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Paul Utz

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TOP 3
David Furman; Huang Huang; Justin Jarrell; Vladimir Jojic; Brian Kidd; Daphne Koller; Peder Lund; Holden T Maecker; Jordan Price; Shai Shen-Orr; Tiffany Tse; Paul J Utz; Cornelia L Dekker; Mark M Davis
Apoptosis and other immune biomarkers predict influenza vaccine responsiveness.
Pearline Zhaoying Teo; Paul J Utz; Joseph A Mollick
Using the allergic immune system to target cancer: activity of IgE antibodies specific for human CD20 and MUC1.
Jordan V Price; Stephanie Tangsombatvisit; Paul J Utz; Madoo Varma; Guangyu Xu; Jiangtao Yu; Emily C Baechler; Or Gozani; Dan Levy; Chih Long Liu
On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions.

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All Publications

2013: David Furman; Huang Huang; Justin Jarrell; Vladimir Jojic; Brian Kidd; Daphne Koller; Peder Lund; Holden T Maecker; Jordan Price; Shai Shen-Orr; Tiffany Tse; Paul J Utz; Cornelia L Dekker; Mark M Davis
Apoptosis and other immune biomarkers predict influenza vaccine responsiveness.
Molecular systems biology 2013;9():659.
2012: Pearline Zhaoying Teo; Paul J Utz; Joseph A Mollick
Using the allergic immune system to target cancer: activity of IgE antibodies specific for human CD20 and MUC1.
Cancer immunology, immunotherapy : CII 2012;61(12):2295-309.
2012: Jordan V Price; Stephanie Tangsombatvisit; Paul J Utz; Madoo Varma; Guangyu Xu; Jiangtao Yu; Emily C Baechler; Or Gozani; Dan Levy; Chih Long Liu
On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions.
Nature medicine 2012;18(9):1434-40.
2012: Holden T Maecker; William H Robinson; Shai S Shen-Orr; Paul J Utz; Scott D Boyd; Matthew Hale; Tamsin M Lindstrom; C Garrison Fathman
New tools for classification and monitoring of autoimmune diseases.
Nature reviews. Rheumatology 2012;8(6):317-28.
2012: Jack T Lin; William H Robinson; Emily A Stein; Leon L Su; Paul J Utz; Michael T Wong; Krishna J Kalpathy; C Garrison Fathman
Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis.
Clinical immunology (Orlando, Fla.) 2012;142(2):127-38.
2012: Chih Long Liu; Gil Mandelbaum; Jacob M Rosenberg; Stephanie Tangsombatvisit; Ash A Alizadeh; Emily C Gillespie; Or Gozani; Paul J Utz
Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.
Arthritis research & therapy 2012;14(1):R25.
2011: Angela Landrigan; Michael T Wong; Paul J Utz
CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(6):3033-43.
2011: Regina K Cheung; Paul J Utz
Screening: CyTOF-the next generation of cell detection.
Nature reviews. Rheumatology 2011;7(9):502-3.
2011: Dan Levy; Chih Long Liu; Aaron M Newman; Paul J Utz; Ze Yang; Ash A Alizadeh; Or Gozani
A proteomic approach for the identification of novel lysine methyltransferase substrates.
Epigenetics & chromatin 2011;4():19.
2011: Scott M Tabakman; Stephanie Tangsombatvisit; Paul J Utz; Hailiang Wang; Bo Zhang; Justin A Jarrell; Lana Lau; Jordan Price; Joshua T Robinson; Sarah P Sherlock; Zhuo Chen; Hongjie Dai
Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range.
Nature communications 2011;2():466.
2011: Dan Levy; Alex J Kuo; Yanqi Chang; Uwe Schaefer; Christopher Kitson; Peggie Cheung; Alexsandra Espejo; Barry M Zee; Chih Long Liu; Stephanie Tangsombatvisit; Ruth I Tennen; Andrew Y Kuo; Song Tanjing; Regina Cheung; Katrin F Chua; Paul J Utz; Xiaobing Shi; Rab Prinjha; Kevin Lee; Benjamin A Garcia; Mark T Bedford; Alexander Tarakhovsky; Xiaodong Cheng; Or Gozani
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Nature immunology 2011;12(1):29-36.
2010: Michael T Wong; Jessica J Ye; Michael N Alonso; Angela Landrigan; Regina K Cheung; Edgar Engleman; Paul J Utz
Regulation of human Th9 differentiation by type I interferons and IL-21.
Immunology and cell biology 2010;88(6):624-31.
2010: Kareem L Graham; Lowen Y Lee; John P Higgins; Lawrence Steinman; Paul J Utz; Peggy P Ho
Treatment with a toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice.
Autoimmunity 2010;43(2):140-55.
2010: Nicole H Kattah; Michael G Kattah; Paul J Utz
The U1-snRNP complex: structural properties relating to autoimmune pathogenesis in rheumatic diseases.
Immunological reviews 2010;233(1):126-45.
2009: Jenny C F Wu; AJ Chruscinski; Vinicio A De Jesus Perez; Harvir Singh; Maria Pitsiouni; Marlene Rabinovitch; Paul J Utz; john cooke
Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor.
Journal of cellular biochemistry 2009;108(2):433-46.
2009: Jack T Lin; Neil Lineberry; Michael G Kattah; Leon L Su; Paul J Utz; C Garrison Fathman; Linda Wu
Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):5919-28.
2009: Donna L Thibault; Kareem L Graham; Lowen Y Lee; Imelda Balboni; Paul J Hertzog; Paul J Utz
Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus.
Arthritis research & therapy 2009;11(4):R112.
2008: Zhuo Chen; Scott M Tabakman; Andrew P Goodwin; Michael G Kattah; Dan Daranciang; Xinran Wang; Guangyu Zhang; Xiaolin Li; Zhuang Liu; Paul J Utz; Kaili Jiang; Shoushan Fan; Hongjie Dai
Protein microarrays with carbon nanotubes as multicolor Raman labels.
Nature biotechnology 2008;26(11):1285-92.
2008: Michael G Kattah; John Coller; Regina K Cheung; Neekaan Oshidary; Paul J Utz
HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules.
Nature medicine 2008;14(11):1284-9.
2008: Daniel H Li; Monte M Winslow; Thai M Cao; Albert H Chen; Corrine R Davis; Elizabeth D Mellins; Paul J Utz; Gerald R Crabtree; Jane R Parnes
Modulation of peripheral B cell tolerance by CD72 in a murine model.
Arthritis and rheumatism 2008;58(10):3192-204.
2008: Imelda Balboni; Cindy Limb; Jessica Tenenbaum; Paul J Utz
Evaluation of microarray surfaces and arraying parameters for autoantibody profiling.
Proteomics 2008;8(17):3443-9.
2008: Kareem L Graham; Lowen Y Lee; John P Higgins; Lawrence Steinman; Paul J Utz; Peggy P Ho
Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus.
Arthritis and rheumatism 2008;58(7):2098-104.
2008: Michael G Kattah; Michael T Wong; Matthew D Yocum; Paul J Utz
Cytokines secreted in response to Toll-like receptor ligand stimulation modulate differentiation of human Th17 cells.
Arthritis and rheumatism 2008;58(6):1619-29.
2008: Michael G Kattah; Paul J Utz; Imelda Balboni
Protein microarrays address the elephant in the room.
Clinical chemistry 2008;54(6):937-9.
2008: Katerina A Drouvalakis; Sarunya Bangsaruntip; Wolfgang Hueber; Leland G Kozar; Paul J Utz; Hongjie Dai
Peptide-coated nanotube-based biosensor for the detection of disease-specific autoantibodies in human serum.
Biosensors & bioelectronics 2008;23(10):1413-21.
2008: Donna L Thibault; Alvina D Chu; Kareem L Graham; Imelda Balboni; Lowen Y Lee; Cassidy Kohlmoos; Angela Landrigan; John P Higgins; Robert Tibshirani; Paul J Utz
IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice.
The Journal of clinical investigation 2008;118(4):1417-26.
2007: Adam G W Matthews; Alex J Kuo; Santiago Ramón-Maiques; Sunmi Han; Karen S Champagne; Dmitri N. Ivanov; Mercedes Gallardo; Dylan Carney; Peggie Cheung; David N Ciccone; Kay L Walter; Paul J Utz; Yang Shi; Tatiana G Kutateladze; WEI YANG; Or Gozani; Marjorie A Oettinger
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.
Nature 2007;450(7172):1106-10.
2007: Sumita Pennathur; Fabio Baldessari; Juan G Santiago; Michael G Kattah; Jonathan B Steinman; Paul J Utz
Free-solution oligonucleotide separation in nanoscale channels.
Analytical chemistry 2007;79(21):8316-22.
2007: Amit Bar-Or; Timothy L Vollmer; Jack Antel; Douglas L Arnold; Caroline Bodner; Denise I Campagnolo; Jill Gianettoni; Farzaneh Jalili; Norman Kachuck; Yves Lapierre; Masaaki Niino; Joel Oger; Mary Price; Susan Rhodes; William H Robinson; Fu-Dong Shi; Paul J Utz; Frank Valone; Leslie Weiner; Lawrence Steinman; Hideki Garren
Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial.
Archives of neurology 2007;64(10):1407-15.
2007: Steven M Chan; Andrew P Weng; Robert Tibshirani; Jon C Aster; Paul J Utz
Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia.
Blood 2007;110(1):278-86.
2007: Veronika Sharp; Paul J Utz
Technology insight: can autoantibody profiling improve clinical practice?
Nature clinical practice. Rheumatology 2007;3(2):96-103.
2007: Xiaobing Shi; Ioulia Kachirskaia; Kay L Walter; Jen-Hao A Kuo; Aimee Lake; Foteini Davrazou; Steve M Chan; David Martin; Ian M Fingerman; Scott D Briggs; LeAnn Howe; Paul J Utz; Tatiana G Kutateladze; Alexey A Lugovskoy; Mark T Bedford; Or Gozani
Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36.
The Journal of biological chemistry 2007;282(4):2450-5.
2006: Hideharu Sekine; Kareem L Graham; Shenru Zhao; Margaret K Elliott; Phillip Ruiz; Paul J Utz; Gary S Gilkeson
Role of MHC-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7423-34.
2006: Kareem L Graham; Maria Vaysberg; Annie Kuo; Paul J Utz
Autoantigen arrays for multiplex analysis of antibody isotypes.
Proteomics 2006;6(21):5720-4.
2006: Ricardo T Paniagua; Orr Sharpe; Peggy P Ho; Steven M Chan; Anna Chang; John P Higgins; Beren H Tomooka; Fiona M Thomas; Jason J Song; Stuart Goodman; David M Lee; Mark C Genovese; Paul J Utz; Lawrence Steinman; William H Robinson
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis.
The Journal of clinical investigation 2006;116(10):2633-42.
2006: Michael G Kattah; Golnaz R Alemi; Donna L Thibault; Imelda Balboni; Paul J Utz
A new two-color Fab labeling method for autoantigen protein microarrays.
Nature methods 2006;3(9):745-51.
2006: Steven M Chan; Janelle A Olson; Paul J Utz
Single-cell analysis of siRNA-mediated gene silencing using multiparameter flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(2):59-65.
2006: Imelda Balboni; Steven M Chan; Michael G Kattah; Jessica Tenenbaum; Atul Butte; Paul J Utz
Multiplexed protein array platforms for analysis of autoimmune diseases.
Annual review of immunology 2006;24():391-418.
2005: Steven M Chan; Paul J Utz
The challenge of analyzing the proteome in humans with autoimmune diseases.
Annals of the New York Academy of Sciences 2005;1062():61-8.
2005: Mingguo Huang; Hiroaki Ida; Makoto Kamachi; Nozomi Iwanaga; Yasumori Izumi; Fumiko Tanaka; Kouichiro Aratake; Kazuhiko Arima; Mami Tamai; Ayumi Hida; Hideki Nakamura; Tomoki Origuchi; Atsushi Kawakami; N Ogawa; S Sugai; Paul J Utz; Katsumi Eguchi
Detection of apoptosis-specific autoantibodies directed against granzyme B-induced cleavage fragments of the SS-B (La) autoantigen in sera from patients with primary Sjögren's syndrome.
Clinical and experimental immunology 2005;142(1):148-54.
2005: Wolfgang Hueber; Brian A Kidd; Beren H Tomooka; Byung J Lee; Bonnie Bruce; James F Fries; Grete Sønderstrup; Paul A Monach; Jan Wouter Drijfhout; Walther J van Venrooij; Paul J Utz; Mark C Genovese; William H Robinson
Antigen microarray profiling of autoantibodies in rheumatoid arthritis.
Arthritis and rheumatism 2005;52(9):2645-55.
2005: Kareem L Graham; Paul J Utz
Sources of autoantigens in systemic lupus erythematosus.
Current opinion in rheumatology 2005;17(5):513-7.
2005: C Garrison Fathman; Luis Soares; Steven M Chan; Paul J Utz
An array of possibilities for the study of autoimmunity.
Nature 2005;435(7042):605-11.
2005: Kareem L Graham; Donna L Thibault; Jonathan B Steinman; Lance Okeke; Peter N Kao; Paul J Utz
Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus.
Arthritis and rheumatism 2005;52(6):1684-93.
2005: Paul J Utz
Protein arrays for studying blood cells and their secreted products.
Immunological reviews 2005;204():264-82.
2005: Hiroaki Ida; Paul J Utz; Paul Anderson; Katsumi Eguchi
Granzyme B and natural killer (NK) cell death.
Modern rheumatology / the Japan Rheumatism Association 2005;15(5):315-22.
2005: Lawrence Steinman; Paul J Utz; William H Robinson
Suppression of autoimmunity via microbial mimics of altered peptide ligands.
Current topics in microbiology and immunology 2005;296():55-63.
2004: Steven M Chan; Joerg Ermann; Leon Su; C Garrison Fathman; Paul J Utz
Protein microarrays for multiplex analysis of signal transduction pathways.
Nature medicine 2004;10(12):1390-6.
2004: Leon Su; Rémi J Creusot; Elena M Gallo; Steven M Chan; Paul J Utz; C Garrison Fathman; Joerg Ermann
Murine CD4+CD25+ regulatory T cells fail to undergo chromatin remodeling across the proximal promoter region of the IL-2 gene.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):4994-5001.
2004: Wolfgang Hueber; Defu Zeng; Samuel Strober; Paul J Utz
Interferon-alpha-inducible proteins are novel autoantigens in murine lupus.
Arthritis and rheumatism 2004;50(10):3239-49.
2004: Kareem L Graham; William H Robinson; Lawrence Steinman; Paul J Utz
High-throughput methods for measuring autoantibodies in systemic lupus erythematosus and other autoimmune diseases.
Autoimmunity 2004;37(4):269-72.
2004: Kareem L Graham; Kurt E. Gustin; Carlos Rivera; N Muge Kuyumcu-Martinez; Sunny S Choe; Richard E Lloyd; Peter Sarnow; Paul J Utz
Proteolytic cleavage of the catalytic subunit of DNA-dependent protein kinase during poliovirus infection.
Journal of virology 2004;78(12):6313-21.
2004: Wolfgang Hueber; Defu Zeng; Orr Sharpe; William H Robinson; Samuel Strober; Paul J Utz
Characterization of novel antigens recognized by serum autoantibodies from anti-CD1 TCR-transgenic lupus mice.
European journal of immunology 2004;34(6):1654-62.
2004: Paul J Utz
"Hot technologies" for clinical immunology research.
Clinical immunology (Orlando, Fla.) 2004;111(2):153-4.
2004: Paul J Utz; Mark C Genovese; William H Robinson
Unlocking the "PAD" lock on rheumatoid arthritis.
Annals of the rheumatic diseases 2004;63(4):330-2.
2004: Lorinda Chung; Paul J Utz
Antibodies in scleroderma: direct pathogenicity and phenotypic associations.
Current rheumatology reports 2004;6(2):156-63.
2003: William H Robinson; Paul J Utz; Lawrence Steinman
Genomic and proteomic analysis of multiple sclerosis. Opinion.
Current opinion in immunology 2003;15(6):660-7.
2003: William H Robinson; Lawrence Steinman; Paul J Utz
Protein arrays for autoantibody profiling and fine-specificity mapping.
Proteomics 2003;3(11):2077-84.
2003: Henry Neuman de Vegvar; Rama Rao Amara; Lawrence Steinman; Paul J Utz; Harriet L Robinson; William H Robinson
Microarray profiling of antibody responses against simian-human immunodeficiency virus: postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen.
Journal of virology 2003;77(20):11125-38.
2003: Wolfgang Hueber; Paul J Utz; William H Robinson
Autoantibodies in early arthritis: advances in diagnosis and prognostication.
Clinical and experimental rheumatology 2003;21(5 Suppl 31):S59-64.
2003: William H Robinson; Paulo Fontoura; Byung J Lee; Henry Neuman de Vegvar; Jennifer Tom; Rosetta Pedotti; Carla DiGennaro; Dennis J Mitchell; Derek Fong; Peggy P Ho; Pedro J Ruiz; Emanual Maverakis; David B Stevens; Claude C A Bernard; Roland Martin; Vijay K Kuchroo; Johannes M van Noort; Claude P Genain; Sandra Amor; Tomas Olsson; Paul J Utz; Hideki Garren; Lawrence Steinman
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis.
Nature biotechnology 2003;21(9):1033-9.
2003: Robert J Chen; Sarunya Bangsaruntip; Katerina A Drouvalakis; Nadine Wong Shi Kam; Moonsub Shim; Yiming Li; Woong Kim; Paul J Utz; Hongjie Dai
Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):4984-9.
2003: Amy E Herr; Joshua I Molho; Katerina A Drouvalakis; James C Mikkelsen; Paul J Utz; Juan G Santiago; Thomas W Kenny
On-chip coupling of isoelectric focusing and free solution electrophoresis for multidimensional separations.
Analytical chemistry 2003;75(5):1180-7.
2003: Donna L Thibault; Paul J Utz
Interpreting interest in interferon-alpha.
Arthritis research & therapy 2003;5(5):246-8.
2002: William H Robinson; Lawrence Steinman; Paul J Utz
Protein and peptide array analysis of autoimmune disease.
BioTechniques 2002;Suppl():66-9.
2002: Makoto Kamachi; Truc M Le; Susan J Kim; Meghan E Geiger; Paul Anderson; Paul J Utz
Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway.
The Journal of experimental medicine 2002;196(9):1213-25.
2002: William H Robinson; Hideki Garren; Paul J Utz; Lawrence Steinman
Millennium Award. Proteomics for the development of DNA tolerizing vaccines to treat autoimmune disease.
Clinical immunology (Orlando, Fla.) 2002;103(1):7-12.
2002: William H Robinson; Lawrence Steinman; Paul J Utz
Proteomics technologies for the study of autoimmune disease.
Arthritis and rheumatism 2002;46(4):885-93.
2002: William H Robinson; Carla DiGennaro; Wolfgang Hueber; Brian B Haab; Makoto Kamachi; Erik J Dean; Sylvie Fournel; Derek Fong; Mark C Genovese; Henry Neuman de Vegvar; Karl Skriner; David L Hirschberg; Robert I Morris; Sylviane Muller; Ger J Pruijn; Walther J van Venrooij; Josef S Smolen; Patrick O Brown; Lawrence Steinman; Paul J Utz
Autoantigen microarrays for multiplex characterization of autoantibody responses.
Nature medicine 2002;8(3):295-301.
2002: Wolfgang Hueber; Paul J Utz; Lawrence Steinman; William H Robinson
Autoantibody profiling for the study and treatment of autoimmune disease.
Arthritis research 2002;4(5):290-5.
2001: TJ Gensler; M Hottelet; C Zhang; S Schlossman; Paul Anderson; Paul J Utz
Monoclonal antibodies derived from BALB/c mice immunized with apoptotic Jurkat T cells recognize known autoantigens.
Journal of autoimmunity 2001;16(1):59-69.
2001: Paul J Utz
21st European Workshop for Rheumatology Research, Vienna, Austria, 1-4 March 2001.
Arthritis research 2001;3(4):237-40.
2000: Karin Pike-Overzet; TJ Gensler; S J Kim; M E Geiger; W J van Venrooij; K M Pollard; Paul Anderson; Paul J Utz
Small nucleolar RNP scleroderma autoantigens associate with phosphorylated serine/arginine splicing factors during apoptosis.
Arthritis and rheumatism 2000;43(6):1327-36.
2000: Paul J Utz; TJ Gensler; P Anderson
Death, autoantigen modifications, and tolerance.
Arthritis research 2000;2(2):101-14.
1998: Paul J Utz; M Hottelet; T M Le; S J Kim; M E Geiger; W J van Venrooij; Paul Anderson
The 72-kDa component of signal recognition particle is cleaved during apoptosis.
The Journal of biological chemistry 1998;273(52):35362-70.
1998: Paul J Utz; M Hottelet; W J van Venrooij; Paul Anderson
Association of phosphorylated serine/arginine (SR) splicing factors with the U1-small ribonucleoprotein (snRNP) autoantigen complex accompanies apoptotic cell death.
The Journal of experimental medicine 1998;187(4):547-60.
1997: Paul J Utz; M Hottelet; P H Schur; Paul Anderson
Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus.
The Journal of experimental medicine 1997;185(5):843-54.