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Jeroen van der Kaay

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Ian H Batty; Jeroen van der Kaay; Alex Gray; Joan F Telfer; Miles J Dixon; C Peter Downes
The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.
C Peter Downes; Nick R Leslie; Ian H Batty; Jeroen van der Kaay
Metabolic switching of PI3K-dependent lipid signals.
Satish Patel; Jeroen van der Kaay; Calum Sutherland
Insulin regulation of hepatic insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target of rapamycin (mTOR) signalling is impaired by the presence of hydrogen peroxide.

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All Publications

2007: Ian H Batty; Jeroen van der Kaay; Alex Gray; Joan F Telfer; Miles J Dixon; C Peter Downes
The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.
The Biochemical journal 2007;407(2):255-66.
2007: C Peter Downes; Nick R Leslie; Ian H Batty; Jeroen van der Kaay
Metabolic switching of PI3K-dependent lipid signals.
Biochemical Society transactions 2007;35(Pt 2):188-92.
2002: Satish Patel; Jeroen van der Kaay; Calum Sutherland
Insulin regulation of hepatic insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target of rapamycin (mTOR) signalling is impaired by the presence of hydrogen peroxide.
The Biochemical journal 2002;365(Pt 2):537-45.
2002: Thomas Radimerski; Jacques Montagne; Felix Rintelen; Hugo Stocker; Jeroen van der Kaay; C Peter Downes; Ernst Hafen; George Thomas
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.
Nature cell biology 2002;4(3):251-5.
2001: E Hill; O Olusanya; Jeroen van der Kaay; C Peter Downes; Paul D Andrews; Jason R Swedlow; Elizabeth Smythe
Regulation of clathrin-coated vesicle formation.
Biochemical Society transactions 2001;29(Pt 4):375-7.
2001: E Hill; Jeroen van der Kaay; C Peter Downes; Elizabeth Smythe
The role of dynamin and its binding partners in coated pit invagination and scission.
The Journal of cell biology 2001;152(2):309-23.
2000: Michayla R Williams; J Simon C Arthur; A Balendran; Jeroen van der Kaay; V Poli; Philip Cohen; Dario R Alessi
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells.
Current biology : CB 2000;10(8):439-48.
2000: Jenni Harvey; Neil G McKay; KS Walker; Jeroen van der Kaay; C Peter Downes; Michael L J Ashford
Essential role of phosphoinositide 3-kinase in leptin-induced K(ATP) channel activation in the rat CRI-G1 insulinoma cell line.
The Journal of biological chemistry 2000;275(7):4660-9.
1999: Alex Gray; Jeroen van der Kaay; C Peter Downes
The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo.
The Biochemical journal 1999;344 Pt 3():929-36.
1999: Jeroen van der Kaay; M Beck; Alex Gray; C Peter Downes
Distinct phosphatidylinositol 3-kinase lipid products accumulate upon oxidative and osmotic stress and lead to different cellular responses.
The Journal of biological chemistry 1999;274(50):35963-8.
1998: Michael P Myers; Ian Pass; Ian H Batty; Jeroen van der Kaay; JP Stolarov; B A Hemmings; Michael Wigler; C Peter Downes; Nicholas K Tonks
The lipid phosphatase activity of PTEN is critical for its tumor supressor function.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13513-8.
1998: E del Río; T Shinomura; Jeroen van der Kaay; David G Nicholls; C Peter Downes
Disruption by lithium of phosphoinositide signalling in cerebellar granule cells in primary culture.
Journal of neurochemistry 1998;70(4):1662-9.
1998: Jeroen van der Kaay; P J Cullen; C Peter Downes
Phosphatidylinositol(3,4,5)trisphosphate (Ptdins(3,4,5)P3) mass measurement using a radioligand displacement assay.
Methods in molecular biology (Clifton, N.J.) 1998;105():109-25.
1997: Darren A E Cross; Peter W Watt; M Shaw; Jeroen van der Kaay; C Peter Downes; Julie C Holder; Philip Cohen
Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue.
FEBS letters 1997;406(1-2):211-5.
1997: Jeroen van der Kaay; Ian H Batty; Darren A E Cross; Peter W Watt; C Peter Downes
A novel, rapid, and highly sensitive mass assay for phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) and its application to measure insulin-stimulated PtdIns(3,4,5)P3 production in rat skeletal muscle in vivo.
The Journal of biological chemistry 1997;272(9):5477-81.