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J van Ark-Otte

Research Profile

Anatomy

Disorders

Chemicals & Drugs

Procedures

Drug Screening Assays, Antitumor

Physiology

Living Beings

Mouse

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Publications

TOP 3
A C Dingemans; J van Ark-Otte; Simone W Span; Giorgio V Scagliotti; Paul Van Der Valk; Pieter E Postmus; Giuseppe Giaccone
Topoisomerase IIalpha and other drug resistance markers in advanced non-small cell lung cancer.
AM Dingemans; J van Ark-Otte; Egbert F Smit; Pieter E Postmus; Giuseppe Giaccone
Validation of a polymerase chain reaction aided transcript titration assay (PATTY) for topoisomerase II in lung cancer samples.
Epie Boven; HERBERT PINEDO; Annemarie H Van Hattum; Peter G Scheffer; W H Peters; C A M Erkelens; Hennie M M Schlüper; CM Kuiper; J van Ark-Otte; Giuseppe Giaccone
Characterization of human soft-tissue sarcoma xenografts for use in secondary drug screening.

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All Publications

2001: A C Dingemans; J van Ark-Otte; Simone W Span; Giorgio V Scagliotti; Paul Van Der Valk; Pieter E Postmus; Giuseppe Giaccone
Topoisomerase IIalpha and other drug resistance markers in advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2001;32(2):117-28.
2000: AM Dingemans; J van Ark-Otte; Egbert F Smit; Pieter E Postmus; Giuseppe Giaccone
Validation of a polymerase chain reaction aided transcript titration assay (PATTY) for topoisomerase II in lung cancer samples.
Anticancer research 2000;20(5B):3549-54.
1998: Epie Boven; HERBERT PINEDO; Annemarie H Van Hattum; Peter G Scheffer; W H Peters; C A M Erkelens; Hennie M M Schlüper; CM Kuiper; J van Ark-Otte; Giuseppe Giaccone
Characterization of human soft-tissue sarcoma xenografts for use in secondary drug screening.
British journal of cancer 1998;78(12):1586-93.
1998: J van Ark-Otte; Marc A Kedde; Wim J F van der Vijgh; AM Dingemans; WJ Jansen; HERBERT PINEDO; Epie Boven; Giuseppe Giaccone
Determinants of CPT-11 and SN-38 activities in human lung cancer cells.
British journal of cancer 1998;77(12):2171-6.
1998: WJ Jansen; Theresia M Hulscher; J van Ark-Otte; Giuseppe Giaccone; HERBERT PINEDO; Epie Boven
CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein.
British journal of cancer 1998;77(3):359-65.
1998: J van Ark-Otte; G Samelis; G Rubio; J B Lopez Saez; HERBERT PINEDO; Giuseppe Giaccone
Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes.
Oncology reports 1998;5(1):249-55.
1997: WJ Jansen; Geertruida M Kolfschoten; C A M Erkelens; J van Ark-Otte; HERBERT PINEDO; Epie Boven
Anti-tumor activity of CPT-11 in experimental human ovarian cancer and human soft-tissue sarcoma.
International journal of cancer. Journal international du cancer 1997;73(6):891-6.
1997: R M Apolinario; Paul Van Der Valk; JS De Jong; W Deville; J van Ark-Otte; AM Dingemans; Johan C van Mourik; Pieter E Postmus; HERBERT PINEDO; Giuseppe Giaccone
Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(6):2456-66.
1996: AM Dingemans; J van Ark-Otte; Paul Van Der Valk; R M Apolinario; Rik J Scheper; Pieter E Postmus; Giuseppe Giaccone
Expression of the human major vault protein LRP in human lung cancer samples and normal lung tissues.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(6):625-30.
1996: Giuseppe Giaccone; J van Ark-Otte; G J Rubio; A F Gazdar; Henk J Broxterman; AM Dingemans; Marcel J Flens; Rik J Scheper; HERBERT PINEDO
MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lungs.
International journal of cancer. Journal international du cancer 1996;66(6):760-7.
1995: Giuseppe Giaccone; J van Ark-Otte; Giorgio V Scagliotti; G Capranico; Paul Van Der Valk; G Rubio; O Dalesio; R Lopez; F Zunino; J Walboomers
Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung.
Biochimica et biophysica acta 1995;1264(3):337-46.
1995: Miguel A Izquierdo; Paul Van Der Valk; J van Ark-Otte; G Rubio; J R Germa-Lluch; R Ueda; Rik J Scheper; T Takahashi; Giuseppe Giaccone
Differential expression of the c-kit proto-oncogene in germ cell tumours.
The Journal of pathology 1995;177(3):253-8.
1995: G J Rubio; HERBERT PINEDO; J Virizuela; J van Ark-Otte; Giuseppe Giaccone
Effects of suramin on human lung cancer cell lines.
European journal of cancer (Oxford, England : 1990) 1995;31A(2):244-51.
1994: P E Pizao; E Smitskamp-Wilms; J van Ark-Otte; Jos H Beijnen; Godefridus J Peters; HERBERT PINEDO; Giuseppe Giaccone
Antiproliferative activity of the topoisomerase I inhibitors topotecan and camptothecin, on sub- and postconfluent tumor cell cultures.
Biochemical pharmacology 1994;48(6):1145-54.
1994: E Smitskamp-Wilms; Godefridus J Peters; HERBERT PINEDO; J van Ark-Otte; Giuseppe Giaccone
Chemosensitivity to the indoloquinone EO9 is correlated with DT-diaphorase activity and its gene expression.
Biochemical pharmacology 1994;47(8):1325-32.
1994: R Lopez; Godefridus J Peters; E Smitskamp-Wilms; J A Virizuela; J van Ark-Otte; HERBERT PINEDO; Giuseppe Giaccone
In vitro sequence-dependent synergistic effect of suramin and camptothecin.
European journal of cancer (Oxford, England : 1990) 1994;30A(11):1670-4.
1993: Godefridus J Peters; M Wets; Y P Keepers; R Oskam; J van Ark-Otte; Paul Noordhuis; Kees Smid; HERBERT PINEDO
Transformation of mouse fibroblasts with the oncogenes H-ras OR trk is associated with pronounced changes in drug sensitivity and metabolism.
International journal of cancer. Journal international du cancer 1993;54(3):450-5.
1993: P E Pizao; Godefridus J Peters; J van Ark-Otte; L A Smets; E Smitskamp-Wilms; B Winograd; HERBERT PINEDO; Giuseppe Giaccone
Cytotoxic effects of anticancer agents on subconfluent and multilayered postconfluent cultures.
European journal of cancer (Oxford, England : 1990) 1993;29A(11):1566-73.
1992: P E Pizao; D M Lyaruu; Godefridus J Peters; J van Ark-Otte; B Winograd; Giuseppe Giaccone; HERBERT PINEDO
Growth, morphology and chemosensitivity studies on postconfluent cells cultured in 'V'-bottomed microtiter plates.
British journal of cancer 1992;66(4):660-5.
1991: Y P Keepers; P E Pizao; Godefridus J Peters; J van Ark-Otte; B Winograd; HERBERT PINEDO
Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing.
European journal of cancer (Oxford, England : 1990) 1991;27(7):897-900.