FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Tom van der Poll

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Physiology

Disorders

Co-author Network

Publications

TOP 3
Xinglin Zhang; Rob J L Willems; Damien Bierschenk; Marc J M Bonten; Mark de Been; Masja Leendertse; Malbert Rogers; Janetta Top; Tom van der Poll; Willem van Schaik
Identification of a Genetic Determinant in Clinical Enterococcus faecium Strains That Contributes to Intestinal Colonization During Antibiotic Treatment.
Tim J Schuijt; Tom van der Poll; Willem M de Vos; W Joost Wiersinga
The intestinal microbiota and host immune interactions in the critically ill.
Jan Willem Duitman; Tom van der Poll; Arie J Hoogendijk; C Arnold Spek
CCAAT/enhancer-binding protein δ: multifaceted regulator in respiratory disease.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Tom van der Poll (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Xinglin Zhang; Rob J L Willems; Damien Bierschenk; Marc J M Bonten; Mark de Been; Masja Leendertse; Malbert Rogers; Janetta Top; Tom van der Poll; Willem van Schaik
Identification of a Genetic Determinant in Clinical Enterococcus faecium Strains That Contributes to Intestinal Colonization During Antibiotic Treatment.
The Journal of infectious diseases 2013;207(11):1780-6.
2013: Tim J Schuijt; Tom van der Poll; Willem M de Vos; W Joost Wiersinga
The intestinal microbiota and host immune interactions in the critically ill.
Trends in microbiology 2013;21(5):221-9.
2013: Jan Willem Duitman; Tom van der Poll; Arie J Hoogendijk; C Arnold Spek
CCAAT/enhancer-binding protein δ: multifaceted regulator in respiratory disease.
The American journal of pathology 2013;182(4):1459.
2013: Marcel Schouten; Cornelis van 't Veer; Edward M Conway; J Daan de Boer; Marcel Levi; Joost C M Meijers; Joris J T H Roelofs; Tom van der Poll
The lectin-like domain of thrombomodulin hampers host defence in pneumococcal pneumonia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2013;41(4):935-42.
2013: Arie Johan Hoogendijk; Sandra Sofia Pinhanços; Tom van der Poll; Catharina Wilhelmina Wieland
Intrapulmonary administration of a p38 mitogen activated protein kinase inhibitor partially prevents pulmonary inflammation.
Immunobiology 2013;218(4):435-42.
2013: Arie J Hoogendijk; Sandra S Pinhanços; Tom van der Poll; Catharina W Wieland
AMP-activated protein kinase activation by 5-aminoimidazole-4-carbox-amide-1-β-D-ribofuranoside (AICAR) reduces lipoteichoic acid-induced lung inflammation.
The Journal of biological chemistry 2013;288(10):7047-52.
2013: Marcel Levi; Tom van der Poll
Thrombomodulin in sepsis.
Minerva anestesiologica 2013;79(3):294-8.
2013: J Daan de Boer; Regina de Beer; Onno J de Boer; Alex F de Vos; Tijmen J Hommes; Arie J Hoogendijk; Joris J T H Roelofs; Marcel Schouten; Ingrid Stroo; jaring s. van der zee; Cornelis Van't Veer; Tom van der Poll
Lipopolysaccharide inhibits Th2 lung inflammation induced by house dust mite allergens in mice.
American journal of respiratory cell and molecular biology 2013;48(3):382-9.
2013: Jarom Heijmans; E Hoff; Daan W Hommes; Vanesa Muncan; Izak Biemond; A Bierhaus; N V J A Büller; Ashwin A Dihal; James C H Hardwick; Tom van der Poll; M A D van Zoelen; Gijs R van den Brink
Rage signalling promotes intestinal tumourigenesis.
Oncogene 2013;32(9):1202-6.
2013: L M Kager; J C M Meijers; Joris J T H Roelofs; Willem Joost Wiersinga; Sacha Zeerleder; Cornelis van 't Veer; Charles T Esmon; Tom van der Poll
Endogenous protein C has a protective role during Gram-negative pneumosepsis (melioidosis).
Journal of thrombosis and haemostasis : JTH 2013;11(2):282-92.
2013: Marcel Levi; Tom van der Poll
Disseminated intravascular coagulation: a review for the internist.
Internal and emergency medicine 2013;8(1):23-32.
2013: Cornelis P C de Jager; Eugenie F A Gemen; Mirrian Hilbink; Robert J F Laheij; Jacqueline Leuvenink; Tom van der Poll; Peter C Wever
Dynamics of peripheral blood lymphocyte subpopulations in the acute and subacute phase of legionnaires' disease.
PloS one 2013;8(4):e62265.
2013: Dana C Blok; Onno J de Boer; Alex F de Vos; Sandrine Florquin; Koenraad F van der Sluijs; Cornelis van 't Veer; Tom van der Poll
Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia.
PloS one 2013;8(3):e58191.
2013: Jorrit J Hofstra; Marcel Levi; Joris J T H Roelofs; Hamid Aslami; Alexander D Cornet; Paul J Declerck; Barry Dixon; Tom van der Poll; Alexander P J Vlaar; Marcus J Schultz
Nebulized fibrinolytic agents improve pulmonary fibrinolysis but not inflammation in rat models of direct and indirect acute lung injury.
PloS one 2013;8(2):e55262.
2013: G J Glas; J-J H Hofstra; Marcus Schultz; Tom van der Poll; Koenraad F van der Sluijs; Marcel Levi
Bronchoalveolar hemostasis in lung injury and acute respiratory distress syndrome.
Journal of thrombosis and haemostasis : JTH 2013;11(1):17-25.
2012: JanWillem Duitman; Sandrine Florquin; Angelique P Groot; Arie J Hoogendijk; Roberta R Ruela de Sousa; Tom van der Poll; C Arnold Spek
CCAAT-enhancer binding protein delta (C/EBPδ) protects against Klebsiella pneumoniae-induced pulmonary infection: potential role for macrophage migration.
The Journal of infectious diseases 2012;206(12):1826-35.
2012: Daniel Paris; Rattanaxay Phetsouvanh; Tom van der Poll; stuart blacksell; V Chansamouth; Arjen M Dondorp; S J Lee; M Levi; E C Löwenberg; P Nawtaisong; Paul N Newton; N P J Day
Coagulation and inflammation in scrub typhus and murine typhus--a prospective comparative study from Laos.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2012;18(12):1221-8.
2012: Miriam H P van Lieshout; Cornelis van 't Veer; Catharina W Wieland; Dana C Blok; Alex F de Vos; Tom van der Poll
Differential roles of MyD88 and TRIF in hematopoietic and resident cells during murine gram-negative pneumonia.
The Journal of infectious diseases 2012;206(9):1415-23.
2012: Tom van der Poll
Preclinical sepsis models.
Surgical infections 2012;13(5):287-92.
2012: Arie J Hoogendijk; Maria T Kuipers; Marcus J Schultz; Tom van der Poll; Catharina W Wieland
Cyclin-dependent kinase inhibition reduces lung damage in a mouse model of ventilator-induced lung injury.
Shock (Augusta, Ga.) 2012;38(4):375-80.
2012: Marieke A D van Zoelen; Catharina W Wieland; Gerritje J W van der Windt; Angelika Bierhaus; Sandrine Florquin; Peter P Nawroth; Tom van der Poll
Receptor for advanced glycation end products is protective during murine tuberculosis.
Molecular immunology 2012;52(3-4):183-9.
2012: Tom van der Poll; Marcel Levi
Crosstalk between inflammation and coagulation: the lessons of sepsis.
Current vascular pharmacology 2012;10(5):632-8.
2012: Liesbeth M Kager; Gerritje J W van der Windt; Catharina W Wieland; Cornelis van 't Veer; Sandrine Florquin; Tom van der Poll
Plasminogen activator inhibitor type I may contribute to transient, non-specific changes in immunity in the subacute phase of murine tuberculosis.
Microbes and infection / Institut Pasteur 2012;14(9):748-55.
2012: Liesbeth M Kager; Marcel Levi; Joost C M Meijers; Joris J T H Roelofs; Cornelis Van't Veer; W Joost Wiersinga; Tom van der Poll
Endogenous tissue-type plasminogen activator impairs host defense during severe experimental Gram-negative sepsis (melioidosis)*.
Critical care medicine 2012;40(7):2168-75.
2012: Marcel Levi; Tom van der Poll; Marcus Schultz
Infection and inflammation as risk factors for thrombosis and atherosclerosis.
Seminars in thrombosis and hemostasis 2012;38(5):506-14.
2012: Gerritje J W van der Windt; Cornelis Van't Veer; Dana C Blok; Alex F de Vos; Richard A Flavell; Sandrine Florquin; Jacobien J Hoogerwerf; Koichi S Kobayashi; Adriana J J Lammers; Tom van der Poll
Interleukin 1 receptor-associated kinase m impairs host defense during pneumococcal pneumonia.
The Journal of infectious diseases 2012;205(12):1849-57.
2012: Janwillem Duitman; Sandrine Florquin; Angelique P Groot; Marcel Schouten; Joost B Daalhuisen; Tom van der Poll; C Arnold Spek
CCAAT/enhancer-binding protein δ facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(23):9113-8.
2012: Maria T Kuipers; Jaklien C Leemans; Joris J T H Roelofs; Marcus J Schultz; Fayyaz S Sutterwala; Tom van der Poll; Koenraad F van der Sluijs; Alexander P J Vlaar; Hamid Aslami; Paul Bresser; Goda Choi; Richard A Flavell; John R Janczy; Esther K Wolthuis; Catharina W Wieland
Ventilator-induced lung injury is mediated by the NLRP3 inflammasome.
Anesthesiology 2012;116(5):1104-15.
2012: Tassili A F Weehuizen; Catharina W Wieland; Louis Boon; Nicholas P J Day; Jan-Willem Duitman; Sharon J Peacock; Tom van der Poll; Gerritje J W van der Windt; W Joost Wiersinga
Expression and function of transforming growth factor β in melioidosis.
Infection and immunity 2012;80(5):1853-7.
2012: J Daan de Boer; Christof J Majoor; Elisabeth H D Bel; Cornelis van 't Veer; Tom van der Poll
Asthma and coagulation.
Blood 2012;119(14):3236-44.
2012: Marcel Levi; Tom van der Poll; M Schultz
New insights into pathways that determine the link between infection and thrombosis.
The Netherlands journal of medicine 2012;70(3):114-20.
2012: Maria T Kuipers; Joris J T H Roelofs; Marcus J Schultz; Anita M Tuip-de Boer; Tom van der Poll; Alexander P J Vlaar; Hamid Aslami; Maria A Hegeman; Geartsje Jongsma; Nicole P Juffermans; Catharina W Wieland
Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury.
PloS one 2012;7(11):e50559.
2012: Ahmed Achouiti; Alex F de Vos; Sandrine Florquin; Tijmen J Hommes; Marc Röhm; Johannes Roth; Constantin F Urban; Cornelis van 't Veer; Marieke A D van Zoelen; Thomas Vogl; Tom van der Poll
Myeloid-related protein-14 contributes to protective immunity in gram-negative pneumonia derived sepsis.
PLoS pathogens 2012;8(10):e1002987.
2012: Hanna K de Jong; Chris M Parry; Tom van der Poll; W Joost Wiersinga
Host-pathogen interaction in invasive Salmonellosis.
PLoS pathogens 2012;8(10):e1002933.
2012: Cornelis P C de Jager; Eugenie F A Gemen; Ron Kusters; Tom van der Poll; Rianne van Gageldonk-Lafeber; Peter C Wever; Robert J F Laheij
The neutrophil-lymphocyte count ratio in patients with community-acquired pneumonia.
PloS one 2012;7(10):e46561.
2012: Frederic Reynier; jaring s. van der zee; Paul Bresser; Alex F de Vos; Jacobien J Hoogerwerf; Bruno Mougin; Alexandre Pachot; Malick Paye; Tom van der Poll
Gene expression profiles in alveolar macrophages induced by lipopolysaccharide in humans.
Molecular medicine (Cambridge, Mass.) 2012;18():1303-11.
2012: Jacobien J Hoogerwerf; Koichi S Kobayashi; Gerritje J W van der Windt; Cornelis van 't Veer; Dana C Blok; Alex F de Vos; Richard A Flavell; Sandrine Florquin; Arie J Hoogendijk; Tom van der Poll
Interleukin-1 receptor-associated kinase M-deficient mice demonstrate an improved host defense during Gram-negative pneumonia.
Molecular medicine (Cambridge, Mass.) 2012;18():1067-75.
2012: Adriana J J Lammers; Onno J de Boer; Sandrine Florquin; Alexander P N A de Porto; Tom van der Poll
The role of TLR2 in the host response to pneumococcal pneumonia in absence of the spleen.
BMC infectious diseases 2012;12():139.
2012: Arie J Hoogendijk; Joris J T H Roelofs; Tom van der Poll; Miriam H P van Lieshout; Dana C Blok; Janwillem Duitman; Catharina W Wieland
R-roscovitine reduces lung inflammation induced by lipoteichoic acid and Streptococcus pneumoniae.
Molecular medicine (Cambridge, Mass.) 2012;18():1086-95.
2012: Barry Mook-Kanamori; Dirk Troost; Madelijn Geldhoff; Tom van der Poll; Diederik van de Beek
Characterization of a pneumococcal meningitis mouse model.
BMC infectious diseases 2012;12():71.
2011: Marcel Schouten; Cornelis van 't Veer; Bruce Gerlitz; Brian W Grinnell; Marcel Levi; Joris J T H Roelofs; Tom van der Poll
Recombinant activated protein C attenuates coagulopathy and inflammation when administered early in murine pneumococcal pneumonia.
Thrombosis and haemostasis 2011;106(6):1189-96.
2011: Cornelis van 't Veer; Alex F de Vos; Sandrine Florquin; Daniëlle Kruijswijk; Petra S van den Pangaart; Tom van der Poll
Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli.
The Journal of biological chemistry 2011;286(42):36603-18.
2011: Alexander D Cornet; A B Johan Groeneveld; Jorrit J Hofstra; Marcel Levi; Joris J T H Roelofs; Floor E van den Boogaard; Tom van der Poll; Alexander P Vlaar; Marcus J Schultz
Nebulized anticoagulants limit coagulopathy but not inflammation in pseudomonas aeruginosa-induced pneumonia in rats.
Shock (Augusta, Ga.) 2011;36(4):417-23.
2011: L M Kager; Marcel Levi; Joost C M Meijers; Joris J T H Roelofs; Cornelis Van't Veer; Willem Joost Wiersinga; Tom van der Poll
Plasminogen activator inhibitor type I contributes to protective immunity during experimental Gram-negative sepsis (melioidosis).
Journal of thrombosis and haemostasis : JTH 2011;9(10):2020-8.
2011: Marcel Schouten; Koenraad F van der Sluijs; Cornelis Van't Veer; J Daan de Boer; Charles T Esmon; Marcel Levi; Joris J T H Roelofs; Tom van der Poll
Impact of endogenous protein C on pulmonary coagulation and injury during lethal H1N1 influenza in mice.
American journal of respiratory cell and molecular biology 2011;45(4):789-94.
2011: Tim Schuijt; Alje P Van Dam; Tom van der Poll; Cornelis Van't Veer; Diana Wouters; Mieke Brouwer; Jeroen Coumou; Jianfeng Dai; Kathleen DePonte; Joppe Hovius; Sukanya Narasimhan; Anneke Oei; Joris J T H Roelofs; Erol Fikrig
A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent.
Cell host & microbe 2011;10(2):136-46.
2011: Lillemor Skattum; Tom van der Poll; Marcel van Deuren; Lennart Truedsson
Complement deficiency states and associated infections.
Molecular immunology 2011;48(14):1643-55.
2011: Adriana J Lammers; Hester J Bootsma; Onno J de Boer; Alexander P de Porto; Sandrine Florquin; Peter W Hermans; Tom van der Poll
Enhanced vulnerability for Streptococcus pneumoniae sepsis during asplenia is determined by the bacterial capsule.
Immunobiology 2011;216(8):863-70.
2011: Barry B Mook-Kanamori; Madelijn Geldhoff; Tom van der Poll; Diederik van de Beek
Pathogenesis and pathophysiology of pneumococcal meningitis.
Clinical microbiology reviews 2011;24(3):557-91.
2011: Marieke A D van Zoelen; Marleen I Verstege; Christian Draing; Regina de Beer; Sandrine Florquin; Paul Bresser; jaring s. van der zee; Anje A Te Velde; Sonja Von Aulock; Cornelis van't Veer; Tom van der Poll
Endogenous MCP-1 promotes lung inflammation induced by LPS and LTA.
Molecular immunology 2011;48(12-13):1468-76.
2011: Cetin Agar; Philip G de Groot; Bas de Laat; Heiko Herwald; Johannes Levels; Stephanie D D C Monk; Matthias Mörgelin; Rolf T Urbanus; Tom van der Poll; Gwendolyn van Os; Joost C M Meijers
β₂-glycoprotein I: a novel component of innate immunity.
Blood 2011;117(25):6939-47.
2011: Gerritje J W van der Windt; Arie J Hoogendijk; Marcel Schouten; Tijmen J Hommes; Alex F de Vos; Sandrine Florquin; Tom van der Poll
Osteopontin impairs host defense during pneumococcal pneumonia.
The Journal of infectious diseases 2011;203(12):1850-8.
2011: Jorrit J Hofstra; Paul Knape; Marcel Levi; Dave P Mackie; Goda Choi; Rogier M Determann; Tom van der Poll; Alexander P Vlaar; Marcus J Schultz
Pulmonary activation of coagulation and inhibition of fibrinolysis after burn injuries and inhalation trauma.
The Journal of trauma 2011;70(6):1389-97.
2011: Tom van der Poll; Johannes Daan de Boer; Marcel Levi
The effect of inflammation on coagulation and vice versa.
Current opinion in infectious diseases 2011;24(3):273-8.
2011: Tom van der Poll
Thrombin and diabetic nephropathy.
Blood 2011;117(19):5015-6.
2011: M Schouten; C van't Veer; Marcel Levi; Charles T Esmon; Tom van der Poll
Endogenous protein C inhibits activation of coagulation and transiently lowers bacterial outgrowth in murine Escherichia coli peritonitis.
Journal of thrombosis and haemostasis : JTH 2011;9(5):1072-5.
2011: Marcel Levi; Marcus Schultz; Tom van der Poll
Coagulation biomarkers in critically ill patients.
Critical care clinics 2011;27(2):281-97.
2011: Gerritje J W van der Windt; Arie J Hoogendijk; Alex F de Vos; Marjolein E Kerver; Sandrine Florquin; Tom van der Poll
The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia.
Laboratory investigation; a journal of technical methods and pathology 2011;91(4):588-97.
2011: C W Wieland; M H P van Lieshout; A J Hoogendijk; Tom van der Poll
Host defence during Klebsiella pneumonia relies on haematopoietic-expressed Toll-like receptors 4 and 2.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2011;37(4):848-57.
2011: Gavin C K W Koh; Rapeephan R Maude; M Fernanda Schreiber; Direk Limmathurotsakul; W Joost Wiersinga; Vanaporn Wuthiekanun; Sue J Lee; Weera Mahavanakul; Wipada Chaowagul; Wirongrong Chierakul; Nicholas J White; Tom van der Poll; Nicholas P J Day; Gordon Dougan; Sharon J Peacock
Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011;52(6):717-25.
2011: J Coumou; Tom van der Poll; P Speelman; Joppe Hovius
Tired of Lyme borreliosis. Lyme borreliosis in the Netherlands.
The Netherlands journal of medicine 2011;69(3):101-11.
2011: David J van Westerloo; Goda Choi; Ester C Löwenberg; Jasper Truijen; Alex F de Vos; Erik Endert; Joost C M Meijers; Lu Zhou; Manuel P F L Pereira; Karla C S Queiroz; Sander H Diks; Marcel Levi; Maikel Peppelenbosch; Tom van der Poll
Acute stress elicited by bungee jumping suppresses human innate immunity.
Molecular medicine (Cambridge, Mass.) 2011;17(3-4):180-8.
2011: Jasper Truijen; Shyrin C A T Davis; Wim J Stok; Yu-Sok Kim; David J van Westerloo; Marcel Levi; Tom van der Poll; Berend E Westerhof; John M Karemaker; Johannes J van Lieshout
Baroreflex sensitivity is higher during acute psychological stress in healthy subjects under β-adrenergic blockade.
Clinical science (London, England : 1979) 2011;120(4):161-7.
2011: Maria T Kuipers; Marcus J Schultz; Tom van der Poll; Catharina W Wieland
Bench-to-bedside review: Damage-associated molecular patterns in the onset of ventilator-induced lung injury.
Critical care (London, England) 2011;15(6):235.
2011: Henrike Veninga; Feng-Qi An; Alex M de Bruin; Alex F de Vos; Robert M Hoek; M Edward Medof; Tom van der Poll; René A W van Lier; Jörg Hamann
A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense.
PloS one 2011;6(10):e24431.
2011: Tom van der Poll; Marieke A D van Zoelen; W Joost Wiersinga
Regulation of pro-and anti-inflammatory host responses.
Contributions to microbiology 2011;17():125-36.
2011: Marga G A Goris; Jiri F P Wagenaar; Rudy A Hartskeerl; Eric C M van Gorp; Simone Schuller; Avril M Monahan; Jarlath E Nally; Tom van der Poll; Cornelis van 't Veer
Potent innate immune response to pathogenic leptospira in human whole blood.
PloS one 2011;6(3):e18279.
2011: Arie J Hoogendijk; Sander H Diks; Tom van der Poll; Maikel P Peppelenbosch; Catharina W Wieland
Kinase activity profiling of pneumococcal pneumonia.
PloS one 2011;6(4):e18519.
2011: Femke Stephan; Tom van der Poll; Jw Olivier van Till; Walter A Wuillemin; Lucien A Aarden; Marja A Boermeester; Ingrid Bulder; Jan A Hazelzet; Sacha Zeerleder
Activation of factor VII-activating protease in human inflammation: a sensor for cell death.
Critical care (London, England) 2011;15(2):R110.
2011: Marieke A D van Zoelen; Ahmed Achouiti; Tom van der Poll
The role of receptor for advanced glycation endproducts (RAGE) in infection.
Critical care (London, England) 2011;15(2):208.
2011: Tim J Schuijt; Sukanya Narasimhan; Sirlei Daffre; Kathleen DePonte; Joppe Hovius; Cornelis Van't Veer; Tom van der Poll; Kamran Bakhtiari; Joost C M Meijers; Eric T Boder; Alje P Van Dam; Erol Fikrig
Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display.
PloS one 2011;6(1):e15926.
2011: F E Van Den Boogaard; X Brands; M J Schultz; Marcel Levi; Joris J T H Roelofs; Cornelis van 't Veer; Tom van der Poll
Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia.
Journal of thrombosis and haemostasis : JTH 2011;9(1):122-32.
2011: T J Schuijt; Joppe Hovius; Tom van der Poll; Alje P Van Dam; Erol Fikrig
Lyme borreliosis vaccination: the facts, the challenge, the future.
Trends in parasitology 2011;27(1):40-7.
2010: Leo A B Joosten; Frank van de Veerdonk; Alieke G Vonk; Otto C Boerman; Monique Keuter; Giamila Fantuzzi; Ineke Verschueren; Tom van der Poll; Charles A Dinarello; Bart Jan Kullberg; Jos W M van der Meer; Mihai G Netea
Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010;118(12):1000-7.
2010: M Schouten; Koenraad F van der Sluijs; Joris J T H Roelofs; Marcel Levi; C Van't Veer; Tom van der Poll
Factor V Leiden mutation does not affect coagulopathy or outcome in lethal H1N1 influenza.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;36(6):1346-54.
2010: G J W van der Windt; J J Hoogerwerf; Alex F de Vos; Sandrine Florquin; Tom van der Poll
Osteopontin promotes host defense during Klebsiella pneumoniae-induced pneumonia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;36(6):1337-45.
2010: Marcel Schouten; Cornelis van 't Veer; Florry E van den Boogaard; Bruce Gerlitz; Brian W Grinnell; Joris J T H Roelofs; Marcel Levi; Tom van der Poll
Therapeutic recombinant murine activated protein C attenuates pulmonary coagulopathy and improves survival in murine pneumococcal pneumonia.
The Journal of infectious diseases 2010;202(10):1600-7.
2010: Gerritje J W van der Windt; Sandrine Florquin; Alex F de Vos; Cornelis van't Veer; Karla C S Queiroz; Jiurong Liang; Dianhua Jiang; Paul W Noble; Tom van der Poll
CD44 deficiency is associated with increased bacterial clearance but enhanced lung inflammation during Gram-negative pneumonia.
The American journal of pathology 2010;177(5):2483-94.
2010: Catharina W Wieland; Sandrine Florquin; Tom van der Poll
Toll-like receptor 9 is not important for host defense against Haemophilus influenzae.
Immunobiology 2010;215(11):910-4.
2010: Sachin Yende; Tom van der Poll; Minjae Lee; David T Huang; Anne B Newman; Lan Kong; John A Kellum; Tamara B Harris; Doug Bauer; Suzanne Satterfield; Derek C Angus
The influence of pre-existing diabetes mellitus on the host immune response and outcome of pneumonia: analysis of two multicentre cohort studies.
Thorax 2010;65(10):870-7.
2010: Wilco P Pulskens; Elena Rampanelli; Gwendoline J D Teske; Loes M Butter; Nike Claessen; Ilse K Luirink; Tom van der Poll; Sandrine Florquin; Jaklien C Leemans
TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury.
Journal of the American Society of Nephrology : JASN 2010;21(8):1299-308.
2010: Marcel Levi; Marcus Schultz; Tom van der Poll
Disseminated intravascular coagulation in infectious disease.
Seminars in thrombosis and hemostasis 2010;36(4):367-77.
2010: Marieke A D van Zoelen; Ahmed Achouiti; Ann-Marie Schmidt; Huan Yang; Sandrine Florquin; Kevin Tracey; Tom van der Poll
Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis.
Critical care medicine 2010;38(6):1414-22.
2010: A A Anas; W Joost Wiersinga; Alex F de Vos; Tom van der Poll
Recent insights into the pathogenesis of bacterial sepsis.
The Netherlands journal of medicine 2010;68(4):147-52.
2010: Jacobien J Hoogerwerf; Michael W T Tanck; Marieke A D van Zoelen; Xavier Wittebole; Pierre-François Laterre; Tom van der Poll
Soluble ST2 plasma concentrations predict mortality in severe sepsis.
Intensive care medicine 2010;36(4):630-7.
2010: Jorrit J Hofstra; Alexander P Vlaar; Alexander D Cornet; Barry Dixon; Joris J Roelofs; Goda Choi; Tom van der Poll; Marcel Levi; Marcus J Schultz
Nebulized anticoagulants limit pulmonary coagulopathy, but not inflammation, in a model of experimental lung injury.
Journal of aerosol medicine and pulmonary drug delivery 2010;23(2):105-11.
2010: W Joost Wiersinga; Liesbeth M Kager; Joppe W R Hovius; Gerritje J W van der Windt; Alex F de Vos; Joost C M Meijers; Joris J Roelofs; Arjen Dondorp; Marcel Levi; Nicholas P Day; Sharon J Peacock; Tom van der Poll
Urokinase receptor is necessary for bacterial defense against pneumonia-derived septic melioidosis by facilitating phagocytosis.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(6):3079-86.
2010: Jacobien J Hoogerwerf; Alex F de Vos; Cornelis van't Veer; Paul Bresser; Anita de Boer; Michael W T Tanck; Christian Draing; jaring s. van der zee; Tom van der Poll
Priming of alveolar macrophages upon instillation of lipopolysaccharide in the human lung.
American journal of respiratory cell and molecular biology 2010;42(3):349-56.
2010: Masja Leendertse; Rob Willems; Roelof Flierman; Alex F de Vos; Marc J M Bonten; Tom van der Poll
The complement system facilitates clearance of Enterococcus faecium during murine peritonitis.
The Journal of infectious diseases 2010;201(4):544-52.
2010: Marcel Levi; Tom van der Poll
Inflammation and coagulation.
Critical care medicine 2010;38(2 Suppl):S26-34.
2010: Michiel E Stegenga; Jean-Louis Vincent; George M Vail; Jin Xie; Douglas J Haney; Mark D Williams; gordon bernard; Tom van der Poll
Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis.
Critical care medicine 2010;38(2):539-45.
2010: Cornelis P C de Jager; Paul T L van Wijk; Rejiv B Mathoera; Jacqueline de Jongh-Leuvenink; Tom van der Poll; Peter C Wever
Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit.
Critical care (London, England) 2010;14(5):R192.
2010: Mark C Dessing; Loes M Butter; Gwendoline J D Teske; Nike Claessen; Chris M van der Loos; Thomas Vogl; Johannes Roth; Tom van der Poll; Sandrine Florquin; Jaklien C Leemans
S100A8/A9 is not involved in host defense against murine urinary tract infection.
PloS one 2010;5(10):e13394.
2010: Gerritje J W van der Windt; W Joost Wiersinga; Catharina W Wieland; Ivo C S I Tjia; Nicholas P Day; Sharon J Peacock; Sandrine Florquin; Tom van der Poll
Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis).
PLoS neglected tropical diseases 2010;4(8):.
2010: Marcel Schouten; Cornelis van't Veer; Joris J T H Roelofs; Marcel Levi; Tom van der Poll
Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study.
Critical care (London, England) 2010;14(4):R145.
2010: Tom van der Poll; Joost C M Meijers
Systemic inflammatory response syndrome and compensatory anti-inflammatory response syndrome in sepsis.
Journal of innate immunity 2010;2(5):379-80.
2010: Jacobien J Hoogerwerf; Marieke A van Zoelen; W Joost Wiersinga; Cornelis van 't Veer; Alex F de Vos; Anita de Boer; Marcus J Schultz; Berend Hooibrink; Evert de Jonge; Tom van der Poll
Gene expression profiling of apoptosis regulators in patients with sepsis.
Journal of innate immunity 2010;2(5):461-8.
2010: Hanna Katrien de Jong; Tom van der Poll; Willem Joost Wiersinga
The systemic pro-inflammatory response in sepsis.
Journal of innate immunity 2010;2(5):422-30.
2010: Koenraad F van der Sluijs; Tom van der Poll; René Lutter; Nicole P Juffermans; Marcus J Schultz
Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications.
Critical care (London, England) 2010;14(2):219.
2010: Adam A Anas; Joppe W R Hovius; Cornelis van 't Veer; Tom van der Poll; Alex F de Vos
Role of CD14 in a mouse model of acute lung inflammation induced by different lipopolysaccharide chemotypes.
PloS one 2010;5(4):e10183.
2010: W Joost Wiersinga; Thierry Calandra; Liesbeth M Kager; Gerritje J W van der Windt; Thierry Roger; Didier le Roy; Sandrine Florquin; Sharon J Peacock; Fred C G J Sweep; Tom van der Poll
Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.
PLoS neglected tropical diseases 2010;4(2):e605.
2010: Gerritje J W van der Windt; Cornelis van 't Veer; Sandrine Florquin; Tom van der Poll
CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages.
Infection and immunity 2010;78(1):115-24.
2009: Marieke A D van Zoelen; Thomas Vogl; Dirk Foell; Suzanne Q van Veen; Jan Van Till; Sandrine Florquin; Michael W T Tanck; Xavier Wittebole; Pierre-François Laterre; Marja A Boermeester; Johannes Roth; Tom van der Poll
Expression and role of myeloid-related protein-14 in clinical and experimental sepsis.
American journal of respiratory and critical care medicine 2009;180(11):1098-106.
2009: Tom van der Poll; Steven M Opal
Pathogenesis, treatment, and prevention of pneumococcal pneumonia.
Lancet 2009;374(9700):1543-56.
2009: Masja Leendertse; Esther Heikens; Lucas M Wijnands; Miranda van Luit-Asbroek; Gwendoline J D Teske; Joris J T H Roelofs; Marc J M Bonten; Tom van der Poll; Rob Willems
Enterococcal surface protein transiently aggravates Enterococcus faecium-induced urinary tract infection in mice.
The Journal of infectious diseases 2009;200(7):1162-5.
2009: Gerritje J W van der Windt; Catharina W Wieland; Willem J Wiersinga; Sandrine Florquin; Tom van der Poll
Osteopontin is not crucial to protective immunity during murine tuberculosis.
Immunology 2009;128(1 Suppl):e766-76.
2009: Marieke A D van Zoelen; Ann-Marie Schmidt; Sandrine Florquin; Joost C Meijers; Regina de Beer; Alex F de Vos; Peter P Nawroth; Angelika Bierhaus; Tom van der Poll
Receptor for advanced glycation end products facilitates host defense during Escherichia coli-induced abdominal sepsis in mice.
The Journal of infectious diseases 2009;200(5):765-73.
2009: Masja Leendertse; Rob Willems; G Anneke Oei; Sandrine Florquin; Marc J M Bonten; Tom van der Poll
Intestinal Enterococcus faecium colonization improves host defense during polymicrobial peritonitis.
The Journal of infectious diseases 2009;200(5):735-44.
2009: Marieke A D van Zoelen; Koenraad F van der Sluijs; Ahmed Achouiti; Sandrine Florquin; Jennie M Braun-Pater; Huan Yang; Peter P Nawroth; Kevin Tracey; Angelika Bierhaus; Tom van der Poll
Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia.
Virology 2009;391(2):265-73.
2009: Masja Leendertse; Rob Willems; Ida A J Giebelen; Petra S van den Pangaart; Marc J M Bonten; Tom van der Poll
The acute-phase response impairs host defence against Enterococcus faecium peritonitis.
Immunology 2009;128(1 Suppl):e335-42.
2009: Mervyn D I Vergouwen; Joost C M Meijers; Ronald B Geskus; Bert A Coert; Janneke Horn; Erik S G Stroes; Tom van der Poll; Marinus Vermeulen; Y B W E M Roos
Biologic effects of simvastatin in patients with aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled randomized trial.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(8):1444-53.
2009: Alex F de Vos; Jennie M Pater; Petra S van den Pangaart; Martijn D de Kruif; Cornelis van 't Veer; Tom van der Poll
In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):533-42.
2009: W Joost Wiersinga; Tom van der Poll
Burkholderia pseudomallei tropism and the melioidosis road map.
The Journal of infectious diseases 2009;199(12):1720-2.
2009: Marieke A D van Zoelen; Sandrine Florquin; Regina de Beer; Jennie M Pater; Marleen I Verstege; Joost C M Meijers; Tom van der Poll
Urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury.
The American journal of pathology 2009;174(6):2182-9.
2009: Joppe Hovius; Maarten F Bijlsma; Gerritje J W van der Windt; W Joost Wiersinga; Bastiaan J D Boukens; Jeroen Coumou; Anneke Oei; Regina de Beer; Alex F de Vos; Cornelis van 't Veer; Alje P Van Dam; Penghua Wang; Erol Fikrig; Marcel M Levi; Joris J T H Roelofs; Tom van der Poll
The urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferi.
PLoS pathogens 2009;5(5):e1000447.
2009: Masja Leendertse; Rob Willems; Ida A J Giebelen; Sandrine Florquin; Petra S van den Pangaart; Marc J M Bonten; Tom van der Poll
Cecal ligation and puncture induced sepsis impairs host defense against Enterococcus faecium peritonitis.
Intensive care medicine 2009;35(5):924-32.
2009: Marcus J Schultz; Nicole P Juffermans; Tom van der Poll
A new twist on the legend of granulocyte colony-stimulating factor in acute lung injury?
Critical care medicine 2009;37(4):1506-7.
2009: Marieke A D van Zoelen; Marcel Schouten; Alex F de Vos; Sandrine Florquin; Joost C M Meijers; Peter P Nawroth; Angelika Bierhaus; Tom van der Poll
The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4349-56.
2009: Catharina W Wieland; Gerritje J W van der Windt; Sandrine Florquin; Andrew N J McKenzie; Tom van der Poll
ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
Microbes and infection / Institut Pasteur 2009;11(4):524-30.
2009: Willem J Wiersinga; Tom van der Poll
Immunity to Burkholderia pseudomallei.
Current opinion in infectious diseases 2009;22(2):102-8.
2009: Joris J T H Roelofs; Kasper M A Rouschop; Gwendoline J D Teske; Gerry T M Wagenaar; Nike Claessen; Jan J Weening; Tom van der Poll; Sandrine Florquin
Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(3):801-8.
2009: Esther K Wolthuis; Alexander P J Vlaar; Goda Choi; Joris J T H Roelofs; Jack J Haitsma; Tom van der Poll; Nicole P Juffermans; Machteld M Zweers; Marcus Schultz
Recombinant human soluble tumor necrosis factor-alpha receptor fusion protein partly attenuates ventilator-induced lung injury.
Shock (Augusta, Ga.) 2009;31(3):262-6.
2009: Masja Leendertse; Rob Willems; Ida A J Giebelen; Joris J T H Roelofs; Nico van Rooijen; Marc J M Bonten; Tom van der Poll
Peritoneal macrophages are important for the early containment of Enterococcus faecium peritonitis in mice.
Innate immunity 2009;15(1):3-12.
2009: Willem Joost Wiersinga; Cornelis Van't Veer; Petra S van den Pangaart; Arjen M Dondorp; Nicholas P Day; Sharon J Peacock; Tom van der Poll
Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis).
Critical care medicine 2009;37(2):569-76.
2009: Michiel E Stegenga; Sandrine Florquin; Alex F de Vos; Tom van der Poll
The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice.
Critical care medicine 2009;37(2):614-8.
2009: Jacobien J Hoogerwerf; Alex F de Vos; Marcel Levi; Paul Bresser; jaring s. van der zee; Christian Draing; Sonja Von Aulock; Tom van der Poll
Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide.
Critical care medicine 2009;37(2):619-25.
2009: Saskia N van der Crabben; Regje M E Blümer; Michiel E Stegenga; Mariëtte T Ackermans; Erik Endert; Michael W T Tanck; Mireille J Serlie; Tom van der Poll; Hans P Sauerwein
Early endotoxemia increases peripheral and hepatic insulin sensitivity in healthy humans.
The Journal of clinical endocrinology and metabolism 2009;94(2):463-8.
2009: I A J Giebelen; M Leendertse; Sandrine Florquin; Tom van der Poll
Stimulation of acetylcholine receptors impairs host defence during pneumococcal pneumonia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(2):375-81.
2009: Mark C Dessing; Koenraad F van der Sluijs; C Arnold Spek; Tom van der Poll
Gene expression profiles in murine influenza pneumonia.
Journal of innate immunity 2009;1(4):366-75.
2009: Mark C Dessing; Robert A Hirst; Alex F de Vos; Tom van der Poll
Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.
PloS one 2009;4(11):e7993.
2009: Jorrit J Hofstra; Alexander D Cornet; Bart F de Rooy; Alexander P Vlaar; Tom van der Poll; Marcel Levi; Sebastian Aj Zaat; Marcus J Schultz
Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats.
Critical care (London, England) 2009;13(5):R145.
2009: Masja Leendertse; Rob Willems; Ida A J Giebelen; Joris J T H Roelofs; Janetta Top; Marc J M Bonten; Tom van der Poll
Intestinal colonization with Enterococcus faecium does not influence pulmonary defense against Pseudomonas aeruginosa in mice.
PloS one 2009;4(8):e6775.
2009: Jiri F P Wagenaar; M Hussein Gasem; Marga G A Goris; Mariska Leeflang; Rudy A Hartskeerl; Tom van der Poll; Cornelis van 't Veer; Eric C M van Gorp
Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis.
PLoS neglected tropical diseases 2009;3(6):e453.
2009: Jaklien C Leemans; Loes M Butter; Wilco P C Pulskens; Gwendoline J D Teske; Nike Claessen; Tom van der Poll; Sandrine Florquin
The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury.
PloS one 2009;4(5):e5704.
2009: Sachin Yende; Tom van der Poll
Diabetes and sepsis outcomes--it is not all bad news.
Critical care (London, England) 2009;13(1):117.
2009: Esther Heikens; Masja Leendertse; Lucas M Wijnands; Miranda van Luit-Asbroek; Marc J M Bonten; Tom van der Poll; Rob Willems
Enterococcal surface protein Esp is not essential for cell adhesion and intestinal colonization of Enterococcus faecium in mice.
BMC microbiology 2009;9():19.
2009: Marjolein A van Maanen; Maria C Lebre; Tom van der Poll; Greg La Rosa; Daniel Elbaum; Margriet J Vervoordeldonk; Paul P Tak
Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice.
Arthritis and rheumatism 2009;60(1):114-22.
2008: Marcel Levi; Marcel Schouten; Tom van der Poll
Sepsis, coagulation, and antithrombin: old lessons and new insights.
Seminars in thrombosis and hemostasis 2008;34(8):742-6.
2008: Henrike Veninga; Susann Becker; Robert M Hoek; Manja Wobus; Elke Wandel; Jos van der Kaa; Martin van der Valk; Alex F de Vos; Hannelore Haase; Bronwyn Owens; Tom van der Poll; René A W van Lier; Sjef Verbeek; Gabriela Aust; Jörg Hamann
Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(9):6574-83.
2008: W Joost Wiersinga; Alex F de Vos; Catharina W Wieland; Masja Leendertse; Joris J T H Roelofs; Tom van der Poll
CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice.
The Journal of infectious diseases 2008;198(9):1388-97.
2008: Joppe Hovius; Tim Schuijt; K A de Groot; J J T H Roelofs; G A Oei; J A Marquart; R de Beer; C van 't Veer; Tom van der Poll; Nandhini Ramamoorthi; Erol Fikrig; Alje P Van Dam
Preferential protection of Borrelia burgdorferi sensu stricto by a Salp15 homologue in Ixodes ricinus saliva.
The Journal of infectious diseases 2008;198(8):1189-97.
2008: Catharina W Wieland; Gerritje J W van der Windt; W Joost Wiersinga; Sandrine Florquin; Tom van der Poll
CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
Immunology 2008;125(2):272-9.
2008: Ida A J Giebelen; Alain Le Moine; Petra S van den Pangaart; Claude Sadis; Michel Goldman; Sandrine Florquin; Tom van der Poll
Deficiency of alpha7 cholinergic receptors facilitates bacterial clearance in Escherichia coli peritonitis.
The Journal of infectious diseases 2008;198(5):750-7.
2008: Regje M E Blümer; Saskia N van der Crabben; Michiel E Stegenga; Michael W T Tanck; Mariëtte T Ackermans; Erik Endert; Tom van der Poll; Hans P Sauerwein
Hyperglycemia prevents the suppressive effect of hyperinsulinemia on plasma adiponectin levels in healthy humans.
American journal of physiology. Endocrinology and metabolism 2008;295(3):E613-7.
2008: Ida A J Giebelen; Masja Leendertse; Mark C Dessing; Joost C M Meijers; Marcel Levi; Christian Draing; Sonja Von Aulock; Tom van der Poll
Endogenous beta-adrenergic receptors inhibit lipopolysaccharide-induced pulmonary cytokine release and coagulation.
American journal of respiratory cell and molecular biology 2008;39(3):373-9.
2008: David J van Westerloo; Erik A J Rauws; Daan W Hommes; Alex F de Vos; Tom van der Poll; Barbara L Powers; Paul Fockens; Marcel GW Dijkgraaf; Marco J Bruno
Pre-ERCP infusion of semapimod, a mitogen-activated protein kinases inhibitor, lowers post-ERCP hyperamylasemia but not pancreatitis incidence.
Gastrointestinal endoscopy 2008;68(2):246-54.
2008: Marcel Levi; Tom van der Poll
The role of natural anticoagulants in the pathogenesis and management of systemic activation of coagulation and inflammation in critically ill patients.
Seminars in thrombosis and hemostasis 2008;34(5):459-68.
2008: W Joost Wiersinga; Mark C Dessing; Tom van der Poll
Gene-expression profiles in murine melioidosis.
Microbes and infection / Institut Pasteur 2008;10(8):868-77.
2008: Jacobien J Hoogerwerf; Alex F de Vos; Paul Bresser; jaring s. van der zee; Jennie M Pater; Anita de Boer; Michael W T Tanck; Daniel L Lundell; Chung Her-Jenh; Christian Draing; Sonja Von Aulock; Tom van der Poll
Lung inflammation induced by lipoteichoic acid or lipopolysaccharide in humans.
American journal of respiratory and critical care medicine 2008;178(1):34-41.
2008: Michiel E Stegenga; Saskia N van der Crabben; Regje M E Blümer; Marcel Levi; Joost C M Meijers; Mireille J Serlie; Michael W T Tanck; Hans P Sauerwein; Tom van der Poll
Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia.
Blood 2008;112(1):82-9.
2008: Cornelis van't Veer; Tom van der Poll
Keeping blood clots at bay in sepsis.
Nature medicine 2008;14(6):606-8.
2008: Gijs Hardenberg; Koen van der Sluijs; Tom van der Poll; Jan Paul Medema
APRIL affects antibody responses and early leukocyte infiltration, but not influenza A viral control.
Molecular immunology 2008;45(11):3050-8.
2008: Masja Leendertse; Rob Willems; Ida A J Giebelen; Petra S van den Pangaart; W Joost Wiersinga; Alex F de Vos; Sandrine Florquin; Marc J M Bonten; Tom van der Poll
TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4865-74.
2008: Marieke A D van Zoelen; Akitoshi Ishizaka; Esther K Wolthuls; Goda Choi; Tom van der Poll; Marcus Schultz
Pulmonary levels of high-mobility group box 1 during mechanical ventilation and ventilator-associated pneumonia.
Shock (Augusta, Ga.) 2008;29(4):441-5.
2008: Rosemarijn Renckens; Joris J T H Roelofs; M E Stegenga; Sandrine Florquin; Marcel Levi; Peter Carmeliet; Cornelis Van't Veer; Tom van der Poll
Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia.
Journal of thrombosis and haemostasis : JTH 2008;6(4):660-8.
2008: Ben J Appelmelk; Jeroen den Dunnen; N N Driessen; R Ummels; M Pak; Jerome Nigou; G Larrouy-Maumus; S S Gurcha; Farahnaz Movahedzadeh; J Geurtsen; E J Brown; M M Eysink Smeets; G S Besra; P T J Willemsen; Todd L Lowary; Yvette van Kooyk; JJ Maaskant; neil stoker; Peter van der Ley; G Puzo; Christina M.J.E, Vandenbroucke-Grauls; Catharina W Wieland; Tom van der Poll; Teunis B H Geijtenbeek; Astrid van der Sar; Wilbert Bitter
The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.
Cellular microbiology 2008;10(4):930-44.
2008: Martijn D de Kruif; Lucienne C Lemaire; Ida A J Giebelen; Angelique P Groot; Jennie M Pater; Petra S van den Pangaart; Peter J Elliott; Tom van der Poll
Effects of prednisolone on the systemic release of mediators of cell-mediated cytotoxicity during human endotoxemia.
Shock (Augusta, Ga.) 2008;29(4):458-61.
2008: Sylvia Knapp; Sonja Von Aulock; Masja Leendertse; Isabella Haslinger; Christian Draing; Douglas T Golenbock; Tom van der Poll
Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3478-84.
2008: Marieke A D van Zoelen; Sandrine Florquin; Joost C M Meijers; Regina de Beer; Alex F de Vos; Onno J de Boer; Tom van der Poll
Platelet-activating factor receptor contributes to host defense against Pseudomonas aeruginosa pneumonia but is not essential for the accompanying inflammatory and procoagulant response.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3357-65.
2008: Martijn D de Kruif; Lucienne C Lemaire; Ida A J Giebelen; Joachim Struck; Nils G. Morgenthaler; Jana Papassotiriou; Peter J Elliott; Tom van der Poll
The influence of corticosteroids on the release of novel biomarkers in human endotoxemia.
Intensive care medicine 2008;34(3):518-22.
2008: Marcel Schouten; Willem Joost Wiersinga; Marcel Levi; Tom van der Poll
Inflammation, endothelium, and coagulation in sepsis.
Journal of leukocyte biology 2008;83(3):536-45.
2008: Joppe Hovius; Marein A W P de Jong; Jeroen den Dunnen; Manja Litjens; Erol Fikrig; Tom van der Poll; Sonja I Gringhuis; Teunis B H Geijtenbeek
Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization.
PLoS pathogens 2008;4(2):e31.
2008: Rosemarijn Renckens; David J van Westerloo; Joris J T H Roelofs; Jennie M Pater; Marcus Schultz; Sandrine Florquin; Tom van der Poll
Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice.
Critical care medicine 2008;36(2):580-7.
2008: Mark C Dessing; Marcel Schouten; Christian Draing; Marcel Levi; Sonja Von Aulock; Tom van der Poll
Role played by Toll-like receptors 2 and 4 in lipoteichoic acid-induced lung inflammation and coagulation.
The Journal of infectious diseases 2008;197(2):245-52.
2008: Tom van der Poll
Tissue factor as an initiator of coagulation and inflammation in the lung.
Critical care (London, England) 2008;12 Suppl 6():S3.
2008: Wilco P Pulskens; Gwendoline J Teske; Loes M Butter; Joris J T H Roelofs; Tom van der Poll; Sandrine Florquin; Jaklien C Leemans
Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury.
PloS one 2008;3(10):e3596.
2008: W Joost Wiersinga; Catharina W Wieland; Joris J T H Roelofs; Tom van der Poll
MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei.
PloS one 2008;3(10):e3494.
2008: Marieke A D van Zoelen; Tom van der Poll
Targeting RAGE in sepsis.
Critical care (London, England) 2008;12(1):103.
2008: Esther K Wolthuis; Goda Choi; Mark C Dessing; Paul Bresser; René Lutter; Misa Dzoljic; Tom van der Poll; Margreeth B Vroom; Markus W Hollmann; Marcus Schultz
Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury.
Anesthesiology 2008;108(1):46-54.
2008: Goda Choi; Jorrit-Jan H Hofstra; Joris J T H Roelofs; Anita W Rijneveld; Paul Bresser; jaring s. van der zee; Sandrine Florquin; Tom van der Poll; Marcel Levi; Marcus Schultz
Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats.
Critical care medicine 2008;36(1):204-10.
2008: Tom van der Poll; Steven M Opal
Host-pathogen interactions in sepsis.
The Lancet infectious diseases 2008;8(1):32-43.
2008: W Joost Wiersinga; Joost C M Meijers; Marcel Levi; Cornelis van 't Veer; N P Day; S J Peacock; Tom van der Poll
Activation of coagulation with concurrent impairment of anticoagulant mechanisms correlates with a poor outcome in severe melioidosis.
Journal of thrombosis and haemostasis : JTH 2008;6(1):32-9.
2008: Mark C Dessing; Sandrine Florquin; James C Paton; Tom van der Poll
Toll-like receptor 2 contributes to antibacterial defence against pneumolysin-deficient pneumococci.
Cellular microbiology 2008;10(1):237-46.
2008: W Joost Wiersinga; Alex F de Vos; Regina de Beer; Catharina W Wieland; Joris J T H Roelofs; Donald E Woods; Tom van der Poll
Inflammation patterns induced by different Burkholderia species in mice.
Cellular microbiology 2008;10(1):81-7.
2007: W Joost Wiersinga; Cees van T Veer; Catharina W Wieland; Sébastien Gibot; Berend Hooibrink; Nicholas P J Day; Sharon J Peacock; Tom van der Poll
Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis.
The Journal of infectious diseases 2007;196(11):1707-16.
2007: Marieke A D van Zoelen; Pierre-François Laterre; Suzanne Q van Veen; Jan Van Till; Xavier Wittebole; Paul Bresser; Michael W T Tanck; Thierry Dugernier; Akitoshi Ishizaka; Marja A Boermeester; Tom van der Poll
Systemic and local high mobility group box 1 concentrations during severe infection.
Critical care medicine 2007;35(12):2799-804.
2007: Mark C Dessing; Koenraad F van der Sluijs; Sandrine Florquin; Tom van der Poll
Monocyte chemoattractant protein 1 contributes to an adequate immune response in influenza pneumonia.
Clinical immunology (Orlando, Fla.) 2007;125(3):328-36.
2007: Ida A J Giebelen; David J van Westerloo; Greg La Rosa; Alex F de Vos; Tom van der Poll
Local stimulation of alpha7 cholinergic receptors inhibits LPS-induced TNF-alpha release in the mouse lung.
Shock (Augusta, Ga.) 2007;28(6):700-3.
2007: Cornelis van 't Veer; Petra S van den Pangaart; Marieke A D van Zoelen; Martijn D de Kruif; Rakesh S Birjmohun; Eric S Stroes; Alex F de Vos; Tom van der Poll
Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):7110-20.
2007: Marieke A D van Zoelen; Alex F de Vos; Greg La Rosa; Christian Draing; Sonja Von Aulock; Tom van der Poll
Intrapulmonary delivery of ethyl pyruvate attenuates lipopolysaccharide- and lipoteichoic acid-induced lung inflammation in vivo.
Shock (Augusta, Ga.) 2007;28(5):570-5.
2007: Mark C Dessing; Koenraad F van der Sluijs; Sandrine Florquin; Tom van der Poll
CD14 plays a limited role during influenza A virus infection in vivo.
Immunology letters 2007;113(1):47-51.
2007: Catharina W Wieland; Sandrine Florquin; Tom van der Poll
Interleukin 18 participates in the early inflammatory response and bacterial clearance during pneumonia caused by nontypeable Haemophilus influenzae.
Infection and immunity 2007;75(10):5068-72.
2007: Willem Joost Wiersinga; Tom van der Poll
Is the septic response good or bad?
Current infectious disease reports 2007;9(5):366-73.
2007: Thomas Vogl; Klaus Tenbrock; Stephan Ludwig; Nadja Leukert; Christina Ehrhardt; Marieke A D van Zoelen; Wolfgang Nacken; Dirk Foell; Tom van der Poll; Clemens Sorg; Johannes Roth
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
Nature medicine 2007;13(9):1042-9.
2007: Goda Choi; A P J Vlaar; M Schouten; C Van't Veer; Tom van der Poll; Marcel Levi; Marcus Schultz
Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;30(3):423-8.
2007: Katarina Radosevic; Catharina W Wieland; Ariane Rodriguez; Gerrit Jan Weverling; Ratna Mintardjo; Gert Gillissen; Ronald Vogels; Yasir A W Skeiky; David Hone; Jerald C Sadoff; Tom van der Poll; Menzo J E Havenga; Jaap Goudsmit
Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon.
Infection and immunity 2007;75(8):4105-15.
2007: W Joost Wiersinga; Catharina W Wieland; Gerritje J W van der Windt; Anita de Boer; Sandrine Florquin; Arjen M Dondorp; Nicholas P J Day; Sharon J Peacock; Tom van der Poll
Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis.
Infection and immunity 2007;75(8):3739-46.
2007: W Joost Wiersinga; Catharina W Wieland; Mark C Dessing; Narisara Chantratita; Allen C Cheng; Direk Limmathurotsakul; Wirongrong Chierakul; Masja Leendertse; Sandrine Florquin; Alex F de Vos; Nicholas White; Arjen M Dondorp; Nicholas P J Day; Sharon J Peacock; Tom van der Poll
Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis).
PLoS medicine 2007;4(7):e248.
2007: Petra J G Zwijnenburg; Tom van der Poll; Sandrine Florquin; Machteld M J Polfliet; Timo K van den Berg; Christine D Dijkstra; John J Roord; C Erik Hack; A Marceline van Furth
C1 inhibitor treatment improves host defense in pneumococcal meningitis in rats and mice.
The Journal of infectious diseases 2007;196(1):115-23.
2007: W Joost Wiersinga; Mark C Dessing; Piet A Kager; Allen C Cheng; Direk Limmathurotsakul; Nicholas P J Day; Arjen M Dondorp; Tom van der Poll; Sharon J Peacock
High-throughput mRNA profiling characterizes the expression of inflammatory molecules in sepsis caused by Burkholderia pseudomallei.
Infection and immunity 2007;75(6):3074-9.
2007: Goda Choi; Jorrit-Jan H Hofstra; Joris J T H Roelofs; Sandrine Florquin; Paul Bresser; Marcel Levi; Tom van der Poll; Marcus Schultz
Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats.
Critical care medicine 2007;35(5):1362-8.
2007: Helmut Wittkowski; Anne B Sturrock; Marieke A D van Zoelen; Dorothee Viemann; Tom van der Poll; John R Hoidal; Johannes Roth; Dirk Foell
Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome.
Critical care medicine 2007;35(5):1369-75.
2007: Rakesh S Birjmohun; Sander I van Leuven; Johannes Levels; Cornelis van 't Veer; Jan Albert Kuivenhoven; Joost C M Meijers; Marcel Levi; John J P Kastelein; Tom van der Poll; Erik S G Stroes
High-density lipoprotein attenuates inflammation and coagulation response on endotoxin challenge in humans.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(5):1153-8.
2007: Mark C Dessing; Koenraad F van der Sluijs; Sandrine Florquin; Shizuo Akira; Tom van der Poll
Toll-like receptor 2 does not contribute to host response during postinfluenza pneumococcal pneumonia.
American journal of respiratory cell and molecular biology 2007;36(5):609-14.
2007: Ida A J Giebelen; David J van Westerloo; Greg La Rosa; Alex F de Vos; Tom van der Poll
Stimulation of alpha 7 cholinergic receptors inhibits lipopolysaccharide-induced neutrophil recruitment by a tumor necrosis factor alpha-independent mechanism.
Shock (Augusta, Ga.) 2007;27(4):443-7.
2007: Maaike de Fost; Wirongrong Chierakul; Roongreung Limpaiboon; Arjen M Dondorp; Nicholas J White; Tom van der Poll
Release of granzymes and chemokines in Thai patients with leptospirosis.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2007;13(4):433-6.
2007: Mark C Dessing; Sylvia Knapp; Sandrine Florquin; Alex F de Vos; Tom van der Poll
CD14 facilitates invasive respiratory tract infection by Streptococcus pneumoniae.
American journal of respiratory and critical care medicine 2007;175(6):604-11.
2007: Joppe Hovius; Xin Li; Nandhini Ramamoorthi; Alje P Van Dam; Stephen W Barthold; Tom van der Poll; Peter Speelman; Erol Fikrig
Coinfection with Borrelia burgdorferi sensu stricto and Borrelia garinii alters the course of murine Lyme borreliosis.
FEMS immunology and medical microbiology 2007;49(2):224-34.
2007: Gijs Th J van Well; Catharina W Wieland; Sandrine Florquin; John J Roord; Tom van der Poll; A Marceline van Furth
A new murine model to study the pathogenesis of tuberculous meningitis.
The Journal of infectious diseases 2007;195(5):694-7.
2007: Rosemarijn Renckens; Joris J T H Roelofs; Peter I Bonta; Sandrine Florquin; Carlie J M de Vries; Marcel Levi; Peter Carmeliet; Cornelis Van't Veer; Tom van der Poll
Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia.
Blood 2007;109(4):1593-601.
2007: Martijn D de Kruif; Lucienne C Lemaire; Ida A J Giebelen; Marieke A D van Zoelen; Jennie M Pater; Petra S van den Pangaart; Angelique P Groot; Alex F de Vos; Peter J Elliott; Joost C M Meijers; Marcel Levi; Tom van der Poll
Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1845-51.
2007: Catharina W Wieland; Estella A Koppel; Jeroen den Dunnen; Sandrine Florquin; Andrew N J McKenzie; Yvette van Kooyk; Tom van der Poll; Teunis B H Geijtenbeek
Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis.
Microbes and infection / Institut Pasteur 2007;9(2):134-41.
2007: Sylvia Knapp; Ulrich Matt; Norbert Leitinger; Tom van der Poll
Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(2):993-1001.
2007: Marcel Levi; Tom van der Poll
Recombinant human activated protein C: current insights into its mechanism of action.
Critical care (London, England) 2007;11 Suppl 5():S3.
2007: Nico A Maris; Alex F de Vos; Paul Bresser; jaring s. van der zee; Henk M Jansen; Marcel Levi; Tom van der Poll
Salmeterol enhances pulmonary fibrinolysis in healthy volunteers.
Critical care medicine 2007;35(1):57-63.
2006: Marieke A D van Zoelen; Kamran Bakhtiari; Mark C Dessing; Cornelis Van't Veer; C Arnold Spek; Michael W T Tanck; Joost C M Meijers; Tom van der Poll
Ethyl pyruvate exerts combined anti-inflammatory and anticoagulant effects on human monocytic cells.
Thrombosis and haemostasis 2006;96(6):789-93.
2006: Rosemarijn Renckens; Jennie M Pater; Tom van der Poll
Plasminogen activator inhibitor type-1-deficient mice have an enhanced IFN-gamma response to lipopolysaccharide and staphylococcal enterotoxin B.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):8171-6.
2006: Joris J T H Roelofs; Kasper M A Rouschop; Gwendoline J D Teske; Nike Claessen; Jan J Weening; Tom van der Poll; Sandrine Florquin
The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
Kidney international 2006;70(11):1942-7.
2006: Mark C Dessing; Alex F de Vos; Sandrine Florquin; Tom van der Poll
Monocyte chemoattractant protein 1 does not contribute to protective immunity against pneumococcal pneumonia.
Infection and immunity 2006;74(12):7021-3.
2006: Tymen T Keller; Koenraad F van der Sluijs; Martijn D de Kruif; V E A Gerdes; Joost C M Meijers; Sandrine Florquin; Tom van der Poll; Eric C M van Gorp; D P M Brandjes; Harry R Büller; Marcel Levi
Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1.
Circulation research 2006;99(11):1261-9.
2006: Kasper M A Rouschop; Marc Sylva; Gwendoline J D Teske; Inge Hoedemaeker; Steven T Pals; Jan J Weening; Tom van der Poll; Sandrine Florquin
Urothelial CD44 facilitates Escherichia coli infection of the murine urinary tract.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7225-32.
2006: Catharina W Wieland; Marjolein E Kerver; Sandrine Florquin; Martijn A Nolte; Jannie Borst; René A W van Lier; Marinus H J van Oers; Tom van der Poll
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
International immunology 2006;18(11):1531-9.
2006: Goda Choi; Esther K Wolthuis; Paul Bresser; Marcel Levi; Tom van der Poll; Misa Dzoljic; Margreeth B Vroom; Marcus Schultz
Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury.
Anesthesiology 2006;105(4):689-95.
2006: Peter I Bonta; Claudia M van Tiel; Mariska Vos; Thijs W H Pols; Johannes V van Thienen; Valerie Ferreira; E Karin Arkenbout; Jurgen Seppen; C Arnold Spek; Tom van der Poll; Hans Pannekoek; Carlie J M de Vries
Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2288-94.
2006: Nico A Maris; Mark C Dessing; Alex F de Vos; Paul Bresser; jaring s. van der zee; Henk M Jansen; C Arnold Spek; Tom van der Poll
Toll-like receptor mRNA levels in alveolar macrophages after inhalation of endotoxin.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;28(3):622-6.
2006: David J van Westerloo; Ida A J Giebelen; Joost C M Meijers; Joost Daalhuisen; Alex F de Vos; Marcel Levi; Tom van der Poll
Vagus nerve stimulation inhibits activation of coagulation and fibrinolysis during endotoxemia in rats.
Journal of thrombosis and haemostasis : JTH 2006;4(9):1997-2002.
2006: Catharina W Wieland; Sandrine Florquin; Jennie M Pater; Sebastiaan Weijer; Tom van der Poll
Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract.
Microbes and infection / Institut Pasteur 2006;8(9-10):2409-13.
2006: Rosemarijn Renckens; Joris J T H Roelofs; Sandrine Florquin; Alex F de Vos; Jennie M Pater; H Roger Lijnen; Peter Carmeliet; Cornelis van 't Veer; Tom van der Poll
Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1189-96.
2006: Michiel E Stegenga; Saskia N van der Crabben; Marcel Levi; Alex F de Vos; Michael W T Tanck; Hans P Sauerwein; Tom van der Poll
Hyperglycemia stimulates coagulation, whereas hyperinsulinemia impairs fibrinolysis in healthy humans.
Diabetes 2006;55(6):1807-12.
2006: Anita W Rijneveld; Sebastiaan Weijer; Paul Bresser; Sandrine Florquin; George P Vlasuk; William E Rote; C Arnold Spek; Pieter H Reitsma; jaring s. van der zee; Marcel Levi; Tom van der Poll
Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia.
Critical care medicine 2006;34(6):1725-30.
2006: Koenraad F van der Sluijs; Leontine J R van Elden; Yanling Xiao; Ramon Arens; Monique Nijhuis; Rob Schuurman; Sandrine Florquin; Henk M Jansen; René Lutter; Tom van der Poll
IL-12 deficiency transiently improves viral clearance during the late phase of respiratory tract infection with influenza A virus in mice.
Antiviral research 2006;70(2):75-84.
2006: David J van Westerloo; Ida A J Giebelen; Sandrine Florquin; Marco J Bruno; Greg La Rosa; Luis Ulloa; Kevin Tracey; Tom van der Poll
The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice.
Gastroenterology 2006;130(6):1822-30.
2006: Lucienne C Lemaire; Martijn D de Kruif; Ida A J Giebelen; Marcel Levi; Tom van der Poll; Michael Heesen
Dobutamine does not influence inflammatory pathways during human endotoxemia.
Critical care medicine 2006;34(5):1365-71.
2006: Catharina W Wieland; Michiel E Stegenga; Sandrine Florquin; Giamila Fantuzzi; Tom van der Poll
Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice.
Shock (Augusta, Ga.) 2006;25(4):414-9.
2006: Martijn Weisfelt; Jan de Gans; Tom van der Poll; Diederik van de Beek
Pneumococcal meningitis in adults: new approaches to management and prevention.
Lancet neurology 2006;5(4):332-42.
2006: W Joost Wiersinga; Tom van der Poll; Nicholas J White; Nicholas P Day; Sharon J Peacock
Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei.
Nature reviews. Microbiology 2006;4(4):272-82.
2006: Rosemarijn Renckens; Joris J T H Roelofs; Sandrine Florquin; Alex F de Vos; H Roger Lijnen; Cornelis Van't Veer; Tom van der Poll
Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3735-41.
2006: Goda Choi; Marcus Schultz; Marcel Levi; Tom van der Poll
The relationship between inflammation and the coagulation system.
Swiss medical weekly 2006;136(9-10):139-44.
2006: Petra J G Zwijnenburg; Tom van der Poll; John J Roord; A Marceline van Furth
Chemotactic factors in cerebrospinal fluid during bacterial meningitis.
Infection and immunity 2006;74(3):1445-51.
2006: Sylvia Knapp; Sandrine Florquin; Douglas T Golenbock; Tom van der Poll
Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):3189-95.
2006: Jaklien C Leemans; Catharina W Wieland; Sandrine Florquin; Tom van der Poll; Margriet J Vervoordeldonk
Mice overexpressing p40 in lungs have reduced leucocyte influx and slightly impaired resistance during tuberculosis.
Immunology 2006;117(3):409-18.
2006: Rosemarijn Renckens; Joris J T H Roelofs; Sandrine Florquin; Tom van der Poll
Urokinase-type plasminogen activator receptor plays a role in neutrophil migration during lipopolysaccharide-induced peritoneal inflammation but not during Escherichia coli-induced peritonitis.
The Journal of infectious diseases 2006;193(4):522-30.
2006: Marcel Levi; Tom van der Poll; Hugo ten Cate
Tissue factor in infection and severe inflammation.
Seminars in thrombosis and hemostasis 2006;32(1):33-9.
2006: Catharina W Wieland; Sandrine Florquin; Jennie M Pater; Sebastiaan Weijer; Tom van der Poll
CD4+ cells play a limited role in murine lung infection with Mycobacterium kansasii.
American journal of respiratory cell and molecular biology 2006;34(2):167-73.
2006: Koenraad F van der Sluijs; Monique Nijhuis; Johannes Levels; Sandrine Florquin; Andrew L Mellor; Henk M Jansen; Tom van der Poll; René Lutter
Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia.
The Journal of infectious diseases 2006;193(2):214-22.
2006: Rosemarijn Renckens; Joris J T H Roelofs; Sylvia Knapp; Alex F de Vos; Sandrine Florquin; Tom van der Poll
The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii Pneumonia.
The Journal of infectious diseases 2006;193(2):187-95.
2006: Nico A Maris; Sandrine Florquin; Cornelis Van't Veer; Alex F de Vos; Wim A Buurman; Henk M Jansen; Tom van der Poll
Inhalation of beta 2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract.
Respiratory research 2006;7():57.
2006: Jan Van Till; Bas Lamme; T J H van Esch; Tom van der Poll; Thomas M van Gulik; Marja A Boermeester
Surgical therapy attenuates abdominal and extra-abdominal inflammation in experimental peritonitis.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2006;38(2):76-82.
2006: Michael Heesen; Rosemarijn Renckens; Alex F de Vos; Dagmar Kunz; Tom van der Poll
Human endotoxemia induces down-regulation of monocyte CC chemokine receptor 2.
Clinical and vaccine immunology : CVI 2006;13(1):156-9.
2006: Marcel Levi; Evert de Jonge; Tom van der Poll
Plasma and plasma components in the management of disseminated intravascular coagulation.
Best practice & research. Clinical haematology 2006;19(1):127-42.
2006: Sylvia Knapp; Catharina W Wieland; Sandrine Florquin; Ralph Pantophlet; Lenie Dijkshoorn; Ntambua Tshimbalanga; Shizuo Akira; Tom van der Poll
Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia.
American journal of respiratory and critical care medicine 2006;173(1):122-9.
2006: Koenraad F van der Sluijs; Leontine J R van Elden; Monique Nijhuis; Rob Schuurman; Sandrine Florquin; Takao Shimizu; Satoshi Ishii; Henk M Jansen; René Lutter; Tom van der Poll
Involvement of the platelet-activating factor receptor in host defense against Streptococcus pneumoniae during postinfluenza pneumonia.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L194-9.
2005: Sylvia Knapp; Marcus Schultz; Tom van der Poll
Pneumonia models and innate immunity to respiratory bacterial pathogens.
Shock (Augusta, Ga.) 2005;24 Suppl 1():12-8.
2005: Rosemarijn Renckens; Joris J T H Roelofs; Simone A J ter Horst; Cornelis van 't Veer; Stefan R Havik; Sandrine Florquin; Gerry T M Wagenaar; Joost C M Meijers; Tom van der Poll
Absence of thrombin-activatable fibrinolysis inhibitor protects against sepsis-induced liver injury in mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6764-71.
2005: Catharina W Wieland; Sandrine Florquin; Nico A Maris; Kasper Hoebe; Bruce Beutler; Kiyoshi Takeda; Shizuo Akira; Tom van der Poll
The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):6042-9.
2005: Rogier M Determann; Julian L Millo; Sébastien Gibot; Johanna C Korevaar; Margreeth B Vroom; Tom van der Poll; Christopher S Garrard; Marcus Schultz
Serial changes in soluble triggering receptor expressed on myeloid cells in the lung during development of ventilator-associated pneumonia.
Intensive care medicine 2005;31(11):1495-500.
2005: Catharina W Wieland; Sandrine Florquin; Edward D Chan; Jaklien C Leemans; Sebastiaan Weijer; Annelies Verbon; Giamila Fantuzzi; Tom van der Poll
Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice.
International immunology 2005;17(11):1399-408.
2005: Sebastiaan Weijer; Catharina W Wieland; Sandrine Florquin; Tom van der Poll
A thrombomodulin mutation that impairs activated protein C generation results in uncontrolled lung inflammation during murine tuberculosis.
Blood 2005;106(8):2761-8.
2005: Marcel Levi; Tom van der Poll
Two-way interactions between inflammation and coagulation.
Trends in cardiovascular medicine 2005;15(7):254-9.
2005: Jaklien C Leemans; Geurt Stokman; Nike Claessen; Kasper M A Rouschop; Gwendoline J D Teske; Carsten J Kirschning; Shizuo Akira; Tom van der Poll; Jan J Weening; Sandrine Florquin
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney.
The Journal of clinical investigation 2005;115(10):2894-903.
2005: Kasper M A Rouschop; Joris J T H Roelofs; Ajda T Rowshani; Jaklien C Leemans; Tom van der Poll; Ineke J M ten Berge; Jan J Weening; Sandrine Florquin
Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(10):2248-54.
2005: Estella A Koppel; Catharina W Wieland; Venice C M van den Berg; Manja Litjens; Sandrine Florquin; Yvette van Kooyk; Tom van der Poll; Teunis B H Geijtenbeek
Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection.
European journal of immunology 2005;35(10):2962-9.
2005: Nico A Maris; Alex F de Vos; Mark C Dessing; C Arnold Spek; René Lutter; Henk M Jansen; jaring s. van der zee; Paul Bresser; Tom van der Poll
Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers.
American journal of respiratory and critical care medicine 2005;172(7):878-84.
2005: David J van Westerloo; Sylvia Knapp; Cornelis Van't Veer; Wim A Buurman; Alex F de Vos; Sandrine Florquin; Tom van der Poll
Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia.
Critical care medicine 2005;33(8):1770-8.
2005: G Choi; Marcus Schultz; Marcel Levi; Tom van der Poll; Julian L Millo; Christopher S Garrard
Protein C in pneumonia.
Thorax 2005;60(8):705-6.
2005: Judith Branger; Jaklien C Leemans; Sandrine Florquin; Peter Speelman; Douglas T Golenbock; Tom van der Poll
Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection.
Clinical immunology (Orlando, Fla.) 2005;116(2):174-81.
2005: David J van Westerloo; Ida A J Giebelen; Sandrine Florquin; Joost Daalhuisen; Marco J Bruno; Alex F de Vos; Kevin Tracey; Tom van der Poll
The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis.
The Journal of infectious diseases 2005;191(12):2138-48.
2005: Nico A Maris; Alex F de Vos; Paul Bresser; jaring s. van der zee; Joost C M Meijers; H Roger Lijnen; Marcel Levi; Henk M Jansen; Tom van der Poll
Activation of coagulation and inhibition of fibrinolysis in the lung after inhalation of lipopolysaccharide by healthy volunteers.
Thrombosis and haemostasis 2005;93(6):1036-40.
2005: Anita W Rijneveld; Alex F de Vos; Sandrine Florquin; Sjef Verbeek; Tom van der Poll
CD11b limits bacterial outgrowth and dissemination during murine pneumococcal pneumonia.
The Journal of infectious diseases 2005;191(10):1755-60.
2005: Tom van der Poll; Marcel Levi; Jerry A Nick; Edward Abraham
Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans.
American journal of respiratory and critical care medicine 2005;171(10):1125-8.
2005: David J van Westerloo; Sebastiaan Weijer; Marco J Bruno; Alex F de Vos; Cornelis Van't Veer; Tom van der Poll
Toll-like receptor 4 deficiency and acute pancreatitis act similarly in reducing host defense during murine Escherichia coli peritonitis.
Critical care medicine 2005;33(5):1036-43.
2005: Rosemarijn Renckens; Joris J T H Roelofs; Vivian de Waard; Sandrine Florquin; H Roger Lijnen; Peter Carmeliet; Tom van der Poll
The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injury.
Journal of thrombosis and haemostasis : JTH 2005;3(5):1018-25.
2005: Maaike de Fost; Wirongrong Chierakul; Kriangsak Pimda; Arjen M Dondorp; Nicholas J White; Tom van der Poll
Activation of cytotoxic lymphocytes in patients with scrub typhus.
The American journal of tropical medicine and hygiene 2005;72(4):465-7.
2005: David J van Westerloo; Sandrine Florquin; Anita M de Boer; Joost Daalhuisen; Alex F de Vos; Marco J Bruno; Tom van der Poll
Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice.
The American journal of pathology 2005;166(3):721-8.
2005: David van Westerloo; Tom van der Poll
Acute vagotomy activates the cholinergic anti-inflammatory pathway.
American journal of physiology. Heart and circulatory physiology 2005;288(2):H977-8; author reply H978-9.
2005: Sebastiaan Weijer; Sandrine Florquin; Tom van der Poll
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
Shock (Augusta, Ga.) 2005;23(1):54-8.
2005: Jaklien C Leemans; Theo Thepen; Sebastiaan Weijer; Sandrine Florquin; Nico van Rooijen; Jan G J van de Winkel; Tom van der Poll
Macrophages play a dual role during pulmonary tuberculosis in mice.
The Journal of infectious diseases 2005;191(1):65-74.
2004: Sylvia Knapp; Sébastien Gibot; Alex de Vos; Henri H Versteeg; Marco COLONna; Tom van der Poll
Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7131-4.
2004: Catharina W Wieland; Sylvia Knapp; Sandrine Florquin; Alex F de Vos; Kiyoshi Takeda; Shizuo Akira; Douglas T Golenbock; Annelies Verbon; Tom van der Poll
Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2.
American journal of respiratory and critical care medicine 2004;170(12):1367-74.
2004: Judith Branger; Catharina W Wieland; Sandrine Florquin; Nico A Maris; Jennie M Pater; Peter Speelman; Takao Shimizu; Satoshi Ishii; Tom van der Poll
Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable Haemophilus influenzae from their respiratory tract.
Shock (Augusta, Ga.) 2004;22(6):543-7.
2004: Asrat Hailu; Tom van der Poll; Nega Berhe; Piet A Kager
Elevated plasma levels of interferon (IFN)-gamma, IFN-gamma inducing cytokines, and IFN-gamma inducible CXC chemokines in visceral leishmaniasis.
The American journal of tropical medicine and hygiene 2004;71(5):561-7.
2004: G Choi; Marcus Schultz; Jan Van Till; Paul Bresser; jaring s. van der zee; Marja A Boermeester; Marcel Levi; Tom van der Poll
Disturbed alveolar fibrin turnover during pneumonia is restricted to the site of infection.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(5):786-9.
2004: Judith Branger; Sandrine Florquin; Sylvia Knapp; Jaklien C Leemans; Jennie M Pater; Peter Speelman; Douglas T Golenbock; Tom van der Poll
LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia.
International immunology 2004;16(11):1605-11.
2004: Wirongrong Chierakul; Maaike de Fost; Yupin Suputtamongkol; Roongreung Limpaiboon; Arjen M Dondorp; Nicholas J White; Tom van der Poll
Differential expression of interferon-gamma and interferon-gamma-inducing cytokines in Thai patients with scrub typhus or leptospirosis.
Clinical immunology (Orlando, Fla.) 2004;113(2):140-4.
2004: David J van Westerloo; Marcus Schultz; Marco J Bruno; Alex F de Vos; Sandrine Florquin; Tom van der Poll
Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis.
Critical care medicine 2004;32(10):1997-2001.
2004: Koenraad F van der Sluijs; Leontine J R van Elden; Monique Nijhuis; Rob Schuurman; Jennie M Pater; Sandrine Florquin; Michel Goldman; Henk M Jansen; René Lutter; Tom van der Poll
IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7603-9.
2004: Sebastiaan Weijer; Saskia H H F Schoenmakers; Sandrine Florquin; Marcel Levi; George P Vlasuk; William E Rote; Pieter H Reitsma; C Arnold Spek; Tom van der Poll
Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice.
The Journal of infectious diseases 2004;189(12):2308-17.
2004: Marcel Levi; Tom van der Poll; Harry R Büller
Bidirectional relation between inflammation and coagulation.
Circulation 2004;109(22):2698-704.
2004: Nico A Maris; Koenraad F van der Sluijs; Sandrine Florquin; Alex F de Vos; Jennie M Pater; Henk M Jansen; Tom van der Poll
Salmeterol, a beta2-receptor agonist, attenuates lipopolysaccharide-induced lung inflammation in mice.
American journal of physiology. Lung cellular and molecular physiology 2004;286(6):L1122-8.
2004: Marcel Levi; Goda Choi; Ivo Schoots; Marcus Schultz; Tom van der Poll
Beyond sepsis: activated protein C and ischemia-reperfusion injury.
Critical care medicine 2004;32(5 Suppl):S309-12.
2004: Sylvia Knapp; Lars Hareng; Anita W Rijneveld; Paul Bresser; jaring s. van der zee; Sandrine Florquin; Thomas Hartung; Tom van der Poll
Activation of neutrophils and inhibition of the proinflammatory cytokine response by endogenous granulocyte colony-stimulating factor in murine pneumococcal pneumonia.
The Journal of infectious diseases 2004;189(8):1506-15.
2004: Tom van der Poll; Marcel Levi
Mechanisms of action of activated protein C: an evolving story.
Critical care medicine 2004;32(4):1086-7.
2004: Marcel Levi; Tom van der Poll
Coagulation in sepsis: all bugs bite equally.
Critical care (London, England) 2004;8(2):99-100.
2004: Marcus Schultz; Tom van der Poll
Modulation of innate immune responses in the treatment of sepsis and pneumonia.
Current drug targets. Inflammation and allergy 2004;3(1):11-7.
2004: Sylvia Knapp; Catharina W Wieland; Cornelis van 't Veer; Osamu Takeuchi; Shizuo Akira; Sandrine Florquin; Tom van der Poll
Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):3132-8.
2004: Judith Branger; Jaklien C Leemans; Sandrine Florquin; Sebastiaan Weijer; Peter Speelman; Tom van der Poll
Toll-like receptor 4 plays a protective role in pulmonary tuberculosis in mice.
International immunology 2004;16(3):509-16.
2004: Rosemarijn Renckens; Sebastiaan Weijer; Alex F de Vos; Jennie M Pater; Joost C M Meijers; C Erik Hack; Marcel Levi; Tom van der Poll
Inhibition of plasmin activity by tranexamic acid does not influence inflammatory pathways during human endotoxemia.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(3):483-8.
2004: Anita W Rijneveld; Sebastiaan Weijer; Sandrine Florquin; Charles T Esmon; Joost C M Meijers; Peter Speelman; Pieter H Reitsma; Hugo ten Cate; Tom van der Poll
Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
Blood 2004;103(5):1702-9.
2004: Anita W Rijneveld; Sebastiaan Weijer; Sandrine Florquin; Peter Speelman; Takao Shimizu; Satosh Ishii; Tom van der Poll
Improved host defense against pneumococcal pneumonia in platelet-activating factor receptor-deficient mice.
The Journal of infectious diseases 2004;189(4):711-6.
2004: Marcus Schultz; Julian L Millo; Marcel Levi; C E Hack; Gerrit Jan Weverling; Christopher S Garrard; Tom van der Poll
Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia.
Thorax 2004;59(2):130-5.
2004: Judith Branger; Sylvia Knapp; Sebastiaan Weijer; Jaklien C Leemans; Jennie M Pater; Peter Speelman; Sandrine Florquin; Tom van der Poll
Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice.
Infection and immunity 2004;72(2):788-94.
2004: Miguel E Sewnath; Tom van der Poll; Cornelis J F Van Noorden; Fiebo J W Ten Kate; Dirk J Gouma
Cholestatic interleukin-6-deficient mice succumb to endotoxin-induced liver injury and pulmonary inflammation.
American journal of respiratory and critical care medicine 2004;169(3):413-20.
2004: Jaklien C Leemans; Anje A Te Velde; Sandrine Florquin; Roelof J Bennink; Kora de Bruin; René A W van Lier; Tom van der Poll; Jörg Hamann
The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1125-31.
2004: Asrat Hailu; Jennie M Pater; Piet A Kager; Tom van der Poll
Increased expression of HIV co-receptor CXCR4 on CD4+ T-cells in patients with active visceral leishmaniasis.
Scandinavian journal of infectious diseases 2004;36(1):56-8.
2004: Marcel Levi; Evert de Jonge; Tom van der Poll
New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology.
Annals of medicine 2004;36(1):41-9.
2004: Bernt van den Blink; Judith Branger; Sebastiaan Weijer; Abhya Gupta; Sander J H van Deventer; Maikel Peppelenbosch; Tom van der Poll
P38 mitogen activated protein kinase is involved in the downregulation of granulocyte CXC chemokine receptors 1 and 2 during human endotoxemia.
Journal of clinical immunology 2004;24(1):37-41.
2004: Anne-Cornélie J M de Pont; Arno H M Moons; Evert de Jonge; Joost C M Meijers; George P Vlasuk; William E Rote; Harry R Büller; Tom van der Poll; Marcel Levi
Recombinant nematode anticoagulant protein c2, an inhibitor of tissue factor/factor VIIa, attenuates coagulation and the interleukin-10 response in human endotoxemia.
Journal of thrombosis and haemostasis : JTH 2004;2(1):65-70.
2004: Michael Heesen; Dagmar Kunz; Martina Wessiepe; Tom van der Poll; Aeilko H Zwinderman; Brunhilde Blomeke
Rapid genotyping for tumor necrosis factor-alpha (TNF-alpha)-863C/A promoter polymorphism that determines TNF-alpha response.
Clinical chemistry 2004;50(1):226-8.
2004: Julian L Millo; Marcus Schultz; Conrad Williams; Gerrit Jan Weverling; Timothy Ringrose; Carolyn I Mackinlay; Tom van der Poll; Christopher S Garrard
Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia.
Intensive care medicine 2004;30(1):68-74.
2003: Petra J G Zwijnenburg; Henrica M A de Bie; John J Roord; Tom van der Poll; A Marceline van Furth
Chemotactic activity of CXCL5 in cerebrospinal fluid of children with bacterial meningitis.
Journal of neuroimmunology 2003;145(1-2):148-53.
2003: Sylvia Knapp; Alex F de Vos; Sandrine Florquin; Douglas T Golenbock; Tom van der Poll
Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice.
Infection and immunity 2003;71(12):6747-53.
2003: Koenraad F van der Sluijs; Leontine J R van Elden; Monique Nijhuis; Rob Schuurman; Sandrine Florquin; Henk M Jansen; René Lutter; Tom van der Poll
Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus.
Immunology letters 2003;89(2-3):201-6.
2003: Anita W Rijneveld; Sandrine Florquin; Peter Speelman; Carl K Edwards; Charles A Dinarello; Tom van der Poll
Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia.
European cytokine network 2003;14(4):242-5.
2003: Sebastiaan Weijer; Miguel E Sewnath; Alex F de Vos; Sandrine Florquin; Koen van der Sluis; Dirk J Gouma; Kiyoshi Takeda; Shizuo Akira; Tom van der Poll
Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis.
Infection and immunity 2003;71(10):5488-97.
2003: Jaklien C Leemans; Mirjam Heikens; Kok P M van Kessel; Sandrine Florquin; Tom van der Poll
Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice.
Clinical and diagnostic laboratory immunology 2003;10(5):950-3.
2003: Marcel Levi; Evert de Jonge; Tom van der Poll
Sepsis and disseminated intravascular coagulation.
Journal of thrombosis and thrombolysis 2003;16(1-2):43-7.
2003: Sebastiaan Weijer; Jaklien C Leemans; Sandrine Florquin; Takao Shimizu; Satoshi Ishii; Tom van der Poll
Host response of platelet-activating factor receptor-deficient mice during pulmonary tuberculosis.
Immunology 2003;109(4):552-6.
2003: Anita W Rijneveld; Sandrine Florquin; Paul Bresser; Marcel Levi; Vivian de Waard; Roger Lijnen; jaring s. van der zee; Peter Speelman; Peter Carmeliet; Tom van der Poll
Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia.
Blood 2003;102(3):934-9.
2003: Anita W Rijneveld; Sandrine Florquin; Thomas Hartung; Peter Speelman; Tom van der Poll
Anti-tumor necrosis factor antibody impairs the therapeutic effect of ceftriaxone in murine pneumococcal pneumonia.
The Journal of infectious diseases 2003;188(2):282-5.
2003: Dariusz P Olszyna; Annelies Verbon; John P Pribble; Terence Turner; Tim Axtelle; Sander J H van Deventer; Tom van der Poll
Effect of IC14, an anti-CD14 antibody, on plasma and cell-associated chemokines during human endotoxemia.
European cytokine network 2003;14(3):158-62.
2003: Marcel Levi; Janine Dörffler-Melly; Pieter H Reitsma; Harry Buller; Sandrine Florquin; Tom van der Poll; Peter Carmeliet
Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice.
Blood 2003;101(12):4823-7.
2003: Judith Branger; Bernt van den Blink; Sebastiaan Weijer; Abhya Gupta; Sander J H van Deventer; C Erik Hack; Maikel Peppelenbosch; Tom van der Poll
Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia.
Blood 2003;101(11):4446-8.
2003: Pieter H Reitsma; Judith Branger; Bernt van den Blink; Sebastiaan Weijer; Tom van der Poll; Joost C M Meijers
Procoagulant protein levels are differentially increased during human endotoxemia.
Journal of thrombosis and haemostasis : JTH 2003;1(5):1019-23.
2003: Petra J G Zwijnenburg; Tom van der Poll; Sandrine Florquin; Shizuo Akira; Kiyoshi Takeda; John J Roord; A Marceline van Furth
Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis.
Journal of neuroimmunology 2003;138(1-2):31-7.
2003: Evert de Jonge; Philip W Friederich; George P Vlasuk; William E Rote; Margaretha B Vroom; Marcel Levi; Tom van der Poll
Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects.
Clinical and diagnostic laboratory immunology 2003;10(3):495-7.
2003: Patrick Stordeur; Ling Zhou; Baudouin Byl; Fabian Brohet; Wivine Burny; Donat de Groote; Tom van der Poll; Michel Goldman
Immune monitoring in whole blood using real-time PCR.
Journal of immunological methods 2003;276(1-2):69-77.
2003: Petra J G Zwijnenburg; Tom van der Poll; Sandrine Florquin; John J Roord; A Marceline van Furth
IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(9):4724-30.
2003: Marcus J Schultz; Marcel Levi; Tom van der Poll
Anticoagulant therapy for acute lung injury or pneumonia.
Current drug targets 2003;4(4):315-21.
2003: Marcel Levi; Marcus Schultz; Anita W Rijneveld; Tom van der Poll
Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia.
Critical care medicine 2003;31(4 Suppl):S238-42.
2003: Petra J G Zwijnenburg; Tom van der Poll; Sandrine Florquin; John J Roord; A Marceline van Furth
Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
Infection and immunity 2003;71(4):2276-9.
2003: Marcus Schultz; Sylvia Knapp; Sandrine Florquin; Jennie M Pater; Kiyoshi Takeda; Shizuo Akira; Tom van der Poll
Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa.
Infection and immunity 2003;71(4):1630-4.
2003: C Arnold Spek; Annelies Verbon; Hella Aberson; John P Pribble; Cathal J McElgunn; Terence Turner; Tim Axtelle; Jan Schouten; Tom van der Poll; Pieter H Reitsma
Treatment with an anti-CD14 monoclonal antibody delays and inhibits lipopolysaccharide-induced gene expression in humans in vivo.
Journal of clinical immunology 2003;23(2):132-40.
2003: Maaike de Fost; Rudy A Hartskeerl; Martijn R Groenendijk; Tom van der Poll
Interleukin 12 in part regulates gamma interferon release in human whole blood stimulated with Leptospira interrogans.
Clinical and diagnostic laboratory immunology 2003;10(2):332-5.
2003: Jaklien C Leemans; Sandrine Florquin; Mirjam Heikens; Steven T Pals; Ronald van der Neut; Tom van der Poll
CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis.
The Journal of clinical investigation 2003;111(5):681-9.
2003: David J van Westerloo; N A Maris; Marco J Bruno; Tom van der Poll
Caerulein induced pancreatitis.
Gut 2003;52(3):452-3; author reply 453.
2003: Sylvia Knapp; Jaklien C Leemans; Sandrine Florquin; Judith Branger; Nico A Maris; Jennie M Pater; Nico van Rooijen; Tom van der Poll
Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia.
American journal of respiratory and critical care medicine 2003;167(2):171-9.
2003: Petra J G Zwijnenburg; Machteld M J Polfliet; Sandrine Florquin; Timo K van den Berg; Christine D Dijkstra; Sander J H van Deventer; John J Roord; Tom van der Poll; A Marceline van Furth
CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats.
Immunology letters 2003;85(1):1-4.
2003: Kamilla D Lettinga; Sebastiaan Weijer; Peter Speelman; Jan M Prins; Tom van der Poll; Annelies Verbon
Reduced interferon-gamma release in patients recovered from Legionnaires' disease.
Thorax 2003;58(1):63-7.
2003: Annelies Verbon; Joost C M Meijers; C Arnold Spek; C Erik Hack; John P Pribble; Terence Turner; Pascale E P Dekkers; Tim Axtelle; Marcel Levi; Sander J H van Deventer; Pieter H Reitsma; Tom van der Poll
Effects of IC14, an anti-CD14 antibody, on coagulation and fibrinolysis during low-grade endotoxemia in humans.
The Journal of infectious diseases 2003;187(1):55-61.
2002: Sebastiaan Weijer; Fanny N Lauw; Judith Branger; Bernt van den Blink; Tom van der Poll
Diminished interferon-gamma production and responsiveness after endotoxin administration to healthy humans.
The Journal of infectious diseases 2002;186(12):1748-53.
2002: Marcel Levi; Evert de Jonge; Tom van der Poll
Therapeutic intervention in disseminated intravascular coagulation: have we made any progress in the last millennium?
Blood reviews 2002;16 Suppl 1():S29-34.
2002: Miguel E Sewnath; Tom van der Poll; Cornelis J F Van Noorden; Fiebo J W Ten Kate; Dirk J Gouma
Endogenous interferon gamma protects against cholestatic liver injury in mice.
Hepatology (Baltimore, Md.) 2002;36(6):1466-77.
2002: Annelies Verbon; Jaklien C Leemans; Sebastiaan Weijer; Sandrine Florquin; Tom van der Poll
Mice lacking the multidrug resistance protein 1 have a transiently impaired immune response during tuberculosis.
Clinical and experimental immunology 2002;130(1):32-6.
2002: Marcel Levi; Evert de Jonge; Tom van der Poll
Recombinant human activated protein C (Xigris).
International journal of clinical practice 2002;56(7):542-5.
2002: Kamilla D Lettinga; Sandrine Florquin; Peter Speelman; Ruud J Van Ketel; Tom van der Poll; Annelies Verbon
Toll-like receptor 4 is not involved in host defense against pulmonary Legionella pneumophila infection in a mouse model.
The Journal of infectious diseases 2002;186(4):570-3.
2002: Jaklien C Leemans; Margriet J Vervoordeldonk; Sandrine Florquin; Kok P M van Kessel; Tom van der Poll
Differential role of interleukin-6 in lung inflammation induced by lipoteichoic acid and peptidoglycan from Staphylococcus aureus.
American journal of respiratory and critical care medicine 2002;165(10):1445-50.
2002: Marcel Levi; Hugo ten Cate; Tom van der Poll
Endothelium: interface between coagulation and inflammation.
Critical care medicine 2002;30(5 Suppl):S220-4.
2002: Judith Branger; Bernt van den Blink; Sebastiaan Weijer; Jeffrey Madwed; Carina L Bos; Abhya Gupta; Chan-Loi Yong; Stephen H Polmar; Dariusz P Olszyna; C Erik Hack; Sander J H van Deventer; Maikel Peppelenbosch; Tom van der Poll
Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4070-7.
2002: Nicole P Juffermans; Sebastiaan Weijer; Annelies Verbon; Peter Speelman; Tom van der Poll
Expression of human immunodeficiency virus coreceptors CXC chemokine receptor 4 and CC chemokine receptor 5 on monocytes is down-regulated during human endotoxemia.
The Journal of infectious diseases 2002;185(7):986-9.
2002: Anita W Rijneveld; Marcel Levi; Sandrine Florquin; Peter Speelman; Peter Carmeliet; Tom van der Poll
Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3507-11.
2002: Marcus Schultz; Anita W Rijneveld; Sandrine Florquin; Carl K Edwards; Charles A Dinarello; Tom van der Poll
Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia.
American journal of physiology. Lung cellular and molecular physiology 2002;282(2):L285-90.
2002: Marcus Schultz; Tom van der Poll
Animal and human models for sepsis.
Annals of medicine 2002;34(7-8):573-81.
2002: Sylvia Knapp; Judith Branger; Tom van der Poll
Advances in research of the inflammatory response: the importance of toll-like receptors.
Wiener medizinische Wochenschrift (1946) 2002;152(21-22):552-4.
2002: Marcus Schultz; Tom van der Poll
Modulation of pulmonary innate immunity during bacterial infection: animal studies.
Archivum immunologiae et therapiae experimentalis 2002;50(3):159-67.
2002: Nicole P Juffermans; Annelies Verbon; Tom van der Poll
Diabetes insipidus as a complication of cryptococcal meningitis in an HIV-infected patient.
Scandinavian journal of infectious diseases 2002;34(5):397-8.
2002: Miguel E Sewnath; Tom van der Poll; Fiebo J W Ten Kate; Cornelis J F Van Noorden; Dirk J Gouma
Interleukin-1 receptor type I gene-deficient bile duct-ligated mice are partially protected against endotoxin.
Hepatology (Baltimore, Md.) 2002;35(1):149-58.
2002: Anita W Rijneveld; Germie van den Dobbelsteen; Sandrine Florquin; Theodore J Standiford; Peter Speelman; Loek van Alphen; Tom van der Poll
Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice.
The Journal of infectious diseases 2002;185(1):123-6.
2002: Anita W Rijneveld; Fanny N Lauw; Marcus Schultz; Sandrine Florquin; Anje A Te Velde; Peter Speelman; Sander J H van Deventer; Tom van der Poll
The role of interferon-gamma in murine pneumococcal pneumonia.
The Journal of infectious diseases 2002;185(1):91-7.
2002: Fanny N Lauw; Judith Branger; Sandrine Florquin; Peter Speelman; Sander J H van Deventer; Shizuo Akira; Tom van der Poll
IL-18 improves the early antimicrobial host response to pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):372-8.
2002: Nicole P Juffermans; Jaklien C Leemans; Sandrine Florquin; Annelies Verbon; Arend H J Kolk; Peter Speelman; Sander J H van Deventer; Tom van der Poll
CpG oligodeoxynucleotides enhance host defense during murine tuberculosis.
Infection and immunity 2002;70(1):147-52.
2001: Henk-Jan Guchelaar; Marcus Schultz; Tom van der Poll; R P Koopmans
Pharmacokinetic-pharmacodynamic modeling of the inhibitory effect of erythromycin on tumour necrosis factor-alpha and interleukin-6 production.
Fundamental & clinical pharmacology 2001;15(6):419-24.
2001: Evert de Jonge; Tom van der Poll; Jozef Kesecioglu; Marcel Levi
Anticoagulant factor concentrates in disseminated intravascular coagulation: rationale for use and clinical experience.
Seminars in thrombosis and hemostasis 2001;27(6):667-74.
2001: Tom van der Poll; Evert de Jonge; Marcel Levi
Regulatory role of cytokines in disseminated intravascular coagulation.
Seminars in thrombosis and hemostasis 2001;27(6):639-51.
2001: Marcel Levi; Evert de Jonge; Tom van der Poll; Hugo ten Cate
Advances in the understanding of the pathogenetic pathways of disseminated intravascular coagulation result in more insight in the clinical picture and better management strategies.
Seminars in thrombosis and hemostasis 2001;27(6):569-75.
2001: Bernt van den Blink; Judith Branger; Sebastiaan Weijer; S H Deventer; Tom van der Poll; Maikel Peppelenbosch
Human endotoxemia activates p38 MAP kinase and p42/44 MAP kinase, but not c-Jun N-terminal kinase.
Molecular medicine (Cambridge, Mass.) 2001;7(11):755-60.
2001: Anita W Rijneveld; Sandrine Florquin; Judith Branger; Peter Speelman; Sander J H van Deventer; Tom van der Poll
TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5240-6.
2001: Machteld M J Polfliet; Petra J G Zwijnenburg; A Marceline van Furth; Tom van der Poll; Ed A Döpp; Chantal Renardel de Lavalette; Esther van Kesteren-Hendrikx; Nico van Rooijen; Christine D Dijkstra; Timo K van den Berg
Meningeal and perivascular macrophages of the central nervous system play a protective role during bacterial meningitis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4644-50.
2001: Tom van der Poll
Immunotherapy of sepsis.
The Lancet infectious diseases 2001;1(3):165-74.
2001: Dariusz P Olszyna; Hester Vermeulen; A H Baan; Peter Speelman; Sander J H van Deventer; Dirk J Gouma; Tom van der Poll
Urine interleukin-8 is a marker for urinary tract infection in postoperative patients.
Infection 2001;29(5):274-7.
2001: Marcus Schultz; Anita W Rijneveld; Sandrine Florquin; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Impairment of host defence by exotoxin A in Pseudomonas aeruginosa pneumonia in mice.
Journal of medical microbiology 2001;50(9):822-7.
2001: Fanny N Lauw; Sandrine Florquin; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Role of endogenous interleukin-12 in immune response to staphylococcal enterotoxin B in mice.
Infection and immunity 2001;69(9):5949-52.
2001: Marcus Schultz; Peter Speelman; Tom van der Poll
Erythromycin inhibits Pseudomonas aeruginosa-induced tumour necrosis factor-alpha production in human whole blood.
The Journal of antimicrobial chemotherapy 2001;48(2):275-8.
2001: Dariusz P Olszyna; Dasja Pajkrt; Sander J H van Deventer; Tom van der Poll
Effect of interleukin 10 on the release of the CXC chemokines growth related oncogene GRO-alpha and epithelial cell-derived neutrophil activating peptide (ENA)-78 during human endotoxemia.
Immunology letters 2001;78(1):41-4.
2001: Nicole P Juffermans; Pascale E P Dekkers; Annelies Verbon; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Concurrent upregulation of urokinase plasminogen activator receptor and CD11b during tuberculosis and experimental endotoxemia.
Infection and immunity 2001;69(8):5182-5.
2001: Dariusz P Olszyna; Sandrine Florquin; Miguel E Sewnath; Judith Branger; Peter Speelman; Sander J H van Deventer; R M Strieter; Tom van der Poll
CXC chemokine receptor 2 contributes to host defense in murine urinary tract infection.
The Journal of infectious diseases 2001;184(3):301-7.
2001: Marcel Levi; Evert de Jonge; Tom van der Poll
Rationale for restoration of physiological anticoagulant pathways in patients with sepsis and disseminated intravascular coagulation.
Critical care medicine 2001;29(7 Suppl):S90-4.
2001: Evert de Jonge; Pascale E P Dekkers; A A Creasey; C Erik Hack; S K Paulson; A Karim; Jozef Kesecioglu; Marcel Levi; Sander J H van Deventer; Tom van der Poll
Tissue factor pathway inhibitor does not influence inflammatory pathways during human endotoxemia.
The Journal of infectious diseases 2001;183(12):1815-8.
2001: Sandrine Florquin; José G Van Den Berg; Dariusz P Olszyna; Nike Claessen; S M Opal; Jan J Weening; Tom van der Poll
Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia.
Kidney international 2001;59(6):2054-61.
2001: Miguel E Sewnath; Dariusz P Olszyna; Rakesh S Birjmohun; Fiebo J W Ten Kate; Dirk J Gouma; Tom van der Poll
IL-10-deficient mice demonstrate multiple organ failure and increased mortality during Escherichia coli peritonitis despite an accelerated bacterial clearance.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6323-31.
2001: Nicole P Juffermans; Annelies Verbon; Marcus Schultz; C Erik Hack; Sander J H van Deventer; Peter Speelman; Tom van der Poll
Thalidomide inhibits granulocyte responses in healthy humans after ex vivo stimulation with bacterial antigens.
Antimicrobial agents and chemotherapy 2001;45(5):1547-9.
2001: Jaklien C Leemans; Nicole P Juffermans; Sandrine Florquin; Nico van Rooijen; Margriet J Vervoordeldonk; Annelies Verbon; Sander J H van Deventer; Tom van der Poll
Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4604-11.
2001: Dariusz P Olszyna; Evert de Jonge; Pascale E P Dekkers; Sander J H van Deventer; Tom van der Poll
Induction of cell-associated chemokines after endotoxin administration to healthy humans.
Infection and immunity 2001;69(4):2736-8.
2001: Petra J G Zwijnenburg; Tom van der Poll; Sandrine Florquin; Sander J H van Deventer; John J Roord; A Marceline van Furth
Experimental pneumococcal meningitis in mice: a model of intranasal infection.
The Journal of infectious diseases 2001;183(7):1143-6.
2001: Marcus Schultz; J Wijnholds; Maikel Peppelenbosch; Margriet J Vervoordeldonk; Peter Speelman; Sander J H van Deventer; P Borst; Tom van der Poll
Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):4059-64.
2001: Marcus Schultz; Anita W Rijneveld; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Endogenous interferon-gamma impairs bacterial clearance from lungs during Pseudomonas aeruginosa pneumonia.
European cytokine network 2001;12(1):39-44.
2001: Annelies Verbon; Pascale E P Dekkers; Tessa ten Hove; C Erik Hack; John P Pribble; Terence Turner; Sonia Souza; Tim Axtelle; Frans J Hoek; Sander J H van Deventer; Tom van der Poll
IC14, an anti-CD14 antibody, inhibits endotoxin-mediated symptoms and inflammatory responses in humans.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3599-605.
2001: Fanny N Lauw; J T M van der Meer; Jesse de Metz; Sven A Danner; Tom van der Poll
No beneficial effect of interferon-gamma treatment in 2 human immunodeficiency virus-infected patients with Mycobacterium avium complex infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(4):e81-2.
2001: Nicole P Juffermans; Peter Speelman; Annelies Verbon; J Veenstra; C Jie; Sander J H van Deventer; Tom van der Poll
Patients with active tuberculosis have increased expression of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(4):650-2.
2001: Bernt van den Blink; Nicole P Juffermans; Tessa ten Hove; Marcus Schultz; Sander J H van Deventer; Tom van der Poll; Maikel Peppelenbosch
p38 mitogen-activated protein kinase inhibition increases cytokine release by macrophages in vitro and during infection in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):582-7.
2000: JJ Boelens; Tom van der Poll; Sebastian A J Zaat; Jean-Luc Murk; Jan J Weening; Jacob Dankert
Interleukin-1 receptor type I gene-deficient mice are less susceptible to Staphylococcus epidermidis biomaterial-associated infection than are wild-type mice.
Infection and immunity 2000;68(12):6924-31.
2000: Dariusz P Olszyna; S M Opal; Jan M Prins; DL Horn; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Chemotactic activity of CXC chemokines interleukin-8, growth-related oncogene-alpha, and epithelial cell-derived neutrophil-activating protein-78 in urine of patients with urosepsis.
The Journal of infectious diseases 2000;182(6):1731-7.
2000: Marcus Schultz; Peter Speelman; Sebastian A J Zaat; C E Hack; Sander J H van Deventer; Tom van der Poll
The effect of pseudomonas exotoxin A on cytokine production in whole blood exposed to Pseudomonas aeruginosa.
FEMS immunology and medical microbiology 2000;29(3):227-32.
2000: Nicole P Juffermans; William A Paxton; Pascale E P Dekkers; Annelies Verbon; Evert de Jonge; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Up-regulation of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells during human endotoxemia and after stimulation with (myco)bacterial antigens: the role of cytokines.
Blood 2000;96(8):2649-54.
2000: Marcus Schultz; Dariusz P Olszyna; Evert de Jonge; Annelies Verbon; Sander J H van Deventer; Tom van der Poll
Reduced ex vivo chemokine production by polymorphonuclear cells after in vivo exposure of normal humans to endotoxin.
The Journal of infectious diseases 2000;182(4):1264-7.
2000: Marcel Levi; Evert de Jonge; Tom van der Poll; Hugo ten Cate
Novel approaches to the management of disseminated intravascular coagulation.
Critical care medicine 2000;28(9 Suppl):S20-4.
2000: Annelies Verbon; Nicole P Juffermans; Peter Speelman; Sander J H van Deventer; I J ten Berge; Henk-Jan Guchelaar; Tom van der Poll
A single oral dose of thalidomide enhances the capacity of lymphocytes to secrete gamma interferon in healthy humans.
Antimicrobial agents and chemotherapy 2000;44(9):2286-90.
2000: Nicole P Juffermans; Sandrine Florquin; Luisa Camoglio; Annelies Verbon; Arend H J Kolk; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis.
The Journal of infectious diseases 2000;182(3):902-8.
2000: Nicole P Juffermans; Pascale E P Dekkers; Maikel Peppelenbosch; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Expression of the chemokine receptors CXCR1 and CXCR2 on granulocytes in human endotoxemia and tuberculosis: involvement of the p38 mitogen-activated protein kinase pathway.
The Journal of infectious diseases 2000;182(3):888-94.
2000: Fanny N Lauw; Dasja Pajkrt; C Erik Hack; M Kurimoto; Sander J H van Deventer; Tom van der Poll
Proinflammatory effects of IL-10 during human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2783-9.
2000: Nicole P Juffermans; Annelies Verbon; John Belisle; Preston J Hill; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Mycobacterial lipoarabinomannan induces an inflammatory response in the mouse lung. A role for interleukin-1.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):486-9.
2000: Marcus Schultz; Peter Speelman; C Erik Hack; Wim A Buurman; Sander J H van Deventer; Tom van der Poll
Intravenous infusion of erythromycin inhibits CXC chemokine production, but augments neutrophil degranulation in whole blood stimulated with Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2000;46(2):235-40.
2000: Rendrik F Franco; Evert de Jonge; Pascale E P Dekkers; Janneke J Timmerman; C Arnold Spek; Sander J H van Deventer; P van Deursen; L van Kerkhoff; B van Gemen; Hugo ten Cate; Tom van der Poll; Pieter H Reitsma
The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation.
Blood 2000;96(2):554-9.
2000: Fanny N Lauw; AJ Simpson; C Erik Hack; Jan M Prins; Angela M Wolbink; Sander J H van Deventer; W Chaowagul; Nicholas J White; Tom van der Poll
Soluble granzymes are released during human endotoxemia and in patients with severe infection due to gram-negative bacteria.
The Journal of infectious diseases 2000;182(1):206-13.
2000: Fanny N Lauw; AJ Simpson; Jan M Prins; Sander J H van Deventer; W Chaowagul; Nicholas J White; Tom van der Poll
The CXC chemokines gamma interferon (IFN-gamma)-inducible protein 10 and monokine induced by IFN-gamma are released during severe melioidosis.
Infection and immunity 2000;68(7):3888-93.
2000: Pascale E P Dekkers; Nicole P Juffermans; T t Hove; Evert de Jonge; Sander J H van Deventer; Tom van der Poll
Granulocyte colony-stimulating factor receptors on granulocytes are down-regulated after endotoxin administration to healthy humans.
The Journal of infectious diseases 2000;181(6):2067-70.
2000: Nicole P Juffermans; Annelies Verbon; Dariusz P Olszyna; Sander J H van Deventer; Peter Speelman; Tom van der Poll
Thalidomide suppresses Up-regulation of human immunodeficiency virus coreceptors CXCR4 and CCR5 on CD4+ T cells in humans.
The Journal of infectious diseases 2000;181(5):1813-6.
2000: Pascale E P Dekkers; Tessa ten Hove; Fanny N Lauw; HR Koene; P Lumley; Sander J H van Deventer; Tom van der Poll
The metalloproteinase inhibitor GI5402 inhibits endotoxin-induced soluble CD27 and CD16 release in healthy humans.
Infection and immunity 2000;68(5):3036-9.
2000: JJ Boelens; Jacob Dankert; Jean-Luc Murk; Jan J Weening; Tom van der Poll; K P Dingemans; L Koole; J D Laman; Sebastian A J Zaat
Biomaterial-associated persistence of Staphylococcus epidermidis in pericatheter macrophages.
The Journal of infectious diseases 2000;181(4):1337-49.
2000: Pascale E P Dekkers; Tessa ten Hove; Anje A Te Velde; Sander J H van Deventer; Tom van der Poll
Upregulation of monocyte urokinase plasminogen activator receptor during human endotoxemia.
Infection and immunity 2000;68(4):2156-60.
2000: JJ Boelens; Tom van der Poll; Jacob Dankert; Sebastian A J Zaat
Interferon-gamma protects against biomaterial-associated Staphylococcus epidermidis infection in mice.
The Journal of infectious diseases 2000;181(3):1167-71.
2000: Pascale E P Dekkers; Nicole P Juffermans; Tessa ten Hove; Evert de Jonge; Sander J H van Deventer; Tom van der Poll
Endotoxin down-regulates monocyte and granulocyte interleukin-6 receptors without influencing gp130 expression in humans.
The Journal of infectious diseases 2000;181(3):1055-61.
2000: JJ Boelens; Sebastian A J Zaat; Jean-Luc Murk; Jan J Weening; Tom van der Poll; Jacob Dankert
Enhanced susceptibility to subcutaneous abscess formation and persistent infection around catheters is associated with sustained interleukin-1beta levels.
Infection and immunity 2000;68(3):1692-5.
2000: Fanny N Lauw; Tessa ten Hove; Pascale E P Dekkers; Evert de Jonge; Sander J H van Deventer; Tom van der Poll
Reduced Th1, but not Th2, cytokine production by lymphocytes after in vivo exposure of healthy subjects to endotoxin.
Infection and immunity 2000;68(3):1014-8.
2000: Evert de Jonge; Pascale E P Dekkers; A A Creasey; C Erik Hack; S K Paulson; A Karim; Jozef Kesecioglu; Marcel Levi; Sander J H van Deventer; Tom van der Poll
Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia.
Blood 2000;95(4):1124-9.
2000: Dariusz P Olszyna; Dasja Pajkrt; Fanny N Lauw; Sander J H van Deventer; Tom van der Poll
Interleukin 10 inhibits the release of CC chemokines during human endotoxemia.
The Journal of infectious diseases 2000;181(2):613-20.
2000: Roelien H Enting; NA Foudraine; Joep M A Lange; Suzanne Jurriaans; Tom van der Poll; Gerrit Jan Weverling; Peter Portegies
Cerebrospinal fluid beta2-microglobulin, monocyte chemotactic protein-1, and soluble tumour necrosis factor alpha receptors before and after treatment with lamivudine plus zidovudine or stavudine.
Journal of neuroimmunology 2000;102(2):216-21.
1999: Fanny N Lauw; AJ Simpson; Jan M Prins; M D Smith; M Kurimoto; Sander J H van Deventer; Peter Speelman; W Chaowagul; Nicholas J White; Tom van der Poll
Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis.
The Journal of infectious diseases 1999;180(6):1878-85.
1999: Dariusz P Olszyna; Jan M Prins; Pascale E P Dekkers; Evert de Jonge; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Sequential measurements of chemokines in urosepsis and experimental endotoxemia.
Journal of clinical immunology 1999;19(6):399-405.
1999: Pascale E P Dekkers; Fanny N Lauw; Tessa ten Hove; Anje A Te Velde; P Lumley; D Becherer; Sander J H van Deventer; Tom van der Poll
The effect of a metalloproteinase inhibitor (GI5402) on tumor necrosis factor-alpha (TNF-alpha) and TNF-alpha receptors during human endotoxemia.
Blood 1999;94(7):2252-8.
1999: Pascale E P Dekkers; Marcel Levi; Sander J H van Deventer; Tom van der Poll
Divergent roles of tumor necrosis factor and platelet-activating factor in endotoxin-induced release of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta in chimpanzees.
Infection and immunity 1999;67(10):5480-2.
1999: Marcel Levi; Evert de Jonge; Tom van der Poll; Hugo ten Cate
Disseminated intravascular coagulation.
Thrombosis and haemostasis 1999;82(2):695-705.
1999: Nicole P Juffermans; Annelies Verbon; Sander J H van Deventer; H van Deutekom; John Belisle; M E Ellis; Peter Speelman; Tom van der Poll
Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan.
Infection and immunity 1999;67(8):4295-7.
1999: Fanny N Lauw; Anje A Te Velde; Pascale E P Dekkers; Peter Speelman; johannes aerts; C Erik Hack; Sander J H van Deventer; Tom van der Poll
Activation of mononuclear cells by interleukin-12: an in vivo study in chimpanzees.
Journal of clinical immunology 1999;19(4):231-8.
1999: Tom van der Poll; Sander J H van Deventer
Cytokines and anticytokines in the pathogenesis of sepsis.
Infectious disease clinics of North America 1999;13(2):413-26, ix.
1999: Fanny N Lauw; Pascale E P Dekkers; Anje A Te Velde; Peter Speelman; Marcel Levi; M Kurimoto; C Erik Hack; Sander J H van Deventer; Tom van der Poll
Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees.
The Journal of infectious diseases 1999;179(3):646-52.
1999: Annelies Verbon; Nicole P Juffermans; Sander J H van Deventer; Peter Speelman; H van Deutekom; Tom van der Poll
Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment.
Clinical and experimental immunology 1999;115(1):110-3.
1998: Nicole P Juffermans; Annelies Verbon; Sander J H van Deventer; Wim A Buurman; H van Deutekom; Peter Speelman; Tom van der Poll
Serum concentrations of lipopolysaccharide activity-modulating proteins during tuberculosis.
The Journal of infectious diseases 1998;178(6):1839-42.
1998: Lucienne C Lemaire; Tom van der Poll; J J B van Lanschot; Erik Endert; Wim A Buurman; Sander J H van Deventer; Dirk J Gouma
Minimally invasive surgery induces endotoxin-tolerance in the absence of detectable endotoxemia.
Journal of clinical immunology 1998;18(6):414-20.
1998: Lucienne C Lemaire; J J B van Lanschot; Tom van der Poll; Wim A Buurman; Sander J H van Deventer; Dirk J Gouma
Lymph of patients with a systemic inflammatory response syndrome inhibits lipopolysaccharide-induced cytokine production.
The Journal of infectious diseases 1998;178(3):883-6.
1998: Dariusz P Olszyna; Jan M Prins; B Buis; Sander J H van Deventer; Peter Speelman; Tom van der Poll
Levels of inhibitors of tumor necrosis factor alpha and interleukin 1beta in urine and sera of patients with urosepsis.
Infection and immunity 1998;66(8):3527-34.
1998: Marcus Schultz; Peter Speelman; Sebastian A J Zaat; Sander J H van Deventer; Tom van der Poll
Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood.
Antimicrobial agents and chemotherapy 1998;42(7):1605-9.
1998: Marcel Levi; Tom van der Poll; Hugo ten Cate; B Kuipers; Bart J Biemond; Henk M Jansen; JW ten Cate
Differential effects of anti-cytokine treatment on bronchoalveolar hemostasis in endotoxemic chimpanzees.
American journal of respiratory and critical care medicine 1998;158(1):92-8.
1998: Mark I van Berge Henegouwen; Tom van der Poll; S J van Deventer; Dirk J Gouma
Peritoneal cytokine release after elective gastrointestinal surgery and postoperative complications.
American journal of surgery 1998;175(4):311-6.
1998: Nicole P Juffermans; Annelies Verbon; Sander J H van Deventer; H van Deutekom; Peter Speelman; Tom van der Poll
Tumor necrosis factor and interleukin-1 inhibitors as markers of disease activity of tuberculosis.
American journal of respiratory and critical care medicine 1998;157(4 Pt 1):1328-31.
1998: Tom van der Poll; Sander J H van Deventer
The role of interleukin 6 in endotoxin-induced inflammatory responses.
Progress in clinical and biological research 1998;397():365-77.
1997: Dasja Pajkrt; A Manten; Tom van der Poll; MM Tiel-van Buul; J Jansen; J Wouter ten Cate; Sander J H van Deventer
Modulation of cytokine release and neutrophil function by granulocyte colony-stimulating factor during endotoxemia in humans.
Blood 1997;90(4):1415-24.
1997: JW ten Cate; Tom van der Poll; Marcel Levi; Hugo ten Cate; Sander J H van Deventer
Cytokines: triggers of clinical thrombotic disease.
Thrombosis and haemostasis 1997;78(1):415-9.
1997: Dasja Pajkrt; Tom van der Poll; Marcel Levi; David L Cutler; Melton Affrime; A van den Ende; JW ten Cate; Sander J H van Deventer
Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia.
Blood 1997;89(8):2701-5.
1997: Dasja Pajkrt; Luisa Camoglio; M C Tiel-van Buul; Kora de Bruin; David L Cutler; Melton Affrime; G Rikken; Tom van der Poll; JW ten Cate; Sander J H van Deventer
Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3971-7.
1997: Dasja Pajkrt; PG Lerch; Tom van der Poll; Marcel Levi; M Illi; JE Doran; B Arnet; A van den Ende; JW ten Cate; Sander J H van Deventer
Differential effects of reconstituted high-density lipoprotein on coagulation, fibrinolysis and platelet activation during human endotoxemia.
Thrombosis and haemostasis 1997;77(2):303-7.
1997: Marcel Levi; Tom van der Poll; Hugo ten Cate; Sander J H van Deventer
The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia.
European journal of clinical investigation 1997;27(1):3-9.
1996: J M Stouthard; Marcel Levi; C Erik Hack; C H Veenhof; H A Romijn; Hans P Sauerwein; Tom van der Poll
Interleukin-6 stimulates coagulation, not fibrinolysis, in humans.
Thrombosis and haemostasis 1996;76(5):738-42.
1996: Dasja Pajkrt; JE Doran; F Koster; PG Lerch; B Arnet; Tom van der Poll; JW ten Cate; Sander J H van Deventer
Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia.
The Journal of experimental medicine 1996;184(5):1601-8.
1996: M A von der Möhlen; Tom van der Poll; J Jansen; Marcel Levi; Sander J H van Deventer
Release of bactericidal/permeability-increasing protein in experimental endotoxemia and clinical sepsis. Role of tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4969-73.
1996: Tom van der Poll; J Jansen; Marcel Levi; Hugo ten Cate; C Erik Hack; Lucien A Aarden; JW ten Cate; Sander J H van Deventer
Interleukin 10 release during endotoxaemia in chimpanzees: role of platelet-activating factor and interleukin 6.
Scandinavian journal of immunology 1996;43(1):122-5.
1995: M H Godfried; Tom van der Poll; Jan W Mulder; Gerrit Jan Weverling; Erik Endert; Joep M A Lange; Hans P Sauerwein
Soluble tumor necrosis factor receptors as surrogate markers for the assessment of zidovudine treatment in asymptomatic HIV-1 infection.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1995;10(5):531-9.
1995: M H Godfried; Johannes A Romijn; Tom van der Poll; Gerrit Jan Weverling; EP Corssmit; Erik Endert; J K Eeftinck Schattenkerk; Hans P Sauerwein
Soluble receptors for tumor necrosis factor are markers for clinical course but not for major metabolic changes in human immunodeficiency virus infection.
Metabolism: clinical and experimental 1995;44(12):1564-9.
1995: Tom van der Poll; Eduard E Zijlstra; M Mevissen
Interleukin 6 during active visceral leishmaniasis and after treatment.
Clinical immunology and immunopathology 1995;77(1):111-4.
1995: J M Stouthard; Johannes A Romijn; Tom van der Poll; Erik Endert; S Klein; P J M Bakker; C H Veenhof; Hans P Sauerwein
Endocrinologic and metabolic effects of interleukin-6 in humans.
The American journal of physiology 1995;268(5 Pt 1):E813-9.
1995: Bart J Biemond; Marcel Levi; Hugo ten Cate; Tom van der Poll; Harry R Büller; C Erik Hack; JW ten Cate
Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: effect of interventions in the cytokine and coagulation cascades.
Clinical science (London, England : 1979) 1995;88(5):587-94.
1995: Tom van der Poll; Marcel Levi; Hugo ten Cate; J Jansen; Bart J Biemond; B L Haagmans; A Eerenberg; Sander J H van Deventer; C Erik Hack; JW ten Cate
Effect of postponed treatment with an anti-tumour necrosis factor (TNF) F(ab')2 fragment on endotoxin-induced cytokine and neutrophil responses in chimpanzees.
Clinical and experimental immunology 1995;100(1):21-5.
1995: Eduard E Zijlstra; Tom van der Poll; M Mevissen
Soluble receptors for tumor necrosis factor as markers of disease activity in visceral leishmaniasis.
The Journal of infectious diseases 1995;171(2):498-501.
1995: Bart J Biemond; Marcel Levi; Hugo ten Cate; H R Soule; L D Morris; D L Foster; C A Bogowitz; Tom van der Poll; Harry R Büller; JW ten Cate
Complete inhibition of endotoxin-induced coagulation activation in chimpanzees with a monoclonal Fab fragment against factor VII/VIIa.
Thrombosis and haemostasis 1995;73(2):223-30.
1995: J Jansen; Tom van der Poll; Marcel Levi; Hugo ten Cate; H Gallati; JW ten Cate; Sander J H van Deventer
Inhibition of the release of soluble tumor necrosis factor receptors in experimental endotoxemia by an anti-tumor necrosis factor-alpha antibody.
Journal of clinical immunology 1995;15(1):45-50.
1994: Tom van der Poll; J Jansen; Marcel Levi; Hugo ten Cate; JW ten Cate; Sander J H van Deventer
Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees.
The Journal of experimental medicine 1994;180(5):1985-8.
1994: J M Stouthard; Tom van der Poll; Erik Endert; P J M Bakker; C H Veenhof; Hans P Sauerwein; Johannes A Romijn
Effects of acute and chronic interleukin-6 administration on thyroid hormone metabolism in humans.
The Journal of clinical endocrinology and metabolism 1994;79(5):1342-6.
1994: R Koopmans; F J Hoek; S J van Deventer; Tom van der Poll
Model for whole body production of tumour necrosis factor-alpha in experimental endotoxaemia in healthy subjects.
Clinical science (London, England : 1979) 1994;87(4):459-65.
1994: Hugo ten Cate; B E Schenk; Bart J Biemond; Marcel Levi; Tom van der Poll; H R Buller; JW ten Cate
A review of studies of the activation of the blood coagulation mechanism in chimpanzees (Pan troglodytes).
Journal of medical primatology 1994;23(5):280-4.
1994: Tom van der Poll; J Jansen; Erik Endert; Hans P Sauerwein; Sander J H van Deventer
Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood.
Infection and immunity 1994;62(5):2046-50.
1994: Tom van der Poll; Marcel Levi; C Erik Hack; Hugo ten Cate; Sander J H van Deventer; A J Eerenberg; Els R de Groot; J Jansen; H Gallati; Harry R Büller
Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees.
The Journal of experimental medicine 1994;179(4):1253-9.
1994: M H Godfried; Tom van der Poll; Gerrit Jan Weverling; Jan W Mulder; J Jansen; Sander J H van Deventer; Hans P Sauerwein
Soluble receptors for tumor necrosis factor as predictors of progression to AIDS in asymptomatic human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 1994;169(4):739-45.
1994: Tom van der Poll; Sander J H van Deventer; Hugo ten Cate; Marcel Levi; JW ten Cate
Tumor necrosis factor is involved in the appearance of interleukin-1 receptor antagonist in endotoxemia.
The Journal of infectious diseases 1994;169(3):665-7.
1994: B Kuipers; Tom van der Poll; Marcel Levi; Sander J H van Deventer; Hugo ten Cate; Y Imai; C Erik Hack; JW ten Cate
Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2438-46.
1994: Tom van der Poll; Marcel Levi; Sander J H van Deventer; Hugo ten Cate; B L Haagmans; Bart J Biemond; Harry R Büller; C Erik Hack; JW ten Cate
Differential effects of anti-tumor necrosis factor monoclonal antibodies on systemic inflammatory responses in experimental endotoxemia in chimpanzees.
Blood 1994;83(2):446-51.
1994: Marcel Levi; Hugo ten Cate; K A Bauer; Tom van der Poll; T S Edgington; Harry R Büller; Sander J H van Deventer; C Erik Hack; JW ten Cate; R D Rosenberg
Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.
The Journal of clinical investigation 1994;93(1):114-20.
1994: Tom van der Poll; Marcel Levi; Hugo ten Cate; Sander J H van Deventer
The role of tumor necrosis factor in systemic inflammatory responses in primate endotoxemia.
Progress in clinical and biological research 1994;388():425-33.
1994: J Jansen; Tom van der Poll; Sander J H van Deventer
Endotoxin and the release of tumor necrosis factor receptors.
Progress in clinical and biological research 1994;388():383-97.
1994: Hugo ten Cate; Marcel Levi; Tom van der Poll; Bart J Biemond; Sander J H van Deventer; H R Buller; JW ten Cate
Inhibition of extrinsic coagulation activation in endotoxemia; therapeutic implications.
Progress in clinical and biological research 1994;388():215-9.
1993: Peter Portegies; M H Godfried; R Q Hintzen; J Stam; Tom van der Poll; Margreet Bakker; Sander J H van Deventer; René A W van Lier; Jaap Goudsmit
Low levels of specific T cell activation marker CD27 accompanied by elevated levels of markers for non-specific immune activation in the cerebrospinal fluid of patients with AIDS dementia complex.
Journal of neuroimmunology 1993;48(2):241-7.
1993: Tom van der Poll; J Jansen; D van Leenen; M von der Möhlen; Marcel Levi; Hugo ten Cate; H Gallati; JW ten Cate; Sander J H van Deventer
Release of soluble receptors for tumor necrosis factor in clinical sepsis and experimental endotoxemia.
The Journal of infectious diseases 1993;168(4):955-60.
1993: D van Leenen; Tom van der Poll; Marcel Levi; Hugo ten Cate; Sander J H van Deventer; C Erik Hack; Lucien A Aarden; JW ten Cate
Pentoxifylline attenuates neutrophil activation in experimental endotoxemia in chimpanzees.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):2318-25.
1993: Tom van der Poll; Johannes A Romijn; Erik Endert; Hans P Sauerwein
Effects of tumor necrosis factor on the hypothalamic-pituitary-testicular axis in healthy men.
Metabolism: clinical and experimental 1993;42(3):303-7.
1993: Sander J H van Deventer; M Hart; Tom van der Poll; C Erik Hack; L A Aarden
Endotoxin and tumor necrosis factor-alpha-induced interleukin-8 release in humans.
The Journal of infectious diseases 1993;167(2):461-54.
1993: M H Godfried; Tom van der Poll; J Jansen; J A Romijin; J K Schattenkerk; Erik Endert; Sander J H van Deventer; Hans P Sauerwein
Soluble receptors for tumour necrosis factor: a putative marker of disease progression in HIV infection.
AIDS (London, England) 1993;7(1):33-6.
1992: Tom van der Poll; Sander J H van Deventer; G Pasterkamp; Jan A van Mourik; Harry R Büller; JW ten Cate
Tumor necrosis factor induces von Willebrand factor release in healthy humans.
Thrombosis and haemostasis 1992;67(6):623-6.
1992: Tom van der Poll; Sander J H van Deventer; C Erik Hack; Gertjan Wolbink; Lucien A Aarden; Harry R Büller; JW ten Cate
Effects on leukocytes after injection of tumor necrosis factor into healthy humans.
Blood 1992;79(3):693-8.
1991: Tom van der Poll; Johannes A Romijn; Erik Endert; J J Borm; H R Büller; Hans P Sauerwein
Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans.
The American journal of physiology 1991;261(4 Pt 1):E457-65.
1991: Tom van der Poll; Sander J H van Deventer; H R Büller; A Sturk; JW ten Cate
Comparison of the early dynamics of systemic prostacyclin release after administration of tumor necrosis factor and endotoxin to healthy humans.
The Journal of infectious diseases 1991;164(3):599-601.
1991: Tom van der Poll; Marcel Levi; Harry R Büller; Sander J H van Deventer; J P de Boer; C Erik Hack; JW ten Cate
Fibrinolytic response to tumor necrosis factor in healthy subjects.
The Journal of experimental medicine 1991;174(3):729-32.
1991: Tom van der Poll; Sander J H van Deventer; Harry R Büller; Augueste Sturk; JW ten Cate
Comparison of the early dynamics of coagulation activation after injection of endotoxin and tumor necrosis factor in healthy humans.
Progress in clinical and biological research 1991;367():55-60.
1990: Tom van der Poll; Johannes A Romijn; Wilmar M Wiersinga; Hans P Sauerwein
Tumor necrosis factor: a putative mediator of the sick euthyroid syndrome in man.
The Journal of clinical endocrinology and metabolism 1990;71(6):1567-72.
1990: Tom van der Poll; Harry R Büller; Hugo ten Cate; C H Wortel; K A Bauer; Sander J H van Deventer; C Erik Hack; Hans P Sauerwein; R D Rosenberg; JW ten Cate
Activation of coagulation after administration of tumor necrosis factor to normal subjects.
The New England journal of medicine 1990;322(23):1622-7.