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Peter van den Elsen

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Rutger J Wierda; Marja C J A van Eggermond; Jan C van Leeuwen; Anne Benard; Silvia Carluccio; Sacha Geutskens; J Wouter Jukema; Hedwich F Kuipers; Victor E Marquez; Paul H A Quax; Peter J van den Elsen
Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors.
Torsten B Meissner; Peter J van den Elsen; Marja C J A van Eggermond; Amlan Biswas; Kyoung-Hee Lee; Amy Li; Yuen-Joyce Liu; Koichi S Kobayashi
NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression.
Jack van Horssen; Maarten E Witte; Helga E de Vries; Wouter Gerritsen; Jeroen J G Geurts; Markus Kipp; Evert-Jan Kooi; Jamie L Lim; Laura Peferoen; Regina Peferoen-Baert; Shailender Singh; Peter J van den Elsen; Susanne M A van der Pol; Paul Van Der Valk; Sandra Amor
Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation.

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All Publications

2012: Rutger J Wierda; Marja C J A van Eggermond; Jan C van Leeuwen; Anne Benard; Silvia Carluccio; Sacha Geutskens; J Wouter Jukema; Hedwich F Kuipers; Victor E Marquez; Paul H A Quax; Peter J van den Elsen
Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors.
Journal of cellular and molecular medicine 2012;16(8):1866-77.
2012: Torsten B Meissner; Peter J van den Elsen; Marja C J A van Eggermond; Amlan Biswas; Kyoung-Hee Lee; Amy Li; Yuen-Joyce Liu; Koichi S Kobayashi
NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(10):4951-8.
2012: Jack van Horssen; Maarten E Witte; Helga E de Vries; Wouter Gerritsen; Jeroen J G Geurts; Markus Kipp; Evert-Jan Kooi; Jamie L Lim; Laura Peferoen; Regina Peferoen-Baert; Shailender Singh; Peter J van den Elsen; Susanne M A van der Pol; Paul Van Der Valk; Sandra Amor
Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation.
Journal of neuroinflammation 2012;9():156.
2011: Marja C J A van Eggermond; Rutger J Wierda; Daniël R Boom; Tjadine M Holling; Petra Klous; Victor E Marquez; Erik Schooten; Peter J van den Elsen
Epigenetic regulation of CIITA expression in human T-cells.
Biochemical pharmacology 2011;82(10):1430-7.
2011: Jessica C de Greef; Johan T den Dunnen; Laurence Duprez; Alina Ferster; Rune R Frants; Andrew R Gennery; Giorgio Gimelli; Arjan C Lankester; Ismail Reisli; Catharina Schuetz; Ansgar Schulz; Dominique F C M Smeets; Kirsten R Straasheijm; Yves Sznajer; Peter J van den Elsen; Mirjam van der Burg; Marja C J A van Eggermond; Monique M van Ostaijen-Ten Dam; Maarten J D van Tol; Jun Wang; Corry M Weemaes; Cisca Wijmenga; Caner Aytekin; Judit Balog; Silvère M van der Maarel
Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2.
American journal of human genetics 2011;88(6):796-804.
2011: Peter J van den Elsen; James McCluskey
Bringing antigens to attention: a conspiracy of genes, proteins and cells.
Current opinion in immunology 2011;23(1):78-80.
2011: Johannes M van Noort; Peter J van den Elsen; Jack van Horssen; Jeroen J G Geurts; Paul Van Der Valk; Sandra Amor
Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies.
CNS & neurological disorders drug targets 2011;10(1):68-81.
2011: Peter J van den Elsen
Expression regulation of major histocompatibility complex class I and class II encoding genes.
Frontiers in immunology 2011;2():48.
2011: Peter J van den Elsen; Marja C J A van Eggermond; Rutger J Wierda
Epigenetic control in immune function.
Advances in experimental medicine and biology 2011;711():36-49.
2011: Douwe Pons; Stella Trompet; Anton J M de Craen; Peter E Thijssen; Paul H A Quax; Margreet R De Vries; Rutger J Wierda; Peter J van den Elsen; Pascalle S Monraats; Mark M Ewing; Bas Heijmans; P Eline Slagboom; Aeilko H Zwinderman; Pieter A Doevendans; René A Tio; Robbert J De Winter; Moniek P M de Maat; Olga A Iakoubova; Naveed Sattar; Jim Shepherd; Rudi G J Westendorp; J Wouter Jukema
Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies.
Heart (British Cardiac Society) 2011;97(2):143-50.
2010: Esther M de Kruijf; Anita Sajet; Johanna G H van Nes; Russ Natanov; Hein Putter; Vincent T H B M Smit; GJ Liefers; Peter J van den Elsen; Cornelis J H van de Velde; Peter Kuppen
HLA-E and HLA-G expression in classical HLA class I-negative tumors is of prognostic value for clinical outcome of early breast cancer patients.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(12):7452-9.
2010: Seyma Charni; Geoffroy de Bettignies; Moeez G Rathore; Juan I Aguiló; Peter J van den Elsen; Delphine Haouzi; Robert A Hipskind; José Antonio Enriquez; Margarita Sanchez-Beato; Julián Pardo; Alberto Anel; Martin Villalba
Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(6):3498-503.
2010: Torsten B Meissner; Amy Li; Amlan Biswas; Kyoung-Hee Lee; Yuen-Joyce Liu; Erkan Bayir; Dimitrios Iliopoulos; Peter J van den Elsen; Koichi S Kobayashi
NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(31):13794-9.
2010: Rutger J Wierda; Sacha Geutskens; J Wouter Jukema; Paul H A Quax; Peter J van den Elsen
Epigenetics in atherosclerosis and inflammation.
Journal of cellular and molecular medicine 2010;14(6A):1225-40.
2010: Fanneke E Alkemade; Patrick van Vliet; Peter Henneman; Ko Willems van Dijk; Beerend P Hierck; J Conny van Munsteren; Joyce A Scheerman; Jelle J Goeman; Louis M Havekes; Adriana C Gittenberger-De Groot; Peter J van den Elsen; Marco C DeRuiter
Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature.
The American journal of pathology 2010;176(2):542-8.
2009: Tjadine M Holling; Marloes W T Bergevoet; Rutger J Wierda; Marja C J A van Eggermond; Peter J van den Elsen
Genetic and epigenetic control of the major histocompatibility complex class Ib gene HLA-G in trophoblast cell lines.
Annals of the New York Academy of Sciences 2009;1173():538-44.
2009: Dagmar Berghuis; Alfons S K de Hooge; Susy J Santos; Danielle Horst; Emmanuel J Wiertz; Marja C van Eggermond; Peter J van den Elsen; Antonie H M Taminiau; Laura Ottaviano; Karl-Ludwig Schaefer; Uta Dirksen; Erik Hooijberg; Arend Mulder; Cornelis J M Melief; R Maarten Egeler; Marco W Schilham; Ekaterina S. Jordanova; Pancras Hogendoorn; Arjan C Lankester
Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition.
The Journal of pathology 2009;218(2):222-31.
2009: Douwe Pons; Florentine R de Vries; Peter J van den Elsen; Bastiaan T Heijmans; Paul H A Quax; J Wouter Jukema
Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease.
European heart journal 2009;30(3):266-77.
2008: Hedwich F Kuipers; Paula J Biesta; Lisette J Montagne; Elise S van Haastert; Paul Van Der Valk; Peter J van den Elsen
CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factor.
Blood 2008;112(5):1610-9.
2008: Marja C J A van Eggermond; Ilhan Tezcan; Mirjam H M Heemskerk; Peter J van den Elsen
Transcriptional silencing of RFXAP in MHC class II-deficiency.
Molecular immunology 2008;45(10):2920-8.
2007: Tjadine M Holling; Marloes W T Bergevoet; Louis Wilson; Marja C J A van Eggermond; Erik Schooten; Renske D M Steenbergen; Peter J F Snijders; Martine J Jager; Peter J van den Elsen
A role for EZH2 in silencing of IFN-gamma inducible MHC2TA transcription in uveal melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5317-25.
2007: Hedwich F Kuipers; Peter J van den Elsen
Immunomodulation by statins: inhibition of cholesterol vs. isoprenoid biosynthesis.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2007;61(7):400-7.
2007: Nienke van der Stoep; Edwin Quinten; Gabrielle Alblas; Aurelie Plancke; Marja C J A van Eggermond; Tjadine M Holling; Peter J van den Elsen
Constitutive and IFNgamma-induced activation of MHC2TA promoter type III in human melanoma cell lines is governed by separate regulatory elements within the PIII upstream regulatory region.
Molecular immunology 2007;44(8):2036-46.
2006: Tjadine M Holling; Marja C J A van Eggermond; Martine J Jager; Peter J van den Elsen
Epigenetic silencing of MHC2TA transcription in cancer.
Biochemical pharmacology 2006;72(11):1570-6.
2006: Hedwich F Kuipers; Angelika A C Rappert; A Mieke Mommaas; Elise S van Haastert; Paul Van Der Valk; Hendrikus W G M Boddeke; Knut Biber; Peter J van den Elsen
Simvastatin affects cell motility and actin cytoskeleton distribution of microglia.
Glia 2006;53(2):115-23.
2005: Erik Schooten; Petra Klous; Peter J van den Elsen; Tjadine M Holling
Lack of MHC-II expression in activated mouse T cells correlates with DNA methylation at the CIITA-PIII region.
Immunogenetics 2005;57(10):795-9.
2005: Jeroen van Bergen; Charles Stewart; Peter J van den Elsen; John Trowsdale
Structural and functional differences between the promoters of independently expressed killer cell Ig-like receptors.
European journal of immunology 2005;35(7):2191-9.
2005: Ferry Ossendorp; Nathalie Fu; Marcel Camps; Francesca Granucci; Sam J P Gobin; Peter J van den Elsen; Danita Schuurhuis; Gosse J Adema; Grayson Lipford; Tomoki Chiba; Alice J A M Sijts; Peter-M Kloetzel; Paola Ricciardi-Castagnoli; Cornelis J M Melief
Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7815-22.
2005: Hedwich F Kuipers; Paula J Biesta; Tom A M Groothuis; Jacques Neefjes; A Mieke Mommaas; Peter J van den Elsen
Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains.
Human immunology 2005;66(6):653-65.
2005: Yvonne M Zoet; Chantal Eijsink; Marrie J Kardol; Marry E I Franke-van Dijk; G Louis Wilson; Roelof A de Paus; Eric Mickelson; Mirjam H M Heemskerk; Peter J van den Elsen; Frans H J Claas; Arend Mulder; Ilias Doxiadis
The single antigen expressing lines (SALs) concept: an excellent tool for screening for HLA-specific antibodies.
Human immunology 2005;66(5):519-25.
2005: Hedwich F Kuipers; Peter J van den Elsen
Statins and control of MHC2TA gene transcription.
Nature medicine 2005;11(4):365-6; author reply 366-7.
2005: Leonie C van Dinten; Nicolien Pul; A Frans van Nieuwpoort; Coby J Out; Martine J Jager; Peter J van den Elsen
Uveal and cutaneous melanoma: shared expression characteristics of melanoma-associated antigens.
Investigative ophthalmology & visual science 2005;46(1):24-30.
2004: Nienke van der Stoep; Edwin Quinten; Marisa Marcondes Rezende; Peter J van den Elsen
E47, IRF-4, and PU.1 synergize to induce B-cell-specific activation of the class II transactivator promoter III (CIITA-PIII).
Blood 2004;104(9):2849-57.
2004: Anita H Undale; Peter J van den Elsen; Esteban Celis
Antigen-independent acquisition of MHC class II molecules by human T lymphocytes.
International immunology 2004;16(10):1523-33.
2004: Tjadine M Holling; Nienke van der Stoep; Peter J van den Elsen
Epigenetic control of CIITA expression in leukemic T cells.
Biochemical pharmacology 2004;68(6):1209-13.
2004: Tjadine M Holling; Erik Schooten; Peter J van den Elsen
Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.
Human immunology 2004;65(4):282-90.
2004: Tjadine M Holling; Erik Schooten; Anton Langerak; Peter J van den Elsen
Regulation of MHC class II expression in human T-cell malignancies.
Blood 2004;103(4):1438-44.
2004: Peter J van den Elsen; Tjadine M Holling; Hedwich F Kuipers; Nienke van der Stoep
Transcriptional regulation of antigen presentation.
Current opinion in immunology 2004;16(1):67-75.
2003: Peter J van den Elsen; Tjadine M Holling; Nienke van der Stoep; Jeremy M Boss
DNA methylation and expression of major histocompatibility complex class I and class II transactivator genes in human developmental tumor cells and in T cell malignancies.
Clinical immunology (Orlando, Fla.) 2003;109(1):46-52.
2003: Sandra Hulshof; Elise S van Haastert; Hedwich F Kuipers; Peter J van den Elsen; Christianne J M De Groot; Paul Van Der Valk; Rivka Ravid; Knut Biber
CX3CL1 and CX3CR1 expression in human brain tissue: noninflammatory control versus multiple sclerosis.
Journal of neuropathology and experimental neurology 2003;62(9):899-907.
2003: Peter J van den Elsen; Nienke van der Stoep
Class II transactivator (CIITA) deficiency in tumor cells: complicated mechanisms or not?
The American journal of pathology 2003;163(1):373-5; author reply 375-6.
2003: Sam J P Gobin; Paula J Biesta; Peter J van den Elsen
Regulation of human beta 2-microglobulin transactivation in hematopoietic cells.
Blood 2003;101(8):3058-64.
2003: Gert Datema; Claudia A van Meir; Humphrey H H Kanhai; Peter J van den Elsen
Pre-term birth and severe pre-eclampsia are not associated with altered expression of HLA on human trophoblasts.
American journal of reproductive immunology (New York, N.Y. : 1989) 2003;49(4):193-201.
2002: Nienke van der Stoep; Edwin Quinten; Peter J van den Elsen
Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5'-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5061-71.
2002: Sam J P Gobin; Paula J Biesta; Jurriaan E M de Steenwinkel; Gert Datema; Peter J van den Elsen
HLA-G transactivation by cAMP-response element-binding protein (CREB). An alternative transactivation pathway to the conserved major histocompatibility complex (MHC) class I regulatory routes.
The Journal of biological chemistry 2002;277(42):39525-31.
2002: Nienke van der Stoep; Paula J Biesta; Edwin Quinten; Peter J van den Elsen
Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines.
International journal of cancer. Journal international du cancer 2002;97(4):501-7.
2002: Tjadine M Holling; Nienke van der Stoep; Edwin Quinten; Peter J van den Elsen
Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):763-70.
2001: H Monique H Hurks; M M Valter; L Wilson; I Hilgert; Peter J van den Elsen; Martine J Jager
Uveal melanoma: no expression of HLA-G.
Investigative ophthalmology & visual science 2001;42(13):3081-4.
2001: Sam J P Gobin; M van Zutphen; Sandy Westerheide; Jeremy M Boss; Peter J van den Elsen
The MHC-specific enhanceosome and its role in MHC class I and beta(2)-microglobulin gene transactivation.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5175-84.
2001: Peter J van den Elsen; Sam J P Gobin; Nienke van der Stoep; Gert Datema; HE Viëtor
Transcriptional control of MHC genes in fetal trophoblast cells.
Journal of reproductive immunology 2001;52(1-2):129-45.
2001: Sam J P Gobin; Lisette Montagne; M van Zutphen; Paul Van Der Valk; Peter J van den Elsen; Christianne J M De Groot
Upregulation of transcription factors controlling MHC expression in multiple sclerosis lesions.
Glia 2001;36(1):68-77.
2001: James T Kurnick; T Ramirez-Montagut; LA Boyle; David Andrews; Franco Pandolfi; Paul J Durda; David Butera; Ian S Dunn; Elizabeth M Benson; Sam J P Gobin; Peter J van den Elsen
A novel autocrine pathway of tumor escape from immune recognition: melanoma cell lines produce a soluble protein that diminishes expression of the gene encoding the melanocyte lineage melan-A/MART-1 antigen through down-modulation of its promoter.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1204-11.
2001: Jean-Pierre Bayley; H de Rooij; Peter J van den Elsen; Tom W J Huizinga; Cornelis L Verweij
Functional analysis of linker-scan mutants spanning the -376, -308, -244, and -238 polymorphic sites of the TNF-alpha promoter.
Cytokine 2001;14(6):316-23.
2001: Barbara C Godthelp; Maarten J D van Tol; Jaak M Vossen; Peter J van den Elsen
Longitudinal analysis of T cells responding to tetanus toxoid in healthy subjects as well as in pediatric patients after bone marrow transplantation: the identification of identical TCR-CDR3 regions in time suggests long-term stability of at least part of the antigen-specific TCR repertoire.
International immunology 2001;13(4):507-18.
2001: Sam J P Gobin; Peter J van den Elsen
Locus-specific regulation of HLA-A and HLA-B expression is not determined by nucleotide variation in the X2 box promoter element.
Blood 2001;97(5):1518-21.
2000: Sam J P Gobin; Peter J van den Elsen
Transcriptional regulation of the MHC class Ib genes HLA-E, HLA-F, and HLA-G.
Human immunology 2000;61(11):1102-7.
2000: Barbara C Godthelp; Marja C J A van Eggermond; Maarten J D van Tol; Jaak M Vossen; Peter J van den Elsen
T cell immune reconstitution after allogeneic bone marrow transplantation in bare lymphocyte syndrome.
Human immunology 2000;61(9):898-907.
2000: Peter J van den Elsen; Nienke van der Stoep; HE Viëtor; L Wilson; M van Zutphen; Sam J P Gobin
Lack of CIITA expression is central to the absence of antigen presentation functions of trophoblast cells and is caused by methylation of the IFN-gamma inducible promoter (PIV) of CIITA.
Human immunology 2000;61(9):850-62.
2000: Uma M Nagarajan; Ad Peijnenburg; Sam J P Gobin; Jeremy M Boss; Peter J van den Elsen
Novel mutations within the RFX-B gene and partial rescue of MHC and related genes through exogenous class II transactivator in RFX-B-deficient cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(7):3666-74.
2000: Ad Peijnenburg; RH van den Berg; M J Van Eggermond; Ozden Sanal; Jaak M Vossen; AM Lennon; Catherine Alcaïde-Loridan; Peter J van den Elsen
Defective MHC class II expression in an MHC class II deficiency patient is caused by a novel deletion of a splice donor site in the MHC class II transactivator gene.
Immunogenetics 2000;51(1):42-9.
2000: T Ramirez-Montagut; David Andrews; A Ihara; S Pervaiz; Franco Pandolfi; Peter J van den Elsen; R Waitkus; LA Boyle; M Hishii; James T Kurnick
Melanoma antigen recognition by tumour-infiltrating T lymphocytes (TIL): effect of differential expression of melan-A/MART-1.
Clinical and experimental immunology 2000;119(1):11-8.
1999: Barbara C Godthelp; Maarten J D van Tol; Jaak M Vossen; Peter J van den Elsen
T-Cell immune reconstitution in pediatric leukemia patients after allogeneic bone marrow transplantation with T-cell-depleted or unmanipulated grafts: evaluation of overall and antigen-specific T-cell repertoires.
Blood 1999;94(12):4358-69.
1999: Peter J van den Elsen; Sam J P Gobin
The common regulatory pathway of MHC class I and class II transactivation.
Microbes and infection / Institut Pasteur 1999;1(11):887-92.
1999: Sam J P Gobin; M van Zutphen; Andrea M Woltman; Peter J van den Elsen
Transactivation of classical and nonclassical HLA class I genes through the IFN-stimulated response element.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(3):1428-34.
1999: Ad Peijnenburg; M J Van Eggermond; Sam J P Gobin; RH van den Berg; Barbara C Godthelp; Jaak M Vossen; Peter J van den Elsen
Discoordinate expression of invariant chain and MHC class II genes in class II transactivator-transfected fibroblasts defective for RFX5.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):794-801.
1999: Barbara C Godthelp; Marja C J A van Eggermond; Ad Peijnenburg; Ilhan Tezcan; S van Lierde; Maarten J D van Tol; Jaak M Vossen; Peter J van den Elsen
Incomplete T-cell immune reconstitution in two major histocompatibility complex class II-deficiency/bare lymphocyte syndrome patients after HLA-identical sibling bone marrow transplantation.
Blood 1999;94(1):348-58.
1999: Sam J P Gobin; Vivian Keijsers; C Cheong; M van Zutphen; Peter J van den Elsen
Transcriptional regulation of HLA-G.
Transplantation proceedings 1999;31(4):1857-9.
1999: Gert Datema; Arend Mulder; Frans H J Claas; Peter J van den Elsen
Detection and characterization of HLA class I molecules in the supernatant of an hepatocarcinoma cell line and of EBV-transformed B cell lines.
Human immunology 1999;60(5):435-41.
1999: Ad Peijnenburg; Marja C J A van Eggermond; RH van den Berg; Ozden Sanal; Jaak M Vossen; Peter J van den Elsen
Molecular analysis of an MHC class II deficiency patient reveals a novel mutation in the RFX5 gene.
Immunogenetics 1999;49(4):338-45.
1999: Marieke Griffioen; IJ Ouwerkerk; V Harten; Sam J P Gobin; Peter J van den Elsen; Peter I Schrier
Role of the interferon-stimulated response element in HLA-B downregulation in human melanoma cell lines.
Immunogenetics 1999;49(4):287-94.
1999: Sam J P Gobin; Peter J van den Elsen
The regulation of HLA class I expression: is HLA-G the odd one out?
Seminars in cancer biology 1999;9(1):55-9.
1999: Barbara C Godthelp; Marja C J A van Eggermond; Sam J P Gobin; Peter J van den Elsen
Transcriptional control of MHC genes and T cell development in MHC class II deficiency.
Archivum immunologiae et therapiae experimentalis 1999;47(6):341-6.
1998: Sam J P Gobin; Ad Peijnenburg; Marja C J A van Eggermond; M van Zutphen; RH van den Berg; Peter J van den Elsen
The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes.
Immunity 1998;9(4):531-41.
1998: Sam J P Gobin; Vivian Keijsers; M van Zutphen; Peter J van den Elsen
The role of enhancer A in the locus-specific transactivation of classical and nonclassical HLA class I genes by nuclear factor kappa B.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2276-83.
1998: Peter J van den Elsen; Sam J P Gobin; Marja C J A van Eggermond; Ad Peijnenburg
Regulation of MHC class I and II gene transcription: differences and similarities.
Immunogenetics 1998;48(3):208-21.
1998: GE Hawes; L Struyk; H Beacock-Sharp; J Henwood; J S Hill Gaston; Peter J van den Elsen
Conserved TcR beta chain usage for a single MHC class II-restricted heat shock protein peptide.
Immunogenetics 1998;48(3):196-201.
1998: Peter J van den Elsen; Ad Peijnenburg; Marja C J A van Eggermond; Sam J P Gobin
Shared regulatory elements in the promoters of MHC class I and class II genes.
Immunology today 1998;19(7):308-12.
1998: Barbara C Godthelp; Maarten J D van Tol; Jaak M Vossen; Peter J van den Elsen
Long-term T cell immune reconstitution in 2 SCID patients after BMT.
Human immunology 1998;59(4):225-38.
1997: MJ Visseren; Sjoerd H van der burg; GE Hawes; Ellen I H van der Voort; Peter J van den Elsen; Cornelis J M Melief
Affinity, specificity and T-cell-receptor diversity of melanoma-specific CTL generated in vitro against a single tyrosinase epitope.
International journal of cancer. Journal international du cancer 1997;72(6):1122-8.
1997: HE Viëtor; GE Hawes; C van den Oever; E van Beelen; Humphrey H H Kanhai; Anneke Brand; Peter J van den Elsen
Intrauterine transfusions affect fetal T-cell immunity.
Blood 1997;90(6):2492-501.
1997: Ad Peijnenburg; Sam J P Gobin; Marja C J A van Eggermond; Barbara C Godthelp; N van Graafeiland; Peter J van den Elsen
Introduction of exogenous class II trans-activator in MHC class II-deficient ABI fibroblasts results in incomplete rescue of MHC class II antigen expression.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(6):2720-7.
1997: GE Hawes; HE Viëtor; H H Kanhai; Peter J van den Elsen
Skewing of TCR V genes to CD4+ and CD8+ subsets of T lymphocytes is not determined by amino acid composition of CDR3.
International immunology 1997;9(8):1103-10.
1997: Erliyani Sartono; Marja C J A van Eggermond; A Kurniawan; Rick M Maizels; Peter J van den Elsen; Maria Yazdanbakhsh
Selective usage of defined TCRBV genes in response to filarial antigens.
International immunology 1997;9(7):955-62.
1997: M Kumagai-Braesch; LA Boyle; Peter J van den Elsen; James T Kurnick
T cell receptor usage by HLA-DR3-specific T cell clones isolated from a renal allograft.
Transplant immunology 1997;5(2):129-35.
1997: Sam J P Gobin; Ad Peijnenburg; Vivian Keijsers; Peter J van den Elsen
Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA.
Immunity 1997;6(5):601-11.
1997: HE Viëtor; Jolande Elshove-Bolk; G R Vreugdenhil; Humphrey H H Kanhai; Peter J van den Elsen; Anneke Brand
Alterations in cord blood leukocyte subsets of patients with severe hemolytic disease after intrauterine transfusion therapy.
The Journal of pediatrics 1997;130(5):718-24.
1997: Barbara J van der Mast; HE Viëtor; E M van der Meer-Prins; Simone van Bree; Anneke Brand; Peter J van den Elsen; Frans H J Claas
Modulation of the T cell compartment by blood transfusion. Effect on cytotoxic and helper T lymphocyte precursor frequencies and T cell receptor Vbeta usage.
Transplantation 1997;63(8):1145-54.
1997: Sam J P Gobin; L Wilson; Vivian Keijsers; Peter J van den Elsen
Antigen processing and presentation by human trophoblast-derived cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3587-92.
1997: M Hishii; David Andrews; LA Boyle; J T Wong; Franco Pandolfi; Peter J van den Elsen; James T Kurnick
In vivo accumulation of the same anti-melanoma T cell clone in two different metastatic sites.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1378-83.
1996: L Struyk; GE Hawes; H M Mikkers; P P Tak; Ferdinand C Breedveld; Peter J van den Elsen
Molecular analysis of the T-cell receptor beta-chain repertoire in early rheumatoid arthritis: heterogeneous TCRBV gene usage with shared amino acid profiles in CDR3 regions of T lymphocytes in multiple synovial tissue needle biopsies from the same joint.
European journal of clinical investigation 1996;26(12):1092-102.
1996: M T Offermans; L Struyk; B de Geus; F C Breedveld; Peter J van den Elsen; Jan Rozing
Direct assessment of junctional diversity in rearranged T cell receptor beta chain encoding genes by combined heteroduplex and single strand conformation polymorphism (SSCP) analysis.
Journal of immunological methods 1996;191(1):21-31.
1996: J Henwood; Marja C J A van Eggermond; A H van Boxel-Dezaire; R Schipper; M den Hoedt; Ad Peijnenburg; O Sanal; F Ersoy; G T Rijkers; B J Zegers; Jaak M Vossen; Maarten J D van Tol; Peter J van den Elsen
Human T cell repertoire generation in the absence of MHC class II expression results in a circulating CD4+CD8- population with altered physicochemical properties of complementarity-determining region 3.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):895-906.
1995: L Struyk; GE Hawes; J B Haanen; René R P De Vries; Peter J van den Elsen
Clonal dominance and selection for similar complementarity determining region 3 motifs among T lymphocytes responding to the HLA-DR3-associated Mycobacterium leprae heat shock protein 65-kd peptide 3-13.
Human immunology 1995;44(4):220-7.
1995: L Struyk; GE Hawes; R J Dolhain; A van Scherpenzeel; Barbara C Godthelp; Ferdinand C Breedveld; Peter J van den Elsen
Evidence for selective in vivo expansion of synovial tissue-infiltrating CD4+CD45RO+ T-lymphocytes on the basis of CDR3 diversity.
Annals of the New York Academy of Sciences 1995;756():204-7.
1995: Els Goulmy; Jos Pool; Peter J van den Elsen
Interindividual conservation of T-cell receptor beta chain variable regions by minor histocompatibility antigen-specific HLA-A*0201-restricted cytotoxic T-cell clones.
Blood 1995;85(9):2478-81.
1995: F C Breedveld; L Struyk; J M van Laar; André M M Miltenburg; René R P De Vries; Peter J van den Elsen
Therapeutic regulation of T cells in rheumatoid arthritis.
Immunological reviews 1995;144():5-16.
1995: GE Hawes; L Struyk; Barbara C Godthelp; Peter J van den Elsen
Limited restriction in the TCR-alpha beta V region usage of antigen-specific clones. Recognition of myelin basic protein (amino acids 84-102) and Mycobacterium bovis 65-kDa heat shock protein (amino acids 3-13) by T cell clones established from peripheral blood mononuclear cells of monozygotic twins and HLA-identical individuals.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):555-66.
1995: L Struyk; GE Hawes; R J Dolhain; A van Scherpenzeel; Barbara C Godthelp; Ferdinand C Breedveld; Peter J van den Elsen
Evidence for selective usage of amino acids within CDR3 regions of T cell receptor V genes derived from synovial tissue-infiltrating CD4+CD45RO+ T-lymphocytes.
Scandinavian journal of rheumatology. Supplement 1995;101():147-52.
1995: Ad Peijnenburg; Barbara C Godthelp; A van Boxel-Dezaire; Peter J van den Elsen
Definition of a novel complementation group in MHC class II deficiency.
Immunogenetics 1995;41(5):287-94.
1994: T Mutis; Y E Cornelisse; G Datema; Peter J van den Elsen; Tom H M Ottenhoff; René R P De Vries
Definition of a human suppressor T-cell epitope.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9456-60.
1994: L Wilson; T Spies; Peter J van den Elsen
Cellular immune recognition of HLA-A*0201 following gene transfer into a human embryonal carcinoma cell line.
Human immunology 1994;41(1):74-8.
1994: L Struyk; GE Hawes; R J Dolhain; A van Scherpenzeel; Barbara C Godthelp; Ferdinand C Breedveld; Peter J van den Elsen
Evidence for selective in vivo expansion of synovial tissue-infiltrating CD4+ CD45RO+ T lymphocytes on the basis of CDR3 diversity.
International immunology 1994;6(6):897-907.
1994: G Datema; Leonard M B Vaessen; R C Daane; Carla C Baan; Willem Weimar; Frans H J Claas; Peter J van den Elsen
Functional and molecular characterization of graft-infiltrating T lymphocytes propagated from different biopsies derived from one heart transplant patient.
Transplantation 1994;57(7):1119-26.
1994: F M Raaphorst; Jeroen Van Bergen; R L van den Bergh; M van der Keur; R de Krijger; J Bruining; M J van Tol; Jaak M Vossen; Peter J van den Elsen
Usage of TCRAV and TCRBV gene families in human fetal and adult TCR rearrangements.
Immunogenetics 1994;39(5):343-50.
1994: F M Raaphorst; E L Kaijzel; M J van Tol; Jaak M Vossen; Peter J van den Elsen
Non-random employment of V beta 6 and J beta gene elements and conserved amino acid usage profiles in CDR3 regions of human fetal and adult TCR beta chain rearrangements.
International immunology 1994;6(1):1-9.
1993: Marja C J A van Eggermond; G T Rijkers; W Kuis; B J Zegers; Peter J van den Elsen
T cell development in a major histocompatibility complex class II-deficient patient.
European journal of immunology 1993;23(10):2585-91.
1993: GE Hawes; L Struyk; Peter J van den Elsen
Differential usage of T cell receptor V gene segments in CD4+ and CD8+ subsets of T lymphocytes in monozygotic twins.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(5):2033-45.
1993: G Datema; Leonard M B Vaessen; CR Daane; Carla C Baan; Willem Weimar; Frans H J Claas; Peter J van den Elsen
T-cell receptor V gene segment usage of graft-infiltrating T-lymphocytes after heart transplantation.
Transplantation proceedings 1993;25(1 Pt 1):77-9.
1992: J M van Laar; André M M Miltenburg; M J Verdonk; Mohamed R Daha; René R P De Vries; Peter J van den Elsen; Ferdinand C Breedveld
T-cell receptor beta-chain gene rearrangements of T-cell populations expanded from multiple sites of synovial tissue obtained from a patient with rheumatoid arthritis.
Scandinavian journal of immunology 1992;35(2):187-94.
1991: T F Rinke de Wit; L Wilson; Peter J van den Elsen; F Thielen; D Brekhoff; J W Oosterhuis; M F Pera; Peter L Stern
Monoclonal antibodies to human embryonal carcinoma cells: antigenic relationships of germ cell tumors.
Laboratory investigation; a journal of technical methods and pathology 1991;65(2):180-91.
1991: Tom H M Ottenhoff; J B Haanen; Annemieke Geluk; T Mutis; B K Ab; J E Thole; W C van Schooten; Peter J van den Elsen; René R P De Vries
Regulation of mycobacterial heat-shock protein-reactive T cells by HLA class II molecules: lessons from leprosy.
Immunological reviews 1991;121():171-91.
1991: J M Van Laar; André M M Miltenburg; M J Verdonk; Mohamed R Daha; René R P De Vries; Peter J van den Elsen; Ferdinand C Breedveld
Lack of T cell oligoclonality in enzyme-digested synovial tissue and in synovial fluid in most patients with rheumatoid arthritis.
Clinical and experimental immunology 1991;83(3):352-8.
1990: T F Rinke de Wit; S Vloemans; Peter J van den Elsen; A Haworth; Peter L Stern
Differential expression of the HLA class I multigene family by human embryonal carcinoma and choriocarcinoma cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(3):1080-7.
1990: M Lambert; Marja C J A van Eggermond; M E Kraakman; R K Schuurman; Peter J van den Elsen
The MHC class II deficiency syndrome: heterogeneity at the level of the response to 5-azadeoxycytidine.
Research in immunology 1990;141(2):129-40.
1990: André M M Miltenburg; J M van Laar; Mohamed R Daha; René R P De Vries; Peter J van den Elsen; Ferdinand C Breedveld
Dominant T-cell receptor beta-chain gene rearrangements indicate clonal expansion in the rheumatoid joint.
Scandinavian journal of immunology 1990;31(1):121-6.
1990: T F Rinke de Wit; L Struyk; S Vloemans; J Glazebrook; J M Boyle; Peter L Stern; Peter J van den Elsen
HLA class I homologous transcripts in the human embryonal carcinoma cell line Tera-2.
Immunogenetics 1990;32(3):187-94.
1989: T F Rinke de Wit; A A Vloemans; Peter J van den Elsen; J Ward; R C Sutcliffe; J Glazebrook; A Haworth; Peter L Stern
Novel human MHC class I genes are expressed by tumour cell lines representing embryonic and extraembryonic tissues.
Journal of immunogenetics 1989;16(4-5):391-6.