Theo van Berkel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Living Beings

Chemicals & Drugs

Disorders

Atherosclerosis

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
de Jager Saskia C A; Canté-Barrett Kirsten; Bot Ilze; Husberg Cathrine; van Puijvelde Gijs H; van Santbrink Peter J; Yndestad Arne; van den Oever Jessica M E; Kuiper Johan; van Berkel Theo J C; Lipp Martin; Zwaginga Jaap Jan; Fibbe Wim E; Aukrust Pål; Biessen Erik A L
Impaired effector memory T-cell regulation facilitates graft versus host disease in CCR7-deficient bone marrow transplant chimeras.
van Puijvelde Gijs H M; van Wanrooij Eva J A; Hauer Arnaud D; de Vos Paula; van Berkel Theo J C; Kuiper Johan
Effect of natural killer T cell activation on the initiation of atherosclerosis.
Lammers Bart; Out Ruud; Hildebrand Reeni B; Quinn Carmel M; Williamson David; Hoekstra Menno; Meurs Illiana; Van Berkel Theo J C; Jessup Wendy; Van Eck Miranda
Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Theo van Berkel (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: de Jager Saskia C A; Canté-Barrett Kirsten; Bot Ilze; Husberg Cathrine; van Puijvelde Gijs H; van Santbrink Peter J; Yndestad Arne; van den Oever Jessica M E; Kuiper Johan; van Berkel Theo J C; Lipp Martin; Zwaginga Jaap Jan; Fibbe Wim E; Aukrust Pål; Biessen Erik A L
Impaired effector memory T-cell regulation facilitates graft versus host disease in CCR7-deficient bone marrow transplant chimeras.
Transplantation 2009;88(5):631-9.
2009: van Puijvelde Gijs H M; van Wanrooij Eva J A; Hauer Arnaud D; de Vos Paula; van Berkel Theo J C; Kuiper Johan
Effect of natural killer T cell activation on the initiation of atherosclerosis.
Thrombosis and haemostasis 2009;102(2):223-30.
2009: Lammers Bart; Out Ruud; Hildebrand Reeni B; Quinn Carmel M; Williamson David; Hoekstra Menno; Meurs Illiana; Van Berkel Theo J C; Jessup Wendy; Van Eck Miranda
Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development.
Atherosclerosis 2009;205(2):420-6.
2009: Eefting Daniël; Bot Ilze; de Vries Margreet R; Schepers Abbey; van Bockel J Hajo; Van Berkel Theo J C; Biessen Erik A L; Quax Paul H A
Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2009;50(1):152-60.
2009: Hoekstra Menno; Ye Dan; Hildebrand Reeni B; Zhao Ying; Lammers Bart; Stitzinger Miranda; Kuiper Johan; Van Berkel Theo J C; Van Eck Miranda
Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production.
Journal of lipid research 2009;50(6):1039-46.
2009: Hauer Arnaud D; Habets Kim L L; van Wanrooij Eva J A; de Vos Paula; Krueger Joerg; Reisfeld Ralph A; van Berkel Theo J C; Kuiper Johan
Vaccination against TIE2 reduces atherosclerosis.
Atherosclerosis 2009;204(2):365-71.
2009: MacDonald Marcia L E; van Eck Miranda; Hildebrand Reeni B; Wong Brian W C; Bissada Nagat; Ruddle Piers; Kontush Anatol; Hussein Hala; Pouladi Mahmoud A; Chapman M John; Fievet Catherine; van Berkel Theo J C; Staels Bart; McManus Bruce M; Hayden Michael R
Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(3):341-7.
2009: Guo Jian; Bot Ilze; de Nooijer Ramon; Hoffman Sandra J; Stroup George B; Biessen Erik A L; Benson G Martin; Groot Pieter H E; Van Eck Miranda; Van Berkel Theo J C
Leucocyte cathepsin K affects atherosclerotic lesion composition and bone mineral density in low-density lipoprotein receptor deficient mice.
Cardiovascular research 2009;81(2):278-85.
2009: Hoekstra Menno; Lammers Bart; Out Ruud; Li Zhaosha; Van Eck Miranda; Van Berkel Theo J C
Activation of the nuclear receptor PXR decreases plasma LDL-cholesterol levels and induces hepatic steatosis in LDL receptor knockout mice.
Molecular pharmaceutics 2009;6(1):182-9.
2008: de Haan Willeke; Out Ruud; Berbée Jimmy F P; van der Hoogt Caroline C; van Dijk Ko Willems; van Berkel Theo J C; Romijn Johannes A; Jukema J Wouter; Havekes Louis M; Rensen Patrick C N
Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.
Biochemical and biophysical research communications 2008;377(4):1294-8.
2008: de Jager Saskia C A; Kraaijeveld Adriaan O; Grauss Robert W; de Jager Wilco; Liem Su-San; van der Hoeven Bas L; Prakken Berent J; Putter Hein; van Berkel Theo J C; Atsma Douwe E; Schalij Martin J; Jukema J Wouter; Biessen Erik A L
CCL3 (MIP-1 alpha) levels are elevated during acute coronary syndromes and show strong prognostic power for future ischemic events.
Journal of molecular and cellular cardiology 2008;45(3):446-52.
2008: Hu Lihui; van der Hoogt Caroline C; Espirito Santo Sonia M S; Out Ruud; Kypreos Kyriakos E; van Vlijmen Bart J M; Van Berkel Theo J C; Romijn Johannes A; Havekes Louis M; van Dijk Ko Willems; Rensen Patrick C N
The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.
Journal of lipid research 2008;49(7):1553-61.
2008: van Wanrooij Eva J A; de Vos Paula; Bixel M Gabriele; Vestweber Dietmar; van Berkel Theo J C; Kuiper Johan
Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein receptor-deficient mice.
Cardiovascular research 2008;78(3):590-6.
2008: Hoekstra Menno; Meurs Illiana; Koenders Mieke; Out Ruud; Hildebrand Reeni B; Kruijt J Kar; Van Eck Miranda; Van Berkel Theo J C
Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting.
Journal of lipid research 2008;49(4):738-45.
2008: van Wanrooij Eva J A; de Jager Saskia C A; van Es Thomas; de Vos Paula; Birch Helen L; Owen David A; Watson Robbert J; Biessen Erik A L; Chapman Gayle A; van Berkel Theo J C; Kuiper Johan
CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(2):251-7.
2008: Out Ruud; Hoekstra Menno; Habets Kim; Meurs Illiana; de Waard Vivian; Hildebrand Reeni B; Wang Yanan; Chimini Giovanna; Kuiper Johan; Van Berkel Theo J C; Van Eck Miranda
Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(2):258-64.
2008: Ye Dan; Hoekstra Menno; Out Ruud; Meurs Illiana; Kruijt J Kar; Hildebrand Reeni B; Van Berkel Theo J C; Van Eck Miranda
Hepatic cell-specific ATP-binding cassette (ABC) transporter profiling identifies putative novel candidates for lipid homeostasis in mice.
Atherosclerosis 2008;196(2):650-8.
2008: Out Ruud; Jessup Wendy; Le Goff Wilfried; Hoekstra Menno; Gelissen Ingrid C; Zhao Ying; Kritharides Leonard; Chimini Giovanna; Kuiper Johan; Chapman M John; Huby Thierry; Van Berkel Theo J C; Van Eck Miranda
Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1.
Circulation research 2008;102(1):113-20.
2008: Van Eck Miranda; Hoekstra Menno; Out Ruud; Bos I Sophie T; Kruijt J Kar; Hildebrand Reeni B; Van Berkel Theo J C
Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo.
Journal of lipid research 2008;49(1):136-46.
2007: Hawinkels Lukas J A C; van Rossenberg Sabine M W; de Jonge-Muller Eveline S M; Molenaar Tom J M; Appeldoorn Chantal C M; van Berkel Theo J C; Sier Cornelis F M; Biessen Erik A L
Efficient degradation-aided selection of protease inhibitors by phage display.
Biochemical and biophysical research communications 2007;364(3):549-55.
2007: van Puijvelde G H M; van Es T; van Wanrooij E J A; Habets K L L; de Vos P; van der Zee R; van Eden W; van Berkel Th J C; Kuiper J
Induction of oral tolerance to HSP60 or an HSP60-peptide activates T cell regulation and reduces atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2677-83.
2007: Korporaal Suzanne J A; Van Eck Miranda; Adelmeijer Jelle; Ijsseldijk Martin; Out Ruud; Lisman Ton; Lenting Peter J; Van Berkel Theo J C; Akkerman Jan-Willem N
Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(11):2476-83.
2007: Van Eck Miranda; Hoekstra Menno; Hildebrand Reeni B; Yaong Yuemang; Stengel Dominique; Kruijt J Kar; Sattler Wolfgang; Tietge Uwe J F; Ninio Ewa; Van Berkel Theo J C; Praticò Domenico
Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(11):2413-9.
2007: Westerterp Marit; Van Eck Miranda; de Haan Willeke; Offerman Erik H; Van Berkel Theo J C; Havekes Louis M; Rensen Patrick C N
Apolipoprotein CI aggravates atherosclerosis development in ApoE-knockout mice despite mediating cholesterol efflux from macrophages.
Atherosclerosis 2007;195(1):e9-16.
2007: Kraaijeveld A O; de Jager S C A; de Jager W J; Prakken B J; McColl S R; Haspels I; Putter H; van Berkel T J C; Nagelkerken L; Jukema J W; Biessen E A L
CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms.
Circulation 2007;116(17):1931-41.
2007: Pennings Marieke; Hildebrand Reeni B; Ye Dan; Kunne Cindy; Van Berkel Theo J C; Groen Albert K; Van Eck Miranda
Bone marrow-derived multidrug resistance protein ABCB4 protects against atherosclerotic lesion development in LDL receptor knockout mice.
Cardiovascular research 2007;76(1):175-83.
2007: Bot Ilze; van Berkel Theo Jc; Biessen Erik Al
Viral serine protease inhibitors as anti-atherosclerotic therapy.
Current opinion in investigational drugs (London, England : 2000) 2007;8(9):729-35.
2007: Hauer Arnaud D; van Puijvelde Gijs H M; Peterse Niels; de Vos Paula; van Weel Vincent; van Wanrooij Eva J A; Biessen Erik A L; Quax Paul H A; Niethammer Andreas G; Reisfeld Ralph A; van Berkel Theo J C; Kuiper Johan
Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(9):2050-7.
2007: Volger Oscar L; Fledderus Joost O; Kisters Natasja; Fontijn Ruud D; Moerland Perry D; Kuiper Johan; van Berkel Theo J; Bijnens Ann-Pascale J J; Daemen Mat J A P; Pannekoek Hans; Horrevoets Anton J G
Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis.
The American journal of pathology 2007;171(1):326-37.
2007: Herczenik Eszter; Bouma Barend; Korporaal Suzanne J A; Strangi Remo; Zeng Qinghong; Gros Piet; Van Eck Miranda; Van Berkel Theo J C; Gebbink Martijn F B G; Akkerman Jan-Willem N
Activation of human platelets by misfolded proteins.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(7):1657-65.
2007: Yan Daoguang; Jauhiainen Matti; Hildebrand Reeni B; Willems van Dijk Ko; Van Berkel Theo J C; Ehnholm Christian; Van Eck Miranda; Olkkonen Vesa M
Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(7):1618-24.
2007: Triesscheijn Martijn; Ruevekamp Marjan; Out Ruud; Van Berkel Theo J C; Schellens Jan; Baas Paul; Stewart Fiona A
The pharmacokinetic behavior of the photosensitizer meso-tetra-hydroxyphenyl-chlorin in mice and men.
Cancer chemotherapy and pharmacology 2007;60(1):113-22.
2007: Bot Ilze; de Jager Saskia C A; Zernecke Alma; Lindstedt Ken A; van Berkel Theo J C; Weber Christian; Biessen Erik A L
Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice.
Circulation 2007;115(19):2516-25.
2007: Fledderus Joost O; van Thienen Johannes V; Boon Reinier A; Dekker Rob J; Rohlena Jakub; Volger Oscar L; Bijnens Ann-Pascale J J; Daemen Mat J A P; Kuiper Johan; van Berkel Theo J C; Pannekoek Hans; Horrevoets Anton J G
Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2.
Blood 2007;109(10):4249-57.
2007: Van Eck Miranda; Ye Dan; Hildebrand Reeni B; Kar Kruijt J; de Haan Willeke; Hoekstra Menno; Rensen Patrick C N; Ehnholm Christian; Jauhiainen Matti; Van Berkel Theo J C
Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice.
Circulation research 2007;100(5):678-85.
2007: Out Ruud; Hoekstra Menno; Meurs Illiana; de Vos Paula; Kuiper Johan; Van Eck Miranda; Van Berkel Theo J C
Total body ABCG1 expression protects against early atherosclerotic lesion development in mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):594-9.
2007: Vikstedt Riikka; Ye Dan; Metso Jari; Hildebrand Reeni B; Van Berkel Theo J C; Ehnholm Christian; Jauhiainen Matti; Van Eck Miranda
Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):578-86.
2007: van Wanrooij Eva J A; van Puijvelde Gijs H M; de Vos Paula; Yagita Hideo; van Berkel Theo J C; Kuiper Johan
Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):204-10.
2007: Lucerna Markus; Zernecke Alma; de Nooijer Ramon; de Jager Saskia C; Bot Ilze; van der Lans Christian; Kholova Ivana; Liehn Elisa A; van Berkel Theo J C; Yla-Herttuala Seppo; Weber Christian; Biessen Eric A L
Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment.
Blood 2007;109(1):122-9.
2007: Yu Haixiang; van Berkel Theo J C; Biessen Erik A L
Therapeutic potential of VIVIT, a selective peptide inhibitor of nuclear factor of activated T cells, in cardiovascular disorders.
Cardiovascular drug reviews 2007;25(2):175-87.
2007: Kraaijeveld A O; de Jager S C A; van Berkel T J C; Biessen E A L; Jukema J W
Chemokines and atherosclerotic plaque progression: towards therapeutic targeting?
Current pharmaceutical design 2007;13(10):1039-52.
2006: Kruit Janine-K; Groen Albert K; van Berkel Theo J; Kuipers Folkert
Emerging roles of the intestine in control of cholesterol metabolism.
World journal of gastroenterology : WJG 2006;12(40):6429-39.
2006: van Puijvelde G H M; Hauer A D; de Vos P; van den Heuvel R; van Herwijnen M J C; van der Zee R; van Eden W; van Berkel T J C; Kuiper J
Induction of oral tolerance to oxidized low-density lipoprotein ameliorates atherosclerosis.
Circulation 2006;114(18):1968-76.
2006: Pennings Marieke; Meurs Illiana; Ye Dan; Out Ruud; Hoekstra Menno; Van Berkel Theo J C; Van Eck Miranda
Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development.
FEBS letters 2006;580(23):5588-96.
2006: Hoekstra Menno; Stitzinger Miranda; van Wanrooij Eva J A; Michon Ingrid N; Kruijt J Kar; Kamphorst J; Van Eck M; Vreugdenhil E; Van Berkel Theo J C; Kuiper Johan
Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet.
Journal of lipid research 2006;47(10):2198-207.
2006: Out Ruud; Hoekstra Menno; Hildebrand Reeni B; Kruit Janine K; Meurs Illiana; Li Zhaosha; Kuipers Folkert; Van Berkel Theo J C; Van Eck Miranda
Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2295-300.
2006: Singaraja Roshni R; Van Eck Miranda; Bissada Nagat; Zimetti Francesca; Collins Heidi L; Hildebrand Reeni B; Hayden Anna; Brunham Liam R; Kang Martin H; Fruchart Jean-Charles; Van Berkel Theo J C; Parks John S; Staels Bart; Rothblat George H; Fiévet Catherine; Hayden Michael R
Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Circulation 2006;114(12):1301-9.
2006: Yu Haixiang; Sliedregt-Bol Karen; Overkleeft Herman; van der Marel Gijs A; van Berkel Theo J C; Biessen Erik A L
Therapeutic potential of a synthetic peptide inhibitor of nuclear factor of activated T cells as antirestenotic agent.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(7):1531-7.
2006: Rensen Patrick C N; Gras J C Emile; Lindfors Eva K; van Dijk Ko Willems; Jukema J Wouter; van Berkel Theo J C; Biessen Erik A L
Selective targeting of liposomes to macrophages using a ligand with high affinity for the macrophage scavenger receptor class A.
Current drug discovery technologies 2006;3(2):135-44.
2006: Emile Gras J C; Verkuijlen Paul; Frants Rune R; Havekes Louis M; van Berkel Theo J C; Biessen Erik A L; van Dijk K Willems
Specific and efficient targeting of adenovirus vectors to macrophages: application of a fusion protein between an adenovirus-binding fragment and avidin, linked to a biotinylated oligonucleotide.
The journal of gene medicine 2006;8(6):668-78.
2006: Van Eck Miranda; Singaraja Roshni R; Ye Dan; Hildebrand Reeni B; James Erick R; Hayden Michael R; Van Berkel Theo J C
Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):929-34.
2006: de Nooijer R; Verkleij C J N; von der Thüsen J H; Jukema J W; van der Wall E E; van Berkel Thüsen J C; Baker A H; Biessen E A L
Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(2):340-6.
2006: Rensen Patrick C N; Sliedregt Leo A J M; van Santbrink Peter J; Ferns Michiel; Schifferstein Hendrik N J; van Leeuwen Steven H; Souverijn John H M; van Berkel Theo J C; Biessen Erik A L
Stimulation of liver-directed cholesterol flux in mice by novel N-acetylgalactosamine-terminated glycolipids with high affinity for the asialoglycoprotein receptor.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):169-75.
2006: Hauer A D; de Vos P; Peterse N; ten Cate H; van Berkel Th J C; Stassen F R M; Kuiper J
Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr-/- mice.
Cardiovascular research 2006;69(1):280-8.
2005: Krom Y D; Gras J C E; Frants R R; Havekes L M; van Berkel T J; Biessen E A L; van Dijk K Willems
Efficient targeting of adenoviral vectors to integrin positive vascular cells utilizing a CAR-cyclic RGD linker protein.
Biochemical and biophysical research communications 2005;338(2):847-54.
2005: van Wanrooij Eva J A; Happé Hester; Hauer Arnaud D; de Vos Paula; Imanishi Takeshi; Fujiwara Hiromi; van Berkel Theo J C; Kuiper Johan
HIV entry inhibitor TAK-779 attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2642-7.
2005: Eck Miranda Van; Oost Jenina; Goudriaan Jeltje R; Hoekstra Menno; Hildebrand Reeni B; Bos I Sophie T; van Dijk Ko Willems; Van Berkel Theo J C
Role of the macrophage very-low-density lipoprotein receptor in atherosclerotic lesion development.
Atherosclerosis 2005;183(2):230-7.
2005: Zadelaar A Susanne M; von der Thüsen Jan H; Boesten Lianne S M; Hoeben Rob C; Kockx Mark M; Versnel Marjan A; van Berkel Theo J C; Havekes Louis M; Biessen Erik A L; van Vlijmen Bart J M
Increased vulnerability of pre-existing atherosclerosis in ApoE-deficient mice following adenovirus-mediated Fas ligand gene transfer.
Atherosclerosis 2005;183(2):244-50.
2005: Meurs Illiana; Hoekstra Menno; van Wanrooij Eva J A; Hildebrand Reeni B; Kuiper Johan; Kuipers Folkert; Hardeman Max R; Van Berkel Theo J C; Van Eck Miranda
HDL cholesterol levels are an important factor for determining the lifespan of erythrocytes.
Experimental hematology 2005;33(11):1309-19.
2005: van Berkel Theo J C; Out Ruud; Hoekstra Menno; Kuiper Johan; Biessen Erik; van Eck Miranda
Scavenger receptors: friend or foe in atherosclerosis?
Current opinion in lipidology 2005;16(5):525-35.
2005: Hauer A D; Uyttenhove C; de Vos P; Stroobant V; Renauld J C; van Berkel T J C; van Snick J; Kuiper J
Blockade of interleukin-12 function by protein vaccination attenuates atherosclerosis.
Circulation 2005;112(7):1054-62.
2005: Dekker Rob J; van Thienen Johannes V; Rohlena Jakub; de Jager Saskia C; Elderkamp Yvonne W; Seppen Jurgen; de Vries Carlie J M; Biessen Erik A L; van Berkel Theo J C; Pannekoek Hans; Horrevoets Anton J G
Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes.
The American journal of pathology 2005;167(2):609-18.
2005: Tietge Uwe J F; Pratico Domenico; Ding Tao; Funk Colin D; Hildebrand Reeni B; Van Berkel Theo; Van Eck Miranda
Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress.
Journal of lipid research 2005;46(8):1604-14.
2005: Bot Ilze; Guo Jian; Van Eck Miranda; Van Santbrink Peter J; Groot Pieter H E; Hildebrand Reeni B; Seppen Jurgen; Van Berkel Theo J C; Biessen Erik A L
Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo.
Blood 2005;106(4):1147-53.
2005: Guo Jian; Van Eck Miranda; de Waard Vivian; Maeda Nobuyo; Benson G Martin; Groot Pieter H E; Van Berkel Theo J C
The presence of leukocyte CC-chemokine receptor 2 in CCR2 knockout mice promotes atherogenesis.
Biochimica et biophysica acta 2005;1740(3):453-9.
2005: Van Eck Miranda; Pennings Marieke; Hoekstra Menno; Out Ruud; Van Berkel Theo Jc
Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis.
Current opinion in lipidology 2005;16(3):307-15.
2005: Donners Marjo M P C; Bot Ilze; De Windt Leon J; van Berkel Theo J C; Daemen Mat J A P; Biessen Erik A L; Heeneman Sylvia
Low-dose FK506 blocks collar-induced atherosclerotic plaque development and stabilizes plaques in ApoE-/- mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(6):1204-15.
2005: Out Ruud; Hoekstra Menno; de Jager Saskia C A; de Vos Paula; van der Westhuyzen Deneys R; Webb Nancy R; Van Eck Miranda; Biessen Eric A L; Van Berkel Theo J C
Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice.
Journal of lipid research 2005;46(6):1172-81.
2005: Guo Jian; de Waard Vivian; Van Eck Miranda; Hildebrand Reeni B; van Wanrooij Eva J A; Kuiper Johan; Maeda Nobuyo; Benson G Martin; Groot Pieter H E; Van Berkel Theo J C
Repopulation of apolipoprotein E knockout mice with CCR2-deficient bone marrow progenitor cells does not inhibit ongoing atherosclerotic lesion development.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(5):1014-9.
2005: Hoekstra Menno; Out Ruud; Kruijt Johan Kar; Van Eck Miranda; Van Berkel Theo J C
Diet induced regulation of genes involved in cholesterol metabolism in rat liver parenchymal and Kupffer cells.
Journal of hepatology 2005;42(3):400-7.
2005: Willekens Frans L A; Werre Jan M; Kruijt J Kar; Roerdinkholder-Stoelwinder Bregt; Groenen-Döpp Yvonne A M; van den Bos Annegeet G; Bosman Giel J C G M; van Berkel Theo J C
Liver Kupffer cells rapidly remove red blood cell-derived vesicles from the circulation by scavenger receptors.
Blood 2005;105(5):2141-5.
2005: Appeldoorn Chantal C M; Bonnefoy Arnaud; Lutters Bianca C H; Daenens Kim; van Berkel Theo J C; Hoylaerts Marc F; Biessen Erik A L
Gallic acid antagonizes P-selectin-mediated platelet-leukocyte interactions: implications for the French paradox.
Circulation 2005;111(1):106-12.
2004: Korporaal Suzanne J A; Relou Ingrid A M; van Eck Miranda; Strasser Vera; Bezemer Martineke; Gorter Gertie; van Berkel Theo J C; Nimpf Johannes; Akkerman Jan-Willem N; Lenting Peter J
Binding of low density lipoprotein to platelet apolipoprotein E receptor 2' results in phosphorylation of p38MAPK.
The Journal of biological chemistry 2004;279(50):52526-34.
2004: Rensen Patrick C N; van Leeuwen Steven H; Sliedregt Leo A J M; van Berkel Theo J C; Biessen Erik A L
Design and synthesis of novel N-acetylgalactosamine-terminated glycolipids for targeting of lipoproteins to the hepatic asialoglycoprotein receptor.
Journal of medicinal chemistry 2004;47(23):5798-808.
2004: Out Ruud; Hoekstra Menno; Spijkers John A A; Kruijt Johan K; van Eck Miranda; Bos Ingrid S T; Twisk Jaap; Van Berkel Theo J C
Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice.
Journal of lipid research 2004;45(11):2088-95.
2004: Lutters Bianca C H; Leeuwenburgh Michiel A; Appeldoorn Chantal C M; Molenaar Tom J M; Van Berkel Theo J C; Biessen Erik A L
Blocking endothelial adhesion molecules: a potential therapeutic strategy to combat atherogenesis.
Current opinion in lipidology 2004;15(5):545-52.
2004: Van Eck Miranda; Bos I Sophie T; Hildebrand Reeni B; Van Rij Brechje T; Van Berkel Theo J C
Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development.
The American journal of pathology 2004;165(3):785-94.
2004: Out Ruud; Kruijt J Kar; Rensen Patrick C N; Hildebrand Reeni B; de Vos Paula; Van Eck Miranda; Van Berkel Theo J C
Scavenger receptor BI plays a role in facilitating chylomicron metabolism.
The Journal of biological chemistry 2004;279(18):18401-6.
2004: van Rossenberg S M W; van Keulen A C I; Drijfhout J-W; Vasto S; Koerten H K; Spies F; van 't Noordende J M; van Berkel Th J C; Biessen E A L
Stable polyplexes based on arginine-containing oligopeptides for in vivo gene delivery.
Gene therapy 2004;11(5):457-64.
2004: von der Thüsen Jan H; Fekkes Madelon L; Passier Robert; van Zonneveld A J; Mainfroid V; van Berkel Theo J C; Biessen Erik A L
Adenoviral transfer of endothelial nitric oxide synthase attenuates lesion formation in a novel murine model of postangioplasty restenosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(2):357-62.
2003: van Rossenberg Sabine M W; Sliedregt-Bol Karen M; Prince Perry; van Berkel Theo J C; van Boom Jacques H; van der Marel Gijs A; Biessen Erik A L
A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes.
Bioconjugate chemistry 2003;14(6):1077-82.
2003: Molenaar Tom J M; Twisk Jaap; de Haas Sonja A M; Peterse Niels; Vogelaar Bram J C P; van Leeuwen Steven H; Michon Ingrid N; van Berkel Theo J C; Kuiper Johan; Biessen Erik A L
P-selectin as a candidate target in atherosclerosis.
Biochemical pharmacology 2003;66(5):859-66.
2003: Bot Ilze; von der Thüsen Jan H; Donners Marjo M P C; Lucas Alexandra; Fekkes Madelon L; de Jager Saskia C A; Kuiper Johan; Daemen Mat J A P; van Berkel Theo J C; Heeneman Sylvia; Biessen Erik A L
Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice.
Circulation research 2003;93(5):464-71.
2003: Florea B I; Molenaar T J M; Bot I; Michon I N; Kuiper J; Van Berkel T J C; Junginger H E; Biessen E A L; Borchard G
Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways.
Journal of drug targeting 2003;11(7):383-90.
2003: 't Hoen Peter A C; Van der Lans Christian A C; Van Eck Miranda; Bijsterbosch Martin K; Van Berkel Theo J C; Twisk Jaap
Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes.
Circulation research 2003;93(3):262-9.
2003: Van Amersfoort Edwin S; Van Berkel Theo J C; Kuiper Johan
Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock.
Clinical microbiology reviews 2003;16(3):379-414.
2003: van Rossenberg Sabine M W; Sliedregt-Bol Karen M; Koning Gerben; van den Elst Hans; van Berkel Theo J C; van Boom Jacques H; van der Marel Gijs A; Biessen Erik A L
Improvement of hepatocyte-specific gene expression by a targeted colchicine prodrug.
Chembiochem : a European journal of chemical biology 2003;4(7):633-9.
2003: Hoekstra Menno; Kruijt J Kar; Van Eck Miranda; Van Berkel Theo J C
Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells.
The Journal of biological chemistry 2003;278(28):25448-53.
2003: Van Eck Miranda; Twisk Jaap; Hoekstra Menno; Van Rij Brechje T; Van der Lans Christian A C; Bos I Sophie T; Kruijt J Kar; Kuipers Folkert; Van Berkel Theo J C
Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver.
The Journal of biological chemistry 2003;278(26):23699-705.
2003: von der Thüsen Jan H; Kuiper Johan; van Berkel Theo J C; Biessen Erik A L
Interleukins in atherosclerosis: molecular pathways and therapeutic potential.
Pharmacological reviews 2003;55(1):133-66.
2003: Guo Jian; Van Eck Miranda; Twisk Jaap; Maeda Nobuyo; Benson G Martin; Groot Pieter H E; Van Berkel Theo J C
Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(3):447-53.
2003: Appeldoorn Chantal C M; Molenaar Tom J M; Bonnefoy Arnaud; van Leeuwen Steven H; Vandervoort Petra A H; Hoylaerts Marc F; van Berkel Theo J C; Biessen Erik A L
Rational optimization of a short human P-selectin-binding peptide leads to nanomolar affinity antagonists.
The Journal of biological chemistry 2003;278(12):10201-7.
2002: 't Hoen Peter A C; Out Ruud; Commandeur Jan N M; Vermeulen Nico P E; van Batenburg F H D; Manoharan Muthiah; van Berkel Theo J C; Biessen Erik A L; Bijsterbosch Martin K
Selection of antisense oligodeoxynucleotides against glutathione S-transferase Mu.
RNA (New York, N.Y.) 2002;8(12):1572-83.
2002: Molenaar Tom J M; Appeldoorn Chantal C M; de Haas Sonja A M; Michon Ingrid N; Bonnefoy Arnaud; Hoylaerts Marc F; Pannekoek Hans; van Berkel Theo J C; Kuiper Johan; Biessen Erik A L
Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists.
Blood 2002;100(10):3570-7.
2002: Van Rossenberg Sabine M W; Sliedregt-Bol Karen M; Meeuwenoord Nico J; Van Berkel Theo J C; Van Boom Jacques H; Van Der Marel Gijs A; Biessen Erik A L
Targeted lysosome disruptive elements for improvement of parenchymal liver cell-specific gene delivery.
The Journal of biological chemistry 2002;277(48):45803-10.
2002: Michon Ingrid N; Hauer Arnaud D; von der Thüsen Jan H; Molenaar Tom J M; van Berkel Theo J C; Biessen Erik A L; Kuiper Johan
Targeting of peptides to restenotic vascular smooth muscle cells using phage display in vitro and in vivo.
Biochimica et biophysica acta 2002;1591(1-3):87-97.
2002: Bijsterbosch Martin K; Manoharan Muthiah; Dorland Rick; Van Veghel Richard; Biessen Erik A L; Van Berkel Theo J C
bis-Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides are highly selectively taken up by the liver.
The Journal of pharmacology and experimental therapeutics 2002;302(2):619-26.
2002: Rijken D C; van der Kaaden M E; Groeneveld E; Barrett-Bergshoeff M M; van Berkel Th J C; Kuiper J
Characterization of the binding of urokinase-type plasminogen activator to the asialoglycoprotein receptor.
Thrombosis and haemostasis 2002;88(1):83-8.
2002: Michon Ingrid N; Penning Louis C; Molenaar Tom J M; van Berkel Theo J C; Biessen Erik A L; Kuiper Johan
The effect of TGF-beta receptor binding peptides on smooth muscle cells.
Biochemical and biophysical research communications 2002;293(4):1279-86.
2002: 't Hoen Peter A C; Rooseboom Martijn; Bijsterbosch Martin K; van Berkel Theo J C; Vermeulen Nico P E; Commandeur Jan N M
Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugates.
Biochemical pharmacology 2002;63(10):1843-9.
2002: 't Hoen Peter A C; Rosema Bram-Sieben; Commandeur Jan N M; Vermeulen Nico P E; Manoharan Muthiah; van Berkel Theo J C; Biessen Eric A L; Bijsterbosch Martin K
Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay. Discovery of selective and potent inhibitors of glutathione S-transferase Mu expression.
European journal of biochemistry / FEBS 2002;269(10):2574-83.
2002: von der Thüsen Jan H; van Vlijmen Bart J M; Hoeben Rob C; Kockx Mark M; Havekes Louis M; van Berkel Theo J C; Biessen Erik A L
Induction of atherosclerotic plaque rupture in apolipoprotein E-/- mice after adenovirus-mediated transfer of p53.
Circulation 2002;105(17):2064-70.
2002: van Eck Miranda; Bos I Sophie T; Kaminski Wolfgang E; Orsó Evelyn; Rothe Gregor; Twisk Jaap; Böttcher Alfred; Van Amersfoort Edwin S; Christiansen-Weber Trudy A; Fung-Leung Wai-Ping; Van Berkel Theo J C; Schmitz Gerd
Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6298-303.
2002: Biessen Erik A L; Sliedregt-Bol Karen; 'T Hoen Peter A Chr; Prince Perry; Van der Bilt Erica; Valentijn A Rob P M; Meeuwenoord Nico J; Princen Hans; Bijsterbosch Martin K; Van der Marel Gijs A; Van Boom Jacques H; Van Berkel Theo J C
Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes.
Bioconjugate chemistry 2002;13(2):295-302.
2002: Molenaar Tom J M; Michon Ingrid; de Haas Sonja A M; van Berkel Theo J C; Kuiper Johan; Biessen Erik A L
Uptake and processing of modified bacteriophage M13 in mice: implications for phage display.
Virology 2002;293(1):182-91.
2001: Hoen P A; Bijsterbosch M K; van Berkel T J; Vermeulen N P; Commandeur J N
Midazolam is a phenobarbital-like cytochrome p450 inducer in rats.
The Journal of pharmacology and experimental therapeutics 2001;299(3):921-7.
2001: Von Der Thüsen J H; Kuiper J; Fekkes M L; De Vos P; Van Berkel T J; Biessen E A
Attenuation of atherogenesis by systemic and local adenovirus-mediated gene transfer of interleukin-10 in LDLr-/- mice.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2730-2.
2001: Jong M C; Rensen P C; Dahlmans V E; van der Boom H; van Berkel T J; Havekes L M
Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice.
Journal of lipid research 2001;42(10):1578-85.
2001: Rensen P C; Sliedregt L A; Ferns M; Kieviet E; van Rossenberg S M; van Leeuwen S H; van Berkel T J; Biessen E A
Determination of the upper size limit for uptake and processing of ligands by the asialoglycoprotein receptor on hepatocytes in vitro and in vivo.
The Journal of biological chemistry 2001;276(40):37577-84.
2001: Bijsterbosch M K; Manoharan M; Dorland R; Waarlo I H; Biessen E A; van Berkel T J
Delivery of cholesteryl-conjugated phosphorothioate oligodeoxynucleotides to Kupffer cells by lactosylated low-density lipoprotein.
Biochemical pharmacology 2001;62(5):627-33.
2001: Bijsterbosch M K; Ying C; de Vrueh R L; de Clercq E; Biessen E A; Neyts J; van Berkel T J
Carrier-mediated delivery improves the efficacy of 9-(2-phosphonylmethoxyethyl)adenine against hepatitis B virus.
Molecular pharmacology 2001;60(3):521-7.
2001: van Vlijmen B J; Gerritsen G; Franken A L; Boesten L S; Kockx M M; Gijbels M J; Vierboom M P; van Eck M; van De Water B; van Berkel T J; Havekes L M
Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE*3-Leiden transgenic mice.
Circulation research 2001;88(8):780-6.
2001: Rensen P C; de Vrueh R L; Kuiper J; Bijsterbosch M K; Biessen E A; van Berkel T J
Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting.
Advanced drug delivery reviews 2001;47(2-3):251-76.
2001: van Rossenberg S M; Sliedregt L A; Autar R; Piperi C; Van Der Merwe A P; van Berkel T J; Kuiper J; Biessen E A
A structure-function study of ligand recognition by CD22beta.
The Journal of biological chemistry 2001;276(16):12967-73.
2001: de Vrueh R L; van Berkel T J; Bijsterbosch M K
Cryopreservation enables long-term storage of 9-(2-phosphonylmethoxyethyl)adenine prodrug-loaded reconstituted lactosylated high-density lipoprotein.
Pharmaceutical research 2001;18(3):403-7.
2001: Van Oosten M; Rensen P C; Van Amersfoort E S; Van Eck M; Van Dam A M; Breve J J; Vogel T; Panet A; Van Berkel T J; Kuiper J
Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality. A new therapeutic approach to treat gram-negative sepsis.
The Journal of biological chemistry 2001;276(12):8820-4.
2001: von der Thüsen J H; van Berkel T J; Biessen E A
Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice.
Circulation 2001;103(8):1164-70.
2001: Sliedregt L A; van Rossenberg S M; Autar R; Valentijn A R; van der Marel G A; van Boom J H; Piperi C; van der Merwe P A; Kuiper J; van Berkel T J; Biessen E A
Design and synthesis of a multivalent homing device for targeting to murine CD22.
Bioorganic & medicinal chemistry 2001;9(1):85-97.
2001: Van Eck M; Van Dijk K W; Herijgers N; Hofker M H; Groot P H; Van Berkel T J
Essential role for the (hepatic) LDL receptor in macrophage apolipoprotein E-induced reduction in serum cholesterol levels and atherosclerosis.
Atherosclerosis 2001;154(1):103-12.
2001: van Oosten M; van Amersfoort E S; van Berkel T J; Kuiper J
Scavenger receptor-like receptors for the binding of lipopolysaccharide and lipoteichoic acid to liver endothelial and Kupffer cells.
Journal of endotoxin research 2001;7(5):381-4.
2000: Van Eck M; De Winther M P; Herijgers N; Havekes L M; Hofker M H; Groot P H; Van Berkel T J
Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on cholesterol levels and atherosclerosis in ApoE-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(12):2600-6.
2000: Hoen P A; Commandeur J N; Vermeulen N P; Van Berkel T J; Bijsterbosch M K
Selective induction of cytochrome P450 3A1 by dexamethasone in cultured rat hepatocytes: analysis with a novel reverse transcriptase-polymerase chain reaction assay section sign.
Biochemical pharmacology 2000;60(10):1509-18.
2000: Van Eck M; Zimmermann R; Groot P H; Zechner R; Van Berkel T J
Role of macrophage-derived lipoprotein lipase in lipoprotein metabolism and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(9):E53-62.
2000: Herijgers N; de Winther M P; Van Eck M; Havekes L M; Hofker M H; Hoogerbrugge P M; Van Berkel T J
Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice.
Journal of lipid research 2000;41(9):1402-9.
2000: Biessen E A; Valentijn A R; De Vrueh R L; Van De Bilt E; Sliedregt L A; Prince P; Bijsterbosch M K; Van Boom J H; Van Der Marel G A; Abrahams P J; Van Berkel T J
Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(12):1784-92.
2000: Herijgers N; Van Eck M; Groot P H; Hoogerbrugge P M; Van Berkel T J
Low density lipoprotein receptor of macrophages facilitates atherosclerotic lesion formation in C57Bl/6 mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(8):1961-7.
2000: Terpstra V; van Amersfoort E S; van Velzen A G; Kuiper J; van Berkel T J
Hepatic and extrahepatic scavenger receptors: function in relation to disease.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(8):1860-72.
2000: Bijsterbosch M K; Rump E T; De Vrueh R L; Dorland R; van Veghel R; Tivel K L; Biessen E A; van Berkel T J; Manoharan M
Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation.
Nucleic acids research 2000;28(14):2717-25.
2000: Herijgers N; Van Eck M; Korporaal S J; Hoogerbrugge P M; Van Berkel T J
Relative importance of the LDL receptor and scavenger receptor class B in the beta-VLDL-induced uptake and accumulation of cholesteryl esters by peritoneal macrophages.
Journal of lipid research 2000;41(7):1163-71.
2000: Rump E T; de Vrueh R L; Manoharan M; Waarlo I H; van Veghel R; Biessen E A; van Berkel T J; Bijsterbosch M K
Modification of the plasma clearance and liver uptake of steroid ester-conjugated oligodeoxynucleotides by association with (lactosylated) low-density lipoprotein.
Biochemical pharmacology 2000;59(11):1407-16.
2000: Van Berkel T J; Van Eck M; Herijgers N; Fluiter K; Nion S
Scavenger receptor classes A and B. Their roles in atherogenesis and the metabolism of modified LDL and HDL.
Annals of the New York Academy of Sciences 2000;902():113-26; discussion 126-7.
2000: Van Eck M; Herijgers N; Vidgeon-Hart M; Pearce N J; Hoogerbrugge P M; Groot P H; Van Berkel T J
Accelerated atherosclerosis in C57Bl/6 mice transplanted with ApoE-deficient bone marrow.
Atherosclerosis 2000;150(1):71-80.
2000: Rensen P C; Jong M C; van Vark L C; van der Boom H; Hendriks W L; van Berkel T J; Biessen E A; Havekes L M
Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis.
The Journal of biological chemistry 2000;275(12):8564-71.
2000: Terpstra V; van Berkel T J
Scavenger receptors on liver Kupffer cells mediate the in vivo uptake of oxidatively damaged red blood cells in mice.
Blood 2000;95(6):2157-63.
2000: de Vrueh R L; Rump E T; van De Bilt E; van Veghel R; Balzarini J; Biessen E A; van Berkel T J; Bijsterbosch M K
Carrier-mediated delivery of 9-(2-phosphonylmethoxyethyl)adenine to parenchymal liver cells: a novel therapeutic approach for hepatitis B.
Antimicrobial agents and chemotherapy 2000;44(3):477-83.
2000: Van Eck M; Herijgers N; Van Dijk K W; Havekes L M; Hofker M H; Groot P H; Van Berkel T J
Effect of macrophage-derived mouse ApoE, human ApoE3-Leiden, and human ApoE2 (Arg158-->Cys) on cholesterol levels and atherosclerosis in ApoE-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(1):119-27.
2000: Biessen E A; Vietsch H; Rump E T; Fluiter K; Bijsterbosch M K; van Berkel T J
Targeted delivery of antisense oligonucleotides to parenchymal liver cells in vivo.
Methods in enzymology 2000;314():324-42.
1999: van Vlijmen B J; Rohlmann A; Page S T; Bensadoun A; Bos I S; van Berkel T J; Havekes L M; Herz J
An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins.
The Journal of biological chemistry 1999;274(49):35219-26.
1999: de Vrueh R L; Rump E T; Sliedregt L A; Biessen E A; van Berkel T J; Bijsterbosch M K
Synthesis of a lipophilic prodrug of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and its incorporation into a hepatocyte-specific lipidic carrier.
Pharmaceutical research 1999;16(8):1179-85.
1999: van Velzen A G; Suzuki H; Kodama T; van Berkel T J
The role of scavenger receptor class A in the adhesion of cells is dependent on cell type and cellular activation state.
Experimental cell research 1999;250(1):264-71.
1999: Biessen E A; Vietsch H; Rump E T; Fluiter K; Kuiper J; Bijsterbosch M K; van Berkel T J
Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo.
The Biochemical journal 1999;340 ( Pt 3)():783-92.
1999: de Vries H E; Moor A C; Dubbelman T M; van Berkel T J; Kuiper J
Oxidized low-density lipoprotein as a delivery system for photosensitizers: implications for photodynamic therapy of atherosclerosis.
The Journal of pharmacology and experimental therapeutics 1999;289(1):528-34.
1999: Versluis A J; Rump E T; Rensen P C; van Berkel T J; Bijsterbosch M K
Stable incorporation of a lipophilic daunorubicin prodrug into apolipoprotein E-exposing liposomes induces uptake of prodrug via low-density lipoprotein receptor in vivo.
The Journal of pharmacology and experimental therapeutics 1999;289(1):1-7.
1999: Fluiter K; Sattler W; De Beer M C; Connell P M; van der Westhuyzen D R; van Berkel T J
Scavenger receptor BI mediates the selective uptake of oxidized cholesterol esters by rat liver.
The Journal of biological chemistry 1999;274(13):8893-9.
1999: de Vries H E; Buchner B; van Berkel T J; Kuiper J
Specific interaction of oxidized low-density lipoprotein with macrophage-derived foam cells isolated from rabbit atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(3):638-45.
1999: Sliedregt L A; Rensen P C; Rump E T; van Santbrink P J; Bijsterbosch M K; Valentijn A R; van der Marel G A; van Boom J H; van Berkel T J; Biessen E A
Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor.
Journal of medicinal chemistry 1999;42(4):609-18.
1999: van Dijk K W; van Vlijmen B J; van't Hof H B; van der Zee A; Santamarina-Fojo S; van Berkel T J; Havekes L M; Hofker M H
In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE.
Journal of lipid research 1999;40(2):336-44.
1998: Versluis A J; Rensen P C; Rump E T; Van Berkel T J; Bijsterbosch M K
Low-density lipoprotein receptor-mediated delivery of a lipophilic daunorubicin derivative to B16 tumours in mice using apolipoprotein E-enriched liposomes.
British journal of cancer 1998;78(12):1607-14.
1998: van Oosten M; van de Bilt E; van Berkel T J; Kuiper J
New scavenger receptor-like receptors for the binding of lipopolysaccharide to liver endothelial and Kupffer cells.
Infection and immunity 1998;66(11):5107-12.
1998: Bijsterbosch M K; Smeijsters L J; van Berkel T J
Disposition of the acyclic nucleoside phosphonate (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine.
Antimicrobial agents and chemotherapy 1998;42(5):1146-50.
1998: Rump E T; de Vrueh R L; Sliedregt L A; Biessen E A; van Berkel T J; Bijsterbosch M K
Preparation of conjugates of oligodeoxynucleotides and lipid structures and their interaction with low-density lipoprotein.
Bioconjugate chemistry 1998;9(3):341-9.
1998: Versluis A J; Rump E T; Rensen P C; Van Berkel T J; Bijsterbosch M K
Synthesis of a lipophilic daunorubicin derivative and its incorporation into lipidic carriers developed for LDL receptor-mediated tumor therapy.
Pharmaceutical research 1998;15(4):531-7.
1998: Fluiter K; van der Westhuijzen D R; van Berkel T J
In vivo regulation of scavenger receptor BI and the selective uptake of high density lipoprotein cholesteryl esters in rat liver parenchymal and Kupffer cells.
The Journal of biological chemistry 1998;273(14):8434-8.
1998: Van Berkel T J; Van Velzen A; Kruijt J K; Suzuki H; Kodama T
Uptake and catabolism of modified LDL in scavenger-receptor class A type I/II knock-out mice.
The Biochemical journal 1998;331 ( Pt 1)():29-35.
1998: De Vries H E; Ronken E; Reinders J H; Buchner B; Van Berkel T J; Kuiper J
Acute effects of oxidized low density lipoprotein on metabolic responses in macrophages.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(1):111-8.
1997: Van Eck M; Herijgers N; Yates J; Pearce N J; Hoogerbrugge P M; Groot P H; Van Berkel T J
Bone marrow transplantation in apolipoprotein E-deficient mice. Effect of ApoE gene dosage on serum lipid concentrations, (beta)VLDL catabolism, and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):3117-26.
1997: van der Kooij M A; von der Mark E M; Kruijt J K; van Velzen A; van Berkel T J; Morand O H
Human monocyte-derived macrophages express an approximately 120-kD Ox-LDL binding protein with strong identity to CD68.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):3107-16.
1997: Noorman F; Barrett-Bergshoeff M M; Biessen E A; van de Bilt E; van Berkel T J; Rijken D C
Cluster mannosides can inhibit mannose receptor-mediated tissue-type plasminogen activator degradation by both rat and human cells.
Hepatology (Baltimore, Md.) 1997;26(5):1303-10.
1997: Herijgers N; Van Eck M; Groot P H; Hoogerbrugge P M; Van Berkel T J
Effect of bone marrow transplantation on lipoprotein metabolism and atherosclerosis in LDL receptor-knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(10):1995-2003.
1997: Fluiter K; van Berkel T J
Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal liver cells.
The Biochemical journal 1997;326 ( Pt 2)():515-9.
1997: Rensen P C; Schiffelers R M; Versluis A J; Bijsterbosch M K; Van Kuijk-Meuwissen M E; Van Berkel T J
Human recombinant apolipoprotein E-enriched liposomes can mimic low-density lipoproteins as carriers for the site-specific delivery of antitumor agents.
Molecular pharmacology 1997;52(3):445-55.
1997: Bijsterbosch M K; Manoharan M; Rump E T; De Vrueh R L; van Veghel R; Tivel K L; Biessen E A; Bennett C F; Cook P D; van Berkel T J
In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells.
Nucleic acids research 1997;25(16):3290-6.
1997: de Vries H E; Kuiper J; de Boer A G; Van Berkel T J; Breimer D D
The blood-brain barrier in neuroinflammatory diseases.
Pharmacological reviews 1997;49(2):143-55.
1997: Rensen P C; Herijgers N; Netscher M H; Meskers S C; van Eck M; van Berkel T J
Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo.
Journal of lipid research 1997;38(6):1070-84.
1997: van der Kaaden M E; Rijken D C; Kruijt J K; van Berkel T J; Kuiper J
The role of the low-density lipoprotein receptor-related protein (LRP) in the plasma clearance and liver uptake of recombinant single-chain urokinase-type plasminogen activator in rats.
Thrombosis and haemostasis 1997;77(4):710-7.
1997: Van Velzen A G; Da Silva R P; Gordon S; Van Berkel T J
Characterization of a receptor for oxidized low-density lipoproteins on rat Kupffer cells: similarity to macrosialin.
The Biochemical journal 1997;322 ( Pt 2)():411-5.
1997: Biessen E A; van Teijlingen M; Vietsch H; Barrett-Bergshoeff M M; Bijsterbosch M K; Rijken D C; van Berkel T J; Kuiper J
Antagonists of the mannose receptor and the LDL receptor-related protein dramatically delay the clearance of tissue plasminogen activator.
Circulation 1997;95(1):46-52.
1997: Biessen E A; Sliedregt L A; Van Berkel T J
Approaches for the design of novel anti-atherogenic compounds.
Sub-cellular biochemistry 1997;28():507-39.
1996: Ziere G J; van der Kaaden M E; Vogelezang C J; Boers W; Bihain B E; Kuiper J; Kruijt J K; van Berkel T J
Blockade of the alpha 2-macroglobulin receptor/low-density-lipoprotein-receptor-related protein on rat liver parenchymal cells by the 39-kDa receptor-associated protein leaves the interaction of beta-migrating very-low-density lipoprotein with the lipoprotein remnant receptor unaffected.
European journal of biochemistry / FEBS 1996;242(3):703-11.
1996: Biessen E A; Vietsch H; van Berkel T J
Induction of hepatic uptake of lipoprotein(a) by cholesterol-derivatized cluster galactosides.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(12):1552-8.
1996: Biessen E A; Noorman F; van Teijlingen M E; Kuiper J; Barrett-Bergshoeff M; Bijsterbosch M K; Rijken D C; van Berkel T J
Lysine-based cluster mannosides that inhibit ligand binding to the human mannose receptor at nanomolar concentration.
The Journal of biological chemistry 1996;271(45):28024-30.
1996: Fluiter K; Vietsch H; Biessen E A; Kostner G M; van Berkel T J; Sattler W
Increased selective uptake in vivo and in vitro of oxidized cholesteryl esters from high-density lipoprotein by rat liver parenchymal cells.
The Biochemical journal 1996;319 ( Pt 2)():471-6.
1996: Rensen P C; de Vrueh R L; van Berkel T J
Targeting hepatitis B therapy to the liver. Clinical pharmacokinetic considerations.
Clinical pharmacokinetics 1996;31(2):131-55.
1996: Versluis A J; van Geel P J; Oppelaar H; van Berkel T J; Bijsterbosch M K
Receptor-mediated uptake of low-density lipoprotein by B16 melanoma cells in vitro and in vivo in mice.
British journal of cancer 1996;74(4):525-32.
1996: Bijsterbosch M K; van de Bilt H; van Berkel T J
Specific targeting of a lipophilic prodrug of iododeoxyuridine to parenchymal liver cells using lactosylated reconstituted high density lipoprotein particles.
Biochemical pharmacology 1996;52(1):113-21.
1996: van Berkel T J; Bihain B E; Ziere G J; Kruyt J K; Bijsterbosch M K; Kuiper J
Ligand specificity of the LDL-receptor related protein.
Zeitschrift für Gastroenterologie 1996;34 Suppl 3():116-7.
1996: de Vries H E; Blom-Roosemalen M C; de Boer A G; van Berkel T J; Breimer D D; Kuiper J
Effect of endotoxin on permeability of bovine cerebral endothelial cell layers in vitro.
The Journal of pharmacology and experimental therapeutics 1996;277(3):1418-23.
1996: Rensen P C; van Berkel T J
Apolipoprotein E effectively inhibits lipoprotein lipase-mediated lipolysis of chylomicron-like triglyceride-rich lipid emulsions in vitro and in vivo.
The Journal of biological chemistry 1996;271(25):14791-9.
1996: Bijsterbosch M K; Donker W; van de Bilt H; van Weely S; van Berkel T J; Aerts J M
Quantitative analysis of the targeting of mannose-terminal glucocerebrosidase. Predominant uptake by liver endothelial cells.
European journal of biochemistry / FEBS 1996;237(2):344-9.
1996: Kuiper J; Van't Hof A; Otter M; Biessen E A; Rijken D C; van Berkel T J
Interaction of mutants of tissue-type plasminogen activator with liver cells: effect of domain deletions.
The Biochemical journal 1996;313 ( Pt 3)():775-80.
1996: de Vries H E; Blom-Roosemalen M C; van Oosten M; de Boer A G; van Berkel T J; Breimer D D; Kuiper J
The influence of cytokines on the integrity of the blood-brain barrier in vitro.
Journal of neuroimmunology 1996;64(1):37-43.
1996: van der Kooij M A; Morand O H; Kempen H J; van Berkel T J
Decrease in scavenger receptor expression in human monocyte-derived macrophages treated with granulocyte macrophage colony-stimulating factor.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(1):106-14.
1996: Ziere G J; Kruijt J K; Bijsterbosch M K; van Berkel T J
Recognition of lactoferrin and aminopeptidase M-modified lactoferrin by the liver: involvement of proteoglycans and the remnant receptor.
The Biochemical journal 1996;313 ( Pt 1)():289-95.
1995: van Berkel T J; Fluiter K; van Velzen A G; Vogelezang C J; Ziere G J
LDL receptor-independent and -dependent uptake of lipoproteins.
Atherosclerosis 1995;118 Suppl():S43-50.
1995: de Vries H E; Eppens E F; Prins M; Kuiper J; van Berkel T J; de Boer A G; Breimer D D
Transport of a hydrophilic compound into the cerebrospinal fluid during experimental allergic encephalomyelitis and after lipopolysaccharide administration.
Pharmaceutical research 1995;12(12):1932-6.
1995: Kuiper J; van de Bilt H; Martin U; van Berkel T J
Uptake, internalization and degradation of the novel plasminogen activator reteplase (BM 06.022) in the rat.
Thrombosis and haemostasis 1995;74(6):1501-10.
1995: De Rijke Y B; Verwey H F; Vogelezang C J; Van Der Velde E A; Princen H M; Van Der Laarse A; Bruschke A V; Van Berkel T J
Enhanced susceptibility of low-density lipoproteins to oxidation in coronary bypass patients with progression of atheroscerosis.
Clinica chimica acta; international journal of clinical chemistry 1995;243(2):137-49.
1995: Kuiper J; Otter M; Voorschuur A H; van Zonneveld A J; Rijken D C; van Berkel T J
Characterization of the interaction of a complex of tissue-type plasminogen activator and plasminogen activator inhibitor type 1 with rat liver cells.
Thrombosis and haemostasis 1995;74(5):1298-304.
1995: van Oosten M; van de Bilt E; de Vries H E; van Berkel T J; Kuiper J
Vascular adhesion molecule-1 and intercellular adhesion molecule-1 expression on rat liver cells after lipopolysaccharide administration in vivo.
Hepatology (Baltimore, Md.) 1995;22(5):1538-46.
1995: van der Kaaden M E; Rijken D C; Groeneveld E; van Berkel T J; Kuiper J
Native and non-glycosylated recombinant single-chain urokinase-type plasminogen activator are recognized by different receptor systems on rat parenchymal liver cells.
Thrombosis and haemostasis 1995;74(2):722-9.
1995: Voorschuur A H; Kuiper J; Van Noort W L; Van Berkel T J
Zonal distribution of receptor binding of trypsin-activated alpha 2-macroglobulin, alpha 2-macroglobulin receptor-associated protein, lactoferrin and transferrin on rat liver parenchymal cells.
Biochimica et biophysica acta 1995;1257(3):288-92.
1995: de Vries H E; Breedveld B; Kuiper J; de Boer A G; Van Berkel T J; Breimer D D
High-density lipoprotein and cerebral endothelial cells in vitro: interactions and transport.
Biochemical pharmacology 1995;50(2):271-3.
1995: de Vries H E; Hoogendoorn K H; van Dijk J; Zijlstra F J; van Dam A M; Breimer D D; van Berkel T J; de Boer A G; Kuiper J
Eicosanoid production by rat cerebral endothelial cells: stimulation by lipopolysaccharide, interleukin-1 and interleukin-6.
Journal of neuroimmunology 1995;59(1-2):1-8.
1995: Biessen E A; Broxterman H; van Boom J H; van Berkel T J
The cholesterol derivative of a triantennary galactoside with high affinity for hepatic asialoglycoprotein receptor: a potent cholesterol lowering agent.
Journal of medicinal chemistry 1995;38(11):1846-52.
1995: Biessen E A; Beuting D M; Roelen H C; van de Marel G A; van Boom J H; van Berkel T J
Synthesis of cluster galactosides with high affinity for the hepatic asialoglycoprotein receptor.
Journal of medicinal chemistry 1995;38(9):1538-46.
1995: Biessen E A; Vietsch H; Van Berkel T J
Cholesterol derivative of a new triantennary cluster galactoside lowers serum cholesterol levels and enhances secretion of bile acids in the rat.
Circulation 1995;91(6):1847-54.
1995: Rensen P C; van Dijk M C; Havenaar E C; Bijsterbosch M K; Kruijt J K; van Berkel T J
Selective liver targeting of antivirals by recombinant chylomicrons--a new therapeutic approach to hepatitis B.
Nature medicine 1995;1(3):221-5.
1994: De Rijke Y B; Biessen E A; Vogelezang C J; van Berkel T J
Binding characteristics of scavenger receptors on liver endothelial and Kupffer cells for modified low-density lipoproteins.
The Biochemical journal 1994;304 ( Pt 1)():69-73.
1994: Bijsterbosch M K; Schouten D; van Berkel T J
Synthesis of the dioleoyl derivative of iododeoxyuridine and its incorporation into reconstituted high density lipoprotein particles.
Biochemistry 1994;33(47):14073-80.
1994: Biessen E A; Beuting D M; Vietsch H; Bijsterbosch M K; Van Berkel T J
Specific targeting of the antiviral drug 5-iodo 2'-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine.
Journal of hepatology 1994;21(5):806-15.
1994: Voorschuur A H; Kuiper J; Neelissen J A; Boers W; Van Berkel T J
Different zonal distribution of the asialoglycoprotein receptor, the alpha 2-macroglobulin receptor/low-density-lipoprotein receptor-related protein and the lipoprotein-remnant receptor of rat liver parenchymal cells.
The Biochemical journal 1994;303 ( Pt 3)():809-16.
1994: van Berkel T J; Ziere G J; Bijsterbosch M K; Kuiper J
Lipoprotein receptors and atherogenic receptor-mediated mechanisms.
Current opinion in lipidology 1994;5(5):331-8.
1994: Boers W; Linthorst C; van Dijk M C; van Berkel T J
Uptake of methylamine-activated alpha 2-macroglobulin by rat liver.
Annals of the New York Academy of Sciences 1994;737():428-30.
1994: Biessen E A; Vietsch H; Van Berkel T J
Cholesterol derivative of a new triantennary cluster galactoside directs low- and high-density lipoproteins to the parenchymal liver cell.
The Biochemical journal 1994;302 ( Pt 1)():283-9.
1994: Pieters M N; Esbach S; Schouten D; Brouwer A; Knook D L; Van Berkel T J
Cholesteryl esters from oxidized low-density lipoproteins are in vivo rapidly hydrolyzed in rat Kupffer cells and transported to liver parenchymal cells and bile.
Hepatology (Baltimore, Md.) 1994;19(6):1459-67.
1994: de Vries H E; Moor A C; Blom-Roosemalen M C; de Boer A G; Breimer D D; van Berkel T J; Kuiper J
Lymphocyte adhesion to brain capillary endothelial cells in vitro.
Journal of neuroimmunology 1994;52(1):1-8.
1994: van de Water B; van Berkel T J; Kuiper J
Activation of rat Kupffer cells to tumoricidal cells by the immunomodulator muramyl tripeptide-phosphatidylethanolamine incorporated into the novel drug carrier lactosylated low density lipoprotein.
Molecular pharmacology 1994;45(5):971-7.
1994: Biessen E A; Bakkeren H F; Beuting D M; Kuiper J; Van Berkel T J
Ligand size is a major determinant of high-affinity binding of fucose- and galactose-exposing (lipo)proteins by the hepatic fucose receptor.
The Biochemical journal 1994;299 ( Pt 1)():291-6.
1994: Kuiper J; Bakkeren H F; Biessen E A; Van Berkel T J
Characterization of the interaction of galactose-exposing particles with rat Kupffer cells.
The Biochemical journal 1994;299 ( Pt 1)():285-90.
1994: de Rijke Y B; van Berkel T J
Rat liver Kupffer and endothelial cells express different binding proteins for modified low density lipoproteins. Kupffer cells express a 95-kDa membrane protein as a specific binding site for oxidized low density lipoproteins.
The Journal of biological chemistry 1994;269(2):824-7.
1994: Pieters M N; Schouten D; Van Berkel T J
In vitro and in vivo evidence for the role of HDL in reverse cholesterol transport.
Biochimica et biophysica acta 1994;1225(2):125-34.
1994: Esbach S; Stins M F; Brouwer A; Roholl P J; van Berkel T J; Knook D L
Morphological characterization of scavenger receptor-mediated processing of modified lipoproteins by rat liver endothelial cells.
Experimental cell research 1994;210(1):62-70.
1993: Ziere G J; Bijsterbosch M K; van Berkel T J
Removal of 14 N-terminal amino acids of lactoferrin enhances its affinity for parenchymal liver cells and potentiates the inhibition of beta- very low density lipoprotein binding.
The Journal of biological chemistry 1993;268(36):27069-75.
1993: de Vries H E; Kuiper J; de Boer A G; van Berkel T J; Breimer D D
Characterization of the scavenger receptor on bovine cerebral endothelial cells in vitro.
Journal of neurochemistry 1993;61(5):1813-21.
1993: Esbach S; Pieters M N; van der Boom J; Schouten D; van der Heyde M N; Roholl P J; Brouwer A; van Berkel T J; Knook D L
Visualization of the uptake and processing of oxidized low-density lipoproteins in human and rat liver.
Hepatology (Baltimore, Md.) 1993;18(3):537-45.
1993: Schouten D; van der Kooij M; Muller J; Pieters M N; Bijsterbosch M K; van Berkel T J
Development of lipoprotein-like lipid particles for drug targeting: neo-high density lipoproteins.
Molecular pharmacology 1993;44(2):486-92.
1993: Pieters M N; Castro G R; Schouten D; Duchateau P; Fruchart J C; Van Berkel T J
Cholesterol esters selectively delivered in vivo by high-density-lipoprotein subclass LpA-I to rat liver are processed faster into bile acids than are LpA-I/A-II-derived cholesterol esters.
The Biochemical journal 1993;292 ( Pt 3)():819-23.
1993: Kamps J A; van Berkel T J
Regulation of low-density-lipoprotein receptors in the human hepatoma cell line Hep G2. Effect of phorbol 12-myristate 13-acetate and low-density lipoprotein.
European journal of biochemistry / FEBS 1993;213(3):989-94.
1993: Mulder M; Lombardi P; Jansen H; van Berkel T J; Frants R R; Havekes L M
Low density lipoprotein receptor internalizes low density and very low density lipoproteins that are bound to heparan sulfate proteoglycans via lipoprotein lipase.
The Journal of biological chemistry 1993;268(13):9369-75.
1993: de Smidt P C; Versluis A J; van Berkel T J
Properties of incorporation, redistribution, and integrity of porphyrin-low-density lipoprotein complexes.
Biochemistry 1993;32(11):2916-22.
1993: van Dijk M C; Pieters M; van Berkel T J
Kinetics of biliary secretion of chylomicron remnant cholesterol (esters) in the rat.
European journal of biochemistry / FEBS 1993;211(3):781-7.
1992: Bijsterbosch M K; Bakkeren H F; Kempen H J; Roelen H C; van Boom J H; van Berkel T J
A monogalactosylated cholesterol derivative that specifically induces uptake of LDL by the liver.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(10):1153-60.
1992: van Dijk M C; Boers W; Linthorst C; van Berkel T J
Role of the scavenger receptor in the uptake of methylamine-activated alpha 2-macroglobulin by rat liver.
The Biochemical journal 1992;287 ( Pt 2)():447-55.
1992: Kamps J A; Kruijt J K; Kuiper J; van Berkel T J
Characterization of the interaction of acetylated LDL and oxidatively modified LDL with human liver parenchymal and Kupffer cells in culture.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(9):1079-87.
1992: van Dijk M C; Kruijt J K; Boers W; Linthorst C; van Berkel T J
Distinct properties of the recognition sites for beta-very low density lipoprotein (remnant receptor) and alpha 2-macroglobulin (low density lipoprotein receptor-related protein) on rat parenchymal cells.
The Journal of biological chemistry 1992;267(25):17732-7.
1992: de Rijke Y B; Jürgens G; Hessels E M; Hermann A; van Berkel T J
In vivo fate and scavenger receptor recognition of oxidized lipoprotein[a] isoforms in rats.
Journal of lipid research 1992;33(9):1315-25.
1992: Otter M; Zocková P; Kuiper J; van Berkel T J; Barrett-Bergshoeff M M; Rijken D C
Isolation and characterization of the mannose receptor from human liver potentially involved in the plasma clearance of tissue-type plasminogen activator.
Hepatology (Baltimore, Md.) 1992;16(1):54-9.
1992: de Smidt P C; Versluis A J; van Berkel T J
Transport of sulfonated tetraphenylporphine by lipoproteins in the hamster.
Biochemical pharmacology 1992;43(12):2567-73.
1992: Ziere G J; van Dijk M C; Bijsterbosch M K; van Berkel T J
Lactoferrin uptake by the rat liver. Characterization of the recognition site and effect of selective modification of arginine residues.
The Journal of biological chemistry 1992;267(16):11229-35.
1992: Kamps J A; van Berkel T J
Complete down-regulation of low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2 by beta-migrating very-low-density lipoprotein and non-lipoprotein cholesterol. Different cellular regulatory pools of cholesterol.
European journal of biochemistry / FEBS 1992;206(3):973-8.
1992: de Smidt P C; van Berkel T J
Characteristics of association of oleoyl derivatives of 5-fluorodeoxyuridine and methotrexate with low-density lipoproteins (LDL).
Pharmaceutical research 1992;9(4):565-9.
1992: van Dijk M C; Ziere G J; van Berkel T J
Characterization of the chylomicron-remnant-recognition sites on parenchymal and Kupffer cells of rat liver. Selective inhibition of parenchymal cell recognition by lactoferrin.
European journal of biochemistry / FEBS 1992;205(2):775-84.
1992: De Water R; Kamps J A; Van Dijk M C; Hessels E A; Kuiper J; Kruijt J K; Van Berkel T J
Characterization of the low-density-lipoprotein-receptor-independent interaction of beta-very-low-density lipoprotein with rat and human parenchymal liver cells in vitro.
The Biochemical journal 1992;282 ( Pt 1)():41-8.
1992: Bijsterbosch M K; Van Berkel T J
Lactosylated high density lipoprotein: a potential carrier for the site-specific delivery of drugs to parenchymal liver cells.
Molecular pharmacology 1992;41(2):404-11.
1992: de Rijke Y B; Hessels E M; van Berkel T J
Recognition sites on rat liver cells for oxidatively modified beta-very low density lipoproteins.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(1):41-9.
1992: Kuiper J; Rijken D C; de Munk G A; van Berkel T J
In vivo and in vitro interaction of high and low molecular weight single-chain urokinase-type plasminogen activator with rat liver cells.
The Journal of biological chemistry 1992;267(3):1589-95.
1991: Pieters M N; Schouten D; Bakkeren H F; Esbach B; Brouwer A; Knook D L; van Berkel T J
Selective uptake of cholesteryl esters from apolipoprotein-E-free high-density lipoproteins by rat parenchymal cells in vivo is efficiently coupled to bile acid synthesis.
The Biochemical journal 1991;280 ( Pt 2)():359-65.
1991: Bijsterbosch M K; Bernini F; Bakkeren H F; Gotto A M; Smith L C; van Berkel T J
Enhanced hepatic uptake and processing of cholesterol esters from low density lipoprotein by specific lactosaminated Fab fragments.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(6):1806-13.
1991: van Dijk M C; Ziere G J; Boers W; Linthorst C; Bijsterbosch M K; van Berkel T J
Recognition of chylomicron remnants and beta-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver alpha 2-macroglobulin-recognition site.
The Biochemical journal 1991;279 ( Pt 3)():863-70.
1991: de Smidt P C; Le Doan T; de Falco S; van Berkel T J
Association of antisense oligonucleotides with lipoproteins prolongs the plasma half-life and modifies the tissue distribution.
Nucleic acids research 1991;19(17):4695-700.
1991: Kamps J A; Kuiper J; Kruijt J K; van Berkel T J
Complete down-regulation of low-density lipoprotein receptor activity in human liver parenchymal cells by beta-very-low-density lipoprotein.
FEBS letters 1991;287(1-2):34-8.
1991: Kleinherenbrink-Stins M F; van de Boom J H; Schouten D; Roholl P J; Niels van der Heyde M; Brouwer A; van Berkel T J; Knook D L
Visualization of the interaction of native and modified lipoproteins with parenchymal, endothelial and Kupffer cells from human liver.
Hepatology (Baltimore, Md.) 1991;14(1):79-90.
1991: Kamps J A; Kruijt J K; Kuiper J; Van Berkel T J
Uptake and degradation of human low-density lipoprotein by human liver parenchymal and Kupffer cells in culture.
The Biochemical journal 1991;276 ( Pt 1)():135-40.
1991: Roelen H C; Bijsterbosch M K; Bakkeren H F; van Berkel T J; Kempen H J; Buytenhek M; van der Marel G A; van Boom J H
Water-soluble cholesteryl-containing phosphorothioate monogalactosides: synthesis, properties, and use in lowering blood cholesterol by directing plasma lipoproteins to the liver.
Journal of medicinal chemistry 1991;34(3):1036-42.
1991: Van Berkel T J; De Rijke Y B; Kruijt J K
Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells.
The Journal of biological chemistry 1991;266(4):2282-9.
1991: de Falco S; Boutorine A; de Smidt C; van Berkel T; Saison E; Hélène C; Le Doan T
Utilization of antisense oligonucleotides in vivo: stability and internalization of hydrophobized oligonucleotides.
Nucleic acids symposium series 1991;(24):157-8.
1991: Van Berkel T J; Kruijt J K; De Smidt P C; Bijsterbosch M K
Receptor-dependent targeting of lipoproteins to specific cell types of the liver.
Targeted diagnosis and therapy 1991;5():225-49.
1990: de Smidt P C; van Berkel T J
Prolonged serum half-life of antineoplastic drugs by incorporation into the low density lipoprotein.
Cancer research 1990;50(23):7476-82.
1990: Schouten D; Kleinherenbrink-Stins M F; Brouwer A; Knook D L; Kamps J A; Kuiper J; van Berkel T J
Characterization in vitro of interaction of human apolipoprotein E-free high density lipoprotein with human hepatocytes.
Arteriosclerosis (Dallas, Tex.) 1990;10(6):1127-35.
1990: van Berkel T J; de Smidt P C; van Dijk M C; Ziere G J; Bijsterbosch M K
Drug targeting by endogenous transport vehicles.
Biochemical Society transactions 1990;18(5):748-50.
1990: De Water R; Hessels E M; Bakkeren H F; Van Berkel T J
Hepatic processing and biliary secretion of the cholesteryl esters from beta very-low-density lipoproteins in the rat.
European journal of biochemistry / FEBS 1990;192(2):419-25.
1990: Quax P H; van den Hoogen C M; Verheijen J H; Padro T; Zeheb R; Gelehrter T D; van Berkel T J; Kuiper J; Emeis J J
Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type 1 mRNA in rat tissues in vivo.
The Journal of biological chemistry 1990;265(26):15560-3.
1990: Bijsterbosch M K; Van Berkel T J
Uptake of lactosylated low-density lipoprotein by galactose-specific receptors in rat liver.
The Biochemical journal 1990;270(1):233-9.
1990: Kleinherenbrink-Stins M F; van der Boom J; Bakkeren H F; Roholl P J; Brouwer A; van Berkel T J; Knook D L
Light- and immunoelectron microscopic visualization of in vivo endocytosis of low density lipoprotein by hepatocytes and Kupffer cells in rat liver.
Laboratory investigation; a journal of technical methods and pathology 1990;63(1):73-86.
1990: Bakkeren H F; Kuipers F; Vonk R J; Van Berkel T J
Evidence for reverse cholesterol transport in vivo from liver endothelial cells to parenchymal cells and bile by high-density lipoprotein.
The Biochemical journal 1990;268(3):685-91.
1990: Boogaard P J; Zoeteweij J P; van Berkel T J; van't Noordende J M; Mulder G J; Nagelkerke J F
Primary culture of proximal tubular cells from normal rat kidney as an in vitro model to study mechanisms of nephrotoxicity. Toxicity of nephrotoxicants at low concentrations during prolonged exposure.
Biochemical pharmacology 1990;39(8):1335-45.
1990: de Smidt P C; van Berkel T J
LDL-mediated drug targeting.
Critical reviews in therapeutic drug carrier systems 1990;7(2):99-120.
1990: De Smidt P C; Bijsterbosch M K; Van Berkel T J
LDL as a carrier in site-specific drug delivery.
Targeted diagnosis and therapy 1990;3():355-83.
1990: Rijken D C; Otter M; Kuiper J; van Berkel T J
Receptor-mediated endocytosis of tissue-type plasminogen activator (t-PA) by liver cells.
Thrombosis research. Supplement 1990;10():63-71.
1989: Bijsterbosch M K; Ziere G J; Van Berkel T J
Lactosylated low density lipoprotein: a potential carrier for the site-specific delivery of drugs to Kupffer cells.
Molecular pharmacology 1989;36(3):484-9.
1989: Otter M; Van Berkel T J; Rijken D C
Binding and degradation of tissue-type plasminogen activator by the human hepatoma cell line Hep G2.
Thrombosis and haemostasis 1989;62(2):667-72.
1989: Kuiper J; Zijlstra F J; Kamps J A; Van Berkel T J
Cellular communication inside the liver. Binding, conversion and metabolic effect of prostaglandin D2 on parenchymal liver cells.
The Biochemical journal 1989;262(1):195-201.
1989: Kleinherenbrink-Stins M F; Schouten D; van der Boom J; Brouwer A; Knook D L; van Berkel T J
Nitrosylated high density lipoprotein is recognized by a scavenger receptor in rat liver.
Journal of lipid research 1989;30(4):511-20.
1989: Kuiper J; Kamps J A; Van Berkel T J
Induction of ornithine decarboxylase in rat liver by phorbol ester is mediated by prostanoids from Kupffer cells.
The Journal of biological chemistry 1989;264(12):6874-8.
1989: Harkes L; van Duijne A; van Berkel T J
Interaction of beta-very-low-density lipoproteins with rat liver cells.
European journal of biochemistry / FEBS 1989;180(1):241-8.
1989: Kuiper J; Kamps J A; Van Berkel T J
Identification of the inhibitor of the plasminogen activator as the major protein secreted by endothelial rat liver cells.
FEBS letters 1989;245(1-2):229-34.
1989: Kuipers F; Nagelkerke J F; Bakkeren H; Havinga R; Van Berkel T J; Vonk R J
Processing of cholesteryl ester from low-density lipoproteins in the rat. Hepatic metabolism and biliary secretion after uptake by different hepatic cell types.
The Biochemical journal 1989;257(3):699-704.
1989: Kuiper J; Casteleyn E; van Berkel T J
The role of prostaglandins in endotoxin stimulated glycogenolysis in the liver.
Agents and actions 1989;26(1-2):201-2.
1988: Schouten D; Kleinherenbrink-Stins M; Brouwer A; Knook D L; Van Berkel T J
Interaction in vivo and in vitro of apolipoprotein E-free high-density lipoprotein with parenchymal, endothelial and Kupffer cells from rat liver.
The Biochemical journal 1988;256(2):615-21.
1988: Kuiper J; De Rijke Y B; Zijlstra F J; Van Waas M P; Van Berkel T J
The induction of glycogenolysis in the perfused liver by platelet activating factor is mediated by prostaglandin D2 from Kupffer cells.
Biochemical and biophysical research communications 1988;157(3):1288-95.
1988: Kuiper J; Otter M; Rijken D C; van Berkel T J
Characterization of the interaction in vivo of tissue-type plasminogen activator with liver cells.
The Journal of biological chemistry 1988;263(34):18220-4.
1988: Casteleijn E; Kuiper J; Van Rooij H C; Koster J F; Van Berkel T J
Conditioned media of Kupffer and endothelial liver cells influence protein phosphorylation in parenchymal liver cells. Involvement of prostaglandins.
The Biochemical journal 1988;252(2):601-5.
1988: Casteleijn E; Kuiper J; Van Rooij H C; Kamps J A; Koster J F; Van Berkel T J
Endotoxin stimulates glycogenolysis in the liver by means of intercellular communication.
The Journal of biological chemistry 1988;263(15):6953-5.
1988: Kuiper J; Zijlstra F J; Kamps J A; van Berkel T J
Identification of prostaglandin D2 as the major eicosanoid from liver endothelial and Kupffer cells.
Biochimica et biophysica acta 1988;959(2):143-52.
1988: Casteleijn E; Kuiper J; van Rooij H C; Kamps J A; Koster J F; van Berkel T J
Hormonal control of glycogenolysis in parenchymal liver cells by Kupffer and endothelial liver cells.
The Journal of biological chemistry 1988;263(6):2699-703.
1988: Casteleijn E; Kuiper J; Van Rooij H C; Kamps J A; Koster J F; Van Berkel T J
Prostaglandin D2 mediates the stimulation of glycogenolysis in the liver by phorbol ester.
The Biochemical journal 1988;250(1):77-80.
1988: Harkes L; Jürgens G; Holasek A; van Berkel T J
In vivo studies on the binding sites for lipoprotein (a) on parenchymal and non-parenchymal rat liver cells.
FEBS letters 1988;227(1):27-31.
1988: van Berkel T J; Kuipers F; Nagelkerke J F; Bakkeren H F; Havinga R; Vonk R J
Processing of cholesteryl ester from low density lipoproteins in the rat: hepatic metabolism and biliary excretion after uptake by different hepatic cells.
Agents and actions. Supplements 1988;26():99-107.
1988: Kuiper J; Casteleyn E; Van Berkel T J
Regulation of liver metabolism by intercellular communication.
Advances in enzyme regulation 1988;27():193-208.
1987: van Berkel T J; Dekker C J; Kruijt J K; van Eijk H G
The interaction in vivo of transferrin and asialotransferrin with liver cells.
The Biochemical journal 1987;243(3):715-22.
1986: Nagelkerke J F; Bakkeren H F; Kuipers F; Vonk R J; van Berkel T J
Hepatic processing of the cholesteryl ester from low density lipoprotein in the rat.
The Journal of biological chemistry 1986;261(19):8908-13.
1986: Casteleijn E; van Rooij H C; van Berkel T J; Koster J F
Mechanism of glucagon stimulation of fructose-1,6-bisphosphatase in rat hepatocytes. Involvement of a low-Mr activator.
FEBS letters 1986;201(2):193-7.
1985: Nagelkerke J F; Bakkeren H F; van Berkel T J
Differences in processing of cholesterol between rat liver endothelial cells and rat peritoneal macrophages.
FEBS letters 1985;192(2):279-82.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Theo van Berkel

Research Profile (preview)

Anatomy

Living Beings

Chemicals & Drugs

Disorders

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Theo van Berkel (preview)

All Publications