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Serge Van Calenbergh

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Martijn D P Risseeuw; Davy Sinnaeve; Jan Tavernier; Dries J H De Clercq; Ulrik Hillaert; Sam Lievens; José C Martins; Freya Van den Broeck; Serge Van Calenbergh
A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT.
Višnja Popović; Serge Van Calenbergh; Arne Heyerick; Izet Karalić; Marjan Niketić; Silvana Petrović; Dieter Deforce
Sesquiterpene lactones from the extracts of two Balkan endemic Laserpitium species and their cytotoxic activity.
Gilles Brackman; Abed Al Aziz Al Quntar; Claes D Enk; Izet Karalic; Hans J Nelis; Morris Srebnik; Serge Van Calenbergh; Tom Coenye
Synthesis and evaluation of thiazolidinedione and dioxazaborocane analogues as inhibitors of AI-2 quorum sensing in Vibrio harveyi.

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2013: Martijn D P Risseeuw; Davy Sinnaeve; Jan Tavernier; Dries J H De Clercq; Ulrik Hillaert; Sam Lievens; José C Martins; Freya Van den Broeck; Serge Van Calenbergh
A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT.
ChemMedChem 2013;8(3):521-6.
2013: Višnja Popović; Serge Van Calenbergh; Arne Heyerick; Izet Karalić; Marjan Niketić; Silvana Petrović; Dieter Deforce
Sesquiterpene lactones from the extracts of two Balkan endemic Laserpitium species and their cytotoxic activity.
Phytochemistry 2013;87():102-11.
2013: Gilles Brackman; Abed Al Aziz Al Quntar; Claes D Enk; Izet Karalic; Hans J Nelis; Morris Srebnik; Serge Van Calenbergh; Tom Coenye
Synthesis and evaluation of thiazolidinedione and dioxazaborocane analogues as inhibitors of AI-2 quorum sensing in Vibrio harveyi.
Bioorganic & medicinal chemistry 2013;21(3):660-7.
2013: Thomas Verbrugghen; Johan Wouters; Louis Maes; Jenny Pouyez; Pierre Vandurm; Serge Van Calenbergh
Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials.
Journal of medicinal chemistry 2013;56(1):376-80.
2013: Kiran S Toti; Vladimir Frecer; Hélène Munier-Lehmann; Martijn D P Risseeuw; Frederick Verbeke; Serge Van Calenbergh
Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors.
Bioorganic & medicinal chemistry 2013;21(1):257-68.
2012: Gilles Brackman; Shari Celen; Paul Cos; Louis Maes; Hans J Nelis; Martijn Risseeuw; Serge Van Calenbergh; Tom Coenye
Synthesis and evaluation of the quorum sensing inhibitory effect of substituted triazolyldihydrofuranones.
Bioorganic & medicinal chemistry 2012;20(15):4737-43.
2012: Sara Van Poecke; Matthew O Barrett; Kenneth Alan Jacobson; T Kendall Harden; José C Martins; T Santhosh Kumar; Davy Sinnaeve; Serge Van Calenbergh
Synthesis and P2Y₂ receptor agonist activities of uridine 5'-phosphonate analogues.
Bioorganic & medicinal chemistry 2012;20(7):2304-15.
2012: Serge Van Calenbergh; Sylvie Pochet; Hélène Munier-Lehmann
Drug design and identification of potent leads against mycobacterium tuberculosis thymidine monophosphate kinase.
Current topics in medicinal chemistry 2012;12(7):694-705.
2012: Chaobo Huang; Joanna Rejman; Stefaan J Soenen; Marleen Temmerman; Serge Van Calenbergh; Ellen van Gulck; Guido Vanham; Hans Verstraelen; Chris Vervaet; Tom Coenye; Jo Demeester; Stefaan C De Smedt
Electrospun cellulose acetate phthalate fibers for semen induced anti-HIV vaginal drug delivery.
Biomaterials 2012;33(3):962-9.
2011: Nora Pauwels; Koen Sandra; Sandrine Aspeslagh; Dirk Elewaut; Bruno Linclau; Gerd Vanhoenacker; Esther D Yu; Dirk M Zajonc; Serge Van Calenbergh
Divergent synthetic approach to 6''-modified α-GalCer analogues.
Organic & biomolecular chemistry 2011;9(24):8413-21.
2011: Sara Van Poecke; Matheus Froeyen; Olivier Helynck; Hélène Munier-Lehmann; Serge Van Calenbergh
Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase.
Bioorganic & medicinal chemistry 2011;19(24):7603-11.
2011: Anne-Sophie Messiaen; Hans Nelis; Regina Ortmann; Martin Schlitzer; Serge Van Calenbergh; Thomas Verbrugghen; Charlotte Declerck; Tom Coenye
Resistance of the Burkholderia cepacia complex to fosmidomycin and fosmidomycin derivatives.
International journal of antimicrobial agents 2011;38(3):261-4.
2011: Kiran S Toti; Jan Balzarini; Marco Derudas; Christopher McGuigan; Serge Van Calenbergh
Synthesis and antiviral evaluation of α-L-2'-deoxythreofuranosyl nucleosides.
European journal of medicinal chemistry 2011;46(9):3704-13.
2011: Sandrine Aspeslagh; Yali Li; Esther Dawen Yu; Nora Pauwels; Matthias Trappeniers; Enrico Girardi; Tine Decruy; Katrien van Beneden; Koen Venken; Michael Drennan; Luc Leybaert; Jing Wang; Richard W Franck; Serge Van Calenbergh; Dirk M Zajonc; Dirk Elewaut
Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
The EMBO journal 2011;30(11):2294-305.
2011: Sara Van Poecke; Ana Negri; Jolien Janssens; Nicola Solaroli; Anna Karlsson; Federico Gago; Jan Balzarini; Serge Van Calenbergh
Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors.
Organic & biomolecular chemistry 2011;9(3):892-901.
2011: Gilles Brackman; Shari Celen; Ulrik Hillaert; Serge Van Calenbergh; Paul Cos; Louis Maes; Hans J Nelis; Tom Coenye
Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum sensing and their effect on virulence of Vibrio spp.
PloS one 2011;6(1):e16084.
2010: Radim Nencka; Davy Sinnaeve; Izet Karalic; José C Martins; Serge Van Calenbergh
Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki-Miyaura cross-coupling.
Organic & biomolecular chemistry 2010;8(22):5234-46.
2010: Katrien Forier; Anne-Sophie Messiaen; Tom Coenye; Hans Nelis; Shari Celen; Serge Van Calenbergh; Stefaan De Smedt; Jo Demeester; Kevin Braeckmans
Transport and delivery of antimicrobial agents in Burkholderia biofilms.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e35-6.
2010: Chaobo Huang; Bart Lucas; Chris Vervaet; Kevin Braeckmans; Serge Van Calenbergh; Izet Karalic; M Vandewoestyne; Dieter Deforce; Jo Demeester; Stefaan C De Smedt
Unbreakable codes in electrospun fibers to stop medicine counterfeiting.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e13-5.
2010: Laura Van Hoyweghen; Izet Karalic; Serge Van Calenbergh; Dieter Deforce; Arne Heyerick
Antioxidant flavone glycosides from the leaves of Fargesia robusta.
Journal of natural products 2010;73(9):1573-7.
2010: Thomas Verbrugghen; Paul Cos; Louis Maes; Serge Van Calenbergh
Synthesis and evaluation of alpha-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) as antimalarials.
Journal of medicinal chemistry 2010;53(14):5342-6.
2010: Chaobo Huang; Bart Lucas; Chris Vervaet; Kevin Braeckmans; Serge Van Calenbergh; Izet Karalic; Mado Vandewoestyne; Dieter Deforce; Jo Demeester; Stefaan C De Smedt
Unbreakable codes in electrospun fibers: digitally encoded polymers to stop medicine counterfeiting.
Advanced materials (Deerfield Beach, Fla.) 2010;22(24):2657-62.
2010: Sara Van Poecke; Ana Negri; Federico Gago; Ineke Van Daele; Nicola Solaroli; Anna Karlsson; Jan Balzarini; Serge Van Calenbergh
3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase.
Journal of medicinal chemistry 2010;53(7):2902-12.
2009: Gilles Brackman; Shari Celen; Kartik Baruah; Peter Bossier; Serge Van Calenbergh; Hans J Nelis; Tom Coenye
AI-2 quorum-sensing inhibitors affect the starvation response and reduce virulence in several Vibrio species, most likely by interfering with LuxPQ.
Microbiology (Reading, England) 2009;155(Pt 12):4114-22.
2009: Valerie Gossye; Dirk Elewaut; Nadia Bougarne; Debby Bracke; Serge Van Calenbergh; Guy Haegeman; Karolien De Bosscher
Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts.
Arthritis and rheumatism 2009;60(11):3241-50.
2009: Liesbet Cosyn; Serge Van Calenbergh; Bhalchandra V Joshi; Hyojin Ko; Rhonda L Carter; T Kendall Harden; Kenneth Alan Jacobson
Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives.
Bioorganic & medicinal chemistry letters 2009;19(11):3002-5.
2009: Leo Leung; Cyrille Tomassi; Katrien Van Beneden; Tine Decruy; Matthias Trappeniers; Dirk Elewaut; Yifang Gao; Tim Elliott; Aymen Al-Shamkhani; Christian Ottensmeier; Joern Werner; Anthony Williams; Serge Van Calenbergh; Bruno Linclau
The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000.
ChemMedChem 2009;4(3):329-34.
2008: Matthias Trappeniers; Katrien Van Beneden; Tine Decruy; Ulrik Hillaert; Bruno Linclau; Dirk Elewaut; Serge Van Calenbergh
6'-derivatised alpha-GalCer analogues capable of inducing strong CD1d-mediated Th1-biased NKT cell responses in mice.
Journal of the American Chemical Society 2008;130(49):16468-9.
2008: Leo Leung; Cyrille Tomassi; Katrien Van Beneden; Tine Decruy; Dirk Elewaut; Tim Elliott; Aymen Al-Shamkhani; Christian Ottensmeier; Serge Van Calenbergh; Joern Werner; Tony Williams; Bruno Linclau
Synthesis and in vivo evaluation of 4-deoxy-4,4-difluoro-KRN7000.
Organic letters 2008;10(20):4433-6.
2008: Matthias Trappeniers; Stijn Goormans; Katrien Van Beneden; Tine Decruy; Bruno Linclau; Aymen Al-Shamkhani; Tim Elliott; Christian Ottensmeier; Joern Werner; Dirk Elewaut; Serge Van Calenbergh
Synthesis and in vitro evaluation of alpha-GalCer epimers.
ChemMedChem 2008;3(7):1061-70.
2008: Hyojin Ko; Rhonda L Carter; Liesbet Cosyn; Riccardo Petrelli; Sonia De Castro; Pedro Besada; Yixing Zhou; Loredana Cappellacci; Palmarisa Franchetti; Mario Grifantini; Serge Van Calenbergh; T Kendall Harden; Kenneth Alan Jacobson
Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.
Bioorganic & medicinal chemistry 2008;16(12):6319-32.
2008: Dirk Giessmann; Philipp Heidler; Timothy Haemers; Serge Van Calenbergh; Armin Reichenberg; Hassan Jomaa; Claus Weidemeyer; Silke Sanderbrand; Jochen Wiesner; Andreas Link
Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
Chemistry & biodiversity 2008;5(4):643-56.
2008: Vadim Y Taraban; Sonya Martin; Kathrine E Attfield; Martin J Glennie; Tim Elliott; Dirk Elewaut; Serge Van Calenbergh; Bruno Linclau; Aymen Al-Shamkhani
Invariant NKT cells promote CD8+ cytotoxic T cell responses by inducing CD70 expression on dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4615-20.
2008: Ineke Van Daele; Niels Bomholt; Vyacheslav V Filichev; Serge Van Calenbergh; Erik B Pedersen
Triplex formation by pyrene-labelled probes for nucleic acid detection in fluorescence assays.
Chembiochem : a European journal of chemical biology 2008;9(5):791-801.
2008: Timothy Haemers; Jochen Wiesner; Dirk Giessmann; Thomas Verbrugghen; Ulrik Hillaert; Regina Ortmann; Hassan Jomaa; Andreas Link; Martin Schlitzer; Serge Van Calenbergh
Synthesis of beta- and gamma-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates.
Bioorganic & medicinal chemistry 2008;16(6):3361-71.
2008: pieter dewint; Valerie Gossye; Karolien De Bosscher; Wim Vanden Berghe; Katrien van Beneden; Dieter Deforce; Serge Van Calenbergh; Ulf Müller-Ladner; Bert Vander Cruyssen; Gust Verbruggen; Guy Haegeman; Dirk Elewaut
A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2608-15.
2007: Ineke Van Daele; Hélène Munier-Lehmann; Matheus Froeyen; Jan Balzarini; Serge Van Calenbergh
Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
Journal of medicinal chemistry 2007;50(22):5281-92.
2007: Vincent Devreux; Jochen Wiesner; Hassan Jomaa; Johan Van der Eycken; Serge Van Calenbergh
Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(17):4920-3.
2007: Ken Coppieters; Katrien van Beneden; Peggy Jacques; pieter dewint; Ann Vervloet; Bert Vander Cruyssen; Serge Van Calenbergh; Guangwu Chen; Richard W Franck; Gust Verbruggen; Dieter Deforce; Patrick Matthys; Moriya Tsuji; Pieter Rottiers; Dirk Elewaut
A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2300-9.
2007: Vincent Devreux; Jochen Wiesner; Hassan Jomaa; Jef Rozenski; Johan Van der Eycken; Serge Van Calenbergh
Divergent strategy for the synthesis of alpha-aryl-substituted fosmidomycin analogues.
The Journal of organic chemistry 2007;72(10):3783-9.
2006: Liesbet Cosyn; Krishnan K Palaniappan; Soo-Kyung Kim; Heng T Duong; Zhan-Guo Gao; Kenneth Alan Jacobson; Serge Van Calenbergh
2-triazole-substituted adenosines: a new class of selective A3 adenosine receptor agonists, partial agonists, and antagonists.
Journal of medicinal chemistry 2006;49(25):7373-83.
2006: Ineke Van Daele; Hélène Munier-Lehmann; Pieter M S Hendrickx; Gilles Marchal; Pierre Chavarot; Matheus Froeyen; Li Qing; José C Martins; Serge Van Calenbergh
Synthesis and biological evaluation of bicyclic nucleosides as inhibitors of M. tuberculosis thymidylate kinase.
ChemMedChem 2006;1(10):1081-90.
2006: Ulrik Hillaert; Swetlana Boldin-Adamsky; Jef Rozenski; Roger Busson; Anthony H Futerman; Serge Van Calenbergh
Synthesis and biological evaluation of novel PDMP analogues.
Bioorganic & medicinal chemistry 2006;14(15):5273-84.
2006: Zhan-Guo Gao; Heng T Duong; Lak Shin Jeong; Ae Yil Kim; Hea Ok Kim; Myong Jung Kim; Soo-Kyung Kim; Bruce T Liang; Liaman Mamedova; Tatiana Sonina; Serge Van Calenbergh; Philippe Van Rompaey; Kenneth Alan Jacobson
Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists.
Journal of medicinal chemistry 2006;49(9):2689-702.
2006: Vincent Devreux; Jochen Wiesner; Jan Goeman; Johan Van der Eycken; Hassan Jomaa; Serge Van Calenbergh
Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors.
Journal of medicinal chemistry 2006;49(8):2656-60.
2006: Timothy Haemers; Jochen Wiesner; Sara Van Poecke; Jan Goeman; Dajana Henschker; Ewald Beck; Hassan Jomaa; Serge Van Calenbergh
Synthesis of alpha-substituted fosmidomycin analogues as highly potent Plasmodium falciparum growth inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(7):1888-91.
2006: Liesbet Cosyn; Zhan-Guo Gao; Philippe Van Rompaey; Changrui Lu; Kenneth Alan Jacobson; Serge Van Calenbergh
Synthesis of hypermodified adenosine derivatives as selective adenosine A3 receptor ligands.
Bioorganic & medicinal chemistry 2006;14(5):1403-12.
2006: Serge Van Calenbergh
Structure-aided design of inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2006;68(4):223-48.
2005: Ulrik Hillaert; Serge Van Calenbergh
Synthesis of a versatile (S)-3-(hydroxymethyl)butane-1,2,4-triol building block and its application for the stereoselective synthesis of N-homoceramides.
Organic letters 2005;7(26):5769-72.
2005: Philippe Van Rompaey; Kenneth Alan Jacobson; Ariel S Gross; Zhan-Guo Gao; Serge Van Calenbergh
Exploring human adenosine A3 receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety.
Bioorganic & medicinal chemistry 2005;13(4):973-83.
2005: C Paepens; Sarah De Saeger; Christof Van Poucke; Fréderic Dumoulin; Serge Van Calenbergh; Carlos Van Peteghem
Development of a liquid chromatography/tandem mass spectrometry method for the quantification of fumonisin B1, B2 and B3 in cornflakes.
Rapid communications in mass spectrometry : RCM 2005;19(14):2021-9.
2004: Veerle Vanheusden; Hélène Munier-Lehmann; Matheus Froeyen; Roger Busson; Jef Rozenski; Piet Herdewijn; Serge Van Calenbergh
Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Journal of medicinal chemistry 2004;47(25):6187-94.
2004: Veerle Vanheusden; Roger Busson; Piet Herdewijn; Serge Van Calenbergh
Synthesis and conformational analysis of 1-[2,4-dideoxy-4-C-hydroxymethyl-alpha-l-lyxopyranosyl]thymine.
The Journal of organic chemistry 2004;69(13):4446-53.
2004: Michihiro Ohno; Zhan-Guo Gao; Philippe Van Rompaey; Susanna Tchilibon; Soo-Kyung Kim; Brian A Harris; Ariel S Gross; Heng T Duong; Serge Van Calenbergh; Kenneth Alan Jacobson
Modulation of adenosine receptor affinity and intrinsic efficacy in adenine nucleosides substituted at the 2-position.
Bioorganic & medicinal chemistry 2004;12(11):2995-3007.
2004: Katleen Baert; Siska Croubels; A Maes; Ulrik Hillaert; Serge Van Calenbergh; Patrick De Backer
Comparative metabolic excretion profile of sodium salicylate in broiler chickens and homing pigeons.
Journal of veterinary pharmacology and therapeutics 2004;27(2):123-7.
2004: Claudia Herforth; Jochen Wiesner; Philipp Heidler; Silke Sanderbrand; Serge Van Calenbergh; Hassan Jomaa; Andreas Link
Antimalarial activity of N(6)-substituted adenosine derivatives. Part 3.
Bioorganic & medicinal chemistry 2004;12(4):755-62.
2003: Soo-Kyung Kim; Zhan-Guo Gao; Philippe Van Rompaey; Ariel S Gross; Aishe Chen; Serge Van Calenbergh; Kenneth Alan Jacobson
Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists.
Journal of medicinal chemistry 2003;46(23):4847-59.
2003: Veerle Vanheusden; Philippe Van Rompaey; Hélène Munier-Lehmann; Sylvie Pochet; Piet Herdewijn; Serge Van Calenbergh
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Bioorganic & medicinal chemistry letters 2003;13(18):3045-8.
2003: Veerle Vanheusden; Hélène Munier-Lehmann; Matheus Froeyen; Laurence Dugué; Arne Heyerick; Denis De Keukeleire; Sylvie Pochet; Roger Busson; Piet Herdewijn; Serge Van Calenbergh
3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Journal of medicinal chemistry 2003;46(18):3811-21.
2003: Riet Dams; Els A De Letter; Kjell A Mortier; Jan A C M Cordonnier; Willy E Lambert; Michel H A Piette; Serge Van Calenbergh; André P De Leenheer
Fatality due to combined use of the designer drugs MDMA and PMA: a distribution study.
Journal of analytical toxicology 2003;27(5):318-22.
2003: Tommie L Lincecum; Michael Tukalo; Anna Yaremchuk; Richard S Mursinna; Amy M Williams; Brian S Sproat; Wendy Van Den Eynde; Andreas Link; Serge Van Calenbergh; Morten Grøtli; Susan A Martinis; Stephen Cusack
Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase.
Molecular cell 2003;11(4):951-63.
2003: Ahmed Haouz; Veerle Vanheusden; Hélène Munier-Lehmann; Matheus Froeyen; Piet Herdewijn; Serge Van Calenbergh; Marc Delarue
Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.
The Journal of biological chemistry 2003;278(7):4963-71.
2003: Ulrik Hillaert; Katleen Baert; Jef Rozenski; Siska Croubels; Denis De Keukeleire; Patrick De Backer; Serge Van Calenbergh
2,5-Bis-(2-hydroxybenzoylamino)pentanoic acid, a salicylic acid-metabolite isolated from chicken: characterization and independent synthesis.
Bioorganic & medicinal chemistry letters 2003;13(3):335-7.
2002: Veerle Vanheusden; Hélène Munier-Lehmann; Sylvie Pochet; Piet Herdewijn; Serge Van Calenbergh
Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Bioorganic & medicinal chemistry letters 2002;12(19):2695-8.
2002: Serge Van Calenbergh; Andreas Link; Shelly Fujikawa; Rianne A F de Ligt; Veerle Vanheusden; Abolfasl Golisade; Norbert Blaton; Jef Rozenski; Adriaan P IJzerman; Piet Herdewijn
5'-Deoxy congeners of 9-(3-amido-3-deoxy-beta-D-xylofuranosyl)-N(6)-cyclopentyladenine: new adenosine A(1) receptor antagonists and inverse agonists.
Journal of medicinal chemistry 2002;45(9):1845-52.
2002: Steven De Jonghe; Inge Lamote; Krishnan Venkataraman; Swetlana Boldin-Adamsky; Ulrik Hillaert; Jef Rozenski; Chris Hendrix; Roger Busson; Denis De Keukeleire; Serge Van Calenbergh; Anthony H Futerman; Piet Herdewijn
Synthesis of homoceramides, novel ceramide analogues, and their lack of effect on the growth of hippocampal neurons.
The Journal of organic chemistry 2002;67(3):988-96.
2002: Kjell A Mortier; Riet Dams; Willy E Lambert; Els A De Letter; Serge Van Calenbergh; André P De Leenheer
Determination of paramethoxyamphetamine and other amphetamine-related designer drugs by liquid chromatography/sonic spray ionization mass spectrometry.
Rapid communications in mass spectrometry : RCM 2002;16(9):865-70.
2001: Kenneth Alan Jacobson; Zhan-Guo Gao; Aishe Chen; Dov Barak; Soon-Ai Kim; Kyeong Lee; Andreas Link; P V Rompaey; Serge Van Calenbergh; Bruce T Liang
Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
Journal of medicinal chemistry 2001;44(24):4125-36.
2001: Danielle Borrey; Evelyne Meyer; Willy Lambert; Serge Van Calenbergh; Carlos Van Peteghem; André P De Leenheer
Sensitive gas chromatographic--mass spectrometric screening of acetylated benzodiazepines.
Journal of chromatography. A 2001;910(1):105-18.
2000: Karine M Clauwaert; Jan F Van Bocxlaer; Els A De Letter; Serge Van Calenbergh; Willy E Lambert; André P De Leenheer
Determination of the designer drugs 3, 4-methylenedioxymethamphetamine, 3,4-methylenedioxyethylamphetamine, and 3,4-methylenedioxyamphetamine with HPLC and fluorescence detection in whole blood, serum, vitreous humor, and urine.
Clinical chemistry 2000;46(12):1968-77.
2000: I Van Overmeire; Swetlana Boldin-Adamsky; Krishnan Venkataraman; Rivka Zisling; Steven De Jonghe; Serge Van Calenbergh; Denis De Keukeleire; Anthony H Futerman; Piet Herdewijn
Synthesis and biological evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety.
Journal of medicinal chemistry 2000;43(22):4189-99.
2000: Abolfasl Golisade; J C Bressi; Serge Van Calenbergh; M H Gelb; Andreas Link
Polymer-assisted solution-phase synthesis of 2'-amido-2'-deoxyadenosine derivatives targeted at the NAD(+)-binding sites of parasite enzymes.
Journal of combinatorial chemistry 2000;2(5):537-44.
1999: Steven De Jonghe; I Van Overmeire; S Poulton; Chris Hendrix; Roger Busson; Serge Van Calenbergh; Denis De Keukeleire; S Spiegel; Piet Herdewijn
Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase.
Bioorganic & medicinal chemistry letters 1999;9(21):3175-80.
1999: Steven De Jonghe; I Van Overmeire; J Gunst; A De Bruyn; Chris Hendrix; Serge Van Calenbergh; Roger Busson; Denis De Keukeleire; Jan Philippé; Piet Herdewijn
Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analogues.
Bioorganic & medicinal chemistry letters 1999;9(21):3159-64.
1999: Serge Van Calenbergh; Andreas Link; Conrad Kunick; Piet Herdewijn
Exploration of the effect of sterically demanding 3'-amido substitution of 3'-deoxyadenosines towards inhibition of cyclin-dependent kinase 1.
Die Pharmazie 1999;54(10):727-9.
1999: I Van Overmeire; Swetlana Boldin-Adamsky; F Dumont; Serge Van Calenbergh; G Slegers; Denis De Keukeleire; Anthony H Futerman; Piet Herdewijn
Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons.
Journal of medicinal chemistry 1999;42(14):2697-705.
1997: Serge Van Calenbergh; J K von Frijtag Drabbe Künzel; Norbert Blaton; Oswald M Peeters; Jef Rozenski; A Van Aerschot; A De Bruyn; Denis De Keukeleire; Adriaan P IJzerman; Piet Herdewijn
N6-cyclopentyl-3'-substituted-xylofuranosyladenosines: a new class of non-xanthine adenosine A1 receptor antagonists.
Journal of medicinal chemistry 1997;40(23):3765-72.
1995: Serge Van Calenbergh; Christophe Verlinde; J Soenens; A De Bruyn; Mia callens; Norbert Blaton; Oswald M Peeters; Jef Rozenski; Wim G J Hol; Piet Herdewijn
Synthesis and structure-activity relationships of analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine, a selective inhibitor of trypanosomal glycosomal glyceraldehyde-3-phosphate dehydrogenase.
Journal of medicinal chemistry 1995;38(19):3838-49.
1995: C Hendrix; M Mahieu; Jozef Anne; Serge Van Calenbergh; Arthur Van Aerschot; J Content; Piet Herdewijn
Catalytic activity and stability of hammerhead ribozymes containing 2'-acetamido-2'-deoxyribonucleosides.
Biochemical and biophysical research communications 1995;210(1):67-73.
1994: Christophe Verlinde; Mia callens; Serge Van Calenbergh; Arthur Van Aerschot; Piet Herdewijn; Véronique Hannaert; Paul A M Michels; Fred R Opperdoes; Wim G J Hol
Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based design: toward new drugs for the treatment of sleeping sickness.
Journal of medicinal chemistry 1994;37(21):3605-13.