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Rudolf Valenta
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133
Kraft, Dietrich
84
Valent, Peter
69
Vrtala, Susanne
66
Spitzauer, Susanne
38
Sperr, Wolfgang
38
Scheiner, Otto
36
Ebner, Christof
35
Niederberger, Verena
30
Laffer, Sylvia
28
Grote, Monika
23
Ball, Tanja
23
Rumpold, Helmut
23
Steinberger, Peter
23
Swoboda, Ines
20
Pauli, Gabrielle
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All Publications
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2009: Constantin C; Quirce S; Poorafshar M; Touraev A; Niggemann B; Mari A; Ebner C; Akerström H; Heberle-Bors E; Nystrand M; Valenta R
Micro-arrayed wheat seed and grass pollen allergens for component-resolved diagnosis.
Allergy 2009;64(7):1030-7.
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2009: Schulmeister Ulrike; Hochwallner Heidrun; Swoboda Ines; Focke-Tejkl Margarete; Geller Beate; Nystrand Mats; Härlin Annika; Thalhamer Josef; Scheiblhofer Sandra; Keller Walter; Niggemann Bodo; Quirce Santiago; Ebner Christoph; Mari Adriano; Pauli Gabrielle; Herz Udo; Valenta Rudolf; Spitzauer Susanne
Cloning, expression, and mapping of allergenic determinants of alphaS1-casein, a major cow's milk allergen.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):7019-29.
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2009: Pree Ines; Reisinger Jürgen; Bohle Barbara; Frantal Sophie; Valenta Rudolf; Niederberger Verena
A sensitive assay for the detection of IgE bound to the major birch pollen allergen, Bet v 1, in the form of immune complexes.
Journal of immunological methods 2009;345(1-2):100-5.
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2009: Edlmayr Johanna; Niespodziana Katarzyna; Linhart Birgit; Focke-Tejkl Margarete; Westritschnig Kerstin; Scheiblhofer Sandra; Stoecklinger Angelika; Kneidinger Michael; Valent Peter; Campana Raffaela; Thalhamer Josef; Popow-Kraupp Theresia; Valenta Rudolf
A combination vaccine for allergy and rhinovirus infections based on rhinovirus-derived surface protein VP1 and a nonallergenic peptide of the major timothy grass pollen allergen Phl p 1.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6298-306.
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2009: Focke M; Marth K; Valenta R
Molecular composition and biological activity of commercial birch pollen allergen extracts.
European journal of clinical investigation 2009;39(5):429-36.
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2009: Lupinek Christian; Roux Kenneth H; Laffer Sylvia; Rauter Ingrid; Reginald Kavita; Kneidinger Michael; Blatt Katharina; Ball Tanja; Pree Ines; Jahn-Schmid Beatrice; Allam Jean-Pierre; Novak Natalija; Drescher Anja; Kricek Franz; Valent Peter; Englund Hakan; Valenta Rudolf
Trimolecular complex formation of IgE, Fc(epsilon)RI, and a recombinant nonanaphylactic single-chain antibody fragment with high affinity for IgE.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4817-29.
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2009: Ball T; Linhart B; Sonneck K; Blatt K; Herrmann H; Valent P; Stoecklinger A; Lupinek C; Thalhamer J; Fedorov A A; Almo S C; Valenta R
Reducing allergenicity by altering allergen fold: a mosaic protein of Phl p 1 for allergy vaccination.
Allergy 2009;64(4):569-80.
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2009: Valenta Rudolf; Mittermann Irene; Werfel Thomas; Garn Holger; Renz Harald
Linking allergy to autoimmune disease.
Trends in immunology 2009;30(3):109-16.
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2009: Gangl K; Reininger R; Bernhard D; Campana R; Pree I; Reisinger J; Kneidinger M; Kundi M; Dolznig H; Thurnher D; Valent P; Chen K-W; Vrtala S; Spitzauer S; Valenta R; Niederberger V
Cigarette smoke facilitates allergen penetration across respiratory epithelium.
Allergy 2009;64(3):398-405.
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2009: Padavattan Sivaraman; Flicker Sabine; Schirmer Tilman; Madritsch Christoph; Randow Stefanie; Reese Gerald; Vieths Stefan; Lupinek Christian; Ebner Christof; Valenta Rudolf; Markovic-Housley Zora
High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2141-51.
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2009: Constantin Claudia; Touraev Alisher; Heberle-Bors Erwin; Quirce Santiago; Huber Wolf Dietrich; Valenta Rudolf
Detection of antigens reactive to IgE and IgA during wheat seed maturation and in different wheat cultivars.
International archives of allergy and immunology 2009;149(3):181-7.
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2008: Weghofer M; Thomas W R; Kronqvist M; Mari A; Purohit A; Pauli G; Horak F; Grönlund H; van Hage M; Valenta R; Vrtala S
Variability of IgE reactivity profiles among European mite allergic patients.
European journal of clinical investigation 2008;38(12):959-65.
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2008: Mothes-Luksch Nadine; Stumvoll Sabine; Linhart Birgit; Focke Margit; Krauth Marie-Therese; Hauswirth Alexander; Valent Peter; Verdino Petra; Pavkov Tea; Keller Walter; Grote Monika; Valenta Rudolf
Disruption of allergenic activity of the major grass pollen allergen Phl p 2 by reassembly as a mosaic protein.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4864-73.
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2008: Egger C; Focke M; Bircher A J; Scherer K; Mothes-Luksch N; Horak F; Valenta R
The allergen profile of beech and oak pollen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(10):1688-96.
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2008: Purohit A; Niederberger V; Kronqvist M; Horak F; Grönneberg R; Suck R; Weber B; Fiebig H; van Hage M; Pauli G; Valenta R; Cromwell O
Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(9):1514-25.
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2008: Altrichter Sabine; Kriehuber Ernst; Moser Julia; Valenta Rudolf; Kopp Tamara; Stingl Georg
Serum IgE autoantibodies target keratinocytes in patients with atopic dermatitis.
The Journal of investigative dermatology 2008;128(9):2232-9.
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2008: Focke M; Marth K; Flicker S; Valenta R
Heterogeneity of commercial timothy grass pollen extracts.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(8):1400-8.
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2008: Grönlund H; Adédoyin J; Reininger R; Varga E-M; Zach M; Fredriksson M; Kronqvist M; Szepfalusi Z; Spitzauer S; Grönneberg R; Valenta R; Hedlin G; van Hage M
Higher immunoglobulin E antibody levels to recombinant Fel d 1 in cat-allergic children with asthma compared with rhinoconjunctivitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(8):1275-81.
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2008: Linhart Birgit; Mothes-Luksch Nadine; Vrtala Susanne; Kneidinger Michael; Valent Peter; Valenta Rudolf
A hypoallergenic hybrid molecule with increased immunogenicity consisting of derivatives of the major grass pollen allergens, Phl p 2 and Phl p 6.
Biological chemistry 2008;389(7):925-33.
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2008: Baranyi Ulrike; Linhart Birgit; Pilat Nina; Gattringer Martina; Bagley Jessamyn; Muehlbacher Ferdinand; Iacomini John; Valenta Rudolf; Wekerle Thomas
Tolerization of a type I allergic immune response through transplantation of genetically modified hematopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8168-75.
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2008: Constantin Claudia; Quirce Santiago; Grote Monika; Touraev Alisher; Swoboda Ines; Stoecklinger Angelika; Mari Adriano; Thalhamer Josef; Heberle-Bors Erwin; Valenta Rudolf
Molecular and immunological characterization of a wheat serine proteinase inhibitor as a novel allergen in baker's asthma.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7451-60.
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2008: Weghofer M; Dall'Antonia Y; Grote M; Stöcklinger A; Kneidinger M; Balic N; Krauth M-T; Fernández-Caldas E; Thomas W R; van Hage M; Vieths S; Spitzauer S; Horak F; Svergun D I; Konarev P V; Valent P; Thalhamer J; Keller W; Valenta R; Vrtala S
Characterization of Der p 21, a new important allergen derived from the gut of house dust mites.
Allergy 2008;63(6):758-67.
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2008: Laffer S; Lupinek C; Rauter I; Kneidinger M; Drescher A; Jordan J-H; Krauth M-T; Valent P; Kricek F; Spitzauer S; Englund H; Valenta R
A high-affinity monoclonal anti-IgE antibody for depletion of IgE and IgE-bearing cells.
Allergy 2008;63(6):695-702.
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2008: Mittermann Irene; Reininger Renate; Zimmermann Maya; Gangl Katharina; Reisinger Jürgen; Aichberger Karl J; Greisenegger Elli K; Niederberger Verena; Seipelt Joachim; Bohle Barbara; Kopp Tamara; Akdis Cezmi A; Spitzauer Susanne; Valent Peter; Valenta Rudolf
The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma.
The Journal of investigative dermatology 2008;128(6):1451-9.
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2008: Chen Kuan-Wei; Fuchs Gudrun; Sonneck Karoline; Gieras Anna; Swoboda Ines; Douladiris Nikolas; Linhart Birgit; Jankovic Marija; Pavkov Tea; Keller Walter; Papadopoulos Nikolaos G; Valent Peter; Valenta Rudolf; Vrtala Susanne
Reduction of the in vivo allergenicity of Der p 2, the major house-dust mite allergen, by genetic engineering.
Molecular immunology 2008;45(9):2486-98.
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2008: Persson Helena; Flicker Sabine; Sadegh Mardjaneh Karbalaei; Greiff Lennart; Valenta Rudolf; Ohlin Mats
A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2.
Molecular immunology 2008;45(9):2715-20.
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2008: Westritschnig K; Horak F; Swoboda I; Balic N; Spitzauer S; Kundi M; Fiebig H; Suck R; Cromwell O; Valenta R
Different allergenic activity of grass pollen allergens revealed by skin testing.
European journal of clinical investigation 2008;38(4):260-7.
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2008: Kneidinger Michael; Schmidt Uwe; Rix Uwe; Gleixner Karoline V; Vales Anja; Baumgartner Christian; Lupinek Christian; Weghofer Margit; Bennett Keiryn L; Herrmann Harald; Schebesta Alexandra; Thomas Wayne R; Vrtala Susanne; Valenta Rudolf; Lee Francis Y; Ellmeier Wilfried; Superti-Furga Giulio; Valent Peter
The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils.
Blood 2008;111(6):3097-107.
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2008: Campana Raffaela; Mothes Nadine; Rauter Ingrid; Vrtala Susanne; Reininger Renate; Focke-Tejkl Margarete; Lupinek Christian; Balic Nadja; Spitzauer Susanne; Valenta Rudolf
Non-IgE-mediated chronic allergic skin inflammation revealed with rBet v 1 fragments.
The Journal of allergy and clinical immunology 2008;121(2):528-530.e1.
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2008: Verdino Petra; Barderas Rodrigo; Villalba Mayte; Westritschnig Kerstin; Valenta Rudolf; Rodriguez Rosalia; Keller Walter
Three-dimensional structure of the cross-reactive pollen allergen Che a 3: visualizing cross-reactivity on the molecular surfaces of weed, grass, and tree pollen allergens.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2313-21.
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2008: Flicker S; Steinberger P; Eibensteiner P B; Lebecque S; Kraft D; Valenta R
Molecular characterization of a human immunoglobulin G4 antibody specific for the major birch pollen allergen, Bet v 1.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(2):365-73.
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2008: Sonneck K; Baumgartner C; Rebuzzi L; Marth K; Chen K W; Hauswirth A W; Florian S; Vrtala S; Bühring H J; Valenta R; Valent P
Recombinant allergens promote expression of aminopeptidase-n (CD13) on basophils in allergic patients.
International journal of immunopathology and pharmacology 2008;21(1):11-21.
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2008: Schulmeister U; Swoboda I; Quirce S; de la Hoz B; Ollert M; Pauli G; Valenta R; Spitzauer S
Sensitization to human milk.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(1):60-8.
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2008: Rauter Ingrid; Krauth Maria-Theresa; Westritschnig Kerstin; Horak Friedrich; Flicker Sabine; Gieras Anna; Repa Andreas; Balic Nadja; Spitzauer Susanne; Huss-Marp Johannes; Brockow Knut; Darsow Ulf; Behrendt Heidrun; Ring Johannes; Kricek Franz; Valent Peter; Valenta Rudolf
Mast cell-derived proteases control allergic inflammation through cleavage of IgE.
The Journal of allergy and clinical immunology 2008;121(1):197-202.
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2008: Swoboda Ines; Twaroch Teresa; Valenta Rudolf; Grote Monika
Tree pollen allergens.
Clinical allergy and immunology 2008;21():87-105.
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2008: Weghofer Margit; Grote Monika; Dall'Antonia Yuliya; Fernández-Caldas Enrique; Krauth Maria-Theresa; van Hage Marianne; Horak Friedrich; Thomas Wayne R; Valent Peter; Keller Walter; Valenta Rudolf; Vrtala Susanne
Characterization of folded recombinant Der p 5, a potential diagnostic marker allergen for house dust mite allergy.
International archives of allergy and immunology 2008;147(2):101-9.
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2008: Grote Monika; Westritschnig Kerstin; Valenta Rudolf
Immunogold electron microscopic localization of the 2 EF-hand calcium-binding pollen allergen Phl p 7 and its homologues in pollens of grasses, weeds and trees.
International archives of allergy and immunology 2008;146(2):113-21.
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2007: Westritschnig Kerstin; Linhart Birgit; Focke-Tejkl Margarete; Pavkov Tea; Keller Walter; Ball Tanja; Mari Adriano; Hartl Arnulf; Stöcklinger Angelika; Scheiblhofer Sandra; Thalhamer Josef; Ferreira Fatima; Vieths Stefan; Vogel Lothar; Böhm Alexandra; Valent Peter; Valenta Rudolf
A hypoallergenic vaccine obtained by tail-to-head restructuring of timothy grass pollen profilin, Phl p 12, for the treatment of cross-sensitization to profilin.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7624-34.
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2007: Admyre Charlotte; Bohle Barbara; Johansson Sara M; Focke-Tejkl Margarete; Valenta Rudolf; Scheynius Annika; Gabrielsson Susanne
B cell-derived exosomes can present allergen peptides and activate allergen-specific T cells to proliferate and produce TH2-like cytokines.
The Journal of allergy and clinical immunology 2007;120(6):1418-24.
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2007: Pree Ines; Reisinger Jürgen; Focke Margit; Vrtala Susanne; Pauli Gabrielle; van Hage Marianne; Cromwell Oliver; Gadermaier Elisabeth; Egger Cornelia; Reider Norbert; Horak Friedrich; Valenta Rudolf; Niederberger Verena
Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5309-16.
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2007: Bussmann C; Maintz L; Hart J; Allam J-P; Vrtala S; Chen K-W; Bieber T; Thomas W R; Valenta R; Zuberbier T; Sager A; Novak N
Clinical improvement and immunological changes in atopic dermatitis patients undergoing subcutaneous immunotherapy with a house dust mite allergoid: a pilot study.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(9):1277-85.
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2007: Vrtala Susanne; Focke Margarete; Kopec Jolanta; Verdino Petra; Hartl Arnulf; Sperr Wolfgang R; Fedorov Alexander A; Ball Tanja; Almo Steve; Valent Peter; Thalhamer Josef; Keller Walter; Valenta Rudolf
Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1730-9.
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2007: Metz-Favre Carine; Linhart Birgit; Focke-Tejkl Margarete; Purohit Ashok; de Blay Frédéric; Valenta Rudolf; Pauli Gabrielle
Skin test diagnosis of grass pollen allergy with a recombinant hybrid molecule.
The Journal of allergy and clinical immunology 2007;120(2):315-21.
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2007: Swoboda Ines; Bugajska-Schretter Agnes; Linhart Birgit; Verdino Petra; Keller Walter; Schulmeister Ulrike; Sperr Wolfgang R; Valent Peter; Peltre Gabriel; Quirce Santiago; Douladiris Nikolaos; Papadopoulos Nikolaos G; Valenta Rudolf; Spitzauer Susanne
A recombinant hypoallergenic parvalbumin mutant for immunotherapy of IgE-mediated fish allergy.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6290-6.
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2007: Padavattan Sivaraman; Schirmer Tilman; Schmidt Margit; Akdis Cezmi; Valenta Rudolf; Mittermann Irene; Soldatova Lyudmila; Slater Jay; Mueller Ulrich; Markovic-Housley Zora
Identification of a B-cell epitope of hyaluronidase, a major bee venom allergen, from its crystal structure in complex with a specific Fab.
Journal of molecular biology 2007;368(3):742-52.
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2007: Hauswirth A W; Sonneck K; Florian S; Krauth M T; Bohm A; Sperr W R; Valenta R; Schernthaner G H; Printz D; Fritsch G; Buhring H J; Valent P
Interleukin-3 promotes the expression of E-NPP3/CD203C on human blood basophils in healthy subjects and in patients with birch pollen allergy.
International journal of immunopathology and pharmacology 2007;20(2):267-78.
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2007: Valenta Rudolf; Niederberger Verena
Recombinant allergens for immunotherapy.
The Journal of allergy and clinical immunology 2007;119(4):826-30.
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2007: Niederberger Verena; Reisinger Jürgen; Valent Peter; Krauth Maria-Theresa; Pauli Gabrielle; van Hage Marianne; Cromwell Oliver; Horak Friedrich; Valenta Rudolf
Vaccination with genetically modified birch pollen allergens: immune and clinical effects on oral allergy syndrome.
The Journal of allergy and clinical immunology 2007;119(4):1013-6.
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2007: Linhart Birgit; Bigenzahn Sinda; Hartl Arnulf; Lupinek Christian; Thalhamer Josef; Valenta Rudolf; Wekerle Thomas
Costimulation blockade inhibits allergic sensitization but does not affect established allergy in a murine model of grass pollen allergy.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3924-31.
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2007: Gieras Anna; Focke-Tejkl Margarete; Ball Tanja; Verdino Petra; Hartl Arnulf; Thalhamer Josef; Valenta Rudolf
Molecular determinants of allergen-induced effector cell degranulation.
The Journal of allergy and clinical immunology 2007;119(2):384-90.
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2007: Stern Debra A; Riedler Josef; Nowak Dennis; Braun-Fahrlander Charlotte; Swoboda Ines; Balic Nadja; Chen Kuan-Wei; Vrtala Susanne; Grönlund Hans; van Hage Marianne; Valenta Rudolf; Spitzauer Susanne; Von Mutius Erika; Vercelli Donata
Exposure to a farming environment has allergen-specific protective effects on TH2-dependent isotype switching in response to common inhalants.
The Journal of allergy and clinical immunology 2007;119(2):351-8.
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2007: Reininger R; Varga E M; Zach M; Balic N; Lindemeier A D; Swoboda I; Grönlund H; van Hage M; Rumpold H; Valenta R; Spitzauer S
Detection of an allergen in dog dander that cross-reacts with the major cat allergen, Fel d 1.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(1):116-24.
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2007: Niederberger Verena; Ring Johannes; Rakoski Jürgen; Jager Siegfried; Spitzauer Susanne; Valent Peter; Horak Friedrich; Kundi Michael; Valenta Rudolf
Antigens drive memory IgE responses in human allergy via the nasal mucosa.
International archives of allergy and immunology 2007;142(2):133-44.
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2006: Flicker Sabine; Steinberger Peter; Ball Tanja; Krauth Maria-Theresa; Verdino Petra; Valent Peter; Almo Steve; Valenta Rudolf
Spatial clustering of the IgE epitopes on the major timothy grass pollen allergen Phl p 1: importance for allergenic activity.
The Journal of allergy and clinical immunology 2006;117(6):1336-43.
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2006: Rauter Ingrid; Krauth Maria-Theresa; Flicker Sabine; Gieras Anna; Westritschnig Kerstin; Vrtala Susanne; Balic Nadja; Spitzauer Susanne; Huss-Marp Johannes; Brockow Knut; Darsow Ulf; Ring Johannes; Behrendt Heidrun; Semper Hans; Valent Peter; Valenta Rudolf
Allergen cleavage by effector cell-derived proteases regulates allergic inflammation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):967-9.
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2006: Ledesma A; Barderas R; Westritschnig K; Quiralte J; Pascual C Y; Valenta R; Villalba M; Rodríguez R
A comparative analysis of the cross-reactivity in the polcalcin family including Syr v 3, a new member from lilac pollen.
Allergy 2006;61(4):477-84.
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2006: Niederberger Verena; Valenta Rudolf
Molecular approaches for new vaccines against allergy.
Expert review of vaccines 2006;5(1):103-10.
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2006: Winkler B; Hufnagl K; Spittler A; Ploder M; Kállay E; Vrtala S; Valenta R; Kundi M; Renz H; Wiedermann U
The role of Foxp3+ T cells in long-term efficacy of prophylactic and therapeutic mucosal tolerance induction in mice.
Allergy 2006;61(2):173-80.
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2006: Palomares Oscar; Swoboda Ines; Villalba Mayte; Balic Nadia; Spitzauer Susanne; Rodríguez Rosalía; Valenta Rudolf
The major allergen of olive pollen Ole e 1 is a diagnostic marker for sensitization to Oleaceae.
International archives of allergy and immunology 2006;141(2):110-8.
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2006: Mothes Nadine; Valenta Rudolf; Spitzauer Susanne
Allergy testing: the role of recombinant allergens.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2006;44(2):125-32.
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2005: Linhart Birgit; Valenta Rudolf
Molecular design of allergy vaccines.
Current opinion in immunology 2005;17(6):646-55.
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2005: Constantin Claudia; Huber Wolf Dietrich; Granditsch Gerhard; Weghofer Margit; Valenta Rudolf
Different profiles of wheat antigens are recognised by patients suffering from coeliac disease and IgE-mediated food allergy.
International archives of allergy and immunology 2005;138(3):257-66.
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2005: Weghofer M; Thomas W R; Pittner G; Horak F; Valenta R; Vrtala S
Comparison of purified Dermatophagoides pteronyssinus allergens and extract by two-dimensional immunoblotting and quantitative immunoglobulin E inhibitions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(10):1384-91.
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2005: Mothes Nadine; Niggemann Bodo; Jenneck Claudia; Hagemann Tobias; Weidinger Stephan; Bieber Thomas; Valenta Rudolf; Novak Natalija
The cradle of IgE autoreactivity in atopic eczema lies in early infancy.
The Journal of allergy and clinical immunology 2005;116(3):706-9.
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2005: Gafvelin Guro; Thunberg Sarah; Kronqvist Marianne; Grönlund Hans; Grönneberg Reidar; Troye-Blomberg Marita; Akdis Mübeccel; Fiebig Helmut; Purohit Ashok; Horak Friedrich; Reisinger Jürgen; Niederberger Verena; Akdis Cezmi A; Cromwell Oliver; Pauli Gabrielle; Valenta Rudolf; van Hage Marianne
Cytokine and antibody responses in birch-pollen-allergic patients treated with genetically modified derivatives of the major birch pollen allergen Bet v 1.
International archives of allergy and immunology 2005;138(1):59-66.
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2005: Hufnagl Karin; Winkler Birgit; Focke Margit; Valenta Rudolf; Scheiner Otto; Renz Harald; Wiedermann Ursula
Intranasal tolerance induction with polypeptides derived from 3 noncross-reactive major aeroallergens prevents allergic polysensitization in mice.
The Journal of allergy and clinical immunology 2005;116(2):370-6.
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2005: Reisinger Jürgen; Horak Friedrich; Pauli Gabrielle; van Hage Marianne; Cromwell Oliver; König Franz; Valenta Rudolf; Niederberger Verena
Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivity.
The Journal of allergy and clinical immunology 2005;116(2):347-54.
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2005: Aichberger Karl J; Mittermann Irene; Reininger Renate; Seiberler Susanne; Swoboda Ines; Spitzauer Susanne; Kopp Tamara; Stingl Georg; Sperr Wolfgang R; Valent Peter; Repa Andreas; Bohle Barbara; Kraft Dietrich; Valenta Rudolf
Hom s 4, an IgE-reactive autoantigen belonging to a new subfamily of calcium-binding proteins, can induce Th cell type 1-mediated autoreactivity.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):1286-94.
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2005: Mittermann Irene; Voronin Viktor; Heberle-Bors Erwin; Valenta Rudolf
Identification of a villin-related tobacco protein as a novel cross-reactive plant allergen.
FEBS letters 2005;579(17):3807-13.
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2005: Sellge G; Laffer S; Mierke C; Vrtala S; Hoffmann M W; Klempnauer J; Manns M P; Valenta R; Bischoff S C
Development of an in vitro system for the study of allergens and allergen-specific immunoglobulin E and immunoglobulin G: Fcepsilon receptor I supercross-linking is a possible new mechanism of immunoglobulin G-dependent enhancement of type I allergic reactions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(6):774-81.
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2005: Linhart Birgit; Hartl Arnulf; Jahn-Schmid Beatrice; Verdino Petra; Keller Walter; Krauth Maria-Theresa; Valent Peter; Horak Friedrich; Wiedermann Ursula; Thalhamer Josef; Ebner Christof; Kraft Dietrich; Valenta Rudolf
A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination.
The Journal of allergy and clinical immunology 2005;115(5):1010-6.
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2005: Reisinger Jürgen; Triendl Andrea; Küchler Ernst; Bohle Barbara; Krauth Maria Theresa; Rauter Ingrid; Valent Peter; Koenig Franz; Valenta Rudolf; Niederberger Verena
IFN-gamma-enhanced allergen penetration across respiratory epithelium augments allergic inflammation.
The Journal of allergy and clinical immunology 2005;115(5):973-81.
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2005: Grote Monika; Swoboda Ines; Valenta Rudolf; Reichelt Rudolf
Group 13 allergens as environmental and immunological markers for grass pollen allergy: studies by immunogold field emission scanning and transmission electron microscopy.
International archives of allergy and immunology 2005;136(4):303-10.
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2005: Batard Thierry; Didierlaurent Alain; Chabre Henri; Mothes Nadine; Bussières Laetitia; Bohle Barbara; Couret Marie-Noëlle; Ball Tanja; Lemoine Pierrick; Focks Tejkl Margarete; Chenal Alexandre; Clément Gilles; Dupont Francis; Valent Peter; Krauth Marie-Theres; André Claude; Valenta Rudolf; Moingeon Philippe
Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy.
International archives of allergy and immunology 2005;136(3):239-49.
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2005: Purohit A; Laffer S; Metz-Favre C; Verot A; Kricek F; Valenta R; Pauli G
Poor association between allergen-specific serum immunoglobulin E levels, skin sensitivity and basophil degranulation: a study with recombinant birch pollen allergen Bet v 1 and an immunoglobulin E detection system measuring immunoglobulin E capable of binding to Fc epsilon RI.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(2):186-92.
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2005: Ball Tanja; Edstrom William; Mauch Ludwig; Schmitt Jacky; Leistler Bernd; Fiebig Helmut; Sperr Wolfgang R; Hauswirth Alexander W; Valent Peter; Kraft Dietrich; Almo Steven C; Valenta Rudolf
Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1.
The FEBS journal 2005;272(1):217-27.
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2004: Niederberger Verena; Valenta Rudolf
Recombinant allergens for immunotherapy. Where do we stand?
Current opinion in allergy and clinical immunology 2004;4(6):549-54.
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2004: Mothes Nadine; Horak Friedrich; Valenta Rudolf
Transition from a botanical to a molecular classification in tree pollen allergy: implications for diagnosis and therapy.
International archives of allergy and immunology 2004;135(4):357-73.
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2004: Hantusch Brigitte; Krieger Sigurd; Untersmayr Eva; Schöll Isabella; Knittelfelder Regina; Flicker Sabine; Spitzauer Susanne; Valenta Rudolf; Boltz-Nitulescu George; Scheiner Otto; Jensen-Jarolim Erika
Mapping of conformational IgE epitopes on Phl p 5a by using mimotopes from a phage display library.
The Journal of allergy and clinical immunology 2004;114(6):1294-300.
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2004: Niederberger Verena; Valenta Rudolf
Genetically modified allergens.
Immunology and allergy clinics of North America 2004;24(4):727-38.
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2004: Limmongkon Apinun; Giuliani Concetta; Valenta Rudolf; Mittermann Irene; Heberle-Bors Erwin; Wilson Cathal
MAP kinase phosphorylation of plant profilin.
Biochemical and biophysical research communications 2004;324(1):382-6.
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2004: Focke M; Linhart B; Hartl A; Wiedermann U; Sperr W R; Valent P; Thalhamer J; Kraft D; Valenta R
Non-anaphylactic surface-exposed peptides of the major birch pollen allergen, Bet v 1, for preventive vaccination.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(10):1525-33.
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2004: Mittermann Irene; Aichberger Karl J; Bünder Robert; Mothes Nadine; Renz Harald; Valenta Rudolf
Autoimmunity and atopic dermatitis.
Current opinion in allergy and clinical immunology 2004;4(5):367-71.
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2004: Niederberger V; Horak F; Vrtala S; Spitzauer S; Krauth M-T; Valent P; Reisinger J; Pelzmann M; Hayek B; Kronqvist M; Gafvelin G; Grönlund H; Purohit A; Suck R; Fiebig H; Cromwell O; Pauli G; van Hage-Hamsten M; Valenta R
Vaccination with genetically engineered allergens prevents progression of allergic disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101 Suppl 2():14677-82.
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2004: Mothes Nadine; Valenta Rudolf
Biology of tree pollen allergens.
Current allergy and asthma reports 2004;4(5):384-90.
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2004: Bünder Robert; Mittermann Irene; Herz Udo; Focke Margit; Wegmann Michael; Valenta Rudolf; Renz Harald
Induction of autoallergy with an environmental allergen mimicking a self protein in a murine model of experimental allergic asthma.
The Journal of allergy and clinical immunology 2004;114(2):422-8.
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2004: Novak Natalija; Allam Jean-Pierre; Hagemann Tobias; Jenneck Claudia; Laffer Sylvia; Valenta Rudolf; Kochan Jarema; Bieber Thomas
Characterization of FcepsilonRI-bearing CD123 blood dendritic cell antigen-2 plasmacytoid dendritic cells in atopic dermatitis.
The Journal of allergy and clinical immunology 2004;114(2):364-70.
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2004: Linhart Birgit; Valenta Rudolf
Vaccine engineering improved by hybrid technology.
International archives of allergy and immunology 2004;134(4):324-31.
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2004: Akdis Mübeccel; Verhagen Johan; Taylor Alison; Karamloo Fariba; Karagiannidis Christian; Crameri Reto; Thunberg Sarah; Deniz Günnur; Valenta Rudolf; Fiebig Helmut; Kegel Christian; Disch Rainer; Schmidt-Weber Carsten B; Blaser Kurt; Akdis Cezmi A
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells.
The Journal of experimental medicine 2004;199(11):1567-75.
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2004: Novak Natalija; Valenta Rudolf; Bohle Barbara; Laffer Sylvia; Haberstok Jörg; Kraft Stefan; Bieber Thomas
FcepsilonRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro.
The Journal of allergy and clinical immunology 2004;113(5):949-57.
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2004: Swoboda Ines; Grote Monika; Verdino Petra; Keller Walter; Singh Mohan B; De Weerd Nicole; Sperr Wolfgang R; Valent Peter; Balic Nadja; Reichelt Rudolf; Suck Roland; Fiebig Helmut; Valenta Rudolf; Spitzauer Susanne
Molecular characterization of polygalacturonases as grass pollen-specific marker allergens: expulsion from pollen via submicronic respirable particles.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6490-500.
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2004: Westritschnig Kerstin; Focke Margarete; Verdino Petra; Goessler Walter; Keller Walter; Twardosz Anna; Mari Adriano; Horak Friedrich; Wiedermann Ursula; Hartl Arnulf; Thalhamer Josef; Sperr Wolfgang R; Valent Peter; Valenta Rudolf
Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p 7.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5684-92.
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2004: Pittner G; Vrtala S; Thomas W R; Weghofer M; Kundi M; Horak F; Kraft D; Valenta R
Component-resolved diagnosis of house-dust mite allergy with purified natural and recombinant mite allergens.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(4):597-603.
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2004: Marth Katharina; Focke Margarete; Flicker Sabine; Valenta Rudolf
Human monoclonal antibody-based quantification of group 2 grass pollen allergens.
The Journal of allergy and clinical immunology 2004;113(3):470-4.
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2004: Vrtala Susanne; Focke-Tejkl Margarete; Swoboda Ines; Kraft Dietrich; Valenta Rudolf
Strategies for converting allergens into hypoallergenic vaccine candidates.
Methods (San Diego, Calif.) 2004;32(3):313-20.
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2004: Valent Peter; Hauswirth Alexander W; Natter Susanne; Sperr Wolfgang R; Bühring Hans-Jörg; Valenta Rudolf
Assays for measuring in vitro basophil activation induced by recombinant allergens.
Methods (San Diego, Calif.) 2004;32(3):265-70.
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2004: Mothes Nadine; Westritschnig Kerstin; Valenta Rudolf
Tree pollen allergens.
Clinical allergy and immunology 2004;18():165-84.
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2004: Valenta R; Ball T; Focke M; Linhart B; Mothes N; Niederberger V; Spitzauer S; Swoboda I; Vrtala S; Westritschnig K; Kraft D
Immunotherapy of allergic disease.
Advances in immunology 2004;82():105-53.
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2003: Reininger R; Swoboda I; Bohle B; Hauswirth A W; Valent P; Rumpold H; Valenta R; Spitzauer S
Characterization of recombinant cat albumin.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(12):1695-702.
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2003: Westritschnig Kerstin; Valenta Rudolf
Can we genetically engineer safer and more effective immunotherapy reagents?
Current opinion in allergy and clinical immunology 2003;3(6):495-500.
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2003: Focke Margarete; Hemmer W; Valenta R; Götz M; Jarisch R
Identification of oilseed rape (Brassica napus) pollen profilin as a cross-reactive allergen.
International archives of allergy and immunology 2003;132(2):116-23.
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2003: Grönlund Hans; Bergman Tomas; Sandström Kristofer; Alvelius Gunvor; Reininger Renate; Verdino Petra; Hauswirth Alexander; Liderot Karin; Valent Peter; Spitzauer Susanne; Keller Walter; Valenta Rudolf; van Hage-Hamsten Marianne
Formation of disulfide bonds and homodimers of the major cat allergen Fel d 1 equivalent to the natural allergen by expression in Escherichia coli.
The Journal of biological chemistry 2003;278(41):40144-51.
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2003: Flicker Sabine; Valenta Rudolf
Renaissance of the blocking antibody concept in type I allergy.
International archives of allergy and immunology 2003;132(1):13-24.
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2003: Mothes N; Heinzkill M; Drachenberg K J; Sperr W R; Krauth M T; Majlesi Y; Semper H; Valent P; Niederberger V; Kraft D; Valenta R
Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(9):1198-208.
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2003: Laffer Sylvia; Hamdi Said; Lupinek Christian; Sperr Wolfgang R; Valent Peter; Verdino Petra; Keller Walter; Grote Monika; Hoffmann-Sommergruber Karin; Scheiner Otto; Kraft Dietrich; Rideau Marc; Valenta Rudolf
Molecular characterization of recombinant T1, a non-allergenic periwinkle (Catharanthus roseus) protein, with sequence similarity to the Bet v 1 plant allergen family.
The Biochemical journal 2003;373(Pt 1):261-9.
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2003: Grote Monika; Valenta Rudolf; Reichelt Rudolf
Abortive pollen germination: a mechanism of allergen release in birch, alder, and hazel revealed by immunogold electron microscopy.
The Journal of allergy and clinical immunology 2003;111(5):1017-23.
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2003: Stumvoll Sabine; Westritschnig Kerstin; Lidholm Jonas; Spitzauer Susanne; Colombo Paolo; Duro Giovanni; Kraft Dietrich; Geraci Domenico; Valenta Rudolf
Identification of cross-reactive and genuine Parietaria judaica pollen allergens.
The Journal of allergy and clinical immunology 2003;111(5):974-9.
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2003: Reininger R; Exner H; Kuderna C; Rumpold H; Balic N; Valenta R; Spitzauer S
Possible modes of allergen-specific sensitization and boosting in an atopic child.
International archives of allergy and immunology 2003;130(4):275-9.
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2003: Verdino Petra; Westritschnig Kerstin; Valenta Rudolf; Keller Walter
Three-dimensional structure of the panallergen Phl p 7.
International archives of allergy and immunology 2003;130(1):10-1.
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2003: Westritschnig K; Sibanda E; Thomas W; Auer H; Aspöck H; Pittner G; Vrtala S; Spitzauer S; Kraft D; Valenta R
Analysis of the sensitization profile towards allergens in central Africa.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(1):22-7.
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2003: Harwanegg C; Laffer S; Hiller R; Mueller M W; Kraft D; Spitzauer S; Valenta R
Microarrayed recombinant allergens for diagnosis of allergy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(1):7-13.
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2003: Majlesi Yasamin; Samorapoompichit Puchit; Hauswirth Alexander W; Schernthaner Gerit-Holger; Ghannadan Minoo; Baghestanian Mehrdad; Rezaie-Majd Abdolreza; Valenta Rudolf; Sperr Wolfgang R; Bühring Hans-Jörg; Valent Peter
Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3.
Journal of leukocyte biology 2003;73(1):107-17.
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2002: Grönlund Hans; Vrtala Susanne; Wiedermann Ursula; Dekan Gerhard; Kraft Dietrich; Valenta Rudolf; Van Hage-Hamsten Marianne
Carbohydrate-based particles: a new adjuvant for allergen-specific immunotherapy.
Immunology 2002;107(4):523-9.
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2002: Valenta Rudolf; Kraft Dietrich
From allergen structure to new forms of allergen-specific immunotherapy.
Current opinion in immunology 2002;14(6):718-27.
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2002: Mossabeb Roschanak; Seiberler Susanne; Mittermann Irene; Reininger Renate; Spitzauer Susanne; Natter Susanne; Verdino Petra; Keller Walter; Kraft Dietrich; Valenta Rudolf
Characterization of a novel isoform of alpha-nascent polypeptide-associated complex as IgE-defined autoantigen.
The Journal of investigative dermatology 2002;119(4):820-9.
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2002: Budde Ilona Kleine; de Heer Pleuni G; Natter Susanne; Mahler Vera; van der Zee Jaring S; Valenta Rudolf; Aalberse Rob C
Studies on the association between immunoglobulin E autoreactivity and immunoglobulin E-dependent histamine-releasing factors.
Immunology 2002;107(2):243-51.
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2002: van Hage-Hamsten M; Johansson E; Roquet A; Peterson C; Andersson M; Greiff L; Vrtala S; Valenta R; Grönneberg R
Nasal challenges with recombinant derivatives of the major birch pollen allergen Bet v 1 induce fewer symptoms and lower mediator release than rBet v 1 wild-type in patients with allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(10):1448-53.
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2002: Verdino Petra; Westritschnig Kerstin; Valenta Rudolf; Keller Walter
The cross-reactive calcium-binding pollen allergen, Phl p 7, reveals a novel dimer assembly.
The EMBO journal 2002;21(19):5007-16.
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2002: Stumvoll Sabine; Lidholm Jonas; Thunberg Roland; DeWitt Asa Marknell; Eibensteiner Petra; Swoboda Ines; Bugajska-Schretter Agnes; Spitzauer Susanne; Vangelista Luca; Kazemi-Shirazi Lili; Sperr Wolfgang R; Valent Peter; Kraft Dietrich; Valenta Rudolf
Purification, structural and immunological characterization of a timothy grass (Phleum pratense) pollen allergen, Phl p 4, with cross-reactive potential.
Biological chemistry 2002;383(9):1383-96.
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2002: Marknell DeWitt A; Niederberger V; Lehtonen P; Spitzauer S; Sperr W R; Valent P; Valenta R; Lidholm J
Molecular and immunological characterization of a novel timothy grass (Phleum pratense) pollen allergen, Phl p 11.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(9):1329-40.
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2002: Movérare Robert; Westritschnig Kerstin; Svensson Margareta; Hayek Brigitte; Bende Mats; Pauli Gabrielle; Sorva Ritva; Haahtela Tari; Valenta Rudolf; Elfman Lena
Different IgE reactivity profiles in birch pollen-sensitive patients from six European populations revealed by recombinant allergens: an imprint of local sensitization.
International archives of allergy and immunology 2002;128(4):325-35.
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2002: Flicker Sabine; Steinberger Peter; Norderhaug Lars; Sperr Wolfgang R; Majlesi Yasamin; Valent Peter; Kraft Dietrich; Valenta Rudolf
Conversion of grass pollen allergen-specific human IgE into a protective IgG(1) antibody.
European journal of immunology 2002;32(8):2156-62.
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2002: Linhart Birgit; Jahn-Schmid Beatrice; Verdino Petra; Keller Walter; Ebner Christof; Kraft Dietrich; Valenta Rudolf
Combination vaccines for the treatment of grass pollen allergy consisting of genetically engineered hybrid molecules with increased immunogenicity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1301-3.
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2002: Hauswirth Alexander W; Natter Susanne; Ghannadan Minoo; Majlesi Yasamin; Schernthaner Gerit-Holger; Sperr Wolfgang R; Bühring Hans-Jörg; Valenta Rudolf; Valent Peter
Recombinant allergens promote expression of CD203c on basophils in sensitized individuals.
The Journal of allergy and clinical immunology 2002;110(1):102-9.
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2002: Valenta Rudolf
The future of antigen-specific immunotherapy of allergy.
Nature reviews. Immunology 2002;2(6):446-53.
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2002: Niederberger V; Purohit A; Oster J P; Spitzauer S; Valenta R; Pauli G
The allergen profile of ash (Fraxinus excelsior) pollen: cross-reactivity with allergens from various plant species.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(6):933-41.
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2002: Swoboda Ines; Bugajska-Schretter Agnes; Verdino Petra; Keller Walter; Sperr Wolfgang R; Valent Peter; Valenta Rudolf; Spitzauer Susanne
Recombinant carp parvalbumin, the major cross-reactive fish allergen: a tool for diagnosis and therapy of fish allergy.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4576-84.
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2002: Kazemi-Shirazi Lili; Niederberger Verena; Linhart Birgit; Lidholm Jonas; Kraft Dietrich; Valenta Rudolf
Recombinant marker allergens: diagnostic gatekeepers for the treatment of allergy.
International archives of allergy and immunology 2002;127(4):259-68.
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2002: Kazemi-Shirazi L; Gasche C H; Natter S; Gangl A; Smolen J; Spitzauer S; Valent P; Kraft D; Valenta R
IgA autoreactivity: a feature common to inflammatory bowel and connective tissue diseases.
Clinical and experimental immunology 2002;128(1):102-9.
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2002: Kinaciyan Tamar; Natter Susanne; Kraft Dietrich; Stingl Georg; Valenta Rudolf
IgE autoantibodies monitored in a patient with atopic dermatitis under cyclosporin A treatment reflect tissue damage.
The Journal of allergy and clinical immunology 2002;109(4):717-9.
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2002: Tinghino Raffaella; Twardosz Anna; Barletta Bianca; Puggioni Eleonora M r; Iacovacci Patrizia; Butteroni Cinzia; Afferni Claudia; Mari Adriano; Hayek Brigitte; Di Felice Gabriella; Focke Margarete; Westritschnig Kerstin; Valenta Rudolf; Pini Carlo
Molecular, structural, and immunologic relationships between different families of recombinant calcium-binding pollen allergens.
The Journal of allergy and clinical immunology 2002;109(2):314-20.
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2002: Niederberger Verena; Niggemann Bodo; Kraft Dietrich; Spitzauer Susanne; Valenta Rudolf
Evolution of IgM, IgE and IgG(1-4 )antibody responses in early childhood monitored with recombinant allergen components: implications for class switch mechanisms.
European journal of immunology 2002;32(2):576-84.
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2002: Swoboda Ines; De Weerd Nicole; Bhalla Prem L; Niederberger Verena; Sperr W R; Valent Peter; Kahlert Helga; Fiebig Helmut; Verdino Petra; Keller Walter; Ebner Christof; Spitzauer Susanne; Valenta Rudolf; Singh Mohan B
Mutants of the major ryegrass pollen allergen, Lol p 5, with reduced IgE-binding capacity: candidates for grass pollen-specific immunotherapy.
European journal of immunology 2002;32(1):270-80.
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2002: Valenta R
Recombinant allergen-based concepts for diagnosis and therapy of type I allergy.
Allergy 2002;57 Suppl 71():66-7.
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2002: Swoboda Ines; Bugajska-Schretter A; Valenta R; Spitzauer S
Recombinant fish parvalbumins: Candidates for diagnosis and treatment of fish allergy.
Allergy 2002;57 Suppl 72():94-6.
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2002: Valenta Rudolf; Vrtala Susanne; Focke-Tejkl Margit; Twardosz Anna; Swoboda Ines; Bugajska-Schretter Agnes; Spitzauer Susanne; Kraft Dietrich
Synthetic and genetically engineered allergen derivatives for specific immunotherapy of type I allergy.
Clinical allergy and immunology 2002;16():495-517.
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2001: Binder M; Mahler V; Hayek B; Sperr W R; Schöller M; Prozell S; Wiedermann G; Valent P; Valenta R; Duchêne M
Molecular and immunological characterization of arginine kinase from the Indianmeal moth, Plodia interpunctella, a novel cross-reactive invertebrate pan-allergen.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5470-7.
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2001: Niederberger V; Stübner P; Spitzauer S; Kraft D; Valenta R; Ehrenberger K; Horak F
Skin test results but not serology reflect immediate type respiratory sensitivity: a study performed with recombinant allergen molecules.
The Journal of investigative dermatology 2001;117(4):848-51.
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2001: Sperr W R; Jordan J H; Baghestanian M; Kiener H P; Samorapoompichit P; Semper H; Hauswirth A; Schernthaner G H; Chott A; Natter S; Kraft D; Valenta R; Schwartz L B; Geissler K; Lechner K; Valent P
Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia.
Blood 2001;98(7):2200-9.
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2001: Wiedermann U; Herz U; Baier K; Vrtala S; Neuhaus-Steinmetz U; Bohle B; Dekan G; Renz H; Ebner C; Valenta R; Kraft D
Intranasal treatment with a recombinant hypoallergenic derivative of the major birch pollen allergen Bet v 1 prevents allergic sensitization and airway inflammation in mice.
International archives of allergy and immunology 2001;126(1):68-77.
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2001: Laffer S; Hogbom E; Roux K H; Sperr W R; Valent P; Bankl H C; Vangelista L; Kricek F; Kraft D; Grönlund H; Valenta R
A molecular model of type I allergy: identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcepsilonRI interaction and reacts with receptor-bound IgE.
The Journal of allergy and clinical immunology 2001;108(3):409-16.
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2001: Focke M; Mahler V; Ball T; Sperr W R; Majlesi Y; Valent P; Kraft D; Valenta R
Nonanaphylactic synthetic peptides derived from B cell epitopes of the major grass pollen allergen, Phl p 1, for allergy vaccination.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):2042-4.
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2001: Vrtala S; Hirtenlehner K; Susani M; Akdis M; Kussebi F; Akdis C A; Blaser K; Hufnagl P; Binder B R; Politou A; Pastore A; Vangelista L; Sperr W R; Semper H; Valent P; Ebner C; Kraft D; Valenta R
Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):2045-7.
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2001: Mossabeb R; Kraft D; Valenta R
Evaluation of the allergenic potential of Ginkgo biloba extracts.
Wiener klinische Wochenschrift 2001;113(15-16):580-7.
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2001: Swoboda I; Bhalla P L; Xu H; Zhang Y; Mittermann I; Valenta R; Singh M B
Identification of pronp1, a tobacco profilin gene activated in tip-growing cells.
Plant molecular biology 2001;46(5):531-8.
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2001: Grote M; Vrtala S; Niederberger V; Wiermann R; Valenta R; Reichelt R
Release of allergen-bearing cytoplasm from hydrated pollen: a mechanism common to a variety of grass (Poaceae) species revealed by electron microscopy.
The Journal of allergy and clinical immunology 2001;108(1):109-15.
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2001: Natter S; Granditsch G; Reichel G L; Baghestanian M; Valent P; Elfman L; Grönlund H; Kraft D; Valenta R
IgA cross-reactivity between a nuclear autoantigen and wheat proteins suggests molecular mimicry as a possible pathomechanism in celiac disease.
European journal of immunology 2001;31(3):918-28.
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2001: Valenta R; Kraft D
Recombinant allergen molecules: tools to study effector cell activation.
Immunological reviews 2001;179():119-27.
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2001: Focke M; Mahler V; Ball T; Kraft D; Valenta R
Nonallergenic peptides from surface-exposed areas or B-cell epitopes of allergens for specific immunotherapy.
International archives of allergy and immunology 2001;124(1-3):398-9.
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2001: Wiedermann U; Herz U; Vrtala S; Neuhaus-Steinmetz U; Renz H; Ebner C; Valenta R; Kraft D
Mucosal tolerance induction with hypoallergenic molecules in a murine model of allergic asthma.
International archives of allergy and immunology 2001;124(1-3):391-4.
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2001: Mahler V; Fischer S; Heiss S; Duchêne M; Kraft D; Valenta R
cDna cloning and characterization of a cross-reactive birch pollen allergen: identification as a pectin esterase.
International archives of allergy and immunology 2001;124(1-3):64-6.
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2001: Laffer S; Steinberger P; Kraft D; Valenta R
Promiscuous use of light chains by human IgE antibodies specific for three major grass pollen allergens.
International archives of allergy and immunology 2001;124(1-3):29-30.
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2000: Vrtala S; Akdis C A; Budak F; Akdis M; Blaser K; Kraft D; Valenta R
T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6653-9.
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2000: Flicker S; Vrtala S; Steinberger P; Vangelista L; Bufe A; Petersen A; Ghannadan M; Sperr W R; Valent P; Norderhaug L; Bohle B; Stockinger H; Suphioglu C; Ong E K; Kraft D; Valenta R
A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural characterization of the epitope-containing domain.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):3849-59.
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2000: Eibensteiner P; Spitzauer S; Steinberger P; Kraft D; Valenta R
Immunoglobulin E antibodies of atopic individuals exhibit a broad usage of VH-gene families.
Immunology 2000;101(1):112-9.
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2000: Sperr W R; Natter S; Baghestanian M; Smolen J; Wolff K; Binder B R; Müller M R; Lechner K; Valenta R; Valent P
Autoantibody reactivity in a case of Schnitzler's syndrome: evidence for a Th1-like response and detection of IgG2 anti-FcepsilonRIalpha antibodies.
International archives of allergy and immunology 2000;122(4):279-86.
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2000: Pauli G; Purohit A; Oster J P; De Blay F; Vrtala S; Niederberger V; Kraft D; Valenta R
Comparison of genetically engineered hypoallergenic rBet v 1 derivatives with rBet v 1 wild-type by skin prick and intradermal testing: results obtained in a French population.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(8):1076-84.
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2000: Nopp A; Halldén G; Lundahl J; Johansson E; Vrtala S; Valenta R; Grönneberg R; Van Hage-Hamsten M
Comparison of inflammatory responses to genetically engineered hypoallergenic derivatives of the major birch pollen allergen bet v 1 and to recombinant bet v 1 wild type in skin chamber fluids collected from birch pollen-allergic patients.
The Journal of allergy and clinical immunology 2000;106(1 Pt 1):101-9.
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2000: Grote M; Vrtala S; Niederberger V; Valenta R; Reichelt R
Expulsion of allergen-containing materials from hydrated rye grass (Lolium perenne) pollen revealed by using immunogold field emission scanning and transmission electron microscopy.
The Journal of allergy and clinical immunology 2000;105(6 Pt 1):1140-5.
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2000: Mahler V; Diepgen T L; Kubeta O; Leakakos T; Truscott W; Schuler G; Kraft D; Valenta R
Mutual boosting effects of sensitization with timothy grass pollen and latex glove extract on IgE antibody responses in a mouse model.
The Journal of investigative dermatology 2000;114(5):1039-43.
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2000: Bugajska-Schretter A; Grote M; Vangelista L; Valent P; Sperr W R; Rumpold H; Pastore A; Reichelt R; Valenta R; Spitzauer S
Purification, biochemical, and immunological characterisation of a major food allergen: different immunoglobulin E recognition of the apo- and calcium-bound forms of carp parvalbumin.
Gut 2000;46(5):661-9.
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2000: Aghayan-Ugurluoglu R; Ball T; Vrtala S; Schweiger C; Kraft D; Valenta R
Dissociation of allergen-specific IgE and IgA responses in sera and tears of pollen-allergic patients: a study performed with purified recombinant pollen allergens.
The Journal of allergy and clinical immunology 2000;105(4):803-13.
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2000: Mahler V; Fischer S; Fuchs T; Ghannadan M; Valent P; Fartasch M; Kraft D; Schuler G; Valenta R
Prevention of latex allergy by selection of low-allergen gloves.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(4):509-20.
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2000: Grote M; Mahler V; Spitzauer S; Fuchs T; Valenta R; Reichelt R
In situ localization of latex allergens in 3 different brands of latex gloves by means of immunogold field emission scanning and transmission electron microscopy.
The Journal of allergy and clinical immunology 2000;105(3):561-9.
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2000: Valenta R; Seiberler S; Natter S; Mahler V; Mossabeb R; Ring J; Stingl G
Autoallergy: a pathogenetic factor in atopic dermatitis?
The Journal of allergy and clinical immunology 2000;105(3):432-7.
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2000: Pandjaitan B; Swoboda I; Brandejsky-Pichler F; Rumpold H; Valenta R; Spitzauer S
Escherichia coli expression and purification of recombinant dog albumin, a cross-reactive animal allergen.
The Journal of allergy and clinical immunology 2000;105(2 Pt 1):279-85.
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2000: Flicker S; Laffer S; Steinberger P; Alhani B; Zhu Y; Laukkanen M L; Keinänen K; Kraft D; Valenta R
Engineering, purification and applications of His-tagged recombinant antibody fragments with specificity for the major birch pollen allergen, bet v1.
Biological chemistry 2000;381(1):39-47.
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2000: Kazemi-Shirazi L; Pauli G; Purohit A; Spitzauer S; Fröschl R; Hoffmann-Sommergruber K; Breiteneder H; Scheiner O; Kraft D; Valenta R
Quantitative IgE inhibition experiments with purified recombinant allergens indicate pollen-derived allergens as the sensitizing agents responsible for many forms of plant food allergy.
The Journal of allergy and clinical immunology 2000;105(1 Pt 1):116-25.
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2000: Denépoux S; Eibensteiner P B; Steinberger P; Vrtala S; Visco V; Weyer A; Kraft D; Banchereau J; Valenta R; Lebecque S
Molecular characterization of human IgG monoclonal antibodies specific for the major birch pollen allergen Bet v 1. Anti-allergen IgG can enhance the anaphylactic reaction.
FEBS letters 2000;465(1):39-46.
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1999: Grote M; Hayek B; Reichelt R; Kraft D; Valenta R
Immunogold electron microscopic localization of the cross-reactive two-EF-hand calcium-binding birch pollen allergen Bet v 4 in dry and rehydrated birch pollen.
International archives of allergy and immunology 1999;120(4):287-94.
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1999: Heiss S; Mahler V; Steiner R; Spitzauer S; Schweiger C; Kraft D; Valenta R
Component-resolved diagnosis (CRD) of type I allergy with recombinant grass and tree pollen allergens by skin testing.
The Journal of investigative dermatology 1999;113(5):830-7.
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1999: Vrtala S; Fischer S; Grote M; Vangelista L; Pastore A; Sperr W R; Valent P; Reichelt R; Kraft D; Valenta R
Molecular, immunological, and structural characterization of Phl p 6, a major allergen and P-particle-associated protein from Timothy grass (Phleum pratense) pollen.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5489-96.
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1999: van Hage-Hamsten M; Kronqvist M; Zetterström O; Johansson E; Niederberger V; Vrtala S; Grönlund H; Grönneberg R; Valenta R
Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: results obtained with a mix of two recombinant Bet v 1 fragments and recombinant Bet v 1 trimer in a Swedish population before the birch pollen season.
The Journal of allergy and clinical immunology 1999;104(5):969-77.
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1999: Seiberler S; Natter S; Hufnagl P; Binder B R; Valenta R
Characterization of IgE-reactive autoantigens in atopic dermatitis. 2. A pilot study on IgE versus IgG subclass response and seasonal variation of IgE autoreactivity.
International archives of allergy and immunology 1999;120(2):117-25.
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1999: Seiberler S; Bugajska-Schretter A; Hufnagl P; Binder B R; Stöckl J; Spitzauer S; Valent P; Valenta R
Characterization of IgE-reactive autoantigens in atopic dermatitis. 1. Subcellular distribution and tissue-specific expression.
International archives of allergy and immunology 1999;120(2):108-16.
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1999: Pandjaitan B; Eibensteiner P B; Vrtala S; Hayek B; Grote M; Reichelt R; Rumpold H; Valenta R; Spitzauer S
pET-prof, a plasmid for high-level expression of recombinant peptides fused to a birch profilin-derived hexadecapeptide tag: a system for the detection and presentation of recombinant antigens.
Gene 1999;237(2):333-42.
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1999: De Marino S; Morelli M A; Fraternali F; Tamborini E; Musco G; Vrtala S; Dolecek C; Arosio P; Valenta R; Pastore A
An immunoglobulin-like fold in a major plant allergen: the solution structure of Phl p 2 from timothy grass pollen.
Structure (London, England : 1993) 1999;7(8):943-52.
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1999: Ball T; Fuchs T; Sperr W R; Valent P; Vangelista L; Kraft D; Valenta R
B cell epitopes of the major timothy grass pollen allergen, phl p 1, revealed by gene fragmentation as candidates for immunotherapy.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(11):1277-90.
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1999: Valenta R; Vrtala S; Focke-Tejkl M; Bugajska-Schretter; Ball T; Twardosz A; Spitzauer S; Grönlund H; Kraft D
Genetically engineered and synthetic allergen derivatives: candidates for vaccination against type I allergy.
Biological chemistry 1999;380(7-8):815-24.
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1999: Valenta R; Lidholm J; Niederberger V; Hayek B; Kraft D; Grönlund H
The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT).
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(7):896-904.
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1999: Ball T; Sperr W R; Valent P; Lidholm J; Spitzauer S; Ebner C; Kraft D; Valenta R
Induction of antibody responses to new B cell epitopes indicates vaccination character of allergen immunotherapy.
European journal of immunology 1999;29(6):2026-36.
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1999: Vangelista L; Laffer S; Turek R; Grönlund H; Sperr W R; Valent P; Pastore A; Valenta R
The immunoglobulin-like modules Cepsilon3 and alpha2 are the minimal units necessary for human IgE-FcepsilonRI interaction.
The Journal of clinical investigation 1999;103(11):1571-8.
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1999: Niederberger V; Hayek B; Vrtala S; Laffer S; Twardosz A; Vangelista L; Sperr W R; Valent P; Rumpold H; Kraft D; Ehrenberger K; Valenta R; Spitzauer S
Calcium-dependent immunoglobulin E recognition of the apo- and calcium-bound form of a cross-reactive two EF-hand timothy grass pollen allergen, Phl p 7.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):843-56.
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1999: Bugajska-Schretter A; Pastore A; Vangelista L; Rumpold H; Valenta R; Spitzauer S
Molecular and immunological characterization of carp parvalbumin, a major fish allergen.
International archives of allergy and immunology 1999;118(2-4):306-8.
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1999: Vrtala S; Hirtenlehner K; Susani M; Hufnagl P; Binder B R; Vangelista L; Pastore A; Sperr W R; Valent P; Ebner C; Kraft D; Valenta R
Genetic engineering of recombinant hypoallergenic oligomers of the major birch pollen allergen, Bet v 1: candidates for specific immunotherapy.
International archives of allergy and immunology 1999;118(2-4):218-9.
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1999: Pauli G; Purohit A; Oster J P; de Blay F; Vrtala S; Niederberger V; Kraft D; Valenta R
Clinical evaluation of genetically engineered hypoallergenic rBet v 1 derivatives.
International archives of allergy and immunology 1999;118(2-4):216-7.
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1999: Ball T; Fuchs T; Kraft D; Valenta R
Lessons from the antibody recognition of the major Timothy grass pollen allergen Phl p 1.
International archives of allergy and immunology 1999;118(2-4):208-9.
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1999: Eibensteiner P; Denépoux S; Steinberger P; Kraft D; Visco V; Banchereau J; Lebecque S; Valenta R
Expression of a human IgG4 antibody, BAB2, with specificity for the major Birch pollen allergen, Bet v 1 in Escherichia coli: recombinant BAB2 Fabs enhance the allergic reaction.
International archives of allergy and immunology 1999;118(2-4):190-2.
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1999: Kraft D; Ferreira F; Vrtala S; Breiteneder H; Ebner C; Valenta R; Susani M; Breitenbach M; Scheiner O
The importance of recombinant allergens for diagnosis and therapy of IgE-mediated allergies.
International archives of allergy and immunology 1999;118(2-4):171-6.
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1999: Laffer S; Hogbom E; Adrianson J; Grönlund H; Sillaber C; Valent P; Vangelista L; Kricek F; Kraft D; Valenta R
An in vitro model for the allergen-IgE-FcARI interaction.
International archives of allergy and immunology 1999;118(2-4):116-8.
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1999: Skyllouriotis P; Skyllouriotis-Lazarou M; Natter S; Steiner R; Spitzauer S; Kapiotis S; Valent P; Hirschl A M; Guber S E; Laufer G; Wollenek G; Wolner E; Wimmer M; Valenta R
IgG subclass reactivity to human cardiac myosin in cardiomyopathy patients is indicative of a Th1-like autoimmune disease.
Clinical and experimental immunology 1999;115(2):236-47.
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1999: Valenta R; Twardosz A; Vrtala S; Kraft D
Large scale production and quality criteria of recombinant allergens.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 1999;(93):211-24; discussion 224-5.
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1999: Pauli G; Purohit A; Oster J P; de Blay F; Vrtala S; Niederberger V; Kraft D; Valenta R
Skin testing with wild-type recombinant birch pollen allergens and hypoallergenic modified molecules.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 1999;(93):203-10.
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1999: Valenta R; Natter S; Seiberler S; Roschanak M; Mothes N; Mahler V; Eibensteiner P
Autoallergy: a pathogenetic factor in atopic dermatitis?
Current problems in dermatology 1999;28():45-50.
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1998: Hayek B; Vangelista L; Pastore A; Sperr W R; Valent P; Vrtala S; Niederberger V; Twardosz A; Kraft D; Valenta R
Molecular and immunologic characterization of a highly cross-reactive two EF-hand calcium-binding alder pollen allergen, Aln g 4: structural basis for calcium-modulated IgE recognition.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):7031-9.
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1998: Valenta R; Natter S; Seiberler S; Wichlas S; Maurer D; Hess M; Pavelka M; Grote M; Ferreira F; Szepfalusi Z; Valent P; Stingl G
Molecular characterization of an autoallergen, Hom s 1, identified by serum IgE from atopic dermatitis patients.
The Journal of investigative dermatology 1998;111(6):1178-83.
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1998: Valenta R; Hayek B; Seiberler S; Bugajska-Schretter A; Niederberger V; Twardosz A; Natter S; Vangelista L; Pastore A; Spitzauer S; Kraft D
Calcium-binding allergens: from plants to man.
International archives of allergy and immunology 1998;117(3):160-6.
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1998: Natter S; Seiberler S; Hufnagl P; Binder B R; Hirschl A M; Ring J; Abeck D; Schmidt T; Valent P; Valenta R
Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(14):1559-69.
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1998: Niederberger V; Pauli G; Grönlund H; Fröschl R; Rumpold H; Kraft D; Valenta R; Spitzauer S
Recombinant birch pollen allergens (rBet v 1 and rBet v 2) contain most of the IgE epitopes present in birch, alder, hornbeam, hazel, and oak pollen: a quantitative IgE inhibition study with sera from different populations.
The Journal of allergy and clinical immunology 1998;102(4 Pt 1):579-91.
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1998: Valenta R; Almo S; Ball T; Dolecek C; Steinberger P; Laffer S; Eibensteiner P; Flicker S; Vrtala S; Spitzauer S; Valent P; Denepoux S; Kraft D; Banchereau J; Lebecque S
The immunoglobulin E-allergen interaction: a target for therapy of type I allergic diseases.
International archives of allergy and immunology 1998;116(3):167-76.
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1998: Valenta R; Vrtala S; Laffer S; Spitzauer S; Kraft D
Recombinant allergens.
Allergy 1998;53(6):552-61.
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1998: Vrtala S; Ball T; Spitzauer S; Pandjaitan B; Suphioglu C; Knox B; Sperr W R; Valent P; Kraft D; Valenta R
Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):6137-44.
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1998: Carpin S; Laffer S; Schoentgen F; Valenta R; Chénieux J C; Rideau M; Hamdi S
Molecular characterization of a cytokinin-inducible periwinkle protein showing sequence homology with pathogenesis-related proteins and the Bet v 1 allergen family.
Plant molecular biology 1998;36(5):791-8.
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1998: Niederberger V; Laffer S; Fröschl R; Kraft D; Rumpold H; Kapiotis S; Valenta R; Spitzauer S
IgE antibodies to recombinant pollen allergens (Phl p 1, Phl p 2, Phl p 5, and Bet v 2) account for a high percentage of grass pollen-specific IgE.
The Journal of allergy and clinical immunology 1998;101(2 Pt 1):258-64.
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1998: Grote M; Fischer S; Müller W D; Valenta R
In situ localization of a high molecular weight cross-reactive allergen in pollen and plant-derived food by immunogold electron microscopy.
The Journal of allergy and clinical immunology 1998;101(2 Pt 1):250-7.
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1998: Hirschwehr R; Heppner C; Spitzauer S; Sperr W R; Valent P; Berger U; Horak F; Jäger S; Kraft D; Valenta R
Identification of common allergenic structures in mugwort and ragweed pollen.
The Journal of allergy and clinical immunology 1998;101(2 Pt 1):196-206.
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1998: Bugajska-Schretter A; Elfman L; Fuchs T; Kapiotis S; Rumpold H; Valenta R; Spitzauer S
Parvalbumin, a cross-reactive fish allergen, contains IgE-binding epitopes sensitive to periodate treatment and Ca2+ depletion.
The Journal of allergy and clinical immunology 1998;101(1 Pt 1):67-74.
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1998: Grote M; Wiedemann P; Lebecque S; Valenta R
Human monoclonal IgG antibodies derived from a patient allergic to birch pollen as tools to study the in situ localization of the major birch pollen allergen, Bet v 1, by immunogold electron microscopy.
The Journal of allergy and clinical immunology 1998;101(1 Pt 1):60-6.
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1998: Kraft D; Ferreira F; Ebner C; Valenta R; Breiteneder H; Susani M; Breitenbach M; Scheiner O
Recombinant allergens: the future of the diagnosis and treatment of atopic allergy.
Allergy 1998;53(45 Suppl):62-6.
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1997: Twardosz A; Hayek B; Seiberler S; Vangelista L; Elfman L; Grönlund H; Kraft D; Valenta R
Molecular characterization, expression in Escherichia coli, and epitope analysis of a two EF-hand calcium-binding birch pollen allergen, Bet v 4.
Biochemical and biophysical research communications 1997;239(1):197-204.
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1997: Sperr W R; Agis H; Semper H; Valenta R; Susani M; Sperr M; Willheim M; Scheiner O; Liehl E; Lechner K; Valent P
Inhibition of allergen-induced histamine release from human basophils by cyclosporine A and FK-506.
International archives of allergy and immunology 1997;114(1):68-73.
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1997: Valenta R; Flicker S; Eibensteiner P B; Steinberger P; Laffer S; Dolecek C; Kraft D
Recombinant allergen-specific antibody fragments: tools for diagnosis, prevention and therapy of type I allergy.
Biological chemistry 1997;378(8):745-9.
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1997: Laffer S; Vangelista L; Steinberger P; Kraft D; Pastore A; Valenta R
Bip 1, a monoclonal antibody with specificity for the major birch pollen allergen Bet v 1, modulates IgE binding to the allergen.
International archives of allergy and immunology 1997;113(1-3):260-1.
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1997: Steinberger P; Kraft D; Valenta R
Expression in Escherichia coli of human IgE antibody fragments with specificity for major timothy grass pollen allergens using the combinatorial library approach.
International archives of allergy and immunology 1997;113(1-3):258-9.
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1997: Vrtala S; Hirtenlehner K; Vangelista L; Pastore A; Eichler H G; Sperr W R; Valent P; Ebner C; Kraft D; Valenta R
Division of the major birch pollen allergen, Bet v 1, into two non-anaphylactic fragments.
International archives of allergy and immunology 1997;113(1-3):246-8.
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1997: Valenta R; Natter S; Seiberler S; Grote M
Isolation of cDNAs coding for IgE autoantigens: a link between atopy and autoimmunity.
International archives of allergy and immunology 1997;113(1-3):209-12.
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1997: Fedorov A A; Ball T; Valenta R; Almo S C
X-ray crystal structures of birch pollen profilin and Phl p 2.
International archives of allergy and immunology 1997;113(1-3):109-13.
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1997: Flicker S H; Schneider S M; Offterdinger M; Dittrich E; Fazeny B; Valenta R; Huber H; Dittrich C; Grunt T W
Tyrosine kinase signaling pathways control the expression of retinoic acid receptor-alpha in SK-BR-3 breast cancer cells.
Cancer letters 1997;115(1):63-72.
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1997: Vrtala S; Hirtenlehner K; Vangelista L; Pastore A; Eichler H G; Sperr W R; Valent P; Ebner C; Kraft D; Valenta R
Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapy.
The Journal of clinical investigation 1997;99(7):1673-81.
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1997: Lebecque S; Dolecek C; Laffer S; Visco V; Denépoux S; Pin J J; Guret C; Boltz-Nitulescu G; Weyer A; Valenta R
Immunologic characterization of monoclonal antibodies that modulate human IgE binding to the major birch pollen allergen Bet v 1.
The Journal of allergy and clinical immunology 1997;99(3):374-84.
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1997: Spitzauer S; Valenta R; Mühl S; Rumpold H; Ebner H; Ebner C
Characterization of allergens from deer: cross-reactivity with allergens from cow dander.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1997;27(2):196-200.
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1997: Fedorov A A; Ball T; Mahoney N M; Valenta R; Almo S C
The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin.
Structure (London, England : 1993) 1997;5(1):33-45.
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1997: Spitzauer S; Pandjaitan B; Mühl S; Ebner C; Kraft D; Valenta R; Rumpold H
Major cat and dog allergens share IgE epitopes.
The Journal of allergy and clinical immunology 1997;99(1 Pt 1):100-6.
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1997: Valenta R; Steinberger P; Laffer S; Dolecek C; Wiedemann P; Flicker S; Kraft D
Cloning allergen-specific antibody fragments (Fabs); tools for allergen standardization and therapy of type I allergy.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 1997;(91):222-9.
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1996: Laffer S; Vangelista L; Steinberger P; Kraft D; Pastore A; Valenta R
Molecular characterization of Bip 1, a monoclonal antibody that modulates IgE binding to birch pollen allergen, Bet v 1.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):4953-62.
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1996: Wiedemann P; Giehl K; Almo S C; Fedorov A A; Girvin M; Steinberger P; Rüdiger M; Ortner M; Sippl M; Dolecek C; Kraft D; Jockusch B; Valenta R
Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody.
The Journal of biological chemistry 1996;271(47):29915-21.
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1996: Heiss S; Fischer S; Müller W D; Weber B; Hirschwehr R; Spitzauer S; Kraft D; Valenta R
Identification of a 60 kd cross-reactive allergen in pollen and plant-derived food.
The Journal of allergy and clinical immunology 1996;98(5 Pt 1):938-47.
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1996: Vrtala S; Mayer P; Ferreira F; Susani M; Sehon A H; Kraft D; Valenta R
Induction of IgE antibodies in mice and rhesus monkeys with recombinant birch pollen allergens: different allergenicity of Bet v 1 and Bet v 2.
The Journal of allergy and clinical immunology 1996;98(5 Pt 1):913-21.
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1996: Menz G; Dolecek C; Schönheit-Kenn U; Ferreira F; Moser M; Schneider T; Suter M; Boltz-Nitulescu G; Ebner C; Kraft D; Valenta R
[Serologic and skin test diagnosis of birch pollen allergy with recombinant Bet v 1, the chief allergen of birch]
Pneumologie (Stuttgart, Germany) 1996;50(9):632-40.
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1996: Laffer S; Spitzauer S; Susani M; Pairleitner H; Schweiger C; Grönlund H; Menz G; Pauli G; Ishii T; Nolte H; Ebner C; Sehon A H; Kraft D; Eichler H G; Valenta R
Comparison of recombinant timothy grass pollen allergens with natural extract for diagnosis of grass pollen allergy in different populations.
The Journal of allergy and clinical immunology 1996;98(3):652-8.
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1996: Vrtala S; Wiedemann P; Mittermann I; Eichler H G; Sperr W R; Valent P; Kraft D; Valenta R
High-level expression in Escherichia coli and purification of recombinant plant profilins: comparison of IgE-binding capacity and allergenic activity.
Biochemical and biophysical research communications 1996;226(1):42-50.
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1996: Valenta R; Maurer D; Steiner R; Seiberler S; Sperr W R; Valent P; Spitzauer S; Kapiotis S; Smolen J; Stingl G
Immunoglobulin E response to human proteins in atopic patients.
The Journal of investigative dermatology 1996;107(2):203-8.
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1996: Fischer S; Grote M; Fahlbusch B; Müller W D; Kraft D; Valenta R
Characterization of Phl p 4, a major timothy grass (Phleum pratense) pollen allergen.
The Journal of allergy and clinical immunology 1996;98(1):189-98.
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1996: Visco V; Dolecek C; Denépoux S; Le Mao J; Guret C; Rousset F; Guinnepain M T; Kraft D; Valenta R; Weyer A; Banchereau J; Labecque S
Human IgG monoclonal antibodies that modulate the binding of specific IgE to birch pollen Bet v 1.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):956-62.
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1996: Steinberger P; Kraft D; Valenta R
Construction of a combinatorial IgE library from an allergic patient. Isolation and characterization of human IgE Fabs with specificity for the major timothy grass pollen allergen, Phl p 5.
The Journal of biological chemistry 1996;271(18):10967-72.
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1996: Pauli G; Oster J P; Deviller P; Heiss S; Bessot J C; Susani M; Ferreira F; Kraft D; Valenta R
Skin testing with recombinant allergens rBet v 1 and birch profilin, rBet v 2: diagnostic value for birch pollen and associated allergies.
The Journal of allergy and clinical immunology 1996;97(5):1100-9.
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1996: Valenta R; Steinberger P; Duchêne M; Kraft D
Immunological and structural similarities among allergens: prerequisite for a specific and component-based therapy of allergy.
Immunology and cell biology 1996;74(2):187-94.
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1996: Valenta R; Kraft D
Type 1 allergic reactions to plant-derived food: a consequence of primary sensitization to pollen allergens.
The Journal of allergy and clinical immunology 1996;97(4):893-5.
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1996: Laffer S; Duchene M; Reimitzer I; Susani M; Mannhalter C; Kraft D; Valenta R
Common IgE-epitopes of recombinant Phl p I, the major timothy grass pollen allergen and natural group I grass pollen isoallergens.
Molecular immunology 1996;33(4-5):417-26.
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1996: Vrtala S; Susani M; Sperr W R; Valent P; Laffer S; Dolecek C; Kraft D; Valenta R
Immunologic characterization of purified recombinant timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p2, Phl p 5).
The Journal of allergy and clinical immunology 1996;97(3):781-7.
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1996: Heiss S; Flicker S; Hamilton D A; Kraft D; Mascarenhas J P; Valenta R
Expression of Zm13, a pollen specific maize protein, in Escherichia coli reveals IgE-binding capacity and allergenic potential.
FEBS letters 1996;381(3):217-21.
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1996: Rothkegel M; Mayboroda O; Rohde M; Wucherpfennig C; Valenta R; Jockusch B M
Plant and animal profilins are functionally equivalent and stabilize microfilaments in living animal cells.
Journal of cell science 1996;109 ( Pt 1)():83-90.
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1996: Menz G; Dolecek C; Schönheit-Kenn U; Ferreira F; Moser M; Schneider T; Suter M; Boltz-Nitulescu G; Ebner C; Kraft D; Valenta R
Serological and skin-test diagnosis of birch pollen allergy with recombinant Bet v I, the major birch pollen allergen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(1):50-60.
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1996: Ferreira F D; Mayer P; Sperr W R; Valent P; Seiberler S; Ebner C; Liehl E; Scheiner O; Kraft D; Valenta R
Induction of IgE antibodies with predefined specificity in rhesus monkeys with recombinant birch pollen allergens, Bet v 1 and Bet v 2.
The Journal of allergy and clinical immunology 1996;97(1 Pt 1):95-103.
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1996: Valenta R; Laffer S; Vrtala S; Grönlund H; Elfman L; Sperr W R; Valent P; Ferreira F; Mayer P; Liehl E; Heiss S; Steiner R; Eichler H G; Susani M; Kraft D
Recombinant allergens. Steps on the way to diagnosis and therapy of type I allergy.
Advances in experimental medicine and biology 1996;409():185-96.
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1996: Schenk S; Breiteneder H; Susani M; Najafian N; Laffer S; Duchêne M; Valenta R; Fischer G; Scheiner O; Kraft D; Ebner C
T cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense). Crossreactivity with group I allergens of different grasses.
Advances in experimental medicine and biology 1996;409():141-6.
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1996: Ebner C; Hirschwehr R; Bauer L; Breiteneder H; Valenta R; Hoffmann K; Krebitz M; Kraft D; Scheiner O
Identification of allergens in apple, pear, celery, carrot and potato: cross-reactivity with pollen allergens.
Monographs in allergy 1996;32():73-7.
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1995: Hess M W; Mittermann I; Luschnig C; Valenta R
Immunocytochemical localisation of actin and profilin in the generative cell of angiosperm pollen: TEM studies on high-pressure frozen and freeze-substituted Ledebouria socialis Roth (Hyacinthaceae).
Histochemistry and cell biology 1995;104(6):443-51.
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1995: Valenta R; Kraft D
Recombinant allergens for diagnosis and therapy of allergic diseases.
Current opinion in immunology 1995;7(6):751-6.
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1995: Schenk S; Breiteneder H; Susani M; Najafian N; Laffer S; Duchêne M; Valenta R; Fischer G; Scheiner O; Kraft D
T-cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense): evidence for crossreacting and non-crossreacting T-cell epitopes within grass group I allergens.
The Journal of allergy and clinical immunology 1995;96(6 Pt 1):986-96.
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1995: Spitzauer S; Pandjaitan B; Söregi G; Mühl S; Ebner C; Kraft D; Valenta R; Rumpold H
IgE cross-reactivities against albumins in patients allergic to animals.
The Journal of allergy and clinical immunology 1995;96(6 Pt 1):951-9.
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1995: Binder M; Ortner S; Erben H; Scheiner O; Wiedermann G; Valenta R; Duchêne M
The basic isoform of profilin in pathogenic Entamoeba histolytica. cDNA cloning, heterologous expression, and actin-binding properties.
European journal of biochemistry / FEBS 1995;233(3):976-81.
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1995: Susani M; Jertschin P; Dolecek C; Sperr W R; Valent P; Ebner C; Kraft D; Valenta R; Scheiner O
High level expression of birch pollen profilin (Bet v 2) in Escherichia coli: purification and characterization of the recombinant allergen.
Biochemical and biophysical research communications 1995;215(1):250-63.
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1995: Dolecek C; Steinberger P; Susani M; Kraft D; Valenta R; Boltz-Nitulescu G
Effects of IL-4 and IL-13 on total and allergen specific IgE production by cultured PBMC from allergic patients determined with recombinant pollen allergens.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25(9):879-89.
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1995: Steinberger P; Bohle B; di Padova F; Wrann M; Liehl E; Scheiner O; Kraft D; Valenta R
Allergen-specific IgE production of committed B cells from allergic patients in vitro.
The Journal of allergy and clinical immunology 1995;96(2):209-18.
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1995: Ebner C; Hirschwehr R; Bauer L; Breiteneder H; Valenta R; Ebner H; Kraft D; Scheiner O
Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin).
The Journal of allergy and clinical immunology 1995;95(5 Pt 1):962-9.
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1995: Vrtala S; Grote M; Ferreira F; Susani M; Stocker B; Kraft D; Valenta R
Humoral immune responses to recombinant tree pollen allergens (Bet v I and Bet v II) in mice: construction of a live oral allergy vaccine.
International archives of allergy and immunology 1995;107(1-3):290-4.
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1995: Vallier P; Balland S; Harf R; Valenta R; Deviller P
Identification of profilin as an IgE-binding component in latex from Hevea brasiliensis: clinical implications.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25(4):332-9.
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1995: Mittermann I; Swoboda I; Pierson E; Eller N; Kraft D; Valenta R; Heberle-Bors E
Molecular cloning and characterization of profilin from tobacco (Nicotiana tabacum): increased profilin expression during pollen maturation.
Plant molecular biology 1995;27(1):137-46.
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1994: Giehl K; Valenta R; Rothkegel M; Ronsiek M; Mannherz H G; Jockusch B M
Interaction of plant profilin with mammalian actin.
European journal of biochemistry / FEBS 1994;226(2):681-9.
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1994: Ball T; Vrtala S; Sperr W R; Valent P; Susani M; Kraft D; Valenta R
Isolation of an immunodominant IgE hapten from an epitope expression cDNA library. Dissection of the allergic effector reaction.
The Journal of biological chemistry 1994;269(45):28323-8.
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1994: Laffer S; Valenta R; Vrtala S; Susani M; van Ree R; Kraft D; Scheiner O; Duchêne M
Complementary DNA cloning of the major allergen Phl p I from timothy grass (Phleum pratense); recombinant Phl p I inhibits IgE binding to group I allergens from eight different grass species.
The Journal of allergy and clinical immunology 1994;94(4):689-98.
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1994: Seiberler S; Scheiner O; Kraft D; Lonsdale D; Valenta R
Characterization of a birch pollen allergen, Bet v III, representing a novel class of Ca2+ binding proteins: specific expression in mature pollen and dependence of patients' IgE binding on protein-bound Ca2+.
The EMBO journal 1994;13(15):3481-6.
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1994: Laffer S; Vrtala S; Duchêne M; van Ree R; Kraft D; Scheiner O; Valenta R
IgE-binding capacity of recombinant timothy grass (Phleum pratense) pollen allergens.
The Journal of allergy and clinical immunology 1994;94(1):88-94.
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1994: Grote M; Dolecek C; Van Ree R; Valenta R
Immunogold electron microscopic localization of timothy grass (Phleum pratense) pollen major allergens Phl p I and Phl p V after anhydrous fixation in acrolein vapor.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1994;42(3):427-31.
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1994: Valenta R; Ball T; Vrtala S; Duchêne M; Kraft D; Scheiner O
cDNA cloning and expression of timothy grass (Phleum pratense) pollen profilin in Escherichia coli: comparison with birch pollen profilin.
Biochemical and biophysical research communications 1994;199(1):106-18.
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1994: Valenta R; Vrtala S; Laffer S; Steinberger P; Ball T; Ferreira F; Scheiner O; Kraft D
B-cell epitopes of allergens determined by recombinant techniques; use for diagnosis and therapy of type I allergy.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 1994;(87):235-46.
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1994: Scheiner O; Breiteneder H; Dolocek C; Duchêne M; Ebner C; Ferreira F; Hoffmann K; Schenk S; Valenta R; Kraft D
Molecular and functional characterization of allergens: basic and practical aspects.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 1994;(87):221-32; discussion 233-4.
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1993: Dolecek C; Vrtala S; Laffer S; Steinberger P; Kraft D; Scheiner O; Valenta R
Molecular characterization of Phl p II, a major timothy grass (Phleum pratense) pollen allergen.
FEBS letters 1993;335(3):299-304.
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1993: Valenta R; Ferreira F; Grote M; Swoboda I; Vrtala S; Duchêne M; Deviller P; Meagher R B; McKinney E; Heberle-Bors E
Identification of profilin as an actin-binding protein in higher plants.
The Journal of biological chemistry 1993;268(30):22777-81.
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1993: Hirschwehr R; Jäger S; Horak F; Ferreira F; Valenta R; Ebner C; Kraft D; Scheiner O
Allergens from birch pollen and pollen of the European chestnut share common epitopes.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1993;23(9):755-61.
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1993: Grote M; Vrtala S; Valenta R
Monitoring of two allergens, Bet v I and profilin, in dry and rehydrated birch pollen by immunogold electron microscopy and immunoblotting.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1993;41(5):745-50.
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1993: Ebner C; Szépfalusi Z; Ferreira F; Jilek A; Valenta R; Parronchi P; Maggi E; Romagnani S; Scheiner O; Kraft D
Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(3):1047-54.
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1993: Valenta R; Sperr W R; Ferreira F; Valent P; Sillaber C; Tejkl M; Duchêne M; Ebner C; Lechner K; Kraft D
Induction of specific histamine release from basophils with purified natural and recombinant birch pollen allergens.
The Journal of allergy and clinical immunology 1993;91(1 Pt 1):88-97.
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1993: Vrtala S; Grote M; Duchêne M; van Ree R; Kraft D; Scheiner O; Valenta R
Properties of tree and grass pollen allergens: reinvestigation of the linkage between solubility and allergenicity.
International archives of allergy and immunology 1993;102(2):160-9.
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1993: Valenta R; Steinberger P; Vrtala S; Grote M; Laffer S; Sperr W R; Valent P; Kraft D; Scheiner O
[New concepts in therapy of type I allergic diseases]
Wiener klinische Wochenschrift 1993;105(23):682-6.
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1992: Breiteneder H; Ferreira F; Reikerstorfer A; Duchene M; Valenta R; Hoffmann-Sommergruber K; Ebner C; Breitenbach M; Kraft D; Scheiner O
Complementary DNA cloning and expression in Escherichia coli of Aln g I, the major allergen in pollen of alder (Alnus glutinosa).
The Journal of allergy and clinical immunology 1992;90(6 Pt 1):909-17.
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1992: Hirschwehr R; Valenta R; Ebner C; Ferreira F; Sperr W R; Valent P; Rohac M; Rumpold H; Scheiner O; Kraft D
Identification of common allergenic structures in hazel pollen and hazelnuts: a possible explanation for sensitivity to hazelnuts in patients allergic to tree pollen.
The Journal of allergy and clinical immunology 1992;90(6 Pt 1):927-36.
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1992: Pettenburger K; Tejkl M; Valenta R; Hoffmann-Sommergruber K; Swoboda I; Heberle-Bors E; Breitenbach M; Rumpold H; Kraft D; Scheiner O
Distribution of allergens and allergen-coding mRNAs in various tissues of white birch.
Molecular immunology 1992;29(11):1401-6.
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1992: Vallier P; DeChamp C; Valenta R; Vial O; Deviller P
Purification and characterization of an allergen from celery immunochemically related to an allergen present in several other plant species. Identification as a profilin.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(8):774-82.
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1992: Valenta R; Duchene M; Ebner C; Valent P; Sillaber C; Deviller P; Ferreira F; Tejkl M; Edelmann H; Kraft D
Profilins constitute a novel family of functional plant pan-allergens.
The Journal of experimental medicine 1992;175(2):377-85.
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1992: Valenta R; Vrtala S; Ebner C; Kraft D; Scheiner O
Diagnosis of grass pollen allergy with recombinant timothy grass (Phleum pratense) pollen allergens.
International archives of allergy and immunology 1992;97(4):287-94.
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1992: Plaimauer B; Ortner S; Födinger M; Binder M; Wiedermann G; Kraft D; Scheiner O; Valenta R; Duchêne M
Molecular characterization of IgG and IgE antigens of Entamoeba histolytica.
Archives of medical research 1992;23(2):255-7.
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1991: Valenta R; Duchene M; Vrtala S; Birkner T; Ebner C; Hirschwehr R; Breitenbach M; Rumpold H; Scheiner O; Kraft D
Recombinant allergens for immunoblot diagnosis of tree-pollen allergy.
The Journal of allergy and clinical immunology 1991;88(6):889-94.
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1991: Ebner C; Birkner T; Valenta R; Rumpold H; Breitenbach M; Scheiner O; Kraft D
Common epitopes of birch pollen and apples--studies by western and northern blot.
The Journal of allergy and clinical immunology 1991;88(4):588-94.
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1991: Valenta R; Duchêne M; Pettenburger K; Sillaber C; Valent P; Bettelheim P; Breitenbach M; Rumpold H; Kraft D; Scheiner O
Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals.
Science (New York, N.Y.) 1991;253(5019):557-60.
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1991: Valenta R; Breiteneder H; Petternburger K; Breitenbach M; Rumpold H; Kraft D; Scheiner O
Homology of the major birch-pollen allergen, Bet v I, with the major pollen allergens of alder, hazel, and hornbeam at the nucleic acid level as determined by cross-hybridization.
The Journal of allergy and clinical immunology 1991;87(3):677-82.
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1991: Valenta R; Duchêne M; Breitenbach M; Pettenburger K; Koller L; Rumpold H; Scheiner O; Kraft D
A low molecular weight allergen of white birch (Betula verrucosa) is highly homologous to human profilin.
International archives of allergy and applied immunology 1991;94(1-4):368-70.
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1991: Spitzauer S; Rumpold H; Ebner C; Schweiger C; Valenta R; Gabl F; Anrather J; Breitenbach M; Scheiner O; Kraft D
Allergen profiles of dog hair and dander, body fluids and tissues as defined by immunoblotting.
International archives of allergy and applied immunology 1991;94(1-4):346-8.
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1989: Breiteneder H; Pettenburger K; Bito A; Valenta R; Kraft D; Rumpold H; Scheiner O; Breitenbach M
The gene coding for the major birch pollen allergen Betv1, is highly homologous to a pea disease resistance response gene.
The EMBO journal 1989;8(7):1935-8.
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