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Jolanda van der Velden

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Paul J M Wijnker; Cristobal G dos Remedios; Darren Foster; Aisha H Frazier; Anne M Murphy; Ger J M Stienen; Allison L Tsao; Jolanda van der Velden
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
Frances De Man; Peter Dorfmuller; Ly Tu; Elie Fadel; Charlène François; a boonstra; Martin Louis Handoko; Marc Humbert; Frédéric Perros; Piet E Postmus; Silvia Rain; Gerrina Ruiter; Ingrid Schalij; Gérald Simonneau; Ly Tu; Jolanda van der Velden; Anton Vonk-Noordegraaf; Christophe Guignabert
Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.
Loek van Heerebeek; Freek W A Verheugt; Aernout Somsen; Ger J M Stienen; Jolanda van der Velden; Mark P V Begieneman; Jean G F Bronzwaer; Inês Falcão-Pires; Nazha Hamdani; Gerrit J Laarman; Adelino F Leite-Moreira; Hans W M Niessen; Walter J Paulus
Low myocardial protein kinase G activity in heart failure with preserved ejection fraction.

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2013: Paul J M Wijnker; Cristobal G dos Remedios; Darren Foster; Aisha H Frazier; Anne M Murphy; Ger J M Stienen; Allison L Tsao; Jolanda van der Velden
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2013;304(2):H260-8.
2012: Frances De Man; Peter Dorfmuller; Ly Tu; Elie Fadel; Charlène François; a boonstra; Martin Louis Handoko; Marc Humbert; Frédéric Perros; Piet E Postmus; Silvia Rain; Gerrina Ruiter; Ingrid Schalij; Gérald Simonneau; Ly Tu; Jolanda van der Velden; Anton Vonk-Noordegraaf; Christophe Guignabert
Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2012;186(8):780-9.
2012: Loek van Heerebeek; Freek W A Verheugt; Aernout Somsen; Ger J M Stienen; Jolanda van der Velden; Mark P V Begieneman; Jean G F Bronzwaer; Inês Falcão-Pires; Nazha Hamdani; Gerrit J Laarman; Adelino F Leite-Moreira; Hans W M Niessen; Walter J Paulus
Low myocardial protein kinase G activity in heart failure with preserved ejection fraction.
Circulation 2012;126(7):830-9.
2012: Diederik W D Kuster; Amira Cholid Bawazeer; Nicky M Boontje; Max Goebel; Ruud Zaremba; Jolanda van der Velden
Cardiac myosin binding protein C phosphorylation in cardiac disease.
Journal of muscle research and cell motility 2012;33(1):43-52.
2012: Wessel P Brouwer; Imke Christiaans; Tjeerd Germans; Maaike C Head; Martijn W Heymans; Arjan C Houweling; Jolanda van der Velden; Arthur A Wilde; Albert C van Rossum
Multiple myocardial crypts on modified long-axis view are a specific finding in pre-hypertrophic HCM mutation carriers.
European heart journal cardiovascular Imaging 2012;13(4):292-7.
2012: Sabine J van Dijk; Marjon van Slegtenhorst; Nicky M Boontje; Lucie Carrier; Dennis Dooijes; Cris dos Remedios; Diederik W D Kuster; Michelle Michels; Aref Najafi; E Rosalie Paalberends; Sakthivel Sadayappan; Ger J M Stienen; Folkert J Ten Cate; Jolanda van der Velden
Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function.
Circulation. Heart failure 2012;5(1):36-46.
2012: Frances De Man; Martin Louis Handoko; Walter J Paulus; Pieter E Postmus; Ingrid Schalij; Joris J M van Ballegoij; Jolanda van der Velden; Sylvia J P Bogaards; Nico Westerhof; Anton Vonk-Noordegraaf
Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension.
Circulation. Heart failure 2012;5(1):97-105.
2011: Stefan A J Timmer; Jolanda van der Velden; Arthur A M Wilde; Wessel P Brouwer; Imke Christiaans; Tjeerd Germans; Paul Knaapen; Adriaan A Lammertsma; Mark Lubberink; Albert C van Rossum
Carriers of the hypertrophic cardiomyopathy MYBPC3 mutation are characterized by reduced myocardial efficiency in the absence of hypertrophy and microvascular dysfunction.
European journal of heart failure 2011;13(12):1283-9.
2011: Paul J M Wijnker; Peter Boknik; Cris dos Remedios; Ulrich Gergs; Frank U Müller; Joachim Neumann; Wilhelm Schmitz; Jürgen R Sindermann; Ger J M Stienen; Jolanda van der Velden; Uwe Kirchhefer
Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium.
Journal of muscle research and cell motility 2011;32(3):221-33.
2011: Inês Falcão-Pires; Cristina Gavina; Nazha Hamdani; Adelino F Leite-Moreira; Hans W M Niessen; Casper G Schalkwijk; Ger J M Stienen; Jolanda van der Velden; Loek van Heerebeek; Attila Borbély; Walter J Paulus
Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.
Circulation 2011;124(10):1151-9.
2011: Jolanda van der Velden
Diastolic myofilament dysfunction in the failing human heart.
Pflügers Archiv : European journal of physiology 2011;462(1):155-63.
2011: Elza D van Deel; Martine de Boer; Diederik W Kuster; Nicky M Boontje; Patricia Holemans; Karin R Sipido; Jolanda van der Velden; Dirk J Duncker
Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis.
Journal of molecular and cellular cardiology 2011;50(6):1017-25.
2011: Wessel P Brouwer; Sabine J van Dijk; Ger J M Stienen; Albert C van Rossum; Jolanda van der Velden; Tjeerd Germans
The development of familial hypertrophic cardiomyopathy: from mutation to bedside.
European journal of clinical investigation 2011;41(5):568-78.
2011: Diederik W D Kuster; Daphne Merkus; Jolanda van der Velden; Adrie J M Verhoeven; Dirk J Duncker
'Integrative Physiology 2.0': integration of systems biology into physiology and its application to cardiovascular homeostasis.
The Journal of physiology 2011;589(Pt 5):1037-45.
2011: Jolanda van der Velden; Nicky M Boontje; Vincent de Beer; Nazha Hamdani; Wolfgang A Linke; Dirk Duncker; Ger J M Stienen; Dirk J Duncker
Transmural heterogeneity of myofilament function and sarcomeric protein phosphorylation in remodeled myocardium of pigs with a recent myocardial infarction.
Frontiers in physiology 2011;2():83.
2010: Alexandra Belus; Nicoletta Piroddi; Cecilia Ferrantini; Chiara Tesi; Olivier Cazorla; Luana Toniolo; Maurice Drost; Giulia Mearini; Lucie Carrier; Alessandra Rossi; Alessandro Mugelli; Elisabetta Cerbai; Jolanda van der Velden; Corrado Poggesi
Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils.
Circulation research 2010;107(1):144-52.
2010: Viola Kooij; Martina Saes; Kornelia Jaquet; Ruud Zaremba; Darren Foster; Anne M Murphy; Cris Dos Remedios; Jolanda van der Velden; Ger J M Stienen
Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background.
Journal of molecular and cellular cardiology 2010;48(5):954-63.
2010: Viola Kooij; Nicky Boontje; Ruud Zaremba; Kornelia Jaquet; Cris dos Remedios; Ger J M Stienen; Jolanda van der Velden
Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium.
Basic research in cardiology 2010;105(2):289-300.
2010: Tjeerd Germans; Iris Rüssel; Marco J W Götte; Marieke D Spreeuwenberg; Pieter A Doevendans; Yigal M Pinto; Rob J van der Geest; Jolanda van der Velden; Arthur A M Wilde; Albert C van Rossum
How do hypertrophic cardiomyopathy mutations affect myocardial function in carriers with normal wall thickness? Assessment with cardiovascular magnetic resonance.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2010;12():13.
2009: Sabine J van Dijk; Rozemarije A Holewijn; Anouk Tebeest; Cris Dos Remedios; Ger J M Stienen; Jolanda van der Velden
A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients.
Journal of muscle research and cell motility 2009;30(7-8):299-302.
2009: Melissa Swinnen; Davy Vanhoutte; Geert C Van Almen; Nazha Hamdani; Mark W M Schellings; Jan D'hooge; Jolanda van der Velden; Matthew S Weaver; E Helene Sage; Paul Bornstein; Fons K Verheyen; Thierry VandenDriessche; Marinee K Chuah; Dirk Westermann; Walter J Paulus; Frans Van de Werf; Blanche Schroen; Peter Carmeliet; Yigal M Pinto; Stephane Heymans
Absence of thrombospondin-2 causes age-related dilated cardiomyopathy.
Circulation 2009;120(16):1585-97.
2009: Dirk J Duncker; Nicky M Boontje; Dirk Duncker; Amanda Versteilen; Judith Krysiak; Giulia Mearini; Ali El-Armouche; Vincent de Beer; Jos M J Lamers; Lucie Carrier; Lori A Walker; Wolfgang A Linke; Ger J M Stienen; Jolanda van der Velden
Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling.
Circulation. Heart failure 2009;2(3):233-42.
2009: Nazha Hamdani; Jolanda van der Velden
Lack of specificity of antibodies directed against human beta-adrenergic receptors.
Naunyn-Schmiedeberg's archives of pharmacology 2009;379(4):403-7.
2009: Attila Borbély; Ines Falcao-Pires; Loek van Heerebeek; Nazha Hamdani; István Ferenc Édes; Cristina Gavina; Adelino F Leite-Moreira; Jean G F Bronzwaer; Zoltán Papp; Jolanda van der Velden; Ger J M Stienen; Walter J Paulus
Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.
Circulation research 2009;104(6):780-6.
2009: Sabine J van Dijk; Dennis Dooijes; Cris dos Remedios; Michelle Michels; Jos M J Lamers; Saul Winegrad; Saskia Schlossarek; Lucie Carrier; Folkert J Ten Cate; Ger J M Stienen; Jolanda van der Velden
Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction.
Circulation 2009;119(11):1473-83.
2009: Charissa E van den Brom; Marc C Huisman; Ronald Vlasblom; Nicky M Boontje; Suzanne Duijst; Mark Lubberink; Carla F M Molthoff; Adriaan A Lammertsma; Jolanda van der Velden; Christa Boer; D Margriet Ouwens; Michaela Diamant
Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: studies using positron emission tomography.
Cardiovascular diabetology 2009;8():39.
2008: Zita Hertelendi; Attila Tóth; Attila Borbély; Zoltán Galajda; Jolanda van der Velden; Ger J M Stienen; István Ferenc Édes; Zoltán Papp
Oxidation of myofilament protein sulfhydryl groups reduces the contractile force and its Ca2+ sensitivity in human cardiomyocytes.
Antioxidants & redox signaling 2008;10(7):1175-84.
2008: Cristina Chimenti; Nazha Hamdani; Nicky M Boontje; Francesco DeCobelli; Antonio Esposito; Jean G F Bronzwaer; Ger J M Stienen; Matteo A Russo; Walter J Paulus; Andrea Frustaci; Jolanda van der Velden
Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease.
The American journal of pathology 2008;172(6):1482-90.
2008: Sabine J van Dijk; Nazha Hamdani; Ger J M Stienen; Jolanda van der Velden
Myocardial adaptations in the failing heart: cause or consequence?
Journal of muscle research and cell motility 2008;29(6-8):159-62.
2008: Loek van Heerebeek; Nazha Hamdani; Martin Louis Handoko; Ines Falcao-Pires; René J P Musters; Koba Kupreishvili; Alexander J J IJsselmuiden; Casper G Schalkwijk; Jean G F Bronzwaer; Michaela Diamant; Attila Borbély; Jolanda van der Velden; Ger J M Stienen; Gert-Jan Laarman; Hans W M Niessen; Walter J Paulus
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension.
Circulation 2008;117(1):43-51.
2007: S Cora Verduyn; Ruud Zaremba; Jolanda van der Velden; Ger J M Stienen
Effects of contractile protein phosphorylation on force development in permeabilized rat cardiac myocytes.
Basic research in cardiology 2007;102(6):476-87.
2007: Ruud Zaremba; Dirk Duncker; Nazha Hamdani; Jos M J Lamers; Walter J Paulus; Cris Dos Remedios; Dirk J Duncker; Ger J M Stienen; Jolanda van der Velden
Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies.
Proteomics. Clinical applications 2007;1(10):1285-90.
2007: Regis Lamberts; Nazha Hamdani; Tenoedj W Soekhoe; Nicky M Boontje; Ruud Zaremba; Lori A Walker; Pieter P de Tombe; Jolanda van der Velden; Ger J M Stienen
Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium.
The Journal of physiology 2007;582(Pt 2):695-709.
2007: István Ferenc Edes; Dániel Czuriga; Gábor Csányi; Stefan Chlopicki; Fabio A Recchia; Attila Borbély; Zoltán Galajda; István Ferenc Édes; Jolanda van der Velden; Ger J M Stienen; Zoltán Papp
Rate of tension redevelopment is not modulated by sarcomere length in permeabilized human, murine, and porcine cardiomyocytes.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(1):R20-9.
2007: Virginie Bito; Jolanda van der Velden; Piet Claus; Christoph Dommke; Alfons Van Lommel; Luc Mortelmans; Erik Verbeken; Bart Bijnens; Ger J M Stienen; Karin R Sipido
Reduced force generating capacity in myocytes from chronically ischemic, hibernating myocardium.
Circulation research 2007;100(2):229-37.
2006: Nadiya A Narolska; Nicoletta Piroddi; Alexandra Belus; Nicky M Boontje; Beatrice Scellini; Sascha Deppermann; Ruud Zaremba; René J P Musters; Cris dos Remedios; Kornelia Jaquet; Darren Foster; Anne M Murphy; Jennifer E Van Eyk; Chiara Tesi; Corrado Poggesi; Jolanda van der Velden; Ger J M Stienen
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.
Circulation research 2006;99(9):1012-20.
2006: S Eiras; Nadiya A Narolska; RB van Loon; Nicky M Boontje; Ruud Zaremba; Connie R Jimenez; Frans C Visser; Wim Stooker; Jolanda van der Velden; Ger J M Stienen
Alterations in contractile protein composition and function in human atrial dilatation and atrial fibrillation.
Journal of molecular and cellular cardiology 2006;41(3):467-77.
2006: Loek van Heerebeek; Attila Borbély; Hans W M Niessen; Jean G F Bronzwaer; Jolanda van der Velden; Ger J M Stienen; Wolfgang A Linke; Gert-Jan Laarman; Walter J Paulus
Myocardial structure and function differ in systolic and diastolic heart failure.
Circulation 2006;113(16):1966-73.
2006: Nicoletta Piroddi; Alexandra Belus; S Eiras; Chiara Tesi; Jolanda van der Velden; Corrado Poggesi; Ger J M Stienen
No direct effect of creatine phosphate on the cross-bridge cycle in cardiac myofibrils.
Pflügers Archiv : European journal of physiology 2006;452(1):3-6.
2006: Jolanda van der Velden; Nadiya A Narolska; Regis Lamberts; Nicky M Boontje; Attila Borbély; Ruud Zaremba; Jean G F Bronzwaer; Zoltán Papp; Kornelia Jaquet; Walter J Paulus; Ger J M Stienen
Functional effects of protein kinase C-mediated myofilament phosphorylation in human myocardium.
Cardiovascular research 2006;69(4):876-87.
2005: Attila Borbély; Attila Tóth; István Ferenc Édes; Laszlo Virag; Julius Gy Papp; András Varró; Walter J Paulus; Jolanda van der Velden; Ger J M Stienen; Zoltán Papp
Peroxynitrite-induced alpha-actinin nitration and contractile alterations in isolated human myocardial cells.
Cardiovascular research 2005;67(2):225-33.
2005: Attila Borbély; Jolanda van der Velden; Zoltán Papp; Jean G F Bronzwaer; István Ferenc Édes; Ger J M Stienen; Walter J Paulus
Cardiomyocyte stiffness in diastolic heart failure.
Circulation 2005;111(6):774-81.
2005: Nadiya A Narolska; S Eiras; RB van Loon; Nicky M Boontje; Ruud Zaremba; S R Spiegelen Berg; Wim Stooker; M A J M Huybregts; Frans C Visser; Jolanda van der Velden; Ger J M Stienen
Myosin heavy chain composition and the economy of contraction in healthy and diseased human myocardium.
Journal of muscle research and cell motility 2005;26(1):39-48.
2005: Nadiya A Narolska; RB van Loon; Nicky M Boontje; Ruud Zaremba; S Eiras Penas; J Russell; Stefan R Spiegelenberg; M A J M Huybregts; Frans C Visser; JW de Jong; Jolanda van der Velden; Ger J M Stienen
Myocardial contraction is 5-fold more economical in ventricular than in atrial human tissue.
Cardiovascular research 2005;65(1):221-9.
2004: Virginie Bito; Frank R Heinzel; Frank Weidemann; Christoph Dommke; Jolanda van der Velden; Erik Verbeken; Piet Claus; Bart Bijnens; Ivan De Scheerder; Ger J M Stienen; George R Sutherland; Karin R Sipido
Cellular mechanisms of contractile dysfunction in hibernating myocardium.
Circulation research 2004;94(6):794-801.
2004: Zoltán Papp; Jolanda van der Velden; Attila Borbély; István Ferenc Édes; Ger J M Stienen
Effects of Ca2+ -sensitizers in permeabilized cardiac myocytes from donor and end-stage failing human hearts.
Journal of muscle research and cell motility 2004;25(3):219-24.
2003: Jolanda van der Velden; Zoltán Papp; Nicky M Boontje; Ruud Zaremba; JW de Jong; Paul Janssen; G Hasenfuss; Ger J M Stienen
The effect of myosin light chain 2 dephosphorylation on Ca2+ -sensitivity of force is enhanced in failing human hearts.
Cardiovascular research 2003;57(2):505-14.
2003: Jolanda van der Velden; Zoltán Papp; Nicky M Boontje; Ruud Zaremba; JW de Jong; Paul Janssen; G Hasenfuss; Ger J M Stienen
Myosin light chain composition in non-failing donor and end-stage failing human ventricular myocardium.
Advances in experimental medicine and biology 2003;538():3-15.
2003: Jolanda van der Velden; Zoltán Papp; Ruud Zaremba; Nicky M Boontje; JW de Jong; VJ Owen; P B J Burton; P Goldmann; Kornelia Jaquet; Ger J M Stienen
Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins.
Cardiovascular research 2003;57(1):37-47.
2002: Jolanda van der Velden; Nicky M Boontje; Zoltán Papp; Lucas J Klein; Frans C Visser; JW de Jong; VJ Owen; P B J Burton; Ger J M Stienen
Calcium sensitivity of force in human ventricular cardiomyocytes from donor and failing hearts.
Basic research in cardiology 2002;97 Suppl 1():I118-26.
2001: Jolanda van der Velden; Lucas J Klein; Ruud Zaremba; Nicky M Boontje; M A J M Huybregts; Wim Stooker; León Eijsman; JW de Jong; Cees A Visser; Frans C Visser; Ger J M Stienen
Effects of calcium, inorganic phosphate, and pH on isometric force in single skinned cardiomyocytes from donor and failing human hearts.
Circulation 2001;104(10):1140-6.
2001: Fabio Abbate; Jolanda van der Velden; Ger J M Stienen; Arnold De Haan
Post-tetanic potentiation increases energy cost to a higher extent than work in rat fast skeletal muscle.
Journal of muscle research and cell motility 2001;22(8):703-10.
2000: Jolanda van der Velden; JW de Jong; VJ Owen; P B J Burton; Ger J M Stienen
Effect of protein kinase A on calcium sensitivity of force and its sarcomere length dependence in human cardiomyocytes.
Cardiovascular research 2000;46(3):487-95.
1999: Jolanda van der Velden; Lucas J Klein; MW van der Bijl; M A J M Huybregts; Wim Stooker; J Witkop; León Eijsman; Cees A Visser; Frans C Visser; Ger J M Stienen
Isometric tension development and its calcium sensitivity in skinned myocyte-sized preparations from different regions of the human heart.
Cardiovascular research 1999;42(3):706-19.
1999: Jolanda van der Velden; Piet Borgdorff; Ger J M Stienen
Minoxidil-induced cardiac hypertrophy in guinea pigs.
Cellular and molecular life sciences : CMLS 1999;55(5):788-98.
1998: Jolanda van der Velden; Lucas J Klein; MW van der Bijl; M A J M Huybregts; Wim Stooker; J Witkop; León Eijsman; Cees A Visser; Frans C Visser; Ger J M Stienen
Force production in mechanically isolated cardiac myocytes from human ventricular muscle tissue.
Cardiovascular research 1998;38(2):414-23.
1998: Jolanda van der Velden; A F Moorman; Ger J M Stienen
Age-dependent changes in myosin composition correlate with enhanced economy of contraction in guinea-pig hearts.
The Journal of physiology 1998;507 ( Pt 2)():497-510.
1995: M W de Waal; François G Schellevis; Jolanda van der Velden
[Family physician consultation by patients with rheumatoid arthritis or gonarthrosis/coxarthrosis].
Nederlands tijdschrift voor geneeskunde 1995;139(26):1331-5.
1994: François G Schellevis; E H Van de Lisdonk; Jolanda van der Velden; S H Hoogbergen; Jacques Th M van Eijk; C Van Weel
Consultation rates and incidence of intercurrent morbidity among patients with chronic disease in general practice.
The British journal of general practice : the journal of the Royal College of General Practitioners 1994;44(383):259-62.
1993: François G Schellevis; Jolanda van der Velden; E van de Lisdonk; Jacques Th M van Eijk; C van Weel
Comorbidity of chronic diseases in general practice.
Journal of clinical epidemiology 1993;46(5):469-73.
1993: François G Schellevis; E van de Lisdonk; Jolanda van der Velden; Jacques Th M van Eijk; C van Weel
Validity of diagnoses of chronic diseases in general practice. The application of diagnostic criteria.
Journal of clinical epidemiology 1993;46(5):461-8.