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Jan van der Gugten

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Chemicals & Drugs

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Startle Reaction

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Sanneke A M van Vliet; Raymond A P Vanwersch; Marjan J Jongsma; Jan van der Gugten; Berend Olivier; Ingrid H C H M Philippens
Neuroprotective effects of modafinil in a marmoset Parkinson model: behavioral and neurochemical aspects.
M J V van Bogaert; Lucianne Groenink; Ronald S Oosting; K G C Westphal; Jan van der Gugten; Berend Olivier
Mouse strain differences in autonomic responses to stress.
Aniko Korosi; Jan Veening; Tamás Kozicz; Marloes Henckens; Jos Dederen; Lucianne Groenink; Jan van der Gugten; Berend Olivier; Eric W Roubos
Distribution and expression of CRF receptor 1 and 2 mRNAs in the CRF over-expressing mouse brain.

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2006: Sanneke A M van Vliet; Raymond A P Vanwersch; Marjan J Jongsma; Jan van der Gugten; Berend Olivier; Ingrid H C H M Philippens
Neuroprotective effects of modafinil in a marmoset Parkinson model: behavioral and neurochemical aspects.
Behavioural pharmacology 2006;17(5-6):453-62.
2006: M J V van Bogaert; Lucianne Groenink; Ronald S Oosting; K G C Westphal; Jan van der Gugten; Berend Olivier
Mouse strain differences in autonomic responses to stress.
Genes, brain, and behavior 2006;5(2):139-49.
2006: Aniko Korosi; Jan Veening; Tamás Kozicz; Marloes Henckens; Jos Dederen; Lucianne Groenink; Jan van der Gugten; Berend Olivier; Eric W Roubos
Distribution and expression of CRF receptor 1 and 2 mRNAs in the CRF over-expressing mouse brain.
Brain research 2006;1072(1):46-54.
2005: Marieke van der Aa; Gerben A Koning; Jan van der Gugten; Christine d'Oliveira; Ronald S Oosting; Wim E Hennink; Daan J A Crommelin
Covalent attachment of an NLS-peptide to linear dna does not enhance transfection efficiency of cationic polymer based gene delivery systems.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):395-7.
2004: Jan Veening; Adriaan Bouwknecht; Henk J J Joosten; Pieter J W C Dederen; Theo J J Zethof; Lucianne Groenink; Jan van der Gugten; Berend Olivier
Stress-induced hyperthermia in the mouse: c-fos expression, corticosterone and temperature changes.
Progress in neuro-psychopharmacology & biological psychiatry 2004;28(4):699-707.
2004: Adriaan Bouwknecht; Jan van der Gugten; Lucianne Groenink; Berend Olivier; Richard Paylor
Behavioral and physiological mouse models for anxiety: effects of flesinoxan in 129S6/SvEvTac and C57BL/6J mice.
European journal of pharmacology 2004;494(1):45-53.
2004: Adriaan Bouwknecht; Jan van der Gugten; Lucianne Groenink; Berend Olivier; Richard Paylor
Effects of repeated testing in two inbred strains on flesinoxan dose-response curves in three mouse models for anxiety.
European journal of pharmacology 2004;494(1):35-44.
2004: Tamás Kozicz; Aniko Korosi; C Korsman; D Tilburg-Ouwens; Lucianne Groenink; Jan Veening; Jan van der Gugten; Eric W Roubos; Berend Olivier
Urocortin expression in the Edinger-Westphal nucleus is down-regulated in transgenic mice over-expressing neuronal corticotropin-releasing factor.
Neuroscience 2004;123(3):589-94.
2003: Reinoud de Jongh; Lucianne Groenink; Jan van der Gugten; Berend Olivier
Light-enhanced and fear-potentiated startle: temporal characteristics and effects of alpha-helical corticotropin-releasing hormone.
Biological psychiatry 2003;54(10):1041-8.
2003: Carin C E Overtoom; Marinus N Verbaten; Chantal Kemner; J Leon Kenemans; Herman van Engeland; Jan K Buitelaar; Maurits W van der Molen; Jan van der Gugten; Herman G M Westenberg; Robert A A Maes; Harry S Koelega
Effects of methylphenidate, desipramine, and L-dopa on attention and inhibition in children with Attention Deficit Hyperactivity Disorder.
Behavioural brain research 2003;145(1-2):7-15.
2003: Anneloes Dirks; Lucianne Groenink; Koen G C Westphal; Jocelien D A Olivier; P Monika Verdouw; Jan van der Gugten; Mark A Geyer; Berend Olivier
Reversal of startle gating deficits in transgenic mice overexpressing corticotropin-releasing factor by antipsychotic drugs.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(10):1790-8.
2003: Lucianne Groenink; M J V van Bogaert; Jan van der Gugten; Ronald S Oosting; Berend Olivier
5-HT1A receptor and 5-HT1B receptor knockout mice in stress and anxiety paradigms.
Behavioural pharmacology 2003;14(5-6):369-83.
2003: Tommy Pattij; Laus M Broersen; Judith van der Linde; Lucianne Groenink; Jan van der Gugten; Robert A A Maes; Berend Olivier
Operant learning and differential-reinforcement-of-low-rate 36-s responding in 5-HT1A and 5-HT1B receptor knockout mice.
Behavioural brain research 2003;141(2):137-45.
2003: Lucianne Groenink; Tommy Pattij; Reinoud de Jongh; Jan van der Gugten; Ronald S Oosting; Anneloes Dirks; Berend Olivier
5-HT1A receptor knockout mice and mice overexpressing corticotropin-releasing hormone in models of anxiety.
European journal of pharmacology 2003;463(1-3):185-97.
2003: Berend Olivier; Theo Zethof; Tommy Pattij; Meg van Boogaert; Ruud van Oorschot; Christina Leahy; Ronald S Oosting; Arjan Bouwknecht; Jan Veening; Jan van der Gugten; Lucianne Groenink
Stress-induced hyperthermia and anxiety: pharmacological validation.
European journal of pharmacology 2003;463(1-3):117-32.
2002: Anneloes Dirks; Lucianne Groenink; Adriaan Bouwknecht; Theo Hijzen; Jan van der Gugten; Eric Ronken; Sjef Verbeek; Jan Veening; Pieter J W C Dederen; Aniko Korosi; Louise F Schoolderman; Eric W Roubos; Berend Olivier
Overexpression of corticotropin-releasing hormone in transgenic mice and chronic stress-like autonomic and physiological alterations.
The European journal of neuroscience 2002;16(9):1751-60.
2002: Tommy Pattij; Lucianne Groenink; Theo Hijzen; Ronald S Oosting; Robert A A Maes; Jan van der Gugten; Berend Olivier
Autonomic changes associated with enhanced anxiety in 5-HT(1A) receptor knockout mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;27(3):380-90.
2002: Anneloes Dirks; Eric W Fish; Takefumi Kikusui; Jan van der Gugten; Lucianne Groenink; Berend Olivier; Klaus Miczek
Effects of corticotropin-releasing hormone on distress vocalizations and locomotion in maternally separated mouse pups.
Pharmacology, biochemistry, and behavior 2002;72(4):993-9.
2002: Tommy Pattij; Lucianne Groenink; Ronald S Oosting; Jan van der Gugten; Robert A A Maes; Berend Olivier
GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background.
European journal of pharmacology 2002;447(1):67-74.
2002: Lucianne Groenink; Anneloes Dirks; P Monika Verdouw; Marlies lutje Schipholt; Jan Veening; Jan van der Gugten; Berend Olivier
HPA axis dysregulation in mice overexpressing corticotropin releasing hormone.
Biological psychiatry 2002;51(11):875-81.
2002: Anneloes Dirks; Lucianne Groenink; Marlies Iutje Schipholt; Jan van der Gugten; Theo Hijzen; Mark A Geyer; Berend Olivier
Reduced startle reactivity and plasticity in transgenic mice overexpressing corticotropin-releasing hormone.
Biological psychiatry 2002;51(7):583-90.
2002: Reinoud de Jongh; Lucianne Groenink; Jan van der Gugten; Berend Olivier
The light-enhanced startle paradigm as a putative animal model for anxiety: effects of chlordiazepoxide, flesinoxan and fluvoxamine.
Psychopharmacology 2002;159(2):176-80.
2002: Adriaan Bouwknecht; Theo Hijzen; Jan van der Gugten; Robert A A Maes; René Hen; Berend Olivier
5-HT(1B) receptor knockout mice show no adaptive changes in 5-HT(1A) receptor function as measured telemetrically on body temperature and heart rate responses.
Brain research bulletin 2002;57(1):93-102.
2001: Adriaan Bouwknecht; Jan van der Gugten; Theo Hijzen; Robert A A Maes; René Hen; Berend Olivier
Male and female 5-HT(1B) receptor knockout mice have higher body weights than wildtypes.
Physiology & behavior 2001;74(4-5):507-16.
2001: Anneloes Dirks; Reinoud de Jongh; Lucianne Groenink; Jan van der Gugten; Theo Hijzen; Berend Olivier
Footshock-induced sensitization of the acoustic startle response in two strains of mice.
Behavioural brain research 2001;123(1):17-21.
2001: Tommy Pattij; Theo Hijzen; Lucianne Groenink; Ronald S Oosting; Jan van der Gugten; Robert A A Maes; René Hen; Berend Olivier
Stress-induced hyperthermia in the 5-HT(1A) receptor knockout mouse is normal.
Biological psychiatry 2001;49(7):569-74.
2001: Adriaan Bouwknecht; Theo Hijzen; Jan van der Gugten; Robert A A Maes; René Hen; Berend Olivier
Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice.
Biological psychiatry 2001;49(7):557-68.
2001: Adriaan Bouwknecht; Jan van der Gugten; Theo Hijzen; Robert A A Maes; René Hen; Berend Olivier
Corticosterone responses in 5-HT1B receptor knockout mice to stress or 5-HT1A receptor activation are normal.
Psychopharmacology 2001;153(4):484-90.
2001: Anneloes Dirks; Tommy Pattij; Adriaan Bouwknecht; T T Westphal; Theo Hijzen; Lucianne Groenink; Jan van der Gugten; Ronald S Oosting; René Hen; Mark A Geyer; Berend Olivier
5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response.
Behavioural brain research 2001;118(2):169-78.
2000: Adriaan Bouwknecht; Theo Hijzen; Jan van der Gugten; Anneloes Dirks; Robert A A Maes; René Hen; Mark A Geyer; Berend Olivier
Startle responses, heart rate, and temperature in 5-HT1B receptor knockout mice.
Neuroreport 2000;11(18):4097-102.
2000: Rosana M Sibug; JC Compaan; OC Meijer; Jan van der Gugten; Berend Olivier; Ron de Kloet
Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus.
European journal of pharmacology 2000;404(1-2):111-9.
2000: Adriaan Bouwknecht; Theo Hijzen; Jan van der Gugten; Robert A A Maes; René Hen; Berend Olivier
Ethanol intake is not elevated in male 5-HT(1B) receptor knockout mice.
European journal of pharmacology 2000;403(1-2):95-8.
2000: Adriaan Bouwknecht; Theo Hijzen; Jan van der Gugten; Robert A A Maes; Berend Olivier
Stress-induced hyperthermia in mice: effects of flesinoxan on heart rate and body temperature.
European journal of pharmacology 2000;400(1):59-66.
1999: J Gommans; Theo Hijzen; Tommy Pattij; Jan van der Gugten; Berend Olivier
Discriminative stimulus properties of mCPP and alprazolam are not mediated by anxiety.
Pharmacology, biochemistry, and behavior 1999;64(2):385-7.
1999: Berend Olivier; J Gommans; Jan van der Gugten; Adriaan Bouwknecht; AH Herremans; T Patty; Theo Hijzen
Stimulus properties of the selective 5-HT reuptake inhibitor fluvoxamine in conditioned taste aversion procedures.
Pharmacology, biochemistry, and behavior 1999;64(2):213-20.
1998: Rosana M Sibug; JC Compaan; OC Meijer; Jan van der Gugten; Berend Olivier; Ron de Kloet
Flesinoxan treatment reduces 5-HT1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels.
European journal of pharmacology 1998;353(2-3):207-14.
1997: Lucianne Groenink; Jan van der Gugten; JC Compaan; Robert A A Maes; Berend Olivier
Flesinoxan pretreatment differentially affects corticosterone, prolactin and behavioural responses to a flesinoxan challenge.
Psychopharmacology 1997;131(1):93-100.
1997: JC Compaan; Lucianne Groenink; Jan van der Gugten; Robert A A Maes; Berend Olivier
Pretreatment with 5-HT1A receptor agonist flesinoxan attenuates Fos protein in rat hypothalamus.
European journal of pharmacology 1997;324(2-3):161-8.
1996: JC Compaan; Lucianne Groenink; Jan van der Gugten; Robert A A Maes; Berend Olivier
5-HT1A receptor agonist flesinoxan enhances Fos immunoreactivity in rat central amygdala, bed nucleus of the stria terminalis and hypothalamus.
The European journal of neuroscience 1996;8(11):2340-7.
1996: Lucianne Groenink; J Mos; Jan van der Gugten; Berend Olivier
The 5-HT1A receptor is not involved in emotional stress-induced rises in stress hormones.
Pharmacology, biochemistry, and behavior 1996;55(2):303-8.
1996: Lucianne Groenink; Jan van der Gugten; T J Zethof; JA Van der Heyden; Berend Olivier
Neuroendocrine effects of diazepam and flesinoxan in the stress-induced hyperthermia test in mice.
Pharmacology, biochemistry, and behavior 1996;54(1):249-54.
1995: Lucianne Groenink; JC Compaan; Jan van der Gugten; T Zethof; JA Van der Heyden; Berend Olivier
Stress-induced hyperthermia in mice. Pharmacological and endocrinological aspects.
Annals of the New York Academy of Sciences 1995;771():252-6.
1995: T H van Leeuwen; Marinus N Verbaten; Harry S Koelega; J L Slangen; Jan van der Gugten; Gert Camfferman
Effects of oxazepam on event-related brain potentials, EEG frequency bands, and vigilance performance.
Psychopharmacology 1995;122(3):244-62.
1995: Lucianne Groenink; Jan van der Gugten; P M Verdouw; Robert A A Maes; Berend Olivier
The anxiolytic effects of flesinoxan, a 5-HT1A receptor agonist, are not related to its neuroendocrine effects.
European journal of pharmacology 1995;280(2):185-93.
1995: Lucianne Groenink; Jan van der Gugten; J Mos; Robert A A Maes; Berend Olivier
The corticosterone-enhancing effects of the 5-HT1A receptor antagonist, (S)-UH301, are not mediated by the 5-HT1A receptor.
European journal of pharmacology 1995;272(2-3):177-83.
1994: T H van Leeuwen; Marinus N Verbaten; Harry S Koelega; Gert Camfferman; Jan van der Gugten; J L Slangen
Effects of oxazepam on performance and event-related brain potentials in vigilance tasks with static and dynamic stimuli.
Psychopharmacology 1994;116(4):499-507.
1994: Lucianne Groenink; Jan van der Gugten; T Zethof; JA Van der Heyden; Berend Olivier
Stress-induced hyperthermia in mice: hormonal correlates.
Physiology & behavior 1994;56(4):747-9.
1994: T H van Leeuwen; Marinus N Verbaten; Harry S Koelega; Gert Camfferman; Jan van der Gugten; J L Slangen
Effects of oxazepam on eye movements and performance in vigilance tasks with static and dynamic stimuli.
Psychopharmacology 1994;114(1):109-18.
1994: Lucianne Groenink; Jan van der Gugten; J Mos; Robert A A Maes; Berend Olivier
(S)-UH301, a silent 5-HT1A receptor antagonist, enhances plasma corticosterone levels in the rat.
Life sciences 1994;55(5):PL99-103.
1991: H Van Herck; Vera Baumans; S F de Boer; Jan van der Gugten; A B van Woerkom; Anton C Beynen
Endocrine stress response in rats subjected to singular orbital puncture while under diethyl-ether anaesthesia.
Laboratory animals 1991;25(4):325-9.
1991: J W van der Laan; S F de Boer; Jan van der Gugten; G de Groot
Differences in the duration of sedative and anxiolytic effects of desmethyldiazepam in two outbred Wistar strains.
Pharmacology, biochemistry, and behavior 1991;39(1):149-53.
1991: S F De Boer; J L Slangen; Jan van der Gugten
Effects of buspirone and chlordiazepoxide on plasma catecholamine and corticosterone levels in stressed and nonstressed rats.
Pharmacology, biochemistry, and behavior 1991;38(2):299-308.
1991: S F De Boer; Jan van der Gugten; J L Slangen
Effects of chlordiazepoxide, flumazenil and DMCM on plasma catecholamine and corticosterone concentrations in rats.
Pharmacology, biochemistry, and behavior 1991;38(1):13-9.
1990: S F De Boer; Sietse Jan Koopmans; J L Slangen; Jan van der Gugten
Plasma catecholamine, corticosterone and glucose responses to repeated stress in rats: effect of interstressor interval length.
Physiology & behavior 1990;47(6):1117-24.
1990: S F De Boer; J L Slangen; Jan van der Gugten
Plasma catecholamine and corticosterone levels during active and passive shock-prod avoidance behavior in rats: effects of chlordiazepoxide.
Physiology & behavior 1990;47(6):1089-98.
1990: S F De Boer; Jan van der Gugten; J L Slangen
Brain benzodiazepine receptor-mediated effects on plasma catecholamine and corticosterone concentrations in rats.
Brain research bulletin 1990;24(6):843-7.
1990: S F de Boer; R de Beun; J L Slangen; Jan van der Gugten
Dynamics of plasma catecholamine and corticosterone concentrations during reinforced and extinguished operant behavior in rats.
Physiology & behavior 1990;47(4):691-8.
1990: S F de Boer; J L Slangen; Jan van der Gugten
Effects of chlordiazepoxide and buspirone on plasma catecholamine and corticosterone levels in rats under basal and stress conditions.
Endocrinologia experimentalis 1990;24(1-2):229-39.
1990: J P van Bergeijk; H Van Herck; S F de Boer; Gert W Meijer; AP Hesp; Jan van der Gugten; Anton C Beynen
Effects of group size and gentling on behaviour, selected organ masses and blood constituents in female Rivm: TOX rats.
Zeitschrift für Versuchstierkunde 1990;33(2):85-90.
1989: S F De Boer; Sietse Jan Koopmans; J L Slangen; Jan van der Gugten
Effects of fasting on plasma catecholamine, corticosterone and glucose concentrations under basal and stress conditions in individual rats.
Physiology & behavior 1989;45(5):989-94.
1989: S F De Boer; Jan van der Gugten; J L Slangen
Plasma catecholamine and corticosterone responses to predictable and unpredictable noise stress in rats.
Physiology & behavior 1989;45(4):789-95.
1988: S F de Boer; Jan van der Gugten; J L Slangen; Theo Hijzen
Changes in plasma corticosterone and catecholamine contents induced by low doses of deltamethrin in rats.
Toxicology 1988;49(2-3):263-70.
1988: S F De Boer; J L Slangen; Jan van der Gugten
Adaptation of plasma catecholamine and corticosterone responses to short-term repeated noise stress in rats.
Physiology & behavior 1988;44(2):273-80.
1987: S F De Boer; Jan van der Gugten
Daily variations in plasma noradrenaline, adrenaline and corticosterone concentrations in rats.
Physiology & behavior 1987;40(3):323-8.
1984: Theo Hijzen; Jan van der Gugten; L Bouter
Active and passive coping under different degrees of stress; effects on urinary and plasma catecholamines and ECG T-wave.
Biological psychology 1984;18(1):23-32.