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Dennis Bourdette

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Rebecca Spain; R J St George; J M Wagner; Fay B Horak; M Mancini; Arash Salarian; Dennis N Bourdette
Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed.
Vijayshree Yadav; Christopher Bever Jr; Dennis N Bourdette; James D Bowen; Gregory G Burrows; Al J Ferro; Andrew Goldstein; Sharon G Lynch; David Mattson; Halina Offner; Jana Preiningerova; Jack Simon; Arthur A Vandenbark
Recombinant T-Cell Receptor Ligand (RTL) for Treatment of Multiple Sclerosis: A Double-Blind, Placebo-Controlled, Phase 1, Dose-Escalation Study.
E Kim; Jesus Lovera; L Schaben; Dennis N Bourdette; M Cameron; Ruth H Whitham
American ginseng does not improve fatigue in multiple sclerosis: a single center randomized double-blind placebo-controlled crossover pilot study.

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2012: Rebecca Spain; R J St George; J M Wagner; Fay B Horak; M Mancini; Arash Salarian; Dennis N Bourdette
Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed.
Gait & posture 2012;35(4):573-8.
2012: Vijayshree Yadav; Christopher Bever Jr; Dennis N Bourdette; James D Bowen; Gregory G Burrows; Al J Ferro; Andrew Goldstein; Sharon G Lynch; David Mattson; Halina Offner; Jana Preiningerova; Jack Simon; Arthur A Vandenbark
Recombinant T-Cell Receptor Ligand (RTL) for Treatment of Multiple Sclerosis: A Double-Blind, Placebo-Controlled, Phase 1, Dose-Escalation Study.
Autoimmune diseases 2012;2012():954739.
2011: E Kim; Jesus Lovera; L Schaben; Dennis N Bourdette; M Cameron; Ruth H Whitham
American ginseng does not improve fatigue in multiple sclerosis: a single center randomized double-blind placebo-controlled crossover pilot study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(12):1523-6.
2011: Vijayshree Yadav; Dennis N Bourdette
Cognitive impairment and MS: searching for effective therapies.
Current neurology and neuroscience reports 2011;11(5):451-4.
2011: Michael K Axthelm; Dennis N Bourdette; Steven G Kohama; Minsha Manoharan; Gail H Marracci; Elizabeth T Mullaney; Jim Pollaro; William D Rooney; Larry S Sherman; Weiping Su; Paul Wang; Ellen Witkowski; Scott W Wong
Japanese macaque encephalomyelitis: a spontaneous multiple sclerosis-like disease in a nonhuman primate.
Annals of neurology 2011;70(3):362-73.
2011: Sonemany Salinthone; Robynn V Schillace; Catherine Tsang; Dennis N Bourdette; John W Regan; Daniel W Carr
Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms.
The Journal of nutritional biochemistry 2011;22(7):681-90.
2011: D M Miller; Dennis N Bourdette; P Foulds; Bianca Weinstock-Guttman; X You; R A Rudick
Change in quality of life in patients with relapsing-remitting multiple sclerosis over 2 years in relation to other clinical parameters: results from a trial of intramuscular interferon {beta}-1a.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(6):734-42.
2011: Priya Chaudhary; Gail H Marracci; Xiaolin Yu; Danielle Galipeau; Brooke Morris; Dennis N Bourdette
Lipoic acid decreases inflammation and confers neuroprotection in experimental autoimmune optic neuritis.
Journal of neuroimmunology 2011;233(1-2):90-6.
2011: Dennis N Bourdette; Vijayshree Yadav
The radiologically isolated syndrome revisited: when is it presymptomatic multiple sclerosis?
Neurology 2011;76(8):680-1.
2011: Michelle H Cameron; Amy J Poel; Jodie K Haselkorn; Alex Linke; Dennis N Bourdette
Falls requiring medical attention among veterans with multiple sclerosis: a cohort study.
Journal of rehabilitation research and development 2011;48(1):13-20.
2010: Richard A Rudick; Jar-Chi Lee; Gary R Cutter; Deborah M Miller; Dennis N Bourdette; Bianca Weinstock-Guttman; Robert Hyde; Hao Zhang; Xiaojun You
Disability progression in a clinical trial of relapsing-remitting multiple sclerosis: eight-year follow-up.
Archives of neurology 2010;67(11):1329-35.
2010: Vijayshree Yadav; Dennis N Bourdette
Oral disease-modifying therapies for multiple sclerosis: are we there yet?
Current neurology and neuroscience reports 2010;10(5):333-5.
2010: J F Lovera; E Frohman; T R Brown; D Bandari; L Nguyen; Vijayshree Yadav; O Stuve; J Karman; K Bogardus; G Heimburger; L Cua; G Remingon; J Fowler; T Monahan; S Kilcup; Y Courtney; J McAleenan; K Butler; Katherine Wild; Ruth H Whitham; Dennis N Bourdette
Memantine for cognitive impairment in multiple sclerosis: a randomized placebo-controlled trial.
Multiple sclerosis (Houndmills, Basingstoke, England) 2010;16(6):715-23.
2010: C L Hugos; L F Copperman; B E Fuller; Vijayshree Yadav; Jesus Lovera; Dennis N Bourdette
Clinical trial of a formal group fatigue program in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2010;16(6):724-32.
2010: Michael C Kruer; Thomas K Koch; Dennis N Bourdette; D Chabas; E Waubant; S Mueller; M A Moscarello; J Dalmau; Randall L Woltjer; Grazyna Adamus
NMDA receptor encephalitis mimicking seronegative neuromyelitis optica.
Neurology 2010;74(18):1473-5.
2010: Dennis N Bourdette; Ruth H Whitham
Immunotherapy and multiple sclerosis: The devil is in the details.
Neurology 2010;74(18):1410-1.
2010: Vijayshree Yadav; Lynne Shinto; Dennis N Bourdette
Complementary and alternative medicine for the treatment of multiple sclerosis.
Expert review of clinical immunology 2010;6(3):381-95.
2010: R A Bermel; Bianca Weinstock-Guttman; Dennis N Bourdette; P Foulds; X You; R A Rudick
Intramuscular interferon beta-1a therapy in patients with relapsing-remitting multiple sclerosis: a 15-year follow-up study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2010;16(5):588-96.
2010: Vijayshree Yadav; Gail H Marracci; Myrna Y Munar; Ganesh Cherala; Lauren E Stuber; Lilia Alvarez; Lynne Shinto; Dennis R Koop; Dennis N Bourdette
Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters.
Multiple sclerosis (Houndmills, Basingstoke, England) 2010;16(4):387-97.
2010: Dennis N Bourdette; Edward A Neuwelt; Nancy D Doolittle; Dale Kraemer
Reply.
Annals of neurology 2010;67(2):270-1; author reply 271.
2010: Logan M McDaneld; Jeremy D Fields; Dennis N Bourdette; Anish Bhardwaj
Immunomodulatory therapies in neurologic critical care.
Neurocritical care 2010;12(1):132-43.
2010: M Samantha Lewis; David J Lilly; Michele M Hutter; Dennis N Bourdette; Garnett P McMillan; Mary A Fitzpatrick; Stephen A Fausti
Audiometric hearing status of individuals with and without multiple sclerosis.
Journal of rehabilitation research and development 2010;47(7):669-78.
2010: Sonemany Salinthone; Vijayshree Yadav; Robynn V Schillace; Dennis N Bourdette; Daniel W Carr
Lipoic acid attenuates inflammation via cAMP and protein kinase A signaling.
PloS one 2010;5(9):.
2010: Edward Kim; Jesus Lovera; Laura Schaben; J Melara; Dennis N Bourdette; Ruth H Whitham
Novel method for measurement of fatigue in multiple sclerosis: Real-Time Digital Fatigue Score.
Journal of rehabilitation research and development 2010;47(5):477-84.
2009: Arthur Vandenbark; Jianya Huan; Marisa Agotsch; Dorian La Tocha; Susan Goelz; Halina Offner; Stefan Lanker; Dennis N Bourdette
Interferon-beta-1a treatment increases CD56bright natural killer cells and CD4+CD25+ Foxp3 expression in subjects with multiple sclerosis.
Journal of neuroimmunology 2009;215(1-2):125-8.
2009: Kimmy G Su; Gary Banker; Dennis N Bourdette; Michael Forte
Axonal degeneration in multiple sclerosis: the mitochondrial hypothesis.
Current neurology and neuroscience reports 2009;9(5):411-7.
2009: Dennis N Bourdette; Vijayshree Yadav
Alemtuzumab versus interferon beta-1a in early multiple sclerosis.
Current neurology and neuroscience reports 2009;9(5):341-2.
2009: Dennis N Bourdette; Jack Simon
The radiologically isolated syndrome: is it very early multiple sclerosis?
Neurology 2009;72(9):780-1.
2009: Lynne Shinto; Gail H Marracci; S Baldauf-Wagner; A Strehlow; Vijayshree Yadav; L Stuber; Dennis N Bourdette
Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis.
Prostaglandins, leukotrienes, and essential fatty acids 2009;80(2-3):131-6.
2009: Bridget A Bagert; Dennis N Bourdette
New oral disease-modifying therapies for multiple sclerosis.
F1000 medicine reports 2009;1():.
2009: Rebecca Spain; Michelle Cameron; Dennis N Bourdette
Recent developments in multiple sclerosis therapeutics.
BMC medicine 2009;7():74.
2008: Dennis N Bourdette; Vijayshree Yadav
B-cell depletion with rituximab in relapsing-remitting multiple sclerosis.
Current neurology and neuroscience reports 2008;8(5):417-8.
2008: Sonemany Salinthone; Robynn V Schillace; Gail H Marracci; Dennis N Bourdette; Daniel W Carr
Lipoic acid stimulates cAMP production via the EP2 and EP4 prostanoid receptors and inhibits IFN gamma synthesis and cellular cytotoxicity in NK cells.
Journal of neuroimmunology 2008;199(1-2):46-55.
2008: Sonemany Salinthone; Vijayshree Yadav; Dennis N Bourdette; Daniel W Carr
Lipoic acid: a novel therapeutic approach for multiple sclerosis and other chronic inflammatory diseases of the CNS.
Endocrine, metabolic & immune disorders drug targets 2008;8(2):132-42.
2008: Lynne Shinto; Carlo Calabrese; Cynthia Morris; Vijayshree Yadav; Debbie Griffith; Rachel Frank; Barry S Oken; Sara Baldauf-Wagner; Dennis N Bourdette
A randomized pilot study of naturopathic medicine in multiple sclerosis.
Journal of alternative and complementary medicine (New York, N.Y.) 2008;14(5):489-96.
2008: Michelle Cameron; Marina Soares; Robert R Herndon; Dennis N Bourdette
Imbalance in multiple sclerosis: a result of slowed spinal somatosensory conduction.
Somatosensory & motor research 2008;25(2):113-22.
2008: Arthur Vandenbark; Nicole Culbertson; Richard Bartholomew; Jianya Huan; Marci Agotsch; Dorian LaTocha; Vijayshree Yadav; Michele K Mass; Ruth H Whitham; Jesus Lovera; June Milano; Georgia Theofan; Yuan K Chou; Halina Offner; Dennis N Bourdette
Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis.
Immunology 2008;123(1):66-78.
2007: Michael Forte; Bruce G Gold; Gail H Marracci; Priya Chaudhary; Emy Basso; Dustin Johnsen; Xiaolin Yu; Jonathan Fowlkes; Micha Rahder; Katie Stem; Paolo Bernardi; Dennis N Bourdette
Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7558-63.
2007: Jesus Lovera; Bridget Bagert; K Smoot; Cynthia Morris; R Frank; Kristin Bogardus; Katherine Wild; Barry S Oken; Ruth H Whitham; Dennis N Bourdette
Ginkgo biloba for the improvement of cognitive performance in multiple sclerosis: a randomized, placebo-controlled trial.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(3):376-85.
2007: Robynn V Schillace; N Pisenti; N Pattamanuch; Sarah G Galligan; Gail H Marracci; Dennis N Bourdette; Daniel W Carr
Lipoic acid stimulates cAMP production in T lymphocytes and NK cells.
Biochemical and biophysical research communications 2007;354(1):259-64.
2007: Abigail C Buenafe; Dennis N Bourdette
Lipopolysaccharide pretreatment modulates the disease course in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2007;182(1-2):32-40.
2006: M Samantha Lewis; Michele Hutter; David J Lilly; Dennis N Bourdette; Julie Saunders; Stephen A Fausti
Frequency-modulation (FM) technology as a method for improving speech perception in noise for individuals with multiple sclerosis.
Journal of the American Academy of Audiology 2006;17(8):605-16.
2006: Chunhe Wang; Bruce G Gold; Laurie J Kaler; Xiaolin Yu; Michael Afentoulis; Gregory G Burrows; Arthur Vandenbark; Dennis N Bourdette; Halina Offner
Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE.
Journal of neurochemistry 2006;98(6):1817-27.
2006: Gail H Marracci; Whitney E Marquardt; Adrienne Strehlow; Gabriel P McKeon; Jonathan Gross; David C Buck; Laura B Kozell; Dennis N Bourdette
Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck).
Biochemical and biophysical research communications 2006;344(3):963-71.
2006: Priya Chaudhary; Gail H Marracci; Dennis N Bourdette
Lipoic acid inhibits expression of ICAM-1 and VCAM-1 by CNS endothelial cells and T cell migration into the spinal cord in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2006;175(1-2):87-96.
2006: Vijayshree Yadav; Dennis N Bourdette
Complementary and alternative medicine: is there a role in multiple sclerosis?
Current neurology and neuroscience reports 2006;6(3):259-67.
2006: Lynne Shinto; Vijayshree Yadav; Cynthia Morris; Jodi A Lapidus; A Senders; Dennis N Bourdette
Demographic and health-related factors associated with complementary and alternative medicine (CAM) use in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2006;12(1):94-100.
2006: M Samantha Lewis; David J Lilly; Michele Hutter; Dennis N Bourdette; Julie Saunders; Stephen A Fausti
Some effects of multiple sclerosis on speech perception in noise: Preliminary findings.
Journal of rehabilitation research and development 2006;43(1):91-8.
2006: Barry S Oken; Kristin Flegal; Daniel Zajdel; Shirley S Kishiyama; Jesus Lovera; Bridget Bagert; Dennis N Bourdette
Cognition and fatigue in multiple sclerosis: Potential effects of medications with central nervous system activity.
Journal of rehabilitation research and development 2006;43(1):83-90.
2006: Jesus Lovera; Bridget Bagert; Kyle H Smoot; Katherine Wild; Rachel Frank; Kristin Bogardus; Barry S Oken; Ruth H Whitham; Dennis N Bourdette
Correlations of Perceived Deficits Questionnaire of Multiple Sclerosis Quality of Life Inventory with Beck Depression Inventory and neuropsychological tests.
Journal of rehabilitation research and development 2006;43(1):73-82.
2006: Aaron Turner; Christine Martin; Rhonda M Williams; Kelly Goudreau; James D Bowen; Michael Hatzakis; Ruth H Whitham; Dennis N Bourdette; Lynne Walker; Jodie K Haselkorn
Exploring educational needs of multiple sclerosis care providers: Results of a care-provider survey.
Journal of rehabilitation research and development 2006;43(1):25-34.
2005: Lynne Shinto; Vijayshree Yadav; Cynthia Morris; Jodi A Lapidus; A Senders; Dennis N Bourdette
The perceived benefit and satisfaction from conventional and complementary and alternative medicine (CAM) in people with multiple sclerosis.
Complementary therapies in medicine 2005;13(4):264-72.
2005: Dennis N Bourdette; E Edmonds; Craig H Smith; J D Bowen; C R G Guttmann; Z P Nagy; J Simon; Ruth H Whitham; Jesus Lovera; Vijayshree Yadav; Michele K Mass; L Spencer; Nicole Culbertson; Richard Bartholomew; Georgia Theofan; J Milano; Halina Offner; Arthur Vandenbark
A highly immunogenic trivalent T cell receptor peptide vaccine for multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2005;11(5):552-61.
2005: Amala Soumyanath; Yong-Ping Zhong; Sandra A Gold; Xiaolin Yu; Dennis R Koop; Dennis N Bourdette; Bruce G Gold
Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.
The Journal of pharmacy and pharmacology 2005;57(9):1221-9.
2005: Jianya Huan; Nicole Culbertson; Leslie Spencer; Richard Bartholomew; Gregory G Burrows; Yuan K Chou; Dennis N Bourdette; Steven F Ziegler; Halina Offner; Arthur Vandenbark
Decreased FOXP3 levels in multiple sclerosis patients.
Journal of neuroscience research 2005;81(1):45-52.
2005: Vijayshree Yadav; Gail H Marracci; Jesus Lovera; W Woodward; Kristin Bogardus; W Marquardt; Lynne Shinto; Cynthia Morris; Dennis N Bourdette
Lipoic acid in multiple sclerosis: a pilot study.
Multiple sclerosis (Houndmills, Basingstoke, England) 2005;11(2):159-65.
2004: Bruce A C Cree; OA Khan; Dennis N Bourdette; Douglas Goodin; J A Cohen; R A Marrie; D Glidden; B Weinstock-Guttman; D Reich; N Patterson; Jonathan L Haines; Margaret Pericak-Vance; Cari DeLoa; Jorge R Oksenberg; Stephen L Hauser
Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis.
Neurology 2004;63(11):2039-45.
2004: Gail H Marracci; Gabriel P McKeon; Whitney E Marquardt; Rolf Winter; Michael K Riscoe; Dennis N Bourdette
Alpha lipoic acid inhibits human T-cell migration: implications for multiple sclerosis.
Journal of neuroscience research 2004;78(3):362-70.
2004: Lynne Shinto; Carlo Calabrese; Cynthia Morris; Shannon Sinsheimer; Dennis N Bourdette
Complementary and alternative medicine in multiple sclerosis: survey of licensed naturopaths.
Journal of alternative and complementary medicine (New York, N.Y.) 2004;10(5):891-7.
2004: Yuan K Chou; Nicole Culbertson; Cathleen Rich; Dorian LaTocha; Abigail C Buenafe; Jianya Huan; Jason Link; J M Wands; Willi K Born; Halina Offner; Dennis N Bourdette; Gregory G Burrows; Arthur Vandenbark
T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice.
Journal of neuroscience research 2004;77(5):670-80.
2004: Bruce G Gold; Jan Voda; Xiaolin Yu; Gabriel P McKeon; Dennis N Bourdette
FK506 and a nonimmunosuppressant derivative reduce axonal and myelin damage in experimental autoimmune encephalomyelitis: neuroimmunophilin ligand-mediated neuroprotection in a model of multiple sclerosis.
Journal of neuroscience research 2004;77(3):367-77.
2004: Barry S Oken; Shirley S Kishiyama; Daniel Zajdel; Dennis N Bourdette; J Carlsen; Mitchell Haas; C Hugos; Dale F Kraemer; J Lawrence; Michele K Mass
Randomized controlled trial of yoga and exercise in multiple sclerosis.
Neurology 2004;62(11):2058-64.
2004: Bruce G Gold; Esther Udina; Dennis N Bourdette; Xavier Navarro
Neuroregenerative and neuroprotective actions of neuroimmunophilin compounds in traumatic and inflammatory neuropathies.
Neurological research 2004;26(4):371-80.
2004: Abigail C Buenafe; Laura Tsaknaridis; Leslie Spencer; Kevin S Hicks; Rachel H McMahan; Lisa Watson; Nicole Culbertson; Dorian LaTocha; Keith Wegmann; Tom Finn; Richard Bartholomew; Gregory G Burrows; Ruth H Whitham; Dennis N Bourdette; Richard Jones; Halina Offner; Yuan K Chou; Arthur Vandenbark
Specificity of regulatory CD4+CD25+ T cells for self-T cell receptor determinants.
Journal of neuroscience research 2004;76(1):129-40.
2004: Jianya Huan; Sandhya Subramanian; Richard Jones; Cathleen Rich; Jason Link; Jeff Mooney; Dennis N Bourdette; Arthur Vandenbark; Gregory G Burrows; Halina Offner
Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4556-66.
2004: Yuan K Chou; Gregory G Burrows; Dorian LaTocha; Chunhe Wang; Sandhya Subramanian; Dennis N Bourdette; Arthur Vandenbark
CD4 T-cell epitopes of human alpha B-crystallin.
Journal of neuroscience research 2004;75(4):516-23.
2003: Laura Tsaknaridis; Leslie Spencer; Nicole Culbertson; Kevin Hicks; Dorian LaTocha; Yuan K Chou; Ruth H Whitham; Antony C (Tony) Bakke; Richard Jones; Halina Offner; Dennis N Bourdette; Arthur Vandenbark
Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity.
Journal of neuroscience research 2003;74(2):296-308.
2003: Agata Matejuk; Corwyn Hopke; Jami Dwyer; Sandhya Subramanian; Richard Jones; Dennis N Bourdette; Arthur Vandenbark; Halina Offner
CNS gene expression pattern associated with spontaneous experimental autoimmune encephalomyelitis.
Journal of neuroscience research 2003;73(5):667-78.
2003: Rachel H McMahan; Lisa Watson; Roberto Meza-Romero; Gregory G Burrows; Dennis N Bourdette; Abigail C Buenafe
Production, characterization, and immunogenicity of a soluble rat single chain T cell receptor specific for an encephalitogenic peptide.
The Journal of biological chemistry 2003;278(33):30961-70.
2003: Scott C Foster; Crystal Daniels; Dennis N Bourdette; Bruce F Bebo
Dysregulation of the hypothalamic-pituitary-gonadal axis in experimental autoimmune encephalomyelitis and multiple sclerosis.
Journal of neuroimmunology 2003;140(1-2):78-87.
2003: Richard Jones; Dennis N Bourdette; Nicole Moes; Arthur Vandenbark; Alex Zamora; Halina Offner
Epitope spreading is not required for relapses in experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1690-8.
2003: Richard Jones; Thomas Kay; Thomas Keller; Dennis N Bourdette
Nonmyelin-specific T cells accelerate development of central nervous system APC and increase susceptibility to experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):831-7.
2002: Gail H Marracci; Richard Jones; Gabriel P McKeon; Dennis N Bourdette
Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2002;131(1-2):104-14.
2002: Dennis N Bourdette
Depression is a treatable cause of suffering among multiple sclerosis patients and can result in suicide.
Neurology 2002;59(5):E6-7.
2002: Linda A McCauley; Sandra K Joos; AndrÃ© Barkhuizen; Tomas Shuell; Wesley A Tyree; Dennis N Bourdette
Chronic fatigue in a population-based study of Gulf War veterans.
Archives of environmental health 2002;57(4):340-8.
2002: Bridget Bagert; Patricia Camplair; Dennis N Bourdette
Cognitive dysfunction in multiple sclerosis: natural history, pathophysiology and management.
CNS drugs 2002;16(7):445-55.
2001: Richard A Rudick; Donald Goodkin; Lawrence D Jacobs; Diane L Cookfair; Robert M Herndon; John R Richert; AM Salazar; Jill Fischer; CV Granger; Jack H Simon; J J Alam; Nancy Simonian; MK Campion; DM Bartoszak; Dennis N Bourdette; J Braiman; Carol Brownscheidle; Michael E Coats; Stanley L Cohan; DS Dougherty; R Philip Kinkel; Michele K Mass; Frederick Munschauer; Roger Priore; P M Pullicino; B J Scherokman; B Weistock-Guttman; Ruth H Whitham
Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis. 1997.
Neurology 2001;57(12 Suppl 5):S25-30.
2001: Dennis N Bourdette; Linda A McCauley; AndrÃ© Barkhuizen; W Johnston; M Wynn; Sandra K Joos; Daniel Storzbach; Tomas Shuell; Diana Sticker
Symptom factor analysis, clinical findings, and functional status in a population-based case control study of Gulf War unexplained illness.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2001;43(12):1026-40.
2001: Arthur Vandenbark; Tom Finn; D Barnes; Nicole Culbertson; Yuan K Chou; K Hicks; Antony C (Tony) Bakke; Michele K Mass; Ruth H Whitham; Halina Offner; Dennis N Bourdette
Diminished frequency of interleukin-10-secreting, T-cell receptor peptide-reactive T cells in multiple sclerosis patients might allow expansion of activated memory T cells bearing the cognate BV gene.
Journal of neuroscience research 2001;66(2):171-6.
2001: Gregory G Burrows; Yuan K Chou; Chunhe Wang; J W Chang; Tom Finn; Nicole Culbertson; J Kim; Dennis N Bourdette; Deborah A Lewinsohn; David M Lewinsohn; M Ikeda; T Yoshioka; Charles N Allen; Halina Offner; Arthur Vandenbark
Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4386-95.
2001: Arthur Vandenbark; E Morgan; Richard Bartholomew; Dennis N Bourdette; Ruth H Whitham; D Carlo; D Gold; G Hashim; Halina Offner
TCR peptide therapy in human autoimmune diseases.
Neurochemical research 2001;26(6):713-30.
2001: Sandhya Subramanian; Dennis N Bourdette; Christopher L Corless; Arthur Vandenbark; Halina Offner; Richard Jones
T lymphocytes promote the development of bone marrow-derived APC in the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):370-6.
2000: Jill Fischer; Roger Priore; Lawrence D Jacobs; Diane L Cookfair; Richard A Rudick; Robert M Herndon; John R Richert; AM Salazar; Donald Goodkin; CV Granger; Jack H Simon; J H Grafman; M D Lezak; K M O'Reilly Hovey; K K Perkins; D Barilla-Clark; M Schacter; D W Shucard; A L Davidson; Karl E Wende; Dennis N Bourdette; Mariska Kooijmans-Coutinho
Neuropsychological effects of interferon beta-1a in relapsing multiple sclerosis. Multiple Sclerosis Collaborative Research Group.
Annals of neurology 2000;48(6):885-92.
2000: Arthur Vandenbark; D Barnes; Tom Finn; Dennis N Bourdette; Ruth H Whitham; I Robey; J Kaleeba; Bruce F Bebo; S D Miller; Halina Offner; Yuan K Chou
Differential susceptibility of human T(h)1 versus T(h) 2 cells to induction of anergy and apoptosis by ECDI/antigen-coupled antigen-presenting cells.
International immunology 2000;12(1):57-66.
1999: Linda A McCauley; Sandra K Joos; Michael Lasarev; Daniel Storzbach; Dennis N Bourdette
Gulf War unexplained illnesses: persistence and unexplained nature of self-reported symptoms.
Environmental research 1999;81(3):215-23.
1999: Gregory G Burrows; J W Chang; Hans Peter Bächinger; Dennis N Bourdette; Halina Offner; Arthur Vandenbark
Design, engineering and production of functional single-chain T cell receptor ligands.
Protein engineering 1999;12(9):771-8.
1999: Dennis N Bourdette; J Antel; Henry McFarland; E Montgomery
Monitoring relapsing remitting MS patients.
Journal of neuroimmunology 1999;98(1):16-21.
1999: Yuan K Chou; Dennis N Bourdette; D Barnes; Tom Finn; S Murray; L Unsicker; I Robey; Ruth H Whitham; Abigail C Buenafe; M Allegretta; Halina Offner; Arthur Vandenbark
IL-7 enhances Ag-specific human T cell response by increasing expression of IL-2R alpha and gamma chains.
Journal of neuroimmunology 1999;96(1):101-11.
1999: Richard Jones; Michele K Mass; Dennis N Bourdette
Myelin basic protein-specific T lymphocytes induce chronic relapsing experimental autoimmune encephalomyelitis in lymphocyte-deficient (SCID) mice.
Journal of neuroimmunology 1999;93(1-2):92-101.
1999: Richard A Rudick; Diane L Cookfair; Nancy Simonian; Richard M Ransohoff; John R Richert; Lawrence D Jacobs; Robert M Herndon; AM Salazar; Jill Fischer; CV Granger; Donald Goodkin; Jack H Simon; DM Bartoszak; Dennis N Bourdette; J Braiman; Carol Brownscheidle; Michael E Coats; Stanley L Cohan; DS Dougherty; R Philip Kinkel; Michele K Mass; F E Munchsauer; K O'Reilly; Roger Priore; Ruth H Whitham
Cerebrospinal fluid abnormalities in a phase III trial of Avonex (IFNbeta-1a) for relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group.
Journal of neuroimmunology 1999;93(1-2):8-14.
1998: Peter S Spencer; Linda A McCauley; Sandra K Joos; Michael Lasarev; T Schuell; Dennis N Bourdette; AndrÃ© Barkhuizen; W Johnston; Daniel Storzbach; M Wynn; R Grewenow
U.S. Gulf War Veterans: service periods in theater, differential exposures, and persistent unexplained illness. Portland Environmental Hazards Research Centre.
Toxicology letters 1998;102-103():515-21.
1998: Donald Goodkin; Roger Priore; Karl E Wende; MK Campion; Dennis N Bourdette; Robert M Herndon; Jill Fischer; Lawrence D Jacobs; Diane L Cookfair; Richard A Rudick; John R Richert; A M Salazar; CV Granger; Jack H Simon; J J Alam; DM Bartoszak; J Braiman; Carol Brownscheidle; Michael E Coats; Stanley L Cohan; DS Dougherty; R Philip Kinkel; Michele K Mass; Frederick Munschauer; Ruth H Whitham
Comparing the ability of various compositive outcomes to discriminate treatment effects in MS clinical trials. The Multiple Sclerosis Collaborative Research Group (MSCRG).
Multiple sclerosis (Houndmills, Basingstoke, England) 1998;4(6):480-6.
1998: S Murray; Sandhya Subramanian; Dennis N Bourdette; Richard Jones
Simplified method of identifying severe combined immunodeficient (SCID) mice versus non-SCID mice by flow cytometric analysis of peripheral blood.
Cytometry 1998;32(4):274-9.
1998: Dennis N Bourdette; Yuan K Chou; Ruth H Whitham; J Buckner; H J Kwon; Gerald Nepom; Abigail C Buenafe; S A Cooper; M Allegretta; G A Hashim; Halina Offner; Arthur Vandenbark
Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(2):1034-44.
1998: Arthur Vandenbark; Yuan K Chou; Ruth H Whitham; Dennis N Bourdette; Halina Offner
Effects of vaccination with T cell receptor peptides: epitope switching to a possible disease-protective determinant of myelin basic protein that is cross-reactive with a TCR BV peptide.
Immunology and cell biology 1998;76(1):83-90.
1998: Jack H Simon; Lawrence D Jacobs; MK Campion; Karl E Wende; Nancy Simonian; Diane L Cookfair; Richard A Rudick; Robert M Herndon; John R Richert; AM Salazar; J J Alam; Jill Fischer; Donald Goodkin; CV Granger; M Lajaunie; AL Martens-Davidson; M Meyer; Jeanelle Sheeder; K Choi; Ann L Scherzinger; DM Bartoszak; Dennis N Bourdette; J Braiman; Carol Brownscheidle; Ruth H Whitham
Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group.
Annals of neurology 1998;43(1):79-87.
1997: Richard A Rudick; Donald Goodkin; Lawrence D Jacobs; Diane L Cookfair; Robert M Herndon; John R Richert; AM Salazar; Jill Fischer; CV Granger; Jack H Simon; J J Alam; Nancy Simonian; MK Campion; DM Bartoszak; Dennis N Bourdette; J Braiman; Carol Brownscheidle; Michael E Coats; Stanley L Cohan; DS Dougherty; R Philip Kinkel; Michele K Mass; Frederick Munschauer; Roger Priore; Ruth H Whitham
Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG).
Neurology 1997;49(2):358-63.
1996: Yuan K Chou; A D Weinberg; Abigail C Buenafe; Dennis N Bourdette; Ruth H Whitham; J A Kaleeba; I Robey; D G Kavanagh; Halina Offner; Arthur Vandenbark
MHC-restriction, cytokine profile, and immunoregulatory effects of human T cells specific for TCR V beta CDR2 peptides: comparison with myelin basic protein-specific T cells.
Journal of neuroscience research 1996;45(6):838-51.
1996: Richard Jones; S Wesley; M Thompson; R Jacobs; Dennis N Bourdette
Phenotype and function of hematopoietic-derived cells in the CNS of SCID mouse-Lewis rat bone marrow chimeras.
Journal of neuroscience research 1996;45(6):723-34.
1996: Lawrence D Jacobs; Diane L Cookfair; Richard A Rudick; Robert M Herndon; John R Richert; AM Salazar; Jill Fischer; Donald Goodkin; C V Granger; Jack H Simon; J J Alam; DM Bartoszak; Dennis N Bourdette; J Braiman; Carol Brownscheidle; Michael E Coats; Stanley L Cohan; DS Dougherty; R Philip Kinkel; Michele K Mass; Frederick Munschauer; Roger Priore; PM Pullicino; B J Scherokman; Ruth H Whitham
Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)
Annals of neurology 1996;39(3):285-94.
1996: A D Weinberg; Dennis N Bourdette; T J Sullivan; M Lemon; J J Wallin; Richard T Maziarz; Michael P Davey; F Palida; W Godfrey; E Engleman; R J Fulton; Halina Offner; Arthur Vandenbark
Selective depletion of myelin-reactive T cells with the anti-OX-40 antibody ameliorates autoimmune encephalomyelitis.
Nature medicine 1996;2(2):183-9.
1995: Richard Jones; Ruth H Whitham; T Sullivan; Michele K Mass; Dennis N Bourdette
Encephalitogenic T lymphocytes develop from SJL/J hematopoietic cells transplanted into severe combined immunodeficient (SCID) mice.
Journal of neuroimmunology 1995;57(1-2):155-64.
1995: Richard Jones; Yuan K Chou; A Young; Michele K Mass; Arthur Vandenbark; Halina Offner; Dennis N Bourdette
T cells with encephalitogenic potential from multiple sclerosis patients and Lewis rats fail to induce disease in SCID mice following intracisternal injection.
Journal of neuroimmunology 1995;56(2):119-26.
1994: Richard Jones; A Weinberg; Dennis N Bourdette
Evidence for genetic contamination of inbred buffalo rats (RT-1b) obtained from a commercial vendor.
Journal of neuroimmunology 1994;52(2):215-8.
1994: A D Weinberg; J J Wallin; Richard Jones; T J Sullivan; Dennis N Bourdette; Arthur Vandenbark; Halina Offner
Target organ-specific up-regulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(9):4712-21.
1994: Yuan K Chou; W J Morrison; A D Weinberg; R Dedrick; Ruth H Whitham; Dennis N Bourdette; G Hashim; Halina Offner; Arthur Vandenbark
Immunity to TCR peptides in multiple sclerosis. II. T cell recognition of V beta 5.2 and V beta 6.1 CDR2 peptides.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2520-9.
1994: Dennis N Bourdette; Ruth H Whitham; Yuan K Chou; W J Morrison; J Atherton; C Kenny; D Liefeld; G A Hashim; Halina Offner; Arthur Vandenbark
Immunity to TCR peptides in multiple sclerosis. I. Successful immunization of patients with synthetic V beta 5.2 and V beta 6.1 CDR2 peptides.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2510-9.
1994: Yuan K Chou; Abigail C Buenafe; R Dedrick; W J Morrison; Dennis N Bourdette; Ruth H Whitham; J Atherton; J Lane; E Spoor; G A Hashim
T cell receptor V beta gene usage in the recognition of myelin basic protein by cerebrospinal fluid- and blood-derived T cells from patients with multiple sclerosis.
Journal of neuroscience research 1994;37(2):169-81.
1994: Yuan K Chou; Richard Jones; Dennis N Bourdette; Ruth H Whitham; G Hashim; J Atherton; Halina Offner; Arthur Vandenbark
Human myelin basic protein (MBP) epitopes recognized by mouse MBP-selected T cell lines from multiple sclerosis patients.
Journal of neuroimmunology 1994;49(1-2):45-50.
1993: Arthur Vandenbark; Dennis N Bourdette; Ruth H Whitham; Yuan K Chou; G A Hashim; Halina Offner
Episodic changes in T-cell frequencies to myelin basic protein in patients with multiple sclerosis.
Neurology 1993;43(11):2416-7.
1993: Richard Jones; Dennis N Bourdette; Ruth H Whitham; Halina Offner; Arthur Vandenbark
Induction of experimental autoimmune encephalomyelitis in severe combined immunodeficient mice reconstituted with allogeneic or xenogeneic hematopoietic cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(10):4620-9.
1993: K Satyanarayana; Yuan K Chou; Dennis N Bourdette; Ruth H Whitham; G A Hashim; Halina Offner; Arthur Vandenbark
Epitope specificity and V gene expression of cerebrospinal fluid T cells specific for intact versus cryptic epitopes of myelin basic protein.
Journal of neuroimmunology 1993;44(1):57-67.
1993: Arthur Vandenbark; Dennis N Bourdette; Ruth H Whitham; Yuan K Chou; G A Hashim; Halina Offner
T-cell receptor peptide therapy in EAE and MS.
Clinical and experimental rheumatology 1993;11 Suppl 8():S51-3.
1993: Dennis N Bourdette; A V Prochazka; W Mitchell; P Licari; J Burks
Health care costs of veterans with multiple sclerosis: implications for the rehabilitation of MS. VA Multiple Sclerosis Rehabilitation Study Group.
Archives of physical medicine and rehabilitation 1993;74(1):26-31.
1992: Yuan K Chou; Dennis N Bourdette; Halina Offner; Ruth H Whitham; R Y Wang; G A Hashim; Arthur Vandenbark
Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosis.
Journal of neuroimmunology 1992;38(1-2):105-13.
1992: Donald Goodkin; Diane L Cookfair; Karl E Wende; Dennis N Bourdette; P Pullicino; B Scherokman; Ruth H Whitham
Inter- and intrarater scoring agreement using grades 1.0 to 3.5 of the Kurtzke Expanded Disability Status Scale (EDSS). Multiple Sclerosis Collaborative Research Group.
Neurology 1992;42(4):859-63.
1992: Arthur Vandenbark; Yuan K Chou; Dennis N Bourdette; Ruth H Whitham; G A Hashim; Halina Offner
T cell receptor peptide therapy for autoimmune disease.
Journal of autoimmunity 1992;5 Suppl A():83-92.
1992: Richard Jones; Dennis N Bourdette; Halina Offner; Arthur Vandenbark
The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats.
Journal of neuroimmunology 1992;37(3):203-12.
1991: Dennis N Bourdette; M Vainiene; W Morrison; Richard Jones; M J Turner; G A Hashim; Arthur Vandenbark; Halina Offner
Myelin basic protein specific T cell lines and clones derived from the CNS of rats with EAE only recognize encephalitogenic epitopes.
Journal of neuroscience research 1991;30(2):308-15.
1991: Yuan K Chou; Paula Maria Henderikx; M Vainiene; Ruth H Whitham; Dennis N Bourdette; C H Chou; G Hashim; Halina Offner; Arthur Vandenbark
Specificity of human T cell clones reactive to immunodominant epitopes of myelin basic protein.
Journal of neuroscience research 1991;28(2):280-90.
1991: Ruth H Whitham; Dennis N Bourdette; G A Hashim; R M Herndon; R C Ilg; Arthur Vandenbark; Halina Offner
Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer relapsing demyelinating experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(1):101-7.
1990: Richard Jones; Dennis N Bourdette; Halina Offner; Arthur Vandenbark
Myelin basic protein-specific T cells induce demyelinating experimental autoimmune encephalomyelitis in Buffalo rats.
Journal of neuroimmunology 1990;30(1):61-9.
1990: Ruth H Whitham; Arthur Vandenbark; Dennis N Bourdette; Yuan K Chou; Halina Offner
Suppressor cell regulation of encephalitogenic T cell lines: generation of suppressor macrophages with cyclosporin A and myelin basic protein.
Cellular immunology 1990;126(2):290-303.
1990: Dennis N Bourdette; M J Turner; Arthur Vandenbark; Halina Offner
Characterization of basic protein-specific T cell lines selected from Lewis rats with relapsing experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 1990;26(1):81-5.
1989: Yuan K Chou; M Vainiene; Ruth H Whitham; Dennis N Bourdette; C H Chou; G Hashim; Halina Offner; Arthur Vandenbark
Response of human T lymphocyte lines to myelin basic protein: association of dominant epitopes with HLA class II restriction molecules.
Journal of neuroscience research 1989;23(2):207-16.
1989: Arthur Vandenbark; Yuan K Chou; Dennis N Bourdette; Ruth H Whitham; J Chilgren; C H Chou; G Konat; G Hashim; M Vainiene; Halina Offner
Human T lymphocyte response to myelin basic protein: selection of T lymphocyte lines from MBP-responsive donors.
Journal of neuroscience research 1989;23(1):21-30.
1989: Dennis N Bourdette; Arthur Vandenbark; G Hashim; Ruth H Whitham; Halina Offner
T cell lines selected with synthetic peptides are highly encephalitogenic in SJL/J mice.
Journal of neuroimmunology 1989;22(3):255-60.
1989: Dennis N Bourdette; B Zalc; N Baumann; F J Seil
Antisera to the ganglioside GM1 do not have anti-myelin or anti-axon activities in vitro.
Brain research 1989;478(1):175-80.
1988: Ruth H Whitham; G Nilaver; Dennis N Bourdette; F J Seil
Serum anti-myelin antibodies in chronic relapsing experimental allergic encephalomyelitis.
Journal of neuroimmunology 1988;18(2):155-70.
1988: Dennis N Bourdette; Arthur Vandenbark; C Meshul; Ruth H Whitham; Halina Offner
Basic protein-specific T-cell lines that induce experimental autoimmune encephalomyelitis in SJL/J mice: comparison with Lewis rat lines.
Cellular immunology 1988;112(2):351-63.
1988: Dennis N Bourdette; F J Seil; C K Meshul; J W Bigbee; G H DeVries; H C Agrawal
Antisera to an axolemma-enriched fraction have antiaxon and antimyelin effects in vitro.
Annals of the New York Academy of Sciences 1988;540():423-6.
1988: Ruth H Whitham; Dennis N Bourdette; Halina Offner; C K Meshul; Arthur Vandenbark
Suppressor cell regulation of chronic relapsing experimental allergic encephalomyelitis.
Annals of the New York Academy of Sciences 1988;540():537-9.
1987: Bruce M Coull; Dennis N Bourdette; S H Goodnight; D P Briley; Robert Hart
Multiple cerebral infarctions and dementia associated with anticardiolipin antibodies.
Stroke; a journal of cerebral circulation 1987;18(6):1107-12.
1986: Dennis N Bourdette; F J Seil; J W Bigbee; G H DeVries; M M Garwood; H C Agrawal
Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro.
Brain research 1986;366(1-2):333-7.
1986: Dennis N Bourdette; B F Driscoll; F J Seil; M W Kies; E C Alvord
Severity of demyelination in vivo correlates with serum myelination inhibition activity in guinea pigs having a new form of experimental allergic encephalomyelitis.
Neurochemical pathology 1986;4(1):1-9.
1984: Dennis N Bourdette; N L Rosenberg
Infiltrative orbitopathy, optic disk edema, and POEMS.
Neurology 1984;34(4):532-3.
1983: Dennis N Bourdette; N L Rosenberg; F M Yatsu
Herpes zoster ophthalmicus and delayed ipsilateral cerebral infarction.
Neurology 1983;33(11):1428-32.
1983: N L Rosenberg; Dennis N Bourdette
Hypertrophic neuropathy and multiple sclerosis.
Neurology 1983;33(10):1361-4.
1979: Dennis N Bourdette; B Greenberg
Twelve-year history of gastrointestinal bleeding in a patient with calcific aortic stenosis and hemorrhagic telangiectasia.
Digestive diseases and sciences 1979;24(1):77-9.