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Mitsuyoshi Utsugi

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Shinichi Matsuzaki; Tamotsu Ishizuka; Takeshi Hisada; Haruka Aoki; Mayumi Komachi; Isao Ichimonji; Mitsuyoshi Utsugi; Akihiro Ono; Yasuhiko Koga; Kunio Dobashi; Hitoshi Kurose; Hideaki Tomura; Masatomo Mori; Fumikazu Okajima
Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells.
Haruka Aoki; Takeshi Hisada; Tamotsu Ishizuka; Mitsuyoshi Utsugi; Akihiro Ono; Yasuhiko Koga; noriaki sunaga; Takashi Nakakura; Fumikazu Okajima; Kunio Dobashi; Masatomo Mori
Protective effect of resolvin E1 on the development of asthmatic airway inflammation.
Mitsuyoshi Utsugi; Kunio Dobashi; Akihiro Ono; Tamotsu Ishizuka; Takeshi Hisada; Yasuhiko Koga; Yasuo Shimizu; Tadayoshi Kawata; Shin-Ichi Matsuzaki; Haruka Aoki; Yosuke Kamide; Masatomo Mori
JNK1 and JNK2 differently regulate IL-12 production in THP-1 macrophage cells.

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All Publications

2010: Shinichi Matsuzaki; Tamotsu Ishizuka; Takeshi Hisada; Haruka Aoki; Mayumi Komachi; Isao Ichimonji; Mitsuyoshi Utsugi; Akihiro Ono; Yasuhiko Koga; Kunio Dobashi; Hitoshi Kurose; Hideaki Tomura; Masatomo Mori; Fumikazu Okajima
Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(8):4863-72.
2010: Haruka Aoki; Takeshi Hisada; Tamotsu Ishizuka; Mitsuyoshi Utsugi; Akihiro Ono; Yasuhiko Koga; noriaki sunaga; Takashi Nakakura; Fumikazu Okajima; Kunio Dobashi; Masatomo Mori
Protective effect of resolvin E1 on the development of asthmatic airway inflammation.
Biochemical and biophysical research communications 2010;400(1):128-33.
2010: Mitsuyoshi Utsugi; Kunio Dobashi; Akihiro Ono; Tamotsu Ishizuka; Takeshi Hisada; Yasuhiko Koga; Yasuo Shimizu; Tadayoshi Kawata; Shin-Ichi Matsuzaki; Haruka Aoki; Yosuke Kamide; Masatomo Mori
JNK1 and JNK2 differently regulate IL-12 production in THP-1 macrophage cells.
Cytokine 2010;51(2):127-31.
2010: Kyoichi Kaira; noriaki sunaga; Yoshio Tomizawa; Noriko Yanagitani; Kimihiro Shimizu; Hisao Imai; Mitsuyoshi Utsugi; Yasuki Iwasaki; Hironobu Iijima; Hiroaki Tsurumaki; Akihiro Yoshii; N Fueki; Takeshi Hisada; Tamotsu Ishizuka; Ryusei Saito; Masatomo Mori
A phase II study of amrubicin, a synthetic 9-aminoanthracycline, in patients with previously treated lung cancer.
Lung cancer (Amsterdam, Netherlands) 2010;69(1):99-104.
2010: Kyoichi Kaira; noriaki sunaga; Noriko Yanagitani; Hisao Imai; Mitsuyoshi Utsugi; Yasuki Iwasaki; Kimihiro Shimizu; Hironobu Iijima; Hiroaki Tsurumaki; Yoshio Tomizawa; Takeshi Hisada; Tamotsu Ishizuka; Ryusei Saito; Masatomo Mori
Phase 2 study of S-1 plus carboplatin in patients with advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2010;68(2):253-7.
2010: Yasuo Shimizu; Kunio Dobashi; K Endou; A Ono; Noriko Yanagitani; Mitsuyoshi Utsugi; Takaaki Sano; Tamotsu Ishizuka; Kimihiro Shimizu; Shinji Tanaka; Masatomo Mori
Decreased interstitial FOXP3(+) lymphocytes in usual interstitial pneumonia with discrepancy of CXCL12/CXCR4 axis.
International journal of immunopathology and pharmacology 2010;23(2):449-61.
2010: S Matsuzaki; Yasuo Shimizu; Kunio Dobashi; Takeaki Nagamine; T Satoh; T Ohkubo; A Yokoyama; Y Ishii; T Kamiya; K Arakawa; S Makino; Mitsuyoshi Utsugi; Tamotsu Ishizuka; Shinji Tanaka; Kimihiro Shimizu; Masatomo Mori
Analysis on the co-localization of asbestos bodies and Fas or CD163 expression in asbestos lung tissue by in-air micro-pixe.
International journal of immunopathology and pharmacology 2010;23(1):1-11.
2009: Mitsuyoshi Utsugi
[Antigen presenting cells in allergy].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(11):2076-81.
2009: Kyoichi Kaira; noriaki sunaga; Noriko Yanagitani; Tadayoshi Kawata; Mitsuyoshi Utsugi; Kimihiro Shimizu; T Ebara; Hidemasa Kawamura; Tetsuo Nonaka; Hitoshi Ishikawa; Hideyuki Sakurai; Tatsuo Suga; Kenichiro Hara; Takeshi Hisada; Tamotsu Ishizuka; Takashi Nakano; Masatomo Mori
Phase I study of oral S-1 plus Cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer.
International journal of radiation oncology, biology, physics 2009;75(1):109-14.
2009: Mitsuyoshi Utsugi; Kunio Dobashi; Akihiro Ono; Tamotsu Ishizuka; Shin-ichi Matsuzaki; Takeshi Hisada; Yasuo Shimizu; Tadayoshi Kawata; Haruka Aoki; Yosuke Kamide; Masatomo Mori
PI3K p110beta positively regulates lipopolysaccharide-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5225-31.
2009: Noriko Yanagitani; Tamotsu Ishizuka; Mitsugu Hironaka; Kyoichi Kaira; Hisao Imai; Tadayoshi Kawata; Mitsuyoshi Utsugi; Yasuo Shimizu; noriaki sunaga; Takeshi Hisada; Masatomo Mori
[A case of cryptogenic organizing pneumonia with eosinophilic infiltration which was difficult to distinguish from nonspecific interstitial pneumonia].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2009;47(4):286-90.
2009: Kyoichi Kaira; Noriko Yanagitani; noriaki sunaga; Hisao Imai; Mitsuyoshi Utsugi; Tadayoshi Kawata; Takeshi Hisada; Kimihiro Shimizu; Tamotsu Ishizuka; Masatomo Mori
[Effective gemcitabine plus S-1 treatment in elderly non-small cell lung cancer patients with multiple bone metastases].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(2):299-300.
2009: Akihiro Ono; Mitsuyoshi Utsugi; Ken Masubuchi; Tamotsu Ishizuka; Tadayoshi Kawata; Yasuo Shimizu; Takeshi Hisada; Junji Hamuro; Masatomo Mori; Kunio Dobashi
Glutathione redox regulates TGF-beta-induced fibrogenic effects through Smad3 activation.
FEBS letters 2009;583(2):357-62.
2009: Noriko Yanagitani; Kyoichi Kaira; Tamotsu Ishizuka; Haruka Aoki; Mitsuyoshi Utsugi; Yasuo Shimizu; noriaki sunaga; Katsuaki Endou; Takeshi Hisada; Masatomo Mori
Multiple lung metastases presenting as ground-glass opacities in a pulmonary adenocarcinoma: a case report.
Cases journal 2009;2():6910.
2009: Yasuo Shimizu; Kunio Dobashi; Hideaki Imai; noriaki sunaga; A Ono; Takaaki Sano; Toshiaki Hikino; Kimihiro Shimizu; Shinji Tanaka; Tamotsu Ishizuka; Mitsuyoshi Utsugi; Masatomo Mori
CXCR4+FOXP3+CD25+ lymphocytes accumulate in CXCL12-expressing malignant pleural mesothelioma.
International journal of immunopathology and pharmacology 2009;22(1):43-51.
2008: Kyoichi Kaira; noriaki sunaga; Noriko Yanagitani; Hisao Imai; Mitsuyoshi Utsugi; Yasuo Shimizu; Tadayoshi Kawata; Takeshi Hisada; Kimihiro Shimizu; Takafumi Tsuchiya; Tamotsu Ishizuka; Masatomo Mori
[A case of elderly non-small cell lung cancer effectively treated by combined chemotherapy of gemcitabine and S-1].
Gan to kagaku ryoho. Cancer & chemotherapy 2008;35(9):1587-9.
2008: Yasuo Shimizu; Kunio Dobashi; T Kusakbe; Takeaki Nagamine; M Oikawa; T Satoh; J Haga; Y Ishii; T Ohkubo; T Kamiya; K Arakawa; T Sano; S Tanaka; K Shimizu; S Matsuzaki; Mitsuyoshi Utsugi; Masatomo Mori
In-air micro-particle induced X-ray emission analysis of asbestos and metals in lung tissue.
International journal of immunopathology and pharmacology 2008;21(3):567-76.
2008: Noriko Yanagitani; Kyoichi Kaira; Tamotsu Ishizuka; Haruka Aoki; Tadayoshi Kawata; Mitsuyoshi Utsugi; Yasuo Shimizu; noriaki sunaga; Takeshi Hisada; Masatomo Mori
[A case of large cell neuroendocrine carcinoma in a patient with sarcoidosis].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2008;46(7):574-7.
2008: Yasuo Shimizu; Kunio Dobashi; Yoko Yoshikawa; Shigeki Yabe; Seiichi Higuchi; Yoko Koike; Yoshinori Mita; Mitsuyoshi Utsugi; Katsuaki Endou; Kouichi Takahashi; Satoru Watanabe; Ryusei Saito; Masatomo Mori
Five-antituberculosis Drug-resistance Genes Detection Using Array System.
Journal of clinical biochemistry and nutrition 2008;42(3):228-34.
2008: Haruka Aoki; Takeshi Hisada; Tamotsu Ishizuka; Mitsuyoshi Utsugi; Tadayoshi Kawata; Yasuo Shimizu; Fumikazu Okajima; Kunio Dobashi; Masatomo Mori
Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthma.
Biochemical and biophysical research communications 2008;367(2):509-15.
2008: Kyoichi Kaira; noriaki sunaga; Noriko Yanagitani; Haruka Aoki; Tadayoshi Kawata; Mitsuyoshi Utsugi; Yasuo Shimizu; Kimihiro Shimizu; Takeshi Hisada; Tamotsu Ishizuka; Masatomo Mori
Phase I trial of oral S-1 plus gemcitabine in elderly patients with nonsmall cell lung cancer.
Anti-cancer drugs 2008;19(3):289-94.
2008: Satoshi Takakusaki; Tomohiro Kudo; Kuniaki Suzuki; Mitsuyoshi Utsugi; Takahumi Tsuchiya; Nobuyuki Shibusawa; Yasuyuki Shimoyama; Takeshi Hisada; Osamu Kawamura; Motoyasu Kusano; Masatomo Mori
[Intestinal pseudo-obstruction associated with polymyositis successfully treated with somatostatin analog].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2008;97(2):398-400.
2008: J J Zhao; Yasuo Shimizu; Kunio Dobashi; Tadayoshi Kawata; Akihiro Ono; Noriko Yanagitani; Kyoichi Kaira; Mitsuyoshi Utsugi; Takeshi Hisada; Tamotsu Ishizuka; Masatomo Mori
The relationship between oxidative stress and acid stress in adult patients with mild asthma.
Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología 2008;18(1):41-5.
2007: Tamotsu Ishizuka; Takeshi Hisada; Haruka Aoki; Noriko Yanagitani; Kyoichi Kaira; Mitsuyoshi Utsugi; Yasuo Shimizu; noriaki sunaga; Kunio Dobashi; Masatomo Mori
Gender and age risks for hoarseness and dysphonia with use of a dry powder fluticasone propionate inhaler in asthma.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 2007;28(5):550-6.
2007: Yoko Koike; Takeshi Hisada; Mitsuyoshi Utsugi; Tamotsu Ishizuka; Yasuo Shimizu; Akihiro Ono; Yukie Murata; Junji Hamuro; Masatomo Mori; Kunio Dobashi
Glutathione redox regulates airway hyperresponsiveness and airway inflammation in mice.
American journal of respiratory cell and molecular biology 2007;37(3):322-9.
2007: Ken Sato; Minoru Hayashi; Mitsuyoshi Utsugi; Tamotsu Ishizuka; Hitoshi Takagi; Masatomo Mori
Acute pancreatitis in a patient treated with micafungin.
Clinical therapeutics 2007;29(7):1468-73.
2007: Yasuo Shimizu; Kunio Dobashi; Takeshi Hisada; A Ono; Makoto Todokoro; Hironobu Iijima; Mitsuyoshi Utsugi; Seiichi Kakegawa; Kunihiko Iizuka; Tamotsu Ishizuka; Akihiro Morikawa; Masatomo Mori
Acute impact of volcanic ash on asthma symptoms and treatment.
International journal of immunopathology and pharmacology 2007;20(2 Suppl 2):9-14.
2007: Kyoichi Kaira; noriaki sunaga; Noriko Yanagitani; Hisao Imai; Mitsuyoshi Utsugi; Yasuo Shimizu; Hironobu Iijima; Yoshio Tomizawa; Takeshi Hisada; Tamotsu Ishizuka; Ryusei Saito; Masatomo Mori
A phase I dose-escalation study of S-1 plus carboplatin in patients with advanced non-small-cell lung cancer.
Anti-cancer drugs 2007;18(4):471-6.
2007: Yasuo Shimizu; Kunio Dobashi; Jian Jun Zhao; Tadayoshi Kawata; Akihiro Ono; Noriko Yanagitani; Kyoichi Kaira; Mitsuyoshi Utsugi; Takeshi Hisada; Tamotsu Ishizuka; Masatomo Mori
Proton pump inhibitor improves breath marker in moderate asthma with gastroesophageal reflux disease.
Respiration; international review of thoracic diseases 2007;74(5):558-64.
2006: Mitsuyoshi Utsugi; Kunio Dobashi; Tamotsu Ishizuka; Tadayoshi Kawata; Takeshi Hisada; Yasuo Shimizu; Akihiro Ono; Masatomo Mori
Rac1 negatively regulates lipopolysaccharide-induced IL-23 p19 expression in human macrophages and dendritic cells and NF-kappaB p65 trans activation plays a novel role.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4550-7.
2006: Yasuo Shimizu; Kunio Dobashi; Yoshinori Mita; Katsuaki Endou; Shogo Moriya; Kaoru Osano; Yoko Koike; Seiichi Higuchi; Shigeki Yabe; Mitsuyoshi Utsugi; Tamotsu Ishizuka; Takeshi Hisada; Tsugio Nakazawa; Masatomo Mori
DNA microarray genotyping of N-acetyltransferase 2 polymorphism using carbodiimide as the linker for assessment of isoniazid hepatotoxicity.
Tuberculosis (Edinburgh, Scotland) 2006;86(5):374-81.
2006: Yasuo Shimizu; Kunio Dobashi; Setsuo Kobayashi; Ichiro Ohki; Masahiko Tokushima; Motoyasu Kusano; Osamu Kawamura; Yasuyuki Shimoyama; Mitsuyoshi Utsugi; Masatomo Mori
High prevalence of gastroesophageal reflux disease with minimal mucosal change in asthmatic patients.
The Tohoku journal of experimental medicine 2006;209(4):329-36.
2006: Yasuo Shimizu; Kunio Dobashi; Setsuo Kobayashi; Ichiro Ohki; Masahiko Tokushima; Motoyasu Kusano; Osamu Kawamura; Yasuyuki Shimoyama; Mitsuyoshi Utsugi; noriaki sunaga; Tamotsu Ishizuka; Masatomo Mori
A proton pump inhibitor, lansoprazole, ameliorates asthma symptoms in asthmatic patients with gastroesophageal reflux disease.
The Tohoku journal of experimental medicine 2006;209(3):181-9.
2006: Mitsuyoshi Utsugi; Tamotsu Ishizuka; Takeshi Hisada; Yasuo Shimizu; Kunio Dobashi; Masatomo Mori
Acute respiratory failure associated with miliary tuberculosis successfully treated with sivelestat sodium hydrate.
Internal medicine (Tokyo, Japan) 2006;45(18):1069-70.
2006: Yasuo Shimizu; Hidemasa Kuwabara; Akihiro Ono; Seiichi Higuchi; Takeshi Hisada; Kunio Dobashi; Mitsuyoshi Utsugi; Yoshinori Mita; Masatomo Mori
Intracellular Th1/Th2 balance of pulmonary CD4(+) T cells in patients with active interstitial pneumonia evaluated by serum KL-6.
Immunopharmacology and immunotoxicology 2006;28(2):295-304.
2005: Tamotsu Ishizuka; Tadayoshi Kawata; Yasuo Shimizu; Mitsuyoshi Utsugi; Katsuaki Endou; Takeshi Hisada; Kunio Dobashi; Tsugio Nakazawa; Masatomo Mori
Safety and efficacy of extracorporeal granulocyte and monocyte adsorption apheresis in patients with severe persistent bronchial asthma.
Inflammation 2005;29(1):9-16.
2005: Kyoichi Kaira; Atsushi Takise; Go Kobayashi; Mitsuyoshi Utsugi; Takeo Horie; Takanori Mori; Hisao Imai; Masahito Inazawa; Masatomo Mori
Management of malignant pericardial effusion with instillation of mitomycin C in non-small cell lung cancer.
Japanese journal of clinical oncology 2005;35(2):57-60.
2004: Makoto Todokoro; Hiroyuki Mochizuki; Kenichi Tokuyama; Mitsuyoshi Utsugi; Kunio Dobashi; Masatomo Mori; Akihiro Morikawa
Effect of ozone exposure on intracellular glutathione redox state in cultured human airway epithelial cells.
Inflammation 2004;28(2):105-14.
2003: Mitsuyoshi Utsugi; Kunio Dobashi; Tamotsu Ishizuka; Katsuaki Endou; Junji Hamuro; Yukie Murata; Tsugio Nakazawa; Masatomo Mori
c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):628-35.
2003: Mitsuyoshi Utsugi; Kunio Dobashi; Tamotsu Ishizuka; Ken Masubuchi; Yasuo Shimizu; Tsugio Nakazawa; Masatomo Mori
C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts.
American journal of respiratory cell and molecular biology 2003;28(6):754-61.
2002: Mitsuyoshi Utsugi; Kunio Dobashi; Yasuhiko Koga; Ken Masubuchi; Yasuo Shimizu; Katsuaki Endou; Tsugio Nakazawa; Masatomo Mori
Ambroxol inhibits platelet-derived growth factor production in human monocytic cells.
European journal of pharmacology 2002;436(1-2):47-51.
2002: Mitsuyoshi Utsugi; Kunio Dobashi; Yasuhiko Koga; Yasuo Shimizu; Tamotsu Ishizuka; Kunihiko Iizuka; Junji Hamuro; Tsugio Nakazawa; Masatomo Mori
Glutathione redox regulates lipopolysaccharide-induced IL-12 production through p38 mitogen-activated protein kinase activation in human monocytes: role of glutathione redox in IFN-gamma priming of IL-12 production.
Journal of leukocyte biology 2002;71(2):339-47.
2001: Kunio Dobashi; M Aihara; T Araki; Yasuo Shimizu; Mitsuyoshi Utsugi; Kunihiko Iizuka; Yukie Murata; Junji Hamuro; Tsugio Nakazawa; Masatomo Mori
Regulation of LPS induced IL-12 production by IFN-gamma and IL-4 through intracellular glutathione status in human alveolar macrophages.
Clinical and experimental immunology 2001;124(2):290-6.
1999: T Masuo; Y Mita; K Dobashi; Y Koga; Mitsuyoshi Utsugi; M Akiyama; Y Umegae; M Mori
[Diaphragmatic hernia with omental vessels delineated by computed tomography].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 1999;37(6):495-8.