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Guy Van den Mooter
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39
Augustijns, Patrick
37
Kinget, Renaat
13
Peeters, Jef
13
Blaton, Norbert
13
Brewster, Marcus
13
Verreck, Geert
12
Naesens, Lieve
12
Martens, Johan
10
De Clercq, Erik
10
Annaert, Pieter
9
Remon, Jean Paul
8
Van Gelder, Jan
7
Vervaet, Chris
7
Samyn, C
7
Six, Karel
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All Publications
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2009: François Isabelle E J A; Bink Anna; Vandercappellen Jo; Ayscough Kathryn R; Toulmay Alexandre; Schneiter Roger; van Gyseghem Elke; Van den Mooter Guy; Borgers Marcel; Vandenbosch Davy; Coenye Tom; Cammue Bruno P A; Thevissen Karin
Membrane rafts are involved in intracellular miconazole accumulation in yeast cells.
The Journal of biological chemistry 2009;284(47):32680-5.
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2009: Van Eerdenbrugh Bernard; Van Speybroeck Michiel; Mols Raf; Houthoofd Kristof; Martens Johan A; Froyen Ludo; Van Humbeeck Jan; Augustijns Patrick; Van den Mooter Guy
Itraconazole/TPGS/Aerosil200 solid dispersions: characterization, physical stability and in vivo performance.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;38(3):270-8.
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2009: Verhoeven E; Siepmann F; De Beer T R M; Van Loo D; Van den Mooter G; Remon J P; Siepmann J; Vervaet C
Modeling drug release from hot-melt extruded mini-matrices with constant and non-constant diffusivities.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;73(2):292-301.
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2009: Van Speybroeck Michiel; Barillaro Valéry; Thi Thao Do; Mellaerts Randy; Martens Johan; Van Humbeeck Jan; Vermant Jan; Annaert Pieter; Van den Mooter Guy; Augustijns Patrick
Ordered mesoporous silica material SBA-15: a broad-spectrum formulation platform for poorly soluble drugs.
Journal of pharmaceutical sciences 2009;98(8):2648-58.
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2009: Janssens Sandrien; Anné Michael; Rombaut Patrick; Van den Mooter Guy
Spray drying from complex solvent systems broadens the applicability of Kollicoat IR as a carrier in the formulation of solid dispersions.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;37(3-4):241-8.
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2009: Verhoeven E; De Beer T R M; Schacht E; Van den Mooter G; Remon J P; Vervaet C
Influence of polyethylene glycol/polyethylene oxide on the release characteristics of sustained-release ethylcellulose mini-matrices produced by hot-melt extrusion: in vitro and in vivo evaluations.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;72(2):463-70.
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2009: Van Eerdenbrugh Bernard; Vermant Jan; Martens Johan A; Froyen Ludo; Van Humbeeck Jan; Augustijns Patrick; Van den Mooter Guy
A screening study of surface stabilization during the production of drug nanocrystals.
Journal of pharmaceutical sciences 2009;98(6):2091-103.
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2009: de Armas Héctor Novoa; Peeters Oswald M; Blaton Norbert; Van Gyseghem Elke; Martens Johan; Van Haele Gerrit; Van Den Mooter Guy
Solid state characterization and crystal structure from X-ray powder diffraction of two polymorphic forms of ranitidine base.
Journal of pharmaceutical sciences 2009;98(1):146-58.
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2009: Van Eerdenbrugh Bernard; Stuyven Bernard; Froyen Ludo; Van Humbeeck Jan; Martens Johan A; Augustijns Patrick; Van den Mooter Guy
Downscaling drug nanosuspension production: processing aspects and physicochemical characterization.
AAPS PharmSciTech 2009;10(1):44-53.
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2008: Van Eerdenbrugh Bernard; Van den Mooter Guy; Augustijns Patrick
Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products.
International journal of pharmaceutics 2008;364(1):64-75.
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2008: Goddeeris C; Willems T; Houthoofd K; Martens J A; Van den Mooter G
Dissolution enhancement of the anti-HIV drug UC 781 by formulation in a ternary solid dispersion with TPGS 1000 and Eudragit E100.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(3):861-8.
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2008: Van Gyseghem Elke; Pendela Murali; Baert Lieven; Rosier Jan; Van 't Klooster Gerben; De Man Hilde; Bouche Marie-Paule; Schueller Laurent; Van Remoortere Pieter; Wigerinck Piet; Adams Erwin; Hoogmartens Jos; Van den Mooter Guy
Powder for reconstitution of the anti-HIV-1 drug TMC278 - Formulation development, stability and animal studies.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(3):853-60.
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2008: Janssens Sandrien; Denivelle Samgar; Rombaut Patrick; Van den Mooter Guy
Influence of polyethylene glycol chain length on compatibility and release characteristics of ternary solid dispersions of itraconazole in polyethylene glycol/hydroxypropylmethylcellulose 2910 E5 blends.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;35(3):203-10.
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2008: Van Eerdenbrugh Bernard; Vercruysse Sofie; Martens Johan A; Vermant Jan; Froyen Ludo; Van Humbeeck Jan; Van den Mooter Guy; Augustijns Patrick
Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions - a case study with itraconazole.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(2):590-6.
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2008: Janssens Sandrien; Humbeeck Jan Van; Van den Mooter Guy
Evaluation of the formulation of solid dispersions by co-spray drying itraconazole with Inutec SP1, a polymeric surfactant, in combination with PVPVA 64.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(2):500-5.
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2008: Goddeeris Caroline; Van den Mooter Guy
Free flowing solid dispersions of the anti-HIV drug UC 781 with Poloxamer 407 and a maximum amount of TPGS 1000: investigating the relationship between physicochemical characteristics and dissolution behaviour.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;35(1-2):104-13.
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2008: Van Eerdenbrugh Bernard; Froyen Ludo; Van Humbeeck Jan; Martens Johan A; Augustijns Patrick; Van den Mooter Guy
Drying of crystalline drug nanosuspensions-the importance of surface hydrophobicity on dissolution behavior upon redispersion.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;35(1-2):127-35.
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2008: Barillaro Valéry; Pescarmona Paolo P; Van Speybroeck Michiel; Thi Thao Do; Van Humbeeck Jan; Vermant Jan; Augustijns Patrick; Martens Johan A; Van Den Mooter Guy
High-throughput study of phenytoin solid dispersions: formulation using an automated solvent casting method, dissolution testing, and scaling-up.
Journal of combinatorial chemistry 2008;10(5):637-43.
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2008: Mellaerts Randy; Jammaer Jasper A G; Van Speybroeck Michiel; Chen Hong; Van Humbeeck Jan; Augustijns Patrick; Van den Mooter Guy; Martens Johan A
Physical state of poorly water soluble therapeutic molecules loaded into SBA-15 ordered mesoporous silica carriers: a case study with itraconazole and ibuprofen.
Langmuir : the ACS journal of surfaces and colloids 2008;24(16):8651-9.
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2008: Goddeeris Caroline; Willems Tom; Van den Mooter Guy
Formulation of fast disintegrating tablets of ternary solid dispersions consisting of TPGS 1000 and HPMC 2910 or PVPVA 64 to improve the dissolution of the anti-HIV drug UC 781.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;34(4-5):293-302.
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2008: Janssens Sandrien; de Armas Hector Novoa; D'Autry Ward; Van Schepdael Ann; Van den Mooter Guy
Characterization of ternary solid dispersions of Itraconazole in polyethylene glycol 6000/polyvidone-vinylacetate 64 blends.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(3):1114-20.
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2008: Mellaerts Randy; Mols Raf; Kayaert Pieterjan; Annaert Pieter; Van Humbeeck Jan; Van den Mooter Guy; Martens Johan A; Augustijns Patrick
Ordered mesoporous silica induces pH-independent supersaturation of the basic low solubility compound itraconazole resulting in enhanced transepithelial transport.
International journal of pharmaceutics 2008;357(1-2):169-79.
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2008: Janssens Sandrien; de Armas Hector Novoa; Roberts Clive J; Van den Mooter Guy
Characterization of ternary solid dispersions of itraconazole, PEG 6000, and HPMC 2910 E5.
Journal of pharmaceutical sciences 2008;97(6):2110-20.
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2008: Baert Lieven; Schueller Laurent; Tardy Yanik; Macbride Doug; Klooster Gerben van't; Borghys Herman; Clessens Ellen; Van Den Mooter Guy; Van Gyseghem Elke; Van Remoortere Pieter; Wigerinck Piet; Rosier Jan
Development of an implantable infusion pump for sustained anti-HIV drug administration.
International journal of pharmaceutics 2008;355(1-2):38-44.
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2008: Janssens Sandrien; Roberts Clive; Smith Emily F; Van den Mooter Guy
Physical stability of ternary solid dispersions of itraconazole in polyethyleneglycol 6000/hydroxypropylmethylcellulose 2910 E5 blends.
International journal of pharmaceutics 2008;355(1-2):100-7.
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2008: Mellaerts Randy; Mols Raf; Jammaer Jasper A G; Aerts Caroline A; Annaert Pieter; Van Humbeeck Jan; Van den Mooter Guy; Augustijns Patrick; Martens Johan A
Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(1):223-30.
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2008: Janssens Sandrien; Nagels Sophie; Armas Hector Novoa de; D'Autry Ward; Van Schepdael Ann; Van den Mooter Guy
Formulation and characterization of ternary solid dispersions made up of Itraconazole and two excipients, TPGS 1000 and PVPVA 64, that were selected based on a supersaturation screening study.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(1):158-66.
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2008: Schueller Laurent; Baert Lieven; Lachau-Durand Sophie; Borghys Herman; Clessens Ellen; Van Den Mooter Guy; Van Gyseghem Elke; Jonckers Tim H M; Van Remoortere Pieter; Wigerinck Piet; Rosier Jan
Dog model with implanted pump to test boosters for antiretroviral medication.
International journal of pharmaceutics 2008;355(1-2):45-52.
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2008: Verhoeven E; De Beer T R M; Van den Mooter G; Remon J P; Vervaet C
Influence of formulation and process parameters on the release characteristics of ethylcellulose sustained-release mini-matrices produced by hot-melt extrusion.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(1):312-9.
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2007: Wang Xin; de Armas Hector Novoa; Blaton Norbert; Michoel Armand; Van den Mooter Guy
Phase characterization of indomethacin in binary solid dispersions with PVP VA64 or Myrj 52.
International journal of pharmaceutics 2007;345(1-2):95-100.
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2007: Ye Zhi-wei; Rombout Patrick; Remon Jean Paul; Vervaet Chris; Van den Mooter Guy
Correlation between the permeability of metoprolol tartrate through plasticized isolated ethylcellulose/hydroxypropyl methylcellulose films and drug release from reservoir pellets.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;67(2):485-90.
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2007: Van Eerdenbrugh B; Froyen L; Martens J A; Blaton N; Augustijns P; Brewster M; Van den Mooter G
Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling.
International journal of pharmaceutics 2007;338(1-2):198-206.
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2007: de Armas Héctor Novoa; Peeters Oswald M; Van den Mooter Guy; Blaton Norbert
Polymorphism of Alprazolam (Xanax): a review of its crystalline phases and identification, crystallographic characterization, and crystal structure of a new polymorph (form III).
Journal of pharmaceutical sciences 2007;96(5):1114-30.
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2007: Goddeeris C; Coacci J; Van den Mooter G
Correlation between digestion of the lipid phase of smedds and release of the anti-HIV drug UC 781 and the anti-mycotic drug enilconazole from smedds.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;66(2):173-81.
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2007: Van Herrewege Yven; Michiels Jo; Waeytens Anouk; De Boeck Gitte; Salden Evelyne; Heyndrickx Leo; van den Mooter Guy; de Béthune Marie-Pierre; Andries Koen; Lewi Paul; Praet Marleen; Vanham Guido
A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides.
Antiviral research 2007;74(2):111-24.
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2007: Mellaerts Randy; Aerts Caroline A; Van Humbeeck Jan; Augustijns Patrick; Van den Mooter Guy; Martens Johan A
Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials.
Chemical communications (Cambridge, England) 2007;(13):1375-7.
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2007: Janssens Sandrien; de Armas Hector Novoa; Remon Jean Paul; Van den Mooter Guy
The use of a new hydrophilic polymer, Kollicoat IR, in the formulation of solid dispersions of Itraconazole.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(3-4):288-94.
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2006: Verreck Geert; Decorte Annelies; Heymans Koen; Adriaensen Jef; Liu Dehua; Tomasko David; Arien Albertina; Peeters Jef; Van den Mooter Guy; Brewster Marcus E
Hot stage extrusion of p-amino salicylic acid with EC using CO2 as a temporary plasticizer.
International journal of pharmaceutics 2006;327(1-2):45-50.
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2006: de Armas Héctor Novoa; Peeters Oswald M; Blaton Norbert; Van den Mooter Guy; De Ridder Dirk J A; Schenk Henk
Crystal structure of carnidazole form II from synchrotron X-ray powder diffraction: structural comparison with form I, the hydrated form and the low energy conformations in vacuo.
Journal of pharmaceutical sciences 2006;95(10):2123-36.
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2006: Van den Mooter Guy; Weuts Ilse; De Ridder Thomas; Blaton Norbert
Evaluation of Inutec SP1 as a new carrier in the formulation of solid dispersions for poorly soluble drugs.
International journal of pharmaceutics 2006;316(1-2):1-6.
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2006: Dillen Kathleen; Vandervoort Jo; Van den Mooter Guy; Ludwig Annick
Evaluation of ciprofloxacin-loaded Eudragit RS100 or RL100/PLGA nanoparticles.
International journal of pharmaceutics 2006;314(1):72-82.
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2006: Goddeeris C; Cuppo F; Reynaers H; Bouwman W G; Van den Mooter G
Light scattering measurements on microemulsions: estimation of droplet sizes.
International journal of pharmaceutics 2006;312(1-2):187-95.
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2006: Van den Mooter Guy
Colon drug delivery.
Expert opinion on drug delivery 2006;3(1):111-25.
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2005: Verreck Geert; Decorte Annelies; Heymans Koen; Adriaensen Jef; Cleeren Dirk; Jacobs Adri; Liu Dehua; Tomasko David; Arien Albertina; Peeters Jef; Rombaut Patrick; Van den Mooter Guy; Brewster Marcus E
The effect of pressurized carbon dioxide as a temporary plasticizer and foaming agent on the hot stage extrusion process and extrudate properties of solid dispersions of itraconazole with PVP-VA 64.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;26(3-4):349-58.
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2005: Wang Xin; Michoel Armand; Van den Mooter Guy
Solid state characteristics of ternary solid dispersions composed of PVP VA64, Myrj 52 and itraconazole.
International journal of pharmaceutics 2005;303(1-2):54-61.
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2005: Weuts Ilse; Kempen Dieter; Verreck Geert; Peeters Jef; Brewster Marcus; Blaton Norbert; Van den Mooter Guy
Salt formation in solid dispersions consisting of polyacrylic acid as a carrier and three basic model compounds resulting in very high glass transition temperatures and constant dissolution properties upon storage.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;25(4-5):387-93.
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2005: Weuts Ilse; Kempen Dieter; Decorte Annelies; Verreck Geert; Peeters Jef; Brewster Marcus; Van den Mooter Guy
Physical stability of the amorphous state of loperamide and two fragment molecules in solid dispersions with the polymers PVP-K30 and PVP-VA64.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;25(2-3):313-20.
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2005: Six Karel; Daems Tinne; de Hoon Jan; Van Hecken Anne; Depre Marleen; Bouche Marie-Paule; Prinsen Paul; Verreck Geert; Peeters Jef; Brewster Marcus E; Van den Mooter Guy
Clinical study of solid dispersions of itraconazole prepared by hot-stage extrusion.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;24(2-3):179-86.
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2005: Verbeke K; de Preter V; Geboes K; Daems T; van den Mooter G; Evenepoel P; Rutgeerts P
In vivo evaluation of a colonic delivery system using isotope techniques.
Alimentary pharmacology & therapeutics 2005;21(2):187-94.
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2005: Weuts Ilse; Kempen Dieter; Verreck Geert; Decorte Annelies; Heymans Koen; Peeters Jef; Brewster Marcus; Van den Mooter Guy
Study of the physicochemical properties and stability of solid dispersions of loperamide and PEG6000 prepared by spray drying.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;59(1):119-26.
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2004: Justin-Temu Mary; Damian Festo; Kinget Renaat; Van Den Mooter Guy
Intravaginal gels as drug delivery systems.
Journal of women's health (2002) 2004;13(7):834-44.
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2004: Weuts Ilse; Kempen Dieter; Decorte Annelies; Verreck Geert; Peeters Jef; Brewster Marcus; Van den Mooter Guy
Phase behaviour analysis of solid dispersions of loperamide and two structurally related compounds with the polymers PVP-K30 and PVP-VA64.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;22(5):375-85.
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2004: Dillen Kathleen; Vandervoort Jo; Van den Mooter Guy; Verheyden Loes; Ludwig Annick
Factorial design, physicochemical characterisation and activity of ciprofloxacin-PLGA nanoparticles.
International journal of pharmaceutics 2004;275(1-2):171-87.
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2004: Wang Xin; Michoel Armand; Van den Mooter Guy
Study of the phase behavior of polyethylene glycol 6000-itraconazole solid dispersions using DSC.
International journal of pharmaceutics 2004;272(1-2):181-7.
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2004: Six Karel; Verreck Geert; Peeters Jef; Brewster Marcus; Van Den Mooter Guy
Increased physical stability and improved dissolution properties of itraconazole, a class II drug, by solid dispersions that combine fast- and slow-dissolving polymers.
Journal of pharmaceutical sciences 2004;93(1):124-31.
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2003: Six Karel; Berghmans Hugo; Leuner Christian; Dressman Jennifer; Van Werde Kristof; Mullens Jules; Benoist Luc; Thimon Mireille; Meublat Laurent; Verreck Geert; Peeters Jef; Brewster Marcus; Van den Mooter Guy
Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion, Part II.
Pharmaceutical research 2003;20(7):1047-54.
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2003: Di Fabio Simonetta; Van Roey Jens; Giannini Giacomo; van den Mooter Guy; Spada Massimo; Binelli Andrea; Pirillo Maria F; Germinario Elena; Belardelli Filippo; de Bethune Marie-Pierre; Vella Stefano
Inhibition of vaginal transmission of HIV-1 in hu-SCID mice by the non-nucleoside reverse transcriptase inhibitor TMC120 in a gel formulation.
AIDS (London, England) 2003;17(11):1597-604.
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2003: Weuts I; Kempen D; Six K; Peeters J; Verreck G; Brewster M; Van den Mooter G
Evaluation of different calorimetric methods to determine the glass transition temperature and molecular mobility below T(g) for amorphous drugs.
International journal of pharmaceutics 2003;259(1-2):17-25.
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2003: Van Nijlen T; Brennan K; Van den Mooter G; Blaton N; Kinget R; Augustijns P
Improvement of the dissolution rate of artemisinin by means of supercritical fluid technology and solid dispersions.
International journal of pharmaceutics 2003;254(2):173-81.
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2003: Van den Mooter Guy; Vervoort Lies; Kinget Renaat
Characterization of methacrylated inulin hydrogels designed for colon targeting: in vitro release of BSA.
Pharmaceutical research 2003;20(2):303-7.
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2003: Six Karel; Murphy John; Weuts Ilse; Craig Duncan Q M; Verreck Geert; Peeters Jef; Brewster Marcus; Van den Mooter Guy
Identification of phase separation in solid dispersions of itraconazole and Eudragit E100 using microthermal analysis.
Pharmaceutical research 2003;20(1):135-8.
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2003: Verreck Geert; Six Karel; Van den Mooter Guy; Baert Lieven; Peeters Jef; Brewster Marcus E
Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion--Part I.
International journal of pharmaceutics 2003;251(1-2):165-74.
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2002: Verheyen S; Blaton N; Kinget R; Van den Mooter G
Mechanism of increased dissolution of diazepam and temazepam from polyethylene glycol 6000 solid dispersions.
International journal of pharmaceutics 2002;249(1-2):45-58.
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2002: Rau J; Maris B; Kinget R; Samyn C; Van Den Mooter G; Stolz A
Enhanced anaerobic degradation of polymeric azo compounds by Escherichia coli in the presence of low-molecular-weight redox mediators.
The Journal of pharmacy and pharmacology 2002;54(11):1471-9.
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2002: Ndindayino F; Vervaet C; Van den Mooter G; Remon J P
Bioavailability of hydrochlorothiazide from isomalt-based moulded tablets.
International journal of pharmaceutics 2002;246(1-2):199-202.
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2002: Damian F; Blaton N; Kinget R; Van den Mooter G
Physical stability of solid dispersions of the antiviral agent UC-781 with PEG 6000, Gelucire 44/14 and PVP K30.
International journal of pharmaceutics 2002;244(1-2):87-98.
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2002: van Gelder J; Deferme S; Naesens L; De Clercq E; van den Mooter G; Kinget R; Augustijns P
Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined ester mixtures.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(8):924-30.
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2002: De Brabander C; Van Den Mooter G; Vervaet C; Remon J P
Characterization of ibuprofen as a nontraditional plasticizer of ethyl cellulose.
Journal of pharmaceutical sciences 2002;91(7):1678-85.
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2002: Ndindayino F; Vervaet C; Van den Mooter G; Remon J P
Direct compression and moulding properties of co-extruded isomalt/drug mixtures.
International journal of pharmaceutics 2002;235(1-2):159-68.
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2002: Ndindayino F; Henrist D; Kiekens F; Van den Mooter G; Vervaet C; Remon J P
Direct compression properties of melt-extruded isomalt.
International journal of pharmaceutics 2002;235(1-2):149-57.
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2002: Deferme S; Van Gelder J; Ingels F; Van den Mooter G; De Buck S; Balzarini J; Naesens L; De Clercq E; Kinget R; Augustijns P
Intestinal absorption characteristics of the low solubility thiocarboxanilide UC-781.
International journal of pharmaceutics 2002;234(1-2):113-9.
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2002: Maris B; Verheyden L; Samyn C; Augustijns P; Kinget R; Van den Mooter G
Influence of the composition of in-vitro azo-reducing systems on the degradation kinetics of the model compound amaranth.
The Journal of pharmacy and pharmacology 2002;54(2):197-203.
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2002: Ingels F; Deferme S; Destexhe E; Oth M; Van den Mooter G; Augustijns P
Simulated intestinal fluid as transport medium in the Caco-2 cell culture model.
International journal of pharmaceutics 2002;232(1-2):183-92.
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2002: Cavalcanti Osvaldo Albuquerque; Van den Mooter Guy; Caramico-Soares Ida; Kinget Renaat
Polysaccharides as excipients for colon-specific coatings. Permeability and swelling properties of casted films.
Drug development and industrial pharmacy 2002;28(2):157-64.
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2001: Verheyen S; Augustijns P; Kinget R; Van den Mooter G
Determination of partial solubility parameters of five benzodiazepines in individual solvents.
International journal of pharmaceutics 2001;228(1-2):199-207.
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2001: Van Den Mooter G; Craig D Q; Royall P G
Characterization of amorphous ketoconazole using modulated temperature differential scanning calorimetry.
Journal of pharmaceutical sciences 2001;90(8):996-1003.
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2001: Damian F; Blaton N; Desseyn H; Clou K; Augustijns P; Naesens L; Balzarini J; Kinget R; Van den Mooter G
Solid state properties of pure UC-781 and solid dispersions with polyvinylpyrrolidone (PVP K30).
The Journal of pharmacy and pharmacology 2001;53(8):1109-16.
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2001: Stubbe B; Maris B; Van den Mooter G; De Smedt S C; Demeester J
The in vitro evaluation of 'azo containing polysaccharide gels' for colon delivery.
Journal of controlled release : official journal of the Controlled Release Society 2001;75(1-2):103-14.
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2001: Shafiee M; Deferme S; Villard A L; Egron D; Gosselin G; Imbach J L; Lioux T; Pompon A; Varray S; Aubertin A M; Van Den Mooter G; Kinget R; Périgaud C; Augustijns P
New bis(SATE) prodrug of AZT 5'-monophosphate: in vitro anti-HIV activity, stability, and potential oral absorption.
Journal of pharmaceutical sciences 2001;90(4):448-63.
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2001: Six K; Verreck G; Peeters J; Augustijns P; Kinget R; Van den Mooter G
Characterization of glassy itraconazole: a comparative study of its molecular mobility below T(g) with that of structural analogues using MTDSC.
International journal of pharmaceutics 2001;213(1-2):163-73.
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2001: Maris B; Verheyden L; Van Reeth K; Samyn C; Augustijns P; Kinget R; Van den Mooter G
Synthesis and characterisation of inulin-azo hydrogels designed for colon targeting.
International journal of pharmaceutics 2001;213(1-2):143-52.
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2001: Van den Mooter G; Wuyts M; Blaton N; Busson R; Grobet P; Augustijns P; Kinget R
Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;12(3):261-9.
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2000: Van Gelder J; Deferme S; Annaert P; Naesens L; De Clercq E; Van den Mooter G; Kinget R; Augustijns P
Increased absorption of the antiviral ester prodrug tenofovir disoproxil in rat ileum by inhibiting its intestinal metabolism.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(12):1394-6.
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2000: Van Gelder J; Shafiee M; De Clercq E; Penninckx F; Van den Mooter G; Kinget R; Augustijns P
Species-dependent and site-specific intestinal metabolism of ester prodrugs.
International journal of pharmaceutics 2000;205(1-2):93-100.
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2000: Annaert P; Tukker J J; van Gelder J; Naesens L; de Clercq E; van Den Mooter G; Kinget R; Augustijns P
In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil.
Journal of pharmaceutical sciences 2000;89(8):1054-62.
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2000: Uchenna Agu R; Jorissen M; Willems T; Van den Mooter G; Kinget R; Verbeke N; Augustijns P
Safety assessment of selected cyclodextrins - effect on ciliary activity using a human cell suspension culture model exhibiting in vitro ciliogenesis.
International journal of pharmaceutics 2000;193(2):219-26.
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2000: Damian F; Blaton N; Naesens L; Balzarini J; Kinget R; Augustijns P; Van den Mooter G
Physicochemical characterization of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;10(4):311-22.
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1999: Ugwoke M I; Exaud S; Van Den Mooter G; Verbeke N; Kinget R
Bioavailability of apomorphine following intranasal administration of mucoadhesive drug delivery systems in rabbits.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;9(2):213-9.
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1999: Agu R U; Jorissen M; Willems T; Van den Mooter G; Kinget R; Augustijns P
Effects of pharmaceutical compounds on ciliary beating in human nasal epithelial cells: a comparative study of cell culture models.
Pharmaceutical research 1999;16(9):1380-5.
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1999: Van Gelder J; Witvrouw M; Pannecouque C; Henson G; Bridger G; Naesens L; De Clercq E; Annaert P; Shafiee M; Van den Mooter G; Kinget R; Augustijns P
Evaluation of the potential of ion pair formation to improve the oral absorption of two potent antiviral compounds, AMD3100 and PMPA.
International journal of pharmaceutics 1999;186(2):127-36.
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1999: Van den Mooter G; Augustijns P; Kinget R
Stability prediction of amorphous benzodiazepines by calculation of the mean relaxation time constant using the Williams-Watts decay function.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1999;48(1):43-8.
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1999: Van Gelder J; Annaert P; Naesens L; De Clercq E; Van den Mooter G; Kinget R; Augustijns P
Inhibition of intestinal metabolism of the antiviral ester prodrug bis(POC)-PMPA by nature-identical fruit extracts as a strategy to enhance its oral absorption: an in vitro study.
Pharmaceutical research 1999;16(7):1035-40.
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1999: Damian F; Van den Mooter G; Samyn C; Kinget R
In vitro biodegradation study of acetyl and methyl inulins by Bifidobacteria and inulinase.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1999;47(3):275-82.
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1999: Ikechukwu Ugwoke M; Sam E; Van Den Mooter G; Verbeke N; Kinget R
Nasal mucoadhesive delivery systems of the anti-parkinsonian drug, apomorphine: influence of drug-loading on in vitro and in vivo release in rabbits.
International journal of pharmaceutics 1999;181(1):125-38.
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1999: Vervoort L; Vinckier I; Moldenaers P; Van den Mooter G; Augustijns P; Kinget R
Inulin hydrogels as carriers for colonic drug targeting. Rheological characterization of the hydrogel formation and the hydrogel network.
Journal of pharmaceutical sciences 1999;88(2):209-14.
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1998: Van den Mooter G; Stas G; Damian F; Naesens L; Balzarini J; Kinget R; Augustijns P
Stability of UC-781, in intestinal mucosal homogenates of the rat, rabbit, and pig.
Pharmaceutical research 1998;15(11):1799-802.
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1998: Annaert P; Van Gelder J; Naesens L; De Clercq E; Van den Mooter G; Kinget R; Augustijns P
Carrier mechanisms involved in the transepithelial transport of bis(POM)-PMEA and its metabolites across Caco-2 monolayers.
Pharmaceutical research 1998;15(8):1168-73.
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1998: Naesens L; Bischofberger N; Augustijns P; Annaert P; Van den Mooter G; Arimilli M N; Kim C U; De Clercq E
Antiretroviral efficacy and pharmacokinetics of oral bis(isopropyloxycarbonyloxymethyl)-9-(2-phosphonylmethoxypropyl)adenine in mice.
Antimicrobial agents and chemotherapy 1998;42(7):1568-73.
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1998: Annaert P; Gosselin G; Pompon A; Benzaria S; Valette G; Imbach J L; Naesens L; Hatse S; de Clercq E; Van den Mooter G; Kinget R; Augustijns P
Comparison of the disposition of ester prodrugs of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine [PMEA] in Caco-2 monolayers.
Pharmaceutical research 1998;15(2):239-45.
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1998: Kinget R; Kalala W; Vervoort L; van den Mooter G
Colonic drug targeting.
Journal of drug targeting 1998;6(2):129-49.
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1997: Vervoort L; Van den Mooter G; Augustijns P; Busson R; Toppet S; Kinget R
Inulin hydrogels as carriers for colonic drug targeting: I. Synthesis and characterization of methacrylated inulin and hydrogel formation.
Pharmaceutical research 1997;14(12):1730-7.
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1997: Van den Mooter G; Maris B; Samyn C; Augustijns P; Kinget R
Use of azo polymers for colon-specific drug delivery.
Journal of pharmaceutical sciences 1997;86(12):1321-7.
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1995: Van den Mooter G; Samyn C; Kinget R
In vivo evaluation of a colon-specific drug delivery system: an absorption study of theophylline from capsules coated with azo polymers in rats.
Pharmaceutical research 1995;12(2):244-7.
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1994: Van den Mooter G; Samyn C; Kinget R
The relation between swelling properties and enzymatic degradation of azo polymers designed for colon-specific drug delivery.
Pharmaceutical research 1994;11(12):1737-41.
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