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Makoto Usui

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Kisho Ohtani; Kensuke Egashira; Ken-ichi Hiasa; Qingwei Zhao; Shiro Kitamoto; Minako Ishibashi; Makoto Usui; Shujiro Inoue; Yoshikazu Yonemitsu; Katsuo Sueishi; Masataka Sata; Masabumi Shibuya; Kenji Sunagawa
Blockade of vascular endothelial growth factor suppresses experimental restenosis after intraluminal injury by inhibiting recruitment of monocyte lineage cells.
Shiro Kitamoto; Kaku Nakano; Yasuhiko Hirouchi; Yoshiro Kohjimoto; Shunichi Kitajima; Makoto Usui; Shujiro Inoue; Kensuke Egashira
Cholesterol-lowering independent regression and stabilization of atherosclerotic lesions by pravastatin and by antimonocyte chemoattractant protein-1 therapy in nonhuman primates.
Kisho Ohtani; Makoto Usui; Kaku Nakano; Yoshiro Kohjimoto; Shunichi Kitajima; Yasuhiko Hirouchi; X-H Li; Shiro Kitamoto; Akira Takeshita; Kensuke Egashira
Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys.

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All Publications

2004: Kisho Ohtani; Kensuke Egashira; Ken-ichi Hiasa; Qingwei Zhao; Shiro Kitamoto; Minako Ishibashi; Makoto Usui; Shujiro Inoue; Yoshikazu Yonemitsu; Katsuo Sueishi; Masataka Sata; Masabumi Shibuya; Kenji Sunagawa
Blockade of vascular endothelial growth factor suppresses experimental restenosis after intraluminal injury by inhibiting recruitment of monocyte lineage cells.
Circulation 2004;110(16):2444-52.
2004: Shiro Kitamoto; Kaku Nakano; Yasuhiko Hirouchi; Yoshiro Kohjimoto; Shunichi Kitajima; Makoto Usui; Shujiro Inoue; Kensuke Egashira
Cholesterol-lowering independent regression and stabilization of atherosclerotic lesions by pravastatin and by antimonocyte chemoattractant protein-1 therapy in nonhuman primates.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(8):1522-8.
2004: Kisho Ohtani; Makoto Usui; Kaku Nakano; Yoshiro Kohjimoto; Shunichi Kitajima; Yasuhiko Hirouchi; X-H Li; Shiro Kitamoto; Akira Takeshita; Kensuke Egashira
Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys.
Gene therapy 2004;11(16):1273-82.
2004: Weihua Ni; Shiro Kitamoto; Minako Ishibashi; Makoto Usui; Shujiro Inoue; Ken-ichi Hiasa; Qingwei Zhao; Ken-ichi Nishida; Akira Takeshita; Kensuke Egashira
Monocyte chemoattractant protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(3):534-9.
2004: Chu Kataoka; Kensuke Egashira; Minako Ishibashi; Shujiro Inoue; Weihua Ni; Ken-ichi Hiasa; Shiro Kitamoto; Makoto Usui; Akira Takeshita
Novel anti-inflammatory actions of amlodipine in a rat model of arteriosclerosis induced by long-term inhibition of nitric oxide synthesis.
American journal of physiology. Heart and circulatory physiology 2004;286(2):H768-74.
2004: Kisho Ohtani; Kensuke Egashira; Makoto Usui; Minako Ishibashi; Ken-ichi Hiasa; Qingwei Zhao; M Aoki; Yasufumi Kaneda; R Morishita; Akira Takeshita
Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbits.
Gene therapy 2004;11(2):126-32.
2002: Shujiro Inoue; Kensuke Egashira; Weihua Ni; Shiro Kitamoto; Makoto Usui; Kisho Otani; Minako Ishibashi; Ken-ichi Hiasa; Ken-ichi Nishida; Akira Takeshita
Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice.
Circulation 2002;106(21):2700-6.
2002: Minako Ishibashi; Kensuke Egashira; Ken-ichi Hiasa; Shujiro Inoue; Weihua Ni; Qingwei Zhao; Makoto Usui; Shiro Kitamoto; Toshihiro Ichiki; Akira Takeshita
Antiinflammatory and antiarteriosclerotic effects of pioglitazone.
Hypertension 2002;40(5):687-93.
2002: Makoto Usui; Kensuke Egashira; Kisho Ohtani; Chu Kataoka; Minako Ishibashi; Ken-ichi Hiasa; Makoto Katoh; Qingwei Zhao; Shiro Kitamoto; Akira Takeshita
Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1838-40.
2002: Makoto Usui; Kensuke Egashira
[Angiotensin II receptor and oxidative stress].
Nihon rinsho. Japanese journal of clinical medicine 2002;60(10):1893-7.
2002: Emiko Mori; Kimihiro Komori; Terutoshi Yamaoka; Mitsugu Tanii; Chu Kataoka; Akira Takeshita; Makoto Usui; Kensuke Egashira; Keizo Sugimachi
Essential role of monocyte chemoattractant protein-1 in development of restenotic changes (neointimal hyperplasia and constrictive remodeling) after balloon angioplasty in hypercholesterolemic rabbits.
Circulation 2002;105(24):2905-10.
2002: Kensuke Egashira; Qingwei Zhao; Chu Kataoka; Kisho Ohtani; Makoto Usui; Israel F Charo; Ken-Ichi Nishida; Shujiro Inoue; Makoto Katoh; Toshihiro Ichiki; Akira Takeshita
Importance of monocyte chemoattractant protein-1 pathway in neointimal hyperplasia after periarterial injury in mice and monkeys.
Circulation research 2002;90(11):1167-72.
2002: Akihiro Masumoto; Masahiro Mohri; Hiroaki Shimokawa; Lemmy Urakami; Makoto Usui; Akira Takeshita
Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina.
Circulation 2002;105(13):1545-7.
2002: Mayuko Kubo-Inoue; Kensuke Egashira; Makoto Usui; Masao Takemoto; Kisho Ohtani; Makoto Katoh; Hiroaki Shimokawa; Akira Takeshita
Long-term inhibition of nitric oxide synthesis increases arterial thrombogenecity in rat carotid artery.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1478-84.
2002: Hongtao Sun; Masahiro Mohri; Hiroaki Shimokawa; Makoto Usui; Lemmy Urakami; Akira Takeshita
Coronary microvascular spasm causes myocardial ischemia in patients with vasospastic angina.
Journal of the American College of Cardiology 2002;39(5):847-51.
2002: Qingwei Zhao; Kensuke Egashira; Shujiro Inoue; Makoto Usui; Shiro Kitamoto; Weihua Ni; Minako Ishibashi; Ken-ichi Hiasa Ki; Toshihiro Ichiki; Masabumi Shibuya; Akira Takeshita
Vascular endothelial growth factor is necessary in the development of arteriosclerosis by recruiting/activating monocytes in a rat model of long-term inhibition of nitric oxide synthesis.
Circulation 2002;105(9):1110-5.
2002: Chu Kataoka; Kensuke Egashira; Shujiro Inoue; Masao Takemoto; Weihua Ni; Masamichi Koyanagi; Shiro Kitamoto; Makoto Usui; Kozo Kaibuchi; Hiroaki Shimokawa; Akira Takeshita
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats.
Hypertension 2002;39(2):245-50.
2001: Makoto Katoh; Kensuke Egashira; Chu Kataoka; Makoto Usui; M Koyanagi; Shiro Kitamoto; Yasushi Ohmachi; Akira Takeshita; Hiroshi Narita
Regression by ACE inhibition of arteriosclerotic changes induced by chronic blockade of NO synthesis in rats.
American journal of physiology. Heart and circulatory physiology 2001;280(5):H2306-12.
2000: Shiro Kitamoto; Kensuke Egashira; Chu Kataoka; Makoto Usui; Masamichi Koyanagi; Masao Takemoto; Akira Takeshita
Chronic inhibition of nitric oxide synthesis in rats increases aortic superoxide anion production via the action of angiotensin II.
Journal of hypertension 2000;18(12):1795-800.
2000: Makoto Usui; Kensuke Egashira; H Tomita; Masamichi Koyanagi; Makoto Katoh; Hiroaki Shimokawa; Motohiro Takeya; T Yoshimura; K Matsushima; Akira Takeshita
Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats.
Circulation 2000;101(3):305-10.
2000: Masamichi Koyanagi; Kensuke Egashira; Mayuko Kubo-Inoue; Makoto Usui; Shiro Kitamoto; H Tomita; Hiroaki Shimokawa; Akira Takeshita
Role of transforming growth factor-beta1 in cardiovascular inflammatory changes induced by chronic inhibition of nitric oxide synthesis.
Hypertension 2000;35(1 Pt 1):86-90.
1999: Makoto Usui; Kensuke Egashira; Shiro Kitamoto; Masamichi Koyanagi; Makoto Katoh; Chu Kataoka; Hiroaki Shimokawa; Akira Takeshita
Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats.
Hypertension 1999;34(4 Pt 1):546-51.
1998: Makoto Katoh; Kensuke Egashira; Makoto Usui; Toshihiro Ichiki; H Tomita; Hiroaki Shimokawa; H Rakugi; Akira Takeshita
Cardiac angiotensin II receptors are upregulated by long-term inhibition of nitric oxide synthesis in rats.
Circulation research 1998;83(7):743-51.
1998: H Tomita; Kensuke Egashira; Mayuko Kubo-Inoue; Makoto Usui; Masamichi Koyanagi; Hiroaki Shimokawa; Motohiro Takeya; T Yoshimura; Akira Takeshita
Inhibition of NO synthesis induces inflammatory changes and monocyte chemoattractant protein-1 expression in rat hearts and vessels.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(9):1456-64.
1998: Makoto Usui; Toshihiro Ichiki; Makoto Katoh; Kensuke Egashira; Akira Takeshita
Regulation of angiotensin II receptor expression by nitric oxide in rat adrenal gland.
Hypertension 1998;32(3):527-33.
1998: K Igarashi-Saito; Hiroyuki Tsutsui; S Yamamoto; Masanori P Takahashi; Shintaro Kinugawa; H Tagawa; Makoto Usui; M Yamamoto; Kensuke Egashira; Akira Takeshita
Role of SR Ca2+-ATPase in contractile dysfunction of myocytes in tachycardia-induced heart failure.
The American journal of physiology 1998;275(1 Pt 2):H31-40.
1998: Toshihiro Ichiki; Makoto Usui; M Kato; Yuko Funakoshi; Koji Ito; Kensuke Egashira; Akira Takeshita
Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide.
Hypertension 1998;31(1 Pt 2):342-8.
1997: Masao Takemoto; Kensuke Egashira; H Tomita; Makoto Usui; H Okamoto; A Kitabatake; Hiroaki Shimokawa; K Sueishi; Akira Takeshita
Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis.
Hypertension 1997;30(6):1621-7.
1997: T Namba; Hiroyuki Tsutsui; H Tagawa; Masanori P Takahashi; K Saito; Toshiyuki Kozai; Makoto Usui; Kyoko Imanaka-Yoshida; T Imaizumi; Akira Takeshita
Regulation of fibrillar collagen gene expression and protein accumulation in volume-overloaded cardiac hypertrophy.
Circulation 1997;95(10):2448-54.