai; Tomoyuki Takahashi; Masayasu Esaki; Hiroaki Ushikoshi; Satoshi Nagano; Hisayoshi Fujiwara; Ken-ichiro Kosai
Efficient cardiomyogenic differentiation of embryonic stem cell by fibroblast growth factor 2 and bone morphogenetic protein 2.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(7):691-702.