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Chris Van den Haute

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Werend Boesmans; C Cirillo; Inge Depoortere; Jan Tack; V Van den Abbeel; Chris Van den Haute; Pieter Vanden Berghe
Neurotransmitters involved in fast excitatory neurotransmission directly activate enteric glial cells.
Mustafa Varcin; Chris Van den Haute; Veerle Baekelandt; Eduard Bentea; Birgit Mertens; Yvette Michotte; Sophie Sarre
Acute versus long-term effects of 6-hydroxydopamine on oxidative stress and dopamine depletion in the striatum of mice.
A Van der Perren; Jaan Toelen; M Carlon; Chris Van den Haute; F Coun; B Heeman; V Reumers; Luk Vandenberghe; James M Wilson; zeger debyser; Veerle Baekelandt
Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9.

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All Publications

2013: Werend Boesmans; C Cirillo; Inge Depoortere; Jan Tack; V Van den Abbeel; Chris Van den Haute; Pieter Vanden Berghe
Neurotransmitters involved in fast excitatory neurotransmission directly activate enteric glial cells.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2013;25(2):e151-60.
2011: Mustafa Varcin; Chris Van den Haute; Veerle Baekelandt; Eduard Bentea; Birgit Mertens; Yvette Michotte; Sophie Sarre
Acute versus long-term effects of 6-hydroxydopamine on oxidative stress and dopamine depletion in the striatum of mice.
Journal of neuroscience methods 2011;202(2):128-36.
2011: A Van der Perren; Jaan Toelen; M Carlon; Chris Van den Haute; F Coun; B Heeman; V Reumers; Luk Vandenberghe; James M Wilson; zeger debyser; Veerle Baekelandt
Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9.
Gene therapy 2011;18(5):517-27.
2011: Bavo Heeman; Chris Van den Haute; Sarah-Ann Aelvoet; Federica Valsecchi; Richard J Rodenburg; Veerle Reumers; zeger debyser; Geert Callewaert; Werner J H Koopman; Peter H G M Willems; Veerle Baekelandt
Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance.
Journal of cell science 2011;124(Pt 7):1115-25.
2010: Helena Slaets; Jerome J A Hendriks; Chris Van den Haute; Frea Coun; Veerle Baekelandt; Piet Stinissen; Niels Hellings
CNS-targeted LIF expression improves therapeutic efficacy and limits autoimmune-mediated demyelination in a model of multiple sclerosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(4):684-91.
2010: Melanie Gerard; Angélique Deleersnijder; Veronique Daniëls; Sarah Schreurs; Sebastian Munck; Veerle Reumers; Hans Pottel; Yves Engelborghs; Chris Van den Haute; Jean-Marc Taymans; zeger debyser; Veerle Baekelandt
Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(7):2454-63.
2010: Fabienne C Fiesel; Aaron Voigt; Stephanie S Weber; Chris Van den Haute; Andrea Waldenmaier; Karin Görner; Michael Walter; Marlene L Anderson; Jeannine V Kern; Tobias Rasse; Thorsten Schmidt; Wolfdieter Springer; Roland Kirchner; Michael Bonin; Manuela Neumann; Veerle Baekelandt; Marianna Alunni-Fabbroni; Jörg B Schulz; Philipp J Kahle
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6.
The EMBO journal 2010;29(1):209-21.
2010: Evy Lobbestael; Veerle Reumers; Abdelilah Ibrahimi; Kirsten Paesen; Irina Thiry; Rik Gijsbers; Chris Van den Haute; zeger debyser; Veerle Baekelandt; Jean-Marc Taymans
Immunohistochemical detection of transgene expression in the brain using small epitope tags.
BMC biotechnology 2010;10():16.
2008: Veerle Reumers; Christophe M Deroose; Olga Krylyshkina; Johan Nuyts; Martine Geraerts; Luc Mortelmans; Rik Gijsbers; Chris Van den Haute; zeger debyser; Veerle Baekelandt
Noninvasive and quantitative monitoring of adult neuronal stem cell migration in mouse brain using bioluminescence imaging.
Stem cells (Dayton, Ohio) 2008;26(9):2382-90.
2006: Linda Vercammen; Anke Van der Perren; Elisabetta Vaudano; Rik Gijsbers; zeger debyser; Chris Van den Haute; Veerle Baekelandt
Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(5):716-23.
2006: Jean-Marc Taymans; Chris Van den Haute; Veerle Baekelandt
Distribution of PINK1 and LRRK2 in rat and mouse brain.
Journal of neurochemistry 2006;98(3):951-61.
2006: Linos Vandekerckhove; Frauke Christ; Bénédicte Van Maele; Jan De Rijck; Rik Gijsbers; Chris Van den Haute; Myriam Witvrouw; zeger debyser
Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus.
Journal of virology 2006;80(4):1886-96.
2003: Chris Van den Haute; Kristel Eggermont; Bart Nuttin; zeger debyser; Veerle Baekelandt
Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain.
Human gene therapy 2003;14(18):1799-807.
2003: Jo Van Dorpe; Kurt Spittaels; Chris Van den Haute; Ilse Dewachter; Dieder Moechars; Hugo Geerts; Fred Van Leuven
Neuropathobiology in transgenic mice. The case of Alzheimer's disease.
Methods in molecular biology (Clifton, N.J.) 2003;209():333-61.
2002: Kelly Tilleman; Chris Van den Haute; Hugo Geerts; Fred Van Leuven; Eddy L Esmans; Luc Moens
Proteomics analysis of the neurodegeneration in the brain of tau transgenic mice.
Proteomics 2002;2(6):656-65.
2002: Ilse Dewachter; Delphine Reversé; Nathalie Caluwaerts; Laurence Ris; Cuno Kuipéri; Chris Van den Haute; Kurt Spittaels; Lieve Umans; Lutgarde Serneels; Els Thiry; Dieder Moechars; Marc Mercken; Emile Godaux; Fred Van Leuven
Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(9):3445-53.
2002: Rony Nuydens; G van den Kieboom; C Nolten; C Verhulst; Peter Van Osta; Kurt Spittaels; Chris Van den Haute; E De Feyter; Hugo Geerts; Fred Van Leuven
Coexpression of GSK-3beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau.
Neurobiology of disease 2002;9(1):38-48.
2002: Kurt Spittaels; Chris Van den Haute; Jo Van Dorpe; Dick Terwel; K Vandezande; Reena Lasrado; K Bruynseels; Michael C Irizarry; Marleen Verhoye; Johan Van Lint; Jackie R Vandenheede; D Ashton; Marc Mercken; R Loos; Bradley T Hyman; Annemie Van der Linden; Hugo Geerts; Fred Van Leuven
Neonatal neuronal overexpression of glycogen synthase kinase-3 beta reduces brain size in transgenic mice.
Neuroscience 2002;113(4):797-808.
2001: Chris Van den Haute; Kurt Spittaels; Jo Van Dorpe; Reena Lasrado; K Vandezande; I Laenen; Hugo Geerts; Fred Van Leuven
Coexpression of human cdk5 and its activator p35 with human protein tau in neurons in brain of triple transgenic mice.
Neurobiology of disease 2001;8(1):32-44.
2001: Ilse Dewachter; Dieder Moechars; Jo Van Dorpe; Ina C. Tesseur; Chris Van den Haute; Kurt Spittaels; Fred Van Leuven
Modelling Alzheimer's disease in multiple transgenic mice.
Biochemical Society symposium 2001;(67):203-10.
2000: Kurt Spittaels; Chris Van den Haute; Jo Van Dorpe; Hugo Geerts; Marc Mercken; K Bruynseels; Reena Lasrado; K Vandezande; I Laenen; T Boon; Johan Van Lint; Jackie R Vandenheede; Dieder Moechars; R Loos; Fred Van Leuven
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.
The Journal of biological chemistry 2000;275(52):41340-9.
2000: Jo Van Dorpe; Liesbet Smeijers; Ilse Dewachter; Dieter Nuyens; Kurt Spittaels; Chris Van den Haute; Marc Mercken; Dieder Moechars; I Laenen; Cuno Kuiperi; K Bruynseels; Ina C. Tesseur; R Loos; hugo vanderstichele; F Checler; Raf Sciot; Fred Van Leuven
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
The American journal of pathology 2000;157(4):1283-98.
2000: Ilse Dewachter; Jo Van Dorpe; Kurt Spittaels; Ina C. Tesseur; Chris Van den Haute; Dieder Moechars; Fred Van Leuven
Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.
Experimental gerontology 2000;35(6-7):831-41.
2000: Ina C. Tesseur; Jo Van Dorpe; Kurt Spittaels; Chris Van den Haute; Dieder Moechars; Fred Van Leuven
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice.
The American journal of pathology 2000;156(3):951-64.
1999: Kurt Spittaels; Chris Van den Haute; Jo Van Dorpe; K Bruynseels; K Vandezande; I Laenen; Hugo Geerts; Marc Mercken; Raf Sciot; Alfons Van Lommel; R Loos; Fred Van Leuven
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein.
The American journal of pathology 1999;155(6):2153-65.